PTM - CPLM Gene Name UniProt ID Type Position Code TNIP1; KIAA0113; NAF1 Q15025 Acetylation 257 K TNIP1; KIAA0113; NAF1 Q15025 Ubiquitination 496 K

PTM - dbPAF Gene Name UniProt ID Position Type Species TNIP1; KIAA0113; NAF1 Q15025 261 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 266 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 284 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 336 T Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 350 T Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 385 T Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 397 Y Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 403 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 406 T Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 428 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 431 T Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 434 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 435 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 438 T Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 442 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 552 Y Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 568 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 596 Y Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 627 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 77 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 79 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 82 S Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 97 T Homo sapiens(Human) TNIP1; KIAA0113; NAF1 Q15025 99 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q15025 K257-ac Acetylation LLMSNGNkEGASGRP Q15025 K463-ac Acetylation VTQNELLkQQVkIFE Q15025 K467-ac Acetylation ELLkQQVkIFEEDFQ Q15025 R571-m1 Methylation FEDWsQIrYPPPPMA Q15025 R599-m2 Methylation HLPEyTWrLPCGGVR Q15025 R599-m1 Methylation HLPEyTWrLPCGGVR Q15025 S15-p Phosphorylation RIYDPGGsVPsGEAS Q15025 S18-p Phosphorylation DPGGsVPsGEASAAF Q15025 S77-p Phosphorylation NELLPPPsPsLGSFD Q15025 S79-p Phosphorylation LLPPPsPsLGSFDPL Q15025 S99-p Phosphorylation KDSNVTAsPTAPACP Q15025 S169-p Phosphorylation QRLETTLsVCAEEPD Q15025 S266-p Phosphorylation GASGRPGsPKMEGTG Q15025 S284-p Phosphorylation VAGQQQAsVTAGKVP Q15025 T336-p Phosphorylation QQYEQKItELRQKLA Q15025 T350-p Phosphorylation ADLQKQVtDLEAERE Q15025 T385-p Phosphorylation ETDKEQLtAEAKELR Q15025 S403-p Phosphorylation KYLQDQLsPLTRQRE Q15025 T431-p Phosphorylation EEALSIQtPPssPPt Q15025 S434-p Phosphorylation LSIQtPPssPPtAFG Q15025 S435-p Phosphorylation SIQtPPssPPtAFGs Q15025 T438-p Phosphorylation tPPssPPtAFGsPEG Q15025 S442-p Phosphorylation sPPtAFGsPEGAGAL Q15025 Y552-p Phosphorylation CGAYPYAyPPMPAMV Q15025 S568-p Phosphorylation HHGFEDWsQIrYPPP Q15025 Y596-p Phosphorylation RLFHLPEyTWrLPCG Q15025 S627-p Phosphorylation ARPTEPEsPKNDREG Q15025 K223-ub Ubiquitination RKENEALkAKLDKGL Q15025 K301-ub Ubiquitination VALGAAEkKVKMLEQ Q15025 K496-ub Ubiquitination ELKKQVEkLQAQVTL

PTM - dbPTM UniProt ID Position Code Type Resources References Q15025 99 S Phosphorylation Swiss-Prot 1010711 19413330 Q15025 403 S Phosphorylation Swiss-Prot 1010711 16964243;18669648 Q15025 438 T Phosphorylation Swiss-Prot 1010711 19690332 Q15025 552 Y Phosphorylation Swiss-Prot 1010711 17632516 Q15025 403 S Phosphorylation PhosphoELM.10011 18669648 Q15025 431 T Phosphorylation PhosphoELM.10011 18669648 Q15025 438 T Phosphorylation PhosphoELM.10011 18669648 Q15025 496 K Ubiquitylation Phosphositeplus.1010730 21906983 Q15025 257 K Acetylation Phosphositeplus.1010730 20167786 Q15025 266 S Phosphorylation Phosphositeplus.1010730 20068231 Q15025 403 S Phosphorylation Phosphositeplus.1010730 16964243;18669648;19664994;20068231;22115753 Q15025 435 S Phosphorylation Phosphositeplus.1010730 19690332 Q15025 442 S Phosphorylation Phosphositeplus.1010730 20068231;22115753 Q15025 568 S Phosphorylation Phosphositeplus.1010730 19581576 Q15025 431 T Phosphorylation Phosphositeplus.1010730 19690332;22115753 Q15025 438 T Phosphorylation Phosphositeplus.1010730 18669648;19690332;20068231 Q15025 77 S Phosphorylation HPRD 9.0 20068231 Q15025 99 S Phosphorylation HPRD 9.0 19413330 Q15025 266 S Phosphorylation HPRD 9.0 20068231 Q15025 403 S Phosphorylation HPRD 9.0 18669648,19664994,16964243,20068231 Q15025 434 S Phosphorylation HPRD 9.0 20068231 Q15025 435 S Phosphorylation HPRD 9.0 20068231 Q15025 442 S Phosphorylation HPRD 9.0 20068231 Q15025 431 T Phosphorylation HPRD 9.0 18669648,20068231 Q15025 438 T Phosphorylation HPRD 9.0 18669648,20068231

PTM - HPRD Symbol Position Code Type References TNIP1 266 S Phosphorylation 20068231 TNIP1 403 S Phosphorylation 18669648,19664994,16964243,20068231 TNIP1 431 T Phosphorylation 18669648,20068231 TNIP1 434 S Phosphorylation 20068231 TNIP1 435 S Phosphorylation 20068231 TNIP1 438 T Phosphorylation 18669648,20068231 TNIP1 442 S Phosphorylation 20068231 TNIP1 77 S Phosphorylation 20068231 TNIP1 99 S Phosphorylation 19413330

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q15025 403 S 18669648 HTP Phosphorylation Q15025 431 T 18669648 HTP Phosphorylation Q15025 438 T 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q15025 77 Phosphoserine 24275569 Q15025 284 Phosphoserine 24275569 Q15025 403 Phosphoserine 16964243;18669648;20068231;23186163 Q15025 438 Phosphothreonine 19690332 Q15025 442 Phosphoserine 20068231 Q15025 552 Phosphotyrosine 17632516 Q15025 599 Asymmetric dimethylarginine; alternate 24129315 Q15025 599 Omega-N-methylarginine; alternate 24129315 Q15025 627 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type TNIP1 IPI00216616 S 261 GNKEGApSGRPGSP phosphorylation TNIP1 IPI00216616 S 266 ASGRPGpSPKMEGT phosphorylation TNIP1 IPI00216616 S 403 YLQDQLpSPLTRQR phosphorylation TNIP1 IPI00216616 S 435 IQTPPSpSPPTAFG phosphorylation TNIP1 IPI00216616 S 442 PPTAFGpSPEGAGA phosphorylation TNIP1 IPI00216616 S 77 ELLPPPpSPSLGSF phosphorylation TNIP1 IPI00216616 T 431 EALSIQpTPPSSPP phosphorylation TNIP1 IPI00216616 T 438 PPSSPPpTAFGSPE phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 10318 115602 - K Ubiquitination 21139048 10318 115602 - K Ubiquitination 21906983 10318 115602 - K Ubiquitination 25147182

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID TNIP1 Homo sapiens (Human) 496 "496,LKKQVEKLQAQVT" 496:21906983 NAF1 Homo sapiens (Human) 290 "290,QYIFTEKLKQDKG" 290:21906983 TNIP1 Homo sapiens (Human) 496 "496,LKKQVEKLQAQVT" 496:21906983 TNIP1 Homo sapiens (Human) 496 "496,LKKQVEKLQAQVT" 496:21906983