PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBE2E1 TRIM7 21143188 biogrid exp GP P P P P P P P P G P G GP GP P P UBE2D3 TRIM7 21143188 biogrid exp GP P P P P P P P P P P G P P G GP G P P P SIAH1 TRIM7 25416956 biogrid,intact exp GP P P P P P P P P P P P P P G P P GP GP GP P P P DES TRIM7 11916970 hprd exp G P G GP G UBE2D1 TRIM7 21143188 biogrid exp GP P P P P P P P P P P G P P G GP G P P P UBE2D2 TRIM7 21143188 biogrid exp GP P P P P P P P P P P G P P G GP G P P P HSP90AA1 TRIM7 22939624 biogrid exp GP P P P P G P G G G P VPS26B TRIM7 26496610 biogrid,intact exp G P P P P P P P P P P G P P GP G GP P P HSP90AB1 TRIM7 22939624 intact exp GP P P P P P P P P P P P P P G P P GP GP GP P P P AARSD1 TRIM7 25036637 intact exp P P P P P P P P P P P P P P P P P P HSF2 TRIM7 25036637 intact exp G G G G G P TRIM7 TRIM7 14984203 biogrid exp GP P P P P P P P P P P P P P G P P GP GP GP P P P GYG1 TRIM7 11916970,14984203, 21836163 hprd,biogrid exp, pred G P P P P P P G G GP G P GYG2 TRIM7 25402006 pred G P P P P G G P GYS1 TRIM7 25402006 pred GP P P P P P P P P P P P P P G P P GP GP GP P P P TRIM7 GABARAPL1 25402006 pred GP P P P P P P P P P P G P GP GP GP P P TRAT1 TRIM7 21836163 pred P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q7CKB3 Q9C029 two hybrid pooling approach 20711500 physical association X 2 Q9C029 Q81W18 two hybrid pooling approach 20711500 physical association X 2 Q9C029 Q9BTE6-2 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q03933 Q9C029 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q81Y62 Q9C029 two hybrid pooling approach 20711500 physical association X 2 Q8ZIK3 Q9C029 two hybrid pooling approach 20711500 physical association X 2 Q8IUQ4 Q9C029 two hybrid prey pooling approach 25416956 physical association X 2 Q8IUQ4 Q9C029 two hybrid array 25416956 physical association X 2 Q8IUQ4 Q9C029 validated two hybrid 25416956 physical association X 2 Q7CGK0 Q9C029 two hybrid pooling approach 20711500 physical association X 2 Q9C029 Q81XS6 two hybrid pooling approach 20711500 physical association X 2 Q9C029 Q8CLD8 two hybrid pooling approach 20711500 physical association X 2 Q9C029 A0A024RD80 luminescence based mammalian interactome mapping 22939624 physical association X 2 Q81RN3 Q9C029 two hybrid pooling approach 20711500 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality GYG1 TRIM7 14984203,11916970,11916970,14984203,11916970 0096,0004,0018,0018,0415 LC VPS26B TRIM7 26496610,26496610 0007,0004 HT VPS26B TRIM7 26496610,26496610 0007,0004 HT GYG1 TRIM7 14984203,11916970,11916970,14984203,11916970 0096,0004,0018,0018,0415 LC HSP90AB1 TRIM7 22939624 0729 HT DES TRIM7 11916970 0018 LC GYG1 TRIM7 14984203,11916970,11916970,14984203,11916970 0096,0004,0018,0018,0415 LC UBE2D1 TRIM7 21143188 0018 LC UBE2E1 TRIM7 21143188 0018 LC UBE2D3 TRIM7 21143188 0018 LC UBE2D2 TRIM7 21143188 0018 LC HSF2 TRIM7 25036637 0729 HT TMP_LOCUS_29 TRIM7 11916970 0018 LC SIAH1 TRIM7 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT AARSD1 TRIM7 25036637 0729 HT TRIM7 TRIM7 14984203 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9C029 P07900 TRIM7 HSP90AA1 0.126 22939624 Q9C029 P08238 TRIM7 HSP90AB1 0.126 22939624 Q9C029 Q7CGK0 TRIM7 ATOC 0.126 20711500 Q9C029 Q7CKB3 TRIM7 SGBU 0.126 20711500 Q9C029 Q81RN3 TRIM7 Q81RN3 0.126 20711500 Q9C029 Q81W18 TRIM7 DNAX 0.126 20711500 Q9C029 Q81XS6 TRIM7 Q81XS6 0.126 20711500 Q9C029 Q81Y62 TRIM7 Q81Y62 0.126 20711500 Q9C029 P07998 TRIM7 RNASE1 0.236 unassigned1304 Q9NWZ3 Q9C029 IRAK4 TRIM7 0.236 unassigned1304 Q9UI95 Q9C029 MAD2L2 TRIM7 0.236 unassigned1304 Q9Y281 Q9C029 CFL2 TRIM7 0.236 unassigned1304 Q9C029 Q96AH0 TRIM7 NABP1 0.236 unassigned1304 Q9C029 Q13671 TRIM7 RIN1 0.236 unassigned1304 Q9C029 P07315 TRIM7 CRYGC 0.236 unassigned1304 Q9C029 Q9BVE2 TRIM7 Q9BVE2 0.236 unassigned1304 Q9C029 P50895 TRIM7 BCAM 0.236 unassigned1304 Q9C029 P46976 TRIM7 GYG1 0.82 11916970,14984203 Q9C029 P29972 TRIM7 AQP1 0.236 unassigned1304 Q9UBT7 Q9C029 CTNNAL1 TRIM7 0.236 unassigned1304 Q9C029 P61019 TRIM7 RAB2A 0.236 unassigned1304 Q9C029 P52657 TRIM7 GTF2A2 0.236 unassigned1304 Q9C029 P57060 TRIM7 RWDD2B 0.236 unassigned1304 Q9C029 Q8TBZ6 TRIM7 TRMT10A 0.236 unassigned1304 Q9C029 Q5VZE5 TRIM7 NAA35 0.236 unassigned1304 Q9C029 Q8NBR0 TRIM7 TP53I13 0.236 unassigned1304 Q9UHP6 Q9C029 RTDR1 TRIM7 0.236 unassigned1304 Q9C029 Q4G0F5 TRIM7 VPS26B 0.236 26496610 Q9C029 Q6ZWV7 TRIM7 RPL35 0.236 26496610 Q9C029 Q7L8S5 TRIM7 OTUD6A 0.236 unassigned1304 Q9C029 Q8ZIK3 TRIM7 LPTD 0.126 20711500 Q9C029 Q9BTE6 TRIM7 AARSD1 0.126 25036637 Q9C029 P51668 TRIM7 UBE2D1 0.183 21143188 Q9C029 P51965 TRIM7 UBE2E1 0.183 21143188 Q9C029 P61077 TRIM7 UBE2D3 0.183 21143188 Q9C029 P62837 TRIM7 UBE2D2 0.183 21143188 Q9C029 Q03933 TRIM7 HSF2 0.126 25036637 Q9C029 Q8CLD8 TRIM7 ICMF2 0.126 20711500 Q9C029 Q8IUQ4 TRIM7 SIAH1 0.454 25416956 Q9C029 Q9C029 TRIM7 TRIM7 0.332 14984203