PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PYHIN1 PHIP 25665578 intact exp P G G G P G P P G P GP P GP G GP P P P P P G P P G NR4A1 PHIP 20195357 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TMPO PHIP 26496610 biogrid exp GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP HDAC11 23752268 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PHIP MPHOSPH8 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP DCUN1D1 21145461 biogrid exp P G G G GP G P P G P P P GP G GP G GP GP P GP GP P GP G CNTROB PHIP 26638075 biogrid,intact exp GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TMPO PHIP 26496610 intact exp PHIP STMN4 16169070 hprd,biogrid,i2d,mint,intact exp P GP G G G GP G GP GP G GP G P P GP GP GP GP G P P GP GP GP P P G CENPA PHIP 15009096 biogrid exp GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP G G GP GP G GP GP G CUL3 PHIP 25011449 biogrid exp GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G CUL7 PHIP 24711643 biogrid exp GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G IFI16 PHIP 25665578,25693804 biogrid,intact exp G G G G G GP G G GP G GP G G GP G G GP GP G G G G G G G G G G G HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J PHIP 25281560 biogrid exp P GP G G P GP P P P P P P P P P GP GP GP P G P P OBSL1 PHIP 24711643 biogrid exp GP GP G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP SIRT7 22586326 biogrid exp GP GP G G G GP G GP GP G GP G G GP G GP GP G GP G GP G GP GP GP G GP GP G TUBB4A PHIP 16169070 intact exp GP GP G G G GP G GP GP G GP G GP GP GP GP GP GP G GP P GP GP GP G GP GP G EGR1 PHIP 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G DDB1 PHIP 26344197,16949367,16964240 biogrid exp GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G RPL10 PHIP 26496610 biogrid,intact exp P P P P P P P P P P P P P P P P P P P ORC1 PHIP 26496610 biogrid,intact exp P P G G P P P P P P P P P P P P P P P P TUBB3 PHIP 16169070 hprd,biogrid,mint exp GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G SPICE1 PHIP 26638075 biogrid,intact exp GP P P P GP GP GP GP G GP P GP P G P GP GP P GP GP GP PHIP RNF2 24457600 biogrid exp P P P GP P P P P P P P P P P IRS1 PHIP 11018022, 25402006 hprd exp, ortho, pred GP GP G GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP P G CUL4B PHIP 26496610,16949367,21145461, 25402006 biogrid,intact exp, pred GP GP G G G GP G GP GP G GP G G GP G GP GP G GP G GP GP GP GP GP G GP GP G CUL4A PHIP 19295130,16949367,21145461,16964240, 25402006 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G YWHAE PHIP ortho GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP IRS2 25402006 ortho, pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP BRD8 23023127 pred P P G G P P P P P P P P P GP P P P P P GP TRPC4AP PHIP 25402006 pred GP GP G G G GP G GP GP G GP G GP G G GP GP GP GP G GP G GP G GP G GP GP G PHIP ZMYND8 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G PHIP FAF1 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G SMARCA2 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G NCK1 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G KITLG PHIP 23023127 pred G G G G G GP G G GP G GP G GP GP G GP GP G G G GP GP G GP GP G GP G G GRB14 PHIP 23023127 pred P GP P G GP GP GP G P GP P P G GP GP P P GP P GP PHIP FAF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PHIP BAIAP2 23023127 pred P P G G G GP G GP P G GP G GP GP P GP GP GP G GP GP P P P GP GP G ENPP1 PHIP 23023127 pred GP G G G GP G G G G GP G G G G G GP G GP G G G G G G G GP GP G PHIP COPS7B 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP AKAP1 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP KAT2B 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G DGKH PHIP 23023127 pred P P G GP G GP P G P G P P GP GP GP P GP P P GP GP P P G LUC7L3 PHIP 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP CLCF1 23023127 pred GP GP P G GP GP GP P GP G GP GP GP GP GP GP GP G GP P G GRB10 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PNISR PHIP 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G GP GP GP GP G GP GP G PRKCI PHIP 23023127 pred GP GP G G G GP G G GP G GP G GP G G GP GP G GP G GP GP G G GP G GP GP G PHIP DTL 25402006 pred P P G G P G P P G P GP P P P P G G G GP PHIP STMN2 23023127 pred G G G G G G G G G G G G G G PHIP SMARCC1 23023127 pred GP G G G G GP G G GP G GP G GP GP G GP GP GP GP G GP GP G G GP G GP GP G EGF PHIP 23023127 pred P P P GP P GP P P G P P GP P GP GP GP GP P P BCAR1 PHIP 23023127 pred GP GP G GP G GP GP G GP G GP GP GP GP GP GP G GP GP GP GP GP G GP GP G BRPF1 PHIP 23023127 pred GP GP G G G GP G GP G G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP CREBBP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G UBXN7 PHIP 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP ING4 23023127 pred GP GP G G G GP G GP G G GP G GP GP G GP GP GP P G GP GP GP GP GP G GP GP G PHIP AP3S1 23023127 pred GP G G G G GP G GP G G GP G GP G G G GP G G G G G GP G G G G GP G PHIP PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G BRD2 PHIP 23023127 pred G GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP G G GP GP G GP GP G SPTA1 PHIP 23023127 pred P G G P G P P P G P P P P G G GP P P GP G TLE2 PHIP 25402006 pred G GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP G GP GP G GP GP G PHIP DDB2 25402006 pred GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP G GP GP G GP GP G TAF1L PHIP 23023127 pred G P G P G G TRIM24 PHIP 23023127 pred G G G G G G G G GP G G G GP GP G GP G GP G G GP GP GP GP GP G GP GP G PHIP BAZ1B 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP DLC1 23023127 pred G G G G G GP G G GP G GP G G G G GP GP G G G G G G G GP G G GP G PHIP BRPF3 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G DCAF11 PHIP 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G HMGB1 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G COPS2 PHIP 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP BAZ1A 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G POU3F2 PHIP 23023127 pred G G G G G G G G PHIP CECR2 23023127 pred GP GP G G G GP G P GP G P G GP P G GP GP P GP G GP P GP GP GP P GP INPPL1 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G IGFBP2 PHIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G TAF1 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G BCL6 PHIP 23023127 pred G G G G G G G G G G G G G GP G G G G G G GP G G G G G G G G BRD1 PHIP 23023127 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G G GP G GNG2 PHIP 23023127 pred G G G G G GP G G GP G GP G G GP G G GP GP GP G GP G GP G G G GP GP G DLG1 PHIP 23023127 pred GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G PHIP NKX3-1 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP G HMGB2 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP UBQLN1 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PKN1 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP BRD9 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP AMBRA1 25402006 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G P G GP GP GP GP GP G GP GP G WDTC1 PHIP 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G BAG4 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G EP300 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G GIGYF1 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PBRM1 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP G GP GP GP G GP GP G BRDT PHIP 23023127 pred P P P P P P P P P P P P P P P P P P GP EPHA7 PHIP 23023127 pred P P G GP G G GP G GP P P GP GP P P G P GP GP P GP G GP STX3 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G STAT5B PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G G G GP GP GP G GP G GP GP G HOXA13 PHIP 23023127 pred G G G G PTK2B PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G P GP G G GP G GP GP G BIRC5 PHIP 23023127 pred P G G P GP GP P G GP P P GP GP GP DCAF4 PHIP 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G CNKSR3 PHIP 23023127 pred GP GP G GP G GP GP G GP G G G G GP GP GP GP G GP GP GP G GP G GP GP G PHIP VPRBP 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G SPTBN1 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G POU3F3 PHIP 23023127 pred G G G G G G BPTF PHIP 23023127 pred G GP G G G GP G G GP G GP G GP G G GP GP GP G G GP G GP G GP G GP GP G RFWD2 PHIP 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ZNF638 PHIP 25402006 pred GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G BRD4 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G INS PHIP 23023127 pred G GP G DCAF12 PHIP 25402006 pred G G G G G GP G G GP G G G GP GP G GP GP GP GP G G G GP GP GP G GP G G PHIP SKA1 23023127 pred P P P P P P P P P P P P P P P P P P P DET1 PHIP 25402006 pred G G G G G GP G G G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G SUPT3H PHIP 25402006 pred P GP G G G GP G GP P G GP G P GP G P GP GP GP G GP GP GP GP GP G GP GP G GH1 PHIP 23023127 pred G G G G G G GP GP TNKS PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G SPTAN1 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP DCAF5 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G DCAF10 PHIP 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G ZNF292 PHIP 25402006 pred G G G G G GP G G GP G GP G G GP G G GP G G G GP G G GP G G G G G IGFBP1 PHIP 23023127 pred GP G G G GP G UBE2C PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G DCAF6 PHIP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PHIP KAT2A 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP G GP GP G GP GP G PHIP TRIM33 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G TERF1 PHIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PHIP DDA1 25402006 pred GP GP G G G GP G GP GP G GP G GP G GP GP GP P G GP GP GP GP GP G GP GP G MTOR PHIP 23023127 pred G GP G G G GP G G G G G G GP G G G GP G G G G GP G G G G GP G G SMARCA4 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G DCAF8 PHIP 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PHIP DDIT4 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TRIM66 PHIP 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G PHIP SPTBN4 23023127 pred P G GP G P GP G P P P GP P G P P GP P P GP ERCC8 PHIP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8WWQ0 anti tag coimmunoprecipitation 23752268 association C 124 Q9H169 Q8WWQ0 two hybrid pooling approach 16169070 physical association X 2 Q81MY7 Q8WWQ0 two hybrid pooling approach 20711500 physical association X 2 Q8WWQ0 P04350 two hybrid pooling approach 16169070 physical association X 2 Q8WWQ0 A0A024R126 display technology 20195357 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B RNF2 PHIP MI:0004(affinity chromatography technology) 24457600 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_306984 bait prey TUBB4A PHIP MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_156658 bait prey SUMO2 PHIP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19471022,21693764 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_165676|BIOGRID_183209 bait|bait prey|prey UBC PHIP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18781797,21139048,21890473,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_167312|BIOGRID_174017|BIOGRID_269379|BIOGRID_162234 bait|bait|bait|bait prey|prey|prey|prey IRS1 PHIP MI:0493(in vivo) 11018022 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_36382 - - PHIP TUBB3 MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_35728|MINT_64756 prey|prey bait|bait NR4A1 PHIP MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104731 bait prey CUL4B PHIP MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_203254 bait prey PHIP SIRT7 MI:0004(affinity chromatography technology) 22586326 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_189222 prey bait CUL4A PHIP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16964240,19295130,21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_221324|BIOGRID_122525|BIOGRID_202933 bait|bait|bait prey|prey|prey HDAC11 PHIP MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 23752268 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_280814|UniProt_131422 bait|bait prey|prey PHIP STMN4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0468(hprd)|(intact) MINT_65125|MINT_36035|BIOGRID_94004|HPRD_29905|UniProt_156578 prey|prey|prey|-|prey bait|bait|bait|-|bait TUBB3 PHIP MI:0018(two hybrid)|MI:0492(in vitro) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_94083|HPRD_29122 bait|- prey|- CENPA PHIP MI:0401(biochemical) 15009096 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association) (biogrid) BIOGRID_135974 bait prey DDB1 PHIP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16949367,16964240 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_122498|BIOGRID_122856 bait|bait prey|prey DCUN1D1 PHIP MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_206024 bait prey

PPI - HINT Gene A Gene B PMID Method Quality EGR1 PHIP 26496610,26496610 0007,0004 HT RPL10 PHIP 26496610,26496610 0007,0004 HT TMPO PHIP 26496610 0007 HT ORC1 PHIP 26496610 0007 HT CUL4A PHIP 16949367,16964240,21145461,19295130 0004,0004,0004,0004 LC,HT CUL4B PHIP 26496610,16949367,21145461,26496610 0007,0004,0004,0004 HT,LC DDB1 PHIP 16949367,16964240,26344197 0004,0004,0401 LC,HT IFI16 PHIP 25665578,25693804 0007,0004 LC Q59G12 PHIP 26496610 0004 HT SPICE1 PHIP 26638075,26638075 1314,1313 HT CNTROB PHIP 26638075,26638075 1314,1313 HT PHIP ORC1L 26496610 0004 HT PHIP DCUN1D1 21145461 0004 HT PHIP MPHOSPH8 26496610,26496610 0007,0004 HT EGR1 PHIP 26496610,26496610 0007,0004 HT RPL10 PHIP 26496610,26496610 0007,0004 HT TMPO PHIP 26496610 0007 HT ORC1 PHIP 26496610 0007 HT CUL4A PHIP 21145461 0004 HT CUL4B PHIP 26496610,21145461,26496610 0007,0004,0004 HT DDB1 PHIP 26344197 0401 HT Q59G12 PHIP 26496610 0004 HT SPICE1 PHIP 26638075,26638075 1314,1313 HT CNTROB PHIP 26638075,26638075 1314,1313 HT PHIP ORC1L 26496610 0004 HT PHIP DCUN1D1 21145461 0004 HT PHIP MPHOSPH8 26496610,26496610 0007,0004 HT CUL4A PHIP 16949367,16964240,19295130 0004,0004,0004 LC CUL4B PHIP 16949367 0004 LC DDB1 PHIP 16949367,16964240 0004,0004 LC IFI16 PHIP 25665578,25693804 0007,0004 LC TUBB4A PHIP 16169070 0398 HT NR4A1 PHIP 20195357 0034 LC IRS1 PHIP 11018022 0018 LC CENPA PHIP 15009096 0401 LC TUBB3 PHIP 16169070 0018 HT DDB1 PHIP 26344197 0401 LC Q53G92 PHIP 16169070 0018 HT PHIP STMN4 16169070,16169070 0018,0398 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8WWQ0 Q8N137 PHIP CNTROB 0.126 26638075 Q9NRC8 Q8WWQ0 SIRT7 PHIP 0.126 22586326 Q8WWQ0 O75147 PHIP OBSL1 0.126 24711643 Q8WWQ0 Q6K0P9 PHIP PYHIN1 0.126 25665578 Q8WWQ0 O94888 PHIP UBXN7 0.126 26389662 Q9QWF0 Q8WWQ0 CHAF1A PHIP 0.236 26496610 Q8WWQ0 Q8N0Z3 PHIP SPICE1 0.236 26638075 Q8WWQ0 Q16531 PHIP DDB1 0.386 16964240,16949367,26344197 Q96DB2 Q8WWQ0 HDAC11 PHIP 0.236 23752268 Q8WWQ0 Q16666 PHIP IFI16 0.236 25665578,25693804 Q8WWQ0 P83917 PHIP CBX1 0.236 26496610 Q8WWQ0 Q3TCH7 PHIP CUL4A 0.236 26496610 Q8WWQ0 Q61687 PHIP ATRX 0.236 26496610 Q8WWQ0 A2AHJ4 PHIP BRWD3 0.236 26496610 Q8WWQ0 P60229 PHIP EIF3E 0.236 26496610 Q8WWQ0 Q13619 PHIP CUL4A 0.416 16964240,21145461,16949367,19295130 Q8WWQ0 P04350 PHIP TUBB4A 0.126 16169070 Q8WWQ0 P22736 PHIP NR4A1 0.126 20195357 Q9H169 Q8WWQ0 STMN4 PHIP 0.286 16169070 Q8WWQ0 Q13620 PHIP CUL4B 0.332 26496610,21145461,16949367 Q8WWQ0 Q81MY7 PHIP TKT1 0.126 20711500 Q96GG9 Q8WWQ0 DCUN1D1 PHIP 0.126 21145461 Q99496 Q8WWQ0 RNF2 PHIP 0.126 24457600 Q99549 Q8WWQ0 MPHOSPH8 PHIP 0.126 26496610 Q8WWQ0 P27635 PHIP RPL10 0.126 26496610 Q8WWQ0 Q13618 PHIP CUL3 0.21 25011449 Q8WWQ0 P18146 PHIP EGR1 0.126 26496610 Q8WWQ0 P49450 PHIP CENPA 0.21 15009096 Q8WWQ0 P42167 PHIP TMPO 0.126 26496610 Q8WWQ0 Q13509 PHIP TUBB3 0.183 16169070 Q8WWQ0 Q13415 PHIP ORC1 0.126 26496610 Q8WWQ0 P68431 PHIP HIST1H3J 0.126 25281560

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 OBSL1 PHIP MI:0045 experimental interaction detection MI:0461 interaction database UBXN7 PHIP MI:0045 experimental interaction detection MI:0461 interaction database TUBB4A PHIP MI:0045 experimental interaction detection MI:0461 interaction database UBC PHIP MI:0045 experimental interaction detection MI:0461 interaction database EGR1 PHIP MI:0045 experimental interaction detection MI:0461 interaction database NR4A1 PHIP MI:0045 experimental interaction detection MI:0461 interaction database RPL10 PHIP MI:0045 experimental interaction detection MI:0461 interaction database IRS1 PHIP MI:0362 inference MI:0461 interaction database TMPO PHIP MI:0045 experimental interaction detection MI:0461 interaction database TMPO PHIP MI:0045 experimental interaction detection MI:0461 interaction database ATRX PHIP MI:0362 inference MI:0461 interaction database CENPA PHIP MI:0045 experimental interaction detection MI:0461 interaction database SUMO3 PHIP MI:0045 experimental interaction detection MI:0461 interaction database EIF3E PHIP MI:0362 inference MI:0461 interaction database SUMO2 PHIP MI:0045 experimental interaction detection MI:0461 interaction database HIST1H3A PHIP MI:0045 experimental interaction detection MI:0461 interaction database CBX1 PHIP MI:0362 inference MI:0461 interaction database CHAF1A PHIP MI:0362 inference MI:0461 interaction database ORC1 PHIP MI:0045 experimental interaction detection MI:0461 interaction database TUBB3 PHIP MI:0045 experimental interaction detection MI:0461 interaction database CUL3 PHIP MI:0045 experimental interaction detection MI:0461 interaction database CUL4A PHIP MI:0045 experimental interaction detection MI:0461 interaction database CUL4B PHIP MI:0045 experimental interaction detection MI:0461 interaction database CUL7 PHIP MI:0045 experimental interaction detection MI:0461 interaction database DDB1 PHIP MI:0045 experimental interaction detection MI:0461 interaction database IFI16 PHIP MI:0045 experimental interaction detection MI:0461 interaction database PYHIN1 PHIP MI:0045 experimental interaction detection MI:0461 interaction database BRWD3 PHIP MI:0362 inference MI:0461 interaction database SPICE1 PHIP MI:0045 experimental interaction detection MI:0461 interaction database CNTROB PHIP MI:0045 experimental interaction detection MI:0461 interaction database PHIP HDAC11 MI:0045 experimental interaction detection MI:0461 interaction database PHIP DCUN1D1 MI:0045 experimental interaction detection MI:0461 interaction database PHIP RNF2 MI:0045 experimental interaction detection MI:0461 interaction database PHIP MPHOSPH8 MI:0045 experimental interaction detection MI:0461 interaction database PHIP STMN4 MI:0045 experimental interaction detection MI:0461 interaction database PHIP SIRT7 MI:0045 experimental interaction detection MI:0461 interaction database