Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 9 132400070 132400070 + Nonstop_Mutation SNP C C G TCGA-XF-AAMG-01A-11D-A42E-08 TCGA-XF-AAMG-10A-01D-A42H-08 g.chr9:132400070C>G c.1265G>C c.(1264-1266)tGa>tCa p.*422S BLCA 9 132400323 132400323 + Missense_Mutation SNP G G C TCGA-MV-A51V-01A-11D-A26M-08 TCGA-MV-A51V-10A-01D-A26K-08 g.chr9:132400323G>C c.1012C>G c.(1012-1014)Cag>Gag p.Q338E BLCA 9 132404198 132404198 + Silent SNP G G T TCGA-FD-A62P-01A-32D-A30E-08 TCGA-FD-A62P-10A-01D-A30H-08 g.chr9:132404198G>T c.81C>A c.(79-81)atC>atA p.I27I BRCA 9 132402823 132402823 + Missense_Mutation SNP C C T TCGA-BH-A18P-01A-11D-A12B-09 TCGA-BH-A18P-11A-43D-A12B-09 g.chr9:132402823C>T c.292G>A c.(292-294)Gaa>Aaa p.E98K BRCA 9 132404204 132404204 + Silent SNP C C A TCGA-AO-A0J2-01A-11W-A050-09 TCGA-AO-A0J2-10A-01W-A055-09 g.chr9:132404204C>A c.75G>T c.(73-75)ctG>ctT p.L25L COAD 9 132400185 132400185 + Silent SNP G G T TCGA-G4-6586-01A-11D-1771-10 TCGA-G4-6586-10A-01D-1771-10 g.chr9:132400185G>T c.1150C>A c.(1150-1152)Cgg>Agg p.R384R COAD 9 132400271 132400271 + Missense_Mutation SNP G G A TCGA-AA-3864-01A-01W-0995-10 TCGA-AA-3864-10A-01W-0995-10 g.chr9:132400271G>A c.1064C>T c.(1063-1065)gCg>gTg p.A355V COAD 9 132400453 132400453 + Silent SNP C C T TCGA-D5-6540-01A-11D-1719-10 TCGA-D5-6540-10A-01D-1719-10 g.chr9:132400453C>T c.882G>A c.(880-882)gcG>gcA p.A294A COAD 9 132400869 132400869 + Missense_Mutation SNP C C T TCGA-AA-3864-01A-01W-0995-10 TCGA-AA-3864-10A-01W-0995-10 g.chr9:132400869C>T c.581G>A c.(580-582)cGt>cAt p.R194H COADREAD 9 132400185 132400185 + Silent SNP G G T TCGA-G4-6586-01A-11D-1771-10 TCGA-G4-6586-10A-01D-1771-10 g.chr9:132400185G>T c.1150C>A c.(1150-1152)Cgg>Agg p.R384R COADREAD 9 132400271 132400271 + Missense_Mutation SNP G G A TCGA-AA-3864-01A-01W-0995-10 TCGA-AA-3864-10A-01W-0995-10 g.chr9:132400271G>A c.1064C>T c.(1063-1065)gCg>gTg p.A355V COADREAD 9 132400297 132400297 + Silent SNP G G A TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr9:132400297G>A c.1038C>T c.(1036-1038)ttC>ttT p.F346F COADREAD 9 132400453 132400453 + Silent SNP C C T TCGA-D5-6540-01A-11D-1719-10 TCGA-D5-6540-10A-01D-1719-10 g.chr9:132400453C>T c.882G>A c.(880-882)gcG>gcA p.A294A COADREAD 9 132400869 132400869 + Missense_Mutation SNP C C T TCGA-AA-3864-01A-01W-0995-10 TCGA-AA-3864-10A-01W-0995-10 g.chr9:132400869C>T c.581G>A c.(580-582)cGt>cAt p.R194H DLBC 9 132401753 132401753 + Silent SNP G G A TCGA-GR-7353-01A-11D-2210-10 TCGA-GR-7353-10A-01D-2210-10 g.chr9:132401753G>A c.330C>T c.(328-330)gcC>gcT p.A110A ESCA 9 132400455 132400455 + Missense_Mutation SNP C C A TCGA-L5-A891-01A-11D-A36J-09 TCGA-L5-A891-11A-21D-A36M-09 g.chr9:132400455C>A c.880G>T c.(880-882)Gcg>Tcg p.A294S ESCA 9 132400502 132400502 + Missense_Mutation SNP C C T TCGA-2H-A9GK-01A-11D-A37C-09 TCGA-2H-A9GK-11A-11D-A37F-09 g.chr9:132400502C>T c.833G>A c.(832-834)cGc>cAc p.R278H ESCA 9 132400710 132400710 + Missense_Mutation SNP C C A TCGA-R6-A6Y0-01B-11D-A33E-09 TCGA-R6-A6Y0-10A-01D-A33H-09 g.chr9:132400710C>A c.625G>T c.(625-627)Gat>Tat p.D209Y ESCA 9 132400881 132400881 + Missense_Mutation SNP G G T TCGA-IG-A97H-01A-11D-A387-09 TCGA-IG-A97H-10A-01D-A38A-09 g.chr9:132400881G>T c.569C>A c.(568-570)aCt>aAt p.T190N GBMLGG 9 132401579 132401580 + Frame_Shift_Del DEL CT CT - TCGA-HT-7616-01A-11D-2253-08 TCGA-HT-7616-10A-01D-2253-08 g.chr9:132401579_132401580delCT c.412_413delAG c.(412-414)agtfs p.S139fs GBMLGG 9 132404200 132404200 + Missense_Mutation SNP T T C TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr9:132404200T>C c.79A>G c.(79-81)Atc>Gtc p.I27V HNSC 9 132400134 132400134 + Missense_Mutation SNP G G C TCGA-4P-AA8J-01A-11D-A391-08 TCGA-4P-AA8J-10A-01D-A394-08 g.chr9:132400134G>C c.1201C>G c.(1201-1203)Ctg>Gtg p.L401V HNSC 9 132400246 132400246 + Silent SNP G G A TCGA-CV-A6K1-01A-11D-A31L-08 TCGA-CV-A6K1-10A-01D-A31J-08 g.chr9:132400246G>A c.1089C>T c.(1087-1089)ttC>ttT p.F363F HNSC 9 132401583 132401583 + Missense_Mutation SNP C C T TCGA-CV-5442-01A-01D-1512-08 TCGA-CV-5442-11A-01D-1512-08 g.chr9:132401583C>T c.409G>A c.(409-411)Gag>Aag p.E137K KIPAN 9 132400146 132400146 + Nonsense_Mutation SNP T T A TCGA-B1-A656-01A-11D-A31X-10 TCGA-B1-A656-10A-01D-A31X-10 g.chr9:132400146T>A c.1189A>T c.(1189-1191)Aaa>Taa p.K397* KIPAN 9 132401522 132401522 + Missense_Mutation SNP A A G TCGA-B0-5095-01A-01D-1421-08 TCGA-B0-5095-11A-01D-1421-08 g.chr9:132401522A>G c.470T>C c.(469-471)cTc>cCc p.L157P KIRC 9 132401522 132401522 + Missense_Mutation SNP A A G TCGA-B0-5095-01A-01D-1421-08 TCGA-B0-5095-11A-01D-1421-08 g.chr9:132401522A>G c.470T>C c.(469-471)cTc>cCc p.L157P KIRP 9 132400146 132400146 + Nonsense_Mutation SNP T T A TCGA-B1-A656-01A-11D-A31X-10 TCGA-B1-A656-10A-01D-A31X-10 g.chr9:132400146T>A c.1189A>T c.(1189-1191)Aaa>Taa p.K397* LGG 9 132401579 132401580 + Frame_Shift_Del DEL CT CT - TCGA-HT-7616-01A-11D-2253-08 TCGA-HT-7616-10A-01D-2253-08 g.chr9:132401579_132401580delCT c.412_413delAG c.(412-414)agtfs p.S139fs LGG 9 132404200 132404200 + Missense_Mutation SNP T T C TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr9:132404200T>C c.79A>G c.(79-81)Atc>Gtc p.I27V LIHC 9 132400301 132400301 + Missense_Mutation SNP T T G TCGA-DD-A3A2-01A-11D-A20W-10 TCGA-DD-A3A2-11A-11D-A20W-10 g.chr9:132400301T>G c.1034A>C c.(1033-1035)aAc>aCc p.N345T LUAD 9 132400147 132400147 + Silent SNP G G C TCGA-05-4382-01A-01D-1931-08 TCGA-05-4382-10A-01D-1265-08 g.chr9:132400147G>C c.1188C>G c.(1186-1188)gtC>gtG p.V396V LUAD 9 132400455 132400455 + Missense_Mutation SNP C C G TCGA-44-A47A-01A-21D-A24D-08 TCGA-44-A47A-10A-01D-A24F-08 g.chr9:132400455C>G c.880G>C c.(880-882)Gcg>Ccg p.A294P LUAD 9 132400638 132400638 + Frame_Shift_Del DEL G G - TCGA-95-A4VK-01A-11D-A25L-08 TCGA-95-A4VK-10A-01D-A25L-08 g.chr9:132400638delG c.697delC c.(697-699)cagfs p.Q233fs LUAD 9 132402830 132402830 + Silent SNP G G A TCGA-67-6215-01A-11D-1753-08 TCGA-67-6215-10A-01D-1753-08 g.chr9:132402830G>A c.285C>T c.(283-285)ctC>ctT p.L95L LUAD 9 132404236 132404236 + Missense_Mutation SNP G G T TCGA-73-4670-01A-01D-1265-08 TCGA-73-4670-11A-01D-1265-08 g.chr9:132404236G>T c.43C>A c.(43-45)Cag>Aag p.Q15K LUSC 9 132400573 132400573 + Missense_Mutation SNP G G C TCGA-66-2742-01A-01D-0983-08 TCGA-66-2742-11A-01D-0983-08 g.chr9:132400573G>C c.762C>G c.(760-762)agC>agG p.S254R OV 9 132400169 132400169 + Missense_Mutation SNP G G A TCGA-61-1722-01A-01D-1556-09 TCGA-61-1722-11A-01W-0639-09 g.chr9:132400169G>A c.1166C>T c.(1165-1167)cCg>cTg p.P389L PRAD 9 132400168 132400168 + Silent SNP C C T TCGA-EJ-5525-01A-01D-1576-08 TCGA-EJ-5525-10A-01D-1577-08 g.chr9:132400168C>T c.1167G>A c.(1165-1167)ccG>ccA p.P389P PRAD 9 132400656 132400656 + Missense_Mutation SNP C C A TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr9:132400656C>A c.679G>T c.(679-681)Ggg>Tgg p.G227W PRAD 9 132401543 132401543 + Missense_Mutation SNP C C T TCGA-V1-A8WL-01A-11D-A377-08 TCGA-V1-A8WL-10A-01D-A37A-08 g.chr9:132401543C>T c.449G>A c.(448-450)cGc>cAc p.R150H READ 9 132400297 132400297 + Silent SNP G G A TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr9:132400297G>A c.1038C>T c.(1036-1038)ttC>ttT p.F346F SKCM 9 132401685 132401685 + Missense_Mutation SNP T T C TCGA-EE-A3AB-06A-11D-A196-08 TCGA-EE-A3AB-10A-01D-A198-08 g.chr9:132401685T>C c.398A>G c.(397-399)gAc>gGc p.D133G SKCM 9 132402973 132402973 + Nonsense_Mutation SNP G G A TCGA-EE-A29L-06A-12D-A196-08 TCGA-EE-A29L-10A-01D-A198-08 g.chr9:132402973G>A c.142C>T c.(142-144)Cga>Tga p.R48*

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 9 132400070 132400070 single base substitution C G 3_prime_UTR_variant BLCA-CN 9 132400070 132400070 single base substitution C G stop_lost *343S 1028G>C BLCA-CN 9 132400070 132400070 single base substitution C G stop_lost *422S 1265G>C BLCA-CN 9 132400354 132400354 single base substitution C G 3_prime_UTR_variant BLCA-CN 9 132400354 132400354 single base substitution C G missense_variant E248D 744G>C BLCA-CN 9 132400354 132400354 single base substitution C G missense_variant E327D 981G>C BLCA-CN 9 132400575 132400575 single base substitution T C 3_prime_UTR_variant BLCA-CN 9 132400575 132400575 single base substitution T C missense_variant S175G 523A>G BLCA-CN 9 132400575 132400575 single base substitution T C missense_variant S254G 760A>G BLCA-CN 9 132400668 132400668 single base substitution C T missense_variant E144K 430G>A BLCA-CN 9 132400668 132400668 single base substitution C T missense_variant E223K 667G>A BLCA-CN 9 132400668 132400668 single base substitution C T synonymous_variant V186V 558G>A BLCA-CN 9 132400859 132400859 single base substitution C T stop_gained W161* 482G>A BLCA-CN 9 132400859 132400859 single base substitution C T synonymous_variant L118L 354G>A BLCA-CN 9 132400859 132400859 single base substitution C T synonymous_variant L197L 591G>A BOCA-FR 9 132395288 132395288 single base substitution G C downstream_gene_variant BRCA-EU 9 132395064 132395064 single base substitution G A downstream_gene_variant BRCA-EU 9 132395280 132395282 deletion of <=200bp GAG - downstream_gene_variant BRCA-EU 9 132396376 132396376 single base substitution G T downstream_gene_variant BRCA-EU 9 132398713 132398713 single base substitution T C downstream_gene_variant BRCA-EU 9 132399084 132399084 single base substitution C A downstream_gene_variant BRCA-EU 9 132399210 132399210 single base substitution A T 3_prime_UTR_variant BRCA-EU 9 132399210 132399210 single base substitution A T downstream_gene_variant BRCA-EU 9 132400168 132400168 single base substitution C T 3_prime_UTR_variant BRCA-EU 9 132400168 132400168 single base substitution C T synonymous_variant P310P 930G>A BRCA-EU 9 132400168 132400168 single base substitution C T synonymous_variant P389P 1167G>A BRCA-EU 9 132402607 132402607 single base substitution C G intron_variant BRCA-EU 9 132403183 132403183 single base substitution G C intron_variant BRCA-EU 9 132404511 132404511 single base substitution C A upstream_gene_variant BRCA-EU 9 132405208 132405208 single base substitution C T upstream_gene_variant BRCA-EU 9 132405911 132405911 single base substitution C T upstream_gene_variant BRCA-EU 9 132407674 132407674 single base substitution G T upstream_gene_variant BRCA-EU 9 132408451 132408451 single base substitution G A upstream_gene_variant BRCA-EU 9 132408811 132408811 single base substitution G T upstream_gene_variant BRCA-EU 9 132409100 132409100 single base substitution G A upstream_gene_variant BRCA-EU 9 132409311 132409311 single base substitution A C upstream_gene_variant BRCA-FR 9 132403183 132403183 single base substitution G C intron_variant BRCA-FR 9 132408451 132408451 single base substitution G A upstream_gene_variant BRCA-UK 9 132394987 132394987 deletion of <=200bp C - downstream_gene_variant BRCA-US 9 132395102 132395102 single base substitution C T downstream_gene_variant BRCA-US 9 132395277 132395277 single base substitution C A downstream_gene_variant BRCA-US 9 132397566 132397566 single base substitution C G downstream_gene_variant BRCA-US 9 132397668 132397668 single base substitution C T downstream_gene_variant BRCA-US 9 132402823 132402823 single base substitution C T intron_variant BRCA-US 9 132402823 132402823 single base substitution C T missense_variant E98K 292G>A BRCA-US 9 132404204 132404204 single base substitution C A missense_variant W7L 20G>T BRCA-US 9 132404204 132404204 single base substitution C A synonymous_variant L25L 75G>T BTCA-JP 9 132397728 132397733 deletion of <=200bp CTTTGC - downstream_gene_variant BTCA-JP 9 132401063 132401063 single base substitution C G intron_variant CESC-US 9 132395004 132395004 single base substitution G C downstream_gene_variant CESC-US 9 132395141 132395141 single base substitution G C downstream_gene_variant CESC-US 9 132397623 132397623 single base substitution C T downstream_gene_variant CLLE-ES 9 132405027 132405027 single base substitution T G upstream_gene_variant COAD-US 9 132396561 132396561 single base substitution G A downstream_gene_variant COAD-US 9 132397680 132397680 single base substitution C T downstream_gene_variant COAD-US 9 132397719 132397719 single base substitution T G downstream_gene_variant COAD-US 9 132400185 132400185 single base substitution G T 3_prime_UTR_variant COAD-US 9 132400185 132400185 single base substitution G T synonymous_variant R305R 913C>A COAD-US 9 132400185 132400185 single base substitution G T synonymous_variant R384R 1150C>A COAD-US 9 132400453 132400453 single base substitution C T 3_prime_UTR_variant COAD-US 9 132400453 132400453 single base substitution C T synonymous_variant A215A 645G>A COAD-US 9 132400453 132400453 single base substitution C T synonymous_variant A294A 882G>A COCA-CN 9 132396558 132396558 single base substitution G A downstream_gene_variant COCA-CN 9 132400297 132400297 single base substitution G A 3_prime_UTR_variant COCA-CN 9 132400297 132400297 single base substitution G A synonymous_variant F267F 801C>T COCA-CN 9 132400297 132400297 single base substitution G A synonymous_variant F346F 1038C>T COCA-CN 9 132400454 132400454 single base substitution G A 3_prime_UTR_variant COCA-CN 9 132400454 132400454 single base substitution G A missense_variant A215V 644C>T COCA-CN 9 132400454 132400454 single base substitution G A missense_variant A294V 881C>T COCA-CN 9 132400806 132400806 single base substitution G A intron_variant COCA-CN 9 132400968 132400968 single base substitution A G intron_variant COCA-CN 9 132401824 132401824 single base substitution G A intron_variant COCA-CN 9 132402870 132402870 single base substitution G A intron_variant COCA-CN 9 132402870 132402870 single base substitution G A missense_variant T82M 245C>T COCA-CN 9 132404257 132404257 single base substitution G T 5_prime_UTR_variant COCA-CN 9 132404257 132404257 single base substitution G T synonymous_variant R8R 22C>A ESAD-UK 9 132397159 132397159 single base substitution A G downstream_gene_variant ESAD-UK 9 132397564 132397564 single base substitution A C downstream_gene_variant ESAD-UK 9 132399589 132399589 single base substitution C A 3_prime_UTR_variant ESAD-UK 9 132399589 132399589 single base substitution C A downstream_gene_variant ESAD-UK 9 132399911 132399911 single base substitution A G 3_prime_UTR_variant ESAD-UK 9 132399911 132399911 single base substitution A G downstream_gene_variant ESAD-UK 9 132402092 132402092 single base substitution G A intron_variant ESAD-UK 9 132405353 132405353 single base substitution C T upstream_gene_variant ESAD-UK 9 132407918 132407918 single base substitution G A upstream_gene_variant ESCA-CN 9 132396655 132396655 single base substitution A G downstream_gene_variant GBM-US 9 132394975 132394975 single base substitution G A downstream_gene_variant KIRC-US 9 132401522 132401522 single base substitution A G intron_variant KIRC-US 9 132401522 132401522 single base substitution A G missense_variant L157P 470T>C KIRC-US 9 132401522 132401522 single base substitution A G missense_variant L78P 233T>C KIRP-US 9 132400146 132400146 single base substitution T A 3_prime_UTR_variant KIRP-US 9 132400146 132400146 single base substitution T A stop_gained K318* 952A>T KIRP-US 9 132400146 132400146 single base substitution T A stop_gained K397* 1189A>T LAML-KR 9 132396655 132396655 single base substitution A G downstream_gene_variant LGG-US 9 132401579 132401580 deletion of <=200bp CT - frameshift_variant S138 LGG-US 9 132401579 132401580 deletion of <=200bp CT - frameshift_variant S59 LGG-US 9 132401579 132401580 deletion of <=200bp CT - intron_variant LICA-FR 9 132396583 132396583 single base substitution T C downstream_gene_variant LICA-FR 9 132399210 132399210 single base substitution A G 3_prime_UTR_variant LICA-FR 9 132399210 132399210 single base substitution A G downstream_gene_variant LIHC-US 9 132400301 132400301 single base substitution T G 3_prime_UTR_variant LIHC-US 9 132400301 132400301 single base substitution T G missense_variant N266T 797A>C LIHC-US 9 132400301 132400301 single base substitution T G missense_variant N345T 1034A>C LIHC-US 9 132400355 132400355 single base substitution T C 3_prime_UTR_variant LIHC-US 9 132400355 132400355 single base substitution T C missense_variant E248G 743A>G LIHC-US 9 132400355 132400355 single base substitution T C missense_variant E327G 980A>G LINC-JP 9 132397502 132397502 single base substitution A T downstream_gene_variant LINC-JP 9 132401863 132401863 single base substitution C T intron_variant LINC-JP 9 132404471 132404471 single base substitution G A upstream_gene_variant LIRI-JP 9 132399751 132399751 single base substitution C G 3_prime_UTR_variant LIRI-JP 9 132399751 132399751 single base substitution C G downstream_gene_variant LIRI-JP 9 132399870 132399870 single base substitution A T 3_prime_UTR_variant LIRI-JP 9 132399870 132399870 single base substitution A T downstream_gene_variant LIRI-JP 9 132402549 132402549 deletion of <=200bp T - intron_variant LIRI-JP 9 132407581 132407581 single base substitution G A upstream_gene_variant LUSC-KR 9 132397252 132397252 single base substitution G A downstream_gene_variant LUSC-KR 9 132398565 132398565 single base substitution G A downstream_gene_variant LUSC-KR 9 132401100 132401100 single base substitution C A intron_variant LUSC-KR 9 132404208 132404208 single base substitution G C missense_variant P6A 16C>G LUSC-KR 9 132404208 132404208 single base substitution G C missense_variant S24C 71C>G LUSC-KR 9 132407772 132407772 single base substitution C T upstream_gene_variant LUSC-US 9 132400573 132400573 single base substitution G C 3_prime_UTR_variant LUSC-US 9 132400573 132400573 single base substitution G C missense_variant S175R 525C>G LUSC-US 9 132400573 132400573 single base substitution G C missense_variant S254R 762C>G MALY-DE 9 132399502 132399502 single base substitution G T 3_prime_UTR_variant MALY-DE 9 132399502 132399502 single base substitution G T downstream_gene_variant MALY-DE 9 132401978 132401978 single base substitution G A intron_variant MELA-AU 9 132395165 132395165 single base substitution C T downstream_gene_variant MELA-AU 9 132397675 132397675 single base substitution C T downstream_gene_variant MELA-AU 9 132400386 132400386 single base substitution C T 3_prime_UTR_variant MELA-AU 9 132400386 132400386 single base substitution C T missense_variant E238K 712G>A MELA-AU 9 132400386 132400386 single base substitution C T missense_variant E317K 949G>A MELA-AU 9 132401685 132401685 single base substitution T C missense_variant D133G 398A>G MELA-AU 9 132401685 132401685 single base substitution T C missense_variant D54G 161A>G MELA-AU 9 132402495 132402495 single base substitution T C intron_variant MELA-AU 9 132402537 132402537 single base substitution T C intron_variant MELA-AU 9 132402805 132402806 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 9 132402973 132402973 single base substitution G A intron_variant MELA-AU 9 132402973 132402973 single base substitution G A stop_gained R48* 142C>T MELA-AU 9 132404459 132404459 single base substitution C T upstream_gene_variant MELA-AU 9 132404796 132404796 single base substitution C T upstream_gene_variant MELA-AU 9 132404797 132404797 single base substitution C T upstream_gene_variant MELA-AU 9 132404951 132404952 multiple base substitution (>=2bp and <=200bp) GG TC upstream_gene_variant MELA-AU 9 132405292 132405292 single base substitution G A upstream_gene_variant MELA-AU 9 132405600 132405600 single base substitution C T upstream_gene_variant MELA-AU 9 132405877 132405877 single base substitution C T upstream_gene_variant MELA-AU 9 132405899 132405899 single base substitution G A upstream_gene_variant MELA-AU 9 132406047 132406047 single base substitution G A upstream_gene_variant MELA-AU 9 132406414 132406414 single base substitution T G upstream_gene_variant MELA-AU 9 132406499 132406499 single base substitution C T upstream_gene_variant MELA-AU 9 132406613 132406613 single base substitution G A upstream_gene_variant MELA-AU 9 132407541 132407541 single base substitution C T upstream_gene_variant MELA-AU 9 132407621 132407621 single base substitution C T upstream_gene_variant MELA-AU 9 132407819 132407819 single base substitution T A upstream_gene_variant MELA-AU 9 132408078 132408078 single base substitution C T upstream_gene_variant MELA-AU 9 132408372 132408372 single base substitution G A upstream_gene_variant MELA-AU 9 132408825 132408825 single base substitution C T upstream_gene_variant MELA-AU 9 132408875 132408875 single base substitution G A upstream_gene_variant MELA-AU 9 132408967 132408967 single base substitution C T upstream_gene_variant MELA-AU 9 132409040 132409040 single base substitution C T upstream_gene_variant MELA-AU 9 132409059 132409059 single base substitution G A upstream_gene_variant MELA-AU 9 132409224 132409224 single base substitution G A upstream_gene_variant MELA-AU 9 132409430 132409430 single base substitution T C upstream_gene_variant ORCA-IN 9 132396547 132396547 single base substitution C T downstream_gene_variant ORCA-IN 9 132400570 132400570 single base substitution C A 3_prime_UTR_variant ORCA-IN 9 132400570 132400570 single base substitution C A missense_variant E176D 528G>T ORCA-IN 9 132400570 132400570 single base substitution C A missense_variant E255D 765G>T ORCA-IN 9 132401762 132401762 single base substitution C A missense_variant L107F 321G>T ORCA-IN 9 132401762 132401762 single base substitution C A missense_variant L28F 84G>T ORCA-IN 9 132403000 132403000 single base substitution G T intron_variant ORCA-IN 9 132403000 132403000 single base substitution G T missense_variant P39T 115C>A OV-AU 9 132396550 132396550 single base substitution A C downstream_gene_variant OV-AU 9 132398863 132398863 single base substitution C G downstream_gene_variant OV-AU 9 132399265 132399265 single base substitution C G 3_prime_UTR_variant OV-AU 9 132399265 132399265 single base substitution C G downstream_gene_variant OV-AU 9 132399867 132399867 single base substitution G T 3_prime_UTR_variant OV-AU 9 132399867 132399867 single base substitution G T downstream_gene_variant OV-AU 9 132408480 132408480 single base substitution T A upstream_gene_variant PACA-AU 9 132394470 132394470 single base substitution G A downstream_gene_variant PACA-AU 9 132403877 132403877 deletion of <=200bp G - intron_variant PACA-AU 9 132407718 132407718 single base substitution C T upstream_gene_variant PACA-CA 9 132396083 132396083 single base substitution A G downstream_gene_variant PACA-CA 9 132401583 132401583 single base substitution C T intron_variant PACA-CA 9 132401583 132401583 single base substitution C T missense_variant E137K 409G>A PACA-CA 9 132401583 132401583 single base substitution C T missense_variant E58K 172G>A PACA-CA 9 132406348 132406348 single base substitution G A upstream_gene_variant PACA-CA 9 132406372 132406372 single base substitution C G upstream_gene_variant PACA-CA 9 132407099 132407099 single base substitution C T upstream_gene_variant PACA-CA 9 132408910 132408910 single base substitution C T upstream_gene_variant PAEN-AU 9 132401756 132401756 single base substitution G C missense_variant I109M 327C>G PAEN-AU 9 132401756 132401756 single base substitution G C missense_variant I30M 90C>G PBCA-DE 9 132405394 132405394 single base substitution T A upstream_gene_variant PBCA-DE 9 132409266 132409266 single base substitution C A upstream_gene_variant PRAD-UK 9 132397856 132397856 single base substitution T C downstream_gene_variant PRAD-US 9 132397600 132397600 single base substitution G T downstream_gene_variant PRAD-US 9 132400168 132400168 single base substitution C T 3_prime_UTR_variant PRAD-US 9 132400168 132400168 single base substitution C T synonymous_variant P310P 930G>A PRAD-US 9 132400168 132400168 single base substitution C T synonymous_variant P389P 1167G>A READ-US 9 132401544 132401544 single base substitution G A intron_variant READ-US 9 132401544 132401544 single base substitution G A missense_variant R150C 448C>T READ-US 9 132401544 132401544 single base substitution G A missense_variant R71C 211C>T RECA-EU 9 132399506 132399506 single base substitution C T 3_prime_UTR_variant RECA-EU 9 132399506 132399506 single base substitution C T downstream_gene_variant RECA-EU 9 132402953 132402953 single base substitution C A intron_variant RECA-EU 9 132402953 132402953 single base substitution C A missense_variant E54D 162G>T SKCA-BR 9 132396720 132396720 single base substitution A C downstream_gene_variant SKCA-BR 9 132404459 132404459 single base substitution C T upstream_gene_variant SKCA-BR 9 132404642 132404642 single base substitution C T upstream_gene_variant SKCA-BR 9 132406903 132406903 single base substitution C G upstream_gene_variant SKCA-BR 9 132406946 132406946 single base substitution A G upstream_gene_variant SKCM-US 9 132395060 132395060 single base substitution G A downstream_gene_variant SKCM-US 9 132396539 132396539 single base substitution C T downstream_gene_variant SKCM-US 9 132397675 132397675 single base substitution C T downstream_gene_variant SKCM-US 9 132401685 132401685 single base substitution T C missense_variant D133G 398A>G SKCM-US 9 132401685 132401685 single base substitution T C missense_variant D54G 161A>G SKCM-US 9 132402973 132402973 single base substitution G A intron_variant SKCM-US 9 132402973 132402973 single base substitution G A stop_gained R48* 142C>T STAD-US 9 132396542 132396542 single base substitution G A downstream_gene_variant STAD-US 9 132396585 132396585 single base substitution G T downstream_gene_variant STAD-US 9 132397491 132397491 single base substitution C G downstream_gene_variant STAD-US 9 132397660 132397660 single base substitution G A downstream_gene_variant STAD-US 9 132397705 132397705 single base substitution G A downstream_gene_variant STAD-US 9 132400101 132400101 single base substitution C T 3_prime_UTR_variant STAD-US 9 132400101 132400101 single base substitution C T missense_variant E333K 997G>A STAD-US 9 132400101 132400101 single base substitution C T missense_variant E412K 1234G>A STAD-US 9 132400113 132400113 single base substitution A G 3_prime_UTR_variant STAD-US 9 132400113 132400113 single base substitution A G missense_variant Y329H 985T>C STAD-US 9 132400113 132400113 single base substitution A G missense_variant Y408H 1222T>C STAD-US 9 132400192 132400193 deletion of <=200bp CA - 3_prime_UTR_variant STAD-US 9 132400192 132400193 deletion of <=200bp CA - frameshift_variant V302 STAD-US 9 132400192 132400193 deletion of <=200bp CA - frameshift_variant V381 STAD-US 9 132400635 132400635 single base substitution T C missense_variant M155V 463A>G STAD-US 9 132400635 132400635 single base substitution T C missense_variant M234V 700A>G STAD-US 9 132400635 132400635 single base substitution T C synonymous_variant R197R 591A>G STAD-US 9 132400887 132400887 single base substitution T C missense_variant H109R 326A>G STAD-US 9 132400887 132400887 single base substitution T C missense_variant H188R 563A>G STAD-US 9 132400887 132400887 single base substitution T C missense_variant T152A 454A>G STAD-US 9 132401727 132401727 single base substitution A G missense_variant V119A 356T>C STAD-US 9 132401727 132401727 single base substitution A G missense_variant V40A 119T>C THCA-SA 9 132395051 132395051 single base substitution C T downstream_gene_variant THCA-US 9 132397704 132397704 single base substitution C G downstream_gene_variant UCEC-US 9 132394988 132394988 single base substitution G A downstream_gene_variant UCEC-US 9 132395013 132395013 single base substitution C T downstream_gene_variant UCEC-US 9 132396444 132396444 single base substitution A G downstream_gene_variant UCEC-US 9 132397544 132397544 single base substitution G A downstream_gene_variant UCEC-US 9 132397561 132397561 single base substitution G A downstream_gene_variant UCEC-US 9 132397697 132397697 single base substitution A T downstream_gene_variant UCEC-US 9 132400170 132400170 single base substitution G A 3_prime_UTR_variant UCEC-US 9 132400170 132400170 single base substitution G A missense_variant P310S 928C>T UCEC-US 9 132400170 132400170 single base substitution G A missense_variant P389S 1165C>T UCEC-US 9 132400261 132400261 single base substitution G A 3_prime_UTR_variant UCEC-US 9 132400261 132400261 single base substitution G A synonymous_variant I279I 837C>T UCEC-US 9 132400261 132400261 single base substitution G A synonymous_variant I358I 1074C>T UCEC-US 9 132400297 132400297 single base substitution G A 3_prime_UTR_variant UCEC-US 9 132400297 132400297 single base substitution G A synonymous_variant F267F 801C>T UCEC-US 9 132400297 132400297 single base substitution G A synonymous_variant F346F 1038C>T UCEC-US 9 132400352 132400352 single base substitution G A 3_prime_UTR_variant UCEC-US 9 132400352 132400352 single base substitution G A missense_variant T249I 746C>T UCEC-US 9 132400352 132400352 single base substitution G A missense_variant T328I 983C>T UCEC-US 9 132400454 132400454 single base substitution G A 3_prime_UTR_variant UCEC-US 9 132400454 132400454 single base substitution G A missense_variant A215V 644C>T UCEC-US 9 132400454 132400454 single base substitution G A missense_variant A294V 881C>T UCEC-US 9 132400904 132400904 single base substitution G A missense_variant A146V 437C>T UCEC-US 9 132400904 132400904 single base substitution G A synonymous_variant S103S 309C>T UCEC-US 9 132400904 132400904 single base substitution G A synonymous_variant S182S 546C>T UCEC-US 9 132401493 132401493 single base substitution C T intron_variant UCEC-US 9 132401493 132401493 single base substitution C T missense_variant A167T 499G>A UCEC-US 9 132401493 132401493 single base substitution C T missense_variant A88T 262G>A UCEC-US 9 132401494 132401494 single base substitution G A intron_variant UCEC-US 9 132401494 132401494 single base substitution G A synonymous_variant A166A 498C>T UCEC-US 9 132401494 132401494 single base substitution G A synonymous_variant A87A 261C>T UCEC-US 9 132401691 132401691 single base substitution C T missense_variant R131Q 392G>A UCEC-US 9 132401691 132401691 single base substitution C T missense_variant R52Q 155G>A UCEC-US 9 132401756 132401756 single base substitution G A synonymous_variant I109I 327C>T UCEC-US 9 132401756 132401756 single base substitution G A synonymous_variant I30I 90C>T

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand NOKSI COSM3328452 c.580C>T p.R194C Substitution - Missense 9:129638591-129638591 - TCGA-BR-4191-01 COSM3904717 c.563A>G p.H188R Substitution - Missense 9:129638608-129638608 - TCGA-DD-A3A2-01 COSM4928903 c.1034A>C p.N345T Substitution - Missense 9:129638022-129638022 - J87_T COSM3952380 c.71C>G p.S24C Substitution - Missense 9:129641929-129641929 - DLD1 COSM4626355 c.730C>T p.R244W Substitution - Missense 9:129638326-129638326 - B81-2 COSM1755990 c.760A>G p.S254G Substitution - Missense 9:129638296-129638296 - VACO4S COSM4657308 c.550G>A p.G184R Substitution - Missense 9:129638621-129638621 - T2979 COSM1183743 c.971G>A p.R324H Substitution - Missense 9:129638085-129638085 - SNU-C4 COSM4654434 c.724G>A p.V242I Substitution - Missense 9:129638332-129638332 - ESO-1060 COSM1245540 c.1099C>T p.Q367* Substitution - Nonsense 9:129637957-129637957 - TCGA-B1-A656-01 COSM4413929 c.1189A>T p.K397* Substitution - Nonsense 9:129637867-129637867 - TCGA-HU-A4H4-01 COSM3904718 c.356T>C p.V119A Substitution - Missense 9:129639448-129639448 - C99 COSM4620540 c.931C>T p.P311S Substitution - Missense 9:129638125-129638125 - 587338 COSM1183744 c.833G>A p.R278H Substitution - Missense 9:129638223-129638223 - TCGA-D1-A17Q-01 COSM1105862 c.1074C>T p.I358I Substitution - coding silent 9:129637982-129637982 - TCGA-BR-6452-01 COSM3904715 c.1222T>C p.Y408H Substitution - Missense 9:129637834-129637834 - TCGA-CG-5728-01 COSM3904716 c.700A>G p.M234V Substitution - Missense 9:129638356-129638356 - PCSI_0111_Pa_P COSM216835 c.409G>A p.E137K Substitution - Missense 9:129639304-129639304 - Gp2D COSM4628834 c.1221G>A p.W407* Substitution - Nonsense 9:129637835-129637835 - TCGA-D1-A174-01 COSM1105863 c.983C>T p.T328I Substitution - Missense 9:129638073-129638073 - Pat_26_B COSM5875661 c.1105G>A p.E369K Substitution - Missense 9:129637951-129637951 - 66 COSM1105866 c.499G>A p.A167T Substitution - Missense 9:129639214-129639214 - TCGA-EJ-5525-01 COSM1132573 c.1167G>A p.P389P Substitution - coding silent 9:129637889-129637889 - TCGA-G4-6586-01 COSM1460416 c.1150C>A p.R384R Substitution - coding silent 9:129637906-129637906 - OSCC-GB_00440111 COSM3716138 c.321G>T p.L107F Substitution - Missense 9:129639483-129639483 - 587224 COSM1183743 c.971G>A p.R324H Substitution - Missense 9:129638085-129638085 - TCGA-D1-A177-01 COSM1105868 c.392G>A p.R131Q Substitution - Missense 9:129639412-129639412 - TCGA-BH-A18P-01 COSM455459 c.292G>A p.E98K Substitution - Missense 9:129640544-129640544 - C10 COSM1105865 c.546C>T p.S182S Substitution - coding silent 9:129638625-129638625 - B86-Tumor COSM1755991 c.667G>A p.E223K Substitution - Missense 9:129638389-129638389 - TCGA-EE-A29L-06 COSM3654826 c.142C>T p.R48* Substitution - Nonsense 9:129640694-129640694 - C0014T COSM4138855 c.162G>T p.E54D Substitution - Missense 9:129640674-129640674 - TCGA-AP-A0LT-01 COSM1105861 c.1165C>T p.P389S Substitution - Missense 9:129637891-129637891 - TCGA-BS-A0UF-01 COSM1105866 c.499G>A p.A167T Substitution - Missense 9:129639214-129639214 - I2L-P8-Tumor-Biopsy COSM1105865 c.546C>T p.S182S Substitution - coding silent 9:129638625-129638625 - sysucc-968T COSM1105864 c.881C>T p.A294V Substitution - Missense 9:129638175-129638175 - TCGA-B5-A11E-01 COSM1105865 c.546C>T p.S182S Substitution - coding silent 9:129638625-129638625 - TCGA-61-1722-01 COSM1330698 c.1166C>T p.P389L Substitution - Missense 9:129637890-129637890 - TCGA-AX-A0J0-01 COSM1105864 c.881C>T p.A294V Substitution - Missense 9:129638175-129638175 - TCGA-EI-6917-01 COSM3432908 c.448C>T p.R150C Substitution - Missense 9:129639265-129639265 - B109 COSM1755992 c.591G>A p.L197L Substitution - coding silent 9:129638580-129638580 - 587246 COSM1183745 c.804G>T p.K268N Substitution - Missense 9:129638252-129638252 - QC2-42-T2 COSM5656230 c.763G>A p.E255K Substitution - Missense 9:129638293-129638293 - TCGA-66-2742-01 COSM752577 c.762C>G p.S254R Substitution - Missense 9:129638294-129638294 - TCGA-DD-A113-01 COSM4925164 c.980A>G p.E327G Substitution - Missense 9:129638076-129638076 - sysucc-1370T COSM5472674 c.245C>T p.T82M Substitution - Missense 9:129640591-129640591 - PCSI_0111_Pa_P_526 COSM216835 c.409G>A p.E137K Substitution - Missense 9:129639304-129639304 - WT041 COSM5352071 c.855C>T p.A285A Substitution - coding silent 9:129638201-129638201 - TCGA-AP-A056-01 COSM237012 c.1038C>T p.F346F Substitution - coding silent 9:129638018-129638018 - YUPAT COSM1701816 c.178G>A p.A60T Substitution - Missense 9:129640658-129640658 - PD24214a COSM1132573 c.1167G>A p.P389P Substitution - coding silent 9:129637889-129637889 - OSCC-GB_00770111 COSM4883941 c.115C>A p.P39T Substitution - Missense 9:129640721-129640721 - WA16 COSM237012 c.1038C>T p.F346F Substitution - coding silent 9:129638018-129638018 - TCGA-AG-A002-01 COSM237012 c.1038C>T p.F346F Substitution - coding silent 9:129638018-129638018 - I2L-P8-Tumor-Organoid COSM1105865 c.546C>T p.S182S Substitution - coding silent 9:129638625-129638625 - HCT15 COSM3328448 c.829C>T p.L277L Substitution - coding silent 9:129638227-129638227 - sysucc-311T COSM237012 c.1038C>T p.F346F Substitution - coding silent 9:129638018-129638018 - B86-Tumor COSM4007070 c.981G>C p.E327D Substitution - Missense 9:129638075-129638075 - OSCC-GB_01060111 COSM4882924 c.765G>T p.E255D Substitution - Missense 9:129638291-129638291 - pfg043T COSM4761476 c.1217A>C p.K406T Substitution - Missense 9:129637839-129637839 - TCGA-BG-A0MI-01 COSM1105867 c.498C>T p.A166A Substitution - coding silent 9:129639215-129639215 - XHDG38 COSM4769807 c.972C>A p.R324R Substitution - coding silent 9:129638084-129638084 - TCGA-EE-A3AB-06 COSM3926280 c.398A>G p.D133G Substitution - Missense 9:129639406-129639406 - B81-2-Tumor COSM1755990 c.760A>G p.S254G Substitution - Missense 9:129638296-129638296 - T3610 COSM4663656 c.507G>A p.K169K Substitution - coding silent 9:129639206-129639206 - 44T COSM3716138 c.321G>T p.L107F Substitution - Missense 9:129639483-129639483 - 8049945 COSM4407435 c.327C>G p.I109M Substitution - Missense 9:129639477-129639477 - TCGA-HU-A4GT-01 COSM3904714 c.1234G>A p.E412K Substitution - Missense 9:129637822-129637822 - B86 COSM1755991 c.667G>A p.E223K Substitution - Missense 9:129638389-129638389 - B109-Tumor COSM1755992 c.591G>A p.L197L Substitution - coding silent 9:129638580-129638580 - 587238 COSM1183742 c.959C>A p.A320E Substitution - Missense 9:129638097-129638097 - TCGA-D1-A17Q-01 COSM1105869 c.327C>T p.I109I Substitution - coding silent 9:129639477-129639477 - TCGA-D5-6540-01 COSM1460417 c.882G>A p.A294A Substitution - coding silent 9:129638174-129638174 - B86-Tumor COSM4007069 c.1265G>C p.*422S Nonstop extension 9:129637791-129637791 - TCGA-B0-5095-01 COSM487115 c.470T>C p.L157P Substitution - Missense 9:129639243-129639243 - Pat_26_A COSM5875661 c.1105G>A p.E369K Substitution - Missense 9:129637951-129637951 - TCGA-AO-A0J2-01 COSM455460 c.75G>T p.L25L Substitution - coding silent 9:129641925-129641925 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.125037 2409899|CGAP|BC065913|A/G|non-coding||2207|Validated; 1533151|dbSNP|BC065913|G/T|coding|Ala106Ser|388|Candidate

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A G Missense p.L157P c.470T>C 9 132401522 RCCC A G Missense p.V129A c.386T>C 9 132401697 CM C A Synonymous p.L25L c.75G>T 9 132404204 BRCA C T 3-UTRSNV . c.1263+36G>A 9 132400036 CM CT - Frameshift p.S138*fs*1 c.412_413delAG 9 132401579 LGG C T Missense p.D128N c.382G>A 9 132401701 BRCA C T Missense p.E137K c.409G>A 9 132401583 HNSC C T Missense p.E137K c.409G>A 9 132401583 PAAD C T Missense p.R131Q c.392G>A 9 132401691 UCEC C T Synonymous p.P389P c.1167G>A 9 132400168 PRAD G A Missense p.P389S c.1165C>T 9 132400170 UCEC G A Missense p.T328I c.983C>T 9 132400352 UCEC G A Nonsense p.Q367* c.1099C>T 9 132400236 ESCA G A Nonsense p.R48* c.142C>T 9 132402973 CM G A Synonymous p.A166A c.498C>T 9 132401494 UCEC G A Synonymous p.L95L c.285C>T 9 132402830 LUAD G C Missense p.S254R c.762C>G 9 132400573 LUSC G C Synonymous p.V396V c.1188C>G 9 132400147 LUAD G T Missense p.Q15K c.43C>A 9 132404236 LUAD T C Missense p.D133G c.398A>G 9 132401685 CM T C Missense p.H188R c.563A>G 9 132400887 STAD T C Missense p.M234V c.700A>G 9 132400635 STAD