PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus FKBP5 KLHL1 25036637 intact exp P G P G P P G P P P P P CACYBP KLHL1 25036637 intact exp P G G P P G P P P P BMPR1B KLHL1 15761153 hprd,i2d exp P G P G P P G P P P P P HSPA8 KLHL1 25036637 intact exp P P P P P P CACNA1A KLHL1 17289272 biogrid exp G G P G NUDCD3 KLHL1 25036637 intact exp P G P G P P G P P P P P HSP90AA1 KLHL1 25036637,22939624 biogrid,intact exp P G G G P TGFBR1 KLHL1 15761153 hprd,i2d exp G P G P P G P NUDCD2 KLHL1 25036637 intact exp P G P G P P G P P P P P KLHL1 SUGT1 25036637 intact exp G P G P G P P P P HSP90AB1 KLHL1 25036637,22939624 intact exp P G P G P P G P P P P P CACNA1H KLHL1 20147652 biogrid exp, ortho P P P P P P P P P CHRNB2 KLHL1 23023127 pred G P G G P P PAFAH1B1 KLHL1 23023127 pred P G P G P P G P P P P P KLHL26 KLHL1 23023127 pred P G P G P P G P P P P P PRKCI KLHL1 23023127 pred P G G P G P P P STRN KLHL1 23023127 pred P G P G P P G P P P P P ZBTB16 KLHL1 23023127 pred P G G G P P P KLHL1 KLHL3 23023127 pred P G P G P P G P P P P P MTA2 KLHL1 16082366 pred P P P P P P P P P SPTBN2 KLHL1 23023127 pred P G G P P G P P P P HOXB1 KLHL1 23023127 pred G P G P G P P P SH3GL2 KLHL1 23023127 pred G G G P SOCS3 KLHL1 23023127 pred P G P G P P G P P P P P WNT7A KLHL1 23023127 pred P P P P P P P GRIN3A KLHL1 23023127 pred G G G KLHL18 KLHL1 23023127 pred P G P G P P G P P P P P KLHL1 UBQLN2 23023127 pred P G P G P P G P P P P P CELSR2 KLHL1 23023127 pred P G P G P P G P P P P P KBTBD11 KLHL1 23023127 pred P G P G P P G P P P P P MT-ND4 KLHL1 23023127 pred P P P P P P P P CACNB4 KLHL1 23023127 pred P G P G P P G P P P P P KLHL1 KLHL11 23023127 pred P P P P P P P P P KLHL4 KLHL1 16082366 pred P G G P P G P P P FEZF2 KLHL1 23023127 pred G G ACVR1B KLHL1 23023127 pred G G P P G P P P CTNNA2 KLHL1 23023127 pred P G P G P P G P P FBXO45 KLHL1 23023127 pred P G G P G P P P P APBB1 KLHL1 23023127 pred P G P G P P G P P P P P DVL1 KLHL1 23023127 pred P G P G P P G P P P P P AKAP5 KLHL1 23023127 pred G G SCN1A KLHL1 23023127 pred P G P G P P G P P P P P BTBD10 KLHL1 23023127 pred P G P G P G P P P SPTB KLHL1 23023127 pred G P G P G P P FBXW7 KLHL1 23023127 pred P G P G P P G P P P P P BTBD6 KLHL1 23023127 pred G G G P GLRA1 KLHL1 23023127 pred P P P P P P P P ZBTB7A KLHL1 23023127 pred P G P G P P G P P P P P LHX5 KLHL1 23023127 pred P P P P P P P P P ADRA1B KLHL1 23023127 pred GRM2 KLHL1 23023127 pred G KCNMA1 KLHL1 23023127 pred P G G P P G P P BCL6 KLHL1 23023127 pred G G G PARK2 KLHL1 23023127 pred P G P G P P G P P P P P APP KLHL1 23023127 pred P G G G P P KLHL1 ABI2 23023127 pred G G G APBA1 KLHL1 23023127 pred P G P G P P G P P P P P KLHL1 EPB41L3 23023127 pred P G G P G P P KLHL1 BTBD3 23023127 pred P G P G P P G P P P P STMN2 KLHL1 23023127 pred G G G BTBD2 KLHL1 23023127 pred G G G DAB1 KLHL1 23023127 pred G P G G P KLHL1 STMN3 23023127 pred G G P G P P TNFAIP1 KLHL1 23023127 pred G G P G P P P GLRB KLHL1 23023127 pred P G P G P P G P P P P P RASA1 KLHL1 23023127 pred G G G P BTBD9 KLHL1 23023127 pred G G G P P P P SPTBN4 KLHL1 23023127 pred P G P G P P G P P P DRD1 KLHL1 23023127 pred P P P P P P P P DCLK1 KLHL1 23023127 pred G G G P P P EGF KLHL1 23023127 pred P P P P P P P P P KLHL12 KLHL1 23023127 pred G G G LGI4 KLHL1 23023127 pred P G P G P P G P P P P TBR1 KLHL1 23023127 pred P G P G P P G P P P P P KLHL2 KLHL1 23023127 pred G G P P G P BDNF KLHL1 23023127 pred P G P G P P G P P P P P ENC1 KLHL1 23023127 pred P G P G P G P P P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9NR64 P62738 affinity chromatography technology 16982692 physical association X 2 Q9NR64 P07900-2 affinity chromatography technology 22939624 physical association X 2 Q9NR64 affinity chromatography technology 17289272 physical association X 2 Q9NR64 affinity chromatography technology 17289272 physical association X 2 Q9NR64 O95180 affinity chromatography technology 20147652 physical association X 2 Q9NR64 P32577 affinity chromatography technology 16982692 physical association X 2 P0CG48 Q9NR64 affinity chromatography technology 21963094 physical association X 2 Q9NR64 affinity chromatography technology 16982692 physical association X 2 Q9NR64 affinity chromatography technology 16982692 physical association X 2 Q9NR64 P36897-3 in vivo 15761153 - X 2 Q9NR64 P36897-3 in vivo 15761153 - X 2 O00238 Q9NR64 in vivo 15761153 - X 2 O00238 Q9NR64 in vivo 15761153 - X 2 Q9NR64 Q8IVD9 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q9NR64 A0A024R904 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q8WVJ2 Q9NR64 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q9NR64 A0A024RD80 luminescence based mammalian interactome mapping 22939624 physical association X 2 Q9NR64 Q13451 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q9NR64 Q6PK50 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q9NR64 Q96BE0 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q9NR64 K9JA46 luminescence based mammalian interactome mapping 25036637 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9NR64 B4DYC6 KLHL1 B4DYC6 0.126 25036637 Q9NR64 P07900 KLHL1 HSP90AA1 0.236 22939624,25036637 Q9NR64 P08238 KLHL1 HSP90AB1 0.126 22939624 Q9NR64 P32577 KLHL1 CSK 0.21 16982692 Q9NR64 Q13451 KLHL1 FKBP5 0.126 25036637 Q9NR64 Q6PK50 KLHL1 HSP90AB1 0.126 25036637 Q9NR64 Q8IVD9 KLHL1 NUDCD3 0.126 25036637 Q9NR64 Q8WVJ2 KLHL1 NUDCD2 0.126 25036637 Q9NR64 Q96BE0 KLHL1 Q96BE0 0.126 25036637 Q9NR64 Q9HB71 KLHL1 CACYBP 0.126 25036637 Q9NR64 O95180 KLHL1 CACNA1H 0.21 20147652 Q9NR64 P62738 KLHL1 ACTA2 0.21 16982692 Q9NR64 P18266 KLHL1 GSK3B 0.376 16982692 Q9NR64 O00555 KLHL1 CACNA1A 0.376 17289272