PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TRIM36 TRIM36 25416956 biogrid,intact exp G GP G P GP G P P GP GP P G GP P GP LCA5 TRIM36 26638075 biogrid,intact exp G GP G P GP G P GP GP G G P G ZNF587 TRIM36 25416956 biogrid,intact exp G GP G P GP G P P GP GP G GP P GP ZNF417 TRIM36 25416956 biogrid,intact exp P P P P P P P P P P CENPH TRIM36 19232519 biogrid exp P P P P P GP P P GP DCTN1 TRIM36 26638075 biogrid,intact exp G GP G P GP G P P GP GP P G GP P GP UBC TRIM36 19232519 biogrid exp G GP G P GP G P P GP GP P G GP P GP TRIM36 TRAF3IP3 25416956 biogrid,intact exp P GP P P GP P P P P P GLRX3 TRIM36 25416956 biogrid,intact exp G GP G GP G P GP GP G GP P GP SPICE1 TRIM36 26638075 biogrid,intact exp P P GP P P GP P P G GP P GP KIAA0753 TRIM36 26638075 biogrid,intact exp G GP G P GP G P P GP GP P G GP P GP UBE2H TRIM36 19549727 biogrid,intact exp G GP G P G G P P GP GP P G GP P GP HSP90AB1 TRIM36 22939624 intact exp G GP G P GP G P P GP GP P G GP P GP ZMAT2 TRIM36 25416956 biogrid,intact exp G GP G P GP G P P GP GP P G GP P GP HSP90AA1 TRIM36 22939624 biogrid exp G GP G GP G G GP G G GP GRB7 TRIM36 25416956 biogrid,intact exp G GP P GP G P P GP GP P G GP P GP UBE2D2 TRIM36 19232519 biogrid exp G GP G GP G P P G GP P G GP GP EIF4A2 TRIM36 25416956 biogrid,intact exp P P P P P P P P P P GP UBXN8 TRIM36 23023127 pred G G G G G G G G G G IGSF22 TRIM36 23023127 pred G GP P P G P P GP GP G P P GP TRIM36 ZAN 23023127 pred G G G G TNC TRIM36 23023127 pred G GP G GP G P GP GP G GP P GP FSD2 TRIM36 23023127 pred P P P P P P P P P P P TRIM36 FNDC3A 23023127 pred G GP G P GP G P P GP GP P G GP P GP TRIM36 ROBO1 23023127 pred G GP G P GP G P P GP GP P G GP P GP CRLF3 TRIM36 23023127 pred G GP G GP G P GP GP P G G P GP DCC TRIM36 23023127 pred GP P P G P P P GP P P P P TRIM50 TRIM36 23023127 pred P P P P P P P P GP TRIM63 TRIM36 23023127 pred IL11RA TRIM36 23023127 pred G GP G P GP G P P GP GP P G GP P GP TRIM36 PVRL3 23023127 pred G GP G P GP G P P GP GP P G GP P GP SYT1 TRIM36 23023127 pred G GP G G G G GP G G G TRIM74 TRIM36 23023127 pred FNDC1 TRIM36 23023127 pred P G P GP P GP P P P P TRIM36 TRAF6 23023127 pred G G G P GP G P P GP G P G GP P GP MYBPC3 TRIM36 23023127 pred G G P G G G G G G CDON TRIM36 23023127 pred G GP G P GP G P GP GP G GP P GP IL13 TRIM36 23023127 pred P P P P P P P P P GP TRIM75P TRIM36 23023127 pred TRIM31 TRIM36 23023127 pred P P P P P P P P P P P TRIM31 TRIM36 23023127 pred P P P P P P P P P P P ROBO2 TRIM36 23023127 pred G GP G P P G P P P GP P G P P P ILDR2 TRIM36 23023127 pred G GP G GP G P P GP G GP P GP SYT7 TRIM36 23023127 pred G GP G G P GP P G GP P SORL1 TRIM36 23023127 pred G GP G P GP G P P GP GP P G GP P GP DOC2A TRIM36 23023127 pred G G G G G G G CADM1 TRIM36 23023127 pred G GP G GP G P P GP GP G GP P GP PRLR TRIM36 23023127 pred G G G G IHH TRIM36 23023127 pred P P GP P P GP P P GP P P MPG TRIM36 21836163 pred G GP G P GP G P G GP P G GP GP TRIM37 TRIM36 23023127 pred G GP G GP G P GP GP G GP P GP TRIM36 TNN 23023127 pred G GP G GP G P P GP GP P G P P P DAZ2 TRIM36 23023127 pred P P P P P MST1R TRIM36 23023127 pred G GP G P GP G P P GP GP P G GP P GP SHH TRIM36 23023127 pred G GP G P GP G P GP GP P G GP P GP TRIM73 TRIM36 23023127 pred G GP G P GP G P P GP GP G GP P G TRIM36 PKDREJ 23023127 pred P P GP TNP2 TRIM36 23023127 pred G TRIM36 RIMS3 23023127 pred G G G G G G G G G G TRIM28 TRIM36 23023127 pred G GP G P GP G P P GP GP P G GP P GP TRPV6 TRIM36 23023127 pred P GP P G P P G P TRIM52 TRIM36 23023127 pred G GP G P GP G P GP GP P G GP P GP NOTCH1 TRIM36 23023127 pred G GP G P GP G P P GP GP P G GP P GP FGF2 TRIM36 23023127 pred G GP G GP G P P G GP P G G PVRL2 TRIM36 23023127 pred G G G P GP G P P GP G P G GP P GP TRIM36 PCLO 23023127 pred G GP G P GP G P P GP GP P G GP P GP CMYA5 TRIM36 23023127 pred G GP G P GP G P P GP GP P G GP P GP SDF4 TRIM36 23023127 pred G GP G GP G P P GP GP G GP P GP TRIM16 TRIM36 23023127 pred G GP G P GP G P P GP GP P G GP P GP ACR TRIM36 23023127 pred G G P P G G GP SYT9 TRIM36 23023127 pred G G P G P P P G P P SYT6 TRIM36 23023127 pred G GP G P GP G P P GP GP P G GP P GP GLRB TRIM36 23023127 pred G GP G P P G P P P GP G GP P P FSHB TRIM36 23023127 pred G G DOC2B TRIM36 23023127 pred P P P P P P P P P RIMS1 TRIM36 23023127 pred G GP G GP G P P GP P G GP P GP AXIN1 TRIM36 23023127 pred GP G P GP G P P GP GP P G GP P GP FNDC8 TRIM36 23023127 pred P P P P P GP BSG TRIM36 23023127 pred G GP G P GP G P GP GP G GP P GP TRIM36 ASF1B 23023127 pred G G G G G G G G G G LRRN4CL TRIM36 23023127 pred G GP G GP G P P GP GP P G GP P GP GLRA1 TRIM36 23023127 pred P P P P P P P G P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9NQ86 A4D1L5 two hybrid array 19549727 physical association X 2 Q9NQ86 Q14240-2 two hybrid prey pooling approach 25416956 physical association X 2 Q9NQ86 Q14240 two hybrid prey pooling approach 25416956 physical association X 2 Q9NQ86 Q14451 two hybrid prey pooling approach 25416956 physical association X 2 Q9NQ86 Q8TAU3 two hybrid prey pooling approach 25416956 physical association X 2 Q9NQ86 Q96SQ5 two hybrid prey pooling approach 25416956 physical association X 2 Q9NQ86 Q14240-2 two hybrid array 25416956 physical association X 2 Q9NQ86 Q14240 two hybrid array 25416956 physical association X 2 Q9NQ86 Q14451 two hybrid array 25416956 physical association X 2 Q9NQ86 Q8TAU3 two hybrid array 25416956 physical association X 2 Q9NQ86 Q96SQ5 two hybrid array 25416956 physical association X 2 Q9NQ86 Q14240-2 validated two hybrid 25416956 physical association X 2 Q9NQ86 Q14240 validated two hybrid 25416956 physical association X 2 Q9NQ86 Q14451 validated two hybrid 25416956 physical association X 2 Q9NQ86 Q8TAU3 validated two hybrid 25416956 physical association X 2 Q9NQ86 Q96SQ5 validated two hybrid 25416956 physical association X 2 Q9NQ86 A0A024RD80 luminescence based mammalian interactome mapping 22939624 physical association X 2 Q9NQ86 Q9NQ86 two hybrid array 25416956 physical association X 2 Q9NQ86 Q96NC0 two hybrid prey pooling approach 25416956 physical association X 2 Q9NQ86 O76003 two hybrid prey pooling approach 25416956 physical association X 2 Q9NQ86 Q9Y228 two hybrid prey pooling approach 25416956 physical association X 2 Q9NQ86 Q96NC0 two hybrid array 25416956 physical association X 2 Q9NQ86 O76003 two hybrid array 25416956 physical association X 2 Q9NQ86 Q9Y228 two hybrid array 25416956 physical association X 2 Q9NQ86 O76003 validated two hybrid 25416956 physical association X 2 Q9NQ86 Q96NC0 validated two hybrid 25416956 physical association X 2 Q9NQ86 Q9Y228 validated two hybrid 25416956 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality DCTN1 TRIM36 26638075 1314 HT KIAA0753 TRIM36 26638075,26638075 1314,1313 HT DKFZP686I0746 TRIM36 26638075 1313 HT LCA5 TRIM36 26638075,26638075 1314,1313 HT SPICE1 TRIM36 26638075,26638075 1314,1313 HT DCTN1 TRIM36 26638075 1314 HT KIAA0753 TRIM36 26638075,26638075 1314,1313 HT DKFZP686I0746 TRIM36 26638075 1313 HT LCA5 TRIM36 26638075,26638075 1314,1313 HT SPICE1 TRIM36 26638075,26638075 1314,1313 HT GLRX3 TRIM36 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT HSP90AB1 TRIM36 22939624 0729 HT UBC TRIM36 19232519 0415 LC UBE2H TRIM36 19549727,19549727 0397,0018 HT EIF4A2 TRIM36 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT GRB7 TRIM36 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT ZNF417 TRIM36 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT ZMAT2 TRIM36 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT ZNF587 TRIM36 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT CENPH TRIM36 19232519,19232519 0004,0018 LC TRIM36 TRIM36 25416956,25416956 0397,0018 HT TRIM36 TRAF3IP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9NQ86 P0CG48 TRIM36 UBC 0.309 19232519 Q9NQ86 P62256 TRIM36 UBE2H 0.376 19549727 Q9NQ86 Q14451 TRIM36 GRB7 0.454 25416956 Q9NQ86 Q96SQ5 TRIM36 ZNF587 0.454 25416956 Q9NQ86 Q9H3R5 TRIM36 CENPH 0.454 19232519 Q9Y228 Q9NQ86 TRAF3IP3 TRIM36 0.454 25416956 Q9NQ86 Q8TAU3 TRIM36 ZNF417 0.454 25416956 Q9NQ86 P07900 TRIM36 HSP90AA1 0.126 22939624 Q9NQ86 P08238 TRIM36 HSP90AB1 0.126 22939624 Q9NQ86 O76003 TRIM36 GLRX3 0.583 25416956,unassigned1304 Q9NQ86 Q9NQ86 TRIM36 TRIM36 0.332 25416956 Q9NQ86 Q96NC0 TRIM36 ZMAT2 0.454 25416956 Q9NQ86 Q8N0Z3 TRIM36 SPICE1 0.236 26638075 Q9Y297 Q9NQ86 BTRC TRIM36 0.236 unassigned1304 Q9NQ86 Q86VQ0 TRIM36 LCA5 0.236 26638075 Q9NQ86 Q14240 TRIM36 EIF4A2 0.636 25416956 Q9NQ86 Q14203 TRIM36 DCTN1 0.126 26638075 Q9NQ86 Q2KHM9 TRIM36 KIAA0753 0.126 26638075

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SIAH2 TRIM36 MI:0362 inference MI:1106 pathways database GLRX3 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database FBXO21 TRIM36 MI:0362 inference MI:1106 pathways database HSP90AA1 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AB1 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database UBB TRIM36 MI:0362 inference MI:1106 pathways database UBC TRIM36 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TRIM21 TRIM36 MI:0362 inference MI:1106 pathways database CCNF TRIM36 MI:0362 inference MI:1106 pathways database UBE2A TRIM36 MI:0362 inference MI:1106 pathways database RAB38 TRIM36 MI:0362 inference MI:0461 interaction database FBXW4 TRIM36 MI:0362 inference MI:1106 pathways database UBE2H TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database RBX1 TRIM36 MI:0362 inference MI:1106 pathways database RPS27A TRIM36 MI:0362 inference MI:1106 pathways database UBA52 TRIM36 MI:0362 inference MI:1106 pathways database SKP1 TRIM36 MI:0362 inference MI:1106 pathways database SKP2 TRIM36 MI:0362 inference MI:1106 pathways database CUL1 TRIM36 MI:0362 inference MI:1106 pathways database DCTN1 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database EIF4A2 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database GRB7 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database TRIP12 TRIM36 MI:0362 inference MI:1106 pathways database LONRF1 TRIM36 MI:0362 inference MI:1106 pathways database KIAA0753 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database HECTD2 TRIM36 MI:0362 inference MI:1106 pathways database FBXO31 TRIM36 MI:0362 inference MI:1106 pathways database FBXW9 TRIM36 MI:0362 inference MI:1106 pathways database FBXW10 TRIM36 MI:0362 inference MI:1106 pathways database RNF213 TRIM36 MI:0362 inference MI:1106 pathways database FBXL22 TRIM36 MI:0362 inference MI:1106 pathways database FBXL19 TRIM36 MI:0362 inference MI:1106 pathways database FBXW12 TRIM36 MI:0362 inference MI:1106 pathways database RNF19B TRIM36 MI:0362 inference MI:1106 pathways database RNF144B TRIM36 MI:0362 inference MI:1106 pathways database RBBP6 TRIM36 MI:0362 inference MI:1106 pathways database HUWE1 TRIM36 MI:0362 inference MI:1106 pathways database LCA5 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database TRIM69 TRIM36 MI:0362 inference MI:1106 pathways database SIAH1 TRIM36 MI:0362 inference MI:1106 pathways database HERC6 TRIM36 MI:0362 inference MI:1106 pathways database UBR2 TRIM36 MI:0362 inference MI:1106 pathways database SPICE1 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database FBXL14 TRIM36 MI:0362 inference MI:1106 pathways database FBXW8 TRIM36 MI:0362 inference MI:1106 pathways database FBXL16 TRIM36 MI:0362 inference MI:1106 pathways database FBXO15 TRIM36 MI:0362 inference MI:1106 pathways database ZNRF1 TRIM36 MI:0362 inference MI:1106 pathways database FBXL13 TRIM36 MI:0362 inference MI:1106 pathways database FBXO22 TRIM36 MI:0362 inference MI:1106 pathways database ZNRF2 TRIM36 MI:0362 inference MI:1106 pathways database FBXO27 TRIM36 MI:0362 inference MI:1106 pathways database ZNF417 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database FBXO30 TRIM36 MI:0362 inference MI:1106 pathways database RNF217 TRIM36 MI:0362 inference MI:1106 pathways database DTX3L TRIM36 MI:0362 inference MI:1106 pathways database FBXO41 TRIM36 MI:0362 inference MI:1106 pathways database LMO7 TRIM36 MI:0362 inference MI:1106 pathways database MYLIP TRIM36 MI:0362 inference MI:1106 pathways database FBXW7 TRIM36 MI:0362 inference MI:1106 pathways database FBXO32 TRIM36 MI:0362 inference MI:1106 pathways database FBXW5 TRIM36 MI:0362 inference MI:1106 pathways database MIB2 TRIM36 MI:0362 inference MI:1106 pathways database SPSB1 TRIM36 MI:0362 inference MI:1106 pathways database FBXL8 TRIM36 MI:0362 inference MI:1106 pathways database FBXO17 TRIM36 MI:0362 inference MI:1106 pathways database FBXL20 TRIM36 MI:0362 inference MI:1106 pathways database FBXL18 TRIM36 MI:0362 inference MI:1106 pathways database ZMAT2 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database NEDD4L TRIM36 MI:0362 inference MI:1106 pathways database ZNF587 TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 TRIM36 MI:0362 inference MI:1106 pathways database CENPH TRIM36 MI:0045 experimental interaction detection MI:0461 interaction database FBXL15 TRIM36 MI:0362 inference MI:1106 pathways database FBXO44 TRIM36 MI:0362 inference MI:1106 pathways database UNKL TRIM36 MI:0362 inference MI:1106 pathways database SMURF2 TRIM36 MI:0362 inference MI:1106 pathways database TRIM36 FBXO6 MI:0362 inference MI:1106 pathways database TRIM36 RNF19A MI:0362 inference MI:1106 pathways database TRIM36 RLIM MI:0362 inference MI:1106 pathways database TRIM36 FBXL12 MI:0362 inference MI:1106 pathways database TRIM36 FBXO40 MI:0362 inference MI:1106 pathways database TRIM36 HERC5 MI:0362 inference MI:1106 pathways database TRIM36 FBXL7 MI:0362 inference MI:1106 pathways database TRIM36 FBXO2 MI:0362 inference MI:1106 pathways database TRIM36 FBXO10 MI:0362 inference MI:1106 pathways database TRIM36 FBXO9 MI:0362 inference MI:1106 pathways database TRIM36 FBXL5 MI:0362 inference MI:1106 pathways database TRIM36 FBXL4 MI:0362 inference MI:1106 pathways database TRIM36 FBXW11 MI:0362 inference MI:1106 pathways database TRIM36 FBXO4 MI:0362 inference MI:1106 pathways database TRIM36 FBXL21 MI:0362 inference MI:1106 pathways database TRIM36 FBXL3 MI:0362 inference MI:1106 pathways database TRIM36 FBXW2 MI:0362 inference MI:1106 pathways database TRIM36 TRAF3IP3 MI:0045 experimental interaction detection MI:0461 interaction database TRIM36 BTRC MI:0362 inference MI:1106 pathways database TRIM36 FBXO7 MI:0362 inference MI:1106 pathways database TRIM36 RNF115 MI:0362 inference MI:1106 pathways database TRIM36 RNF114 MI:0362 inference MI:1106 pathways database TRIM36 WSB1 MI:0362 inference MI:1106 pathways database