PTM - CPLM Gene Name UniProt ID Type Position Code USP16; MSTP039 Q9Y5T5 Ubiquitination 293 K USP16; MSTP039 Q9Y5T5 Ubiquitination 764 K USP16; MSTP039 Q9Y5T5 Ubiquitination 37 K USP16; MSTP039 Q9Y5T5 Ubiquitination 426 K

PTM - dbPAF Gene Name UniProt ID Position Type Species USP16; MSTP039 Q9Y5T5 10 T Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 145 T Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 146 T Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 16 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 17 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 189 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 199 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 204 T Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 215 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 217 T Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 230 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 330 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 353 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 415 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 423 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 424 Y Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 524 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 531 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 550 T Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 551 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 552 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 554 T Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 598 S Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 600 T Homo sapiens(Human) USP16; MSTP039 Q9Y5T5 606 Y Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9Y5T5 K29-ac Acetylation PVCRHIRkGLEQGNL Q9Y5T5 K37-ac Acetylation GLEQGNLkKALVNVE Q9Y5T5 T10-p Phosphorylation KKRTKGktVPIDDSS Q9Y5T5 S189-p Phosphorylation KENPPMNsPCQITVK Q9Y5T5 S199-p Phosphorylation QITVKGLsNLGNTCF Q9Y5T5 S230-p Phosphorylation LLKEVKMsGTIVKIE Q9Y5T5 S330-p Phosphorylation ILKAFGNsTEKLDEE Q9Y5T5 S353-p Phosphorylation EKKKSMPsFVDRIFG Q9Y5T5 S386-p Phosphorylation HESFLDLsLPVLDDQ Q9Y5T5 S415-p Phosphorylation VEDEDQDsEEEKDND Q9Y5T5 S423-p Phosphorylation EEEKDNDsYIkERSD Q9Y5T5 S486-p Phosphorylation SEYEAEMsLQGEVNI Q9Y5T5 S524-p Phosphorylation GQAKMIEsVTDNQKs Q9Y5T5 S531-p Phosphorylation sVTDNQKsTEEVDMK Q9Y5T5 T550-p Phosphorylation DNDLEVLtssPtRNL Q9Y5T5 S551-p Phosphorylation NDLEVLtssPtRNLN Q9Y5T5 S552-p Phosphorylation DLEVLtssPtRNLNG Q9Y5T5 T554-p Phosphorylation EVLtssPtRNLNGAY Q9Y5T5 S598-p Phosphorylation NIEILNDsHtPGTKV Q9Y5T5 T600-p Phosphorylation EILNDsHtPGTKVyE Q9Y5T5 Y606-p Phosphorylation HtPGTKVyEVVNEDP Q9Y5T5 Y742-p Phosphorylation EENTRVLysLYGVVE Q9Y5T5 S743-p Phosphorylation ENTRVLysLYGVVEH Q9Y5T5 K9-ub Ubiquitination GKKRTKGktVPIDDS Q9Y5T5 K37-ub Ubiquitination GLEQGNLkKALVNVE Q9Y5T5 K293-ub Ubiquitination CKKAVRFkGYQQQDS Q9Y5T5 K426-ub Ubiquitination KDNDsYIkERSDIPS Q9Y5T5 K437-ub Ubiquitination DIPSGTSkHLQKKAK Q9Y5T5 K506-ub Ubiquitination SQEGVMHkEYCVNQK

PTM - dbPTM UniProt ID Position Code Type Resources References Q9Y5T5 415 S Phosphorylation Swiss-Prot 1010711 18669648 Q9Y5T5 552 S Phosphorylation Swiss-Prot 1010711 15302935;18669648;19413330;19690332 Q9Y5T5 554 T Phosphorylation Swiss-Prot 1010711 19413330 Q9Y5T5 415 S Phosphorylation PhosphoELM.10011 18669648 Q9Y5T5 552 S Phosphorylation PhosphoELM.10011 18669648;15302935 Q9Y5T5 554 T Phosphorylation PhosphoELM.10011 18669648 Q9Y5T5 293 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9Y5T5 37 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9Y5T5 426 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9Y5T5 199 S Phosphorylation Phosphositeplus.1010730 19690332 Q9Y5T5 415 S Phosphorylation Phosphositeplus.1010730 18669648;20166139;20393185;21406692;21659604;22115753 Q9Y5T5 551 S Phosphorylation Phosphositeplus.1010730 19690332;20058876 Q9Y5T5 552 S Phosphorylation Phosphositeplus.1010730 15302935;18669648;19664994;19690332;20058876;20068231;21659604 Q9Y5T5 550 T Phosphorylation Phosphositeplus.1010730 20058876 Q9Y5T5 554 T Phosphorylation Phosphositeplus.1010730 20068231 Q9Y5T5 415 S Phosphorylation HPRD 9.0 18669648,19651622,18452278,20166139 Q9Y5T5 551 S Phosphorylation HPRD 9.0 17322306,18669648,19413330,20068231,20058876 Q9Y5T5 551 S Phosphorylation HPRD 9.0 20068231,20058876 Q9Y5T5 552 S Phosphorylation HPRD 9.0 17322306,18669648,19413330,20068231,20058876 Q9Y5T5 145 T Phosphorylation HPRD 9.0 20068231 Q9Y5T5 550 T Phosphorylation HPRD 9.0 20058876 Q9Y5T5 554 T Phosphorylation HPRD 9.0 18669648,19413330,19651622,20068231 Q9Y5T5 600 T Phosphorylation HPRD 9.0 20068231 Q9Y5T5 415 S Phosphorylation SysPTM 1.1 18669648 Q9Y5T5 552 S Phosphorylation SysPTM 1.1 15302935;18669648

PTM - HPRD Symbol Position Code Type References USP16 145 T Phosphorylation 20068231 USP16 414 S Phosphorylation 18669648,19651622,18452278,20166139 USP16 415 S Phosphorylation 18669648,19651622,18452278,20166139 USP16 549 T Phosphorylation 20058876 USP16 550 S Phosphorylation 20068231,20058876 USP16 550 T Phosphorylation 20058876 USP16 551 S Phosphorylation 17322306,18669648,19413330,20068231,20058876 USP16 551 S Phosphorylation 20068231,20058876 USP16 552 S Phosphorylation 17322306,18669648,19413330,20068231,20058876 USP16 553 T Phosphorylation 18669648,19413330,19651622,20068231 USP16 554 T Phosphorylation 18669648,19413330,19651622,20068231 USP16 599 T Phosphorylation 20068231 USP16 600 T Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9Y5T5 415 S 18669648 HTP Phosphorylation Q9Y5T5 554 T 18669648 HTP Phosphorylation Q9Y5T5 552 S 18669648 HTP Phosphorylation Q9Y5T5 552 S 15302935 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9Y5T5 189 Phosphoserine 23186163 Q9Y5T5 415 Phosphoserine 18669648;21406692;23186163 Q9Y5T5 552 Phosphoserine 18669648;19690332;20068231;23186163 Q9Y5T5 554 Phosphothreonine 20068231

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type USP16 IPI00001780 S 551 DLEVLTpSSPTRNL phosphorylation USP16 IPI00001780 S 552 LEVLTSpSPTRNLN phosphorylation USP16 IPI00001780 T 554 VLTSSPpTRNLNGA phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 10600 115848 - K Ubiquitination 22118674 10600 115848 - K Ubiquitination 21139048 10600 115848 - K Ubiquitination 21890473 10600 115848 - K Ubiquitination 21906983 10600 115848 - K Ubiquitination 23287719 10600 115848 - K Ubiquitination 21963094 10600 115848 - K Ubiquitination 23000965 10600 115848 - K Ubiquitination 24816145

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID USP16 Homo sapiens (Human) 293; 37 "293,KKAVRFKGYQQQD; 37,LEQGNLKKALVNV" "293:21890473,21906983; 37:21906983" USP16 Homo sapiens (Human) 116 "116,DNDSYIKERSDIP" 116:21906983 USP16 Homo sapiens (Human) 411; 278; 23 "411,DNDSYIKERSDIP; 278,KKAVRFKGYQQQD; 23,LEQGNLKKALVNV" "411:21906983; 278:21890473,21906983; 23:21906983" USP16 Homo sapiens (Human) 425; 292; 37 "425,DNDSYIKERSDIP; 292,KKAVRFKGYQQQD; 37,LEQGNLKKALVNV" "425:21906983; 292:21890473,21906983; 37:21906983" USP16 Homo sapiens (Human) 426; 293; 37 "426,DNDSYIKERSDIP; 293,KKAVRFKGYQQQD; 37,LEQGNLKKALVNV" "426:21906983; 293:21906983,21890473; 37:21906983" USP16 Homo sapiens (Human) 292 "292,KKAVRFKGYQQQD" 292:21890473