Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 10 105110740 105110741 + In_Frame_Ins INS - - GGAGGC TCGA-OR-A5KB-01A-11D-A30A-10 TCGA-OR-A5KB-11A-11D-A30A-10 g.chr10:105110740_105110741insGGAGGC c.83_84insGCCTCC c.(82-84)cct>ccGCCTCCt p.28_28P>PPP BLCA 10 105110683 105110683 + Silent SNP A A C TCGA-G2-A2ES-01A-11D-A17V-08 TCGA-G2-A2ES-11A-31D-A17V-08 g.chr10:105110683A>C c.141T>G c.(139-141)ccT>ccG p.P47P BRCA 10 105073972 105073972 + Missense_Mutation SNP G G C TCGA-EW-A1OY-01A-11D-A142-09 TCGA-EW-A1OY-10A-01W-A187-09 g.chr10:105073972G>C c.967C>G c.(967-969)Cga>Gga p.R323G BRCA 10 105108721 105108721 + Missense_Mutation SNP G G C TCGA-PE-A5DE-01A-11D-A27P-09 TCGA-PE-A5DE-10A-01D-A27P-09 g.chr10:105108721G>C c.396C>G c.(394-396)atC>atG p.I132M BRCA 10 105110525 105110527 + In_Frame_Del DEL TCC TCC - TCGA-A7-A4SD-01A-11D-A25Q-09 TCGA-A7-A4SD-10A-01D-A25Q-09 g.chr10:105110525_105110527delTCC c.297_299delGGA c.(295-300)gaggac>gac p.E99del BRCA 10 105110755 105110756 + Frame_Shift_Del DEL CA CA - TCGA-LL-A50Y-01A-11D-A25Q-09 TCGA-LL-A50Y-10A-01D-A25Q-09 g.chr10:105110755_105110756delCA c.68_69delTG c.(67-69)ttgfs p.L23fs CESC 10 105107191 105107191 + Missense_Mutation SNP G G C TCGA-IR-A3LL-01A-11D-A20U-09 TCGA-IR-A3LL-10A-01D-A20U-09 g.chr10:105107191G>C c.574C>G c.(574-576)Caa>Gaa p.Q192E COAD 10 105086322 105086322 + Missense_Mutation SNP C C A TCGA-AZ-6600-01A-11D-1771-10 TCGA-AZ-6600-11A-01D-1771-10 g.chr10:105086322C>A c.878G>T c.(877-879)aGa>aTa p.R293I COAD 10 105110543 105110543 + Missense_Mutation SNP T T G TCGA-AA-3821-01A-01W-0995-10 TCGA-AA-3821-10A-01W-0995-10 g.chr10:105110543T>G c.281A>C c.(280-282)gAa>gCa p.E94A COADREAD 10 105086322 105086322 + Missense_Mutation SNP C C A TCGA-AZ-6600-01A-11D-1771-10 TCGA-AZ-6600-11A-01D-1771-10 g.chr10:105086322C>A c.878G>T c.(877-879)aGa>aTa p.R293I COADREAD 10 105086323 105086323 + Missense_Mutation SNP T T C TCGA-G5-6235-01A-11D-1733-10 TCGA-G5-6235-10A-01D-1733-10 g.chr10:105086323T>C c.877A>G c.(877-879)Aga>Gga p.R293G COADREAD 10 105110543 105110543 + Missense_Mutation SNP T T G TCGA-AA-3821-01A-01W-0995-10 TCGA-AA-3821-10A-01W-0995-10 g.chr10:105110543T>G c.281A>C c.(280-282)gAa>gCa p.E94A COADREAD 10 105110740 105110741 + In_Frame_Ins INS - - GGAGGC TCGA-CI-6622-01A-11D-1826-10 TCGA-CI-6622-10A-01D-1826-10 g.chr10:105110740_105110741insGGAGGC c.83_84insGCCTCC c.(82-84)cct>ccGCCTCCt p.28_28P>PPP ESCA 10 105110755 105110756 + Frame_Shift_Del DEL CA CA - TCGA-LN-A4A4-01A-11D-A27G-09 TCGA-LN-A4A4-10A-01D-A27G-09 g.chr10:105110755_105110756delCA c.68_69delTG c.(67-69)ttgfs p.L23fs ESCA 10 105110755 105110756 + Frame_Shift_Del DEL CA CA - TCGA-VR-A8EX-01A-11D-A36J-09 TCGA-VR-A8EX-10A-01D-A36M-09 g.chr10:105110755_105110756delCA c.68_69delTG c.(67-69)ttgfs p.L23fs GBM 10 105108477 105108477 + Missense_Mutation SNP T T C TCGA-14-0813-01A-01W-0424-08 TCGA-14-0813-10A-01W-0424-08 g.chr10:105108477T>C c.553A>G c.(553-555)Ata>Gta p.I185V GBMLGG 10 105086326 105086326 + Missense_Mutation SNP G G T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr10:105086326G>T c.874C>A c.(874-876)Ctc>Atc p.L292I GBMLGG 10 105108477 105108477 + Missense_Mutation SNP T T C TCGA-14-0813-01A-01W-0424-08 TCGA-14-0813-10A-01W-0424-08 g.chr10:105108477T>C c.553A>G c.(553-555)Ata>Gta p.I185V HNSC 10 105107010 105107010 + Missense_Mutation SNP C C G TCGA-CV-A45P-01A-11D-A24D-08 TCGA-CV-A45P-10A-01D-A24F-08 g.chr10:105107010C>G c.658G>C c.(658-660)Gaa>Caa p.E220Q KIPAN 10 105110747 105110747 + Missense_Mutation SNP G G T TCGA-BP-5006-01A-01D-1462-08 TCGA-BP-5006-11A-01D-1462-08 g.chr10:105110747G>T c.77C>A c.(76-78)cCg>cAg p.P26Q KIRC 10 105110747 105110747 + Missense_Mutation SNP G G T TCGA-BP-5006-01A-01D-1462-08 TCGA-BP-5006-11A-01D-1462-08 g.chr10:105110747G>T c.77C>A c.(76-78)cCg>cAg p.P26Q LGG 10 105086326 105086326 + Missense_Mutation SNP G G T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr10:105086326G>T c.874C>A c.(874-876)Ctc>Atc p.L292I LIHC 10 105104793 105104793 + Missense_Mutation SNP A A G TCGA-CC-A7IL-01A-11D-A33Q-10 TCGA-CC-A7IL-10A-01D-A33Q-10 g.chr10:105104793A>G c.770T>C c.(769-771)cTg>cCg p.L257P LIHC 10 105110543 105110543 + Missense_Mutation SNP T T C TCGA-BC-A3KG-01A-11D-A20W-10 TCGA-BC-A3KG-10A-01D-A20W-10 g.chr10:105110543T>C c.281A>G c.(280-282)gAa>gGa p.E94G LIHC 10 105110554 105110554 + Silent SNP C C T TCGA-3K-AAZ8-01A-12D-A38X-10 TCGA-3K-AAZ8-10A-01D-A38X-10 g.chr10:105110554C>T c.270G>A c.(268-270)ctG>ctA p.L90L LUAD 10 105108755 105108755 + Splice_Site SNP C C A TCGA-50-5936-01A-11D-1625-08 TCGA-50-5936-11A-01D-1625-08 g.chr10:105108755C>A c.362G>T c.(361-363)cGc>cTc p.R121L LUSC 10 105086378 105086378 + Missense_Mutation SNP C C G TCGA-60-2698-01A-01D-1522-08 TCGA-60-2698-11A-01D-1522-08 g.chr10:105086378C>G c.822G>C c.(820-822)aaG>aaC p.K274N LUSC 10 105110820 105110820 + Missense_Mutation SNP C C G TCGA-66-2785-01A-01D-1522-08 TCGA-66-2785-11A-01D-1522-08 g.chr10:105110820C>G c.4G>C c.(4-6)Gag>Cag p.E2Q PAAD 10 105063703 105063703 + Missense_Mutation SNP G G T TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr10:105063703G>T c.1012C>A c.(1012-1014)Ctt>Att p.L338I READ 10 105086323 105086323 + Missense_Mutation SNP T T C TCGA-G5-6235-01A-11D-1733-10 TCGA-G5-6235-10A-01D-1733-10 g.chr10:105086323T>C c.877A>G c.(877-879)Aga>Gga p.R293G READ 10 105110740 105110741 + In_Frame_Ins INS - - GGAGGC TCGA-CI-6622-01A-11D-1826-10 TCGA-CI-6622-10A-01D-1826-10 g.chr10:105110740_105110741insGGAGGC c.83_84insGCCTCC c.(82-84)cct>ccGCCTCCt p.28_28P>PPP SKCM 10 105104827 105104827 + Missense_Mutation SNP G G A TCGA-DA-A1I7-06A-22D-A197-08 TCGA-DA-A1I7-10A-01D-A199-08 g.chr10:105104827G>A c.736C>T c.(736-738)Cgt>Tgt p.R246C

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US 10 105110683 105110683 single base substitution A C exon_variant BLCA-US 10 105110683 105110683 single base substitution A C synonymous_variant P47P 141T>G BLCA-US 10 105110683 105110683 single base substitution A C upstream_gene_variant BRCA-EU 10 105058331 105058331 single base substitution G A downstream_gene_variant BRCA-EU 10 105058484 105058484 single base substitution C T downstream_gene_variant BRCA-EU 10 105058848 105058848 single base substitution C G downstream_gene_variant BRCA-EU 10 105060391 105060391 single base substitution C T downstream_gene_variant BRCA-EU 10 105062559 105062559 single base substitution A C 3_prime_UTR_variant BRCA-EU 10 105062559 105062559 single base substitution A C downstream_gene_variant BRCA-EU 10 105063732 105063732 deletion of <=200bp A - intron_variant BRCA-EU 10 105065279 105065279 single base substitution C T intron_variant BRCA-EU 10 105065640 105065640 single base substitution C G intron_variant BRCA-EU 10 105065772 105065772 single base substitution C G intron_variant BRCA-EU 10 105065830 105065830 single base substitution C A intron_variant BRCA-EU 10 105066801 105066813 deletion of <=200bp CAGTGAGCCAAGA - intron_variant BRCA-EU 10 105067482 105067482 single base substitution G C intron_variant BRCA-EU 10 105069725 105069725 single base substitution T G intron_variant BRCA-EU 10 105071411 105071411 single base substitution T G intron_variant BRCA-EU 10 105076398 105076398 single base substitution G A intron_variant BRCA-EU 10 105077070 105077070 single base substitution T C intron_variant BRCA-EU 10 105077481 105077481 single base substitution C T intron_variant BRCA-EU 10 105078445 105078445 single base substitution G A intron_variant BRCA-EU 10 105079809 105079809 single base substitution C T intron_variant BRCA-EU 10 105080147 105080147 insertion of <=200bp - T intron_variant BRCA-EU 10 105080313 105080313 single base substitution G A intron_variant BRCA-EU 10 105083708 105083708 deletion of <=200bp T - intron_variant BRCA-EU 10 105085787 105085787 deletion of <=200bp A - intron_variant BRCA-EU 10 105088582 105088582 single base substitution C T intron_variant BRCA-EU 10 105089225 105089225 single base substitution C A intron_variant BRCA-EU 10 105089268 105089268 single base substitution C A intron_variant BRCA-EU 10 105090767 105090767 single base substitution C G intron_variant BRCA-EU 10 105090837 105090837 single base substitution G A intron_variant BRCA-EU 10 105090988 105090988 single base substitution T C intron_variant BRCA-EU 10 105094455 105094456 deletion of <=200bp AC - intron_variant BRCA-EU 10 105095992 105096004 deletion of <=200bp AAAAAAAAAATTT - intron_variant BRCA-EU 10 105098161 105098161 single base substitution G A intron_variant BRCA-EU 10 105098257 105098257 single base substitution G A intron_variant BRCA-EU 10 105099684 105099684 single base substitution G T intron_variant BRCA-EU 10 105100930 105100930 single base substitution G A intron_variant BRCA-EU 10 105101315 105101315 single base substitution G T intron_variant BRCA-EU 10 105102615 105102615 single base substitution C T intron_variant BRCA-EU 10 105103849 105103849 single base substitution G T downstream_gene_variant BRCA-EU 10 105103849 105103849 single base substitution G T intron_variant BRCA-EU 10 105105499 105105499 single base substitution C A downstream_gene_variant BRCA-EU 10 105105499 105105499 single base substitution C A intron_variant BRCA-EU 10 105106812 105106812 single base substitution G A downstream_gene_variant BRCA-EU 10 105106812 105106812 single base substitution G A intron_variant BRCA-EU 10 105107816 105107816 single base substitution G C downstream_gene_variant BRCA-EU 10 105107816 105107816 single base substitution G C intron_variant BRCA-EU 10 105108524 105108524 single base substitution C T exon_variant BRCA-EU 10 105108524 105108524 single base substitution C T missense_variant C169Y 506G>A BRCA-EU 10 105109779 105109779 single base substitution G A intron_variant BRCA-EU 10 105109779 105109779 single base substitution G A upstream_gene_variant BRCA-EU 10 105109994 105109994 single base substitution G T intron_variant BRCA-EU 10 105109994 105109994 single base substitution G T upstream_gene_variant BRCA-EU 10 105110159 105110159 single base substitution G A intron_variant BRCA-EU 10 105110159 105110159 single base substitution G A upstream_gene_variant BRCA-EU 10 105111702 105111702 single base substitution G A upstream_gene_variant BRCA-EU 10 105112386 105112386 single base substitution G A upstream_gene_variant BRCA-EU 10 105112739 105112739 single base substitution G A upstream_gene_variant BRCA-EU 10 105114733 105114733 single base substitution G C upstream_gene_variant BRCA-FR 10 105058484 105058484 single base substitution C T downstream_gene_variant BRCA-FR 10 105072495 105072495 single base substitution G T intron_variant BRCA-FR 10 105077070 105077070 single base substitution T C intron_variant BRCA-FR 10 105090988 105090988 single base substitution T C intron_variant BRCA-FR 10 105091259 105091259 single base substitution C T intron_variant BRCA-FR 10 105099684 105099684 single base substitution G T intron_variant BRCA-FR 10 105101980 105101980 single base substitution T C intron_variant BRCA-FR 10 105102615 105102615 single base substitution C T intron_variant BRCA-FR 10 105107816 105107816 single base substitution G C downstream_gene_variant BRCA-FR 10 105107816 105107816 single base substitution G C intron_variant BRCA-FR 10 105109994 105109994 single base substitution G T intron_variant BRCA-FR 10 105109994 105109994 single base substitution G T upstream_gene_variant BRCA-FR 10 105111702 105111702 single base substitution G A upstream_gene_variant BRCA-FR 10 105113773 105113773 single base substitution C A upstream_gene_variant BRCA-UK 10 105058331 105058331 single base substitution G A downstream_gene_variant BRCA-UK 10 105102708 105102708 single base substitution G C intron_variant BRCA-US 10 105073972 105073972 single base substitution G C exon_variant BRCA-US 10 105073972 105073972 single base substitution G C missense_variant R248G 742C>G BRCA-US 10 105073972 105073972 single base substitution G C missense_variant R323G 967C>G BRCA-US 10 105107077 105107077 single base substitution C G downstream_gene_variant BRCA-US 10 105107077 105107077 single base substitution C G intron_variant BRCA-US 10 105107077 105107077 single base substitution C G splice_acceptor_variant BRCA-US 10 105110525 105110527 deletion of <=200bp TCC - disruptive_inframe_deletion ED99D BRCA-US 10 105110525 105110527 deletion of <=200bp TCC - exon_variant BRCA-US 10 105110525 105110527 deletion of <=200bp TCC - upstream_gene_variant BRCA-US 10 105110755 105110756 deletion of <=200bp CA - exon_variant BRCA-US 10 105110755 105110756 deletion of <=200bp CA - frameshift_variant L23 BRCA-US 10 105110755 105110756 deletion of <=200bp CA - upstream_gene_variant CESC-US 10 105107191 105107191 single base substitution G C downstream_gene_variant CESC-US 10 105107191 105107191 single base substitution G C exon_variant CESC-US 10 105107191 105107191 single base substitution G C intron_variant CESC-US 10 105107191 105107191 single base substitution G C missense_variant Q192E 574C>G CLLE-ES 10 105084560 105084560 single base substitution T A intron_variant CLLE-ES 10 105107889 105107889 single base substitution A G downstream_gene_variant CLLE-ES 10 105107889 105107889 single base substitution A G intron_variant COAD-US 10 105110740 105110740 insertion of <=200bp - GGAGGC exon_variant COAD-US 10 105110740 105110740 insertion of <=200bp - GGAGGC inframe_insertion P28PAS COAD-US 10 105110740 105110740 insertion of <=200bp - GGAGGC upstream_gene_variant COCA-CN 10 105063796 105063796 single base substitution A G intron_variant COCA-CN 10 105063868 105063868 single base substitution T G intron_variant COCA-CN 10 105063912 105063912 single base substitution G T intron_variant COCA-CN 10 105073968 105073968 single base substitution C T exon_variant COCA-CN 10 105073968 105073968 single base substitution C T missense_variant R249H 746G>A COCA-CN 10 105073968 105073968 single base substitution C T missense_variant R324H 971G>A COCA-CN 10 105074057 105074057 single base substitution G T intron_variant COCA-CN 10 105075768 105075768 single base substitution T G intron_variant COCA-CN 10 105075770 105075770 single base substitution T G intron_variant COCA-CN 10 105077742 105077742 single base substitution G A intron_variant COCA-CN 10 105086409 105086409 single base substitution A C intron_variant COCA-CN 10 105086450 105086450 single base substitution A G intron_variant COCA-CN 10 105086497 105086497 single base substitution G A intron_variant COCA-CN 10 105088472 105088472 single base substitution C A intron_variant COCA-CN 10 105088599 105088599 single base substitution T C intron_variant COCA-CN 10 105108553 105108553 single base substitution G A exon_variant COCA-CN 10 105108553 105108553 single base substitution G A synonymous_variant I159I 477C>T EOPC-DE 10 105073993 105073993 single base substitution A G exon_variant EOPC-DE 10 105073993 105073993 single base substitution A G missense_variant Y241H 721T>C EOPC-DE 10 105073993 105073993 single base substitution A G missense_variant Y316H 946T>C ESAD-UK 10 105062645 105062645 single base substitution G C 3_prime_UTR_variant ESAD-UK 10 105062645 105062645 single base substitution G C downstream_gene_variant ESAD-UK 10 105063882 105063882 single base substitution C T intron_variant ESAD-UK 10 105065994 105065994 single base substitution A T intron_variant ESAD-UK 10 105067087 105067087 single base substitution G A intron_variant ESAD-UK 10 105069049 105069049 single base substitution G C intron_variant ESAD-UK 10 105070556 105070556 single base substitution C G intron_variant ESAD-UK 10 105070779 105070779 single base substitution G C intron_variant ESAD-UK 10 105073555 105073555 single base substitution C T intron_variant ESAD-UK 10 105074217 105074217 single base substitution A G intron_variant ESAD-UK 10 105075053 105075053 single base substitution C T intron_variant ESAD-UK 10 105075461 105075461 single base substitution G A intron_variant ESAD-UK 10 105075908 105075908 single base substitution T C intron_variant ESAD-UK 10 105078976 105078976 single base substitution G A intron_variant ESAD-UK 10 105080086 105080086 single base substitution G A intron_variant ESAD-UK 10 105081124 105081124 single base substitution T C intron_variant ESAD-UK 10 105085362 105085362 single base substitution C T intron_variant ESAD-UK 10 105087906 105087906 single base substitution A G intron_variant ESAD-UK 10 105087968 105087968 deletion of <=200bp T - intron_variant ESAD-UK 10 105088828 105088828 single base substitution G A intron_variant ESAD-UK 10 105090482 105090482 single base substitution C T intron_variant ESAD-UK 10 105091719 105091719 single base substitution T G intron_variant ESAD-UK 10 105092694 105092694 single base substitution A G intron_variant ESAD-UK 10 105098096 105098096 single base substitution C T intron_variant ESAD-UK 10 105100650 105100650 single base substitution A G intron_variant ESAD-UK 10 105105374 105105374 single base substitution C A downstream_gene_variant ESAD-UK 10 105105374 105105374 single base substitution C A intron_variant ESAD-UK 10 105105941 105105941 single base substitution G A downstream_gene_variant ESAD-UK 10 105105941 105105941 single base substitution G A intron_variant ESAD-UK 10 105106874 105106874 single base substitution T C downstream_gene_variant ESAD-UK 10 105106874 105106874 single base substitution T C intron_variant ESAD-UK 10 105111684 105111684 single base substitution G A upstream_gene_variant ESAD-UK 10 105111847 105111847 single base substitution G A upstream_gene_variant ESAD-UK 10 105112827 105112827 single base substitution G A upstream_gene_variant ESAD-UK 10 105114402 105114402 single base substitution A G upstream_gene_variant ESAD-UK 10 105114743 105114743 single base substitution G C upstream_gene_variant GBM-US 10 105108477 105108477 single base substitution T C exon_variant GBM-US 10 105108477 105108477 single base substitution T C missense_variant I185V 553A>G KIRC-US 10 105110747 105110747 single base substitution G T exon_variant KIRC-US 10 105110747 105110747 single base substitution G T missense_variant P26Q 77C>A KIRC-US 10 105110747 105110747 single base substitution G T upstream_gene_variant LAML-KR 10 105064430 105064430 single base substitution G T intron_variant LAML-KR 10 105071818 105071818 single base substitution G T intron_variant LAML-KR 10 105071835 105071835 single base substitution T C intron_variant LAML-KR 10 105089519 105089519 single base substitution C T intron_variant LAML-KR 10 105104047 105104047 single base substitution G T downstream_gene_variant LAML-KR 10 105104047 105104047 single base substitution G T intron_variant LICA-FR 10 105061332 105061332 insertion of <=200bp - A downstream_gene_variant LICA-FR 10 105073951 105073951 single base substitution C T exon_variant LICA-FR 10 105073951 105073951 single base substitution C T missense_variant A255T 763G>A LICA-FR 10 105073951 105073951 single base substitution C T missense_variant A330T 988G>A LICA-FR 10 105075740 105075740 single base substitution T G intron_variant LICA-FR 10 105095063 105095063 single base substitution A T intron_variant LICA-FR 10 105113480 105113481 deletion of <=200bp TT - upstream_gene_variant LIHC-US 10 105104793 105104793 single base substitution A G downstream_gene_variant LIHC-US 10 105104793 105104793 single base substitution A G exon_variant LIHC-US 10 105104793 105104793 single base substitution A G intron_variant LIHC-US 10 105104793 105104793 single base substitution A G missense_variant L257P 770T>C LINC-JP 10 105060441 105060441 single base substitution G T downstream_gene_variant LINC-JP 10 105072812 105072812 single base substitution T G intron_variant LINC-JP 10 105075180 105075180 single base substitution A C intron_variant LINC-JP 10 105084591 105084591 deletion of <=200bp A - intron_variant LINC-JP 10 105086164 105086164 deletion of <=200bp C - intron_variant LINC-JP 10 105087746 105087746 single base substitution T C intron_variant LINC-JP 10 105097835 105097835 single base substitution A C intron_variant LINC-JP 10 105097836 105097836 single base substitution A T intron_variant LINC-JP 10 105102136 105102136 single base substitution A C intron_variant LINC-JP 10 105102635 105102635 single base substitution T C intron_variant LINC-JP 10 105107968 105107968 single base substitution A T downstream_gene_variant LINC-JP 10 105107968 105107968 single base substitution A T intron_variant LIRI-JP 10 105057735 105057735 single base substitution T A downstream_gene_variant LIRI-JP 10 105059215 105059215 single base substitution T C downstream_gene_variant LIRI-JP 10 105059352 105059352 single base substitution T A downstream_gene_variant LIRI-JP 10 105059518 105059518 single base substitution A G downstream_gene_variant LIRI-JP 10 105061151 105061151 single base substitution G T downstream_gene_variant LIRI-JP 10 105062015 105062015 single base substitution G T downstream_gene_variant LIRI-JP 10 105065313 105065313 single base substitution C A intron_variant LIRI-JP 10 105066080 105066080 single base substitution C A intron_variant LIRI-JP 10 105066604 105066604 single base substitution T C intron_variant LIRI-JP 10 105066785 105066785 single base substitution T A intron_variant LIRI-JP 10 105067534 105067534 single base substitution T C intron_variant LIRI-JP 10 105067553 105067553 single base substitution A C intron_variant LIRI-JP 10 105076232 105076232 single base substitution T A intron_variant LIRI-JP 10 105077000 105077000 single base substitution T C intron_variant LIRI-JP 10 105083253 105083253 single base substitution T C intron_variant LIRI-JP 10 105087523 105087523 single base substitution C G intron_variant LIRI-JP 10 105096103 105096103 single base substitution T C intron_variant LIRI-JP 10 105098018 105098018 single base substitution C T intron_variant LIRI-JP 10 105098792 105098792 single base substitution A C intron_variant LIRI-JP 10 105100717 105100717 single base substitution T C intron_variant LIRI-JP 10 105100840 105100840 single base substitution G A intron_variant LIRI-JP 10 105102283 105102283 single base substitution G A intron_variant LIRI-JP 10 105104648 105104648 single base substitution T C downstream_gene_variant LIRI-JP 10 105104648 105104648 single base substitution T C intron_variant LIRI-JP 10 105104988 105104988 single base substitution T C downstream_gene_variant LIRI-JP 10 105104988 105104988 single base substitution T C intron_variant LIRI-JP 10 105105925 105105925 single base substitution C T downstream_gene_variant LIRI-JP 10 105105925 105105925 single base substitution C T intron_variant LIRI-JP 10 105107278 105107278 single base substitution T C downstream_gene_variant LIRI-JP 10 105107278 105107278 single base substitution T C intron_variant LIRI-JP 10 105110292 105110292 single base substitution G A intron_variant LIRI-JP 10 105110292 105110292 single base substitution G A upstream_gene_variant LIRI-JP 10 105110293 105110293 single base substitution G A intron_variant LIRI-JP 10 105110293 105110293 single base substitution G A upstream_gene_variant LIRI-JP 10 105115590 105115590 single base substitution G A upstream_gene_variant LUSC-KR 10 105058353 105058353 single base substitution G A downstream_gene_variant LUSC-KR 10 105062969 105062969 single base substitution A G 3_prime_UTR_variant LUSC-KR 10 105062969 105062969 single base substitution A G exon_variant LUSC-KR 10 105074766 105074766 single base substitution A G intron_variant LUSC-KR 10 105081417 105081417 single base substitution C A intron_variant LUSC-KR 10 105083657 105083657 single base substitution A G intron_variant LUSC-KR 10 105088233 105088233 single base substitution C A intron_variant LUSC-KR 10 105088643 105088643 single base substitution G T intron_variant LUSC-KR 10 105101869 105101869 single base substitution T A intron_variant LUSC-KR 10 105106680 105106680 single base substitution C A downstream_gene_variant LUSC-KR 10 105106680 105106680 single base substitution C A intron_variant LUSC-KR 10 105107329 105107329 single base substitution T A downstream_gene_variant LUSC-KR 10 105107329 105107329 single base substitution T A intron_variant LUSC-KR 10 105110980 105110980 single base substitution C G upstream_gene_variant LUSC-KR 10 105113119 105113119 single base substitution G A upstream_gene_variant LUSC-US 10 105086378 105086378 single base substitution C G exon_variant LUSC-US 10 105086378 105086378 single base substitution C G missense_variant K199N 597G>C LUSC-US 10 105086378 105086378 single base substitution C G missense_variant K274N 822G>C LUSC-US 10 105110820 105110820 single base substitution C G exon_variant LUSC-US 10 105110820 105110820 single base substitution C G missense_variant E2Q 4G>C LUSC-US 10 105110820 105110820 single base substitution C G upstream_gene_variant MALY-DE 10 105058216 105058216 single base substitution G C downstream_gene_variant MALY-DE 10 105071540 105071540 single base substitution T C intron_variant MALY-DE 10 105077442 105077442 single base substitution A T intron_variant MALY-DE 10 105093336 105093336 single base substitution G A intron_variant MALY-DE 10 105099024 105099024 single base substitution A G intron_variant MALY-DE 10 105099026 105099026 single base substitution A G intron_variant MALY-DE 10 105100131 105100131 single base substitution T C intron_variant MALY-DE 10 105109833 105109833 deletion of <=200bp C - intron_variant MALY-DE 10 105109833 105109833 deletion of <=200bp C - upstream_gene_variant MALY-DE 10 105114238 105114238 single base substitution G T upstream_gene_variant MELA-AU 10 105057987 105057987 single base substitution A T downstream_gene_variant MELA-AU 10 105057993 105057993 single base substitution G A downstream_gene_variant MELA-AU 10 105058539 105058539 single base substitution G A downstream_gene_variant MELA-AU 10 105058549 105058549 single base substitution G A downstream_gene_variant MELA-AU 10 105058639 105058639 single base substitution C T downstream_gene_variant MELA-AU 10 105058988 105058988 single base substitution T A downstream_gene_variant MELA-AU 10 105058990 105058990 single base substitution A T downstream_gene_variant MELA-AU 10 105059295 105059296 multiple base substitution (>=2bp and <=200bp) GG AA downstream_gene_variant MELA-AU 10 105059296 105059296 single base substitution G A downstream_gene_variant MELA-AU 10 105059933 105059933 single base substitution C T downstream_gene_variant MELA-AU 10 105059984 105059984 single base substitution G A downstream_gene_variant MELA-AU 10 105060177 105060177 single base substitution G A downstream_gene_variant MELA-AU 10 105060249 105060249 single base substitution C T downstream_gene_variant MELA-AU 10 105060388 105060388 single base substitution G A downstream_gene_variant MELA-AU 10 105060441 105060441 single base substitution G A downstream_gene_variant MELA-AU 10 105060584 105060584 single base substitution G A downstream_gene_variant MELA-AU 10 105061908 105061908 single base substitution C T downstream_gene_variant MELA-AU 10 105063729 105063729 single base substitution G A intron_variant MELA-AU 10 105064323 105064323 single base substitution C T intron_variant MELA-AU 10 105064938 105064938 single base substitution C T intron_variant MELA-AU 10 105066550 105066550 single base substitution G C intron_variant MELA-AU 10 105067108 105067108 single base substitution T C intron_variant MELA-AU 10 105067500 105067500 single base substitution G A intron_variant MELA-AU 10 105067716 105067716 single base substitution G A intron_variant MELA-AU 10 105067872 105067873 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 10 105068136 105068136 single base substitution G A intron_variant MELA-AU 10 105068667 105068667 single base substitution A T intron_variant MELA-AU 10 105068967 105068967 single base substitution G A intron_variant MELA-AU 10 105069074 105069074 single base substitution G C intron_variant MELA-AU 10 105069075 105069075 single base substitution G A intron_variant MELA-AU 10 105071021 105071021 single base substitution C T intron_variant MELA-AU 10 105071667 105071667 single base substitution G A intron_variant MELA-AU 10 105072712 105072712 single base substitution C T intron_variant MELA-AU 10 105073001 105073001 single base substitution G A intron_variant MELA-AU 10 105073427 105073427 single base substitution C T intron_variant MELA-AU 10 105074227 105074227 single base substitution G A intron_variant MELA-AU 10 105074358 105074358 single base substitution G A intron_variant MELA-AU 10 105074428 105074428 single base substitution C G intron_variant MELA-AU 10 105074937 105074937 single base substitution C T intron_variant MELA-AU 10 105075412 105075412 single base substitution G A intron_variant MELA-AU 10 105075772 105075772 single base substitution G T intron_variant MELA-AU 10 105076592 105076592 single base substitution T A intron_variant MELA-AU 10 105076911 105076911 single base substitution G A intron_variant MELA-AU 10 105077665 105077665 single base substitution A G intron_variant MELA-AU 10 105078490 105078490 single base substitution G A intron_variant MELA-AU 10 105078873 105078873 single base substitution C G intron_variant MELA-AU 10 105081670 105081670 single base substitution T G intron_variant MELA-AU 10 105082959 105082959 single base substitution G A intron_variant MELA-AU 10 105083189 105083189 single base substitution G A intron_variant MELA-AU 10 105083413 105083413 single base substitution G A intron_variant MELA-AU 10 105084785 105084785 single base substitution G A intron_variant MELA-AU 10 105086368 105086368 single base substitution G A exon_variant MELA-AU 10 105086368 105086368 single base substitution G A stop_gained R203* 607C>T MELA-AU 10 105086368 105086368 single base substitution G A stop_gained R278* 832C>T MELA-AU 10 105088533 105088533 single base substitution G A intron_variant MELA-AU 10 105088931 105088931 single base substitution G A intron_variant MELA-AU 10 105089994 105089994 single base substitution G A intron_variant MELA-AU 10 105090104 105090104 single base substitution T A intron_variant MELA-AU 10 105091073 105091073 single base substitution G T intron_variant MELA-AU 10 105091150 105091150 single base substitution G A intron_variant MELA-AU 10 105091270 105091270 single base substitution C T intron_variant MELA-AU 10 105091683 105091683 single base substitution G A intron_variant MELA-AU 10 105092448 105092448 single base substitution G A intron_variant MELA-AU 10 105093095 105093095 single base substitution G A intron_variant MELA-AU 10 105094010 105094010 single base substitution G A intron_variant MELA-AU 10 105095005 105095005 single base substitution C T intron_variant MELA-AU 10 105095340 105095340 single base substitution G A intron_variant MELA-AU 10 105098197 105098197 single base substitution G A intron_variant MELA-AU 10 105099531 105099531 single base substitution G A intron_variant MELA-AU 10 105100023 105100023 single base substitution G C intron_variant MELA-AU 10 105101290 105101290 single base substitution G A intron_variant MELA-AU 10 105101426 105101426 single base substitution C T intron_variant MELA-AU 10 105102261 105102261 single base substitution G A intron_variant MELA-AU 10 105102620 105102620 single base substitution G A intron_variant MELA-AU 10 105102678 105102678 single base substitution C G intron_variant MELA-AU 10 105104359 105104359 single base substitution G C downstream_gene_variant MELA-AU 10 105104359 105104359 single base substitution G C intron_variant MELA-AU 10 105104842 105104842 single base substitution G A downstream_gene_variant MELA-AU 10 105104842 105104842 single base substitution G A exon_variant MELA-AU 10 105104842 105104842 single base substitution G A intron_variant MELA-AU 10 105104842 105104842 single base substitution G A synonymous_variant L241L 721C>T MELA-AU 10 105104952 105104952 single base substitution G A downstream_gene_variant MELA-AU 10 105104952 105104952 single base substitution G A intron_variant MELA-AU 10 105105590 105105590 single base substitution A C downstream_gene_variant MELA-AU 10 105105590 105105590 single base substitution A C intron_variant MELA-AU 10 105106165 105106165 single base substitution G A downstream_gene_variant MELA-AU 10 105106165 105106165 single base substitution G A intron_variant MELA-AU 10 105108334 105108334 single base substitution G A exon_variant MELA-AU 10 105108334 105108334 single base substitution G A intron_variant MELA-AU 10 105109683 105109683 single base substitution C G intron_variant MELA-AU 10 105109683 105109683 single base substitution C G upstream_gene_variant MELA-AU 10 105112977 105112977 single base substitution G A upstream_gene_variant MELA-AU 10 105112988 105112988 single base substitution G A upstream_gene_variant MELA-AU 10 105113669 105113669 single base substitution C T upstream_gene_variant MELA-AU 10 105115258 105115258 single base substitution G A upstream_gene_variant ORCA-IN 10 105098418 105098418 single base substitution G A intron_variant OV-AU 10 105059819 105059819 single base substitution G T downstream_gene_variant OV-AU 10 105060170 105060170 single base substitution C T downstream_gene_variant OV-AU 10 105060694 105060694 single base substitution T A downstream_gene_variant OV-AU 10 105068091 105068091 single base substitution C A intron_variant OV-AU 10 105074699 105074699 single base substitution G C intron_variant OV-AU 10 105078941 105078941 single base substitution C G intron_variant OV-AU 10 105088395 105088395 single base substitution A C intron_variant OV-AU 10 105090780 105090780 single base substitution C T intron_variant OV-AU 10 105093093 105093093 single base substitution C A intron_variant OV-AU 10 105095573 105095573 single base substitution A C intron_variant OV-AU 10 105100982 105100982 single base substitution G A intron_variant OV-AU 10 105102848 105102848 single base substitution G C intron_variant OV-AU 10 105102868 105102868 single base substitution G C intron_variant OV-AU 10 105104261 105104261 single base substitution G A downstream_gene_variant OV-AU 10 105104261 105104261 single base substitution G A intron_variant PACA-AU 10 105058176 105058176 single base substitution C T downstream_gene_variant PACA-AU 10 105060521 105060521 single base substitution C T downstream_gene_variant PACA-AU 10 105063805 105063805 single base substitution T A intron_variant PACA-AU 10 105083115 105083115 single base substitution G A intron_variant PACA-AU 10 105084418 105084418 single base substitution G A intron_variant PACA-AU 10 105093040 105093040 single base substitution A G intron_variant PACA-AU 10 105108552 105108552 single base substitution C T exon_variant PACA-AU 10 105108552 105108552 single base substitution C T missense_variant V160I 478G>A PACA-AU 10 105111735 105111735 single base substitution C T upstream_gene_variant PACA-AU 10 105113590 105113590 single base substitution C T upstream_gene_variant PACA-CA 10 105058965 105058965 single base substitution G A downstream_gene_variant PACA-CA 10 105060430 105060430 single base substitution C T downstream_gene_variant PACA-CA 10 105060625 105060625 single base substitution C T downstream_gene_variant PACA-CA 10 105060667 105060668 deletion of <=200bp CT - downstream_gene_variant PACA-CA 10 105065434 105065434 single base substitution T G intron_variant PACA-CA 10 105069020 105069020 single base substitution G A intron_variant PACA-CA 10 105069833 105069833 single base substitution G A intron_variant PACA-CA 10 105071016 105071016 single base substitution A C intron_variant PACA-CA 10 105075736 105075736 deletion of <=200bp T - intron_variant PACA-CA 10 105075738 105075740 deletion of <=200bp TGT - intron_variant PACA-CA 10 105079157 105079157 single base substitution C A intron_variant PACA-CA 10 105082058 105082058 single base substitution A G intron_variant PACA-CA 10 105086291 105086291 single base substitution C A missense_variant Q228H 684G>T PACA-CA 10 105086291 105086291 single base substitution C A missense_variant Q303H 909G>T PACA-CA 10 105086291 105086291 single base substitution C A splice_region_variant PACA-CA 10 105090878 105090878 single base substitution C T intron_variant PACA-CA 10 105092098 105092098 single base substitution G A intron_variant PACA-CA 10 105096005 105096005 single base substitution A T intron_variant PACA-CA 10 105098362 105098362 single base substitution G A intron_variant PACA-CA 10 105098621 105098621 single base substitution G A intron_variant PACA-CA 10 105109482 105109482 single base substitution G A intron_variant PACA-CA 10 105109482 105109482 single base substitution G A upstream_gene_variant PACA-CA 10 105113086 105113086 single base substitution G A upstream_gene_variant PACA-CA 10 105114186 105114186 single base substitution T C upstream_gene_variant PAEN-AU 10 105064318 105064318 single base substitution G C intron_variant PAEN-AU 10 105096678 105096678 single base substitution C T intron_variant PBCA-DE 10 105059711 105059711 single base substitution A T downstream_gene_variant PBCA-DE 10 105062602 105062602 single base substitution T A 3_prime_UTR_variant PBCA-DE 10 105062602 105062602 single base substitution T A downstream_gene_variant PBCA-DE 10 105072717 105072717 insertion of <=200bp - CAAAAA intron_variant PBCA-DE 10 105080118 105080118 single base substitution T A intron_variant PBCA-DE 10 105095593 105095593 insertion of <=200bp - GT intron_variant PBCA-DE 10 105110267 105110267 deletion of <=200bp G - intron_variant PBCA-DE 10 105110267 105110267 deletion of <=200bp G - upstream_gene_variant PBCA-DE 10 105111545 105111545 single base substitution G A upstream_gene_variant PRAD-CA 10 105075772 105075772 single base substitution G T intron_variant PRAD-CA 10 105075774 105075774 single base substitution G T intron_variant PRAD-UK 10 105057948 105057948 single base substitution A G downstream_gene_variant PRAD-UK 10 105058213 105058213 single base substitution A G downstream_gene_variant PRAD-UK 10 105062918 105062918 single base substitution C T 3_prime_UTR_variant PRAD-UK 10 105062918 105062918 single base substitution C T exon_variant PRAD-UK 10 105070066 105070066 single base substitution G C intron_variant PRAD-UK 10 105078462 105078462 single base substitution C A intron_variant PRAD-UK 10 105094433 105094433 single base substitution T A intron_variant PRAD-UK 10 105107344 105107344 single base substitution G C downstream_gene_variant PRAD-UK 10 105107344 105107344 single base substitution G C intron_variant PRAD-UK 10 105109426 105109426 single base substitution A G intron_variant PRAD-UK 10 105109426 105109426 single base substitution A G upstream_gene_variant PRAD-UK 10 105112566 105112566 single base substitution G A upstream_gene_variant PRAD-UK 10 105113556 105113556 single base substitution C T upstream_gene_variant PRAD-UK 10 105115638 105115638 single base substitution G A upstream_gene_variant READ-US 10 105073999 105073999 single base substitution C G exon_variant READ-US 10 105073999 105073999 single base substitution C G missense_variant E239Q 715G>C READ-US 10 105073999 105073999 single base substitution C G missense_variant E314Q 940G>C READ-US 10 105110740 105110740 insertion of <=200bp - GGAGGC exon_variant READ-US 10 105110740 105110740 insertion of <=200bp - GGAGGC inframe_insertion P28PAS READ-US 10 105110740 105110740 insertion of <=200bp - GGAGGC upstream_gene_variant RECA-EU 10 105069373 105069373 single base substitution C T intron_variant RECA-EU 10 105094166 105094166 single base substitution T C intron_variant RECA-EU 10 105108261 105108261 single base substitution T A exon_variant RECA-EU 10 105108261 105108261 single base substitution T A intron_variant RECA-EU 10 105111834 105111834 single base substitution T A upstream_gene_variant SKCA-BR 10 105057627 105057627 single base substitution C T downstream_gene_variant SKCA-BR 10 105058389 105058389 single base substitution C T downstream_gene_variant SKCA-BR 10 105059384 105059387 deletion of <=200bp CAAA - downstream_gene_variant SKCA-BR 10 105063137 105063163 deletion of <=200bp TATAAAAAAAGGTACAAGTTCAAAATA - 3_prime_UTR_variant SKCA-BR 10 105063137 105063163 deletion of <=200bp TATAAAAAAAGGTACAAGTTCAAAATA - exon_variant SKCA-BR 10 105063519 105063519 single base substitution C T 3_prime_UTR_variant SKCA-BR 10 105063519 105063519 single base substitution C T exon_variant SKCA-BR 10 105063897 105063897 insertion of <=200bp - CT intron_variant SKCA-BR 10 105065845 105065845 insertion of <=200bp - CA intron_variant SKCA-BR 10 105065860 105065860 single base substitution T C intron_variant SKCA-BR 10 105069711 105069711 insertion of <=200bp - CTT intron_variant SKCA-BR 10 105073374 105073374 insertion of <=200bp - GA intron_variant SKCA-BR 10 105075725 105075729 deletion of <=200bp ATGTG - intron_variant SKCA-BR 10 105075740 105075740 single base substitution T G intron_variant SKCA-BR 10 105075770 105075770 single base substitution T G intron_variant SKCA-BR 10 105075772 105075772 single base substitution G T intron_variant SKCA-BR 10 105077384 105077384 single base substitution G A intron_variant SKCA-BR 10 105079897 105079897 single base substitution G A intron_variant SKCA-BR 10 105083168 105083168 single base substitution C T intron_variant SKCA-BR 10 105084899 105084899 insertion of <=200bp - TAAATA intron_variant SKCA-BR 10 105084899 105084904 deletion of <=200bp TAAATA - intron_variant SKCA-BR 10 105087561 105087561 single base substitution A T intron_variant SKCA-BR 10 105091104 105091104 single base substitution C T intron_variant SKCA-BR 10 105092164 105092164 single base substitution G A intron_variant SKCA-BR 10 105092302 105092302 single base substitution G A intron_variant SKCA-BR 10 105092858 105092858 single base substitution A C intron_variant SKCA-BR 10 105094973 105094973 insertion of <=200bp - TA intron_variant SKCA-BR 10 105095387 105095387 single base substitution G A intron_variant SKCA-BR 10 105098278 105098278 single base substitution G A intron_variant SKCA-BR 10 105099937 105099938 deletion of <=200bp GA - intron_variant SKCA-BR 10 105099953 105099957 deletion of <=200bp AAAAT - intron_variant SKCA-BR 10 105100357 105100357 insertion of <=200bp - AT intron_variant SKCA-BR 10 105101220 105101220 single base substitution G A intron_variant SKCA-BR 10 105101360 105101360 insertion of <=200bp - CT intron_variant SKCA-BR 10 105102725 105102725 single base substitution G C intron_variant SKCA-BR 10 105106151 105106151 single base substitution G A downstream_gene_variant SKCA-BR 10 105106151 105106151 single base substitution G A intron_variant SKCA-BR 10 105108097 105108098 deletion of <=200bp GT - downstream_gene_variant SKCA-BR 10 105108097 105108098 deletion of <=200bp GT - intron_variant SKCA-BR 10 105109236 105109236 insertion of <=200bp - GT intron_variant SKCA-BR 10 105109236 105109236 insertion of <=200bp - GT upstream_gene_variant SKCA-BR 10 105112831 105112831 single base substitution C T upstream_gene_variant SKCA-BR 10 105112832 105112832 single base substitution C T upstream_gene_variant SKCA-BR 10 105115891 105115891 single base substitution A T upstream_gene_variant SKCM-US 10 105104827 105104827 single base substitution G A downstream_gene_variant SKCM-US 10 105104827 105104827 single base substitution G A exon_variant SKCM-US 10 105104827 105104827 single base substitution G A intron_variant SKCM-US 10 105104827 105104827 single base substitution G A missense_variant R246C 736C>T STAD-US 10 105108736 105108736 single base substitution C G exon_variant STAD-US 10 105108736 105108736 single base substitution C G missense_variant E127D 381G>C STAD-US 10 105108736 105108736 single base substitution C G upstream_gene_variant UCEC-US 10 105108756 105108756 single base substitution G A missense_variant R121C 361C>T UCEC-US 10 105108756 105108756 single base substitution G A splice_region_variant UCEC-US 10 105108756 105108756 single base substitution G A upstream_gene_variant UCEC-US 10 105110561 105110563 deletion of <=200bp TCT - disruptive_inframe_deletion EE87E UCEC-US 10 105110561 105110563 deletion of <=200bp TCT - exon_variant UCEC-US 10 105110561 105110563 deletion of <=200bp TCT - upstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand CCK81 COSM2059751 c.388C>G p.P130A Substitution - Missense 10:103348972-103348972 - LUAD-5V8LT COSM401104 c.167G>T p.C56F Substitution - Missense 10:103350900-103350900 - TCGA-D5-7000-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - WSU-HN12 COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - TCGA-LL-A50Y-01 COSM5831382 c.68_69delTG p.L23fs*19 Deletion - Frameshift 10:103350998-103350999 - TCGA-G2-A2ES-01 COSM1296893 c.141T>G p.P47P Substitution - coding silent 10:103350926-103350926 - S02384 COSM5698148 c.103A>C p.T35P Substitution - Missense 10:103350964-103350964 - Pat_04_A COSM5836176 c.671C>T p.P224L Substitution - Missense 10:103347240-103347240 - TCGA-AF-6136-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - 2296_T COSM3978051 c.640G>C p.E214Q Substitution - Missense 10:103326578-103326578 - CHC1545T COSM4787505 c.988G>A p.A330T Substitution - Missense 10:103314194-103314194 - S02348 COSM5691118 c.84delT p.V29fs*73 Deletion - Frameshift 10:103350983-103350983 - TCGA-F4-6808-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - LUAD-NYU1051S COSM368495 c.687A>G p.V229V Substitution - coding silent 10:103314270-103314270 - DLD1 COSM1675527 c.565C>T p.R189* Substitution - Nonsense 10:103347443-103347443 - S00050 COSM5657024 c.86T>C p.V29A Substitution - Missense 10:103350981-103350981 - TCGA-D5-7000-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - S02348 COSM5657024 c.86T>C p.V29A Substitution - Missense 10:103350981-103350981 - TCGA-D1-A101-01 COSM914320 c.273G>T p.E91D Substitution - Missense 10:103350794-103350794 - TCGA-14-0813-01 COSM2154707 c.553A>G p.I185V Substitution - Missense 10:103348720-103348720 - PT52 COSM5940063 c.997-8C>T p.? Unknown 10:103303969-103303969 - PTC-70C COSM5445985 c.69_70insCCGCCT p.P28_V29insPP Insertion - In frame 10:103350997-103350998 - PT09_2 COSM5894925 c.178C>T p.R60W Substitution - Missense 10:103350889-103350889 - T1204 COSM1675527 c.565C>T p.R189* Substitution - Nonsense 10:103347443-103347443 - 254 COSM3731481 c.666T>C p.P222P Substitution - coding silent 10:103347245-103347245 - S02342 COSM5692396 c.274G>A p.E92K Substitution - Missense 10:103350793-103350793 - ESCC_53 COSM5631241 c.414A>G p.K138K Substitution - coding silent 10:103348946-103348946 - TCGA-AA-3821-01 COSM294683 c.281A>C p.E94A Substitution - Missense 10:103350786-103350786 - KM12 COSM2059748 c.459C>T p.T153T Substitution - coding silent 10:103348901-103348901 - WSU-HN13 COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - LUAD-S01306 COSM343389 c.761C>T p.S254F Substitution - Missense 10:103345045-103345045 - TCGA-AH-6544-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - CHC1545T COSM4787506 c.763G>A p.A255T Substitution - Missense 10:103314194-103314194 - CLL146 COSM1289303 c.96C>A p.P32P Substitution - coding silent 10:103350971-103350971 - TCGA-BS-A0UA-01 COSM914323 c.261_263delAGA p.E89delE Deletion - In frame 10:103350804-103350806 - PT09_1 COSM5894925 c.178C>T p.R60W Substitution - Missense 10:103350889-103350889 - CCK81 COSM2059750 c.388C>G p.P130A Substitution - Missense 10:103348972-103348972 - TCGA-60-2698-01 COSM683493 c.597G>C p.K199N Substitution - Missense 10:103326621-103326621 - 432 COSM4433521 c.720delG p.Q240fs*5 Deletion - Frameshift 10:103314237-103314237 - LB1047-RCC COSM23379 c.877A>G p.R293G Substitution - Missense 10:103326566-103326566 - TCGA-F5-6702-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - NOKSI COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - TCGA-CI-6619-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - TCGA-CI-6619-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - WSU-HN6 COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - ESCC_53 COSM5631242 c.414A>G p.K138K Substitution - coding silent 10:103348946-103348946 - TCGA-G2-A2ES-01 COSM1296894 c.141T>G p.P47P Substitution - coding silent 10:103350926-103350926 - UPCI:SCC090 COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - TCGA-66-2785-01 COSM683490 c.4G>C p.E2Q Substitution - Missense 10:103351063-103351063 - ESO-177 COSM1261519 c.814T>C p.L272L Substitution - coding silent 10:103326629-103326629 - CLL146 COSM1289304 c.96C>A p.P32P Substitution - coding silent 10:103350971-103350971 - TCGA-CI-6620-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - NOKSI COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - UD-SCC-2 COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - HCT15 COSM1675527 c.565C>T p.R189* Substitution - Nonsense 10:103347443-103347443 - PT09_2 COSM5894926 c.178C>T p.R60W Substitution - Missense 10:103350889-103350889 - CHEWS004 COSM4573326 c.379G>A p.E127K Substitution - Missense 10:103348981-103348981 - TCGA-IR-A3LL-01 COSM4849890 c.574C>G p.Q192E Substitution - Missense 10:103347434-103347434 - TCGA-CM-5868-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - BHY COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - PT52 COSM5940064 c.772-8C>T p.? Unknown 10:103303969-103303969 - TCGA-14-0813 COSM2154706 c.553A>G p.I185V Substitution - Missense 10:103348720-103348720 - PT21_2 COSM5901671 c.656G>A p.R219K Substitution - Missense 10:103326562-103326562 - PTC-70C COSM5445986 c.69_70insCCGCCT p.P28_V29insPP Insertion - In frame 10:103350997-103350998 - BHY COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - TCGA-BP-5006-01 COSM465212 c.77C>A p.P26Q Substitution - Missense 10:103350990-103350990 - 8035591 COSM3382654 c.478G>A p.V160I Substitution - Missense 10:103348795-103348795 - KM12 COSM2059749 c.459C>T p.T153T Substitution - coding silent 10:103348901-103348901 - TCGA-AH-6544-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - LN229 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - C086 COSM5536743 c.635A>T p.H212L Substitution - Missense 10:103326583-103326583 - Gp2D COSM4626617 c.718C>T p.Q240* Substitution - Nonsense 10:103314239-103314239 - TCGA-DA-A1I7-06 COSM3433842 c.736C>T p.R246C Substitution - Missense 10:103345070-103345070 - PT32 COSM2059734 c.783-3C>T p.? Unknown 10:103333955-103333955 - SKNEP1 COSM2059737 c.674C>T p.A225V Substitution - Missense 10:103345132-103345132 - ORL-48 COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - Gp2D COSM4626616 c.943C>T p.Q315* Substitution - Nonsense 10:103314239-103314239 - TCGA-CM-5868-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - WSU-HN12 COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - TCGA-CI-6622-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - CAL27 COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - pfg019T COSM1638428 c.614-3delT p.? Unknown 10:103347300-103347300 - EOPC-01_tumor COSM3716374 c.721T>C p.Y241H Substitution - Missense 10:103314236-103314236 - KM12 COSM2059758 c.297_299delGGA p.E99delE Deletion - In frame 10:103350768-103350770 - S02322 COSM5691118 c.84delT p.V29fs*73 Deletion - Frameshift 10:103350983-103350983 - TCGA-F5-6702-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - KM12 COSM2059759 c.297_299delGGA p.E99delE Deletion - In frame 10:103350768-103350770 - TCGA-DY-A0XA-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - TCGA-CC-A7IL-01 COSM4912083 c.770T>C p.L257P Substitution - Missense 10:103345036-103345036 - CAL33 COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - HCT-15 COSM1675527 c.565C>T p.R189* Substitution - Nonsense 10:103347443-103347443 - PT32 COSM2059735 c.558-3C>T p.? Unknown 10:103333955-103333955 - TCGA-BS-A0UA-01 COSM914322 c.261_263delAGA p.E89delE Deletion - In frame 10:103350804-103350806 - TCGA-LL-A50Y-01 COSM5831383 c.68_69delTG p.L23fs*19 Deletion - Frameshift 10:103350998-103350999 - CHEWS004 COSM4573327 c.379G>A p.E127K Substitution - Missense 10:103348981-103348981 - TCGA-66-2785-01 COSM683491 c.4G>C p.E2Q Substitution - Missense 10:103351063-103351063 - S02322 COSM5691119 c.84delT p.V29fs*73 Deletion - Frameshift 10:103350983-103350983 - ORL-48 COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - UM-SCC-2 COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - S00050 COSM5657023 c.86T>C p.V29A Substitution - Missense 10:103350981-103350981 - N479T COSM236191 c.605T>C p.L202P Substitution - Missense 10:103347403-103347403 - UM-SCC-2 COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - CHC1545T COSM4787505 c.988G>A p.A330T Substitution - Missense 10:103314194-103314194 - T3152 COSM4712698 c.300C>A p.D100E Substitution - Missense 10:103350767-103350767 - LN229 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - T3152 COSM4712699 c.300C>A p.D100E Substitution - Missense 10:103350767-103350767 - TCGA-EW-A1OY-01 COSM1474326 c.742C>G p.R248G Substitution - Missense 10:103314215-103314215 - PCSI_0083_Pa_P_526 COSM3786313 c.684G>T p.Q228H Substitution - Missense 10:103326534-103326534 - EOPC-01_tumor COSM3716373 c.946T>C p.Y316H Substitution - Missense 10:103314236-103314236 - CSCC-20-T COSM4457526 c.824C>G p.T275S Substitution - Missense 10:103303909-103303909 - 2492715 COSM5657023 c.86T>C p.V29A Substitution - Missense 10:103350981-103350981 - TCGA-CD-8526-01 COSM4011355 c.381G>C p.E127D Substitution - Missense 10:103348979-103348979 - TCGA-EW-A1OY-01 COSM1474325 c.967C>G p.R323G Substitution - Missense 10:103314215-103314215 - C086 COSM5536742 c.860A>T p.H287L Substitution - Missense 10:103326583-103326583 - TCGA-AF-6136-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - UD-SCC-2 COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - CHC1545T COSM4787506 c.763G>A p.A255T Substitution - Missense 10:103314194-103314194 - T3090 COSM4712697 c.614-3_614-2insT p.? Unknown 10:103347299-103347300 - CSCC-10-T COSM343389 c.761C>T p.S254F Substitution - Missense 10:103345045-103345045 - 8035591 COSM3382655 c.478G>A p.V160I Substitution - Missense 10:103348795-103348795 - TCGA-F4-6808-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - LB1047-RCC COSM23505 c.652A>G p.R218G Substitution - Missense 10:103326566-103326566 - TCGA-14-0813 COSM2154707 c.553A>G p.I185V Substitution - Missense 10:103348720-103348720 - CAL33 COSM4603246 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - 2492715 COSM5657024 c.86T>C p.V29A Substitution - Missense 10:103350981-103350981 - TCGA-F4-6855-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - PCSI_0083_Pa_P_526 COSM3786312 c.909G>T p.Q303H Substitution - Missense 10:103326534-103326534 - TCGA-AA-3821-01 COSM294684 c.281A>C p.E94A Substitution - Missense 10:103350786-103350786 - S02384 COSM5698149 c.103A>C p.T35P Substitution - Missense 10:103350964-103350964 - TCGA-F5-6571-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - 432 COSM4433520 c.945delG p.Q315fs*5 Deletion - Frameshift 10:103314237-103314237 - ESO-177 COSM1261520 c.589T>C p.L197L Substitution - coding silent 10:103326629-103326629 - CSCC-20-T COSM4457525 c.1049C>G p.T350S Substitution - Missense 10:103303909-103303909 - TCGA-14-0813-01 COSM2154706 c.553A>G p.I185V Substitution - Missense 10:103348720-103348720 - TCGA-CI-6622-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - TCGA-F4-6855-01 COSM1560994 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - TCGA-DY-A0XA-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - TCGA-BM-6198-01 COSM3414650 c.715G>C p.E239Q Substitution - Missense 10:103314242-103314242 - CAL27 COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - TCGA-60-2698-01 COSM683492 c.822G>C p.K274N Substitution - Missense 10:103326621-103326621 - S02348 COSM5691119 c.84delT p.V29fs*73 Deletion - Frameshift 10:103350983-103350983 - TCGA-BP-5006-01 COSM465211 c.77C>A p.P26Q Substitution - Missense 10:103350990-103350990 - PT09_1 COSM5894926 c.178C>T p.R60W Substitution - Missense 10:103350889-103350889 - LUAD-S01306 COSM343390 c.639C>G p.F213L Substitution - Missense 10:103347272-103347272 - LUAD-5V8LT COSM401105 c.167G>T p.C56F Substitution - Missense 10:103350900-103350900 - TCGA-CI-6620-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - TCGA-AP-A0LM-01 COSM914318 c.361C>T p.R121C Substitution - Missense 10:103348999-103348999 - TCGA-AP-A0LM-01 COSM914319 c.361C>T p.R121C Substitution - Missense 10:103348999-103348999 - WSU-HN6 COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - TCGA-G4-6586-01 COSM5177983 c.782+6T>C p.? Unknown 10:103345018-103345018 - S02348 COSM5657023 c.86T>C p.V29A Substitution - Missense 10:103350981-103350981 - HCT8 COSM1675527 c.565C>T p.R189* Substitution - Nonsense 10:103347443-103347443 - TCGA-D1-A101-01 COSM914321 c.273G>T p.E91D Substitution - Missense 10:103350794-103350794 - TCGA-A7-A4SD-01 COSM2059759 c.297_299delGGA p.E99delE Deletion - In frame 10:103350768-103350770 - I2L-P19Ta-Tumor-Organoid COSM1504169 c.270G>A p.L90L Substitution - coding silent 10:103350797-103350797 - UPCI:SCC090 COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - PT21_2 COSM5901670 c.881G>A p.R294K Substitution - Missense 10:103326562-103326562 - TCGA-A7-A4SD-01 COSM2059758 c.297_299delGGA p.E99delE Deletion - In frame 10:103350768-103350770 - S02342 COSM5692395 c.274G>A p.E92K Substitution - Missense 10:103350793-103350793 - WSU-HN13 COSM4603245 c.84_85insGCCTCC p.P28_V29insAS Insertion - In frame 10:103350982-103350983 - LB1047-RCC COSM23379 c.877A>G p.R293G Substitution - Missense 10:103326566-103326566 - LUAD-NYU1051S COSM368494 c.912A>G p.V304V Substitution - coding silent 10:103314270-103314270 - TCGA-CD-8526-01 COSM4011356 c.381G>C p.E127D Substitution - Missense 10:103348979-103348979 - TCGA-F5-6571-01 COSM1560993 c.83_84insGCCTCC p.P28_V29insPP Insertion - In frame 10:103350983-103350984 - TCGA-BM-6198-01 COSM3414649 c.940G>C p.E314Q Substitution - Missense 10:103314242-103314242 - 2296_T COSM3978050 c.865G>C p.E289Q Substitution - Missense 10:103326578-103326578 - I2L-P19Ta-Tumor-Organoid COSM1504168 c.270G>A p.L90L Substitution - coding silent 10:103350797-103350797 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.741474 10q24.33 607816

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Synonymous p.P47P c.141T>G 10 105110683 BLCA A G IntronicSNV . c.557+584T>C 10 105107889 CLL A G Synonymous p.L272L c.814T>C 10 105086386 ESCA A - IntronicDeletion . c.614-3delT 10 105107057 STAD A - IntronicDeletion . c.810+18delT 10 105093664 STAD C A Missense p.R121L c.362G>T 10 105108755 LUAD G A Missense p.R246C c.736C>T 10 105104827 CM G C Missense p.R323G c.967C>G 10 105073972 BRCA G T Missense p.P26Q c.77C>A 10 105110747 RCCC G T Synonymous p.P32P c.96C>A 10 105110728 CLL T A 3-UTRSNV . c.1050+1063A>T 10 105062602 MB T C IntronicSNV . c.782+133A>G 10 105104648 HC T C Missense p.I185V c.553A>G 10 105108477 GBM TCT - InFrameDeletion p.E89delE c.261_263delAGA 10 105110561 UCEC