Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 16 88767738 88767738 + Missense_Mutation SNP C C A TCGA-ZF-A9RL-01A-11D-A38G-08 TCGA-ZF-A9RL-10A-01D-A38J-08 g.chr16:88767738C>A c.244G>T c.(244-246)Gac>Tac p.D82Y BLCA 16 88767739 88767739 + Silent SNP C C T TCGA-ZF-A9RL-01A-11D-A38G-08 TCGA-ZF-A9RL-10A-01D-A38J-08 g.chr16:88767739C>T c.243G>A c.(241-243)gtG>gtA p.V81V DLBC 16 88766062 88766062 + Missense_Mutation SNP C C T TCGA-FF-8062-01A-11D-2210-10 TCGA-FF-8062-10A-01D-2210-10 g.chr16:88766062C>T c.391G>A c.(391-393)Gtc>Atc p.V131I ESCA 16 88766056 88766056 + Missense_Mutation SNP C C T TCGA-LN-A4A5-01A-21D-A27G-09 TCGA-LN-A4A5-10A-01D-A27G-09 g.chr16:88766056C>T c.397G>A c.(397-399)Gtg>Atg p.V133M KIPAN 16 88765421 88765421 + Silent SNP C C A TCGA-BQ-5882-01A-11D-1589-08 TCGA-BQ-5882-11A-01D-1589-08 g.chr16:88765421C>A c.498G>T c.(496-498)gtG>gtT p.V166V KIRP 16 88765421 88765421 + Silent SNP C C A TCGA-BQ-5882-01A-11D-1589-08 TCGA-BQ-5882-11A-01D-1589-08 g.chr16:88765421C>A c.498G>T c.(496-498)gtG>gtT p.V166V LIHC 16 88764990 88764990 + Missense_Mutation SNP A A C TCGA-G3-A5SK-01A-11D-A27I-10 TCGA-G3-A5SK-10A-01D-A27I-10 g.chr16:88764990A>C c.568T>G c.(568-570)Tgg>Ggg p.W190G LIHC 16 88766049 88766049 + Missense_Mutation SNP G G T TCGA-BC-A112-01A-11D-A12Z-10 TCGA-BC-A112-11A-11D-A12Z-10 g.chr16:88766049G>T c.404C>A c.(403-405)cCc>cAc p.P135H LUAD 16 88767686 88767686 + Missense_Mutation SNP C C T TCGA-86-8056-01A-11D-2238-08 TCGA-86-8056-10A-01D-2238-08 g.chr16:88767686C>T c.296G>A c.(295-297)cGa>cAa p.R99Q LUAD 16 88767747 88767747 + Missense_Mutation SNP T T C TCGA-MP-A4T8-01A-11D-A24P-08 TCGA-MP-A4T8-10A-01D-A24P-08 g.chr16:88767747T>C c.235A>G c.(235-237)Aag>Gag p.K79E

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BRCA-EU 16 88758703 88758703 single base substitution A G downstream_gene_variant BRCA-EU 16 88758907 88758907 single base substitution G A downstream_gene_variant BRCA-EU 16 88759357 88759357 single base substitution T C downstream_gene_variant BRCA-EU 16 88759739 88759739 single base substitution C A downstream_gene_variant BRCA-EU 16 88760499 88760499 single base substitution C T downstream_gene_variant BRCA-EU 16 88760595 88760595 single base substitution C T downstream_gene_variant BRCA-EU 16 88761306 88761306 single base substitution C A downstream_gene_variant BRCA-EU 16 88762915 88762915 single base substitution G A 3_prime_UTR_variant BRCA-EU 16 88762915 88762915 single base substitution G A downstream_gene_variant BRCA-EU 16 88763686 88763686 single base substitution G A 3_prime_UTR_variant BRCA-EU 16 88763686 88763686 single base substitution G A downstream_gene_variant BRCA-EU 16 88763686 88763686 single base substitution G A intron_variant BRCA-EU 16 88765001 88765001 single base substitution G A downstream_gene_variant BRCA-EU 16 88765001 88765001 single base substitution G A intron_variant BRCA-EU 16 88765001 88765001 single base substitution G A missense_variant S105L 314C>T BRCA-EU 16 88765001 88765001 single base substitution G A missense_variant S186L 557C>T BRCA-EU 16 88765001 88765001 single base substitution G A missense_variant S77L 230C>T BRCA-EU 16 88765001 88765001 single base substitution G A upstream_gene_variant BRCA-EU 16 88767503 88767503 single base substitution C A downstream_gene_variant BRCA-EU 16 88767503 88767503 single base substitution C A intron_variant BRCA-EU 16 88767503 88767503 single base substitution C A upstream_gene_variant BRCA-EU 16 88770464 88770464 single base substitution G C intron_variant BRCA-EU 16 88770464 88770464 single base substitution G C upstream_gene_variant BRCA-EU 16 88771094 88771094 single base substitution C T intron_variant BRCA-EU 16 88771094 88771094 single base substitution C T upstream_gene_variant BRCA-EU 16 88771355 88771355 single base substitution G A intron_variant BRCA-EU 16 88771355 88771355 single base substitution G A upstream_gene_variant BRCA-EU 16 88772711 88772711 single base substitution A G missense_variant V8A 23T>C BRCA-EU 16 88772711 88772711 single base substitution A G upstream_gene_variant BRCA-EU 16 88772833 88772833 single base substitution G T upstream_gene_variant BRCA-EU 16 88776865 88776865 single base substitution G C upstream_gene_variant BRCA-FR 16 88759739 88759739 single base substitution C A downstream_gene_variant BRCA-FR 16 88761791 88761791 single base substitution C T downstream_gene_variant BRCA-FR 16 88772711 88772711 single base substitution A G missense_variant V8A 23T>C BRCA-FR 16 88772711 88772711 single base substitution A G upstream_gene_variant BRCA-US 16 88773618 88773618 single base substitution G T upstream_gene_variant BTCA-JP 16 88763902 88763902 single base substitution G A 3_prime_UTR_variant BTCA-JP 16 88763902 88763902 single base substitution G A downstream_gene_variant BTCA-JP 16 88763902 88763902 single base substitution G A exon_variant BTCA-JP 16 88763902 88763902 single base substitution G A intron_variant BTCA-JP 16 88763985 88763985 insertion of <=200bp - AG 3_prime_UTR_variant BTCA-JP 16 88763985 88763985 insertion of <=200bp - AG downstream_gene_variant BTCA-JP 16 88763985 88763985 insertion of <=200bp - AG exon_variant BTCA-JP 16 88763985 88763985 insertion of <=200bp - AG frameshift_variant S126S? BTCA-JP 16 88763985 88763985 insertion of <=200bp - AG frameshift_variant S154S? BTCA-JP 16 88763985 88763985 insertion of <=200bp - AG frameshift_variant S235S? BTCA-JP 16 88763985 88763985 insertion of <=200bp - AG intron_variant BTCA-JP 16 88765504 88765504 single base substitution G A downstream_gene_variant BTCA-JP 16 88765504 88765504 single base substitution G A intron_variant BTCA-JP 16 88765504 88765504 single base substitution G A upstream_gene_variant BTCA-JP 16 88773571 88773571 single base substitution G A upstream_gene_variant CLLE-ES 16 88773374 88773374 single base substitution T C upstream_gene_variant CLLE-ES 16 88776716 88776716 single base substitution C T upstream_gene_variant COCA-CN 16 88762944 88762944 single base substitution A T 3_prime_UTR_variant COCA-CN 16 88762944 88762944 single base substitution A T downstream_gene_variant COCA-CN 16 88773753 88773753 single base substitution C A upstream_gene_variant COCA-CN 16 88776192 88776192 single base substitution G A upstream_gene_variant EOPC-DE 16 88758518 88758518 single base substitution C T downstream_gene_variant EOPC-DE 16 88776920 88776920 single base substitution A C upstream_gene_variant EOPC-DE 16 88776942 88776942 single base substitution C T upstream_gene_variant ESAD-UK 16 88757986 88757986 single base substitution C T downstream_gene_variant ESAD-UK 16 88758296 88758296 single base substitution C T downstream_gene_variant ESAD-UK 16 88761672 88761672 single base substitution G C downstream_gene_variant ESAD-UK 16 88762942 88762942 single base substitution T A 3_prime_UTR_variant ESAD-UK 16 88762942 88762942 single base substitution T A downstream_gene_variant ESAD-UK 16 88764068 88764068 single base substitution G A 3_prime_UTR_variant ESAD-UK 16 88764068 88764068 single base substitution G A downstream_gene_variant ESAD-UK 16 88764068 88764068 single base substitution G A intron_variant ESAD-UK 16 88764861 88764861 single base substitution G A downstream_gene_variant ESAD-UK 16 88764861 88764861 single base substitution G A intron_variant ESAD-UK 16 88764861 88764861 single base substitution G A missense_variant L124F 370C>T ESAD-UK 16 88764861 88764861 single base substitution G A upstream_gene_variant ESAD-UK 16 88765108 88765108 single base substitution G A downstream_gene_variant ESAD-UK 16 88765108 88765108 single base substitution G A intron_variant ESAD-UK 16 88765108 88765108 single base substitution G A upstream_gene_variant ESAD-UK 16 88765326 88765326 single base substitution T C downstream_gene_variant ESAD-UK 16 88765326 88765326 single base substitution T C intron_variant ESAD-UK 16 88765326 88765326 single base substitution T C upstream_gene_variant ESAD-UK 16 88767228 88767228 single base substitution C T downstream_gene_variant ESAD-UK 16 88767228 88767228 single base substitution C T exon_variant ESAD-UK 16 88767228 88767228 single base substitution C T intron_variant ESAD-UK 16 88767228 88767228 single base substitution C T upstream_gene_variant ESAD-UK 16 88771267 88771267 single base substitution G A intron_variant ESAD-UK 16 88771267 88771267 single base substitution G A upstream_gene_variant ESAD-UK 16 88772581 88772581 single base substitution G A intron_variant ESAD-UK 16 88772581 88772581 single base substitution G A splice_region_variant ESAD-UK 16 88772581 88772581 single base substitution G A upstream_gene_variant ESAD-UK 16 88772872 88772872 single base substitution T C upstream_gene_variant ESAD-UK 16 88773704 88773732 deletion of <=200bp CTTTTTAAAAACATGTACTTACTTTATTC - upstream_gene_variant ESCA-CN 16 88765295 88765295 single base substitution C T downstream_gene_variant ESCA-CN 16 88765295 88765295 single base substitution C T intron_variant ESCA-CN 16 88765295 88765295 single base substitution C T upstream_gene_variant ESCA-CN 16 88772608 88772608 single base substitution C A intron_variant ESCA-CN 16 88772608 88772608 single base substitution C A synonymous_variant R21R 63G>T ESCA-CN 16 88772608 88772608 single base substitution C A synonymous_variant R42R 126G>T ESCA-CN 16 88772608 88772608 single base substitution C A upstream_gene_variant KIRP-US 16 88765421 88765421 single base substitution C A downstream_gene_variant KIRP-US 16 88765421 88765421 single base substitution C A intron_variant KIRP-US 16 88765421 88765421 single base substitution C A synonymous_variant V166V 498G>T KIRP-US 16 88765421 88765421 single base substitution C A synonymous_variant V57V 171G>T KIRP-US 16 88765421 88765421 single base substitution C A synonymous_variant V85V 255G>T KIRP-US 16 88765421 88765421 single base substitution C A upstream_gene_variant LAML-KR 16 88776920 88776920 single base substitution A C upstream_gene_variant LAML-KR 16 88776942 88776942 single base substitution C T upstream_gene_variant LICA-CN 16 88772608 88772608 single base substitution C A intron_variant LICA-CN 16 88772608 88772608 single base substitution C A synonymous_variant R21R 63G>T LICA-CN 16 88772608 88772608 single base substitution C A synonymous_variant R42R 126G>T LICA-CN 16 88772608 88772608 single base substitution C A upstream_gene_variant LIHC-US 16 88766049 88766049 single base substitution G T downstream_gene_variant LIHC-US 16 88766049 88766049 single base substitution G T missense_variant P114H 341C>A LIHC-US 16 88766049 88766049 single base substitution G T missense_variant P135H 404C>A LIHC-US 16 88766049 88766049 single base substitution G T missense_variant P22H 65C>A LIHC-US 16 88766049 88766049 single base substitution G T missense_variant P26H 77C>A LIHC-US 16 88766049 88766049 single base substitution G T missense_variant P54H 161C>A LIHC-US 16 88766049 88766049 single base substitution G T upstream_gene_variant LIHC-US 16 88776355 88776355 single base substitution C T upstream_gene_variant LIHC-US 16 88776364 88776364 single base substitution C G upstream_gene_variant LINC-JP 16 88772767 88772767 single base substitution T C 5_prime_UTR_variant LINC-JP 16 88772767 88772767 single base substitution T C upstream_gene_variant LINC-JP 16 88777766 88777766 single base substitution G A upstream_gene_variant LIRI-JP 16 88764819 88764819 single base substitution C A downstream_gene_variant LIRI-JP 16 88764819 88764819 single base substitution C A intron_variant LIRI-JP 16 88764819 88764819 single base substitution C A missense_variant V138F 412G>T LIRI-JP 16 88764819 88764819 single base substitution C A upstream_gene_variant LIRI-JP 16 88770249 88770249 single base substitution G A intron_variant LIRI-JP 16 88770249 88770249 single base substitution G A upstream_gene_variant LIRI-JP 16 88770904 88770904 single base substitution A G intron_variant LIRI-JP 16 88770904 88770904 single base substitution A G upstream_gene_variant LUSC-KR 16 88771329 88771329 single base substitution T C intron_variant LUSC-KR 16 88771329 88771329 single base substitution T C upstream_gene_variant LUSC-KR 16 88771552 88771552 single base substitution T C intron_variant LUSC-KR 16 88771552 88771552 single base substitution T C upstream_gene_variant MALY-DE 16 88765414 88765414 single base substitution A G downstream_gene_variant MALY-DE 16 88765414 88765414 single base substitution A G intron_variant MALY-DE 16 88765414 88765414 single base substitution A G missense_variant C169R 505T>C MALY-DE 16 88765414 88765414 single base substitution A G missense_variant C60R 178T>C MALY-DE 16 88765414 88765414 single base substitution A G missense_variant C88R 262T>C MALY-DE 16 88765414 88765414 single base substitution A G upstream_gene_variant MALY-DE 16 88768578 88768578 single base substitution C T intron_variant MALY-DE 16 88768578 88768578 single base substitution C T upstream_gene_variant MALY-DE 16 88776409 88776409 single base substitution C T upstream_gene_variant MELA-AU 16 88758024 88758024 single base substitution G A downstream_gene_variant MELA-AU 16 88758042 88758042 single base substitution G A downstream_gene_variant MELA-AU 16 88758194 88758194 single base substitution G A downstream_gene_variant MELA-AU 16 88758908 88758908 single base substitution G A downstream_gene_variant MELA-AU 16 88759062 88759062 single base substitution C T downstream_gene_variant MELA-AU 16 88759555 88759555 single base substitution C T downstream_gene_variant MELA-AU 16 88759566 88759566 single base substitution C T downstream_gene_variant MELA-AU 16 88759817 88759817 single base substitution G A downstream_gene_variant MELA-AU 16 88759849 88759849 single base substitution G A downstream_gene_variant MELA-AU 16 88759857 88759857 single base substitution G A downstream_gene_variant MELA-AU 16 88760201 88760201 single base substitution G A downstream_gene_variant MELA-AU 16 88760298 88760298 single base substitution C T downstream_gene_variant MELA-AU 16 88760462 88760462 single base substitution C A downstream_gene_variant MELA-AU 16 88760542 88760542 single base substitution C T downstream_gene_variant MELA-AU 16 88760579 88760579 single base substitution G A downstream_gene_variant MELA-AU 16 88760689 88760689 single base substitution C T downstream_gene_variant MELA-AU 16 88760849 88760850 multiple base substitution (>=2bp and <=200bp) CC TT downstream_gene_variant MELA-AU 16 88760911 88760911 single base substitution G A downstream_gene_variant MELA-AU 16 88761170 88761170 single base substitution T A downstream_gene_variant MELA-AU 16 88761233 88761233 single base substitution G A downstream_gene_variant MELA-AU 16 88761334 88761334 single base substitution G A downstream_gene_variant MELA-AU 16 88762704 88762704 single base substitution G A downstream_gene_variant MELA-AU 16 88762719 88762719 single base substitution C T downstream_gene_variant MELA-AU 16 88762730 88762730 single base substitution G A downstream_gene_variant MELA-AU 16 88762826 88762826 single base substitution G A downstream_gene_variant MELA-AU 16 88762828 88762828 single base substitution G A downstream_gene_variant MELA-AU 16 88762846 88762846 single base substitution A G downstream_gene_variant MELA-AU 16 88763661 88763661 single base substitution G A 3_prime_UTR_variant MELA-AU 16 88763661 88763661 single base substitution G A downstream_gene_variant MELA-AU 16 88763661 88763661 single base substitution G A intron_variant MELA-AU 16 88763812 88763812 single base substitution C T 3_prime_UTR_variant MELA-AU 16 88763812 88763812 single base substitution C T downstream_gene_variant MELA-AU 16 88763812 88763812 single base substitution C T exon_variant MELA-AU 16 88763812 88763812 single base substitution C T intron_variant MELA-AU 16 88764078 88764078 single base substitution G A 3_prime_UTR_variant MELA-AU 16 88764078 88764078 single base substitution G A downstream_gene_variant MELA-AU 16 88764078 88764078 single base substitution G A intron_variant MELA-AU 16 88764742 88764763 deletion of <=200bp ACCTGCAGGCAGCCCCCACAGA - downstream_gene_variant MELA-AU 16 88764742 88764763 deletion of <=200bp ACCTGCAGGCAGCCCCCACAGA - frameshift_variant VLWGLPAG156 MELA-AU 16 88764742 88764763 deletion of <=200bp ACCTGCAGGCAGCCCCCACAGA - intron_variant MELA-AU 16 88764742 88764763 deletion of <=200bp ACCTGCAGGCAGCCCCCACAGA - upstream_gene_variant MELA-AU 16 88764984 88764984 single base substitution C T downstream_gene_variant MELA-AU 16 88764984 88764984 single base substitution C T intron_variant MELA-AU 16 88764984 88764984 single base substitution C T missense_variant D111N 331G>A MELA-AU 16 88764984 88764984 single base substitution C T missense_variant D192N 574G>A MELA-AU 16 88764984 88764984 single base substitution C T missense_variant D83N 247G>A MELA-AU 16 88764984 88764984 single base substitution C T upstream_gene_variant MELA-AU 16 88765689 88765689 single base substitution C A downstream_gene_variant MELA-AU 16 88765689 88765689 single base substitution C A intron_variant MELA-AU 16 88765689 88765689 single base substitution C A upstream_gene_variant MELA-AU 16 88765978 88765978 single base substitution G A downstream_gene_variant MELA-AU 16 88765978 88765978 single base substitution G A intron_variant MELA-AU 16 88765978 88765978 single base substitution G A upstream_gene_variant MELA-AU 16 88766057 88766057 single base substitution G A downstream_gene_variant MELA-AU 16 88766057 88766057 single base substitution G A synonymous_variant P111P 333C>T MELA-AU 16 88766057 88766057 single base substitution G A synonymous_variant P132P 396C>T MELA-AU 16 88766057 88766057 single base substitution G A synonymous_variant P19P 57C>T MELA-AU 16 88766057 88766057 single base substitution G A synonymous_variant P23P 69C>T MELA-AU 16 88766057 88766057 single base substitution G A synonymous_variant P51P 153C>T MELA-AU 16 88766057 88766057 single base substitution G A upstream_gene_variant MELA-AU 16 88768458 88768458 single base substitution G A intron_variant MELA-AU 16 88768458 88768458 single base substitution G A upstream_gene_variant MELA-AU 16 88768472 88768472 single base substitution G A intron_variant MELA-AU 16 88768472 88768472 single base substitution G A upstream_gene_variant MELA-AU 16 88768958 88768958 single base substitution G A intron_variant MELA-AU 16 88768958 88768958 single base substitution G A upstream_gene_variant MELA-AU 16 88769843 88769843 single base substitution G A 5_prime_UTR_variant MELA-AU 16 88769843 88769843 single base substitution G A exon_variant MELA-AU 16 88769843 88769843 single base substitution G A intron_variant MELA-AU 16 88769843 88769843 single base substitution G A upstream_gene_variant MELA-AU 16 88770337 88770337 single base substitution C T intron_variant MELA-AU 16 88770337 88770337 single base substitution C T upstream_gene_variant MELA-AU 16 88770835 88770836 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 16 88770835 88770836 multiple base substitution (>=2bp and <=200bp) GG AA upstream_gene_variant MELA-AU 16 88771775 88771775 single base substitution C T intron_variant MELA-AU 16 88771775 88771775 single base substitution C T upstream_gene_variant MELA-AU 16 88772830 88772830 single base substitution G A upstream_gene_variant MELA-AU 16 88772873 88772873 single base substitution C T upstream_gene_variant MELA-AU 16 88772886 88772886 single base substitution G A upstream_gene_variant MELA-AU 16 88773381 88773381 single base substitution C T upstream_gene_variant MELA-AU 16 88774592 88774592 single base substitution C T upstream_gene_variant MELA-AU 16 88776191 88776191 single base substitution C T upstream_gene_variant MELA-AU 16 88776781 88776781 single base substitution G A upstream_gene_variant OV-AU 16 88768574 88768574 single base substitution C G intron_variant OV-AU 16 88768574 88768574 single base substitution C G upstream_gene_variant PACA-AU 16 88771415 88771415 single base substitution G A intron_variant PACA-AU 16 88771415 88771415 single base substitution G A upstream_gene_variant PACA-CA 16 88759507 88759507 single base substitution G T downstream_gene_variant PACA-CA 16 88760656 88760656 single base substitution C T downstream_gene_variant PACA-CA 16 88763636 88763636 single base substitution C T 3_prime_UTR_variant PACA-CA 16 88763636 88763636 single base substitution C T downstream_gene_variant PACA-CA 16 88763636 88763636 single base substitution C T intron_variant PACA-CA 16 88763921 88763921 single base substitution C T 3_prime_UTR_variant PACA-CA 16 88763921 88763921 single base substitution C T downstream_gene_variant PACA-CA 16 88763921 88763921 single base substitution C T exon_variant PACA-CA 16 88763921 88763921 single base substitution C T intron_variant PACA-CA 16 88764121 88764121 single base substitution C T 3_prime_UTR_variant PACA-CA 16 88764121 88764121 single base substitution C T downstream_gene_variant PACA-CA 16 88764121 88764121 single base substitution C T intron_variant PACA-CA 16 88768366 88768366 single base substitution C T intron_variant PACA-CA 16 88768366 88768366 single base substitution C T upstream_gene_variant PACA-CA 16 88769461 88769461 single base substitution C A 5_prime_UTR_variant PACA-CA 16 88769461 88769461 single base substitution C A exon_variant PACA-CA 16 88769461 88769461 single base substitution C A intron_variant PACA-CA 16 88769461 88769461 single base substitution C A upstream_gene_variant PACA-CA 16 88772085 88772085 single base substitution C T intron_variant PACA-CA 16 88772085 88772085 single base substitution C T upstream_gene_variant PACA-CA 16 88774934 88774934 single base substitution T C upstream_gene_variant PBCA-DE 16 88768567 88768567 single base substitution C T intron_variant PBCA-DE 16 88768567 88768567 single base substitution C T upstream_gene_variant PBCA-DE 16 88769104 88769104 single base substitution C T intron_variant PBCA-DE 16 88769104 88769104 single base substitution C T upstream_gene_variant PRAD-CA 16 88763958 88763958 single base substitution G A 3_prime_UTR_variant PRAD-CA 16 88763958 88763958 single base substitution G A downstream_gene_variant PRAD-CA 16 88763958 88763958 single base substitution G A exon_variant PRAD-CA 16 88763958 88763958 single base substitution G A intron_variant PRAD-CA 16 88773903 88773903 single base substitution C A upstream_gene_variant PRAD-UK 16 88758938 88758938 single base substitution C T downstream_gene_variant RECA-EU 16 88762520 88762520 single base substitution C G downstream_gene_variant SKCA-BR 16 88758012 88758012 single base substitution T G downstream_gene_variant SKCA-BR 16 88758492 88758492 single base substitution T C downstream_gene_variant SKCA-BR 16 88759110 88759110 single base substitution T C downstream_gene_variant SKCA-BR 16 88759551 88759551 single base substitution C T downstream_gene_variant SKCA-BR 16 88759948 88759948 single base substitution T C downstream_gene_variant SKCA-BR 16 88759949 88759949 single base substitution C T downstream_gene_variant SKCA-BR 16 88761335 88761335 single base substitution G A downstream_gene_variant SKCA-BR 16 88761503 88761503 single base substitution C A downstream_gene_variant SKCA-BR 16 88764630 88764630 single base substitution C T 3_prime_UTR_variant SKCA-BR 16 88764630 88764630 single base substitution C T downstream_gene_variant SKCA-BR 16 88764630 88764630 single base substitution C T intron_variant SKCA-BR 16 88764630 88764630 single base substitution C T upstream_gene_variant SKCA-BR 16 88764926 88764926 single base substitution G A downstream_gene_variant SKCA-BR 16 88764926 88764926 single base substitution G A intron_variant SKCA-BR 16 88764926 88764926 single base substitution G A missense_variant S102F 305C>T SKCA-BR 16 88764926 88764926 single base substitution G A missense_variant S130F 389C>T SKCA-BR 16 88764926 88764926 single base substitution G A missense_variant S211F 632C>T SKCA-BR 16 88764926 88764926 single base substitution G A upstream_gene_variant SKCA-BR 16 88765067 88765067 single base substitution T G downstream_gene_variant SKCA-BR 16 88765067 88765067 single base substitution T G intron_variant SKCA-BR 16 88765067 88765067 single base substitution T G upstream_gene_variant SKCA-BR 16 88765509 88765509 single base substitution T G downstream_gene_variant SKCA-BR 16 88765509 88765509 single base substitution T G intron_variant SKCA-BR 16 88765509 88765509 single base substitution T G upstream_gene_variant SKCA-BR 16 88773544 88773544 single base substitution C T upstream_gene_variant SKCA-BR 16 88774068 88774068 single base substitution A C upstream_gene_variant SKCA-BR 16 88774208 88774208 single base substitution G T upstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand 587228 COSM1223930 c.535C>T p.R179C Substitution - Missense 16:88698976-88698976 - PD6733b COSM5795899 c.557C>T p.S186L Substitution - Missense 16:88698593-88698593 - TCGA-BC-A112-01 COSM4936502 c.404C>A p.P135H Substitution - Missense 16:88699641-88699641 - I2L-P7-Tumor-Organoid COSM5363742 c.636C>T p.Y212Y Substitution - coding silent 16:88698514-88698514 - BD124T COSM5493483 c.704_705insCT p.E236fs*>3 Insertion - Frameshift 16:88697577-88697578 - Gp5D COSM2922308 c.200C>T p.P67L Substitution - Missense 16:88701374-88701374 - T3724 COSM4722027 c.156-1G>T p.? Unknown 16:88701419-88701419 - 041T COSM1729112 c.413A>T p.Q138L Substitution - Missense 16:88699632-88699632 - TCGA-D1-A17U-01 COSM974738 c.218G>T p.R73L Substitution - Missense 16:88701356-88701356 - SJRHB059R COSM3737115 c.506_507delGT p.V170fs*51 Deletion - Frameshift 16:88699004-88699005 - LP2000108-DNA_A01 COSM4408402 c.153C>T p.H51H Substitution - coding silent 16:88706173-88706173 - ESCC_BICR_045T COSM5441612 c.126G>T p.R42R Substitution - coding silent 16:88706200-88706200 - TCGA-BQ-5882-01 COSM3988717 c.498G>T p.V166V Substitution - coding silent 16:88699013-88699013 - GC_342T_a-GC_342N COSM4771922 c.558G>T p.S186S Substitution - coding silent 16:88698592-88698592 - Gp2D COSM2922308 c.200C>T p.P67L Substitution - Missense 16:88701374-88701374 - ICC013T COSM5441612 c.126G>T p.R42R Substitution - coding silent 16:88706200-88706200 - PTC-7C COSM4129485 c.213C>G p.L71L Substitution - coding silent 16:88701361-88701361 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.513804 16q24.3

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer G A Synonymous p.I144I c.432C>T 16 88765487 CM