PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus KLHL10 SUGT1 25036637 intact exp G G G G G G G G G G G G HSP90AB1 KLHL10 22939624 intact exp G G G G G G G G G G G G KLHL10 KLHL10 17047026 intact exp G G G G G G G G G G G G HSP90AA1 KLHL10 22939624 biogrid exp G G G G G G G G G G G G KLHL10 NUDCD3 25036637 intact exp G G G G G G G G G G G G CUL3 KLHL10 ortho G G G G G G G G G G G G KLHL10 BIRC6 ortho G G G G G G G G G G G G KLHL10 PIWIL1 25402006 ortho, pred G G HOXA13 KLHL10 23023127 pred G KLHL10 STRBP 23023127 pred G G G G G G G G G G G G BCL6 KLHL10 23023127 pred G G G G G G G G G G G G SOCS3 KLHL10 23023127 pred G G G G G G G G G G G G AXIN1 KLHL10 23023127 pred G G G G G G G G G G G KLHL10 GOPC 23023127 pred G G G G G G G G G G G G ZBTB16 KLHL10 23023127 pred G G G G G G G G G G G G HOXD13 KLHL10 23023127 pred LAMC1 KLHL10 23023127 pred G G G G G G G G G G G G SHH KLHL10 23023127 pred G G G G G G G G G ROR2 KLHL10 23023127 pred G G VHL KLHL10 23023127 pred G G G G G G G G G G G CD46 KLHL10 23023127 pred G G G G G G G G G G G G KLHL10 ADAD1 23023127 pred G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q6JEL2 P07900-2 affinity chromatography technology 22939624 physical association X 2 Q8IVD9 Q6JEL2 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q6JEL2 Q6JEL2 two hybrid 17047026 physical association X 2 Q6JEL2 Q6JEL2 two hybrid 17047026 physical association X 2 Q6JEL2 Q9JLV5 two hybrid 17047026 physical association X 2 Q6JEL2 A0A024RD80 luminescence based mammalian interactome mapping 22939624 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality B4DYC6 KLHL10 25036637 0729 HT HSP90AB1 KLHL10 22939624 0729 HT KLHL10 KLHL10 17047026 0018 LC KLHL10 NUDCD3 25036637 0729 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q6JEL2 P07900 KLHL10 HSP90AA1 0.126 22939624 Q8IVD9 Q6JEL2 NUDCD3 KLHL10 0.126 25036637 Q6JEL2 P08238 KLHL10 HSP90AB1 0.126 22939624 Q6JEL2 B4DYC6 KLHL10 B4DYC6 0.126 25036637 Q9H4Y5 Q6JEL2 GSTO2 KLHL10 0.236 unassigned1304

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 HSP90AA1 KLHL10 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AB1 KLHL10 MI:0045 experimental interaction detection MI:0461 interaction database CUL3 KLHL10 MI:0362 inference MI:0461 interaction database KLHL10 NUDCD3 MI:0045 experimental interaction detection MI:0461 interaction database