PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TRAPPC2B JOSD2 26186194,19615732 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HBB JOSD2 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 AHCYL2 26186194,19615732 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TYSND1 JOSD2 26186194,19615732 biogrid,intact exp G G G G G G G G G G G G G G DUSP28 JOSD2 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBC JOSD2 21118805,23625928 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMARCA2 JOSD2 19615732 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLA2G2A JOSD2 22118674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 SPRR3 26186194 biogrid exp G G G G G G G G G MCEMP1 JOSD2 26186194 biogrid exp G G G G TRAPPC2 JOSD2 19615732 intact exp AHCYL1 JOSD2 26186194,19615732 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 STUB1 23625928 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN11 JOSD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBC JOSD2 23023127 pred FRMD7 JOSD2 23023127 pred ARAF JOSD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 UBTD1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 FAF1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 UBLCP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 ASPSCR1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G RAD23A JOSD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HERPUD1 JOSD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBQLNL JOSD2 23023127 pred G G RGS14 JOSD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 UBXN10 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 TMUB1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 UBL5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 JOSD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JOSD2 UBQLN1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B JOSD2 AHCYL2 MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_120318 bait prey PLA2G2A JOSD2 MI:0415(enzymatic study) 22118674 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_160294 prey bait TRAPPC2P1 JOSD2 MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_119786 prey bait SMARCA2 JOSD2 MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_119800 prey bait JOSD2 STUB1 MI:0415(enzymatic study) 23625928 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_309271 prey bait TYSND1 JOSD2 MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_120851 prey bait UBC JOSD2 MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 21890473,21906983,23625928 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_177865|BIOGRID_309267|BIOGRID_173676 bait|prey|bait prey|bait|prey AHCYL1 JOSD2 MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_120197 prey bait

PPI - HINT Gene A Gene B PMID Method Quality AHCYL1 JOSD2 26186194,19615732,19615732 0004,0004,0007 HT TRAPPC2 JOSD2 19615732 0004 HT TRAPPC2B JOSD2 19615732 0007 HT SMARCA2 JOSD2 19615732,19615732 0004,0007 HT HBB JOSD2 26186194 0004 HT TYSND1 JOSD2 26186194,19615732,19615732 0004,0004,0007 HT DUSP28 JOSD2 26186194 0004 HT ZNF547 JOSD2 19615732,26186194 0004,0004 HT MCEMP1 JOSD2 26186194 0004 HT Q8N9Q1 JOSD2 19615732 0004 HT JOSD2 AHCYL2 26186194,19615732,19615732 0004,0004,0007 HT JOSD2 SPRR3 26186194 0004 HT AHCYL1 JOSD2 26186194,19615732,19615732 0004,0004,0007 HT TRAPPC2 JOSD2 19615732 0004 HT TRAPPC2B JOSD2 19615732 0007 HT SMARCA2 JOSD2 19615732,19615732 0004,0007 HT HBB JOSD2 26186194 0004 HT TYSND1 JOSD2 26186194,19615732,19615732 0004,0004,0007 HT DUSP28 JOSD2 26186194 0004 HT ZNF547 JOSD2 19615732,26186194 0004,0004 HT MCEMP1 JOSD2 26186194 0004 HT Q8N9Q1 JOSD2 19615732 0004 HT JOSD2 AHCYL2 26186194,19615732,19615732 0004,0004,0007 HT JOSD2 SPRR3 26186194 0004 HT UBC JOSD2 21118805,23625928 0415,0415 LC PLA2G2A JOSD2 22118674 0415 LC JOSD2 STUB1 23625928 0415 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8TAC2 Q8IX19 JOSD2 MCEMP1 0.126 26186194 Q8TAC2 P14555 JOSD2 PLA2G2A 0.309 22118674 Q8TAC2 P51531 JOSD2 SMARCA2 0.126 19615732 Q8TAC2 P68871 JOSD2 HBB 0.126 26186194 Q8TAC2 Q4G0W2 JOSD2 DUSP28 0.126 26186194 Q8TAC2 O43865 JOSD2 AHCYL1 0.236 19615732,26186194 Q8TAC2 P0DI82 JOSD2 TRAPPC2P1 0.236 19615732,26186194 Q8TAC2 P0CG48 JOSD2 UBC 0.523 23625928,21118805 Q8TAC2 Q2T9J0 JOSD2 TYSND1 0.236 19615732,26186194 Q96HN2 Q8TAC2 AHCYL2 JOSD2 0.236 19615732,26186194 Q96DZ9 Q8TAC2 CMTM5 JOSD2 0.236 unassigned1304 Q8TAC2 O95070 JOSD2 YIF1A 0.236 unassigned1304 Q8TAC2 P0DI81 JOSD2 TRAPPC2 0.416 26186194,unassigned1304,19615732 Q9UBC9 Q8TAC2 SPRR3 JOSD2 0.126 26186194 Q9UNE7 Q8TAC2 STUB1 JOSD2 0.309 23625928

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 AHCYL1 JOSD2 MI:0045 experimental interaction detection MI:0461 interaction database UBB JOSD2 MI:0362 inference MI:1106 pathways database UBC JOSD2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TRAPPC2 JOSD2 MI:0045 experimental interaction detection MI:0461 interaction database TRAPPC2B JOSD2 MI:0045 experimental interaction detection MI:0461 interaction database PLA2G2A JOSD2 MI:0045 experimental interaction detection MI:0461 interaction database SMARCA2 JOSD2 MI:0045 experimental interaction detection MI:0461 interaction database RPS27A JOSD2 MI:0362 inference MI:1106 pathways database UBA52 JOSD2 MI:0362 inference MI:1106 pathways database HBB JOSD2 MI:0045 experimental interaction detection MI:0461 interaction database TYSND1 JOSD2 MI:0045 experimental interaction detection MI:0461 interaction database DUSP28 JOSD2 MI:0045 experimental interaction detection MI:0461 interaction database MCEMP1 JOSD2 MI:0045 experimental interaction detection MI:0461 interaction database JOSD2 AHCYL2 MI:0045 experimental interaction detection MI:0461 interaction database JOSD2 SPRR3 MI:0045 experimental interaction detection MI:0461 interaction database JOSD2 STUB1 MI:0045 experimental interaction detection MI:0461 interaction database