PTM - CPLM Gene Name UniProt ID Type Position Code UBXN1; SAKS1 Q04323 Ubiquitination 83 K UBXN1; SAKS1 Q04323 Ubiquitination 105 K UBXN1; SAKS1 Q04323 Ubiquitination 154 K UBXN1; SAKS1 Q04323 Ubiquitination 178 K UBXN1; SAKS1 Q04323 Ubiquitination 294 K UBXN1; SAKS1 Q04323 Ubiquitination 208 K UBXN1; SAKS1 Q04323 Ubiquitination 96 K UBXN1; SAKS1 Q04323 Ubiquitination 293 K

PTM - dbPAF Gene Name UniProt ID Position Type Species UBXN1; SAKS1 Q04323 132 S Homo sapiens(Human) UBXN1; SAKS1 Q04323 179 Y Homo sapiens(Human) UBXN1; SAKS1 Q04323 199 S Homo sapiens(Human) UBXN1; SAKS1 Q04323 200 S Homo sapiens(Human) UBXN1; SAKS1 Q04323 202 S Homo sapiens(Human) UBXN1; SAKS1 Q04323 207 T Homo sapiens(Human) UBXN1; SAKS1 Q04323 229 T Homo sapiens(Human) UBXN1; SAKS1 Q04323 242 Y Homo sapiens(Human) UBXN1; SAKS1 Q04323 262 S Homo sapiens(Human) UBXN1; SAKS1 Q04323 270 S Homo sapiens(Human) UBXN1; SAKS1 Q04323 297 S Homo sapiens(Human) UBXN1; SAKS1 Q04323 75 S Homo sapiens(Human) UBXN1; SAKS1 Q04323 87 S Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type UBXN1; SAKS1 rs1050329 TCT->TTT S->F 200 S EPGPVPSSPSQEPPT 200 Phosphorylation TypeI- UBXN1; SAKS1 rs1050329 TCT->TTT S->F 199 S PEPGPVPSSPSQEPP 199 Phosphorylation TypeII- UBXN1; SAKS1 rs1050329 TCT->TTT S->F 207 T SPSQEPPTKREYDQC 207 Phosphorylation TypeII- UBXN1; SAKS1 rs1050329 TCT->TTT S->F 202 S GPVPSSPSQEPPTKR 202 Phosphorylation TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q04323 S87-p Phosphorylation GEGkPALsEEERQEQ Q04323 S132-p Phosphorylation RRQGQELsAARQRLQ Q04323 Y179-p Phosphorylation KAERAKkyGGSVGSQ Q04323 S199-p Phosphorylation PEPGPVPssPsQEPP Q04323 S200-p Phosphorylation EPGPVPssPsQEPPt Q04323 S202-p Phosphorylation GPVPssPsQEPPtkR Q04323 T207-p Phosphorylation sPsQEPPtkREYDQC Q04323 T229-p Phosphorylation DGTSLTQtFRAREQL Q04323 Y242-p Phosphorylation QLAAVRLyVELHRGE Q04323 S262-p Phosphorylation QDPVQLLsGFPRRAF Q04323 S270-p Phosphorylation GFPRRAFsEADMERP Q04323 K83-ub Ubiquitination GSAAGEGkPALsEEE Q04323 K96-ub Ubiquitination EERQEQTkRMLELVA Q04323 K105-ub Ubiquitination MLELVAQkQREREER Q04323 K154-ub Ubiquitination AEERRREkAEELAAR Q04323 K178-ub Ubiquitination DKAERAKkyGGSVGS Q04323 K208-ub Ubiquitination PsQEPPtkREYDQCR Q04323 K293-ub Ubiquitination SAVLIVAkkCPS___ Q04323 K294-ub Ubiquitination AVLIVAkkCPS____

PTM - dbPTM UniProt ID Position Code Type Resources References Q04323 179 Y Phosphorylation Swiss-Prot 1010711 17287340 Q04323 199 S Phosphorylation Swiss-Prot 1010711 17287340;18669648 Q04323 200 S Phosphorylation Swiss-Prot 1010711 15362974;17287340 Q04323 207 T Phosphorylation Swiss-Prot 1010711 17287340 Q04323 270 S Phosphorylation Swiss-Prot 1010711 19690332 Q04323 199 S Phosphorylation PhosphoELM.10011 18669648 Q04323 200 S Phosphorylation PhosphoELM.10011 18669648;15362974 Q04323 202 S Phosphorylation PhosphoELM.10011 18669648 Q04323 207 T Phosphorylation PhosphoELM.10011 18669648 Q04323 105 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q04323 154 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q04323 178 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q04323 208 K Ubiquitylation Phosphositeplus.1010730 21906983 Q04323 293 K Ubiquitylation Phosphositeplus.1010730 21906983 Q04323 83 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q04323 96 K Ubiquitylation Phosphositeplus.1010730 21906983 Q04323 199 S Phosphorylation Phosphositeplus.1010730 17287340;18669648;18847512 Q04323 200 S Phosphorylation Phosphositeplus.1010730 15362974;17287340;18847512 Q04323 202 S Phosphorylation Phosphositeplus.1010730 18077418;18669648;18847512 Q04323 270 S Phosphorylation Phosphositeplus.1010730 19690332 Q04323 207 T Phosphorylation Phosphositeplus.1010730 17287340 Q04323 179 Y Phosphorylation Phosphositeplus.1010730 17287340 Q04323 199 S Phosphorylation HPRD 9.0 18669648,17287340,19413330 Q04323 200 S Phosphorylation HPRD 9.0 18669648,17287340,19413330,20068231 Q04323 202 S Phosphorylation HPRD 9.0 18669648,18077418,19413330 Q04323 207 T Phosphorylation HPRD 9.0 18669648,17287340 Q04323 229 T Phosphorylation HPRD 9.0 18212344 Q04323 179 Y Phosphorylation HPRD 9.0 17287340 Q04323 199 S Phosphorylation SysPTM 1.1 18669648;17287340 Q04323 200 S Phosphorylation SysPTM 1.1 17287340 Q04323 207 T Phosphorylation SysPTM 1.1 17287340 Q04323 229 T Phosphorylation SysPTM 1.1 18212344 Q04323 179 Y Phosphorylation SysPTM 1.1 17287340

PTM - HPRD Symbol Position Code Type References UBXN1 179 Y Phosphorylation 17287340 UBXN1 199 S Phosphorylation 18669648,17287340,19413330 UBXN1 200 S Phosphorylation 18669648,17287340,19413330,20068231 UBXN1 202 S Phosphorylation 18669648,18077418,19413330 UBXN1 207 T Phosphorylation 18669648,17287340 UBXN1 229 T Phosphorylation 18212344

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q04323 207 T 18669648 HTP Phosphorylation Q04323 202 S 18669648 HTP Phosphorylation Q04323 200 S 18669648 HTP Phosphorylation Q04323 200 S 15362974 LTP Phosphorylation Q04323 199 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q04323 2 N-acetylalanine 19413330;25944712 Q04323 199 Phosphoserine 18669648 Q04323 200 Phosphoserine; by MAPK12 15362974 Q04323 207 Phosphothreonine 24275569 Q04323 229 Phosphothreonine 23186163 Q04323 270 Phosphoserine 19690332;24275569

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 51035 119239 - K Ubiquitination 18781797 51035 119239 - K Ubiquitination 21987572 51035 119239 - K Ubiquitination 21139048 51035 119239 - K Ubiquitination 21890473 51035 119239 - K Ubiquitination 21906983 51035 119239 - K Ubiquitination 16396636 51035 119239 - K Ubiquitination 22053931 51035 119239 - K Ubiquitination 22505724 51035 119239 - K Ubiquitination 21963094 51035 119239 - K Ubiquitination 23000965 51035 119239 - K Ubiquitination 24654937 51035 119239 - K Ubiquitination 24816145 51035 119239 - K Ubiquitination 25015289 51035 119239 - K Ubiquitination 25147182 51035 119239 - K Neddylation 18247557

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID UBXN1 Homo sapiens (Human) 154; 83; 178; 105 "154,EERRREKAEELAA; 83,SAAGEGKPALSEE; 178,KAERAKKYGGSVG; 105,LELVAQKQREREE" 154:21890473; 83:21890473; 178:21890473; 105:21890473 UBXN1 Homo sapiens (Human) 154; 83; 178; 105 "154,EERRREKAEELAA; 83,SAAGEGKPALSEE; 178,KAERAKKYGGSVG; 105,LELVAQKQREREE" 154:21890473; 83:21890473; 178:21890473; 105:21890473 UBXN1 Homo sapiens (Human) 154; 83; 105 "154,EERRREKAEELAA; 83,SAAGEGKPALSEE; 105,LELVAQKQREREE" "154:22053931; 83:21139048,22053931; 105:21139048,22053931" UBXN1 Homo sapiens (Human) 154; 83; 96; 178; 208; 105 "154,EERRREKAEELAA; 83,SAAGEGKPALSEE; 96,ERQEQTKRMLELV; 178,KAERAKKYGGSVG; 208,SQEPPTKREYDQC; 105,LELVAQKQREREE" "154:21890473,21906983; 83:21890473,21906983; 96:21906983; 178:21890473,21906983; 208:21906983; 105:21890473,21906983" UBXN1 Homo sapiens (Human) 154; 293; 83; 96; 178; 208; 105 "154,EERRREKAEELAA; 293,AVLIVAKKCPS; 83,SAAGEGKPALSEE; 96,ERQEQTKRMLELV; 178,KAERAKKYGGSVG; 208,SQEPPTKREYDQC; 105,LELVAQKQREREE" "154:21890473,21906983; 293:21906983; 83:21890473,21906983; 96:21906983; 178:21890473,21906983; 208:21906983; 105:21890473,21906983" UBXN1 Homo sapiens (Human) 154; 83; 178; 105 "154,EERRREKAEELAA; 83,SAAGEGKPALSEE; 178,KAERAKKYGGSVG; 105,LELVAQKQREREE" 154:21890473; 83:21890473; 178:21890473; 105:21890473