Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 31206806 rs3795437 T C rs3795437 8.09E-05 Longevity HPOID:0000118 NA G intron GWASdb_trait 1 31206957 rs12404920 T C rs12404920 7.88E-05 Longevity HPOID:0000118 NA T intron GWASdb_trait 1 31207781 rs10914189 C T rs10914189 6.26E-04 Smoking initiation HPOID:0000707 DOID:0050742 C intron GWASdb_trait 1 31223657 rs1188349 G A rs1188349 5.00E-04 Acute lymphoblastic leukemia (childhood) HPOID:0006721 DOID:9952|DOID:12603 C intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs3790503 1 31229075 31229075 intronic 0.675255 0.17053219134729403 GWAS of prostate cancer rs1188360 1 31212376 31212376 intronic 0.343905 0.463561509968553 GWAS of prostate cancer rs11585511 1 31216969 31216969 intronic 0.320588 0.494052737849992 GWAS of prostate cancer rs1188352 1 31219289 31219289 intronic 0.231335 0.635758655353298

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000162511.7 LAPTM5 601476