Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 85529628 rs6576745 T C rs6576745 1.85E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_drug 1 85531711 rs6695223 C T rs6695223 3.32E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_drug 1 85531711 rs6695223 C T rs6695223 5.00E-09 FACTOR VIII TRANSCRIPTION FACTORS|HOMEODOMAIN PROTEINS|IRX3 PROTEIN, HUMAN Venous thromboembolism (gene x gene interaction) HPOID:0002204|HPOID:0002625 DOID:866|DOID:9477 C intron GWASdb_drug 1 85560264 rs709764 G A rs709764 3.79E-05 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_drug 1 85529628 rs6576745 T C rs6576745 1.85E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_trait 1 85531711 rs6695223 C T rs6695223 3.32E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_trait 1 85531711 rs6695223 C T rs6695223 5.00E-09 Venous thromboembolism (gene x gene interaction) HPOID:0002204|HPOID:0002625 DOID:866|DOID:9477 C intron GWASdb_trait 1 85537706 rs17099213 T C rs17099213 1.70E-05 Urinary metabolites HPOID:0000079 DOID:557 T intron GWASdb_trait 1 85539127 rs17120570 G A rs17120570 2.88E-04 Smoking initiation HPOID:0000707 DOID:0050742 G intron GWASdb_trait 1 85560264 rs709764 G A rs709764 3.79E-05 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_trait 1 85582549 rs2050842 G A rs2050842 4.60E-05 Diabetic retinopathy HPOID:0000819|HPOID:0000488 DOID:8947 A intron GWASdb_trait 1 85583162 rs6576749 C G rs6576749 4.60E-05 Diabetic retinopathy HPOID:0000819|HPOID:0000488 DOID:8947 G intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs817476 1 85596749 85596749 intronic 0.98252 0.00765860044237463 GWAS of prostate cancer rs12079571 1 85541164 85541164 intronic 0.927062 0.0328912201624376 GWAS of prostate cancer rs817482 1 85578057 85578057 intronic 0.617393 0.209438298855555 GWAS of prostate cancer rs4475769 1 85584149 85584149 intronic 0.303398 0.517987286409627 GWAS of prostate cancer rs1770691 1 85556791 85556791 intronic 0.301502 0.520709802641299 GWAS of prostate cancer rs6695223 1 85531711 85531711 intronic 0.277766 0.55632091524371 GWAS of prostate cancer rs709764 1 85560264 85560264 intronic 0.217876 0.6617906065670439 GWAS of prostate cancer rs817473 1 85590031 85590031 intronic 0.135198 0.869029732916486 GWAS of prostate cancer rs1037742 1 85539804 85539804 intronic 0.118711 0.92550903658071 GWAS of prostate cancer rs1026469 1 85568972 85568972 intronic 0.047194 1.3261132118007901 GWAS of prostate cancer rs1542427 1 85554402 85554402 intronic 0.015295 1.8154505186793002 GWAS of prostate cancer rs709767 1 85561954 85561954 intronic 0.014479 1.8392614318874199 GWAS of prostate cancer rs709783 1 85594466 85594466 exonic 0.998579 0.000617571347219405