PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ECT2 DCAF16 22990118 biogrid exp G G G G G G G G G G CUL4B DCAF16 21145461 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G DDA1 DCAF16 19295130 biogrid exp G G G G G GP G G GP G G G G G G GP G G G GP GP G G G GP GP G FGL1 DCAF16 26186194 biogrid exp G G G G G GP G G P G G G G G G G GP G G G G GP GP G G G GP GP G COPS5 DCAF16 21145461 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G DEF6 DCAF16 26186194 biogrid exp G G G P G G G G G G G G P G G G G G G G GP G RBPJ DCAF16 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SFRP4 DCAF16 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G GP G COPS6 DCAF16 19295130,21145461 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G CUL4A DCAF16 19295130,16949367,21145461 innatedb,biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PRMT6 DCAF16 23455924 biogrid,intact exp G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G GP GP G PRMT1 DCAF16 23455924 biogrid,intact exp G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G BARD1 DCAF16 22990118 biogrid exp G G P GP G G G P G GP P G G GP GP G LDLRAP1 DCAF16 26186194 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G G G GP G G G GP GP G ZBTB44 DCAF16 26186194 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G DDB1 DCAF16 16949367, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G DCAF4 DCAF16 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G DCAF12 DCAF16 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G G GP G G G GP G G DCAF10 DCAF16 25402006 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G GP G G DCAF7 DCAF16 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G DCAF17 DCAF16 25402006 pred G GP G G G G G GP G G G G G GP GP DCAF5 DCAF16 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G DCAF11 DCAF16 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G DCAF13 DCAF16 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G ERCC8 DCAF16 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RBX1 DCAF16 25402006 pred G G G G G GP G G G G G G G G G G GP G G G G GP G G G G G GP G DCAF6 DCAF16 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DCAF16 DTL 25402006 pred G G P G G P G P G G G GP TRPC4AP DCAF16 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G G GP G G G GP GP G DCAF8 DCAF16 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G GP GP G G G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q99728 Q9NXF7 affinity chromatography technology 22990118 physical association X 2 Q7L5N1 Q9NXF7 affinity chromatography technology 21145461 physical association X 2 Q7L5N1 Q9NXF7 affinity chromatography technology 19295130 physical association X 2 A0A024R7W9 Q9NXF7 affinity chromatography technology 21145461 physical association X 2 P0CG48 Q9NXF7 affinity chromatography technology 22505724 physical association X 2 P0CG48 Q9NXF7 affinity chromatography technology 23000965 physical association X 2 P0CG48 Q9NXF7 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q9NXF7 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q9NXF7 affinity chromatography technology 21906983 physical association X 2 Q9NXF7 B2RBV7 affinity chromatography technology 21145461 physical association X 2 Q9NXF7 Q13620-3 affinity chromatography technology 21145461 physical association X 2 Q9NXF7 B2RBV7 affinity chromatography technology 19295130 physical association X 2 Q9NXF7 Q9BW61 affinity chromatography technology 19295130 physical association X 2 Q9NXF7 Q16531 affinity chromatography technology 16949367 physical association X 2 Q9NXF7 B2RBV7 affinity chromatography technology 16949367 physical association X 2 Q9NXF7 Q16531 affinity chromatography technology 16949367 physical association X 2 Q3U1J4 Q9NXF7 affinity chromatography technology 20360068 physical association X 2 A0A087X1W2 Q9NXF7 two hybrid 23455924 direct interaction X 2 Q9NXF7 affinity chromatography technology 22190034 physical association X 2 Q96LA8 Q9NXF7 two hybrid 23455924 direct interaction X 2 Q9NXF7 Q9H8V3-4 affinity chromatography technology 22990118 physical association X 2 Q9NXF7 anti tag coimmunoprecipitation 22190034 association C 19 Q9NXF7 tandem affinity purification 20360068 physical association C 32 Q99873 Q9NXF7 two hybrid 23455924 physical association X 2 P04608 Q9NXF7 pull down 22190034 physical association X 2 Q96LA8 Q9NXF7 two hybrid 23455924 physical association X 2 Q9NXF7 P28808 two hybrid pooling approach 20711500 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9NXF7 Q5SW96 DCAF16 LDLRAP1 0.126 26186194 Q9NXF7 Q9H8V3 DCAF16 ECT2 0.126 22990118 Q9NXF7 Q8NCP5 DCAF16 ZBTB44 0.126 26186194 Q9NXF7 Q9H4E7 DCAF16 DEF6 0.126 26186194 Q9NXF7 P28808 DCAF16 LCRF 0.126 20711500 Q9NXF7 Q13619 DCAF16 CUL4A 0.332 21145461,16949367,19295130 Q9NXF7 Q6FHJ7 DCAF16 SFRP4 0.126 26186194 Q9NXF7 P04608 DCAF16 TAT 0.286 22190034 Q9NXF7 Q96LA8 DCAF16 PRMT6 0.332 23455924 Q9NXF7 Q99873 DCAF16 PRMT1 0.332 23455924 Q9NXF7 Q7L5N1 DCAF16 COPS6 0.236 19295130,21145461 Q9NXF7 Q3U1J4 DCAF16 DDB1 0.416 26496610,20360068 Q9NXF7 Q92905 DCAF16 COPS5 0.126 21145461 Q9NXF7 Q9BW61 DCAF16 DDA1 0.126 19295130 Q9NXF7 Q99728 DCAF16 BARD1 0.126 22990118 Q9NXF7 Q13620 DCAF16 CUL4B 0.126 21145461 Q9NXF7 Q06330 DCAF16 RBPJ 0.126 26186194 Q9NXF7 Q16531 DCAF16 DDB1 0.236 16949367 Q9NXF7 Q08830 DCAF16 FGL1 0.126 26186194