Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 2 29138009 rs6547892 A G rs6547892 9.92E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 A intron GWASdb_drug 2 29128322 rs6547889 T C rs6547889 2.40E-05 Urinary metabolites HPOID:0000079 DOID:557 T intron GWASdb_trait 2 29152456 rs1140697 A G rs1140697 7.56E-05 Serum metabolites HPOID:0011111 NA A cds-synon GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs4666141 2 29164022 29164022 intronic 0.940695 0.0265511643392414 GWAS of prostate cancer rs4577244 2 29120733 29120733 intronic 0.932215 0.0304839132412175

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000163811.11 WDR43 616195