PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CCT6A FYCO1 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DDX60 FYCO1 26496610 biogrid,intact exp GP GP G GP P G GP GP GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP P G ADO FYCO1 26496610 biogrid,intact exp G GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G TRUB2 FYCO1 26186194 biogrid exp G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G LMNA FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G APP FYCO1 21832049 biogrid exp G GP G G GP GP G G GP G G G G G G GP GP G GP G GP GP G G GP G G GP G FYCO1 MOV10 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G CCDC101 FYCO1 26186194 biogrid exp GP GP G G GP GP G G GP G GP G G G G G GP G G G GP G GP G G G GP GP G CCZ1 FYCO1 20562859 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FYCO1 FYCO1 20100911,20562859 innatedb,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RPA3 FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SASS6 FYCO1 26186194 biogrid exp GP G G GP P GP P P G G P GP P G GP GP GP G P GP RPA2 FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAP4 FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CCT2 FYCO1 26186194 biogrid exp GP GP G G GP GP G GP GP G G GP GP GP G GP GP G GP G GP GP G G GP GP GP GP G CCZ1B FYCO1 20562859 intact exp P P P P P P P P P P P P P P P P P P P P P P KIF5B FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CCT7 FYCO1 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CCAR1 FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FYCO1 CCDC68 26186194 biogrid exp GP GP P P G GP GP P GP GP GP GP GP GP P G GP GP P P GP GP GP GP G TECPR1 FYCO1 20562859 intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G SEC23B FYCO1 20562859 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TMPO FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAF1 FYCO1 16364241 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PPL FYCO1 26496610 biogrid,intact exp GP G G GP G G G GP GP GP G G G GP G GP G G GP GP G G GP G PAX6 FYCO1 26496610 biogrid,intact exp G GP P G P GP GP GP G P GP GP GP NOL9 FYCO1 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C18orf8 FYCO1 20562859 biogrid,intact exp G GP G G G G G G GP G GP G GP G G GP G GP G G G G G G GP G G GP G SEC24B FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G FOXK1 FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FYCO1 GOPC 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CCT3 FYCO1 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KIF23 FYCO1 20562859 biogrid exp P P G GP P P P P P P P P P P P P P P P P P P GP XPO1 FYCO1 26673895 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EMD FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TCP1 FYCO1 26186194 biogrid exp P P P P P P P P P P P P P P P P P P P P P P FYCO1 DTNA 26186194 biogrid exp GP GP G G G GP G GP GP G GP GP GP G G G GP G GP G P G GP GP G G GP GP G MEF2D FYCO1 20936779 i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RPA1 FYCO1 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MLYCD FYCO1 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G MON1B FYCO1 20562859 biogrid,intact exp GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP P G RFT1 FYCO1 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FYCO1 POLDIP3 26496610 biogrid,intact exp G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP G G G G GP GP GP G GP GP G IQCB1 FYCO1 21565611 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G KDM1A FYCO1 23455924 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G C17orf59 FYCO1 26186194 biogrid exp P P P P G P P P P P GP P P P P P GP G P P P PRMT6 FYCO1 23455924 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP G G GP GP GP GP G GP GP GP GP G GP GP G CCT6B FYCO1 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FYCO1 MAP1LC3B 20100911,23043107,20562859,24089205, 25402006 innatedb,biogrid,intact,dip exp, pred G GP G G GP GP G GP GP G GP G G G G GP GP G G G G G G GP GP G GP GP G FYCO1 MAP1LC3C 20562859, 25402006 intact exp, pred G G G FYCO1 GABARAPL1 20562859, 25402006 intact exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G G G GP G GP GP GP G GP GP G FYCO1 MAP1LC3A 23043107,20562859,22963397, 25402006 biogrid,intact exp, pred G GP G G G GP G G GP G G GP G G G GP GP G GP G G G G G GP G G GP G GABARAPL2 FYCO1 20562859, 25402006 intact exp, pred G GP G G GP GP G GP GP G GP G G G G GP GP G GP G G GP GP G GP G GP GP G GABARAP FYCO1 20562859, 25402006 intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PIK3C2A FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAB3GAP1 FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HADHA FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EEA1 FYCO1 23023127 pred GP GP G G GP GP G G GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP G NSMAF FYCO1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G STBD1 FYCO1 25402006 pred G G SAFB2 FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FYCO1 TMEM160 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TP53INP2 FYCO1 25402006 pred G G G G G G G G GP G G G G G G GP G G G G G G GP GP GP G GP G G RASSF5 FYCO1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G MTMR14 FYCO1 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G GP G GP G G GP GP G GP GP G MAP1LC3B2 FYCO1 25402006 pred P P P P P P P P P P P P STK4 FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RNF135 FYCO1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G TBC1D15 FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FYCO1 ATG4B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FYCO1 PINK1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAP1A FYCO1 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G G G G G G G G G SAFB FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NBR1 FYCO1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G RANBP6 FYCO1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G IPO5 FYCO1 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G MAP1B FYCO1 25402006 pred G GP G G G GP G G GP G GP G G G G G GP G GP G GP GP G G G G G GP G STK3 FYCO1 25402006 pred GP GP G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP G GP GP GP GP GP G TRIM22 FYCO1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KEAP1 FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FYCO1 ATG3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP GP GP GP G MAP1S FYCO1 25402006 pred GP G G G G G G GP GP G GP G GP GP G GP G GP GP G GP GP GP G GP GP GP GP G HADHB FYCO1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FYCO1 RAB3GAP2 25402006 pred P P P P P P P P P P P P P P P P P P P P P P SQSTM1 FYCO1 25402006 pred GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP GP GP GP GP GP GP GP G PRKCI FYCO1 25402006 pred GP GP G G G GP G G GP G GP G GP G G GP GP G GP G GP GP G G GP G GP GP G HNRNPA2B1 FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NEDD4 FYCO1 25402006 pred GP GP G GP P G GP GP GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G ZFYVE26 FYCO1 23023127 pred GP GP G G GP GP G G GP G G GP G GP G GP GP G P G GP GP G G GP G GP P G ATG7 FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G WDFY3 FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FYCO1 LUC7L2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G GBAS FYCO1 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9BQS8 P05067-7 pull down 21832049 direct interaction X 2 Q9BQS8 affinity chromatography technology 21565611 physical association X 2 Q9BQS8 O60341 affinity chromatography technology 23455924 physical association X 2 Q9BQS8 O60341 two hybrid 23455924 direct interaction X 2 Q9BQS8 P0CG48 affinity chromatography technology 24816145 physical association X 2 Q9BQS8 Q96DM3 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 P86790 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 Q8IX12 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 P85037 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 A4D105 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 P33176 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 P0CG48 affinity chromatography technology 21139048 physical association X 2 P15927 Q9BQS8 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 Q9H492 unspecified method 23043107 direct interaction X 2 Q9BQS8 Q658J6 unspecified method 23043107 direct interaction X 2 Q9BQS8 Q9H492 affinity chromatography technology 22963397 physical association X 2 Q9BQS8 Q96LA8 affinity chromatography technology 23455924 physical association X 2 Q9BQS8 Q96LA8 two hybrid 23455924 direct interaction X 2 Q9BQS8 L7RRS6 two hybrid 16364241 direct interaction X 2 Q9BQS8 Q7L1V2 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 P02545-5 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 A0A024RBH7 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 P27694 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 B4DJW8 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 O95487 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 P50402 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 Q02241-3 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 Q9H492 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 Q658J6 affinity chromatography technology 20562859 physical association X 2 Q9BQS8 tandem affinity purification 24089205 - C 8 Q9BQS8 Q658J6 tandem affinity purification 24089205 physical association X 2 Q9BQS8 anti tag coimmunoprecipitation 20562859 association C 20 Q9BQS8 anti tag coimmunoprecipitation 21565611 association C 171 Q9BQS8 P60520 pull down 20562859 direct interaction X 2 Q9BQS8 P60520 pull down 20562859 physical association X 2 Q9BQS8 Q7CLC1 two hybrid pooling approach 20711500 physical association X 2 Q9BQS8 O60341 anti tag coimmunoprecipitation 23455924 physical association X 2 Q9BQS8 O60341 two hybrid 23455924 physical association X 2 Q9BQS8 anti tag coimmunoprecipitation 20562859 association C 22 Q9BQS8 anti tag coimmunoprecipitation 20562859 association C 22 Q9BQS8 anti tag coimmunoprecipitation 20562859 association C 11 Q9BQS8 anti tag coimmunoprecipitation 20562859 physical association C 18 Q9BQS8 anti tag coimmunoprecipitation 20562859 physical association C 18 Q9BQS8 anti tag coimmunoprecipitation 20562859 physical association C 25 Q9BQS8 anti tag coimmunoprecipitation 20562859 association C 10 Q9BQS8 A0A024RAP5 pull down 20562859 direct interaction X 2 Q9BQS8 Q658J6 pull down 20562859 direct interaction X 2 Q9BQS8 O95166 pull down 20562859 direct interaction X 2 Q9BQS8 Q9BXW4 pull down 20562859 direct interaction X 2 Q9BQS8 A0A024RAP5 pull down 20562859 physical association X 2 Q9BQS8 O95166 pull down 20562859 physical association X 2 Q9BQS8 Q658J6 pull down 20562859 physical association X 2 Q9BQS8 Q9BXW4 pull down 20562859 physical association X 2 Q9BQS8 Q8BHN0 pull down 22796112 physical association X 2 Q9BQS8 Q96LA8 anti tag coimmunoprecipitation 23455924 physical association X 2 Q9BQS8 Q96LA8 two hybrid 23455924 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B KIF23 FYCO1 MI:0004(affinity chromatography technology) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_125226 prey bait APP FYCO1 MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_229393 prey bait CCZ1 FYCO1 MI:0004(affinity chromatography technology) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_125212 prey bait SEC23B FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125219|UniProt_106942 prey|prey bait|bait RPA2 FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125216|UniProt_106942 prey|prey bait|prey KDM1A FYCO1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid) 23455924 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(intact)|(intact) BIOGRID_297440|BIOGRID_274667|UniProt_129418|UniProt_129828 prey|prey|bait|prey bait|bait|prey|bait MON1B FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125214|UniProt_106942 prey|prey bait|bait PRMT6 FYCO1 MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 23455924 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact)|(biogrid) BIOGRID_297441|UniProt_129419|UniProt_129871|BIOGRID_274717 prey|bait|prey|prey bait|prey|bait|bait UBC FYCO1 MI:0004(affinity chromatography technology) 21139048 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_170686 bait prey FYCO1 MAP1LC3C MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact) UniProt_106843|UniProt_106716 prey|prey bait|bait TMPO FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125217|UniProt_106942 prey|prey bait|prey GABARAP FYCO1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact) UniProt_106570|UniProt_106801 bait|bait prey|prey RPA1 FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125218|UniProt_106942 prey|prey bait|prey FOXK1 FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125222|UniProt_106942 prey|prey bait|bait KIF5B FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125225|UniProt_106942 prey|prey bait|prey C18orf8 FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125211|UniProt_106942 prey|prey bait|bait CCAR1 FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125221|UniProt_106942 prey|prey bait|prey RPA3 FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125223|UniProt_106942 prey|prey bait|bait GABARAPL2 FYCO1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact) UniProt_106778|UniProt_106639 bait|bait prey|prey MAP4 FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125213|UniProt_106942 prey|prey bait|bait FYCO1 MAP1LC3A MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20562859,22963397,23043107 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid) UniProt_106928|UniProt_106878|UniProt_106889|BIOGRID_260161|BIOGRID_226184|BIOGRID_125367 prey|prey|prey|prey|prey|prey bait|prey|bait|bait|bait|bait FYCO1 MAP1LC3B MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20562859,23043107 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0914(association) (intact)|(intact)|(intact)|(biogrid)|(intact)|(intact)|(biogrid)|(intact)|(intact) UniProt_106879|UniProt_106864|UniProt_106929|BIOGRID_125393|UniProt_106820|UniProt_106679|BIOGRID_226185|UniProt_106890|UniProt_106885 prey|prey|prey|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait|bait|prey|bait EMD FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125224|UniProt_106942 prey|prey bait|prey FYCO1 GABARAPL1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact) UniProt_106751|UniProt_106608 prey|prey bait|bait SEC24B FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125220|UniProt_106942 prey|prey bait|prey IQCB1 FYCO1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 21565611 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0914(association) (intact)|(biogrid)|(intact) UniProt_205051|BIOGRID_257310|UniProt_113722 bait|bait|bait prey|prey|prey LMNA FYCO1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_125215|UniProt_106942 prey|prey bait|bait

PPI - HINT Gene A Gene B PMID Method Quality PPL FYCO1 26496610,26496610 0007,0004 HT SEC24B FYCO1 20562859,20562859 0007,0004 HT MLYCD FYCO1 26186194 0004 HT TRUB2 FYCO1 26186194 0004 HT LMNA FYCO1 20562859,20562859 0007,0004 HT RPA2 FYCO1 20562859,20562859 0007,0004 HT TCP1 FYCO1 26186194 0004 HT PAX6 FYCO1 26496610,26496610 0007,0004 HT RPA1 FYCO1 20562859,20562859 0007,0004 HT MAP4 FYCO1 20562859,20562859 0007,0004 HT KIF5B FYCO1 20562859,20562859 0007,0004 HT RPA3 FYCO1 20562859,20562859 0007,0004 HT CCT6A FYCO1 26186194 0004 HT TMPO FYCO1 20562859 0007 HT EMD FYCO1 20562859,20562859 0007,0004 HT GABARAPL2 FYCO1 20562859 0096 HT FOXK1 FYCO1 20562859,20562859 0007,0004 HT CCZ1B FYCO1 20562859 0004 HT CCZ1 FYCO1 20562859,20562859 0007,0004 HT KIF23 FYCO1 20562859 0004 HT IQCB1 FYCO1 21565611,21565611 0004,0007 HT SEC23B FYCO1 20562859,20562859 0007,0004 HT Q59G12 FYCO1 20562859 0004 HT Q59H77 FYCO1 26186194 0004 HT PCID2 FYCO1 20562859 0096 HT NOL9 FYCO1 26496610,26496610 0007,0004 HT DKFZP762B153 FYCO1 20562859,20100911,20562859,20100911 0096,0096,0004,0007 HT,LC SASS6 FYCO1 26186194 0004 HT MON1B FYCO1 20562859,20562859 0007,0004 HT TECPR1 FYCO1 20562859 0007 HT CCAR1 FYCO1 20562859,20562859 0007,0004 HT DDX60 FYCO1 26496610 0007 HT CCT6B FYCO1 26186194 0004 HT RFT1 FYCO1 26496610,26496610 0007,0004 HT C18ORF8 FYCO1 20562859,20562859 0007,0004 HT SGF29 FYCO1 26186194 0004 HT C17ORF59 FYCO1 26186194 0004 HT ADO FYCO1 26496610,26496610 0007,0004 HT CCT7 FYCO1 26186194 0004 HT FYCO1 FYCO1 20100911,20562859 0007,0007 LC,HT FYCO1 MAP1LC3C 20562859 0096 HT FYCO1 POLDIP3 26496610,26496610 0007,0004 HT FYCO1 MAP1LC3B 20562859,20562859,20562859,24089205 0096,0007,0004,0676 HT,LC FYCO1 GABARAPL1 20562859 0096 HT FYCO1 CCDC68 26186194 0004 HT FYCO1 MAP1LC3A 22963397,20562859,20562859 0004,0007,0004 LC,HT FYCO1 GOPC 26496610,26496610 0007,0004 HT FYCO1 Q9NXV7 26496610 0004 HT FYCO1 DTNA 26186194 0004 HT FYCO1 HEL-S-61 20562859 0004 HT FYCO1 HEL-S-100N 26186194 0004 HT PPL FYCO1 26496610,26496610 0007,0004 HT SEC24B FYCO1 20562859,20562859 0007,0004 HT MLYCD FYCO1 26186194 0004 HT TRUB2 FYCO1 26186194 0004 HT LMNA FYCO1 20562859,20562859 0007,0004 HT RPA2 FYCO1 20562859,20562859 0007,0004 HT TCP1 FYCO1 26186194 0004 HT PAX6 FYCO1 26496610,26496610 0007,0004 HT RPA1 FYCO1 20562859,20562859 0007,0004 HT MAP4 FYCO1 20562859,20562859 0007,0004 HT KIF5B FYCO1 20562859,20562859 0007,0004 HT RPA3 FYCO1 20562859,20562859 0007,0004 HT CCT6A FYCO1 26186194 0004 HT TMPO FYCO1 20562859 0007 HT EMD FYCO1 20562859,20562859 0007,0004 HT GABARAPL2 FYCO1 20562859 0096 HT FOXK1 FYCO1 20562859,20562859 0007,0004 HT CCZ1B FYCO1 20562859 0004 HT CCZ1 FYCO1 20562859,20562859 0007,0004 HT KIF23 FYCO1 20562859 0004 HT IQCB1 FYCO1 21565611,21565611 0004,0007 HT SEC23B FYCO1 20562859,20562859 0007,0004 HT Q59G12 FYCO1 20562859 0004 HT Q59H77 FYCO1 26186194 0004 HT PCID2 FYCO1 20562859 0096 HT NOL9 FYCO1 26496610,26496610 0007,0004 HT DKFZP762B153 FYCO1 20562859,20562859 0096,0004 HT SASS6 FYCO1 26186194 0004 HT MON1B FYCO1 20562859,20562859 0007,0004 HT TECPR1 FYCO1 20562859 0007 HT CCAR1 FYCO1 20562859,20562859 0007,0004 HT DDX60 FYCO1 26496610 0007 HT CCT6B FYCO1 26186194 0004 HT RFT1 FYCO1 26496610,26496610 0007,0004 HT C18ORF8 FYCO1 20562859,20562859 0007,0004 HT SGF29 FYCO1 26186194 0004 HT C17ORF59 FYCO1 26186194 0004 HT ADO FYCO1 26496610,26496610 0007,0004 HT CCT7 FYCO1 26186194 0004 HT FYCO1 FYCO1 20562859 0007 HT FYCO1 MAP1LC3C 20562859 0096 HT FYCO1 POLDIP3 26496610,26496610 0007,0004 HT FYCO1 MAP1LC3B 20562859,20562859,20562859 0096,0007,0004 HT FYCO1 GABARAPL1 20562859 0096 HT FYCO1 CCDC68 26186194 0004 HT FYCO1 MAP1LC3A 20562859,20562859 0007,0004 HT FYCO1 GOPC 26496610,26496610 0007,0004 HT FYCO1 Q9NXV7 26496610 0004 HT FYCO1 DTNA 26186194 0004 HT FYCO1 HEL-S-61 20562859 0004 HT FYCO1 HEL-S-100N 26186194 0004 HT DKFZP762B153 FYCO1 20100911,20100911 0096,0007 LC FYCO1 FYCO1 20100911 0007 LC FYCO1 MAP1LC3B 24089205 0676 LC FYCO1 MAP1LC3A 22963397 0004 LC KDM1A FYCO1 23455924,23455924,23455924 0018,0007,0004 HT RAF1 FYCO1 16364241 0018 LC PRMT6 FYCO1 23455924,23455924,23455924 0018,0007,0004 HT FYCO1 MAP1LC3B 26468287 0114 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9HCE1 Q9BQS8 MOV10 FYCO1 0.126 22658674 Q9BQS8 O60341 FYCO1 KDM1A 0.49 23455924 Q9H2F9 Q9BQS8 CCDC68 FYCO1 0.126 26186194 Q9BQS8 Q6P5F9 FYCO1 XPO1 0.126 26673895 Q9BQS8 Q8BHN0 FYCO1 PPM1L 0.21 22796112 Q9BQS8 P04049 FYCO1 RAF1 0.309 16364241 Q9BQS8 O95900 FYCO1 TRUB2 0.126 26186194 Q9BQS8 Q96LA8 FYCO1 PRMT6 0.49 23455924 Q9BQS8 P42166 FYCO1 TMPO 0.236 20562859 Q9BQS8 O95166 FYCO1 GABARAP 0.286 20562859 Q9BQS8 P35244 FYCO1 RPA3 0.236 20562859 Q9BQS8 P15927 FYCO1 RPA2 0.236 20562859 Q9BQS8 O95487 FYCO1 SEC24B 0.236 20562859 Q9BQS8 P02545 FYCO1 LMNA 0.236 20562859 Q9BQS8 P33176 FYCO1 KIF5B 0.236 20562859 Q9BQS8 P27694 FYCO1 RPA1 0.236 20562859 Q9BQS8 P27816 FYCO1 MAP4 0.236 20562859 Q9BQS8 Q8IX12 FYCO1 CCAR1 0.236 20562859 Q9BQS8 P85037 FYCO1 FOXK1 0.236 20562859 Q9BQS8 P50402 FYCO1 EMD 0.236 20562859 Q9BQS8 P60520 FYCO1 GABARAPL2 0.286 20562859 Q9BQS8 Q7L1V2 FYCO1 MON1B 0.236 20562859 Q9BQS8 Q15437 FYCO1 SEC23B 0.236 20562859 Q9BQS8 Q5SY16 FYCO1 NOL9 0.236 26496610 Q9BQS8 Q8IY21 FYCO1 DDX60 0.236 26496610 Q9BQS8 Q96DM3 FYCO1 C18ORF8 0.236 20562859 Q9HD26 Q9BQS8 GOPC FYCO1 0.236 26496610 Q9BQS8 Q96SZ5 FYCO1 ADO 0.236 26496610 Q9BY77 Q9BQS8 POLDIP3 FYCO1 0.236 26496610 Q9BXW4 Q9BQS8 MAP1LC3C FYCO1 0.286 20562859 Q9BQS8 Q15051 FYCO1 IQCB1 0.236 21565611 Q9BQS8 P26367 FYCO1 PAX6 0.236 26496610 Q9H492 Q9BQS8 MAP1LC3A FYCO1 0.636 20562859,22963397,23043107 Q9BQS8 Q96ES7 FYCO1 CCDC101 0.126 26186194 Q9BQS8 Q96GS4 FYCO1 C17ORF59 0.126 26186194 Q9BQS8 B5MDE0 FYCO1 B5MDE0 0.126 26496610 Q9BQS8 K7EKI8 FYCO1 PPL {ECO:0000313|ENSEMBL:ENSP00000465640} 0.126 26496610 Q9BQS8 O60437 FYCO1 PPL 0.126 26496610 Q9BQS8 O95766 FYCO1 CCZ1 0.126 20562859 Q9BQS8 O95822 FYCO1 MLYCD 0.126 26186194 Q9BQS8 P05067 FYCO1 APP 0.183 21832049 Q9BQS8 P17987 FYCO1 TCP1 0.126 26186194 Q9BQS8 P40227 FYCO1 CCT6A 0.126 26186194 Q9BQS8 P42167 FYCO1 TMPO 0.126 20562859 Q9BQS8 P49368 FYCO1 CCT3 0.126 26186194 Q9BQS8 P78371 FYCO1 CCT2 0.126 26186194 Q9BQS8 P86790 FYCO1 CCZ1B 0.126 20562859 Q9BQS8 P86791 FYCO1 CCZ1 0.126 20562859 Q9BQS8 Q02241 FYCO1 KIF23 0.126 20562859 Q9BQS8 Q6UVJ0 FYCO1 SASS6 0.126 26186194 Q9BQS8 Q7CLC1 FYCO1 CPXA 0.126 20711500 Q9BQS8 Q7Z6L1 FYCO1 TECPR1 0.126 20562859 Q9BQS8 Q92526 FYCO1 CCT6B 0.126 26186194 Q9BQS8 Q96AA3 FYCO1 RFT1 0.126 26496610 Q9BQS8 Q99832 FYCO1 CCT7 0.126 26186194 Q9BQS8 Q9BQS8 FYCO1 FYCO1 0.155 20562859 Q9GZQ8 Q9BQS8 MAP1LC3B FYCO1 0.671 20562859,23043107 Q9H0R8 Q9BQS8 GABARAPL1 FYCO1 0.286 20562859 Q9Y4J8 Q9BQS8 DTNA FYCO1 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 XPO1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database KDM1A FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database PPL FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database OFD1 FYCO1 MI:0362 inference MI:0461 interaction database GABARAP FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database SEC24B FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database MLYCD FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database TRUB2 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database LMNA FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database RAF1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database APP FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database UBC FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database RPA2 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database TCP1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database TAF1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database PAX6 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database RPA1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database MAP4 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database KIF5B FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database RPA3 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database CCT6A FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database HNF4A FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database TMPO FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database TMPO FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database MAP1B FYCO1 MI:0362 inference MI:0461 interaction database CCT3 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database EMD FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database GABARAPL2 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database CCT2 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database FOXK1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database CCZ1B FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database CCZ1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database KIF23 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database SQSTM1 FYCO1 MI:0362 inference MI:0461 interaction database KEAP1 FYCO1 MI:0362 inference MI:0461 interaction database IQCB1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database PCM1 FYCO1 MI:0362 inference MI:0461 interaction database SEC23B FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database PPM1L FYCO1 MI:0362 inference MI:0461 interaction database NOL9 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database SASS6 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database MON1B FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database TECPR1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database CCAR1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database DDX60 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database CCT6B FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database RFT1 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database C18orf8 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database SGF29 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database C17orf59 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database PRMT6 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database ADO FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database CCT7 FYCO1 MI:0045 experimental interaction detection MI:0461 interaction database FYCO1 MAP1LC3C MI:0045 experimental interaction detection MI:0461 interaction database FYCO1 POLDIP3 MI:0045 experimental interaction detection MI:0461 interaction database FYCO1 MAP1LC3B MI:0045 experimental interaction detection MI:0461 interaction database FYCO1 KLC2 MI:0362 inference MI:0461 interaction database FYCO1 GABARAPL1 MI:0045 experimental interaction detection MI:0461 interaction database FYCO1 CCDC68 MI:0045 experimental interaction detection MI:0461 interaction database FYCO1 MAP1LC3A MI:0045 experimental interaction detection MI:0461 interaction database FYCO1 MOV10 MI:0045 experimental interaction detection MI:0461 interaction database FYCO1 GOPC MI:0045 experimental interaction detection MI:0461 interaction database FYCO1 CEP131 MI:0362 inference MI:0461 interaction database FYCO1 DTNA MI:0045 experimental interaction detection MI:0461 interaction database