PTM - CPLM Gene Name UniProt ID Type Position Code RNF123; KPC1; FP1477 Q5XPI4 Ubiquitination 530 K RNF123; KPC1; FP1477 Q5XPI4 Ubiquitination 806 K RNF123; KPC1; FP1477 Q5XPI4 Ubiquitination 814 K RNF123; KPC1; FP1477 Q5XPI4 Ubiquitination 906 K RNF123; KPC1; FP1477 Q5XPI4 Ubiquitination 467 K RNF123; KPC1; FP1477 Q5XPI4 Ubiquitination 473 K RNF123; KPC1; FP1477 Q5XPI4 Ubiquitination 515 K RNF123; KPC1; FP1477 Q5XPI4 Ubiquitination 533 K RNF123; KPC1; FP1477 Q5XPI4 Ubiquitination 617 K

PTM - dbPAF Gene Name UniProt ID Position Type Species RNF123; KPC1; FP1477 Q5XPI4 11 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 126 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 127 T Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 128 T Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 131 Y Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 1312 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 14 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 15 Y Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 18 T Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 19 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 437 Y Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 610 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 675 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 677 T Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 686 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 694 T Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 700 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 702 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 709 T Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 711 S Homo sapiens(Human) RNF123; KPC1; FP1477 Q5XPI4 9 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q5XPI4 K4-ac Acetylation ____MASkGAGMsFs Q5XPI4 K13-ac Acetylation AGMsFsRksyRLtsD Q5XPI4 K814-ac Acetylation SQKVFSEkLDHLSRR Q5XPI4 R306-m1 Methylation DKESSKWrLRGQPTV Q5XPI4 K991-m1 Methylation TRLPHLLktkLEDAN Q5XPI4 K993-m1 Methylation LPHLLktkLEDANLP Q5XPI4 R1131-m1 Methylation AERNLFDrVVTLRLP Q5XPI4 S9-p Phosphorylation ASkGAGMsFsRksyR Q5XPI4 S11-p Phosphorylation kGAGMsFsRksyRLt Q5XPI4 S14-p Phosphorylation GMsFsRksyRLtsDA Q5XPI4 Y15-p Phosphorylation MsFsRksyRLtsDAE Q5XPI4 T18-p Phosphorylation sRksyRLtsDAEKSR Q5XPI4 S19-p Phosphorylation RksyRLtsDAEKSRV Q5XPI4 S126-p Phosphorylation SNFGTIRsttCVyKG Q5XPI4 T127-p Phosphorylation NFGTIRsttCVyKGK Q5XPI4 T128-p Phosphorylation FGTIRsttCVyKGKW Q5XPI4 Y131-p Phosphorylation IRsttCVyKGKWLYE Q5XPI4 S610-p Phosphorylation QRLGGLLsHLRKTLk Q5XPI4 S674-p Phosphorylation LPRPGWLssPtLGRA Q5XPI4 S675-p Phosphorylation PRPGWLssPtLGRAN Q5XPI4 T677-p Phosphorylation PGWLssPtLGRANRF Q5XPI4 S686-p Phosphorylation GRANRFLsTAAVSLM Q5XPI4 T694-p Phosphorylation TAAVSLMtPRRPLsT Q5XPI4 S700-p Phosphorylation MtPRRPLsTsEKVKV Q5XPI4 S702-p Phosphorylation PRRPLsTsEKVKVRT Q5XPI4 S711-p Phosphorylation KVKVRTLsVEQRTRE Q5XPI4 Y983-p Phosphorylation GCGFGYRyTRLPHLL Q5XPI4 T992-p Phosphorylation RLPHLLktkLEDANL Q5XPI4 S1312-p Phosphorylation ANTSTTSsAA_____ Q5XPI4 K33-ub Ubiquitination VTGIVQEkLLNDYLN Q5XPI4 K467-ub Ubiquitination HCSSREGkESTEMkE Q5XPI4 K473-ub Ubiquitination GkESTEMkEETAEER Q5XPI4 K515-ub Ubiquitination LKLLLDNkDDNGGEA Q5XPI4 K530-ub Ubiquitination SRYIFLTkFRkFLQE Q5XPI4 K533-ub Ubiquitination IFLTkFRkFLQENAS Q5XPI4 K617-ub Ubiquitination sHLRKTLkDDLASKA Q5XPI4 K806-ub Ubiquitination DILAELTkSQKVFSE Q5XPI4 K814-ub Ubiquitination SQKVFSEkLDHLSRR Q5XPI4 K906-ub Ubiquitination RLAAILAkHFADARI Q5XPI4 K1286-ub Ubiquitination NQHLMNNkDCFFCKT

PTM - dbPTM UniProt ID Position Code Type Resources References Q5XPI4 467 K Ubiquitylation Phosphositeplus.1010730 21906983 Q5XPI4 473 K Ubiquitylation Phosphositeplus.1010730 21906983 Q5XPI4 515 K Ubiquitylation Phosphositeplus.1010730 21906983 Q5XPI4 530 K Ubiquitylation Phosphositeplus.1010730 21890473 Q5XPI4 533 K Ubiquitylation Phosphositeplus.1010730 21906983 Q5XPI4 617 K Ubiquitylation Phosphositeplus.1010730 21906983 Q5XPI4 814 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q5XPI4 906 K Ubiquitylation Phosphositeplus.1010730 21890473 Q5XPI4 675 S Phosphorylation Phosphositeplus.1010730 19664994 Q5XPI4 675 S Phosphorylation HPRD 9.0 19651622,19664994

PTM - HPRD Symbol Position Code Type References RNF123 675 S Phosphorylation 19651622,19664994

PTM - UniProt UniProt ID Position Type PMIDs Q5XPI4 2 N-acetylalanine 22814378

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type RNF123 IPI00335085 Y 437 RSVVFFpYIKSPLR phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 63891 121971 - K Ubiquitination 21987572 63891 121971 - K Ubiquitination 21139048 63891 121971 - K Ubiquitination 21890473 63891 121971 - K Ubiquitination 21906983 63891 121971 - K Ubiquitination 22505724 63891 121971 - K Ubiquitination 23287719 63891 121971 - K Ubiquitination 23000965 63891 121971 - K Ubiquitination 24816145

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID RNF123 Homo sapiens (Human) 10 "10,LAAILAKHFADAR" 10:21890473 RNF123 Homo sapiens (Human) 18 "18,LAAILAKHFADAR" 18:21890473 RNF123 Homo sapiens (Human) 533; 473; 515; 530; 617; 467 "533,FLTKFRKFLQENA; 473,KESTEMKEETAEE; 515,KLLLDNKDDNGGE; 530,RYIFLTKFRKFLQ; 617,HLRKTLKDDLASK; 467,CSSREGKESTEMK" 533:21906983; 473:21906983; 515:21906983; 530:21890473; 617:21906983; 467:21906983 RNF123 Homo sapiens (Human) 533; 806; 906; 473; 515; 530; 814; 617; 467 "533,FLTKFRKFLQENA; 806,ILAELTKSQKVFS; 906,LAAILAKHFADAR; 473,KESTEMKEETAEE; 515,KLLLDNKDDNGGE; 530,RYIFLTKFRKFLQ; 814,QKVFSEKLDHLSR; 617,HLRKTLKDDLASK; 467,CSSREGKESTEMK" "533:21906983; 806:21890473; 906:21890473; 473:21906983; 515:21906983; 530:21890473; 814:21890473,21906983; 617:21906983; 467:21906983" RNF123 Homo sapiens (Human) 533; 806; 906; 473; 515; 530; 814; 617; 467 "533,FLTKFRKFLQENA; 806,ILAELTKSQKVFS; 906,LAAILAKHFADAR; 473,KESTEMKEETAEE; 515,KLLLDNKDDNGGE; 530,RYIFLTKFRKFLQ; 814,QKVFSEKLDHLSR; 617,HLRKTLKDDLASK; 467,CSSREGKESTEMK" "533:21906983; 806:21890473; 906:21890473; 473:21906983; 515:21906983; 530:21890473; 814:21890473,21906983; 617:21906983; 467:21906983" RNF123 Homo sapiens (Human) 533; 806; 906; 473; 515; 530; 814; 617; 467 "533,FLTKFRKFLQENA; 806,ILAELTKSQKVFS; 906,LAAILAKHFADAR; 473,KESTEMKEETAEE; 515,KLLLDNKDDNGGE; 530,RYIFLTKFRKFLQ; 814,QKVFSEKLDHLSR; 617,HLRKTLKDDLASK; 467,CSSREGKESTEMK" 533:21906983; 806:21890473; 906:21890473; 473:21906983; 515:21906983; 530:21890473; 814:21890473; 617:21906983; 467:21906983 RNF123 Homo sapiens (Human) 668; 327; 321; 660; 384 "668,QKVFSEKLDHLSR; 327,KESTEMKEETAEE; 321,CSSREGKESTEMK; 660,ILAELTKSQKVFS; 384,RYIFLTKFRKFLQ" 668:21890473; 327:21906983; 321:21906983; 660:21890473; 384:21890473