Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 4 175162649 rs7681841 C T rs7681841 7.80E-06 Urinary metabolites HPOID:0000079 DOID:557 T intron GWASdb_trait 4 175168083 rs6824643 G A rs6824643 7.57E-05 Amyotrophic Lateral Sclerosis HPOID:0007354 DOID:332 G intron GWASdb_trait 4 175168153 rs6851312 A G rs6851312 7.34E-05 Amyotrophic Lateral Sclerosis HPOID:0007354 DOID:332 A intron GWASdb_trait 4 175168153 rs6851312 A G rs6851312 1.87E-04 Lung function (forced expiratory volume in 1 second to forced vital capacity ratio) HPOID:0002088 DOID:850 A intron GWASdb_trait 4 175183493 rs10520276 T C rs10520276 2.72E-04 Amyotrophic Lateral Sclerosis HPOID:0007354 DOID:332 T intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000164117.13 FBXO8 605649