PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HERC2 MIOS 25476789 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAE1 MIOS 19615732 biogrid exp GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP G G GP GP GP GP GP G SEC13 MIOS 26186194 biogrid exp GP GP G G G GP G GP GP G G G G G G GP GP G GP G GP GP GP G GP GP GP G G DOK3 MIOS 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G RFPL2 MIOS 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G NTRK1 MIOS 25921289 biogrid exp P P P G P P P P P P P P P P P P P P P MIOS HECW2 24163370 biogrid exp GP GP G G G GP G GP GP G GP G GP G G P GP P GP G GP GP GP GP GP G GP GP MCM7 MIOS 23764002 intact exp GP GP G G G G G G GP G G G G GP G GP G GP G G GP GP GP G GP G GP GP G GATSL3 MIOS 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G MIOS KLHL20 26186194 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CHM MIOS 19615732 intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RFPL4B MIOS 26186194 biogrid exp P P P P P P P P P P P P SEH1L MIOS 26496610 biogrid,intact exp, ortho G GP G G G GP G G GP G G G GP G G GP GP G GP G GP GP G G GP G GP GP G DDHD2 MIOS ortho GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G CUL1 MIOS 25402006 pred GP G G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G GNAI3 MIOS 23023127 pred G GP G G G GP G GP GP G G G GP G G GP GP G GP G G G G G GP G GP GP G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B RAE1 MIOS MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_120491 bait prey MIOS HECW2 MI:0004(affinity chromatography technology) 24163370 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_294072 prey bait UBC MIOS MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21890473,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_174800|BIOGRID_167859|BIOGRID_268835 bait|bait|bait prey|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality RFPL2 MIOS 26186194 0004 HT CHM MIOS 19615732 0007 HT SEC13 MIOS 26186194 0004 HT RAE1 MIOS 19615732 0004 HT RFPL4B MIOS 26186194 0004 HT DOK3 MIOS 26186194 0004 HT GATSL3 MIOS 26186194,26972053 0004,0004 HT,LC SEH1L MIOS 26496610,26496610 0007,0004 HT MIOS AIPL1 27173435 0676 HT MIOS KLHL20 26186194 0004 HT RFPL2 MIOS 26186194 0004 HT CHM MIOS 19615732 0007 HT SEC13 MIOS 26186194 0004 HT RAE1 MIOS 19615732 0004 HT RFPL4B MIOS 26186194 0004 HT DOK3 MIOS 26186194 0004 HT GATSL3 MIOS 26186194 0004 HT SEH1L MIOS 26496610,26496610 0007,0004 HT MIOS AIPL1 27173435 0676 HT MIOS KLHL20 26186194 0004 HT GATSL3 MIOS 26972053 0004 LC WDYHV1 MIOS 27107012,27107012 1356,2215 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9NXC5 Q5T1M5 MIOS FKBP15 0.126 unassigned1312 Q9NXC5 P24386 MIOS CHM 0.126 19615732 Q9NXC5 Q9HBE1 MIOS PATZ1 0.126 unassigned1312 Q9NXC5 O76074 MIOS PDE5A 0.126 unassigned1312 Q9NXC5 Q7L523 MIOS RRAGA 0.21 23723238 Q9NXC5 Q8WTX7 MIOS GATSL3 0.454 26972053,26186194 Q9NXC5 Q9HB90 MIOS RRAGC 0.21 23723238 Q9NXC5 Q9H6Z9 MIOS EGLN3 0.126 26972000 Q9Y2M5 Q9NXC5 KLHL20 MIOS 0.126 26186194 Q9NXC5 Q6PJI9 MIOS WDR59 0.21 26972053 Q9NXC5 O75678 MIOS RFPL2 0.126 26186194 Q9NXC5 Q6ZWI9 MIOS RFPL4B 0.126 26186194 Q9NXC5 Q7L591 MIOS DOK3 0.126 26186194 Q9NXC5 P04629 MIOS NTRK1 0.126 25921289 Q9NXC5 O95684 MIOS FGFR1OP 0.126 unassigned1312 Q9NXC5 O95714 MIOS HERC2 0.126 25476789 Q9NZN9 Q9NXC5 AIPL1 MIOS 0.236 27173435,unassigned1312 Q9NXC5 Q96S15 MIOS WDR24 0.309 23723238,unassigned1312 Q9NXC5 Q96EE3 MIOS SEH1L 0.236 26496610 Q9NXC5 P58043 MIOS SESN2 0.236 26496610 Q9NXC5 Q96HA8 MIOS WDYHV1 0.236 27107012 Q9P2P5 Q9NXC5 HECW2 MIOS 0.126 24163370 Q9NXC5 P33993 MIOS MCM7 0.126 23764002 Q9UNN5 Q9NXC5 FAF1 MIOS 0.126 26389662 Q9NXC5 P78406 MIOS RAE1 0.126 19615732 Q9NXC5 A6NHX0 MIOS GATSL2 0.376 26972053 Q9NXC5 O00267 MIOS SUPT5H 0.126 unassigned1312 Q9NXC5 P54132 MIOS BLM 0.126 unassigned1312 Q9NXC5 P55735 MIOS SEC13 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 RFPL2 MIOS MI:0045 experimental interaction detection MI:0461 interaction database HERC2 MIOS MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 MIOS MI:0045 experimental interaction detection MI:0461 interaction database UBC MIOS MI:0045 experimental interaction detection MI:0461 interaction database CHM MIOS MI:0045 experimental interaction detection MI:0461 interaction database MCM7 MIOS MI:0045 experimental interaction detection MI:0461 interaction database SEC13 MIOS MI:0045 experimental interaction detection MI:0461 interaction database SESN2 MIOS MI:0362 inference MI:0461 interaction database SESN3 MIOS MI:0362 inference MI:0461 interaction database RAE1 MIOS MI:0045 experimental interaction detection MI:0461 interaction database RFPL4B MIOS MI:0045 experimental interaction detection MI:0461 interaction database RRAGA MIOS MI:0045 experimental interaction detection MI:0461 interaction database DOK3 MIOS MI:0045 experimental interaction detection MI:0461 interaction database GATSL3 MIOS MI:0045 experimental interaction detection MI:0461 interaction database SEH1L MIOS MI:0045 experimental interaction detection MI:0461 interaction database WDYHV1 MIOS MI:0045 experimental interaction detection MI:0461 interaction database WDR24 MIOS MI:0045 experimental interaction detection MI:0461 interaction database RRAGC MIOS MI:0045 experimental interaction detection MI:0461 interaction database MIOS AIPL1 MI:0045 experimental interaction detection MI:0461 interaction database MIOS HECW2 MI:0045 experimental interaction detection MI:0461 interaction database MIOS FAF1 MI:0045 experimental interaction detection MI:0461 interaction database MIOS KLHL20 MI:0045 experimental interaction detection MI:0461 interaction database MIOS SESN1 MI:0362 inference MI:0461 interaction database