PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PTGES3 USP49 25036637 intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP G P G GP GP GP G GP GP GP GP G COPA USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP G GP GP GP GP G F7 USP49 19615732 biogrid,intact exp P GP G G GP GP G GP GP G GP GP GP GP G P GP G P G GP P GP GP GP G GP GP G USP49 SLC39A7 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP G GP GP GP GP G USP49 YARS2 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G G GP GP GP GP GP GP GP CETN3 USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP G P G GP GP GP GP GP GP GP GP G USP49 RUVBL1 23824326 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP G GP G GP GP G MCM6 USP49 19615732 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP G P G GP GP GP GP GP GP GP GP G USP49 STUB1 25036637 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G HSF2 USP49 25036637 intact exp G G G G G G G G G G G G G G G G G G G G G G G G GP G USP49 DICER1 19615732 biogrid,intact exp GP G G G GP GP G GP GP G GP G G GP G GP GP G P G GP G GP GP GP GP GP GP G UBR5 USP49 19615732 biogrid,intact exp GP G G G G GP G G GP G GP GP GP GP G G GP G G GP G G G G G GP GP G USP49 SUGT1 25036637 intact exp G G G G G G G GP GP G GP G G G G GP G G P G G G G GP GP G GP GP G USP49 MED8 14576168 hprd exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G CETN2 USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G USP49 PPP6R1 19615732 biogrid,intact exp GP GP G G GP G G G GP G GP GP GP G G GP G G P G GP G GP GP GP GP GP GP G CDC37 USP49 25036637 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G IPO7 USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP G GP GP GP GP G USP49 SHCBP1 19615732 biogrid,intact exp P G GP P P P GP P P P P P P P GP USP49 USP44 19615732 biogrid,intact exp P P P P P P P P P P P P P G P P P P P P GP USP49 ANKRD52 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP G P G G GP GP G P G P GP GP GP GP GP GP G HIST2H2BE USP49 23824326 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G HSPA8 USP49 25036637 intact exp P P P P P P P P P P P P P P P P USP49 NUDCD3 25036637 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G PPM1G USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G USP49 MED18 12584197 hprd exp P P P P P P P P P P P P P P P KRR1 USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G G GP G GP GP GP GP GP GP G HSF1 USP49 25036637 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G PPP6R2 USP49 19615732 biogrid,intact exp G GP G G G G G GP GP G GP G G G G GP G G P G G G G GP GP G GP GP G FKBP6 USP49 25036637 intact exp GP G G P G P P P P G G P GP G USP49 MED17 14576168 hprd exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G LRPPRC USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G HADHA USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G ANKRD28 USP49 19615732 biogrid,intact exp G GP G G G GP G G GP G G G GP G G G GP G G GP G G GP G G GP GP G PPP6R3 USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G STIP1 USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G PDCD2 USP49 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G USP49 HUWE1 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G USP49 TRIM35 23105109 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP P GP GP GP GP G CETN1 USP49 19615732 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP G GP GP G P G P GP GP GP GP GP GP GP G HSP90AA1 USP49 25036637 intact exp GP GP G G G GP G G GP G G G G G G G GP G G GP G G G G G G GP G USP49 STAMBPL1 19615732 biogrid,intact exp G GP G G GP GP G GP GP G GP G GP GP G GP GP G P G P GP GP GP GP GP GP GP RPN1 USP49 19615732 biogrid,intact exp G GP G G GP GP G GP GP G G GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G USP49 NUP85 19615732 biogrid,intact exp, ortho GP GP G G G GP G GP GP G GP GP GP GP G GP GP G P G GP G GP GP GP GP GP GP G SHPRH USP49 19615732 biogrid,intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G PRKACA USP49 19615732 biogrid,intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G PPP5C USP49 25036637,19615732 biogrid,intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G USP49 CACYBP 25036637 intact exp, ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP G P G GP GP GP G GP GP GP GP G USP49 AARSD1 25036637 intact exp, ortho P P P P P P P P P P P P P P P P P USP49 IPO9 19615732 biogrid,intact exp, ortho G GP G G G G G G GP G GP G G G G GP G G G G G G G GP G G GP G PSMC5 USP49 23824326 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G HSP90AB1 USP49 25036637 intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G USP49 RBCK1 23105109 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G FKBP5 USP49 25036637,19615732 biogrid,intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G ELANE USP49 23023127 pred G GP G G USP49 USP33 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP G GP GP G SUMO2 USP49 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G WWP2 USP49 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP G GP GP G NEDD4 USP49 23023127 pred GP GP G GP P G GP GP GP G GP GP G GP GP G P G GP GP GP GP GP GP GP P G USP5 USP49 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP G GP GP GP GP GP G USP49 TRIM63 23023127 pred G G G G PLG USP49 23023127 pred P P G G P P P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q70CQ1 Q8K2C9 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 Q9HAV2 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 A0A024R7B7 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 A0A024R904 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 A0A024RB32 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 Q9BTE6-2 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 anti tag coimmunoprecipitation 19615732 physical association C 33 Q70CQ1 Q13451 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 Q6PK50 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 Q03933 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 Q8IVD9 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 Q96BE0 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 K9JA46 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 O75344 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 Q9UNE7 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q70CQ1 Q9BPW0 luminescence based mammalian interactome mapping 25036637 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B USP49 ANKRD52 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120866|UniProt_100679 bait|bait prey|prey USP49 MED8 MI:0492(in vitro) 14576168 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_14547 - - USP49 STAMBPL1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120358|UniProt_100650 prey|prey bait|bait KRR1 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120238|UniProt_100679 prey|prey bait|bait USP49 IPO9 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120552|UniProt_100679 bait|bait prey|prey HADHA USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119510|UniProt_100679 prey|prey bait|bait PPP6R3 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120526|UniProt_100679 prey|prey bait|bait RPN1 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119779|UniProt_100679 prey|prey bait|bait COPA USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119405|UniProt_100679 prey|prey bait|bait MCM6 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119585|UniProt_100679 prey|prey bait|bait CETN1 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119392|UniProt_100679 prey|prey bait|bait USP49 HUWE1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120118|UniProt_100679 bait|bait prey|prey PPM1G USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119671|UniProt_100679 prey|prey bait|bait UBR5 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120450|UniProt_100679 prey|prey bait|bait USP49 TRIM35 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248233 bait prey USP49 DICER1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120321|UniProt_100679 bait|bait prey|prey PRKACA USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119680|UniProt_100679 prey|prey bait|bait USP49 PPP6R1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120261|UniProt_100679 bait|bait prey|prey ANKRD28 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120299|UniProt_100679 prey|prey bait|bait USP49 LRPPRC MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_120130 bait prey CETN3 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119395|UniProt_100679 prey|prey bait|bait STIP1 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120220|UniProt_100679 prey|prey bait|bait PSMC5 USP49 MI:0415(enzymatic study)|MI:0415(enzymatic study) 23824326 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_283197|BIOGRID_283199 prey|prey bait|bait PPP6R2 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120088|UniProt_100679 prey|prey bait|bait USP49 YARS2 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120431|UniProt_100679 bait|bait prey|prey USP49 RUVBL1 MI:0415(enzymatic study)|MI:0415(enzymatic study) 23824326 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_283196|BIOGRID_283198 bait|bait prey|prey USP49 SLC39A7 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119884|UniProt_100679 bait|bait prey|prey USP49 MED17 MI:0492(in vitro) 14576168 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_12676 - - HIST2H2BE USP49 MI:0415(enzymatic study) 23824326 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_283195 prey bait CETN2 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119393|UniProt_100679 prey|prey bait|bait USP49 RBCK1 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248234 bait prey USP49 MED18 MI:0492(in vitro) 12584197 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_15458 - - USP49 NUP85 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120680|UniProt_100679 bait|bait prey|prey FKBP5 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119474|UniProt_100679 prey|prey bait|bait PDCD2 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119631|UniProt_100679 prey|prey bait|bait PPP5C USP49 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100679|BIOGRID_119676 prey|prey bait|bait SHPRH USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120861|UniProt_100679 prey|prey bait|bait IPO7 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120175|UniProt_100679 prey|prey bait|bait USP49 SHCBP1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120673|UniProt_100679 bait|bait prey|prey USP49 USP44 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100679|BIOGRID_120716 bait|bait prey|prey F7 USP49 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119466|UniProt_100679 prey|prey bait|bait

PPI - HINT Gene A Gene B PMID Method Quality B3KMJ7 USP49 19615732 0004 HT E9KL44 USP49 19615732 0004 HT ANKRD28 USP49 19615732,19615732 0004,0007 HT CETN3 USP49 19615732,19615732 0004,0007 HT PPM1G USP49 19615732,19615732 0004,0007 HT PPP6R2 USP49 19615732,19615732 0004,0007 HT UBR5 USP49 19615732,19615732 0004,0007 HT IPO7 USP49 19615732,19615732 0004,0007 HT RPN1 USP49 19615732,19615732 0004,0007 HT F7 USP49 19615732,19615732 0004,0007 HT PRKACA USP49 19615732,19615732 0004,0007 HT STIP1 USP49 19615732,19615732 0004,0007 HT HADHA USP49 19615732,19615732 0004,0007 HT CETN2 USP49 19615732,19615732 0004,0007 HT LRPPRC USP49 19615732,19615732 0004,0007 HT PPP5C USP49 19615732,19615732 0004,0007 HT COPA USP49 19615732,19615732 0004,0007 HT CETN1 USP49 19615732,19615732 0004,0007 HT FKBP5 USP49 19615732,19615732 0004,0007 HT KRR1 USP49 19615732,19615732 0004,0007 HT MCM6 USP49 19615732,19615732 0004,0007 HT SHPRH USP49 19615732,19615732 0004,0007 HT PDCD2 USP49 19615732,19615732 0004,0007 HT PPP6R3 USP49 19615732,19615732 0004,0007 HT USP49 HUWE1 19615732,19615732 0004,0007 HT USP49 ANKRD52 19615732,19615732 0004,0007 HT USP49 SHCBP1 19615732,19615732 0004,0007 HT USP49 SLC39A7 19615732,19615732 0004,0007 HT USP49 STAMBPL1 19615732,19615732 0004,0007 HT USP49 IPO9 19615732,19615732 0004,0007 HT USP49 NUP85 19615732,19615732 0004,0007 HT USP49 USP44 19615732,19615732 0004,0007 HT USP49 PPP6R1 19615732,19615732 0004,0007 HT USP49 DICER1 19615732,19615732 0004,0007 HT USP49 YARS2 19615732,19615732 0004,0007 HT USP49 HEL-S-94N 19615732 0004 HT B3KMJ7 USP49 19615732 0004 HT E9KL44 USP49 19615732 0004 HT ANKRD28 USP49 19615732,19615732 0004,0007 HT CETN3 USP49 19615732,19615732 0004,0007 HT PPM1G USP49 19615732,19615732 0004,0007 HT PPP6R2 USP49 19615732,19615732 0004,0007 HT UBR5 USP49 19615732,19615732 0004,0007 HT IPO7 USP49 19615732,19615732 0004,0007 HT RPN1 USP49 19615732,19615732 0004,0007 HT F7 USP49 19615732,19615732 0004,0007 HT PRKACA USP49 19615732,19615732 0004,0007 HT STIP1 USP49 19615732,19615732 0004,0007 HT HADHA USP49 19615732,19615732 0004,0007 HT CETN2 USP49 19615732,19615732 0004,0007 HT LRPPRC USP49 19615732,19615732 0004,0007 HT PPP5C USP49 19615732,19615732 0004,0007 HT COPA USP49 19615732,19615732 0004,0007 HT CETN1 USP49 19615732,19615732 0004,0007 HT FKBP5 USP49 19615732,19615732 0004,0007 HT KRR1 USP49 19615732,19615732 0004,0007 HT MCM6 USP49 19615732,19615732 0004,0007 HT SHPRH USP49 19615732,19615732 0004,0007 HT PDCD2 USP49 19615732,19615732 0004,0007 HT PPP6R3 USP49 19615732,19615732 0004,0007 HT USP49 HUWE1 19615732,19615732 0004,0007 HT USP49 ANKRD52 19615732,19615732 0004,0007 HT USP49 SHCBP1 19615732,19615732 0004,0007 HT USP49 SLC39A7 19615732,19615732 0004,0007 HT USP49 STAMBPL1 19615732,19615732 0004,0007 HT USP49 IPO9 19615732,19615732 0004,0007 HT USP49 NUP85 19615732,19615732 0004,0007 HT USP49 USP44 19615732,19615732 0004,0007 HT USP49 PPP6R1 19615732,19615732 0004,0007 HT USP49 DICER1 19615732,19615732 0004,0007 HT USP49 YARS2 19615732,19615732 0004,0007 HT USP49 HEL-S-94N 19615732 0004 HT B4DYC6 USP49 25036637 0729 HT FKBP6 USP49 25036637 0729 HT HSP90AA1 USP49 25036637 0729 HT HSP90AB1 USP49 25036637 0729 HT PPP5C USP49 25036637 0729 HT HSF2 USP49 25036637 0729 HT FKBP5 USP49 25036637 0729 HT PTGES3 USP49 25036637 0729 HT CDC37 USP49 25036637 0729 HT HIST2H2BE USP49 23824326 0415 LC USP49 NUDCD3 25036637 0729 HT USP49 Q96BE0 25036637 0729 HT USP49 AARSD1 25036637 0729 HT USP49 RBCK1 23105109 0018 LC USP49 Q9HAV2 25036637 0729 HT USP49 CACYBP 25036637 0729 HT USP49 STUB1 25036637 0729 HT USP49 TRIM35 23105109 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q70CQ1 B4DYC6 USP49 B4DYC6 0.126 25036637 Q8K2C9 Q70CQ1 PTPLAD1 USP49 0.126 25036637 Q9HAV2 Q70CQ1 Q9HAV2 USP49 0.126 25036637 Q70CQ1 O75344 USP49 FKBP6 0.126 25036637 Q70CQ1 Q6PK50 USP49 HSP90AB1 0.126 25036637 Q70CQ1 P07900 USP49 HSP90AA1 0.126 25036637 Q70CQ1 P62195 USP49 PSMC5 0.21 23824326 Q70CQ1 Q03933 USP49 HSF2 0.126 25036637 Q70CQ1 Q15185 USP49 PTGES3 0.126 25036637 Q70CQ1 Q16778 USP49 HIST2H2BE 0.309 23824326 Q8IVD9 Q70CQ1 NUDCD3 USP49 0.126 25036637 Q9BTE6 Q70CQ1 AARSD1 USP49 0.126 25036637 Q9BYM8 Q70CQ1 RBCK1 USP49 0.183 23105109 Q9HB71 Q70CQ1 CACYBP USP49 0.126 25036637 Q9UPQ4 Q70CQ1 TRIM35 USP49 0.183 23105109 Q9Y265 Q70CQ1 RUVBL1 USP49 0.21 23824326 Q96FJ0 Q70CQ1 STAMBPL1 USP49 0.236 19615732 Q9BW27 Q70CQ1 NUP85 USP49 0.236 19615732 Q70CQ1 P53041 USP49 PPP5C 0.236 19615732 Q70CQ1 P04843 USP49 RPN1 0.236 19615732 Q70CQ1 O15355 USP49 PPM1G 0.236 19615732 Q70CQ1 O15084 USP49 ANKRD28 0.236 19615732 Q70CQ1 O15182 USP49 CETN3 0.236 19615732 Q70CQ1 O95373 USP49 IPO7 0.236 19615732 Q70CQ1 O75170 USP49 PPP6R2 0.236 19615732 Q70CQ1 O95071 USP49 UBR5 0.236 19615732 Q70CQ1 P43490 USP49 NAMPT 0.236 unassigned1304 Q70CQ1 P31948 USP49 STIP1 0.236 19615732 Q70CQ1 P08709 USP49 F7 0.236 19615732 Q70CQ1 P17612 USP49 PRKACA 0.236 19615732 Q70CQ1 P42704 USP49 LRPPRC 0.236 19615732 Q70CQ1 P40939 USP49 HADHA 0.236 19615732 Q70CQ1 P41208 USP49 CETN2 0.236 19615732 Q96P70 Q70CQ1 IPO9 USP49 0.236 19615732 Q70CQ1 Q14566 USP49 MCM6 0.236 19615732 Q70CQ1 P53621 USP49 COPA 0.236 19615732 Q70CQ1 Q13601 USP49 KRR1 0.236 19615732 Q70CQ1 Q12798 USP49 CETN1 0.236 19615732 Q92504 Q70CQ1 SLC39A7 USP49 0.236 19615732 Q70CQ1 Q5H9R7 USP49 PPP6R3 0.236 19615732 Q70CQ1 Q149N8 USP49 SHPRH 0.236 19615732 Q70CQ1 Q16342 USP49 PDCD2 0.236 19615732 Q8NEM2 Q70CQ1 SHCBP1 USP49 0.236 19615732 Q7Z6Z7 Q70CQ1 HUWE1 USP49 0.236 19615732 Q8NB46 Q70CQ1 ANKRD52 USP49 0.236 19615732 Q9UPN7 Q70CQ1 PPP6R1 USP49 0.236 19615732 Q9H0E7 Q70CQ1 USP44 USP49 0.236 19615732 Q9UPY3 Q70CQ1 DICER1 USP49 0.236 19615732 Q9Y2Z4 Q70CQ1 YARS2 USP49 0.236 19615732 Q96BE0 Q70CQ1 Q96BE0 USP49 0.126 25036637 Q9BPW0 Q70CQ1 PPP5C USP49 0.126 25036637 Q9UNE7 Q70CQ1 STUB1 USP49 0.126 25036637 Q70CQ1 Q13451 USP49 FKBP5 0.332 25036637,19615732 Q70CQ1 Q16543 USP49 CDC37 0.126 25036637

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 ANKRD28 USP49 MI:0045 experimental interaction detection MI:0461 interaction database CETN3 USP49 MI:0045 experimental interaction detection MI:0461 interaction database PPM1G USP49 MI:0045 experimental interaction detection MI:0461 interaction database PPP6R2 USP49 MI:0045 experimental interaction detection MI:0461 interaction database FKBP6 USP49 MI:0045 experimental interaction detection MI:0461 interaction database UBR5 USP49 MI:0045 experimental interaction detection MI:0461 interaction database IPO7 USP49 MI:0045 experimental interaction detection MI:0461 interaction database RPN1 USP49 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AA1 USP49 MI:0045 experimental interaction detection MI:0461 interaction database F7 USP49 MI:0045 experimental interaction detection MI:0461 interaction database UBB USP49 MI:0362 inference MI:1106 pathways database UBC USP49 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database PRKACA USP49 MI:0045 experimental interaction detection MI:0461 interaction database STIP1 USP49 MI:0045 experimental interaction detection MI:0461 interaction database HADHA USP49 MI:0045 experimental interaction detection MI:0461 interaction database CETN2 USP49 MI:0045 experimental interaction detection MI:0461 interaction database LRPPRC USP49 MI:0045 experimental interaction detection MI:0461 interaction database PPP5C USP49 MI:0045 experimental interaction detection MI:0461 interaction database COPA USP49 MI:0045 experimental interaction detection MI:0461 interaction database SUMO3 USP49 MI:0045 experimental interaction detection MI:0461 interaction database PSMC5 USP49 MI:0045 experimental interaction detection MI:0461 interaction database RPS27A USP49 MI:0362 inference MI:1106 pathways database UBA52 USP49 MI:0362 inference MI:1106 pathways database HSF2 USP49 MI:0045 experimental interaction detection MI:0461 interaction database CETN1 USP49 MI:0045 experimental interaction detection MI:0461 interaction database FKBP5 USP49 MI:0045 experimental interaction detection MI:0461 interaction database KRR1 USP49 MI:0045 experimental interaction detection MI:0461 interaction database MCM6 USP49 MI:0045 experimental interaction detection MI:0461 interaction database SHPRH USP49 MI:0045 experimental interaction detection MI:0461 interaction database PTGES3 USP49 MI:0045 experimental interaction detection MI:0461 interaction database PDCD2 USP49 MI:0045 experimental interaction detection MI:0461 interaction database CDC37 USP49 MI:0045 experimental interaction detection MI:0461 interaction database HIST2H2BE USP49 MI:0045 experimental interaction detection MI:0461 interaction database PPP6R3 USP49 MI:0045 experimental interaction detection MI:0461 interaction database HACD4 USP49 MI:0362 inference MI:0461 interaction database USP49 HUWE1 MI:0045 experimental interaction detection MI:0461 interaction database USP49 NUDCD3 MI:0045 experimental interaction detection MI:0461 interaction database USP49 ANKRD52 MI:0045 experimental interaction detection MI:0461 interaction database USP49 SHCBP1 MI:0045 experimental interaction detection MI:0461 interaction database USP49 SLC39A7 MI:0045 experimental interaction detection MI:0461 interaction database USP49 STAMBPL1 MI:0045 experimental interaction detection MI:0461 interaction database USP49 IPO9 MI:0045 experimental interaction detection MI:0461 interaction database USP49 AARSD1 MI:0045 experimental interaction detection MI:0461 interaction database USP49 NUP85 MI:0045 experimental interaction detection MI:0461 interaction database USP49 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database USP49 USP44 MI:0045 experimental interaction detection MI:0461 interaction database USP49 CACYBP MI:0045 experimental interaction detection MI:0461 interaction database USP49 HACD3 MI:0362 inference MI:0461 interaction database USP49 STUB1 MI:0045 experimental interaction detection MI:0461 interaction database USP49 PPP6R1 MI:0045 experimental interaction detection MI:0461 interaction database USP49 TRIM35 MI:0045 experimental interaction detection MI:0461 interaction database USP49 DICER1 MI:0045 experimental interaction detection MI:0461 interaction database USP49 RUVBL1 MI:0045 experimental interaction detection MI:0461 interaction database USP49 YARS2 MI:0045 experimental interaction detection MI:0461 interaction database