PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus KLHL26 KLHL14 26186194 biogrid exp P P P P P P GP P P GP P P P P P P P P P P P MYZAP KLHL26 26186194 biogrid exp P P P P P P P P P P P P P P P KLHL26 NUDCD2 25036637 intact exp GP P G GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G CUL3 KLHL26 21145461 innatedb,biogrid exp GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G KLHL26 CD209 26186194 biogrid exp G G P G G G G G P GP G G G G G G G G G G G G KLHL26 COPS5 21145461 biogrid exp GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G SPINT2 KLHL26 26186194 biogrid exp GP P G P GP G GP G GP P P GP G GP GP P GP G P GP GP P GP GP GP G CSPP1 KLHL26 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G HSP90AB1 KLHL26 22939624 intact exp GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G KLHL26 TXNDC5 26186194 biogrid exp P P P P P P P P KLHL26 ACIN1 16169070 hprd,i2d,mint,intact exp GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G HSP90AA1 KLHL26 22939624 biogrid exp GP P G GP G GP G G G G G GP G G P G G G G G GP G KLHL26 DCUN1D1 21145461 biogrid exp P G GP G P P G P P P P GP GP G P GP P GP GP P GP G KLHL26 KLHL20 26186194 biogrid exp GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G KLHL26 UBQLN4 16713569 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G PCMT1 KLHL26 26186194 biogrid exp GP P G P GP G P G G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G KLHL26 NUDCD3 25036637 intact exp GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G KLHL26 MBIP 26186194 biogrid exp GP P G P GP G P G G GP P GP G GP GP GP G P GP G G GP GP GP G KLHL26 NUDC 25036637 intact exp GP P G P GP G GP G GP P P GP G GP GP P GP G P GP GP G GP GP GP G KLHL26 KLHL1 23023127 pred P G P G P P G P P P P P KLHL26 BTBD10 23023127 pred GP P G P GP G P GP G GP P GP G G GP GP G P GP GP G G G GP G KLHL26 KLHL15 23023127 pred GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G KLHL26 FBXW7 23023127 pred GP P G P GP G P GP G GP P P GP G GP GP GP G P GP GP GP GP GP GP KLHL26 BTRC 23023127 pred GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G SOCS3 KLHL26 23023127 pred GP P G P GP G P GP G GP P P G G GP GP P GP G P G GP GP GP GP GP G KLHL12 KLHL26 23023127 pred G G G G G G G G G G G G G G G G G G G G KLHL26 BTBD6 23023127 pred G G P G G GP G G GP G GP G G G G G GP GP G G G KLHL26 UNC5D 23023127 pred P P G P GP P P G GP P P GP GP P P G P GP P P P P KLHL2 KLHL26 23023127 pred G G G G G G GP P G G GP G G G GP G G GP G GP G KLHL26 KLHL3 23023127 pred G P G GP G P GP G GP P P G G GP GP GP G P G GP GP GP GP GP G KLHL26 BTBD1 23023127 pred GP P G P GP G P GP G GP P P GP G GP GP G G P GP GP GP GP GP GP G KBTBD11 KLHL26 23023127 pred GP P G P GP G P GP G GP P P GP G GP GP P P G P GP P GP GP P P G KLHL18 KLHL26 23023127 pred G P G P GP G P GP G GP P P G G GP GP GP G GP GP GP GP GP G SOCS5 KLHL26 23023127 pred GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G KLHL26 ZBTB9 23023127 pred GP P G P GP G P GP G GP P G G GP GP P GP G P GP GP G GP GP GP G BCL6 KLHL26 23023127 pred G G P G G G G G GP G G G G G P G G G G G G G KLHL26 BTBD9 23023127 pred P G P GP G GP G G P GP G G GP GP G G GP G G GP GP G KCNA2 KLHL26 23023127 pred G G GP G P G P P P P G GP GP P P G P P P G P GP P KLHL26 BTBD2 23023127 pred G G G G G G G G G G G G G G G G G G G ENC1 KLHL26 23023127 pred GP P G GP G P GP G GP P GP G GP GP GP G P GP GP G GP GP GP G KLHL26 ZBTB44 23023127 pred GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G KLHL38 KLHL26 23023127 pred P P P P P P P P P P P P P P P P P P P P ZBTB7B KLHL26 23023127 pred GP P P P GP G G GP G GP P G P GP GP G GP GP P KLHL26 KLHL4 23023127 pred P P G P GP P G P P P G P GP P P P P P KLHL26 FBXL2 23023127 pred G G G G G G G G G G G G G G G G KBTBD12 KLHL26 23023127 pred P P G GP G P P G P P P GP GP P G P GP GP GP GP P KLHL26 GMCL1 23023127 pred GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP GP GP GP GP G KCNA1 KLHL26 23023127 pred GP P G P GP G P GP G P P P P G GP GP P GP G P P GP GP GP GP GP G KLHL26 BTBD3 23023127 pred GP P G P GP G P GP G GP P P GP G GP GP P GP G P GP GP G GP GP GP G KLHL26 KLHL11 23023127 pred P P P P P P P P P P P P P P P P GP

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBC KLHL26 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21906983,21963094,21987572,22505724 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_171689|BIOGRID_224535|BIOGRID_163598|BIOGRID_180858|BIOGRID_264342 bait|bait|bait|bait|bait prey|prey|prey|prey|prey KLHL26 DCUN1D1 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_205994 prey bait CUL3 KLHL26 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_201886 bait prey NRF1 KLHL26 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_296385 bait prey HSP90AB1 KLHL26 MI:0729(luminescence based mammalian interactome mapping) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_125038 prey bait KLHL26 COPS5 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_205316 prey bait HSP90AA1 KLHL26 MI:0004(affinity chromatography technology) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_255395 bait prey KLHL26 UBQLN4 MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down) 16713569 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|(intact)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint) BIOGRID_215179|UniProt_85669|MINT_50759|HPRD_34844|MINT_83047 prey|bait|prey|-|prey bait|prey|bait|-|bait KLHL26 ACIN1 MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|MI:0471(mint)|MI:0471(mint)|(intact) HPRD_29409|MINT_65375|MINT_36259|UniProt_156862 -|bait|bait|bait -|prey|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality SPINT2 KLHL26 26186194 0004 HT POLR2M KLHL26 26186194 0004 HT PCMT1 KLHL26 26186194 0004 HT CUL3 KLHL26 21145461 0004 HT KLHL26 TXNDC5 26186194 0004 HT KLHL26 COPS5 21145461 0004 HT KLHL26 DCUN1D1 21145461 0004 HT KLHL26 Q9H688 26186194 0004 HT KLHL26 CD209 26186194 0004 HT KLHL26 MBIP 26186194 0004 HT KLHL26 KLHL14 26186194 0004 HT KLHL26 KLHL20 26186194 0004 HT SPINT2 KLHL26 26186194 0004 HT POLR2M KLHL26 26186194 0004 HT PCMT1 KLHL26 26186194 0004 HT CUL3 KLHL26 21145461 0004 HT KLHL26 TXNDC5 26186194 0004 HT KLHL26 COPS5 21145461 0004 HT KLHL26 DCUN1D1 21145461 0004 HT KLHL26 Q9H688 26186194 0004 HT KLHL26 CD209 26186194 0004 HT KLHL26 MBIP 26186194 0004 HT KLHL26 KLHL14 26186194 0004 HT KLHL26 KLHL20 26186194 0004 HT HSP90AB1 KLHL26 22939624 0729 HT KLHL26 NUDCD3 25036637 0729 HT KLHL26 NUDCD2 25036637 0729 HT KLHL26 UBQLN4 16713569,16713569 0397,0018 HT KLHL26 ACIN1 16169070,16169070 0018,0398 HT KLHL26 NUDC 25036637 0729 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q53HC5 P08238 KLHL26 HSP90AB1 0.126 22939624 Q8WVJ2 Q53HC5 NUDCD2 KLHL26 0.126 25036637 Q53HC5 O43291 KLHL26 SPINT2 0.126 26186194 Q53HC5 Q1MSJ5 KLHL26 CSPP1 0.126 26186194 Q8NBS9 Q53HC5 TXNDC5 KLHL26 0.126 26186194 Q9NNX6 Q53HC5 CD209 KLHL26 0.126 26186194 Q9NS73 Q53HC5 MBIP KLHL26 0.126 26186194 Q8IVD9 Q53HC5 NUDCD3 KLHL26 0.126 25036637 Q53HC5 P07900 KLHL26 HSP90AA1 0.126 22939624 Q9Y2M5 Q53HC5 KLHL20 KLHL26 0.126 26186194 Q9Y266 Q53HC5 NUDC KLHL26 0.126 25036637 Q53HC5 P0CAP1 KLHL26 MYZAP 0.126 26186194 Q53HC5 P0CAP2 KLHL26 POLR2M 0.126 26186194 Q6EEV4 Q53HC5 POLR2M KLHL26 0.126 26186194 Q9NRR5 Q53HC5 UBQLN4 KLHL26 0.286 16713569 Q53HC5 P0CG20 KLHL26 PRR35 0.236 unassigned1304 Q9BRQ3 Q53HC5 NUDT22 KLHL26 0.236 unassigned1304 Q9H0I2 Q53HC5 ENKD1 KLHL26 0.236 unassigned1304 Q53HC5 Q15915 KLHL26 ZIC1 0.236 unassigned1304 Q53HC5 P78337 KLHL26 PITX1 0.236 unassigned1304 Q53HC5 Q49AR9 KLHL26 ANKS1A {ECO:0000313|EMBL:AAH31934.1} 0.236 unassigned1304 Q53HC5 Q0VD86 KLHL26 INCA1 0.236 unassigned1304 Q53HC5 P29972 KLHL26 AQP1 0.236 unassigned1304 Q7L273 Q53HC5 KCTD9 KLHL26 0.236 unassigned1304 Q53HC5 P32242 KLHL26 OTX1 0.236 unassigned1304 Q7Z3K3 Q53HC5 POGZ KLHL26 0.236 unassigned1304 Q53HC5 O75593 KLHL26 FOXH1 0.236 unassigned1304 Q92905 Q53HC5 COPS5 KLHL26 0.126 21145461 Q96GG9 Q53HC5 DCUN1D1 KLHL26 0.126 21145461 Q9P2G3 Q53HC5 KLHL14 KLHL26 0.126 26186194 Q9UKV3 Q53HC5 ACIN1 KLHL26 0.126 16169070 Q53HC5 Q13618 KLHL26 CUL3 0.126 21145461 Q53HC5 P22061 KLHL26 PCMT1 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SPINT2 KLHL26 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AA1 KLHL26 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AB1 KLHL26 MI:0045 experimental interaction detection MI:0461 interaction database MYZAP KLHL26 MI:0045 experimental interaction detection MI:0461 interaction database POLR2M KLHL26 MI:0045 experimental interaction detection MI:0461 interaction database UBC KLHL26 MI:0045 experimental interaction detection MI:0461 interaction database ATF2 KLHL26 MI:0045 experimental interaction detection MI:0461 interaction database PCMT1 KLHL26 MI:0045 experimental interaction detection MI:0461 interaction database CUL3 KLHL26 MI:0045 experimental interaction detection MI:0461 interaction database CSPP1 KLHL26 MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 POLR2M MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 NUDCD3 MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 TXNDC5 MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 NUDCD2 MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 COPS5 MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 DCUN1D1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 CD209 MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 UBQLN4 MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 MBIP MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 KLHL14 MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 ACIN1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 NUDC MI:0045 experimental interaction detection MI:0461 interaction database KLHL26 KLHL20 MI:0045 experimental interaction detection MI:0461 interaction database