PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus WDR81 NXF1 22658674 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PPP4C WDR81 19156129 biogrid exp GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G WDR81 NUDC 25036637 intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G XPO1 WDR81 26673895 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G WDR81 MOV10 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G CUL3 WDR81 21145461 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G WDR81 TMEM237 26638075 biogrid,intact exp GP GP G G G GP G GP GP G GP GP G G GP GP G GP G GP GP GP G GP GP GP G WDR81 BLNK 21822214 biogrid exp GP P G G GP GP G P GP G GP G G GP G GP GP GP GP G GP G G GP GP GP P G WDR81 MAPK15 23602568 biogrid,intact exp GP GP G G G GP GP GP G GP G GP P GP GP P GP G GP P GP GP GP GP GP G NTRK1 WDR81 25921289 biogrid exp P P P G P P P P P P P P P P P P P P SHMT2 WDR81 22658674 biogrid exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ENO1 WDR81 22658674 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PPP1CA WDR81 19389623 intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q562E7 tandem affinity purification 23602568 association C 8 P62136 Q562E7 pull down 19389623 direct interaction X 2 Q562E7 Q9Y266 luminescence based mammalian interactome mapping 25036637 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B WDR81 BLNK MI:0004(affinity chromatography technology) 21822214 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191081 prey bait PPP4C WDR81 MI:0004(affinity chromatography technology) 19156129 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_144679 bait prey CUL3 WDR81 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_202126 bait prey PPP1CA WDR81 MI:0047(far western blotting) 19389623 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (intact) UniProt_98444 bait prey UBC WDR81 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 21906983,21963094,21987572,22505724 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_264136|BIOGRID_267271|BIOGRID_163984|BIOGRID_178769 bait|bait|bait|bait prey|prey|prey|prey WDR81 MAPK15 MI:0676(tandem affinity purification)|MI:0004(affinity chromatography technology) 23602568 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_128785|BIOGRID_291107 prey|prey bait|bait

PPI - HINT Gene A Gene B PMID Method Quality CUL3 WDR81 21145461 0004 HT WDR81 MAPK15 23602568,23602568 0004,0676 HT WDR81 TMEM237 26638075,26638075 1314,1313 HT CUL3 WDR81 21145461 0004 HT WDR81 MAPK15 23602568,23602568 0004,0676 HT WDR81 TMEM237 26638075,26638075 1314,1313 HT WDR81 NUDC 25036637 0729 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9Y266 Q562E7 NUDC WDR81 0.126 25036637 Q562E7 P60510 WDR81 PPP4C 0.126 19156129 Q562E7 P61006 WDR81 RAB8A 0.126 26824392 Q562E7 P62139 WDR81 PPP1CA 0.126 19389623 Q9HCE1 Q562E7 MOV10 WDR81 0.126 22658674 Q6P5F9 Q562E7 XPO1 WDR81 0.126 26673895 Q562E7 P04629 WDR81 NTRK1 0.126 25921289 Q562E7 P06733 WDR81 ENO1 0.126 22658674 Q8TD08 Q562E7 MAPK15 WDR81 0.236 23602568 Q8WV28 Q562E7 BLNK WDR81 0.21 21822214 Q96Q45 Q562E7 TMEM237 WDR81 0.126 26638075 Q9UBU9 Q562E7 NXF1 WDR81 0.126 22658674 Q562E7 P34897 WDR81 SHMT2 0.126 22658674 Q562E7 Q13618 WDR81 CUL3 0.126 21145461