PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBE2V2 SUV39H2 16169070 hprd,i2d,mint,intact exp G G G G G G G G G G G G G G UBE2V2 USP34 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TTLL12 UBE2V2 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM23 UBE2V2 20724660 innatedb exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MKRN3 UBE2V2 19549727 biogrid,intact exp ZPR1 UBE2V2 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RPS21 UBE2V2 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SEC23A UBE2V2 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CD2BP2 UBE2V2 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 MOB4 16169070 hprd,biogrid,i2d,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SSSCA1 UBE2V2 22939629 biogrid exp G G G G G G G G G G G G G G G G RHOA UBE2V2 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 SIAH1 19549727 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 TTC9C 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RIF1 16169070 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 ZYX 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ZRANB2 UBE2V2 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RNF2 19549727 biogrid,intact exp G VPS26A UBE2V2 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 LRIF1 16169070 hprd,biogrid,i2d,mint exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 TIGD6 26496610 biogrid,intact exp UBA1 UBE2V2 20724660 innatedb exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G EGFR UBE2V2 20029029 biogrid,i2d,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF144A UBE2V2 19549727 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 POLK 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SNTA1 UBE2V2 19549727 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 USP9X 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 TRIM5 19549727 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G UBC UBE2V2 12834344,11504715,12569095,16518696 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CPLX1 UBE2V2 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G UBE2V2 IGSF21 16169070 hprd,biogrid,i2d,mint,intact exp G G G G G G ATP6V1B2 UBE2V2 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 OTUB1 22679021 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 ZFYVE19 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G EIF1B UBE2V2 17353931 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 MALSU1 19549727 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2N UBE2V2 16129784,19549727,22939629,11473244,11504715,12569095,25909880,15147900,24145445,16215985,18678647,15749714,16122702,16112642,26344197,12847084,17964296,18316726,12834344,14517261,21114314,11473255, 25402006, 23023127, 21836163, 16082366 innatedb,hprd,biogrid,i2d,intact,bci exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP14 UBE2V2 19549727, 23023127 intact exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 STUB1 22939629, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BCL10 UBE2V2 14695475, 25402006 innatedb,hprd,biogrid,i2d,bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SHPRH UBE2V2 17108083, 21836163 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF2 UBE2V2 20047764, 25402006 biogrid exp, pred G G UBXN1 UBE2V2 22939629, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 MALT1 14695475, 25402006 innatedb,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 HUWE1 23023127 bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HLTF UBE2V2 18316726,22904075, 25402006 biogrid,dip exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 ZNRF1 19549727, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RNF11 23751493, 25402006, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 DZIP3 19549727, 23023127 biogrid,intact,bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V1 UBE2V2 22939629, 25402006, 23023127 biogrid exp, pred UBE2M UBE2V2 26344197, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 TRAF6 17353931, 25402006, 23023127 intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2B UBE2V2 22939629, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN7 UBE2V2 22939629, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3C UBE2V2 16082366 bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2L3 UBE2V2 22939629, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 UBE2V2 22589545, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G XIAP UBE2V2 19549727, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UFM1 UBE2V2 22939629, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RAD23B UBE2V2 22939629, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM32 UBE2V2 21143188, 25402006 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 FBXO32 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 UBE2V2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 BIN3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 TRPM7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G OTC UBE2V2 ortho G G G UBE2V2 RPGRIP1L ortho G G G G DLG4 UBE2V2 25402006 ortho, pred G G G G G G G G G G G G G G G UBE2G2 UBE2V2 25402006, 23023127 ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 NEDD4L 16082366 ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G TMEM189 UBE2V2 25402006 pred UBE2V2 SLX1A, SLX1B 23023127 pred PIN1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBXN11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 HECTD1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HERC2 UBE2V2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 PIR51 25402006 pred G G G G G G G UBE2V2 UBQLN1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2R2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 NFATC2IP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 POLH 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 NSFL1C 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 DDI2 23023127 pred UBE2V2 MAP1LC3B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN2A UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2NL 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 16082366 pred UBE2V2 LRSAM1 25402006 pred G G G G G G G G G G G G G G G G UBOX5 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 SUMO4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RPS27A UBE2V2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2E1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUMO1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 HECW1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 DTX3L 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 PFDN2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CCNH UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 C9orf89 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 CARD14 25402006 pred G G G G G G G G G G G G G G G G G G BIRC2 UBE2V2 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AP2A2 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 ITCH 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ERCC8 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ARAF UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2F 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RNF5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DCLK1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G UBR5 UBE2V2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDK5 UBE2V2 23023127 pred G G G G G G G G G G G G UBC UBE2V2 23023127 pred BRCC3 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G PAK1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UCHL1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RBX1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SQSTM1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAP2K4 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 TRAF7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 AKTIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NCF2 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G UBE2V2 UBXN10 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 NFE2 21836163 pred G G G UBE2V2 TMUB2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBQLNL 23023127 pred G G UBE2V2 HERPUD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RCHY1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAP3K1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GTF2H1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBL7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 BIRC7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G GTF2H2 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 NHLRC1 23023127 pred UBE2V2 RNF41 23023127 pred G G G G G G G G G G G G G G G G G G G G G RAF1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBFD1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBTD1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G POLR2K UBE2V2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DFFB UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G RPA2 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 HECW2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G BCL3 UBE2V2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G BRCA1 UBE2V2 23023127, 16082366 pred G G G G UBE2V2 UBQLN3 16082366 pred G G G G G G G G UBE2V2 MAP3K2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 ANAPC2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DBT UBE2V2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2U 23023127 pred G UBE2V2 XRN2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2K UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 ATG5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 SMARCAD1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 HECTD3 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CHAF1B UBE2V2 23023127 pred G G G UBE2V2 FAF1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2S 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G PRKCI UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DFFA UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBLCP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RAD54L 25402006 pred G G G G G G G UBE2V2 EPB41L4B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G AP2B1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2J2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 MIDN 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 CHFR 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RNF168 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CNOT4 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2Q2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2D4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2A UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RNF167 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PRKCG UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G UBE2V2 CARD10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 ARMC1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2D3 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 MAP3K3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 SMURF2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AREL1 UBE2V2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM21 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RNF19A 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBL4A UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBL4B 23023127 pred UBE2L6 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2D2 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BAG6 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BIRC3 UBE2V2 25402006 pred G G G G G G G G G G G G G G G G G G G UBE2V2 ISG20 23023127 pred G G G G G G G G G G G G G G G G G G G G G RNF4 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 HACE1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AXIN1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G PARK2 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G RNF103 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2Q1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UHRF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2D1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 MYO7B 23023127 pred G G G G G G G G G G G G G G G UBE2V2 COPS5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2C UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 WWP1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HERC3 UBE2V2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 HESX1 21836163 pred UBE2V2 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2T 23023127 pred G G G G G G G G G G G G G UBXN8 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RNF135 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 MTUS1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN2B UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CIDEA UBE2V2 23023127 pred G G G G G G G G UBE2V2 UBE2W 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBA3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DVL2 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RPA1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAPK8IP2 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 SMURF1 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAP3K7 UBE2V2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 TMUB1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RBBP6 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HRAS UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RNF14 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 MAP1LC3A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 TAB2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE2E2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBB UBE2V2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBL5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RFPL4B 23023127 pred UBE2V2 GABARAPL3 23023127 pred UBE2V2 CARD9 25402006 pred G G G G UBE2V2 ATG3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUMO2 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 DVL3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NBR1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUMO3 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TP53 UBE2V2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BRD4 UBE2V2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HERPUD1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 UBE3B 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 CARD11 25402006 pred G G G G G CDC34 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2H UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAFK UBE2V2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 HECTD2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 UBE2V2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 GABARAPL1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 PRPF19 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDK7 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G RGS14 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE4A UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAPK3 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SF3A1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HERC1 UBE2V2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PIK3CA UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G PSMD12 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G COPS2 UBE2V2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2G1 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIP12 UBE2V2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 HERC6 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G AURKA UBE2V2 25402006, 21836163 pred G G G G G G G G G G G G G G RAD23A UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RNF25 23023127 pred G G UBE2V2 UBQLN2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 DDI1 23023127 pred G G G G G MAPK9 UBE2V2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 AMFR 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 HERC5 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RFC2 UBE2V2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 NEDD8 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V2 RNF175 23023127 pred G G G G G G G G G G G G G G G G G UBE2V2 RAD18 23023127 pred G G G UBE2V2 UBTD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NEDD4 UBE2V2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G UBE2I UBE2V2 23023127, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBXN1 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236567 prey bait ATP6V1B2 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236594 prey bait UBE2V2 TRIM5 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124566|UniProt_101417 bait|bait prey|prey SNTA1 UBE2V2 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100876 prey bait ZNF259 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240270 prey bait UBE2V2 STUB1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238608 prey bait UBE2V2 ZNRF1 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124332|UniProt_101415 bait|bait prey|prey UBE2V2 RNF2 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101411|BIOGRID_124506 bait|bait prey|prey UBE2V2 TTC9C MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_241920 prey bait UBE2V2 ZYX MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236544 bait prey SHPRH UBE2V2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17108083 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194182|BIOGRID_225679 bait|bait prey|prey UBE2N UBE2V2 MI:0007(anti tag coimmunoprecipitation)|MI:0114(x-ray crystallography)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0114(x-ray crystallography)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0114(x-ray crystallography)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0114(x-ray crystallography)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0114(x-ray crystallography)|MI:0018(two hybrid)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0401(biochemical)|MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo) 11473244,11473255,12569095,12834344,12847084,14517261,15147900,15749714,16112642,16122702,16129784,16215985,18316726,18678647,19549727,21114314,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization)|-|-|- MI:0465(dip)|(biogrid)|(intact)|(biogrid)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|MI:0465(dip)|MI:0468(hprd) DIP_53940|BIOGRID_196873|UniProt_100877|BIOGRID_192336|UniProt_68223|BIOGRID_208298|BIOGRID_192334|UniProt_100870|BIOGRID_148387|BIOGRID_207945|BIOGRID_196319|BIOGRID_207946|BIOGRID_126474|BIOGRID_197180|BIOGRID_208290|BIOGRID_126471|BIOGRID_207743|BIOGRID_207947|BIOGRID_258636|BIOGRID_194170|BIOGRID_226007|BIOGRID_197340|BIOGRID_230831|HPRD_11871|DIP_53941|HPRD_40063 -|prey|prey|prey|neutral component|bait|bait|bait|prey|bait|prey|bait|prey|prey|bait|prey|prey|prey|prey|bait|bait|prey|prey|-|-|- -|bait|bait|bait|neutral component|prey|prey|prey|bait|prey|bait|prey|bait|bait|prey|bait|bait|bait|bait|prey|prey|bait|bait|-|-|- MKRN3 UBE2V2 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124429|UniProt_101412 prey|prey bait|bait RAD23B UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_235838 bait prey UBE2V2 MALSU1 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100879 bait prey UBXN7 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236667 prey bait XIAP UBE2V2 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101408|BIOGRID_124235 prey|prey bait|bait UBE2V2 ZFYVE19 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240265 bait prey UBE2V2 IGSF21 MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association) (intact)|MI:0471(mint)|(biogrid)|MI:0468(hprd)|MI:0471(mint) UniProt_155004|MINT_63416|BIOGRID_95472|HPRD_22138|MINT_34460 bait|bait|bait|-|bait prey|prey|prey|-|prey UBE2V2 OTUB1 MI:0096(pull down) 22679021 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_196276 prey bait UBE2V2 RIF1 MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_155859 bait prey VPS26A UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238215 prey bait RPS21 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_241895 bait prey BCL10 UBE2V2 MI:0493(in vivo) 14695475 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_17370 - - SSSCA1 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236907 bait prey UBE2B UBE2V2 MI:0401(biochemical)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo) 18316726,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|-|- (biogrid)|MI:0465(dip)|MI:0468(hprd) BIOGRID_235699|DIP_53941|HPRD_40063 prey|-|- bait|-|- UBE2V2 SUV39H2 MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(intact) HPRD_29203|UniProt_157198 -|prey -|bait UBE2V1 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236350 bait prey TRIM32 UBE2V2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_194248|BIOGRID_194354|BIOGRID_194254 bait|bait|prey prey|prey|bait CPLX1 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239689 bait prey RNF8 UBE2V2 MI:0096(pull down) 22589545 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_188053 bait prey TRAF2 UBE2V2 MI:0018(two hybrid) 20047764 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226107 bait prey RNF144A UBE2V2 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101413|BIOGRID_124491 prey|prey bait|bait UBE2V2 SIAH1 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101410|BIOGRID_124362 bait|bait prey|prey USP14 UBE2V2 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100878 prey bait UBE2V2 USP34 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236666 bait prey UBE2V2 RNF11 MI:0004(affinity chromatography technology) 23751493 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_282487 prey bait UBE2V2 MOB4 MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|(intact)|MI:0471(mint)|MI:0471(mint)|(biogrid) HPRD_29204|UniProt_155624|MINT_36452|MINT_65568|BIOGRID_94685 -|prey|prey|prey|prey -|bait|bait|bait|bait UBE2V2 TRAF6 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_150419 prey bait ZRANB2 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240271 prey bait UBE2V2 DZIP3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124393|UniProt_101414 bait|bait prey|prey UBE2V2 SUV39H2 MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_34588|MINT_63544 prey|prey bait|bait HLTF UBE2V2 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 18316726 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|- MI:0465(dip)|MI:0465(dip)|(biogrid)|MI:0465(dip)|(biogrid)|MI:0468(hprd) DIP_53940|DIP_53941|BIOGRID_117295|DIP_54049|BIOGRID_117293|HPRD_40063 -|-|bait|-|bait|- -|-|prey|-|prey|- UFM1 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240949 prey bait TTLL12 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_237084 bait prey EIF1B UBE2V2 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_145780 bait prey CD2BP2 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_241231 bait prey UBE2L3 UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238900 bait prey SEC23A UBE2V2 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239444 bait prey UBE2V2 LRIF1 MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|MI:0471(mint)|MI:0471(mint) HPRD_29205|BIOGRID_94915|MINT_63417|MINT_34461 -|bait|bait|bait -|prey|prey|prey EGFR UBE2V2 MI:0090(protein complementation assay)|MI:0112(ubiquitin reconstruction) 20029029 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123291|UniProt_103198 bait|bait prey|prey UBC UBE2V2 MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography) 12569095,12834344,16518696,17218787,21139048,21890473,21906983,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_179297|BIOGRID_196872|BIOGRID_170027|BIOGRID_269836|BIOGRID_141380|BIOGRID_197178|BIOGRID_196868|BIOGRID_172835|BIOGRID_225044|BIOGRID_205028 bait|prey|bait|bait|prey|prey|prey|bait|bait|prey prey|bait|prey|prey|bait|bait|bait|prey|prey|bait UBE2V2 USP9X MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236602 bait prey

PPI - HINT Gene A Gene B PMID Method Quality CPLX1 UBE2V2 22939629 0401 HT SSSCA1 UBE2V2 22939629 0401 HT EIF1B UBE2V2 17353931 0006 HT ZPR1 UBE2V2 22939629 0401 HT VPS26A UBE2V2 22939629 0401 HT UBXN7 UBE2V2 22939629 0401 HT ZRANB2 UBE2V2 22939629 0401 HT CD2BP2 UBE2V2 22939629 0401 HT UBC UBE2V2 11504715,12834344,12834344 0096,0114,0096 LC ATP6V1B2 UBE2V2 22939629 0401 HT RAD23B UBE2V2 22939629 0401 HT UBE2M UBE2V2 26344197 0401 HT UBE2N UBE2V2 14517261,16129784,16122702,12834344,16129784,27173435 0096,0096,0004,0096,0018,0676 LC,HT RHOA UBE2V2 26496610 0007 HT UFM1 UBE2V2 22939629 0401 HT UBE2B UBE2V2 22939629 0401 HT RPS21 UBE2V2 22939629 0401 HT UBE2L3 UBE2V2 22939629 0401 HT UBXN1 UBE2V2 22939629 0401 HT UBE2V1 UBE2V2 22939629 0401 HT TTLL12 UBE2V2 22939629 0401 HT HLTF UBE2V2 18316726,18316726,18316726,22904075 0004,0007,0096,0096 LC SEC23A UBE2V2 22939629 0401 HT UBE2V2 ZYX 22939629 0401 HT UBE2V2 TIGD6 26496610,26496610 0007,0004 HT UBE2V2 USP34 22939629 0401 HT UBE2V2 TTC9C 22939629 0401 HT UBE2V2 USP9X 22939629 0401 HT UBE2V2 ZFYVE19 22939629 0401 HT UBE2V2 ARHA 26496610 0004 HT UBE2V2 POLK 26496610,26496610 0007,0004 HT UBE2V2 STUB1 22939629 0401 HT UBE2V2 TRAF6 17353931 0006 HT UBE2V2 HEL-S-71 17964296,11504715,18678647,16112642,14517261,22939629,15749714,16129784,15749714,12847084,16122702,12834344,26344197,18678647,16129784 0096,0096,0004,0096,0096,0401,0096,0096,0018,0096,0004,0096,0401,0018,0018 LC,HT CPLX1 UBE2V2 22939629 0401 HT SSSCA1 UBE2V2 22939629 0401 HT EIF1B UBE2V2 17353931 0006 HT ZPR1 UBE2V2 22939629 0401 HT VPS26A UBE2V2 22939629 0401 HT UBXN7 UBE2V2 22939629 0401 HT ZRANB2 UBE2V2 22939629 0401 HT CD2BP2 UBE2V2 22939629 0401 HT ATP6V1B2 UBE2V2 22939629 0401 HT RAD23B UBE2V2 22939629 0401 HT UBE2M UBE2V2 26344197 0401 HT UBE2N UBE2V2 27173435 0676 HT RHOA UBE2V2 26496610 0007 HT UFM1 UBE2V2 22939629 0401 HT UBE2B UBE2V2 22939629 0401 HT RPS21 UBE2V2 22939629 0401 HT UBE2L3 UBE2V2 22939629 0401 HT UBXN1 UBE2V2 22939629 0401 HT UBE2V1 UBE2V2 22939629 0401 HT TTLL12 UBE2V2 22939629 0401 HT SEC23A UBE2V2 22939629 0401 HT UBE2V2 ZYX 22939629 0401 HT UBE2V2 TIGD6 26496610,26496610 0007,0004 HT UBE2V2 USP34 22939629 0401 HT UBE2V2 TTC9C 22939629 0401 HT UBE2V2 USP9X 22939629 0401 HT UBE2V2 ZFYVE19 22939629 0401 HT UBE2V2 ARHA 26496610 0004 HT UBE2V2 POLK 26496610,26496610 0007,0004 HT UBE2V2 STUB1 22939629 0401 HT UBE2V2 TRAF6 17353931 0006 HT UBE2V2 HEL-S-71 22939629,26344197 0401,0401 HT UBC UBE2V2 11504715,12834344,12834344 0096,0114,0096 LC UBE2N UBE2V2 14517261,16129784,16122702,12834344,16129784 0096,0096,0004,0096,0018 LC HLTF UBE2V2 18316726,18316726,18316726,22904075 0004,0007,0096,0096 LC UBE2V2 HEL-S-71 17964296,11504715,18678647,16112642,14517261,15749714,16129784,15749714,12847084,16122702,12834344,18678647,16129784 0096,0096,0004,0096,0096,0096,0096,0018,0096,0004,0096,0018,0018 LC CPLX1 UBE2V2 22939629 0401 LC SSSCA1 UBE2V2 22939629 0401 LC ZPR1 UBE2V2 22939629 0401 LC VPS26A UBE2V2 22939629 0401 LC UBXN7 UBE2V2 22939629 0401 LC ZRANB2 UBE2V2 22939629 0401 LC CD2BP2 UBE2V2 22939629 0401 LC BCL10 UBE2V2 14695475,14695475,14695475,14695475 0096,0004,0019,0007 LC EGFR UBE2V2 20029029,20029029 0090,0112 LC UBC UBE2V2 12569095,17218787,12834344,16518696,12834344 0114,0114,0114,0114,0096 LC ATP6V1B2 UBE2V2 22939629 0401 LC RNF144A UBE2V2 19549727,19549727 0397,0018 HT USP14 UBE2V2 19549727 0018 HT RAD23B UBE2V2 22939629 0401 LC UBE2M UBE2V2 26344197 0401 LC UBE2N UBE2V2 19549727,18316726,25909880,11473244,16129784,12569095,11473255,16215985,25423605,11473255,16129784,21114314,15147900,11460167 0018,0018,0114,0018,0096,0114,0018,0018,0114,0114,0018,0114,0018,0019 HT,LC UFM1 UBE2V2 22939629 0401 LC UBE2B UBE2V2 22939629 0401 LC RPS21 UBE2V2 22939629 0401 LC UBE2L3 UBE2V2 22939629 0401 LC XIAP UBE2V2 19549727,19549727 0397,0018 HT UBXN1 UBE2V2 22939629 0401 LC TRIM32 UBE2V2 21143188,21143188 0018,0004 LC MKRN3 UBE2V2 19549727,19549727 0397,0018 HT UBE2V1 UBE2V2 22939629 0401 LC SNTA1 UBE2V2 19549727 0018 HT TTLL12 UBE2V2 22939629 0401 LC SEC23A UBE2V2 22939629 0401 LC UBE2V2 ZYX 22939629 0401 LC UBE2V2 LRIF1 16169070 0018 HT UBE2V2 RIF1 16169070 0398 HT UBE2V2 USP34 22939629 0401 LC UBE2V2 DZIP3 19549727,19549727 0397,0018 HT UBE2V2 SIAH1 19549727,19549727 0397,0018 HT UBE2V2 TTC9C 22939629 0401 LC UBE2V2 ZNRF1 19549727,19549727 0397,0018 HT UBE2V2 USP9X 22939629 0401 LC UBE2V2 MALSU1 19549727 0018 HT UBE2V2 IGSF21 16169070,16169070 0018,0398 HT UBE2V2 ZFYVE19 22939629 0401 LC UBE2V2 RNF2 19549727,19549727 0397,0018 HT UBE2V2 TRIM5 19549727,19549727 0397,0018 HT UBE2V2 SUV39H2 16169070,16169070 0018,0398 HT UBE2V2 STUB1 22939629 0401 LC UBE2V2 MOB4 16169070,16169070 0018,0398 HT UBE2V2 HEL-S-71 18678647,22939629,18316726,26148049,25909880,15749714,11473244,16129784,15749714,12569095,11473255,16215985,26344197,18678647,11473255,21114314,15147900,16129784 0004,0401,0018,0114,0114,0096,0018,0096,0018,0114,0018,0018,0401,0018,0114,0114,0018,0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q15819 O14810 UBE2V2 CPLX1 0.081 22939629 Q15819 P61081 UBE2V2 UBE2M 0.081 26344197 Q15819 P61089 UBE2V2 UBE2N 0.309 12039045 Q5TC82 Q15819 RC3H1 UBE2V2 0.309 26489670 Q5UIP0 Q15819 RIF1 UBE2V2 0.126 16169070 Q15819 P61586 UBE2V2 RHOA 0.126 26496610 Q8N5M4 Q15819 TTC9C UBE2V2 0.081 22939629 Q9HBD1 Q15819 RC3H2 UBE2V2 0.309 26489670 Q15819 O60232 UBE2V2 SSSCA1 0.081 22939629 Q8ND25 Q15819 ZNRF1 UBE2V2 0.376 19549727 Q8IUQ4 Q15819 SIAH1 UBE2V2 0.376 19549727 Q9Y3C5 Q15819 RNF11 UBE2V2 0.21 23751493 Q15819 O76064 UBE2V2 RNF8 0.309 22589545 Q15819 O95400 UBE2V2 CD2BP2 0.081 22939629 Q15819 O95999 UBE2V2 BCL10 0.309 14695475 Q94A97 Q15819 UBC35 UBE2V2 0.82 16786304 Q99K95 Q15819 RTFDC1 UBE2V2 0.236 26496610 Q15819 Q149N8 UBE2V2 SHPRH 0.454 17108083 Q86Y13 Q15819 DZIP3 UBE2V2 0.286 19549727 Q9C035 Q15819 TRIM5 UBE2V2 0.286 19549727 Q15819 Q14527 UBE2V2 HLTF 0.659 18316726 Q15819 P0CG48 UBE2V2 UBC 0.843 12834344,16518696,11504715,12569095 Q15819 P61088 UBE2V2 UBE2N 1 16112642,21114314,27173435,16122702,11473255,15147900,12834344,unassigned1312,16129784,11504715,19549727,25909880,16215985,18678647,14517261,26344197,17964296,15749714,12569095,26148049 Q96EH3 Q15819 MALSU1 UBE2V2 0.183 19549727 Q96FW1 Q15819 OTUB1 UBE2V2 0.309 22679021 Q96ID5 Q15819 IGSF21 UBE2V2 0.286 16169070 Q99496 Q15819 RNF2 UBE2V2 0.376 19549727 Q9UBT6 Q15819 POLK UBE2V2 0.126 26496610 Q9UDY8 Q15819 MALT1 UBE2V2 0.309 14695475 Q9UNE7 Q15819 STUB1 UBE2V2 0.081 22939629 Q15819 Q13424 UBE2V2 SNTA1 0.332 19549727 Q15819 Q14166 UBE2V2 TTLL12 0.081 22939629 Q15819 P98170 UBE2V2 XIAP 0.376 19549727 Q15819 Q12933 UBE2V2 TRAF2 0.309 20047764 Q15819 Q13064 UBE2V2 MKRN3 0.376 19549727 Q15819 P50876 UBE2V2 RNF144A 0.376 19549727 Q15819 Q15436 UBE2V2 SEC23A 0.081 22939629 Q15819 Q13404 UBE2V2 UBE2V1 0.081 22939629 Q15819 P63220 UBE2V2 RPS21 0.081 22939629 Q15819 O60739 UBE2V2 EIF1B 0.236 17353931 Q15819 O75312 UBE2V2 ZPR1 0.081 22939629 Q15819 O75436 UBE2V2 VPS26A 0.081 22939629 Q15819 O94888 UBE2V2 UBXN7 0.081 22939629 Q15819 O95218 UBE2V2 ZRANB2 0.081 22939629 Q15819 P00533 UBE2V2 EGFR 0.286 20029029 Q15819 P21281 UBE2V2 ATP6V1B2 0.081 22939629 Q15819 P54578 UBE2V2 USP14 0.332 19549727 Q15819 P61960 UBE2V2 UFM1 0.081 22939629 Q15819 Q04323 UBE2V2 UBXN1 0.081 22939629 Q15819 Q13049 UBE2V2 TRIM32 0.416 21143188 Q15942 Q15819 ZYX UBE2V2 0.081 22939629 Q5T3J3 Q15819 LRIF1 UBE2V2 0.183 16169070 Q70CQ2 Q15819 USP34 UBE2V2 0.081 22939629 Q93008 Q15819 USP9X UBE2V2 0.081 22939629 Q96K21 Q15819 ZFYVE19 UBE2V2 0.081 22939629 Q9FZ48 Q15819 UBC36 UBE2V2 0.671 16786304 Q9H5I1 Q15819 SUV39H2 UBE2V2 0.126 16169070 Q9Y3A3 Q15819 MOB4 UBE2V2 0.286 16169070 Q9Y4K3 Q15819 TRAF6 UBE2V2 0.126 17353931 Q15819 P68036 UBE2V2 UBE2L3 0.081 22939629 Q17RP2 Q15819 TIGD6 UBE2V2 0.126 26496610

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 PFDN6 UBE2V2 MI:0362 inference MI:0461 interaction database REV3L UBE2V2 MI:0362 inference MI:0461 interaction database EIF1B UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database DNAJA2 UBE2V2 MI:0362 inference MI:0461 interaction database NBN UBE2V2 MI:0362 inference MI:1106 pathways database KDM4A UBE2V2 MI:0362 inference MI:1106 pathways database WDHD1 UBE2V2 MI:0362 inference MI:0461 interaction database RNF8 UBE2V2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database KDM4B UBE2V2 MI:0362 inference MI:1106 pathways database HERC2 UBE2V2 MI:0362 inference MI:1106 pathways database BCL10 UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database CHEK2 UBE2V2 MI:0362 inference MI:1106 pathways database WHSC1 UBE2V2 MI:0362 inference MI:1106 pathways database OTC UBE2V2 MI:0362 inference MI:0461 interaction database EGFR UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database ENO1 UBE2V2 MI:0362 inference MI:0461 interaction database GPI UBE2V2 MI:0362 inference MI:0461 interaction database ENO2 UBE2V2 MI:0362 inference MI:0461 interaction database PARP1 UBE2V2 MI:0362 inference MI:1106 pathways database UBB UBE2V2 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBC UBE2V2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HSPA1B UBE2V2 MI:0362 inference MI:0461 interaction database TXN UBE2V2 MI:0362 inference MI:0461 interaction database HSPD1 UBE2V2 MI:0362 inference MI:0461 interaction database HSPA8 UBE2V2 MI:0362 inference MI:0461 interaction database PCNA UBE2V2 MI:0362 inference MI:0461 interaction database XRCC6 UBE2V2 MI:0362 inference MI:1106 pathways database XRCC5 UBE2V2 MI:0362 inference MI:1106 pathways database EEF2 UBE2V2 MI:0362 inference MI:0461 interaction database ENO3 UBE2V2 MI:0362 inference MI:0461 interaction database ATP6V1B1 UBE2V2 MI:0362 inference MI:0461 interaction database NME1 UBE2V2 MI:0362 inference MI:0461 interaction database H2AFX UBE2V2 MI:0362 inference MI:1106 pathways database HSPA6 UBE2V2 MI:0362 inference MI:0461 interaction database ERCC2 UBE2V2 MI:0362 inference MI:1106 pathways database ERCC3 UBE2V2 MI:0362 inference MI:1106 pathways database ATP6V1B2 UBE2V2 MI:0362 inference MI:0461 interaction database UBA1 UBE2V2 MI:0362 inference MI:0461 interaction database NME2 UBE2V2 MI:0362 inference MI:0461 interaction database XPA UBE2V2 MI:0362 inference MI:1106 pathways database PPIB UBE2V2 MI:0362 inference MI:0461 interaction database RBL1 UBE2V2 MI:0362 inference MI:0461 interaction database MAT2A UBE2V2 MI:0362 inference MI:0461 interaction database DNAJA1 UBE2V2 MI:0362 inference MI:0461 interaction database GTF2H1 UBE2V2 MI:0362 inference MI:1106 pathways database HSPA1L UBE2V2 MI:0362 inference MI:0461 interaction database BRCA1 UBE2V2 MI:0362 inference MI:1106 pathways database CETN2 UBE2V2 MI:0362 inference MI:1106 pathways database BRCC3 UBE2V2 MI:0362 inference MI:1106 pathways database NEDD4 UBE2V2 MI:0362 inference MI:0461 interaction database UBE2A UBE2V2 MI:0362 inference MI:0461 interaction database MRE11A UBE2V2 MI:0362 inference MI:1106 pathways database RNF144A UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database PPP5C UBE2V2 MI:0362 inference MI:1106 pathways database CLTCL1 UBE2V2 MI:0362 inference MI:0461 interaction database USP14 UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database HSPA2 UBE2V2 MI:0362 inference MI:0461 interaction database RAD23B UBE2V2 MI:0362 inference MI:1106 pathways database SUMO3 UBE2V2 MI:0362 inference MI:1106 pathways database UBE2G2 UBE2V2 MI:0362 inference MI:0461 interaction database UBE2N UBE2V2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RHOA UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database SUMO2 UBE2V2 MI:0362 inference MI:1106 pathways database CALM1 UBE2V2 MI:0362 inference MI:0461 interaction database HIST1H4A UBE2V2 MI:0362 inference MI:1106 pathways database RBX1 UBE2V2 MI:0362 inference MI:1106 pathways database RPS27A UBE2V2 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBA52 UBE2V2 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBE2B UBE2V2 MI:0362 inference MI:0461 interaction database SUMO1 UBE2V2 MI:0362 inference MI:1106 pathways database UBE2I UBE2V2 MI:0362 inference MI:1106 pathways database RNF4 UBE2V2 MI:0362 inference MI:1106 pathways database DLG4 UBE2V2 MI:0362 inference MI:0461 interaction database XIAP UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database MAT1A UBE2V2 MI:0362 inference MI:0461 interaction database CLTC UBE2V2 MI:0362 inference MI:0461 interaction database XPC UBE2V2 MI:0362 inference MI:1106 pathways database TP53BP1 UBE2V2 MI:0362 inference MI:1106 pathways database TRAF2 UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database CDC16 UBE2V2 MI:0362 inference MI:0461 interaction database TRIM32 UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database MKRN3 UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database ATM UBE2V2 MI:0362 inference MI:1106 pathways database SNTA1 UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database CUL4A UBE2V2 MI:0362 inference MI:1106 pathways database CUL4B UBE2V2 MI:0362 inference MI:1106 pathways database GTF2H2 UBE2V2 MI:0362 inference MI:1106 pathways database GTF2H3 UBE2V2 MI:0362 inference MI:1106 pathways database NFYC UBE2V2 MI:0362 inference MI:0461 interaction database HLTF UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database MDC1 UBE2V2 MI:0362 inference MI:1106 pathways database SHPRH UBE2V2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 DDB1 MI:0362 inference MI:1106 pathways database UBE2V2 HIST3H3 MI:0362 inference MI:1106 pathways database UBE2V2 UGP2 MI:0362 inference MI:0461 interaction database UBE2V2 TATDN3 MI:0362 inference MI:0461 interaction database UBE2V2 TIGD6 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 UBE2NL MI:0362 inference MI:0461 interaction database UBE2V2 LRIF1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 RC3H1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 RIF1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database UBE2V2 RPGRIP1L MI:0362 inference MI:0461 interaction database UBE2V2 FAM175A MI:0362 inference MI:1106 pathways database UBE2V2 RNF111 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBE2V2 PAXIP1 MI:0362 inference MI:1106 pathways database UBE2V2 GTF2H5 MI:0362 inference MI:1106 pathways database UBE2V2 CHD1L MI:0362 inference MI:1106 pathways database UBE2V2 DZIP3 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 SIAH1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 RNF168 MI:0362 inference MI:1106 pathways database UBE2V2 NUP93 MI:0362 inference MI:0461 interaction database UBE2V2 PIAS4 MI:0362 inference MI:1106 pathways database UBE2V2 ZNRF1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 DNAJA4 MI:0362 inference MI:0461 interaction database UBE2V2 DDB2 MI:0362 inference MI:1106 pathways database UBE2V2 GTF2H4 MI:0362 inference MI:1106 pathways database UBE2V2 RAD50 MI:0362 inference MI:1106 pathways database UBE2V2 KAT5 MI:0362 inference MI:1106 pathways database UBE2V2 FBXO32 MI:0362 inference MI:0461 interaction database UBE2V2 MALSU1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 OTUB1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 IGSF21 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 NEDD4L MI:0362 inference MI:0461 interaction database UBE2V2 TRPM7 MI:0362 inference MI:0461 interaction database UBE2V2 UIMC1 MI:0362 inference MI:1106 pathways database UBE2V2 DCLRE1C MI:0362 inference MI:1106 pathways database UBE2V2 PFDN5 MI:0362 inference MI:0461 interaction database UBE2V2 RNF2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 BARD1 MI:0362 inference MI:1106 pathways database UBE2V2 RTFDC1 MI:0362 inference MI:0461 interaction database UBE2V2 TRIM5 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 SUV39H2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 RC3H2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 RAD18 MI:0362 inference MI:0461 interaction database UBE2V2 BABAM1 MI:0362 inference MI:1106 pathways database UBE2V2 BRE MI:0362 inference MI:1106 pathways database UBE2V2 POLK MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 MALT1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 PFDN2 MI:0362 inference MI:0461 interaction database UBE2V2 MOB4 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 REXO2 MI:0362 inference MI:0461 interaction database UBE2V2 RNF11 MI:0045 experimental interaction detection MI:0461 interaction database UBE2V2 TRAF6 MI:0045 experimental interaction detection MI:0461 interaction database