PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus NSMCE1 NSMCE1 18086888 biogrid exp G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G PMF1 NSMCE1 26186194 biogrid exp G G G G G GP G GP GP G GP G GP G G G GP G G G G GP G G G G GP GP G EID3 NSMCE1 21364888,18086888,26186194 biogrid,intact exp G G P P P P P G G G G GP G NSMCE1 OBFC1 26186194 biogrid exp G G G G G GP G GP GP G GP G G G G GP GP G G G G GP GP G GP G G GP G NSMCE1 MAGEF1 20864041 biogrid,intact exp G G G G GP GP G G GP G GP G GP GP G GP GP G GP G G GP G GP GP G GP GP G SMC5 NSMCE1 18086888,16055714,26344197,26186194 biogrid,intact exp G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G UBE2D2 NSMCE1 22992278 biogrid exp G G G G GP GP G G GP G GP GP GP GP G G GP G GP G G GP G GP G G GP GP G NSMCE1 ZNF597 26186194 biogrid exp P P P GP FAM178A NSMCE1 26186194 biogrid exp G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G MAGEA1 NSMCE1 21364888 intact exp P P P GP UBC NSMCE1 22992278 biogrid exp G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G NSMCE1 NSMCE4A 18086888,26186194 biogrid,intact exp G G G G GP GP G GP GP G GP G G G G GP GP G G G G GP GP GP GP G GP P G SIMC1 NSMCE1 26186194 biogrid exp G G G G G GP G GP GP G GP GP GP GP G GP GP G GP G G G GP G GP G GP GP G NSMCE1 NDNL2 21364888,18086888,26344197,26186194,20864041 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NSMCE1 NSMCE2 18086888,26344197,26186194, 21836163 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NSMCE1 SMC6 18086888,14701739,26344197,26186194,26496610, 16082366 biogrid,intact exp, pred G G G G GP GP G GP GP G GP GP GP G G GP GP G GP G G G GP GP GP G GP GP GTF2H2C, GTF2H2C_2 NSMCE1 23023127 pred UBE2D3 NSMCE1 23023127 pred G G G G GP GP G G GP G GP GP GP GP G G GP G GP G G GP G GP G G GP GP G SYCP1 NSMCE1 21836163 pred P G P G G GP G POLD2 NSMCE1 23023127 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G G G G G GP G GP GP G NSMCE1 EME1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G PDS5A NSMCE1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G FAM9C NSMCE1 21836163 pred P P P P G P NSMCE1 USP16 21836163 pred G G G G GP GP G GP GP G GP G GP GP G GP GP G GP G G GP G GP GP G GP GP G ESCO1 NSMCE1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP NSMCE1 USP44 21836163 pred P P P P P P P P P P GP G P P P P P GP KIF22 NSMCE1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G NSMCE1 PARP3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G NSMCE1 CIB1 23023127 pred G G G G G GP G GP GP G GP GP G G G GP GP G GP G G GP GP GP GP G GP GP G NSMCE1 PHF21A 21836163 pred G G G G GP GP G GP GP G GP G GP G G GP GP G P G G GP GP G GP G G GP G SYCP3 NSMCE1 21836163 pred G G G G G G G GP UBE2B NSMCE1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SGOL1 NSMCE1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G P GP GP GP G GP GP G IFI16 NSMCE1 23023127 pred G G G G GP GP G G GP G GP G G GP G G GP G G G G G G G G G G G G AKAP8 NSMCE1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G WAPAL NSMCE1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G TOP3A NSMCE1 21836163 pred G G G G GP GP G G GP G GP G GP GP G G GP G GP G G GP GP GP G G GP GP G NSMCE1 RMI1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G NSMCE1 AUP1 23023127 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G FAM9A NSMCE1 21836163 pred P P P P P P P P P P P RAD21 NSMCE1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G UBE2A NSMCE1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMC1A NSMCE1 21836163 pred G G G G GP GP G GP GP G GP G GP GP G GP GP G GP G G GP GP GP GP G GP GP G H2BFWT NSMCE1 21836163 pred P P P P P P P P P P P P P P DTX3L NSMCE1 23023127 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G G G G G GP GP GP G GP GP G KNTC1 NSMCE1 21836163 pred G G GP P P GP P P GP G GP P G P P P GP G GP GP CDC45 NSMCE1 21836163 pred P P P P P P P P P P G P GP NSMCE1 STAG1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G NSMCE1 DSN1 21836163 pred G G G G GP P G GP GP GP GP P GP G GP P G P G GP GP P GP G GP GP NSMCE1 TTF2 21836163 pred G G G G P P GP P P P GP G GP P P G P P P GP G GP GP NSMCE1 MDFI 21836163 pred G G G P G P P G G P G GP G G G GP P G NSMCE1 SYCP2 21836163 pred G ESPL1 NSMCE1 21836163 pred G G G G GP GP GP GP G GP GP GP GP G GP GP G GP G G P GP GP GP G GP GP G NSMCE1 CDC23 21836163 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G G GP GP GP GP G GP GP G APITD1 NSMCE1 21836163 pred MSH4 NSMCE1 21836163 pred G GP P G P GP P P P P P P G P G P P P P GP G REC8 NSMCE1 21836163 pred G G G G GP GP G G GP G G G GP GP G G GP G GP G G G GP GP G G G GP G HIST1H1T NSMCE1 21836163 pred G G G UBE2N NSMCE1 23023127 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G NSMCE1 ZWILCH 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP P GP GP G GP GP NSMCE1 ANAPC2 21836163 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G G GP GP G GP G GP GP G FAM9B NSMCE1 21836163 pred P P P P P P P P P P P P P P P P P DMC1 NSMCE1 21836163 pred G G G G G G G G G G G G G G G G G G G GP G NSMCE1 RAD18 23023127, 21836163 pred P P P P GP P P G P G P NCAPD3 NSMCE1 21836163 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP G GP GP G SLURP1 NSMCE1 21836163 pred G P P P P P P P P P P P P P P P NSMCE1 DDX12P 21836163 pred NSMCE1 DDX11 21836163 pred G G G G GP GP G GP GP G GP G GP GP G GP GP G GP G G GP GP GP GP G GP GP G NSMCE1 PTTG2 21836163 pred P P P P P P P P P P P P P P P GTF2H2 NSMCE1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G H3F3C NSMCE1 21836163 pred P P P P P P P P P P P P P P P P P STAG2 NSMCE1 21836163 pred G G G G G GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G NSMCE1 CHTF18 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8WV22 affinity chromatography technology 18086888 physical association X 2 Q8WV22 affinity chromatography technology 18086888 physical association X 2 Q8WV22 affinity chromatography technology 18086888 physical association X 2 Q8WV22 biochemical 18086888 colocalization X 2 Q8WV22 P0CG48 affinity chromatography technology 18086888 physical association X 2 Q8WV22 P0CG48 enzymatic study 22992278 direct interaction X 2 Q8WV22 P61087 pull down 22992278 direct interaction X 2 Q8WV22 P0CG48 affinity chromatography technology 24816145 physical association X 2 Q8WV22 P0CG48 affinity chromatography technology 21139048 physical association X 2 Q8WV22 P0CG48 affinity chromatography technology 21890473 physical association X 2 Q8WV22 Q96SB8 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q96SB8 affinity chromatography technology 18086888 physical association X 2 Q8WV22 A0A024R9J6 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q8N140 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q96MG7 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q8IY18 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q96SB8 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q8WV22 affinity chromatography technology 18086888 physical association X 2 Q8WV22 A0A024R9J6 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q96MG7 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q8IY18 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q96MG7 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q8WV22 affinity chromatography technology 18086888 physical association X 2 Q8WV22 Q8IY18 biochemical 18086888 colocalization X 2 Q8WV22 Q96SB8 biochemical 18086888 colocalization X 2 Q8WV22 A0A024R9J6 biochemical 18086888 colocalization X 2 Q8WV22 Q96MG7 biochemical 18086888 colocalization X 2 Q8WV22 Q8IY18 affinity chromatography technology 16055714 physical association X 2 Q8WV22 P62837 pull down 22992278 direct interaction X 2 Q8WV22 Q96MG7 affinity chromatography technology 21364888 physical association X 2 Q8WV22 Q8N140 affinity chromatography technology 21364888 physical association X 2 Q8WV22 Q96SB8 affinity chromatography technology 14701739 physical association X 2 Q8WV22 Q924W5 affinity chromatography technology 20360068 physical association X 2 Q8WV22 Q96MG7 affinity chromatography technology 20864041 physical association X 2 Q8WV22 Q96MG7 affinity chromatography technology 20864041 physical association X 2 Q8WV22 Q96MG7 pull down 20864041 direct interaction X 2 Q8WV22 Q9HAY2 pull down 20864041 direct interaction X 2 Q8WV22 Q96MG7 pull down 20864041 direct interaction X 2 Q8WV22 P61956-2 affinity chromatography technology 19471022 physical association X 2 Q8WV22 anti bait coimmunoprecipitation 18086888 association C 6 Q8WV22 anti bait coimmunoprecipitation 18086888 association C 6 Q8WV22 molecular sieving 18086888 physical association C 6 Q8WV22 anti bait coimmunoprecipitation 18086888 association C 6 Q8WV22 anti bait coimmunoprecipitation 18086888 association C 3 Q8WV22 anti tag coimmunoprecipitation 18086888 association C 3 Q8WV22 anti tag coimmunoprecipitation 21364888 association C 3 Q8WV22 anti tag coimmunoprecipitation 21364888 association C 3 Q8WV22 tandem affinity purification 20360068 physical association C 9 Q8WV22 anti tag coimmunoprecipitation 21364888 association C 3 Q8WV22 anti tag coimmunoprecipitation 18086888 association C 3 Q8WV22 anti tag coimmunoprecipitation 18086888 association C 3 Q8WV22 tandem affinity purification 20864041 association C 3 Q8WV22 Q96SB8 anti tag coimmunoprecipitation 14701739 physical association X 2 Q8WV22 Q96SB8 anti bait coimmunoprecipitation 18086888 physical association X 2 Q8WV22 Q96SB8 anti bait coimmunoprecipitation 18086888 physical association X 2 Q8WV22 Q96MG7 molecular sieving 20864041 physical association X 2 Q8WV22 Q96MG7 x-ray crystallography 20864041 direct interaction X 2 Q8WV22 Q9HAY2 pull down 20864041 physical association X 2 Q8WV22 Q96MG7 pull down 20864041 physical association X 2 Q8WV22 Q96MG7 pull down 20864041 physical association X 2 Q8WV22 Q96MG7 pull down 20864041 physical association X 2 Q8WV22 Q96MG7 anti tag coimmunoprecipitation 20864041 physical association X 2 Q8WV22 Q96MG7 fluorescence microscopy 20864041 colocalization X 2 Q8WV22 Q96MG7 pull down 20864041 direct interaction X 2 Q8WV22 Q96MG7 two hybrid 21364888 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B EID3 NSMCE1 MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation) 18086888,21364888 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (biogrid)|(biogrid)|(intact) BIOGRID_252394|BIOGRID_217874|UniProt_92539 bait|bait|bait prey|prey|prey SUMO2 NSMCE1 MI:0004(affinity chromatography technology) 19471022 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_183168 bait prey NSMCE1 MAGEF1 MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification) 20864041 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_164428|UniProt_108257 bait|bait prey|prey NSMCE2 NSMCE1 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18086888 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association) (intact)|(biogrid)|(biogrid)|(biogrid) UniProt_92534|BIOGRID_217881|BIOGRID_217898|BIOGRID_217870 prey|prey|prey|prey bait|bait|bait|bait NSMCE1 NSMCE4A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation) 18086888 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0914(association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact) BIOGRID_217893|BIOGRID_217882|BIOGRID_217899|BIOGRID_217872|UniProt_92538 bait|bait|bait|prey|prey prey|prey|prey|bait|bait UBC NSMCE1 MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 18086888,21139048,21890473,22992278 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_227319|BIOGRID_169887|BIOGRID_217904|BIOGRID_227310|BIOGRID_175401 prey|bait|bait|prey|bait bait|prey|prey|bait|prey SMC6 NSMCE1 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 14701739,18086888 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact) UniProt_92534|UniProt_92537|UniProt_92536|UniProt_92543|UniProt_92542|UniProt_73481|BIOGRID_217869|BIOGRID_217897|BIOGRID_217879|BIOGRID_257846|BIOGRID_217868|UniProt_92532|UniProt_92533 prey|prey|bait|neutral component|prey|prey|bait|prey|prey|prey|prey|bait|prey bait|bait|prey|neutral component|bait|bait|prey|bait|bait|bait|bait|prey|bait UBE2D2 NSMCE1 MI:0415(enzymatic study) 22992278 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_227313 prey bait SMC5 NSMCE1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16055714,18086888 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_217892|BIOGRID_217878|BIOGRID_217896|BIOGRID_218286 prey|prey|prey|bait bait|bait|bait|prey NDNL2 NSMCE1 MI:0018(two hybrid)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0676(tandem affinity purification)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0676(tandem affinity purification)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification)|MI:0006(anti bait coimmunoprecipitation) 18086888,20864041,21364888 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0403(colocalization)|MI:0914(association)|MI:0914(association) (intact)|(intact)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(intact)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(biogrid)|(intact)|(intact) UniProt_111730|UniProt_108251|UniProt_108270|BIOGRID_164404|BIOGRID_217883|UniProt_108260|BIOGRID_217894|BIOGRID_164429|UniProt_111727|UniProt_108241|BIOGRID_164426|BIOGRID_251980|UniProt_108237|BIOGRID_217876|BIOGRID_164394|UniProt_108278|UniProt_108258|UniProt_108268|BIOGRID_217900|UniProt_108223|UniProt_92540 bait|prey|neutral component|prey|prey|bait|prey|prey|bait|neutral component|bait|bait|prey|bait|bait|neutral component|bait|bait|prey|bait|bait prey|bait|neutral component|bait|bait|prey|bait|bait|prey|neutral component|prey|prey|bait|prey|prey|neutral component|prey|prey|bait|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality PMF1 NSMCE1 26186194 0004 HT SLF2 NSMCE1 26186194 0004 HT SMC5 NSMCE1 18086888,18086888,18086888,26344197,16055714,26186194,18086888 0006,0401,0071,0401,0004,0004,0004 LC,HT EID3 NSMCE1 18086888,18086888,26186194,21364888,21364888 0004,0007,0004,0007,0004 LC,HT SIMC1 NSMCE1 26186194 0004 HT NSMCE1 ZNF597 26186194 0004 HT NSMCE1 NSMCE2 18086888,18086888,18086888,26344197,26186194,18086888 0006,0401,0071,0401,0004,0004 LC,HT NSMCE1 NSMCE3 18086888,18086888,18086888,26344197,21364888,20864041,26186194,20864041,20864041,20864041,18086888,20864041,21364888,20864041,20864041,18086888,21364888 0006,0401,0071,0401,0018,0007,0004,0096,0004,0114,0007,0676,0007,0071,0416,0004,0004 LC,HT NSMCE1 SMC6 18086888,18086888,18086888,26344197,26496610,26496610,26186194,14701739,14701739,18086888 0006,0401,0071,0401,0004,0007,0004,0004,0007,0004 LC,HT NSMCE1 OBFC1 26186194 0004 HT NSMCE1 NSMCE4A 18086888,18086888,18086888,26186194,18086888,18086888 0006,0401,0071,0004,0007,0004 LC,HT PMF1 NSMCE1 26186194 0004 HT SLF2 NSMCE1 26186194 0004 HT SMC5 NSMCE1 26344197,26186194 0401,0004 HT EID3 NSMCE1 26186194 0004 HT SIMC1 NSMCE1 26186194 0004 HT NSMCE1 ZNF597 26186194 0004 HT NSMCE1 NSMCE2 26344197,26186194 0401,0004 HT NSMCE1 NSMCE3 26344197,26186194 0401,0004 HT NSMCE1 SMC6 26344197,26496610,26496610,26186194 0401,0004,0007,0004 HT NSMCE1 OBFC1 26186194 0004 HT NSMCE1 NSMCE4A 26186194 0004 HT SMC5 NSMCE1 18086888,18086888,18086888,16055714,18086888 0006,0401,0071,0004,0004 LC EID3 NSMCE1 18086888,18086888,21364888,21364888 0004,0007,0007,0004 LC NSMCE1 NSMCE2 18086888,18086888,18086888,18086888 0006,0401,0071,0004 LC NSMCE1 NSMCE3 18086888,18086888,18086888,21364888,20864041,20864041,20864041,20864041,18086888,20864041,21364888,20864041,20864041,18086888,21364888 0006,0401,0071,0018,0007,0096,0004,0114,0007,0676,0007,0071,0416,0004,0004 LC NSMCE1 SMC6 18086888,18086888,18086888,14701739,14701739,18086888 0006,0401,0071,0004,0007,0004 LC NSMCE1 NSMCE4A 18086888,18086888,18086888,18086888,18086888 0006,0401,0071,0007,0004 LC UBC NSMCE1 22992278 0415 LC SMC5 NSMCE1 18086888,18086888,18086888,26344197,18086888 0006,0401,0071,0401,0004 LC NSMCE1 NSMCE2 18086888,18086888,18086888,26344197,18086888 0006,0401,0071,0401,0004 LC NSMCE1 NSMCE3 18086888,18086888,18086888,26344197,21364888,26910052,20864041,20864041,20864041,20864041,18086888,20864041,21364888,20864041,20864041,18086888,21364888 0006,0401,0071,0401,0018,0114,0007,0096,0004,0114,0007,0676,0007,0071,0416,0004,0004 LC NSMCE1 SMC6 18086888,18086888,18086888,26344197,18086888 0006,0401,0071,0401,0004 LC NSMCE1 NSMCE4A 18086888,18086888,18086888,18086888,18086888 0006,0401,0071,0007,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9H668 Q8WV22 OBFC1 NSMCE1 0.126 26186194 Q8WV22 Q8IY18 NSMCE1 SMC5 0.523 16055714,18086888,26186194 Q9NXX6 Q8WV22 NSMCE4A NSMCE1 0.523 18086888,26186194 Q924W5 Q8WV22 SMC6 NSMCE1 0.236 20360068 Q8WV22 Q8N140 NSMCE1 EID3 0.454 21364888,18086888,26186194 Q96SB8 Q8WV22 SMC6 NSMCE1 0.712 26186194,26496610,14701739,18086888 Q96MG7 Q8WV22 NDNL2 NSMCE1 0.888 21364888,26186194,20864041,18086888 Q8WV22 Q8IX21 NSMCE1 FAM178A 0.126 26186194 Q8WV22 P0CG48 NSMCE1 UBC 0.309 22992278 Q8WV22 Q6P1K2 NSMCE1 PMF1 0.126 26186194 Q8WV22 P61087 NSMCE1 UBE2K 0.309 22992278 Q8WV22 P62837 NSMCE1 UBE2D2 0.309 22992278 Q9HAY2 Q8WV22 MAGEF1 NSMCE1 0.309 20864041 Q8WV22 Q8WV22 NSMCE1 NSMCE1 0.236 18086888 Q8WV22 Q8NDZ2 NSMCE1 SIMC1 0.126 26186194 Q96LX8 Q8WV22 ZNF597 NSMCE1 0.126 26186194 Q96MF7 Q8WV22 NSMCE2 NSMCE1 0.445 18086888,26186194,26344197

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 RAD21 NSMCE1 MI:0362 inference MI:1106 pathways database UBC NSMCE1 MI:0045 experimental interaction detection MI:0461 interaction database MAGEA1 NSMCE1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2K NSMCE1 MI:0362 inference MI:0461 interaction database SUMO2 NSMCE1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 NSMCE1 MI:0045 experimental interaction detection MI:0461 interaction database SUMO1 NSMCE1 MI:0362 inference MI:1106 pathways database UBE2I NSMCE1 MI:0362 inference MI:1106 pathways database SMC1A NSMCE1 MI:0362 inference MI:1106 pathways database PMF1 NSMCE1 MI:0045 experimental interaction detection MI:0461 interaction database SLF2 NSMCE1 MI:0045 experimental interaction detection MI:0461 interaction database SMC5 NSMCE1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database EID3 NSMCE1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database STAG2 NSMCE1 MI:0362 inference MI:1106 pathways database SIMC1 NSMCE1 MI:0045 experimental interaction detection MI:0461 interaction database PJA1 NSMCE1 MI:0362 inference MI:0461 interaction database NSMCE1 STAG1 MI:0362 inference MI:1106 pathways database NSMCE1 ZNF597 MI:0045 experimental interaction detection MI:0461 interaction database NSMCE1 NSMCE2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database NSMCE1 NSMCE3 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database NSMCE1 SMC6 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database NSMCE1 OBFC1 MI:0045 experimental interaction detection MI:0461 interaction database NSMCE1 MAGEF1 MI:0045 experimental interaction detection MI:0461 interaction database NSMCE1 NSMCE4A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database NSMCE1 SMC3 MI:0362 inference MI:1106 pathways database