PTM - CPLM Gene Name UniProt ID Type Position Code CHD3 Q12873 Acetylation 894 K CHD3 Q12873 Acetylation 997 K CHD3 Q12873 Acetylation 1222 K CHD3 Q12873 Ubiquitination 1536 K CHD3 Q12873 Ubiquitination 1554 K

PTM - dbPAF Gene Name UniProt ID Position Type Species CHD3 Q12873 1103 Y Homo sapiens(Human) CHD3 Q12873 1205 T Homo sapiens(Human) CHD3 Q12873 1251 S Homo sapiens(Human) CHD3 Q12873 1274 T Homo sapiens(Human) CHD3 Q12873 1282 Y Homo sapiens(Human) CHD3 Q12873 1284 S Homo sapiens(Human) CHD3 Q12873 1285 S Homo sapiens(Human) CHD3 Q12873 1361 S Homo sapiens(Human) CHD3 Q12873 1363 Y Homo sapiens(Human) CHD3 Q12873 1364 S Homo sapiens(Human) CHD3 Q12873 1367 S Homo sapiens(Human) CHD3 Q12873 1532 S Homo sapiens(Human) CHD3 Q12873 1533 S Homo sapiens(Human) CHD3 Q12873 1535 T Homo sapiens(Human) CHD3 Q12873 1537 T Homo sapiens(Human) CHD3 Q12873 1538 S Homo sapiens(Human) CHD3 Q12873 1540 T Homo sapiens(Human) CHD3 Q12873 1541 T Homo sapiens(Human) CHD3 Q12873 1545 S Homo sapiens(Human) CHD3 Q12873 1547 T Homo sapiens(Human) CHD3 Q12873 1549 S Homo sapiens(Human) CHD3 Q12873 1552 T Homo sapiens(Human) CHD3 Q12873 1553 S Homo sapiens(Human) CHD3 Q12873 1557 T Homo sapiens(Human) CHD3 Q12873 1561 S Homo sapiens(Human) CHD3 Q12873 1569 T Homo sapiens(Human) CHD3 Q12873 1587 S Homo sapiens(Human) CHD3 Q12873 1595 T Homo sapiens(Human) CHD3 Q12873 1601 S Homo sapiens(Human) CHD3 Q12873 1605 S Homo sapiens(Human) CHD3 Q12873 1645 S Homo sapiens(Human) CHD3 Q12873 1646 T Homo sapiens(Human) CHD3 Q12873 1815 Y Homo sapiens(Human) CHD3 Q12873 1819 S Homo sapiens(Human) CHD3 Q12873 183 S Homo sapiens(Human) CHD3 Q12873 1850 S Homo sapiens(Human) CHD3 Q12873 1873 S Homo sapiens(Human) CHD3 Q12873 1899 S Homo sapiens(Human) CHD3 Q12873 274 S Homo sapiens(Human) CHD3 Q12873 313 S Homo sapiens(Human) CHD3 Q12873 324 S Homo sapiens(Human) CHD3 Q12873 328 S Homo sapiens(Human) CHD3 Q12873 330 S Homo sapiens(Human) CHD3 Q12873 333 S Homo sapiens(Human) CHD3 Q12873 335 S Homo sapiens(Human) CHD3 Q12873 374 Y Homo sapiens(Human) CHD3 Q12873 376 T Homo sapiens(Human) CHD3 Q12873 381 Y Homo sapiens(Human) CHD3 Q12873 43 S Homo sapiens(Human) CHD3 Q12873 578 Y Homo sapiens(Human) CHD3 Q12873 595 Y Homo sapiens(Human) CHD3 Q12873 597 S Homo sapiens(Human) CHD3 Q12873 712 S Homo sapiens(Human) CHD3 Q12873 713 S Homo sapiens(Human) CHD3 Q12873 715 T Homo sapiens(Human) CHD3 Q12873 724 T Homo sapiens(Human) CHD3 Q12873 73 S Homo sapiens(Human) CHD3 Q12873 739 Y Homo sapiens(Human) CHD3 Q12873 79 S Homo sapiens(Human) CHD3 Q12873 832 S Homo sapiens(Human) CHD3 Q12873 84 Y Homo sapiens(Human) CHD3 Q12873 860 T Homo sapiens(Human) CHD3 Q12873 861 S Homo sapiens(Human) CHD3 Q12873 862 Y Homo sapiens(Human) CHD3 Q12873 866 T Homo sapiens(Human) CHD3 Q12873 874 S Homo sapiens(Human) CHD3 Q12873 88 S Homo sapiens(Human) CHD3 Q12873 90 S Homo sapiens(Human) CHD3 Q12873 93 S Homo sapiens(Human) CHD3 Q12873 95 Y Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q12873 K175-ac Acetylation FMRPLIAkKNPKIPM Q12873 K261-ac Acetylation PIRRAKTkEGkGPGH Q12873 K264-ac Acetylation RAKTkEGkGPGHkRR Q12873 K269-ac Acetylation EGkGPGHkRRsKsPR Q12873 K894-ac Acetylation RLKNNQSkFFRVLNG Q12873 K997-ac Acetylation PMQKKYYkyILtRNF Q12873 K1222-ac Acetylation SKAGSMSkQELDDIL Q12873 K56-m1 Methylation KRKRGPKkQkENKPG Q12873 K58-m1 Methylation KRGPKkQkENKPGkP Q12873 K64-m1 Methylation QkENKPGkPRKRKKR Q12873 R1323-m1 Methylation DyWEKLLrHHYEQQQ Q12873 R1759-m1 Methylation IVLHGYArWQDIQND Q12873 S43-p Phosphorylation DDIRLLPsALGVKKR Q12873 S73-p Phosphorylation RKRKKRDsEEEFGsE Q12873 S79-p Phosphorylation DsEEEFGsERDEYRE Q12873 S88-p Phosphorylation RDEYREKsEsGGsEy Q12873 S90-p Phosphorylation EYREKsEsGGsEyGT Q12873 S93-p Phosphorylation EKsEsGGsEyGTGPG Q12873 Y95-p Phosphorylation sEsGGsEyGTGPGRK Q12873 S183-p Phosphorylation KNPKIPMsKMMTILG Q12873 S272-p Phosphorylation GPGHkRRsKsPRVPD Q12873 S274-p Phosphorylation GHkRRsKsPRVPDGR Q12873 S313-p Phosphorylation GGSYVFQsDEGPEPE Q12873 S324-p Phosphorylation PEPEAEEsDLDsGSV Q12873 S328-p Phosphorylation AEEsDLDsGSVHsAs Q12873 S333-p Phosphorylation LDsGSVHsAsGRPDG Q12873 S335-p Phosphorylation sGSVHsAsGRPDGPV Q12873 T376-p Phosphorylation EEVDGYEtDHQDYCE Q12873 Y595-p Phosphorylation DEPPPLDyGsGEDDG Q12873 S597-p Phosphorylation PPPLDyGsGEDDGKS Q12873 S712-p Phosphorylation LQGDGPPssPtNDPT Q12873 S713-p Phosphorylation QGDGPPssPtNDPTV Q12873 T715-p Phosphorylation DGPPssPtNDPTVKY Q12873 T724-p Phosphorylation DPTVKYEtQPRFITA Q12873 Y739-p Phosphorylation TGGTLHMyQLEGLNW Q12873 S777-p Phosphorylation QTIVFLYsLYKEGHT Q12873 T866-p Phosphorylation LTSYELItIDQAALG Q12873 S874-p Phosphorylation IDQAALGsIRWACLV Q12873 S989-p Phosphorylation LIVRVELsPMQKKYY Q12873 Y998-p Phosphorylation MQKKYYkyILtRNFE Q12873 T1001-p Phosphorylation KYYkyILtRNFEALN Q12873 S1083-p Phosphorylation GHRVLIFsQMTKMLD Q12873 T1274-p Phosphorylation NQDATEDtDVQNMNE Q12873 Y1282-p Phosphorylation DVQNMNEyLssFKVA Q12873 S1284-p Phosphorylation QNMNEyLssFKVAQY Q12873 S1285-p Phosphorylation NMNEyLssFKVAQYV Q12873 Y1317-p Phosphorylation EENVDPDyWEKLLrH Q12873 S1361-p Phosphorylation QEDQDNQsEYsVGsE Q12873 S1364-p Phosphorylation QDNQsEYsVGsEEED Q12873 S1367-p Phosphorylation QsEYsVGsEEEDEDF Q12873 S1532-p Phosphorylation SKRSSRAssPtktSP Q12873 S1533-p Phosphorylation KRSSRAssPtktSPT Q12873 T1535-p Phosphorylation SSRAssPtktSPTtP Q12873 T1537-p Phosphorylation RAssPtktSPTtPEA Q12873 T1541-p Phosphorylation PtktSPTtPEAsAtN Q12873 S1545-p Phosphorylation SPTtPEAsAtNsPCt Q12873 T1547-p Phosphorylation TtPEAsAtNsPCtsk Q12873 S1549-p Phosphorylation PEAsAtNsPCtskPA Q12873 T1552-p Phosphorylation sAtNsPCtskPAtPA Q12873 S1553-p Phosphorylation AtNsPCtskPAtPAP Q12873 T1557-p Phosphorylation PCtskPAtPAPSEKG Q12873 T1569-p Phosphorylation EKGEGIRtPLEKEEA Q12873 T1595-p Phosphorylation RIGEKMEtEADAPsP Q12873 S1601-p Phosphorylation EtEADAPsPAPsLGE Q12873 S1605-p Phosphorylation DAPsPAPsLGERLEP Q12873 S1641-p Phosphorylation YRGDREKsATEstPG Q12873 S1645-p Phosphorylation REKsATEstPGERGE Q12873 T1646-p Phosphorylation EKsATEstPGERGEE Q12873 S1819-p Phosphorylation RAAYLNLsQEPAHPA Q12873 S1850-p Phosphorylation HQHLSKEsLAGNKPA Q12873 S1873-p Phosphorylation NQLEELLsDMkADVt Q12873 T1880-p Phosphorylation sDMkADVtRLPATLS Q12873 S1899-p Phosphorylation IAARLQMsERSILSR Q12873 K627-sm Sumoylation KYYRFGIkPEWMTVH Q12873 K1238-sm Sumoylation FGTEELFkDENEGEN Q12873 K1308-sm Sumoylation EIEREIIkQEENVDP Q12873 K1394-sm Sumoylation QLRNEKDkPLPPLLA Q12873 K969-ub Ubiquitination PHMLRRLkADVFkNM Q12873 K974-ub Ubiquitination RLkADVFkNMPAkTE Q12873 K979-ub Ubiquitination VFkNMPAkTELIVRV Q12873 K997-ub Ubiquitination PMQKKYYkyILtRNF Q12873 K1067-ub Ubiquitination GKLMLLQkMLRKLKE Q12873 K1394-ub Ubiquitination QLRNEKDkPLPPLLA Q12873 K1536-ub Ubiquitination SRAssPtktSPTtPE Q12873 K1554-ub Ubiquitination tNsPCtskPAtPAPS Q12873 K1876-ub Ubiquitination EELLsDMkADVtRLP

PTM - dbPTM UniProt ID Position Code Type Resources References Q12873 43 S Phosphorylation Swiss-Prot 1010711 18187866 Q12873 324 S Phosphorylation Swiss-Prot 1010711 17081983 Q12873 713 S Phosphorylation Swiss-Prot 1010711 15302935;17081983;18669648;18691976;19413330;19690332 Q12873 1361 S Phosphorylation Swiss-Prot 1010711 18669648 Q12873 1364 S Phosphorylation Swiss-Prot 1010711 18669648 Q12873 1367 S Phosphorylation Swiss-Prot 1010711 18669648 Q12873 1549 S Phosphorylation Swiss-Prot 1010711 19413330 Q12873 1601 S Phosphorylation Swiss-Prot 1010711 15302935;17081983;18669648;18691976;19413330;19690332 Q12873 1605 S Phosphorylation Swiss-Prot 1010711 17081983;18669648;19413330;19690332 Q12873 73 S Phosphorylation PhosphoELM.10011 17081983 Q12873 79 S Phosphorylation PhosphoELM.10011 17081983 Q12873 324 S Phosphorylation PhosphoELM.10011 17081983 Q12873 713 S Phosphorylation PhosphoELM.10011 17081983;15302935 Q12873 1601 S Phosphorylation PhosphoELM.10011 17081983;15302935 Q12873 1605 S Phosphorylation PhosphoELM.10011 17081983 Q12873 73 S Phosphorylation HPRD 9.0 17081983 Q12873 79 S Phosphorylation HPRD 9.0 17081983 Q12873 324 S Phosphorylation HPRD 9.0 17081983,18452278 Q12873 597 S Phosphorylation HPRD 9.0 19651622,18452278 Q12873 712 S Phosphorylation HPRD 9.0 20068231 Q12873 713 S Phosphorylation HPRD 9.0 15302935,18669648,19413330,18691976,19651622,18452278,20068231 Q12873 861 S Phosphorylation HPRD 9.0 20068231 Q12873 874 S Phosphorylation HPRD 9.0 20068231 Q12873 1361 S Phosphorylation HPRD 9.0 18669648 Q12873 1364 S Phosphorylation HPRD 9.0 18669648,18452278 Q12873 1367 S Phosphorylation HPRD 9.0 18669648,18452278 Q12873 1549 S Phosphorylation HPRD 9.0 19413330 Q12873 1601 S Phosphorylation HPRD 9.0 17322306,18669648,19413330,18691976,19651622,18452278,18767875,20068231,20058876 Q12873 1601 S Phosphorylation HPRD 9.0 15302935,18669648,19413330,18691976,19651622,18452278,18767875,20068231,20058876 Q12873 1605 S Phosphorylation HPRD 9.0 17081983,18669648,19413330,19651622,18452278,20068231 Q12873 715 T Phosphorylation HPRD 9.0 18669648 Q12873 860 T Phosphorylation HPRD 9.0 20068231 Q12873 866 T Phosphorylation HPRD 9.0 20068231 Q12873 1569 T Phosphorylation HPRD 9.0 20068231 Q12873 84 Y Phosphorylation HPRD 9.0 17081983 Q12873 73 S Phosphorylation SysPTM 1.1 17081983 Q12873 79 S Phosphorylation SysPTM 1.1 17081983 Q12873 324 S Phosphorylation SysPTM 1.1 17081983 Q12873 713 S Phosphorylation SysPTM 1.1 18669648;18691976;17081983 Q12873 1361 S Phosphorylation SysPTM 1.1 18669648 Q12873 1364 S Phosphorylation SysPTM 1.1 18669648 Q12873 1367 S Phosphorylation SysPTM 1.1 18669648 Q12873 1601 S Phosphorylation SysPTM 1.1 18669648;17081983;18691976 Q12873 1605 S Phosphorylation SysPTM 1.1 18669648;17081983 Q12873 84 Y Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References CHD3 132 S Phosphorylation 17081983 CHD3 1361 S Phosphorylation 18669648 CHD3 1364 S Phosphorylation 18669648,18452278 CHD3 1367 S Phosphorylation 18669648,18452278 CHD3 138 S Phosphorylation 17081983 CHD3 1420 S Phosphorylation 18669648 CHD3 1423 S Phosphorylation 18669648,18452278 CHD3 1426 S Phosphorylation 18669648,18452278 CHD3 143 Y Phosphorylation 17081983 CHD3 1549 S Phosphorylation 19413330 CHD3 1569 T Phosphorylation 20068231 CHD3 1601 S Phosphorylation 15302935,18669648,19413330,18691976,19651622,18452278,18767875,20068231,20058876 CHD3 1601 S Phosphorylation 17322306,18669648,19413330,18691976,19651622,18452278,18767875,20068231,20058876 CHD3 1605 S Phosphorylation 17081983,18669648,19413330,19651622,18452278,20068231 CHD3 1608 S Phosphorylation 19413330 CHD3 1628 T Phosphorylation 20068231 CHD3 1660 S Phosphorylation 17322306,18669648,19413330,18691976,19651622,18452278,18767875,20068231,20058876 CHD3 1664 S Phosphorylation 17081983,18669648,19413330,19651622,18452278,20068231 CHD3 324 S Phosphorylation 17081983,18452278 CHD3 383 S Phosphorylation 17081983,18452278 CHD3 597 S Phosphorylation 19651622,18452278 CHD3 656 S Phosphorylation 19651622,18452278 CHD3 66 S Phosphorylation 17081983 CHD3 712 S Phosphorylation 20068231 CHD3 713 S Phosphorylation 15302935,18669648,19413330,18691976,19651622,18452278,20068231 CHD3 715 T Phosphorylation 18669648 CHD3 73 S Phosphorylation 17081983 CHD3 771 S Phosphorylation 20068231 CHD3 772 S Phosphorylation 15302935,18669648,19413330,18691976,19651622,18452278,20068231 CHD3 774 T Phosphorylation 18669648 CHD3 79 S Phosphorylation 17081983 CHD3 84 Y Phosphorylation 17081983 CHD3 860 T Phosphorylation 20068231 CHD3 861 S Phosphorylation 20068231 CHD3 866 T Phosphorylation 20068231 CHD3 874 S Phosphorylation 20068231 CHD3 919 T Phosphorylation 20068231 CHD3 920 S Phosphorylation 20068231 CHD3 925 T Phosphorylation 20068231 CHD3 933 S Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q12873 1601 S 17081983 HTP Phosphorylation Q12873 1601 S 15302935 HTP Phosphorylation Q12873 324 S 17081983 HTP Phosphorylation Q12873 1605 S 17081983 HTP Phosphorylation Q12873 713 S 17081983 HTP Phosphorylation Q12873 713 S 15302935 HTP Phosphorylation Q12873 79 S 17081983 HTP Phosphorylation Q12873 73 S 17081983 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q12873 79 Phosphoserine 23186163 Q12873 324 Phosphoserine 17081983 Q12873 597 Phosphoserine 23186163 Q12873 713 Phosphoserine 18669648;19690332;23186163 Q12873 1367 Phosphoserine 18669648 Q12873 1601 Phosphoserine 17081983;18669648;18691976;19690332;20068231;23186163;24275569 Q12873 1605 Phosphoserine 17081983;18669648;19690332;20068231;23186163 Q12873 1646 Phosphothreonine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type CHD3 IPI00373870 S 1601 TEADAPpSPAPSLG phosphorylation CHD3 IPI00373870 S 1605 APSPAPpSLGERLE phosphorylation CHD3 IPI00373870 S 712 QGDGPPpSSPTNDP phosphorylation CHD3 IPI00373870 S 713 GDGPPSpSPTNDPT phosphorylation CHD3 IPI00373870 T 1569 KGEGIRpTPLEKEE phosphorylation CHD3 IPI00373870 Y 578 IFHLVMpYRNYQRK phosphorylation CHD3 IPI00465222 S 118 KRKKRDpSEEEFGS phosphorylation CHD3 IPI00465222 S 124 SEEEFGpSERDEYR phosphorylation CHD3 IPI00465222 S 1646 TEADAPpSPAPSLG phosphorylation CHD3 IPI00465222 S 1650 APSPAPpSLGERLE phosphorylation CHD3 IPI00465222 S 369 EPEAEEpSDLDSGS phosphorylation CHD3 IPI00465222 S 52 RGRDRHpSPPGCHL phosphorylation CHD3 IPI00465222 S 758 GDGPPSpSPTNDPT phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 1107 107532 - K Ubiquitination 21906983 1107 107532 - K Sumoylation 19471022 1107 107532 - K Sumoylation 21252943 1107 107532 - K Ubiquitination 21890473 1107 107532 - K Ubiquitination 21963094 1107 107532 - K Ubiquitination 22505724 1107 107532 - K Ubiquitination 23000965 1107 107532 - K Ubiquitination 24816145