PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HIST1H1D USP38 26186194 biogrid exp G G G G G HMX3 USP38 19615732 biogrid exp AHSG USP38 26186194 biogrid exp G G HMX2 USP38 19615732 intact exp G G G G G G G G VAV2 USP38 18654987 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G SHFM1 USP38 24811749 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GNB5 USP38 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RPS12 USP38 19615732 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ADAR USP38 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G LGALS7, LGALS7B USP38 19615732 biogrid,intact exp RPL7 USP38 19615732 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP38 USP38 19615732 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HSPB1 USP38 19615732 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8NB14 P04792 affinity chromatography technology 19615732 physical association X 2 Q8NB14 P18124 affinity chromatography technology 19615732 physical association X 2 Q8NB14 P52735 two hybrid 18654987 direct interaction X 2 A6NHT5 Q8NB14 affinity chromatography technology 19615732 physical association X 2 P25398 Q8NB14 affinity chromatography technology 19615732 physical association X 2 P47929 Q8NB14 affinity chromatography technology 19615732 physical association X 2 P60896 Q8NB14 affinity chromatography technology 24811749 physical association X 2 P0CG48 Q8NB14 affinity chromatography technology 22118674 physical association X 2 P0CG48 Q8NB14 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q8NB14 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q8NB14 affinity chromatography technology 21906983 physical association X 2 Q8NB14 anti tag coimmunoprecipitation 24811749 association C 66 Q8NB14 P52735 two hybrid 18654987 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B RPS12 USP38 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100673|BIOGRID_119781 prey|prey bait|bait USP38 HMX3 MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_120872 bait prey HSPB1 USP38 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100673|BIOGRID_119519 prey|prey bait|bait RPL7 USP38 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100673|BIOGRID_119776 prey|prey bait|bait LGALS7 USP38 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100673|BIOGRID_119567 prey|prey bait|bait UBC USP38 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 21139048,21890473,21906983,22118674 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_169714|BIOGRID_173594|BIOGRID_179005|BIOGRID_160352 bait|bait|bait|bait prey|prey|prey|prey VAV2 USP38 MI:0018(two hybrid)|MI:0018(two hybrid) 18654987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_96808|BIOGRID_184855 bait|bait prey|prey

PPI - HINT Gene A Gene B PMID Method Quality HMX2 USP38 19615732 0007 HT HMX3 USP38 19615732 0004 HT GNB5 USP38 26186194 0004 HT AHSG USP38 26186194 0004 HT HSPB1 USP38 19615732,19615732 0004,0007 HT HIST1H1D USP38 26186194 0004 HT RPL7 USP38 19615732,19615732 0004,0007 HT RPS12 USP38 19615732,19615732 0004,0007 HT LGALS7|LGALS7B USP38 19615732,19615732 0004,0007 HT ADAR USP38 26186194 0004 HT USP38 HEL-S-102 19615732 0004 HT HMX2 USP38 19615732 0007 HT HMX3 USP38 19615732 0004 HT GNB5 USP38 26186194 0004 HT AHSG USP38 26186194 0004 HT HSPB1 USP38 19615732,19615732 0004,0007 HT HIST1H1D USP38 26186194 0004 HT RPL7 USP38 19615732,19615732 0004,0007 HT RPS12 USP38 19615732,19615732 0004,0007 HT LGALS7|LGALS7B USP38 19615732,19615732 0004,0007 HT ADAR USP38 26186194 0004 HT USP38 HEL-S-102 19615732 0004 HT VAV2 USP38 18654987 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8NB14 A2RU54 USP38 HMX2 0.126 19615732 Q8NB14 A6NHT5 USP38 HMX3 0.126 19615732 Q8NB14 O14775 USP38 GNB5 0.126 26186194 Q8NB14 P02765 USP38 AHSG 0.126 26186194 Q8NB14 P16402 USP38 HIST1H1D 0.126 26186194 Q8NB14 P52735 USP38 VAV2 0.454 18654987 Q8NB14 P55265 USP38 ADAR 0.126 26186194 Q8NB14 P04792 USP38 HSPB1 0.236 19615732 Q8NB14 P47929 USP38 LGALS7B 0.236 19615732 Q8NB14 P18124 USP38 RPL7 0.236 19615732 Q8NB14 P25398 USP38 RPS12 0.236 19615732 Q8NB14 P60896 USP38 SHFM1 0.236 24811749