Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BRCA 15 50831018 50831018 + Missense_Mutation SNP C C T TCGA-A8-A09Z-01A-11W-A019-09 TCGA-A8-A09Z-10A-01W-A021-09 g.chr15:50831018C>T c.691G>A c.(691-693)Gca>Aca p.A231T CESC 15 50833424 50833424 + Missense_Mutation SNP G G C TCGA-JW-A5VL-01A-11D-A28B-09 TCGA-JW-A5VL-10A-01D-A28E-09 g.chr15:50833424G>C c.482C>G c.(481-483)tCt>tGt p.S161C COAD 15 50793007 50793007 + 3'UTR SNP G G T TCGA-F4-6570-01A-11D-1771-10 TCGA-F4-6570-10A-01D-1771-10 g.chr15:50793007G>T COAD 15 50831018 50831018 + Missense_Mutation SNP C C T TCGA-AA-A01R-01A-21W-A096-10 TCGA-AA-A01R-11A-12W-A096-10 g.chr15:50831018C>T c.691G>A c.(691-693)Gca>Aca p.A231T COAD 15 50835852 50835852 + Missense_Mutation SNP T T G TCGA-AA-3930-01A-01W-0995-10 TCGA-AA-3930-10A-01W-0995-10 g.chr15:50835852T>G c.387A>C c.(385-387)caA>caC p.Q129H COAD 15 50836904 50836904 + Missense_Mutation SNP A A C TCGA-AZ-4315-01A-01D-1408-10 TCGA-AZ-4315-10A-01D-1408-10 g.chr15:50836904A>C c.128T>G c.(127-129)gTc>gGc p.V43G COADREAD 15 50793007 50793007 + 3'UTR SNP G G T TCGA-F4-6570-01A-11D-1771-10 TCGA-F4-6570-10A-01D-1771-10 g.chr15:50793007G>T COADREAD 15 50831000 50831000 + Missense_Mutation SNP C C T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr15:50831000C>T c.709G>A c.(709-711)Gaa>Aaa p.E237K COADREAD 15 50831018 50831018 + Missense_Mutation SNP C C T TCGA-AA-A01R-01A-21W-A096-10 TCGA-AA-A01R-11A-12W-A096-10 g.chr15:50831018C>T c.691G>A c.(691-693)Gca>Aca p.A231T COADREAD 15 50835852 50835852 + Missense_Mutation SNP T T G TCGA-AA-3930-01A-01W-0995-10 TCGA-AA-3930-10A-01W-0995-10 g.chr15:50835852T>G c.387A>C c.(385-387)caA>caC p.Q129H COADREAD 15 50835867 50835867 + Silent SNP C C T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr15:50835867C>T c.372G>A c.(370-372)acG>acA p.T124T COADREAD 15 50836904 50836904 + Missense_Mutation SNP A A C TCGA-AZ-4315-01A-01D-1408-10 TCGA-AZ-4315-10A-01D-1408-10 g.chr15:50836904A>C c.128T>G c.(127-129)gTc>gGc p.V43G DLBC 15 50836846 50836846 + Silent SNP G G C TCGA-G8-6324-01A-11D-2210-10 TCGA-G8-6324-10A-01D-2210-10 g.chr15:50836846G>C c.186C>G c.(184-186)ctC>ctG p.L62L ESCA 15 50792968 50792968 + 3'UTR SNP A A G TCGA-VR-AA4G-01A-11D-A37C-09 TCGA-VR-AA4G-10A-01D-A37F-09 g.chr15:50792968A>G ESCA 15 50792993 50792993 + 3'UTR SNP G G A TCGA-IG-A3Y9-01A-12D-A247-09 TCGA-IG-A3Y9-10A-01D-A247-09 g.chr15:50792993G>A ESCA 15 50793017 50793017 + 3'UTR SNP C C T TCGA-L5-A8NS-01A-12D-A37C-09 TCGA-L5-A8NS-11A-11D-A37F-09 g.chr15:50793017C>T GBM 15 50838708 50838708 + Silent SNP C C T TCGA-06-0192-01B-01W-0348-08 TCGA-06-0192-10A-01W-0348-08 g.chr15:50838708C>T c.15G>A c.(13-15)ccG>ccA p.P5P GBMLGG 15 50838708 50838708 + Silent SNP C C T TCGA-06-0192-01B-01W-0348-08 TCGA-06-0192-10A-01W-0348-08 g.chr15:50838708C>T c.15G>A c.(13-15)ccG>ccA p.P5P HNSC 15 50830917 50830917 + Silent SNP G G A TCGA-BA-5152-01A-02D-1870-08 TCGA-BA-5152-10A-01D-1870-08 g.chr15:50830917G>A c.792C>T c.(790-792)ttC>ttT p.F264F KIPAN 15 50833262 50833262 + Missense_Mutation SNP T T C TCGA-B0-5098-01A-01D-1421-08 TCGA-B0-5098-11A-01D-1421-08 g.chr15:50833262T>C c.644A>G c.(643-645)tAt>tGt p.Y215C KIPAN 15 50833303 50833303 + Silent SNP G G A TCGA-B0-5116-01A-02D-1421-08 TCGA-B0-5116-11A-01D-1421-08 g.chr15:50833303G>A c.603C>T c.(601-603)aaC>aaT p.N201N KIPAN 15 50835798 50835798 + Missense_Mutation SNP T T A TCGA-CJ-4899-01A-01D-1462-08 TCGA-CJ-4899-11A-01D-1462-08 g.chr15:50835798T>A c.441A>T c.(439-441)aaA>aaT p.K147N KIRC 15 50833262 50833262 + Missense_Mutation SNP T T C TCGA-B0-5098-01A-01D-1421-08 TCGA-B0-5098-11A-01D-1421-08 g.chr15:50833262T>C c.644A>G c.(643-645)tAt>tGt p.Y215C KIRC 15 50833303 50833303 + Silent SNP G G A TCGA-B0-5116-01A-02D-1421-08 TCGA-B0-5116-11A-01D-1421-08 g.chr15:50833303G>A c.603C>T c.(601-603)aaC>aaT p.N201N KIRC 15 50835798 50835798 + Missense_Mutation SNP T T A TCGA-CJ-4899-01A-01D-1462-08 TCGA-CJ-4899-11A-01D-1462-08 g.chr15:50835798T>A c.441A>T c.(439-441)aaA>aaT p.K147N LIHC 15 50822035 50822035 + Missense_Mutation SNP T T C TCGA-ED-A8O6-01A-11D-A35Z-10 TCGA-ED-A8O6-10A-01D-A35Z-10 g.chr15:50822035T>C c.895A>G c.(895-897)Att>Gtt p.I299V LIHC 15 50833284 50833284 + Missense_Mutation SNP A A G TCGA-DD-A1ED-01A-11D-A152-10 TCGA-DD-A1ED-10A-01D-A152-10 g.chr15:50833284A>G c.622T>C c.(622-624)Tca>Cca p.S208P LIHC 15 50833322 50833322 + Missense_Mutation SNP T T C TCGA-DD-A3A1-01A-11D-A20W-10 TCGA-DD-A3A1-11A-11D-A20W-10 g.chr15:50833322T>C c.584A>G c.(583-585)gAg>gGg p.E195G LUAD 15 50836842 50836842 + Missense_Mutation SNP T T C TCGA-17-Z011-01A-01W-0746-08 TCGA-17-Z011-11A-01W-0746-08 g.chr15:50836842T>C c.190A>G c.(190-192)Agc>Ggc p.S64G LUSC 15 50822029 50822029 + Missense_Mutation SNP G G A TCGA-22-1016-01A-01D-1521-08 TCGA-22-1016-11A-01D-1521-08 g.chr15:50822029G>A c.901C>T c.(901-903)Cgg>Tgg p.R301W LUSC 15 50833434 50833434 + Missense_Mutation SNP C C T TCGA-22-5482-01A-01D-1632-08 TCGA-22-5482-11A-01D-1632-08 g.chr15:50833434C>T c.472G>A c.(472-474)Gag>Aag p.E158K PAAD 15 50822088 50822088 + Missense_Mutation SNP G G A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr15:50822088G>A c.842C>T c.(841-843)aCg>aTg p.T281M PRAD 15 50833426 50833426 + Silent SNP T T C TCGA-EJ-7793-01A-31D-2260-08 TCGA-EJ-7793-10A-01D-2260-08 g.chr15:50833426T>C c.480A>G c.(478-480)ggA>ggG p.G160G READ 15 50831000 50831000 + Missense_Mutation SNP C C T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr15:50831000C>T c.709G>A c.(709-711)Gaa>Aaa p.E237K READ 15 50835867 50835867 + Silent SNP C C T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr15:50835867C>T c.372G>A c.(370-372)acG>acA p.T124T SARC 15 50835876 50835876 + Silent SNP T T G TCGA-KF-A41W-01A-11D-A24N-09 TCGA-KF-A41W-11A-11D-A24N-09 g.chr15:50835876T>G c.363A>C c.(361-363)ccA>ccC p.P121P SKCM 15 50830987 50830987 + Missense_Mutation SNP G G A TCGA-FS-A1ZQ-06A-11D-A197-08 TCGA-FS-A1ZQ-10A-01D-A199-08 g.chr15:50830987G>A c.722C>T c.(721-723)tCc>tTc p.S241F SKCM 15 50833252 50833252 + Silent SNP G G A TCGA-EE-A29S-06A-11D-A197-08 TCGA-EE-A29S-10A-01D-A199-08 g.chr15:50833252G>A c.654C>T c.(652-654)tcC>tcT p.S218S SKCM 15 50833302 50833302 + Missense_Mutation SNP C C T TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr15:50833302C>T c.604G>A c.(604-606)Gaa>Aaa p.E202K SKCM 15 50833406 50833406 + Missense_Mutation SNP C C G TCGA-ER-A19P-06A-11D-A196-08 TCGA-ER-A19P-10A-01D-A198-08 g.chr15:50833406C>G c.500G>C c.(499-501)aGg>aCg p.R167T

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BRCA-EU 15 50787759 50787759 single base substitution A G downstream_gene_variant BRCA-EU 15 50788714 50788714 single base substitution C T downstream_gene_variant BRCA-EU 15 50789932 50789932 single base substitution C T downstream_gene_variant BRCA-EU 15 50793707 50793707 single base substitution T C intron_variant BRCA-EU 15 50794367 50794367 single base substitution C A intron_variant BRCA-EU 15 50795756 50795756 single base substitution C T intron_variant BRCA-EU 15 50797172 50797172 single base substitution C T intron_variant BRCA-EU 15 50798955 50798955 single base substitution G A intron_variant BRCA-EU 15 50801559 50801559 single base substitution G A downstream_gene_variant BRCA-EU 15 50801559 50801559 single base substitution G A intron_variant BRCA-EU 15 50801890 50801890 single base substitution C T downstream_gene_variant BRCA-EU 15 50801890 50801890 single base substitution C T intron_variant BRCA-EU 15 50801931 50801931 deletion of <=200bp C - downstream_gene_variant BRCA-EU 15 50801931 50801931 deletion of <=200bp C - intron_variant BRCA-EU 15 50803115 50803115 single base substitution A C downstream_gene_variant BRCA-EU 15 50803115 50803115 single base substitution A C intron_variant BRCA-EU 15 50803309 50803309 single base substitution G C downstream_gene_variant BRCA-EU 15 50803309 50803309 single base substitution G C intron_variant BRCA-EU 15 50803396 50803396 single base substitution A G downstream_gene_variant BRCA-EU 15 50803396 50803396 single base substitution A G intron_variant BRCA-EU 15 50803660 50803660 single base substitution C T downstream_gene_variant BRCA-EU 15 50803660 50803660 single base substitution C T intron_variant BRCA-EU 15 50803661 50803661 single base substitution T C downstream_gene_variant BRCA-EU 15 50803661 50803661 single base substitution T C intron_variant BRCA-EU 15 50803980 50803980 single base substitution C T downstream_gene_variant BRCA-EU 15 50803980 50803980 single base substitution C T intron_variant BRCA-EU 15 50804426 50804426 single base substitution G A downstream_gene_variant BRCA-EU 15 50804426 50804426 single base substitution G A intron_variant BRCA-EU 15 50804808 50804808 single base substitution G A downstream_gene_variant BRCA-EU 15 50804808 50804808 single base substitution G A intron_variant BRCA-EU 15 50804829 50804829 single base substitution A G downstream_gene_variant BRCA-EU 15 50804829 50804829 single base substitution A G intron_variant BRCA-EU 15 50806388 50806388 single base substitution C T intron_variant BRCA-EU 15 50806840 50806840 single base substitution C A intron_variant BRCA-EU 15 50807060 50807060 single base substitution G A intron_variant BRCA-EU 15 50807794 50807794 single base substitution A C intron_variant BRCA-EU 15 50808496 50808499 deletion of <=200bp AAAC - intron_variant BRCA-EU 15 50809893 50809893 single base substitution T A intron_variant BRCA-EU 15 50810631 50810631 single base substitution A G intron_variant BRCA-EU 15 50811303 50811303 single base substitution G A intron_variant BRCA-EU 15 50811769 50811769 single base substitution G A intron_variant BRCA-EU 15 50812290 50812290 single base substitution G A intron_variant BRCA-EU 15 50812813 50812813 single base substitution C T intron_variant BRCA-EU 15 50812832 50812832 single base substitution G C intron_variant BRCA-EU 15 50814553 50814553 single base substitution A C intron_variant BRCA-EU 15 50815229 50815229 single base substitution G T intron_variant BRCA-EU 15 50815418 50815418 single base substitution C G intron_variant BRCA-EU 15 50815554 50815554 single base substitution G C intron_variant BRCA-EU 15 50816701 50816701 single base substitution C T intron_variant BRCA-EU 15 50818112 50818112 single base substitution G C intron_variant BRCA-EU 15 50819078 50819078 single base substitution C T intron_variant BRCA-EU 15 50819599 50819599 single base substitution T A intron_variant BRCA-EU 15 50820203 50820203 single base substitution C G intron_variant BRCA-EU 15 50822087 50822087 single base substitution C T 3_prime_UTR_variant BRCA-EU 15 50822087 50822087 single base substitution C T exon_variant BRCA-EU 15 50822087 50822087 single base substitution C T synonymous_variant T281T 843G>A BRCA-EU 15 50823143 50823143 insertion of <=200bp - T intron_variant BRCA-EU 15 50824644 50824644 single base substitution C T intron_variant BRCA-EU 15 50825780 50825780 insertion of <=200bp - A intron_variant BRCA-EU 15 50827989 50827989 single base substitution T G intron_variant BRCA-EU 15 50828066 50828066 deletion of <=200bp A - intron_variant BRCA-EU 15 50828786 50828786 single base substitution C T intron_variant BRCA-EU 15 50829906 50829906 single base substitution A T intron_variant BRCA-EU 15 50830865 50830865 single base substitution T G intron_variant BRCA-EU 15 50832780 50832780 deletion of <=200bp A - intron_variant BRCA-EU 15 50832780 50832780 deletion of <=200bp A - upstream_gene_variant BRCA-EU 15 50832958 50832958 single base substitution T C intron_variant BRCA-EU 15 50832958 50832958 single base substitution T C upstream_gene_variant BRCA-EU 15 50833546 50833546 insertion of <=200bp - A intron_variant BRCA-EU 15 50833546 50833546 insertion of <=200bp - A upstream_gene_variant BRCA-EU 15 50833711 50833711 deletion of <=200bp A - intron_variant BRCA-EU 15 50833711 50833711 deletion of <=200bp A - upstream_gene_variant BRCA-EU 15 50834490 50834490 single base substitution T G intron_variant BRCA-EU 15 50834490 50834490 single base substitution T G upstream_gene_variant BRCA-EU 15 50835073 50835073 single base substitution G A intron_variant BRCA-EU 15 50835073 50835073 single base substitution G A upstream_gene_variant BRCA-EU 15 50839672 50839672 single base substitution C T upstream_gene_variant BRCA-EU 15 50840252 50840252 single base substitution C A upstream_gene_variant BRCA-EU 15 50842324 50842324 single base substitution C A upstream_gene_variant BRCA-EU 15 50842487 50842487 deletion of <=200bp G - upstream_gene_variant BRCA-EU 15 50842535 50842535 single base substitution C G upstream_gene_variant BRCA-EU 15 50843530 50843530 single base substitution C G upstream_gene_variant BRCA-FR 15 50794339 50794339 single base substitution C T intron_variant BRCA-FR 15 50798955 50798955 single base substitution G A intron_variant BRCA-FR 15 50804426 50804426 single base substitution G A downstream_gene_variant BRCA-FR 15 50804426 50804426 single base substitution G A intron_variant BRCA-FR 15 50804808 50804808 single base substitution G A downstream_gene_variant BRCA-FR 15 50804808 50804808 single base substitution G A intron_variant BRCA-FR 15 50807457 50807457 single base substitution G C intron_variant BRCA-FR 15 50812832 50812832 single base substitution G C intron_variant BRCA-FR 15 50819078 50819078 single base substitution C T intron_variant BRCA-FR 15 50831821 50831821 single base substitution C T intron_variant BRCA-FR 15 50831821 50831821 single base substitution C T upstream_gene_variant BRCA-FR 15 50832388 50832388 single base substitution G T intron_variant BRCA-FR 15 50832388 50832388 single base substitution G T upstream_gene_variant BRCA-UK 15 50818887 50818887 single base substitution C G intron_variant BRCA-US 15 50831018 50831018 single base substitution C T 3_prime_UTR_variant BRCA-US 15 50831018 50831018 single base substitution C T exon_variant BRCA-US 15 50831018 50831018 single base substitution C T missense_variant A231T 691G>A BTCA-JP 15 50788116 50788116 single base substitution C A downstream_gene_variant BTCA-JP 15 50836888 50836888 single base substitution G C intron_variant BTCA-JP 15 50836888 50836888 single base substitution G C missense_variant N48K 144C>G CESC-US 15 50788052 50788052 single base substitution A C downstream_gene_variant CESC-US 15 50789248 50789248 single base substitution G A downstream_gene_variant CESC-US 15 50833424 50833424 single base substitution G C exon_variant CESC-US 15 50833424 50833424 single base substitution G C intron_variant CESC-US 15 50833424 50833424 single base substitution G C missense_variant S161C 482C>G CESC-US 15 50833424 50833424 single base substitution G C upstream_gene_variant CLLE-ES 15 50796744 50796744 single base substitution G A intron_variant CLLE-ES 15 50799178 50799178 single base substitution A T intron_variant CLLE-ES 15 50805717 50805717 single base substitution A G intron_variant CLLE-ES 15 50817853 50817853 deletion of <=200bp G - intron_variant CLLE-ES 15 50825360 50825360 single base substitution A T intron_variant CLLE-ES 15 50825461 50825461 single base substitution A G intron_variant CLLE-ES 15 50825511 50825511 single base substitution G A intron_variant CLLE-ES 15 50842485 50842485 single base substitution T G upstream_gene_variant CLLE-ES 15 50843884 50843884 single base substitution T A upstream_gene_variant COAD-US 15 50789322 50789322 single base substitution A C downstream_gene_variant COAD-US 15 50789375 50789375 deletion of <=200bp A - downstream_gene_variant COAD-US 15 50793007 50793007 single base substitution G T 3_prime_UTR_variant COAD-US 15 50793007 50793007 single base substitution G T downstream_gene_variant COAD-US 15 50793007 50793007 single base substitution G T missense_variant H322N 964C>A COCA-CN 15 50793089 50793089 single base substitution G A exon_variant COCA-CN 15 50793089 50793089 single base substitution G A intron_variant COCA-CN 15 50800095 50800095 single base substitution G A intron_variant COCA-CN 15 50805005 50805005 single base substitution A G downstream_gene_variant COCA-CN 15 50805005 50805005 single base substitution A G intron_variant COCA-CN 15 50824478 50824478 single base substitution C T intron_variant COCA-CN 15 50830967 50830967 single base substitution C A 3_prime_UTR_variant COCA-CN 15 50830967 50830967 single base substitution C A exon_variant COCA-CN 15 50830967 50830967 single base substitution C A stop_gained E248* 742G>T COCA-CN 15 50838783 50838783 single base substitution T G 5_prime_UTR_variant COCA-CN 15 50838783 50838783 single base substitution T G exon_variant EOPC-DE 15 50822466 50822466 single base substitution T C intron_variant EOPC-DE 15 50830043 50830043 single base substitution A G intron_variant ESAD-UK 15 50789587 50789587 single base substitution T C downstream_gene_variant ESAD-UK 15 50789721 50789721 single base substitution T G downstream_gene_variant ESAD-UK 15 50795520 50795520 single base substitution C T intron_variant ESAD-UK 15 50800221 50800221 single base substitution G A intron_variant ESAD-UK 15 50800611 50800611 single base substitution C T downstream_gene_variant ESAD-UK 15 50800611 50800611 single base substitution C T intron_variant ESAD-UK 15 50802655 50802655 insertion of <=200bp - A downstream_gene_variant ESAD-UK 15 50802655 50802655 insertion of <=200bp - A intron_variant ESAD-UK 15 50802681 50802681 single base substitution C A downstream_gene_variant ESAD-UK 15 50802681 50802681 single base substitution C A intron_variant ESAD-UK 15 50803361 50803361 single base substitution T G downstream_gene_variant ESAD-UK 15 50803361 50803361 single base substitution T G intron_variant ESAD-UK 15 50805404 50805404 single base substitution A C downstream_gene_variant ESAD-UK 15 50805404 50805404 single base substitution A C intron_variant ESAD-UK 15 50805514 50805514 single base substitution A T downstream_gene_variant ESAD-UK 15 50805514 50805514 single base substitution A T intron_variant ESAD-UK 15 50806933 50806933 single base substitution G T intron_variant ESAD-UK 15 50807183 50807183 insertion of <=200bp - ACAC intron_variant ESAD-UK 15 50807540 50807540 single base substitution G A intron_variant ESAD-UK 15 50808217 50808217 single base substitution G C intron_variant ESAD-UK 15 50808536 50808536 single base substitution C T intron_variant ESAD-UK 15 50812823 50812823 deletion of <=200bp A - intron_variant ESAD-UK 15 50814336 50814336 single base substitution G A intron_variant ESAD-UK 15 50816323 50816323 single base substitution A G intron_variant ESAD-UK 15 50816711 50816711 single base substitution A G intron_variant ESAD-UK 15 50817609 50817609 deletion of <=200bp A - intron_variant ESAD-UK 15 50819387 50819387 single base substitution G A intron_variant ESAD-UK 15 50823617 50823617 single base substitution A G intron_variant ESAD-UK 15 50823871 50823871 single base substitution G C intron_variant ESAD-UK 15 50824158 50824158 deletion of <=200bp C - intron_variant ESAD-UK 15 50824713 50824713 single base substitution C T intron_variant ESAD-UK 15 50825675 50825675 deletion of <=200bp A - intron_variant ESAD-UK 15 50825675 50825675 single base substitution A G intron_variant ESAD-UK 15 50825862 50825862 single base substitution A C intron_variant ESAD-UK 15 50827948 50827948 insertion of <=200bp - A intron_variant ESAD-UK 15 50828019 50828019 single base substitution C G intron_variant ESAD-UK 15 50829333 50829333 single base substitution A C intron_variant ESAD-UK 15 50829543 50829543 single base substitution T C intron_variant ESAD-UK 15 50829836 50829836 single base substitution G A intron_variant ESAD-UK 15 50831315 50831315 single base substitution T G intron_variant ESAD-UK 15 50831315 50831315 single base substitution T G upstream_gene_variant ESAD-UK 15 50833131 50833131 single base substitution T A intron_variant ESAD-UK 15 50833131 50833131 single base substitution T A upstream_gene_variant ESAD-UK 15 50833155 50833155 single base substitution C G intron_variant ESAD-UK 15 50833155 50833155 single base substitution C G upstream_gene_variant ESAD-UK 15 50838351 50838351 single base substitution G A intron_variant ESAD-UK 15 50838452 50838452 single base substitution C G intron_variant ESAD-UK 15 50838733 50838733 single base substitution C T 5_prime_UTR_variant ESAD-UK 15 50838733 50838733 single base substitution C T exon_variant ESAD-UK 15 50839438 50839438 single base substitution T A upstream_gene_variant ESAD-UK 15 50841443 50841443 single base substitution G A upstream_gene_variant ESAD-UK 15 50843241 50843241 single base substitution G T upstream_gene_variant ESAD-UK 15 50843642 50843642 single base substitution C T upstream_gene_variant GBM-US 15 50788098 50788098 single base substitution T C downstream_gene_variant GBM-US 15 50838708 50838708 single base substitution C T exon_variant GBM-US 15 50838708 50838708 single base substitution C T synonymous_variant P5P 15G>A KIRC-US 15 50791105 50791105 single base substitution C G downstream_gene_variant KIRC-US 15 50833303 50833303 single base substitution G A 3_prime_UTR_variant KIRC-US 15 50833303 50833303 single base substitution G A intron_variant KIRC-US 15 50833303 50833303 single base substitution G A synonymous_variant N201N 603C>T KIRC-US 15 50833303 50833303 single base substitution G A upstream_gene_variant KIRC-US 15 50835798 50835798 single base substitution T A intron_variant KIRC-US 15 50835798 50835798 single base substitution T A missense_variant K147N 441A>T KIRC-US 15 50835798 50835798 single base substitution T A upstream_gene_variant KIRP-US 15 50835960 50835960 single base substitution G A intron_variant KIRP-US 15 50835960 50835960 single base substitution G A synonymous_variant A93A 279C>T KIRP-US 15 50835960 50835960 single base substitution G A upstream_gene_variant LAML-KR 15 50810436 50810436 single base substitution G T intron_variant LAML-KR 15 50811258 50811258 single base substitution C T intron_variant LAML-KR 15 50822277 50822277 single base substitution A G intron_variant LICA-CN 15 50830990 50830990 single base substitution C A 3_prime_UTR_variant LICA-CN 15 50830990 50830990 single base substitution C A exon_variant LICA-CN 15 50830990 50830990 single base substitution C A missense_variant C240F 719G>T LICA-FR 15 50793033 50793033 deletion of <=200bp T - downstream_gene_variant LICA-FR 15 50793033 50793033 deletion of <=200bp T - frameshift_variant N313 LICA-FR 15 50793033 50793033 deletion of <=200bp T - splice_region_variant LICA-FR 15 50813774 50813774 single base substitution A G intron_variant LICA-FR 15 50817753 50817753 single base substitution G A intron_variant LICA-FR 15 50817759 50817759 single base substitution A G intron_variant LICA-FR 15 50820263 50820267 deletion of <=200bp TTTTT - intron_variant LICA-FR 15 50828745 50828745 single base substitution G A intron_variant LICA-FR 15 50835801 50835801 single base substitution T C intron_variant LICA-FR 15 50835801 50835801 single base substitution T C synonymous_variant L146L 438A>G LICA-FR 15 50835801 50835801 single base substitution T C upstream_gene_variant LICA-FR 15 50842519 50842519 single base substitution T C upstream_gene_variant LICA-FR 15 50843145 50843145 single base substitution G C upstream_gene_variant LINC-JP 15 50790976 50790976 single base substitution A G downstream_gene_variant LINC-JP 15 50802830 50802830 single base substitution A C downstream_gene_variant LINC-JP 15 50802830 50802830 single base substitution A C intron_variant LINC-JP 15 50803993 50803993 single base substitution A T downstream_gene_variant LINC-JP 15 50803993 50803993 single base substitution A T intron_variant LINC-JP 15 50820263 50820268 deletion of <=200bp TTTTTT - intron_variant LINC-JP 15 50830508 50830508 single base substitution G A intron_variant LINC-JP 15 50833526 50833526 single base substitution T C intron_variant LINC-JP 15 50833526 50833526 single base substitution T C upstream_gene_variant LINC-JP 15 50836894 50836894 single base substitution C A intron_variant LINC-JP 15 50836894 50836894 single base substitution C A missense_variant L46F 138G>T LINC-JP 15 50839932 50839932 single base substitution C A upstream_gene_variant LINC-JP 15 50840403 50840403 single base substitution A G upstream_gene_variant LINC-JP 15 50843498 50843498 single base substitution A G upstream_gene_variant LIRI-JP 15 50791761 50791761 single base substitution T G downstream_gene_variant LIRI-JP 15 50793356 50793373 deletion of <=200bp ACAATAAGAAGATAATTC - intron_variant LIRI-JP 15 50793734 50793734 single base substitution A G intron_variant LIRI-JP 15 50794072 50794072 single base substitution A G intron_variant LIRI-JP 15 50797804 50797804 single base substitution A G intron_variant LIRI-JP 15 50799524 50799524 single base substitution A G intron_variant LIRI-JP 15 50806212 50806212 single base substitution A C intron_variant LIRI-JP 15 50807354 50807354 single base substitution A G intron_variant LIRI-JP 15 50810226 50810226 single base substitution T C intron_variant LIRI-JP 15 50812867 50812867 single base substitution T A intron_variant LIRI-JP 15 50820384 50820384 single base substitution G A intron_variant LIRI-JP 15 50822414 50822414 single base substitution A C intron_variant LIRI-JP 15 50823731 50823731 single base substitution G T intron_variant LIRI-JP 15 50831225 50831225 single base substitution C T intron_variant LIRI-JP 15 50831225 50831225 single base substitution C T upstream_gene_variant LIRI-JP 15 50832510 50832510 single base substitution T G intron_variant LIRI-JP 15 50832510 50832510 single base substitution T G upstream_gene_variant LIRI-JP 15 50832985 50832985 single base substitution T C intron_variant LIRI-JP 15 50832985 50832985 single base substitution T C upstream_gene_variant LIRI-JP 15 50834966 50834966 single base substitution G A intron_variant LIRI-JP 15 50834966 50834966 single base substitution G A upstream_gene_variant LIRI-JP 15 50835291 50835291 single base substitution G C intron_variant LIRI-JP 15 50835291 50835291 single base substitution G C upstream_gene_variant LIRI-JP 15 50836430 50836430 single base substitution G A intron_variant LIRI-JP 15 50836886 50836886 insertion of <=200bp - A frameshift_variant L49F? LIRI-JP 15 50836886 50836886 insertion of <=200bp - A intron_variant LIRI-JP 15 50837523 50837523 single base substitution G A intron_variant LIRI-JP 15 50838460 50838460 single base substitution T C intron_variant LIRI-JP 15 50838710 50838710 single base substitution G T exon_variant LIRI-JP 15 50838710 50838710 single base substitution G T missense_variant P5T 13C>A LIRI-JP 15 50838839 50838840 deletion of <=200bp CT - 5_prime_UTR_variant LIRI-JP 15 50838839 50838840 deletion of <=200bp CT - exon_variant LIRI-JP 15 50843199 50843199 single base substitution G A upstream_gene_variant LUSC-KR 15 50801023 50801023 single base substitution C A downstream_gene_variant LUSC-KR 15 50801023 50801023 single base substitution C A intron_variant LUSC-KR 15 50810702 50810702 single base substitution C T intron_variant LUSC-KR 15 50812820 50812820 single base substitution G A intron_variant LUSC-KR 15 50812863 50812863 single base substitution C T intron_variant LUSC-KR 15 50813567 50813567 single base substitution T G intron_variant LUSC-KR 15 50820815 50820815 single base substitution C A intron_variant LUSC-KR 15 50824979 50824979 single base substitution G A intron_variant LUSC-KR 15 50835947 50835947 single base substitution C T intron_variant LUSC-KR 15 50835947 50835947 single base substitution C T missense_variant D98N 292G>A LUSC-KR 15 50835947 50835947 single base substitution C T upstream_gene_variant LUSC-KR 15 50836035 50836035 single base substitution G C intron_variant LUSC-KR 15 50842000 50842000 single base substitution A G upstream_gene_variant LUSC-US 15 50822029 50822029 single base substitution G A 3_prime_UTR_variant LUSC-US 15 50822029 50822029 single base substitution G A exon_variant LUSC-US 15 50822029 50822029 single base substitution G A missense_variant R301W 901C>T LUSC-US 15 50833434 50833434 single base substitution C T exon_variant LUSC-US 15 50833434 50833434 single base substitution C T intron_variant LUSC-US 15 50833434 50833434 single base substitution C T missense_variant E158K 472G>A LUSC-US 15 50833434 50833434 single base substitution C T upstream_gene_variant MALY-DE 15 50801015 50801015 single base substitution C A downstream_gene_variant MALY-DE 15 50801015 50801015 single base substitution C A intron_variant MALY-DE 15 50802955 50802955 single base substitution A G downstream_gene_variant MALY-DE 15 50802955 50802955 single base substitution A G intron_variant MALY-DE 15 50803943 50803943 single base substitution C T downstream_gene_variant MALY-DE 15 50803943 50803943 single base substitution C T intron_variant MALY-DE 15 50806585 50806585 single base substitution A C intron_variant MALY-DE 15 50807850 50807851 deletion of <=200bp TA - intron_variant MALY-DE 15 50811456 50811456 single base substitution C G intron_variant MALY-DE 15 50811738 50811738 single base substitution C T intron_variant MALY-DE 15 50811739 50811739 single base substitution G A intron_variant MALY-DE 15 50811862 50811862 single base substitution A G intron_variant MALY-DE 15 50813703 50813703 single base substitution G A intron_variant MALY-DE 15 50817735 50817735 single base substitution G A intron_variant MALY-DE 15 50817803 50817803 single base substitution G A intron_variant MALY-DE 15 50817805 50817805 single base substitution A G intron_variant MALY-DE 15 50817831 50817831 single base substitution A G intron_variant MALY-DE 15 50817833 50817833 single base substitution G A intron_variant MALY-DE 15 50817841 50817841 single base substitution G A intron_variant MALY-DE 15 50819569 50819569 insertion of <=200bp - T intron_variant MALY-DE 15 50825675 50825675 deletion of <=200bp A - intron_variant MALY-DE 15 50827955 50827955 single base substitution T A intron_variant MALY-DE 15 50837892 50837893 deletion of <=200bp AC - intron_variant MALY-DE 15 50839091 50839091 single base substitution C G upstream_gene_variant MALY-DE 15 50840488 50840488 single base substitution G A upstream_gene_variant MALY-DE 15 50842475 50842475 single base substitution T C upstream_gene_variant MELA-AU 15 50787834 50787834 single base substitution C T downstream_gene_variant MELA-AU 15 50789056 50789056 single base substitution C T downstream_gene_variant MELA-AU 15 50789116 50789116 single base substitution C T downstream_gene_variant MELA-AU 15 50789895 50789895 single base substitution C T downstream_gene_variant MELA-AU 15 50790317 50790317 single base substitution C T downstream_gene_variant MELA-AU 15 50790657 50790657 single base substitution C T downstream_gene_variant MELA-AU 15 50790683 50790683 single base substitution T G downstream_gene_variant MELA-AU 15 50790924 50790924 single base substitution C T downstream_gene_variant MELA-AU 15 50791491 50791491 single base substitution A T downstream_gene_variant MELA-AU 15 50791499 50791499 single base substitution C G downstream_gene_variant MELA-AU 15 50791537 50791537 deletion of <=200bp T - downstream_gene_variant MELA-AU 15 50791585 50791585 single base substitution C T downstream_gene_variant MELA-AU 15 50794051 50794051 single base substitution C A intron_variant MELA-AU 15 50794109 50794109 single base substitution C T intron_variant MELA-AU 15 50794139 50794139 single base substitution C A intron_variant MELA-AU 15 50794208 50794208 single base substitution C T intron_variant MELA-AU 15 50794333 50794333 single base substitution C T intron_variant MELA-AU 15 50794403 50794403 single base substitution C T intron_variant MELA-AU 15 50794883 50794883 single base substitution C T intron_variant MELA-AU 15 50794952 50794952 single base substitution C T intron_variant MELA-AU 15 50794987 50794987 single base substitution G A intron_variant MELA-AU 15 50796279 50796279 single base substitution G A intron_variant MELA-AU 15 50796530 50796530 single base substitution C T intron_variant MELA-AU 15 50797865 50797865 single base substitution T A intron_variant MELA-AU 15 50798185 50798185 single base substitution T A intron_variant MELA-AU 15 50798749 50798749 single base substitution G A intron_variant MELA-AU 15 50798941 50798941 single base substitution G A intron_variant MELA-AU 15 50799750 50799750 single base substitution C T intron_variant MELA-AU 15 50799761 50799761 single base substitution T C intron_variant MELA-AU 15 50800721 50800721 single base substitution G A downstream_gene_variant MELA-AU 15 50800721 50800721 single base substitution G A intron_variant MELA-AU 15 50800942 50800942 single base substitution C T downstream_gene_variant MELA-AU 15 50800942 50800942 single base substitution C T intron_variant MELA-AU 15 50801658 50801658 single base substitution C T downstream_gene_variant MELA-AU 15 50801658 50801658 single base substitution C T intron_variant MELA-AU 15 50801781 50801781 single base substitution C T downstream_gene_variant MELA-AU 15 50801781 50801781 single base substitution C T intron_variant MELA-AU 15 50801813 50801813 single base substitution C T downstream_gene_variant MELA-AU 15 50801813 50801813 single base substitution C T intron_variant MELA-AU 15 50802059 50802059 single base substitution T G downstream_gene_variant MELA-AU 15 50802059 50802059 single base substitution T G intron_variant MELA-AU 15 50802193 50802193 single base substitution C T downstream_gene_variant MELA-AU 15 50802193 50802193 single base substitution C T intron_variant MELA-AU 15 50802540 50802540 single base substitution G A downstream_gene_variant MELA-AU 15 50802540 50802540 single base substitution G A intron_variant MELA-AU 15 50804372 50804372 single base substitution C T downstream_gene_variant MELA-AU 15 50804372 50804372 single base substitution C T intron_variant MELA-AU 15 50804422 50804422 single base substitution G A downstream_gene_variant MELA-AU 15 50804422 50804422 single base substitution G A intron_variant MELA-AU 15 50804484 50804484 single base substitution C T downstream_gene_variant MELA-AU 15 50804484 50804484 single base substitution C T intron_variant MELA-AU 15 50804494 50804494 single base substitution C T downstream_gene_variant MELA-AU 15 50804494 50804494 single base substitution C T intron_variant MELA-AU 15 50805140 50805140 single base substitution C T downstream_gene_variant MELA-AU 15 50805140 50805140 single base substitution C T intron_variant MELA-AU 15 50805190 50805190 single base substitution C T downstream_gene_variant MELA-AU 15 50805190 50805190 single base substitution C T intron_variant MELA-AU 15 50806760 50806760 single base substitution C T intron_variant MELA-AU 15 50806960 50806960 single base substitution C T intron_variant MELA-AU 15 50807940 50807940 deletion of <=200bp A - intron_variant MELA-AU 15 50808054 50808054 single base substitution T C intron_variant MELA-AU 15 50808640 50808640 single base substitution C T intron_variant MELA-AU 15 50808751 50808751 single base substitution T C intron_variant MELA-AU 15 50809245 50809245 single base substitution C T intron_variant MELA-AU 15 50809253 50809253 single base substitution C T intron_variant MELA-AU 15 50809465 50809465 single base substitution C G intron_variant MELA-AU 15 50809762 50809762 single base substitution G A intron_variant MELA-AU 15 50809769 50809769 single base substitution C T intron_variant MELA-AU 15 50810399 50810399 single base substitution G A intron_variant MELA-AU 15 50810839 50810839 single base substitution T A intron_variant MELA-AU 15 50810920 50810920 single base substitution A T intron_variant MELA-AU 15 50810952 50810952 single base substitution G A intron_variant MELA-AU 15 50810960 50810960 single base substitution G A intron_variant MELA-AU 15 50811127 50811127 single base substitution T A intron_variant MELA-AU 15 50811403 50811403 single base substitution G A intron_variant MELA-AU 15 50811827 50811827 single base substitution G A intron_variant MELA-AU 15 50812007 50812007 single base substitution G A intron_variant MELA-AU 15 50812400 50812400 single base substitution G A intron_variant MELA-AU 15 50812725 50812725 single base substitution G A intron_variant MELA-AU 15 50813047 50813047 single base substitution C T intron_variant MELA-AU 15 50813622 50813622 single base substitution A G intron_variant MELA-AU 15 50813869 50813869 single base substitution C T intron_variant MELA-AU 15 50814739 50814739 single base substitution C T intron_variant MELA-AU 15 50814802 50814802 single base substitution G A intron_variant MELA-AU 15 50815144 50815144 single base substitution C T intron_variant MELA-AU 15 50815890 50815890 single base substitution A T intron_variant MELA-AU 15 50816524 50816524 single base substitution G A intron_variant MELA-AU 15 50816602 50816602 single base substitution G A intron_variant MELA-AU 15 50816757 50816757 single base substitution A T intron_variant MELA-AU 15 50817237 50817237 single base substitution T G intron_variant MELA-AU 15 50817299 50817299 single base substitution G A intron_variant MELA-AU 15 50817667 50817667 single base substitution G A intron_variant MELA-AU 15 50817753 50817753 single base substitution G A intron_variant MELA-AU 15 50817759 50817759 single base substitution A G intron_variant MELA-AU 15 50817763 50817763 single base substitution A G intron_variant MELA-AU 15 50817791 50817791 single base substitution A G intron_variant MELA-AU 15 50817898 50817898 single base substitution A G intron_variant MELA-AU 15 50818200 50818200 single base substitution G A intron_variant MELA-AU 15 50818604 50818604 single base substitution C T intron_variant MELA-AU 15 50818652 50818652 single base substitution C T intron_variant MELA-AU 15 50819093 50819093 single base substitution G A intron_variant MELA-AU 15 50819535 50819535 single base substitution G A intron_variant MELA-AU 15 50819974 50819974 single base substitution G A intron_variant MELA-AU 15 50820031 50820031 single base substitution A G intron_variant MELA-AU 15 50820033 50820033 single base substitution C T intron_variant MELA-AU 15 50820609 50820609 single base substitution A G intron_variant MELA-AU 15 50820627 50820627 single base substitution G A intron_variant MELA-AU 15 50821861 50821861 single base substitution G A intron_variant MELA-AU 15 50822273 50822273 single base substitution G A intron_variant MELA-AU 15 50822288 50822288 single base substitution G A intron_variant MELA-AU 15 50822490 50822490 single base substitution G A intron_variant MELA-AU 15 50822508 50822508 single base substitution G A intron_variant MELA-AU 15 50822768 50822768 single base substitution G A intron_variant MELA-AU 15 50822970 50822970 single base substitution G A intron_variant MELA-AU 15 50823377 50823377 single base substitution G A intron_variant MELA-AU 15 50823696 50823696 single base substitution G A intron_variant MELA-AU 15 50824277 50824277 single base substitution T G 3_prime_UTR_variant MELA-AU 15 50824277 50824277 single base substitution T G intron_variant MELA-AU 15 50824349 50824349 single base substitution A C exon_variant MELA-AU 15 50824349 50824349 single base substitution A C intron_variant MELA-AU 15 50824394 50824394 single base substitution G A exon_variant MELA-AU 15 50824394 50824394 single base substitution G A intron_variant MELA-AU 15 50825220 50825221 multiple base substitution (>=2bp and <=200bp) CC AT intron_variant MELA-AU 15 50825294 50825294 single base substitution G A intron_variant MELA-AU 15 50825347 50825347 single base substitution C T intron_variant MELA-AU 15 50825753 50825753 single base substitution G A intron_variant MELA-AU 15 50826012 50826012 single base substitution A G intron_variant MELA-AU 15 50826196 50826196 single base substitution C A intron_variant MELA-AU 15 50826360 50826360 single base substitution G A intron_variant MELA-AU 15 50826938 50826938 single base substitution G A intron_variant MELA-AU 15 50826967 50826967 single base substitution G A intron_variant MELA-AU 15 50826975 50826975 single base substitution G A intron_variant MELA-AU 15 50827813 50827813 single base substitution A G intron_variant MELA-AU 15 50828038 50828038 single base substitution G A intron_variant MELA-AU 15 50828047 50828047 single base substitution C T intron_variant MELA-AU 15 50828065 50828065 single base substitution G A intron_variant MELA-AU 15 50828230 50828230 single base substitution G A intron_variant MELA-AU 15 50828276 50828276 single base substitution G A intron_variant MELA-AU 15 50828366 50828366 single base substitution G A intron_variant MELA-AU 15 50828367 50828367 single base substitution G A intron_variant MELA-AU 15 50828406 50828406 single base substitution G A intron_variant MELA-AU 15 50828484 50828484 single base substitution G A intron_variant MELA-AU 15 50828694 50828694 single base substitution C T intron_variant MELA-AU 15 50829127 50829127 single base substitution G A intron_variant MELA-AU 15 50829379 50829379 single base substitution G T intron_variant MELA-AU 15 50829423 50829423 single base substitution G A intron_variant MELA-AU 15 50829455 50829455 single base substitution A G intron_variant MELA-AU 15 50830285 50830285 single base substitution A G intron_variant MELA-AU 15 50830348 50830348 single base substitution C T intron_variant MELA-AU 15 50830913 50830914 multiple base substitution (>=2bp and <=200bp) GG AA 3_prime_UTR_variant MELA-AU 15 50830913 50830914 multiple base substitution (>=2bp and <=200bp) GG AA exon_variant MELA-AU 15 50830913 50830914 multiple base substitution (>=2bp and <=200bp) GG AA synonymous_variant HL265 MELA-AU 15 50831057 50831057 single base substitution G A intron_variant MELA-AU 15 50831057 50831057 single base substitution G A upstream_gene_variant MELA-AU 15 50831065 50831065 single base substitution G C intron_variant MELA-AU 15 50831065 50831065 single base substitution G C upstream_gene_variant MELA-AU 15 50831258 50831258 single base substitution G A intron_variant MELA-AU 15 50831258 50831258 single base substitution G A upstream_gene_variant MELA-AU 15 50831833 50831833 single base substitution G A intron_variant MELA-AU 15 50831833 50831833 single base substitution G A upstream_gene_variant MELA-AU 15 50832342 50832342 single base substitution G A intron_variant MELA-AU 15 50832342 50832342 single base substitution G A upstream_gene_variant MELA-AU 15 50833204 50833204 single base substitution G A intron_variant MELA-AU 15 50833204 50833204 single base substitution G A upstream_gene_variant MELA-AU 15 50833246 50833246 single base substitution C T intron_variant MELA-AU 15 50833246 50833246 single base substitution C T splice_region_variant MELA-AU 15 50833246 50833246 single base substitution C T upstream_gene_variant MELA-AU 15 50833744 50833744 single base substitution G A intron_variant MELA-AU 15 50833744 50833744 single base substitution G A upstream_gene_variant MELA-AU 15 50833846 50833846 single base substitution G A intron_variant MELA-AU 15 50833846 50833846 single base substitution G A upstream_gene_variant MELA-AU 15 50834205 50834205 single base substitution G A intron_variant MELA-AU 15 50834205 50834205 single base substitution G A upstream_gene_variant MELA-AU 15 50834379 50834379 single base substitution T C intron_variant MELA-AU 15 50834379 50834379 single base substitution T C upstream_gene_variant MELA-AU 15 50836061 50836061 single base substitution G A intron_variant MELA-AU 15 50836241 50836241 single base substitution G A intron_variant MELA-AU 15 50836484 50836484 single base substitution G A intron_variant MELA-AU 15 50836606 50836606 single base substitution A C intron_variant MELA-AU 15 50837127 50837127 single base substitution G A intron_variant MELA-AU 15 50837434 50837434 single base substitution A T intron_variant MELA-AU 15 50837748 50837748 single base substitution G A intron_variant MELA-AU 15 50837786 50837786 single base substitution G A intron_variant MELA-AU 15 50838153 50838153 single base substitution C T intron_variant MELA-AU 15 50838417 50838417 single base substitution G A intron_variant MELA-AU 15 50838567 50838567 single base substitution C T intron_variant MELA-AU 15 50838721 50838721 single base substitution A T exon_variant MELA-AU 15 50838721 50838721 single base substitution A T start_lost M1K 2T>A MELA-AU 15 50838730 50838730 single base substitution G A 5_prime_UTR_variant MELA-AU 15 50838730 50838730 single base substitution G A exon_variant MELA-AU 15 50838750 50838750 single base substitution T C 5_prime_UTR_variant MELA-AU 15 50838750 50838750 single base substitution T C exon_variant MELA-AU 15 50839424 50839424 single base substitution G A upstream_gene_variant MELA-AU 15 50839549 50839549 single base substitution G A upstream_gene_variant MELA-AU 15 50839657 50839657 single base substitution A T upstream_gene_variant MELA-AU 15 50840269 50840269 single base substitution G A upstream_gene_variant MELA-AU 15 50842385 50842385 single base substitution T G upstream_gene_variant MELA-AU 15 50842495 50842495 single base substitution G A upstream_gene_variant MELA-AU 15 50842797 50842797 single base substitution G A upstream_gene_variant MELA-AU 15 50843839 50843839 single base substitution G A upstream_gene_variant ORCA-IN 15 50827362 50827363 deletion of <=200bp AA - intron_variant ORCA-IN 15 50827720 50827720 single base substitution T A intron_variant ORCA-IN 15 50834678 50834678 deletion of <=200bp A - intron_variant ORCA-IN 15 50834678 50834678 deletion of <=200bp A - upstream_gene_variant OV-AU 15 50791846 50791846 single base substitution T G downstream_gene_variant OV-AU 15 50805520 50805520 single base substitution T C downstream_gene_variant OV-AU 15 50805520 50805520 single base substitution T C intron_variant OV-AU 15 50813253 50813253 single base substitution T C intron_variant OV-AU 15 50817299 50817299 single base substitution G A intron_variant OV-AU 15 50817781 50817781 single base substitution A G intron_variant OV-AU 15 50817783 50817783 single base substitution G A intron_variant OV-AU 15 50820100 50820100 single base substitution C T intron_variant OV-AU 15 50828942 50828942 single base substitution G A intron_variant OV-AU 15 50831463 50831463 single base substitution G T intron_variant OV-AU 15 50831463 50831463 single base substitution G T upstream_gene_variant OV-AU 15 50831762 50831762 single base substitution G A intron_variant OV-AU 15 50831762 50831762 single base substitution G A upstream_gene_variant OV-AU 15 50833063 50833063 single base substitution C T intron_variant OV-AU 15 50833063 50833063 single base substitution C T upstream_gene_variant OV-AU 15 50842872 50842872 single base substitution G T upstream_gene_variant PACA-AU 15 50799099 50799099 single base substitution G A intron_variant PACA-AU 15 50807037 50807037 single base substitution T A intron_variant PACA-AU 15 50807038 50807038 single base substitution A T intron_variant PACA-AU 15 50809874 50809874 single base substitution C A intron_variant PACA-AU 15 50817898 50817898 single base substitution A G intron_variant PACA-AU 15 50818637 50818637 single base substitution G A intron_variant PACA-AU 15 50819725 50819725 single base substitution A C intron_variant PACA-AU 15 50824093 50824093 single base substitution C T intron_variant PACA-AU 15 50825675 50825675 deletion of <=200bp A - intron_variant PACA-AU 15 50832300 50832300 single base substitution G A intron_variant PACA-AU 15 50832300 50832300 single base substitution G A upstream_gene_variant PACA-AU 15 50837458 50837458 single base substitution A C intron_variant PACA-AU 15 50838544 50838544 single base substitution C T intron_variant PACA-CA 15 50794198 50794198 single base substitution C A intron_variant PACA-CA 15 50798195 50798195 single base substitution G C intron_variant PACA-CA 15 50800095 50800095 single base substitution G A intron_variant PACA-CA 15 50805624 50805624 single base substitution C T 3_prime_UTR_variant PACA-CA 15 50805624 50805624 single base substitution C T intron_variant PACA-CA 15 50805950 50805950 single base substitution C T intron_variant PACA-CA 15 50813191 50813191 single base substitution A G intron_variant PACA-CA 15 50818415 50818415 single base substitution T G intron_variant PACA-CA 15 50818932 50818932 single base substitution C T intron_variant PACA-CA 15 50822019 50822019 single base substitution G C 3_prime_UTR_variant PACA-CA 15 50822019 50822019 single base substitution G C exon_variant PACA-CA 15 50822019 50822019 single base substitution G C missense_variant P304R 911C>G PACA-CA 15 50822147 50822147 single base substitution T G intron_variant PACA-CA 15 50824720 50824720 single base substitution G A intron_variant PACA-CA 15 50825675 50825675 deletion of <=200bp A - intron_variant PACA-CA 15 50825714 50825714 single base substitution A C intron_variant PACA-CA 15 50828057 50828057 single base substitution G A intron_variant PACA-CA 15 50828602 50828602 single base substitution C G intron_variant PACA-CA 15 50829614 50829614 single base substitution A G intron_variant PACA-CA 15 50832074 50832074 single base substitution C G intron_variant PACA-CA 15 50832074 50832074 single base substitution C G upstream_gene_variant PACA-CA 15 50834671 50834671 single base substitution C T intron_variant PACA-CA 15 50834671 50834671 single base substitution C T upstream_gene_variant PACA-CA 15 50834678 50834678 single base substitution A T intron_variant PACA-CA 15 50834678 50834678 single base substitution A T upstream_gene_variant PACA-CA 15 50834966 50834966 single base substitution G A intron_variant PACA-CA 15 50834966 50834966 single base substitution G A upstream_gene_variant PACA-CA 15 50840170 50840170 single base substitution A G upstream_gene_variant PACA-CA 15 50840786 50840786 single base substitution A G upstream_gene_variant PACA-CA 15 50840837 50840837 single base substitution T C upstream_gene_variant PAEN-AU 15 50819441 50819441 single base substitution A G intron_variant PAEN-IT 15 50801159 50801159 single base substitution A G downstream_gene_variant PAEN-IT 15 50801159 50801159 single base substitution A G intron_variant PAEN-IT 15 50839902 50839902 single base substitution C T upstream_gene_variant PBCA-DE 15 50788701 50788701 single base substitution T G downstream_gene_variant PBCA-DE 15 50805694 50805694 single base substitution C T 3_prime_UTR_variant PBCA-DE 15 50805694 50805694 single base substitution C T intron_variant PBCA-DE 15 50806733 50806733 insertion of <=200bp - T intron_variant PBCA-DE 15 50808853 50808853 single base substitution C T intron_variant PBCA-DE 15 50820858 50820858 single base substitution G T intron_variant PBCA-DE 15 50821056 50821056 single base substitution A G intron_variant PBCA-DE 15 50838708 50838708 single base substitution C T exon_variant PBCA-DE 15 50838708 50838708 single base substitution C T synonymous_variant P5P 15G>A PBCA-DE 15 50839108 50839108 single base substitution C A upstream_gene_variant PBCA-DE 15 50839955 50839955 deletion of <=200bp A - upstream_gene_variant PRAD-CA 15 50795821 50795821 single base substitution G T intron_variant PRAD-CA 15 50823417 50823417 single base substitution T A intron_variant PRAD-UK 15 50791357 50791357 single base substitution T C downstream_gene_variant PRAD-UK 15 50798906 50798906 single base substitution C T intron_variant PRAD-UK 15 50799814 50799814 single base substitution A G intron_variant PRAD-UK 15 50806654 50806654 single base substitution A T intron_variant PRAD-UK 15 50815169 50815169 single base substitution T C intron_variant PRAD-UK 15 50817854 50817854 insertion of <=200bp - TATATGTATATATGTATATATGTATAT intron_variant PRAD-US 15 50788105 50788105 single base substitution G T downstream_gene_variant PRAD-US 15 50790907 50790907 single base substitution T C downstream_gene_variant PRAD-US 15 50833426 50833426 single base substitution T C exon_variant PRAD-US 15 50833426 50833426 single base substitution T C intron_variant PRAD-US 15 50833426 50833426 single base substitution T C synonymous_variant G160G 480A>G PRAD-US 15 50833426 50833426 single base substitution T C upstream_gene_variant RECA-EU 15 50804903 50804903 single base substitution C A downstream_gene_variant RECA-EU 15 50804903 50804903 single base substitution C A intron_variant RECA-EU 15 50812031 50812031 single base substitution G C intron_variant RECA-EU 15 50822383 50822383 single base substitution G C intron_variant RECA-EU 15 50833593 50833593 single base substitution C T intron_variant RECA-EU 15 50833593 50833593 single base substitution C T upstream_gene_variant RECA-EU 15 50842395 50842395 single base substitution G T upstream_gene_variant SKCA-BR 15 50788603 50788603 single base substitution T G downstream_gene_variant SKCA-BR 15 50788966 50788966 single base substitution A G downstream_gene_variant SKCA-BR 15 50789408 50789408 single base substitution G A downstream_gene_variant SKCA-BR 15 50799121 50799121 single base substitution T C intron_variant SKCA-BR 15 50810961 50810961 single base substitution G A intron_variant SKCA-BR 15 50812811 50812811 single base substitution C T intron_variant SKCA-BR 15 50813758 50813758 single base substitution G A intron_variant SKCA-BR 15 50814545 50814545 single base substitution C T intron_variant SKCA-BR 15 50814776 50814776 single base substitution G A intron_variant SKCA-BR 15 50816403 50816403 single base substitution C T intron_variant SKCA-BR 15 50817747 50817751 deletion of <=200bp ATATG - intron_variant SKCA-BR 15 50817763 50817763 single base substitution A G intron_variant SKCA-BR 15 50817765 50817769 deletion of <=200bp ATATG - intron_variant SKCA-BR 15 50817817 50817817 single base substitution A G intron_variant SKCA-BR 15 50817819 50817819 single base substitution G A intron_variant SKCA-BR 15 50818006 50818006 single base substitution T A intron_variant SKCA-BR 15 50818008 50818011 deletion of <=200bp AATG - intron_variant SKCA-BR 15 50820477 50820477 insertion of <=200bp - CTT intron_variant SKCA-BR 15 50825028 50825028 single base substitution C T intron_variant SKCA-BR 15 50827448 50827448 single base substitution C T intron_variant SKCA-BR 15 50831588 50831588 insertion of <=200bp - GTTT intron_variant SKCA-BR 15 50831588 50831588 insertion of <=200bp - GTTT upstream_gene_variant SKCA-BR 15 50833079 50833079 single base substitution C T intron_variant SKCA-BR 15 50833079 50833079 single base substitution C T upstream_gene_variant SKCA-BR 15 50833253 50833253 single base substitution G A 3_prime_UTR_variant SKCA-BR 15 50833253 50833253 single base substitution G A intron_variant SKCA-BR 15 50833253 50833253 single base substitution G A missense_variant S218F 653C>T SKCA-BR 15 50833253 50833253 single base substitution G A upstream_gene_variant SKCA-BR 15 50839035 50839035 single base substitution C T upstream_gene_variant SKCA-BR 15 50843360 50843360 single base substitution G A upstream_gene_variant SKCA-BR 15 50843512 50843512 single base substitution G A upstream_gene_variant SKCM-US 15 50788176 50788176 single base substitution C T downstream_gene_variant SKCM-US 15 50791221 50791221 single base substitution C T downstream_gene_variant SKCM-US 15 50830987 50830987 single base substitution G A 3_prime_UTR_variant SKCM-US 15 50830987 50830987 single base substitution G A exon_variant SKCM-US 15 50830987 50830987 single base substitution G A missense_variant S241F 722C>T SKCM-US 15 50833252 50833252 single base substitution G A 3_prime_UTR_variant SKCM-US 15 50833252 50833252 single base substitution G A intron_variant SKCM-US 15 50833252 50833252 single base substitution G A synonymous_variant S218S 654C>T SKCM-US 15 50833252 50833252 single base substitution G A upstream_gene_variant SKCM-US 15 50833302 50833302 single base substitution C T 3_prime_UTR_variant SKCM-US 15 50833302 50833302 single base substitution C T intron_variant SKCM-US 15 50833302 50833302 single base substitution C T missense_variant E202K 604G>A SKCM-US 15 50833302 50833302 single base substitution C T upstream_gene_variant STAD-US 15 50791187 50791187 single base substitution G C downstream_gene_variant STAD-US 15 50836810 50836810 single base substitution G A intron_variant STAD-US 15 50836810 50836810 single base substitution G A synonymous_variant T74T 222C>T STAD-US 15 50836866 50836866 single base substitution T C intron_variant STAD-US 15 50836866 50836866 single base substitution T C missense_variant N56D 166A>G STAD-US 15 50838687 50838687 single base substitution G A exon_variant STAD-US 15 50838687 50838687 single base substitution G A synonymous_variant F12F 36C>T UCEC-US 15 50788072 50788072 single base substitution G T downstream_gene_variant UCEC-US 15 50788200 50788200 single base substitution A G downstream_gene_variant UCEC-US 15 50789404 50789404 single base substitution C T downstream_gene_variant UCEC-US 15 50790820 50790820 single base substitution A C downstream_gene_variant UCEC-US 15 50790857 50790857 single base substitution C A downstream_gene_variant UCEC-US 15 50830995 50830995 single base substitution A G 3_prime_UTR_variant UCEC-US 15 50830995 50830995 single base substitution A G exon_variant UCEC-US 15 50830995 50830995 single base substitution A G synonymous_variant I238I 714T>C UCEC-US 15 50833255 50833255 single base substitution G A 3_prime_UTR_variant UCEC-US 15 50833255 50833255 single base substitution G A intron_variant UCEC-US 15 50833255 50833255 single base substitution G A synonymous_variant C217C 651C>T UCEC-US 15 50833255 50833255 single base substitution G A upstream_gene_variant UCEC-US 15 50833339 50833339 single base substitution G T exon_variant UCEC-US 15 50833339 50833339 single base substitution G T intron_variant UCEC-US 15 50833339 50833339 single base substitution G T synonymous_variant I189I 567C>A UCEC-US 15 50833339 50833339 single base substitution G T upstream_gene_variant UCEC-US 15 50835837 50835837 single base substitution G T intron_variant UCEC-US 15 50835837 50835837 single base substitution G T missense_variant F134L 402C>A UCEC-US 15 50835837 50835837 single base substitution G T upstream_gene_variant UCEC-US 15 50835873 50835873 single base substitution T G intron_variant UCEC-US 15 50835873 50835873 single base substitution T G synonymous_variant A122A 366A>C UCEC-US 15 50835873 50835873 single base substitution T G upstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-F4-6570-01 COSM1373373 c.979C>A p.H327N Substitution - Missense 15:50500810-50500810 - T2269 COSM264621 c.724G>A p.E242K Substitution - Missense 15:50538803-50538803 - 3N09-VS-3T09 COSM4979189 c.532G>C p.E178Q Substitution - Missense 15:50541192-50541192 - 587376 COSM1232096 c.308A>G p.D103G Substitution - Missense 15:50543749-50543749 - I2L-P7-Tumor-Organoid COSM5363160 c.765T>C p.A255A Substitution - coding silent 15:50538762-50538762 - BCM265T COSM4955160 c.453A>G p.L151L Substitution - coding silent 15:50543604-50543604 - P110 COSM190273 c.706G>A p.A236T Substitution - Missense 15:50538821-50538821 - TCGA-JW-A5VL-01 COSM4846451 c.497C>G p.S166C Substitution - Missense 15:50541227-50541227 - S01297 COSM5667469 c.570C>G p.L190L Substitution - coding silent 15:50541154-50541154 - MO_1012 COSM5550698 c.280G>A p.A94T Substitution - Missense 15:50543777-50543777 - ESCC_76 COSM4846451 c.497C>G p.S166C Substitution - Missense 15:50541227-50541227 - SC_9096 COSM5559220 c.890T>C p.L297P Substitution - Missense 15:50529858-50529858 - TCGA-22-5482-01 COSM701084 c.487G>A p.E163K Substitution - Missense 15:50541237-50541237 - TCGA-HU-A4GX-01 COSM4055447 c.222C>T p.T74T Substitution - coding silent 15:50544613-50544613 - TCGA-AP-A056-01 COSM962576 c.729T>C p.I243I Substitution - coding silent 15:50538798-50538798 - SJHGG025_D COSM4970156 c.386C>T p.T129M Substitution - Missense 15:50543671-50543671 - TCGA-BQ-5882-01 COSM3987994 c.294C>T p.A98A Substitution - coding silent 15:50543763-50543763 - BN34T COSM3746383 c.138G>T p.L46F Substitution - Missense 15:50544697-50544697 - T3152 COSM4739920 c.458delA p.K153fs*45 Deletion - Frameshift 15:50543599-50543599 - TCGA-B0-5116-01 COSM470769 c.618C>T p.N206N Substitution - coding silent 15:50541106-50541106 - TCGA-22-1016-01 COSM701085 c.916C>T p.R306W Substitution - Missense 15:50529832-50529832 - TCGA-B0-5098-01 COSM1493420 c.659A>G p.Y220C Substitution - Missense 15:50541065-50541065 - CHEWS031 COSM4055447 c.222C>T p.T74T Substitution - coding silent 15:50544613-50544613 - TCGA-BS-A0UV-01 COSM962577 c.666C>T p.C222C Substitution - coding silent 15:50541058-50541058 - HCC068T COSM5824365 c.734G>T p.C245F Substitution - Missense 15:50538793-50538793 - TCGA-A8-A09Z-01 COSM190273 c.706G>A p.A236T Substitution - Missense 15:50538821-50538821 - 169 COSM3730004 c.696_697insT p.Q233fs*17 Insertion - Frameshift 15:50538830-50538831 - TCGA-AG-A002-01 COSM264622 c.387G>A p.T129T Substitution - coding silent 15:50543670-50543670 - TCGA-BG-A0MC-01 COSM962580 c.381A>C p.A127A Substitution - coding silent 15:50543676-50543676 - PCSI_0224_Pa_P_526 COSM3786524 c.926C>G p.P309R Substitution - Missense 15:50529822-50529822 - STC252 COSM5054335 c.667T>C p.S223P Substitution - Missense 15:50541057-50541057 - TCGA-FS-A1ZQ-06 COSM3501989 c.737C>T p.S246F Substitution - Missense 15:50538790-50538790 - 543 COSM5612536 c.223G>A p.G75R Substitution - Missense 15:50544612-50544612 - TCGA-BR-6566-01 COSM4055448 c.166A>G p.N56D Substitution - Missense 15:50544669-50544669 - LOVO COSM2216632 c.37G>A p.D13N Substitution - Missense 15:50546489-50546489 - 587376 COSM1232095 c.393G>T p.K131N Substitution - Missense 15:50543664-50543664 - T1764 COSM4739921 c.48C>T p.H16H Substitution - coding silent 15:50546478-50546478 - RK164_C01 COSM3700972 c.13C>A p.P5T Substitution - Missense 15:50546513-50546513 - ICGC_MB78 COSM3401808 c.15G>A p.P5P Substitution - coding silent 15:50546511-50546511 - TCGA-AG-A002-01 COSM264621 c.724G>A p.E242K Substitution - Missense 15:50538803-50538803 - CSCC-27-T COSM4534467 c.208G>A p.E70K Substitution - Missense 15:50544627-50544627 - T3064 COSM4739919 c.696delT p.Q233fs*5 Deletion - Frameshift 15:50538831-50538831 - 4133 COSM1645118 c.913T>G p.F305V Substitution - Missense 15:50529835-50529835 - A6 COSM5350265 c.21C>G p.L7L Substitution - coding silent 15:50546505-50546505 - BD114T COSM5504113 c.144C>G p.N48K Substitution - Missense 15:50544691-50544691 - TCGA-EJ-7793-01 COSM1470808 c.495A>G p.G165G Substitution - coding silent 15:50541229-50541229 - TCGA-FW-A3R5-06 COSM3887111 c.619G>A p.E207K Substitution - Missense 15:50541105-50541105 - CHC1053T COSM251283 c.953delA p.N318fs*>22 Deletion - Frameshift 15:50500836-50500836 - TCGA-AX-A05Z-01 COSM962579 c.417C>A p.F139L Substitution - Missense 15:50543640-50543640 - TCGA-EE-A29S-06 COSM3501990 c.669C>T p.S223S Substitution - coding silent 15:50541055-50541055 - BCM265T COSM4955160 c.453A>G p.L151L Substitution - coding silent 15:50543604-50543604 - TCGA-CJ-4899-01 COSM470770 c.456A>T p.K152N Substitution - Missense 15:50543601-50543601 - 107430 COSM95487 c.778A>G p.I260V Substitution - Missense 15:50538749-50538749 - TCGA-AX-A0J0-01 COSM962578 c.582C>A p.I194I Substitution - coding silent 15:50541142-50541142 - S02376 COSM5696941 c.695T>C p.F232S Substitution - Missense 15:50538832-50538832 - C608 COSM4442752 c.770G>T p.R257M Substitution - Missense 15:50538757-50538757 - LIM2551 COSM4643908 c.486T>C p.Y162Y Substitution - coding silent 15:50541238-50541238 - TCGA-BR-8680-01 COSM4055449 c.36C>T p.F12F Substitution - coding silent 15:50546490-50546490 - TCGA-06-0192-01 COSM3401808 c.15G>A p.P5P Substitution - coding silent 15:50546511-50546511 - CHC1053T COSM251283 c.953delA p.N318fs*>22 Deletion - Frameshift 15:50500836-50500836 - 86576 COSM95488 c.579C>G p.S193R Substitution - Missense 15:50541145-50541145 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.677675;Hs.677676;Hs.677677;Hs.677679;Hs.677680;Hs.677681;Hs.677682;Hs.677683;Hs.677684;Hs.677685;Hs.677686;Hs.677687;Hs.677688;Hs.677689;Hs.677690;Hs.677691;Hs.677692;Hs.677693;Hs.677694;Hs.677695;Hs.677696;Hs.677697;Hs.677698;Hs.677699;Hs.677700;Hs.677701;Hs.677702;Hs.677703;Hs.677704;Hs.677705;Hs.677706;Hs.677707;Hs.677708;Hs.677709;Hs.677711;Hs.677714;Hs.677715;Hs.677716;Hs.677717;Hs.677718;Hs.677719;Hs.677720;Hs.677721;Hs.677722;Hs.677725;Hs.677726;Hs.677727;Hs.677728;Hs.677729;Hs.677730;Hs.677731;Hs.677732;Hs.677733;Hs.677734;Hs.677735;Hs.677736;Hs.677737;Hs.677738;Hs.677739;Hs.677740;Hs.677742;Hs.677743;Hs.677744;Hs.677745;Hs.677747;Hs.677749;Hs.677750;Hs.677751;Hs.677752;Hs.677753;Hs.677754;Hs.677756;Hs.677758 15q21.1

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer C A Nonsense p.G102* c.304G>T 15 50835935 LUAD C G Missense p.R167T c.500G>C 15 50833406 CM C T Missense p.A57T c.169G>A 15 50836863 CM C T Missense p.E158K c.472G>A 15 50833434 LUSC C T Synonymous p.P5P c.15G>A 15 50838708 GBM C T Synonymous p.P5P c.15G>A 15 50838708 MB G A Missense p.R301W c.901C>T 15 50822029 LUSC G A Missense p.S241F c.722C>T 15 50830987 CM G A Missense p.T27I c.80C>T 15 50836952 CM G A Synonymous p.F264F c.792C>T 15 50830917 HNSC G A Synonymous p.N201N c.603C>T 15 50833303 RCCC G A Synonymous p.S218S c.654C>T 15 50833252 CM T A Missense p.K147N c.441A>T 15 50835798 RCCC T C Missense p.S64G c.190A>G 15 50836842 LUAD T C Synonymous p.G160G c.480A>G 15 50833426 PRAD T - Frameshift p.N313Tfs*46 c.938delA 15 50793033 HC T G Missense p.Q129H c.387A>C 15 50835852 COREAD T G Synonymous p.A122A c.366A>C 15 50835873 UCEC