PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ARIH2 RAB40A 26186194 biogrid exp PSME3 RAB40A 26186194 biogrid exp LYRM7 RAB40A 26186194 biogrid exp RAB40A CUL5 26186194 biogrid exp HSP90AA1 RAB40A 22939624 biogrid exp RAB40A FAM192A 26186194 biogrid exp RAB40A ANKRD27 25661869 biogrid exp COPS6 RAB40A 26186194 biogrid exp RAB40A ISCA1 26186194 biogrid exp HSP90AB1 RAB40A 22939624 intact exp TCEB1 RAB40A 26186194, 25402006 biogrid exp, pred RAB40AL RAB40A 26186194, 23023127 biogrid exp, pred RAB40A RAB24 23023127 pred PAK1 RAB40A 23023127 pred RAB40A SYNGAP1 23023127 pred GNB1 RAB40A 23023127 pred JUP RAB40A 23023127 pred RAB40A PLCE1 23023127 pred RAB15 RAB40A 23023127 pred RANBP1 RAB40A 23023127 pred ARF4 RAB40A 23023127 pred RASSF6 RAB40A 23023127 pred RAB40A RAB6B 23023127 pred RAB40A PLEKHG2 23023127 pred EXOC8 RAB40A 23023127 pred RAB40A RAB22A 23023127 pred DNM2 RAB40A 23023127 pred ARL4C RAB40A 23023127 pred RALGPS2 RAB40A 23023127, 16082366 pred RAB40A TNPO1 23023127 pred RAB40A AGAP1 23023127 pred ARL1 RAB40A 23023127 pred RGL2 RAB40A 16082366 pred ARAP3 RAB40A 23023127 pred DIRAS1 RAB40A 23023127 pred SNX32 RAB40A 23023127 pred ARL4A RAB40A 23023127 pred RAB40A DOK1 23023127 pred PKN1 RAB40A 23023127 pred REM2 RAB40A 23023127 pred IQGAP3 RAB40A 23023127 pred RAB42 RAB40A 23023127 pred RGL3 RAB40A 23023127 pred RAB40A RASAL2 23023127 pred RAB27B RAB40A 23023127 pred RASSF5 RAB40A 23023127 pred ARL3 RAB40A 23023127 pred RAB40A ARHGEF10L 23023127 pred RAPGEF1 RAB40A 23023127, 16082366 pred RAB3D RAB40A 23023127 pred RAB10 RAB40A 23023127 pred ARHGEF37 RAB40A 23023127 pred RND2 RAB40A 23023127 pred RRAS RAB40A 23023127 pred RHOG RAB40A 23023127 pred RAB40A RAB23 23023127 pred RAB40A DNAJC27 23023127 pred RAB2A RAB40A 23023127 pred RAB40A ARHGDIG 23023127 pred RAB40A RAB1B 23023127 pred PREX2 RAB40A 23023127 pred RAB40A RASD1 23023127 pred RAB40A RAB1C 23023127 pred RAB40A IFT27 23023127 pred RAB40A RGL1 23023127, 16082366 pred PLEKHG4 RAB40A 23023127 pred RAB40A RASL10B 23023127 pred RHEB RAB40A 23023127 pred RAB40A RASD2 23023127 pred RIN1 RAB40A 23023127, 16082366 pred RANBP2 RAB40A 23023127 pred RAB29 RAB40A 23023127 pred GEM RAB40A 23023127 pred RAP1B RAB40A 23023127 pred ARFGEF3 RAB40A 23023127 pred BCAR3 RAB40A 23023127, 16082366 pred RAP1GAP RAB40A 23023127 pred CDC42 RAB40A 23023127 pred RAB31 RAB40A 23023127 pred PAK4 RAB40A 23023127 pred ARHGAP1 RAB40A 23023127 pred WAS RAB40A 23023127 pred RAB40A ARL8B 23023127 pred RAB40A LOH12CR1 23023127 pred RASGRF2 RAB40A 23023127, 16082366 pred RHOA RAB40A 23023127 pred ARHGEF25 RAB40A 23023127 pred RAB39A RAB40A 23023127 pred RAB40A RAB17 23023127 pred RASGEF1A RAB40A 23023127 pred DIAPH1 RAB40A 23023127 pred RAB40A RAB6C 23023127 pred RAB25 RAB40A 23023127 pred RALBP1 RAB40A 23023127 pred RAB40A RAB26 23023127 pred PSD RAB40A 23023127 pred Ras-related protein Rap-1b-like protein RAB40A 23023127 pred REM1 RAB40A 23023127 pred RASGEF1B RAB40A 16082366 pred RAP1A RAB40A 23023127 pred RAB40A RIT1 23023127 pred FGD1 RAB40A 23023127 pred RAC3 RAB40A 23023127 pred RAB40A SYTL4 16082366 pred RAB40A GBF1 23023127 pred RAB40A OSBPL7 23023127 pred RALB RAB40A 23023127 pred KALRN RAB40A 23023127 pred RAB32 RAB40A 23023127 pred RHOT1 RAB40A 23023127 pred RAB40A TTN 23023127 pred RAB40A STARD8 23023127 pred RAB40A ARL5A 23023127 pred RAB40A ARHGEF1 23023127 pred ARHGEF39 RAB40A 23023127 pred MCF2 RAB40A 23023127 pred RAB40A RIT2 23023127 pred RAB11A RAB40A 23023127 pred NRAS RAB40A 23023127 pred ARHGDIA RAB40A 23023127 pred PAK2 RAB40A 23023127 pred ARFIP1 RAB40A 23023127 pred TBC1D22A RAB40A 23023127 pred IQGAP1 RAB40A 23023127 pred RAB7A RAB40A 23023127 pred ARHGEF11 RAB40A 23023127 pred RAB38 RAB40A 23023127 pred RAB11FIP2 RAB40A 23023127 pred TIAM2 RAB40A 23023127 pred RAB40A RAB37 23023127 pred RAB3B RAB40A 23023127 pred ARL17A, ARL17B RAB40A 23023127 pred RGL4 RAB40A 23023127, 16082366 pred HRAS RAB40A 23023127 pred SH2D3C RAB40A 16082366 pred RHOB RAB40A 23023127 pred MCF2L RAB40A 23023127 pred RAC1 RAB40A 23023127 pred PDPK1 RAB40A 23023127 pred SOS1 RAB40A 23023127, 16082366 pred ERAS RAB40A 23023127 pred VAV1 RAB40A 23023127 pred VSTM4 RAB40A 23023127 pred RALGDS RAB40A 23023127, 16082366 pred G3BP1 RAB40A 23023127 pred RASL11A RAB40A 23023127 pred RAB40A PLEKHF1 23023127 pred RAB4A RAB40A 23023127 pred RHOH RAB40A 23023127 pred RAB11B RAB40A 23023127 pred RAPGEF6 RAB40A 23023127 pred RAB36 RAB40A 23023127 pred RAB40A ARHGAP35 23023127 pred MAPK1 RAB40A 23023127 pred STX12 RAB40A 23023127 pred CSE1L RAB40A 23023127 pred RAP2A RAB40A 23023127 pred RAB40A AGAP2 23023127 pred ABR RAB40A 23023127 pred RAB40A SGSM3 23023127 pred RAP2B RAB40A 23023127 pred RAB4B RAB40A 23023127 pred ARHGAP4 RAB40A 23023127 pred KPNB1 RAB40A 23023127 pred SH2B2 RAB40A 23023127 pred FGD3 RAB40A 23023127 pred DAB2IP RAB40A 23023127 pred GARNL3 RAB40A 23023127 pred FAM109B RAB40A 23023127 pred MCF2L2 RAB40A 23023127 pred RASAL3 RAB40A 23023127 pred RAB43 RAB40A 23023127 pred GDI1 RAB40A 23023127 pred PRKCB RAB40A 23023127 pred RASA2 RAB40A 23023127 pred ARHGEF9 RAB40A 23023127 pred RAB40A 23023127 pred RAB9A RAB40A 23023127 pred PSD4 RAB40A 23023127 pred RAB27A RAB40A 23023127 pred RAB40A RASL10A 23023127 pred KPNA3 RAB40A 23023127 pred RASEF RAB40A 23023127 pred OBSCN RAB40A 23023127 pred RHOQ RAB40A 23023127 pred RAB28 RAB40A 23023127 pred TBC1D8 RAB40A 23023127 pred RABL3 RAB40A 23023127 pred RAB40A RAB9B 23023127 pred RAB40A RASL12 23023127 pred RAB40A PSD2 23023127 pred VAV2 RAB40A 23023127 pred RAB40A AGAP3 23023127 pred RAB40A RAB21 23023127 pred RAB40A RIN2 23023127, 16082366 pred RAB40A RAB33B 23023127 pred RAB40A RABGEF1 23023127 pred RAB40A RABGEF1 23023127 pred GNA12 RAB40A 23023127 pred RAB40A RAP2C 23023127 pred ARL10 RAB40A 23023127 pred IQSEC1 RAB40A 23023127 pred RHOC RAB40A 23023127 pred SOS2 RAB40A 23023127, 16082366 pred RAB40A NKIRAS1 23023127 pred RAB40A SNX6 23023127 pred RAB5A RAB40A 23023127 pred ICA1 RAB40A 23023127 pred TIAM1 RAB40A 23023127 pred RHOD RAB40A 23023127 pred RAB40A RPH3A 16082366 pred RASGRP3 RAB40A 23023127 pred RHEBL1 RAB40A 23023127 pred RAB40A ARL15 23023127 pred ARF1 RAB40A 23023127 pred RAB40B RAB40A 23023127 pred RAB40A CYTH4 23023127 pred PRKG2 RAB40A 23023127 pred RAB40A RHOF 23023127 pred RABIF RAB40A 23023127 pred RAB40A RERG 23023127 pred RAB3A RAB40A 23023127 pred RAB40A RAB39B 23023127 pred ARL14 RAB40A 23023127 pred TRIO RAB40A 23023127 pred RAB40A ALS2 23023127 pred RAB40A SAR1A 23023127 pred ROCK2 RAB40A 23023127 pred ARFRP1 RAB40A 23023127 pred ARF5 RAB40A 23023127 pred NF1 RAB40A 23023127 pred RAB40A RAB3C 23023127 pred ARF6 RAB40A 23023127 pred NUTF2 RAB40A 23023127 pred RAB40A EXOC2 23023127 pred RAB40A ITSN2 23023127 pred RAB40A RASSF1 23023127 pred RAB14 RAB40A 23023127 pred RAB40A ARL8A 23023127 pred RAB40A RAB18 23023127 pred RAB40A FARP1 23023127 pred RAB5B RAB40A 23023127 pred RAB13 RAB40A 23023127 pred NET1 RAB40A 23023127 pred RAB40A DOCK9 23023127 pred Fos39347_1 RAB40A 25402006 pred RHOT2 RAB40A 23023127 pred RAPGEF3 RAB40A 23023127, 16082366 pred RAB5C RAB40A 23023127 pred ARHGEF18 RAB40A 23023127 pred RAB11FIP3 RAB40A 23023127 pred RASGEF1C RAB40A 16082366 pred RAC2 RAB40A 23023127 pred ROCK1 RAB40A 23023127 pred RAB40A DIRAS2 23023127 pred PIK3CG RAB40A 23023127 pred RAB2B RAB40A 23023127 pred RASA1 RAB40A 23023127 pred GNA11 RAB40A 23023127 pred RAB40A VAV3 23023127 pred RAB40A FGD4 23023127 pred RAN RAB40A 23023127 pred RAB6A RAB40A 23023127 pred RAB40A ARL6 23023127 pred RAB40A PSD3 23023127 pred RAB40A SAR1B 23023127 pred RAB40A GULP1 23023127 pred RAB40A RERGL 23023127 pred RAB40A RHOJ 23023127 pred RAB40A RAB20 23023127 pred RASGRP2 RAB40A 16082366 pred RAB12 RAB40A 23023127 pred XPO1 RAB40A 23023127 pred RHOU RAB40A 23023127 pred RAB40A ARHGEF12 23023127 pred RAB40A ARL11 23023127 pred RAB40A PICK1 23023127 pred ARF3 RAB40A 23023127 pred ARHGAP33 RAB40A 23023127 pred RASGRP1 RAB40A 16082366 pred MRAS RAB40A 23023127 pred RAB40A RHOV 23023127 pred RRAD RAB40A 23023127 pred RAB40A RAB40A 23023127 pred RAB30 RAB40A 23023127 pred RCC1 RAB40A 23023127 pred DOK2 RAB40A 23023127 pred RAB40A RAPGEF5 23023127 pred RAB35 RAB40A 23023127 pred RAB40A ARL5B 23023127 pred RAB40A RAPGEF4 23023127 pred RAB40A NKIRAS2 23023127 pred ARFIP2 RAB40A 23023127 pred RALA RAB40A 23023127 pred GAPVD1 RAB40A 23023127 pred RAB1A RAB40A 23023127 pred DIRAS3 RAB40A 23023127 pred GNAS RAB40A 23023127 pred RGS14 RAB40A 23023127 pred KRAS RAB40A 23023127 pred ITSN1 RAB40A 23023127 pred RAB40A CYTH2 23023127 pred FGD6 RAB40A 23023127 pred RAB41 RAB40A 23023127 pred RRAS2 RAB40A 23023127 pred RAB40A RABL2B 23023127 pred RAB40A ARFGEF2 23023127 pred RALGPS1 RAB40A 23023127 pred ARHGAP5 RAB40A 23023127 pred RND3 RAB40A 23023127 pred ARHGAP6 RAB40A 23023127 pred RAF1 RAB40A 23023127 pred TRIM23 RAB40A 23023127 pred RAB33A RAB40A 23023127 pred RAB40A RND1 23023127 pred RAB40A RABL2A 23023127 pred ARL4D RAB40A 23023127 pred GNA13 RAB40A 23023127 pred RAB40A RASL11B 23023127 pred ARL2 RAB40A 23023127 pred RAB40A RAPGEFL1 23023127, 16082366 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8WXH6 Q8CHW5 affinity chromatography technology 20360680 physical association X 2 Q8WXH6 P07900-2 affinity chromatography technology 22939624 physical association X 2 P0CG48 Q8WXH6 affinity chromatography technology 21890473 physical association X 2 Q8WXH6 Q8CHW5 pull down 20360680 physical association X 2 Q8WXH6 A0A024RD80 luminescence based mammalian interactome mapping 22939624 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality ARIH2 RAB40A 26186194 0004 HT RAB40AL RAB40A 26186194 0004 HT TCEB1 RAB40A 26186194 0004 HT LYRM7 RAB40A 26186194 0004 HT COPS6 RAB40A 26186194 0004 HT RAB40A CUL5 26186194 0004 HT RAB40A ISCA1 26186194 0004 HT RAB40A FAM192A 26186194 0004 HT RAB40A HEL-S-283 26186194 0004 HT ARIH2 RAB40A 26186194 0004 HT RAB40AL RAB40A 26186194 0004 HT TCEB1 RAB40A 26186194 0004 HT LYRM7 RAB40A 26186194 0004 HT COPS6 RAB40A 26186194 0004 HT RAB40A CUL5 26186194 0004 HT RAB40A ISCA1 26186194 0004 HT RAB40A FAM192A 26186194 0004 HT RAB40A HEL-S-283 26186194 0004 HT HSP90AB1 RAB40A 22939624 0729 HT RAB40A ANKRD27 25661869 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8WXH6 P07900 RAB40A HSP90AA1 0.126 22939624 Q8WXH6 Q7L0Q8 RAB40A RHOU 0.183 26598620 Q8WXH6 Q8CHW5 RAB40A CCDC64B 0.236 20360680 Q8WXH6 Q7L5N1 RAB40A COPS6 0.126 26186194 Q8WXH6 Q5U5X0 RAB40A LYRM7 0.126 26186194 Q8WXH6 Q15369 RAB40A TCEB1 0.126 26186194 Q8WXH6 P61289 RAB40A PSME3 0.126 26186194 Q8WXH6 P0C0E4 RAB40A RAB40AL 0.126 26186194 Q8WXH6 O95376 RAB40A ARIH2 0.126 26186194 Q8WXH6 P08238 RAB40A HSP90AB1 0.126 22939624 Q93034 Q8WXH6 CUL5 RAB40A 0.126 26186194 Q9BUE6 Q8WXH6 ISCA1 RAB40A 0.126 26186194 Q9GZU8 Q8WXH6 FAM192A RAB40A 0.126 26186194 Q96NW4 Q8WXH6 ANKRD27 RAB40A 0.309 25661869

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 CCDC64B RAB40A MI:0362 inference MI:0461 interaction database ARIH2 RAB40A MI:0045 experimental interaction detection MI:0461 interaction database HSP90AA1 RAB40A MI:0045 experimental interaction detection MI:0461 interaction database HSP90AB1 RAB40A MI:0045 experimental interaction detection MI:0461 interaction database RAB40AL RAB40A MI:0045 experimental interaction detection MI:0461 interaction database UBC RAB40A MI:0045 experimental interaction detection MI:0461 interaction database PSME3 RAB40A MI:0045 experimental interaction detection MI:0461 interaction database TCEB1 RAB40A MI:0045 experimental interaction detection MI:0461 interaction database LYRM7 RAB40A MI:0045 experimental interaction detection MI:0461 interaction database RHOU RAB40A MI:0045 experimental interaction detection MI:0461 interaction database COPS6 RAB40A MI:0045 experimental interaction detection MI:0461 interaction database RAB40A CUL5 MI:0045 experimental interaction detection MI:0461 interaction database RAB40A ANKRD27 MI:0045 experimental interaction detection MI:0461 interaction database RAB40A ISCA1 MI:0045 experimental interaction detection MI:0461 interaction database RAB40A FAM192A MI:0045 experimental interaction detection MI:0461 interaction database