PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBC SH3RF3 20696164 mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ADAM15 SH3RF3 16374509 hprd,biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G YWHAB SH3RF3 24255178 biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CDC42 SH3RF3 20696164, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAC1 SH3RF3 20696164, 25402006 biogrid,mint,intact exp, pred GP GP G G GP G G G GP G G G GP G G GP G G GP G GP GP G GP GP G GP GP G PAK2 SH3RF3 16374509, 25402006 hprd,biogrid,mint,intact exp, pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP G G GP G GP GP GP GP GP G G SH3RF3 SH3KBP1 23023127 pred G G G G GP GP G G G G G G G GP G G GP G G G GP G G G G GP G G G SH3RF3 STAM 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G GRAP2 SH3RF3 23023127 pred P P P P P P P P P P P P P P P SUMO3 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 BAIAP2 23023127 pred P P G G GP GP G GP P G GP GP GP GP P GP GP GP G GP GP P P P P GP GP G PSIP1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 SAMSN1 23023127 pred G GP G GP P G P GP P P GP GP GP GP P P P P GP GP GP P SRGAP3 SH3RF3 23023127 pred GP G G G G GP G GP GP G GP G G G G G GP G G G G G G GP G G G RASA1 SH3RF3 23023127 pred GP G G G GP GP G G G G G G G G G G GP G G G GP G G G G G GP G G SKAP1 SH3RF3 23023127 pred G G G G GP G G G G G G G GP GP G G G G G G G G G G G GP G G G UBXN2A SH3RF3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSTPIP1 SH3RF3 23023127 pred G G GP G GP G GP GP G G G G GP G G SH3RF3 NSFL1C 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TMUB2 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 ABI2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SH3RF3 HERPUD2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 TDRD1 23023127 pred P P P P P P P P P P P P P P P P P P P P P GP SH3RF3 SH3GL2 23023127 pred G GP G G G GP GP G G SH3RF3 MYO15B 23023127 pred RIMBP3C SH3RF3 23023127 pred P P P P SH3RF3 RIN2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP GP GP P G SH3RF3 EPS8L2 23023127 pred GP GP G GP P GP G GP GP GP G G GP GP G GP G GP GP GP P GP P GP GP G BAG6 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 SH3YL1 23023127 pred GP G G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G MLK4 SH3RF3 23023127 pred P GP G G GP GP G GP G GP GP GP GP G GP GP GP G GP G GP GP P GP GP G SH3RF3 MYO15A 23023127 pred GP G G G G GP G G GP G GP G G G G GP GP GP GP G GP G G GP GP GP GP G BTK SH3RF3 23023127 pred G G GP G G GP GP G G GP G SASH3 SH3RF3 23023127 pred GP G G G G GP G G GP G G G GP GP G G GP G GP G GP GP GP G G GP GP GP G SH3RF3 SNX18 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP G G GP GP GP G GP G GP GP G RGS14 SH3RF3 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G RIMBP2 SH3RF3 23023127 pred P P G P GP G P P G GP P P G GP GP GP G P P P GP P P GP P G SH3RF3 SH3GL1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G CTTN SH3RF3 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MIA SH3RF3 23023127 pred P P P GP G GP P P P P G G GP G GP P G G GP P SH3RF3 PACSIN3 23023127 pred GP GP GP G GP P P GP P G G GP GP GP GP GP GP GP GP GP GP P G FCHSD2 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP P GP GP GP GP G G FYB SH3RF3 23023127 pred G G G GP G G G G G G G GP G G G G G G G G GP G SORBS2 SH3RF3 25402006, 23023127 pred GP GP G P GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP P G SRGAP1 SH3RF3 23023127 pred G GP G GP G G GP G GP GP G G G GP GP G GP G G G GP G G GP G SH3RF3 UHRF2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 RIMBP3 23023127 pred NCF1 SH3RF3 23023127 pred P P P P CIDEA SH3RF3 23023127 pred G G G G G G G G NGEF SH3RF3 23023127 pred P GP G P GP G P GP G GP GP P GP G GP GP G GP P GP P P GP P GP GP G SH3RF3 OTOR 23023127 pred P G G P G P P P P P P P P GP P P P GP P P P G PLCG1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBXN7 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ARHGEF7 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G SASH1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G G GP G GP G GP GP GP GP G G GP GP G UBXN2B SH3RF3 23023127 pred G GP G G G G G G GP G GP G GP G G GP G GP G G G GP G G GP G GP GP G UBASH3A SH3RF3 23023127 pred P P G P P P G PHF1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 UBQLN1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3D21 SH3RF3 23023127 pred P GP G G GP P G GP GP G GP GP P GP GP GP P GP G GP P GP GP GP P P GP G SH3RF3 UBTD2 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G SPTAN1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 PACSIN1 23023127 pred G GP G G P G P GP G SH3RF3 OSTF1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G NCK1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G SH3RF2 SH3RF3 23023127 pred P P P GP P P P P P P P P P P P GP PARK2 SH3RF3 23023127 pred P GP G P GP G GP GP G GP P P G P GP GP P G P GP GP GP P GP G NCF1C SH3RF3 23023127 pred BCAR1 SH3RF3 23023127 pred GP GP G P GP G GP GP G GP GP GP GP GP GP GP GP G GP GP GP GP GP GP GP GP G CRKL SH3RF3 23023127 pred GP G G G GP GP G G GP G G G GP GP G GP GP G GP G GP GP G G GP GP GP G G PIK3R1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ARHGEF37 SH3RF3 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G P G GP G GP G GP G GP GP G PIK3CA SH3RF3 23023127 pred GP GP G P GP G GP GP G GP GP GP GP G P GP GP GP G P GP GP GP GP GP GP GP AMPH SH3RF3 23023127 pred G G G G GP G G GP G G G G G GP G GP G G G G G G G G G RBBP6 SH3RF3 23023127 pred GP G G G G GP G GP GP G GP GP GP G G GP GP G G G GP G GP G GP GP GP GP G SH3RF3 ASAP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G MAP3K11 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 MIA2 23023127 pred P P P P GP GP P P G GP P P GP P P P G SH3RF3 UBASH3B 23023127 pred P P G G GP GP G P P G P P GP P P GP P GP P P P P GP P P SH3RF3 ABI3 23023127 pred G G G G GP GP G GP GP G GP G GP GP G GP GP G G G G G GP GP GP G G SUMO2 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G GRB2 SH3RF3 25402006, 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 PPP1R13L 23023127 pred GP G G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G USP14 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 TDRD3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP SH3RF1 SH3RF3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SH3RF3 SH3GLB1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ARHGEF9 SH3RF3 23023127 pred GP GP G P GP G GP GP G GP GP G G G G GP G GP G GP G GP P G GP G P G UBXN11 SH3RF3 23023127 pred G GP G G G GP G GP P G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G LIMS2 SH3RF3 23023127 pred G G G G G GP G GP GP G GP GP G G G G GP G G G G G G G G G G G G ARHGEF16 SH3RF3 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G RAPH1 SH3RF3 23023127 pred GP GP G P GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G AHI1 SH3RF3 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G G GP GP GP GP G NEDD9 SH3RF3 23023127 pred GP GP G G GP GP G GP GP GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NOSTRIN SH3RF3 23023127 pred GP GP G P GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G NCK2 SH3RF3 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBFD1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STAC2 SH3RF3 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP P GP G GP GP GP GP G TRIP10 SH3RF3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NCF1B SH3RF3 23023127 pred LYN SH3RF3 23023127 pred GP G G G GP GP G G GP G G G GP GP G GP GP G GP G GP GP GP GP GP GP G G ARID4B SH3RF3 23023127 pred GP GP G G G GP G G GP G GP G G GP G G GP G GP G GP GP G G G G GP GP G SH3RF3 VAV3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G SH3RF3 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 STAC3 23023127 pred G G G G G G G G G G G G G G LCK SH3RF3 23023127 pred G G GP G G G G G G GP G G G G G GP G SH3PXD2A SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G SORBS3 SH3RF3 25402006, 23023127 pred G G G G G GP G GP GP G GP GP G G G GP GP G GP G GP GP GP GP GP G GP G G ARHGEF6 SH3RF3 25402006, 23023127 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G G G G G GP G GP G G ARAF SH3RF3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SH3RF3 CASS4 23023127 pred P P P P P P P P P P P P P P P GP P P P SH3RF3 BAIAP2L1 23023127 pred P GP P P G P GP GP GP GP P G GP P P GP G GP GP GP P GP P GP GP FYN SH3RF3 23023127 pred G GP G G GP GP G G GP G GP GP G GP G G GP G G G G G G G G GP G G G UBXN8 SH3RF3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G EPS8L1 SH3RF3 23023127 pred GP GP G G G G GP GP GP G G GP G G GP G GP G G GP GP GP G G NOXA1 SH3RF3 23023127 pred GP GP G G G GP G G GP G GP GP G G G GP GP GP GP G GP GP GP G GP G GP GP G SMN1, SMN2 SH3RF3 23023127 pred P P P P P P P P P P P P P P P P P P P P MYO1E SH3RF3 23023127 pred GP P G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G G GP G GP GP G HERPUD1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 ARHGAP26 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G SH3RF3 DBNL 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G NPHP1 SH3RF3 23023127 pred P P G P P GP P P P P P G GP G P P P G P P GP SYN1 SH3RF3 25402006 pred G G G G GP G G GP G G G G GP G G G G P G G ITK SH3RF3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G MIDN SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G SH3RF3 PPP1R13B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 FAF1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MATK SH3RF3 23023127 pred P P G G GP GP P P P GP GP GP GP GP P P P P P P P GP P P VAV1 SH3RF3 23023127 pred GP GP G GP GP G P P G P GP GP GP G GP GP G GP G GP G GP P P GP GP GP G SH3RF3 UBTD1 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G G GP GP GP G P G GP G G G GP G NCF4 SH3RF3 23023127 pred G G G GP G GP GP G G G G GP G NCF4 SH3RF3 23023127 pred G G G GP G GP GP G G G G GP G SH3RF3 PEX13 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAF1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 TMUB1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G SH3RF3 SGSM3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G MAPK8IP2 SH3RF3 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G MAP3K9 SH3RF3 23023127 pred P GP G P GP G GP G GP GP P G G GP GP P GP G GP GP GP GP GP GP GP GP G NEB SH3RF3 23023127 pred G P G G G G P G G G G G GP G P G SH3PXD2B SH3RF3 23023127 pred GP GP G G G GP G G GP G GP G GP G G G GP GP GP G GP GP GP G G G GP GP G SH3RF3 SORBS1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G ABI1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EFS SH3RF3 23023127 pred GP G G G G GP G G GP G GP P GP G G G GP GP GP G GP GP GP G G G G G G STAM2 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PLCG2 SH3RF3 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G SH3RF3 SH3GLB2 23023127 pred G GP G G G GP G G GP G GP G GP G G GP G GP G GP G G G G GP GP GP G MYO1F SH3RF3 23023127 pred G G G G GP G G G G G G G GP G G G G G G G G GP G GP G G G ABL1 SH3RF3 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G BZRAP1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G SH3RF3 ASPSCR1 23023127 pred GP GP G P GP G GP P G GP GP GP GP G GP GP P GP G GP GP GP GP GP G GP GP CRK SH3RF3 23023127 pred GP G G G G G G GP GP G GP GP G G G GP G G GP G GP GP GP GP GP G GP G G PIK3R2 SH3RF3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NEBL SH3RF3 23023127 pred GP GP G G G G G GP GP G GP GP GP GP G GP G G GP G G G G G GP P GP G G SH3RF3 ITSN2 23023127 pred G G G G G GP G G GP G GP GP G G G GP GP G GP G GP GP G G GP G GP GP G PHF20L1 SH3RF3 23023127 pred G GP G G G GP G GP GP G GP G G G G GP GP G GP G GP G G GP GP G GP GP G MAP3K10 SH3RF3 23023127 pred P P P P P P P P P P P P P P P P P P P P P KALRN SH3RF3 23023127 pred P P G P GP G P P G P P P P P GP P P P P P P GP P P SH3RF3 RUSC1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G HCLS1 SH3RF3 23023127 pred G G G G GP GP G G G G G G GP GP G G GP G G G G G G G G GP G G G CSK SH3RF3 23023127 pred G G G G GP GP G G GP G G G GP GP G GP GP G GP G GP G G G GP GP GP GP G ABL2 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NOXO1 SH3RF3 23023127 pred G G G SF3A1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ARHGAP4 SH3RF3 23023127 pred G G G GP G GP GP G G G GP G RAD23B SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DNMBP SH3RF3 23023127 pred GP GP G G G GP G GP GP G G G GP G G G GP GP G G GP GP G GP G G GP G G ITSN1 SH3RF3 23023127 pred G GP G G G GP G GP GP G GP GP GP GP G GP GP G G G GP G GP GP GP G GP GP G OBSCN SH3RF3 23023127 pred GP P P P GP GP GP P P GP G P P P P G P GP GP GP GP GP GP P UBQLNL SH3RF3 23023127 pred P P P P P P P P G P P P P GP BIN1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SUMO4 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G G GP GP GP G GP GP GP GP G GP GP GP G SH3RF3 UBL7 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G RUSC2 SH3RF3 23023127 pred GP GP G P GP G GP GP G GP GP GP GP G P GP GP P G P P GP GP GP GP GP GP G BAIAP2L2 SH3RF3 23023127 pred P P G P P GP GP P P P GP P P P P P P P GP P GP P NCF2 SH3RF3 23023127 pred G G GP G G G GP GP G G G G G G G G GP G G PKN2 SH3RF3 21836163 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP GP GP GP GP GP GP GP G SH3RF3 CD2AP 23023127 pred GP GP G GP P G G GP GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP SH3RF3 SH3GL3 23023127 pred G G G G GP G G G G G G G G G GP G GP G G G G G G GP GP G YES1 SH3RF3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TRIO SH3RF3 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G FCHSD1 SH3RF3 23023127 pred P P P P P P P P P GP P P P P G P P P P P GP P P ARHGEF19 SH3RF3 23023127 pred G G G G G G G G G G G SH3RF3 MAPK8IP1 23023127 pred P P G P GP G P P G P P P P P GP P G P P P P P P P GP EPS8L3 SH3RF3 23023127 pred G G G G GP GP G GP GP G P G GP G G GP GP GP GP G G G GP GP G GP G VAV2 SH3RF3 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP G RIMBP3B SH3RF3 23023127 pred LASP1 SH3RF3 23023127 pred G G G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP G GP G GP GP GP G G VIM SH3RF3 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G G GP GP GP G G G G G G GP G GP G SH3RF3 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBC SH3RF3 23023127 pred SRGAP2 SH3RF3 23023127 pred G G G G G G G G G G G G G G G G G G SH3RF3 SH3BP4 23023127 pred GP GP G P GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8TEJ3 Q13444 pull down 16374509 direct interaction X 2 Q8TEJ3 pull down 16374509 direct interaction X 2 P0CG48 Q8TEJ3 affinity chromatography technology 20696164 physical association X 2 Q8TEJ3 A4D2P0 affinity chromatography technology 20696164 physical association X 2 Q8TEJ3 A0A024RAE4 affinity chromatography technology 20696164 physical association X 2 Q8TEJ3 A4D2P0 pull down 20696164 direct interaction X 2 Q8TEJ3 A4D2P0 affinity chromatography technology 20696164 physical association X 2 Q8TEJ3 P31946 affinity chromatography technology 24255178 physical association X 2 Q13177 Q8TEJ3 pull down 16374509 direct interaction X 2 Q8TEJ3 Q13444-10 in vitro 16374509 - X 2 Q8TEJ3 Q13444-10 in vitro 16374509 - X 2 Q13177 Q8TEJ3 in vitro 16374509 - X 2 Q13177 Q8TEJ3 in vitro 16374509 - X 2 Q8TEJ3 anti tag coimmunoprecipitation 24255178 association C 142 Q8TEJ3 Q13444 filter binding 16374509 physical association X 2 A4D2P1 Q8TEJ3 anti tag coimmunoprecipitation 20696164 physical association X 2 A4D2P1 Q8TEJ3 anti tag coimmunoprecipitation 20696164 physical association X 2 A4D2P1 Q8TEJ3 solid phase assay 20696164 direct interaction X 2 A4D2P1 Q8TEJ3 anti tag coimmunoprecipitation 20696164 physical association X 2 A4D2P1 Q8TEJ3 anti tag coimmunoprecipitation 20696164 physical association X 2 A4D2P1 Q8TEJ3 anti tag coimmunoprecipitation 20696164 physical association X 2 P0CG48 Q8TEJ3 anti tag coimmunoprecipitation 20696164 physical association X 2 Q90VU7 Q8TEJ3 filter binding 16374509 physical association X 2 Q13177 Q8TEJ3 phage display 16374509 physical association X 2 Q13177 Q8TEJ3 filter binding 16374509 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality YWHAB SH3RF3 24255178 0007 HT SH3RF3 HEL-S-1 24255178 0004 HT YWHAB SH3RF3 24255178 0007 HT SH3RF3 HEL-S-1 24255178 0004 HT RAC1 SH3RF3 20696164,20696164,20696164,20696164 0007,0892,0004,0096 LC PAK2 SH3RF3 16374509,16374509,16374509 0096,0084,0049 LC ADAM15 SH3RF3 16374509,16374509 0096,0049 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9HCD6 Q8TEJ3 TANC2 SH3RF3 0.126 unassigned1312 Q8TEJ3 O15075 SH3RF3 DCLK1 0.126 unassigned1312 Q8TEJ3 O43166 SH3RF3 SIPA1L1 0.126 unassigned1312 Q8TEJ3 O60307 SH3RF3 MAST3 0.126 unassigned1312 Q8TEJ3 O60573 SH3RF3 EIF4E2 0.126 unassigned1312 Q8TEJ3 O75044 SH3RF3 SRGAP2 0.126 unassigned1312 Q8TEJ3 O75420 SH3RF3 GIGYF1 0.126 unassigned1312 Q8TEJ3 P0CG48 SH3RF3 UBC 0.21 20696164 Q8TEJ3 P21359 SH3RF3 NF1 0.126 unassigned1312 Q8TEJ3 P30307 SH3RF3 CDC25C 0.126 unassigned1312 Q8TEJ3 P56524 SH3RF3 HDAC4 0.126 unassigned1312 Q8TEJ3 P60953 SH3RF3 CDC42 0.21 20696164 Q8TEJ3 Q12923 SH3RF3 PTPN13 0.126 unassigned1312 Q8TEJ3 Q5TCZ1 SH3RF3 SH3PXD2A 0.126 unassigned1312 Q8TEJ3 Q5VZ89 SH3RF3 DENND4C 0.126 unassigned1312 Q8TEJ3 Q6Y7W6 SH3RF3 GIGYF2 0.126 unassigned1312 Q8TEJ3 Q86X27 SH3RF3 RALGPS2 0.126 unassigned1312 Q8TEJ3 Q8IVT5 SH3RF3 KSR1 0.126 unassigned1312 Q8TEJ3 Q8TEH3 SH3RF3 DENND1A 0.126 unassigned1312 Q90VU7 Q8TEJ3 NEF SH3RF3 0.126 16374509 Q96QZ7 Q8TEJ3 MAGI1 SH3RF3 0.126 unassigned1312 Q96S53 Q8TEJ3 TESK2 SH3RF3 0.126 unassigned1312 Q9BPZ7 Q8TEJ3 MAPKAP1 SH3RF3 0.126 unassigned1312 Q9BQK8 Q8TEJ3 LPIN3 SH3RF3 0.126 unassigned1312 Q9BST9 Q8TEJ3 RTKN SH3RF3 0.126 unassigned1312 Q9NQT8 Q8TEJ3 KIF13B SH3RF3 0.126 unassigned1312 Q9NRR6 Q8TEJ3 INPP5E SH3RF3 0.126 unassigned1312 Q9P244 Q8TEJ3 LRFN1 SH3RF3 0.126 unassigned1312 Q9P2M7 Q8TEJ3 CGN SH3RF3 0.126 unassigned1312 Q9UHB6 Q8TEJ3 LIMA1 SH3RF3 0.126 unassigned1312 Q9ULJ3 Q8TEJ3 ZBTB21 SH3RF3 0.126 unassigned1312 Q9ULR3 Q8TEJ3 PPM1H SH3RF3 0.126 unassigned1312 Q9Y3M2 Q8TEJ3 CBY1 SH3RF3 0.126 unassigned1312 Q9Y597 Q8TEJ3 KCTD3 SH3RF3 0.126 unassigned1312 Q8TEJ3 P04601 SH3RF3 NEF 0.183 16374509 Q8TEJ3 P31946 SH3RF3 YWHAB 0.236 24255178 Q8TEJ3 P63000 SH3RF3 RAC1 0.765 20696164 Q8TEJ3 Q13444 SH3RF3 ADAM15 0.286 16374509 Q8TEJ3 Q13177 SH3RF3 PAK2 0.376 16374509

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SIAH2 SH3RF3 MI:0362 inference MI:0461 interaction database UBC SH3RF3 MI:0045 experimental interaction detection MI:0461 interaction database YWHAB SH3RF3 MI:0045 experimental interaction detection MI:0461 interaction database CDC42 SH3RF3 MI:0045 experimental interaction detection MI:0461 interaction database RAC1 SH3RF3 MI:0045 experimental interaction detection MI:0461 interaction database OGDH SH3RF3 MI:0362 inference MI:0461 interaction database IFT88 SH3RF3 MI:0362 inference MI:0461 interaction database PAK2 SH3RF3 MI:0045 experimental interaction detection MI:0461 interaction database ADAM15 SH3RF3 MI:0045 experimental interaction detection MI:0461 interaction database SH3RF1 SH3RF3 MI:0362 inference MI:0461 interaction database SH3RF3 LATS2 MI:0362 inference MI:0461 interaction database SH3RF3 GAR1 MI:0362 inference MI:0461 interaction database SH3RF3 OGDHL MI:0362 inference MI:0461 interaction database