Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 12 112645401 rs2074356 G A rs2074356 2.00E-09 URIC ACID CREATININE Renal function-related traits (BUN) HPOID:0000077 DOID:557 C intron GWASdb_drug 12 112645401 rs2074356 G A rs2074356 6.73E-11 CITALOPRAM ANTIDEPRESSIVE AGENTS, SECOND-GENERATION Major depressive disorder HPOID:0000716 DOID:1470 C intron GWASdb_drug 12 112652523 rs10850016 T C rs10850016 1.99E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_drug 12 112677279 rs11066209 A G rs11066209 1.20E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_drug 12 112703732 rs2301757 A C rs2301757 1.20E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 T cds-synon GWASdb_drug 12 112707398 rs11066226 T C rs11066226 1.20E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_drug 12 112817783 rs11066280 T A rs11066280 1.44E-08 CITALOPRAM ANTIDEPRESSIVE AGENTS, SECOND-GENERATION Major depressive disorder HPOID:0000716 DOID:1470 T intron GWASdb_drug 12 112598321 rs3519 G A rs3519 7.00E-04 Multiple complex diseases HPOID:0000118 NA G UTR-3 GWASdb_trait 12 112598321 rs3519 G A rs3519 9.36E-06 Type 1 diabetes HPOID:0100651 DOID:9744 G UTR-3 GWASdb_trait 12 112605611 rs2242496 T C rs2242496 2.60E-05 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 A intron GWASdb_trait 12 112610714 rs11066188 G A rs11066188 6.24E-10 Other erythrocyte phenotypes HPOID:0001877 DOID:74 G intron GWASdb_trait 12 112610714 rs11066188 G A rs11066188 3.19E-06 Primary biliary cirrhosis HPOID:0002613 DOID:12236 G intron GWASdb_trait 12 112610714 rs11066188 G A rs11066188 4.30E-12 Soluble ICAM-1 HPOID:0001658 DOID:9452|DOID:5844 G intron GWASdb_trait 12 112610714 rs11066188 G A rs11066188 4.10E-10 Hypothyroidism HPOID:0000821 DOID:1459 G intron GWASdb_trait 12 112610714 rs11066188 G A rs11066188 9.35E-10 Red blood cell traits HPOID:0001877 DOID:74 G intron GWASdb_trait 12 112610714 rs11066188 G A rs11066188 2.86E-09 Tetralogy of Fallot HPOID:0001636 DOID:6419 G intron GWASdb_trait 12 112610714 rs11066188 G A rs11066188 2.12E-04 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 12 112621886 rs3741993 C T rs3741993 3.61E-04 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 G intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 8.00E-12 Biomedical quantitative traits HPOID:0000118 NA C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 3.90E-21 Esophageal cancer (squamous cell) HPOID:0011459 DOID:5041 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 9.00E-59 Alcohol consumption HPOID:0000707 DOID:1574|DOID:0050741 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 2.00E-31 Esophageal cancer HPOID:0011459 DOID:5041 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 3.00E-126 Gamma glutamyl transpeptidase HPOID:0001626|HPOID:0002664|HPOID:0005978 DOID:409|DOID:1574 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 7.00E-37 HDL cholesterol HPOID:0003107 DOID:14502|DOID:1461|DOID:3393 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 1.49E-13 Coronary heart disease HPOID:0001677 DOID:3393 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 2.00E-09 Renal function-related traits (BUN) HPOID:0000077 DOID:557 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 7.66E-40 Drinking behavior HPOID:0000707 DOID:0050741|DOID:1574 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 6.73E-11 Coronary heart disease HPOID:0001677 DOID:3393 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 6.73E-11 Major depressive disorder HPOID:0000716 DOID:1470 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 1.19E-75 Alcohol (ever vs. never) HPOID:0000707 DOID:1574|DOID:0050741 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 6.42E-08 Alcohol consumption HPOID:0000707 DOID:1574|DOID:0050741 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 1.00E-16 Glycemic traits HPOID:0005978 DOID:9352 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 6.00E-09 Glycemic traits HPOID:0005978 DOID:9352 C intron GWASdb_trait 12 112645401 rs2074356 G A rs2074356 6.00E-14 Glycemic traits HPOID:0005978 DOID:9352 C intron GWASdb_trait 12 112647744 rs11066193 A C rs11066193 2.60E-05 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 A intron GWASdb_trait 12 112652523 rs10850016 T C rs10850016 1.99E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_trait 12 112652523 rs10850016 T C rs10850016 2.60E-05 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 C intron GWASdb_trait 12 112667675 rs1005902 T G rs1005902 1.62E-06 Multiple complex diseases HPOID:0000118 NA G cds-synon GWASdb_trait 12 112677279 rs11066209 A G rs11066209 1.20E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_trait 12 112679176 rs4767530 C T rs4767530 2.60E-05 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 C intron GWASdb_trait 12 112703732 rs2301757 A C rs2301757 1.20E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 T cds-synon GWASdb_trait 12 112703732 rs2301757 A C rs2301757 2.60E-05 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 T cds-synon GWASdb_trait 12 112707398 rs11066226 T C rs11066226 1.20E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_trait 12 112708426 rs2285809 T C rs2285809 2.19E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 12 112708426 rs2285809 T C rs2285809 6.80E-07 Type 1 diabetes HPOID:0100651 DOID:9744 A intron GWASdb_trait 12 112710206 rs12228104 T G rs12228104 3.40E-05 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 G intron GWASdb_trait 12 112735492 rs11066245 A G rs11066245 2.20E-05 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 A intron GWASdb_trait 12 112736118 rs77768175 A G rs77768175 3.16E-09 Coronary heart disease HPOID:0001677 DOID:3393 A intron GWASdb_trait 12 112740315 rs1859246 G A rs1859246 3.62E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 12 112740709 rs4357753 T C rs4357753 3.61E-04 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 T intron GWASdb_trait 12 112741811 rs11066247 G A rs11066247 2.60E-05 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 G intron GWASdb_trait 12 112747662 rs12229891 G A rs12229891 2.60E-05 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 G intron GWASdb_trait 12 112754449 rs7965261 G A rs7965261 3.53E-04 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 G intron GWASdb_trait 12 112777433 rs1468251 T C rs1468251 7.96E-04 Multiple complex diseases HPOID:0000118 NA G intron GWASdb_trait 12 112777433 rs1468251 T C rs1468251 3.84E-06 Type 1 diabetes HPOID:0100651 DOID:9744 G intron GWASdb_trait 12 112781844 rs4766898 C T rs4766898 3.80E-05 Response to alcohol consumption (flushing response) HPOID:0000707 DOID:1574|DOID:0050741 C intron GWASdb_trait 12 112812282 rs1362036 C T rs1362036 3.18E-04 Blood pressure HPOID:0011025 DOID:10763 C intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 2.50E-21 Esophageal cancer (squamous cell) HPOID:0011459 DOID:5041 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 1.00E-35 Blood pressure HPOID:0011025 DOID:10763 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 8.00E-31 Blood pressure HPOID:0011025 DOID:10763 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 2.00E-15 Esophageal cancer HPOID:0011459 DOID:5041 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 3.00E-63 Metabolite levels HPOID:0001939 DOID:655 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 8.00E-22 Metabolite levels HPOID:0001939 DOID:655 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 6.84E-17 Coronary heart disease HPOID:0001677 DOID:3393 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 2.00E-11 Coronary heart disease HPOID:0001677 DOID:3393 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 3.00E-215 Drinking behavior HPOID:0000707 DOID:0050741|DOID:1574 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 1.44E-08 Coronary heart disease HPOID:0001677 DOID:3393 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 1.44E-08 Major depressive disorder HPOID:0000716 DOID:1470 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 2.76E-09 Alcohol consumption HPOID:0000707 DOID:1574|DOID:0050741 T intron GWASdb_trait 12 112817783 rs11066280 T A rs11066280 2.94E-76 Alcohol (ever vs. never) HPOID:0000707 DOID:1574|DOID:0050741 T intron GWASdb_trait 12 112817847 rs7311681 T G rs7311681 8.60E-06 Urinary metabolites HPOID:0000079 DOID:557 G intron GWASdb_trait