PTM - CPLM Gene Name UniProt ID Type Position Code PRPF8; PRPC8 Q6P2Q9 Acetylation 1463 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 278 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 727 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 93 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 267 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 428 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 449 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 452 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 460 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 480 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 525 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 609 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 702 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 705 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 746 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 785 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 833 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 932 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1020 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1131 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1158 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1210 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1344 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1392 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1434 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1443 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1449 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1463 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1732 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1735 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1792 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1801 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1859 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1901 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1958 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 301 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 442 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1505 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2140 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2293 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 218 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2034 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2112 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 983 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 555 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2031 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 43 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 721 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1994 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1290 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2108 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1898 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 837 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1306 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1831 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1300 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1425 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2113 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1866 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 68 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 511 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 36 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 941 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1838 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1012 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 847 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 853 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1144 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 987 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 528 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 533 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2249 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2098 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1222 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2049 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 2070 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1840 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1132 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 29 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 366 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1993 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 670 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 674 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1649 K PRPF8; PRPC8 Q6P2Q9 Ubiquitination 1294 K

PTM - dbPAF Gene Name UniProt ID Position Type Species PRPF8; PRPC8 Q6P2Q9 1027 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1028 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1091 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1113 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1128 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1204 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1318 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1338 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1355 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1358 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1369 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1404 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1432 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1470 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1512 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1524 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1539 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1608 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1851 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1887 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 1991 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2037 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2042 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2056 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2057 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2058 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2059 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2060 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2062 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2064 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2079 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2087 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2091 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2093 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2102 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2129 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2132 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2205 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 2294 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 231 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 236 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 237 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 239 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 247 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 254 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 26 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 394 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 501 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 645 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 679 S Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 7 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 733 T Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 742 Y Homo sapiens(Human) PRPF8; PRPC8 Q6P2Q9 859 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q6P2Q9 K43-ac Acetylation KWQQLQAkRYAEKRK Q6P2Q9 K609-ac Acetylation IRMCKDLkHLIYYRF Q6P2Q9 K1463-ac Acetylation THQRHDGkLWNLNNy Q6P2Q9 R8-m1 Methylation MAGVFPYrGPGNPVP Q6P2Q9 R79-m1 Methylation DHGDMTNrKFRHDKR Q6P2Q9 K1020-m1 Methylation NNVVINYkDMNHTNS Q6P2Q9 R1151-m2 Methylation kHDVNLGrAVFWDIk Q6P2Q9 R1201-m1 Methylation CRILPKCrTSyEEFT Q6P2Q9 R1401-m1 Methylation QEAIAQNrRLtLEDL Q6P2Q9 R1414-m1 Methylation DLEDSWDrGIPrINT Q6P2Q9 R1418-m1 Methylation SWDrGIPrINTLFQk Q6P2Q9 K1425-m2 Methylation rINTLFQkDRHTLAy Q6P2Q9 K1425-m3 Methylation rINTLFQkDRHTLAy Q6P2Q9 K1425-m1 Methylation rINTLFQkDRHTLAy Q6P2Q9 K1443-m1 Methylation WRVRTDFkQYQVLkQ Q6P2Q9 K1516-m3 Methylation FEEsMKWkkLTNAQR Q6P2Q9 K1517-m3 Methylation EEsMKWkkLTNAQRs Q6P2Q9 R2086-m1 Methylation sAANLHLrtNHIyVs Q6P2Q9 S26-p Phosphorylation APLPDYMsEEkLQEk Q6P2Q9 Y94-p Phosphorylation VYLGALkyMPHAVLK Q6P2Q9 Y239-p Phosphorylation LPMMSTLyRLANQLL Q6P2Q9 Y254-p Phosphorylation TDLVDDNyFYLFDLK Q6P2Q9 Y394-p Phosphorylation FLKDTPLyTDNTANG Q6P2Q9 Y501-p Phosphorylation LQVCRQGyNMLNLLI Q6P2Q9 T645-p Phosphorylation LFFMRGItPLLERWL Q6P2Q9 S679-p Phosphorylation VTkQRVEsHFDLELR Q6P2Q9 T733-p Phosphorylation WkVPGLPtPIENMIL Q6P2Q9 Y742-p Phosphorylation IENMILRyVKAkADW Q6P2Q9 S859-p Phosphorylation VkSRLNQsQREELGL Q6P2Q9 Y871-p Phosphorylation LGLIEQAyDNPHEAL Q6P2Q9 Y1008-p Phosphorylation VDHNIADyMtAkNNV Q6P2Q9 T1010-p Phosphorylation HNIADyMtAkNNVVI Q6P2Q9 Y1091-p Phosphorylation PIRLFCRyIDRIHIF Q6P2Q9 Y1113-p Phosphorylation ARDLIQRyLTEHPDP Q6P2Q9 Y1128-p Phosphorylation NNENIVGyNNkKCWP Q6P2Q9 Y1204-p Phosphorylation LPKCrTSyEEFTHkD Q6P2Q9 S1338-p Phosphorylation GHVLIPQsDLRWSkQ Q6P2Q9 S1355-p Phosphorylation VGITHFRsGMsHEED Q6P2Q9 S1358-p Phosphorylation THFRsGMsHEEDQLI Q6P2Q9 Y1369-p Phosphorylation DQLIPNLyRYIQPWE Q6P2Q9 T1404-p Phosphorylation IAQNrRLtLEDLEDS Q6P2Q9 Y1432-p Phosphorylation kDRHTLAyDkGWRVR Q6P2Q9 Y1470-p Phosphorylation kLWNLNNyRTDMIQA Q6P2Q9 S1512-p Phosphorylation KASGFEEsMKWkkLT Q6P2Q9 S1524-p Phosphorylation kLTNAQRsGLNQIPN Q6P2Q9 S1539-p Phosphorylation RRFTLWWsPTINRAN Q6P2Q9 T1608-p Phosphorylation LDALEIEtVQKETIH Q6P2Q9 Y1671-p Phosphorylation IQLRWGDyDSHDIER Q6P2Q9 Y1741-p Phosphorylation MkANPALyVLRERIR Q6P2Q9 S1851-p Phosphorylation EVAALIRsLPVEEQP Q6P2Q9 S1887-p Phosphorylation PNIVIKGsELQLPFQ Q6P2Q9 T1972-p Phosphorylation HHIWPTLtDEEWIKV Q6P2Q9 Y1991-p Phosphorylation KDLILADyGkkNNVN Q6P2Q9 S2037-p Phosphorylation EkQTkEQsQLTAtQT Q6P2Q9 T2042-p Phosphorylation EQsQLTAtQTRTVNk Q6P2Q9 S2057-p Phosphorylation HGDEIITsTTSNyEt Q6P2Q9 Y2062-p Phosphorylation ITsTTSNyEtQTFSS Q6P2Q9 T2064-p Phosphorylation sTTSNyEtQTFSSKT Q6P2Q9 S2079-p Phosphorylation EWRVRAIsAANLHLr Q6P2Q9 T2087-p Phosphorylation AANLHLrtNHIyVsS Q6P2Q9 Y2091-p Phosphorylation HLrtNHIyVsSDDIK Q6P2Q9 S2093-p Phosphorylation rtNHIyVsSDDIKET Q6P2Q9 Y2102-p Phosphorylation DDIKETGyTYILPKN Q6P2Q9 S2189-p Phosphorylation PNESPQLsPQDVTTH Q6P2Q9 S2205-p Phosphorylation KIMADNPsWDGEKTI Q6P2Q9 Y2294-p Phosphorylation RHDPNMkyELQLANP Q6P2Q9 K29-ub Ubiquitination PDYMsEEkLQEkARK Q6P2Q9 K33-ub Ubiquitination sEEkLQEkARKWQQL Q6P2Q9 K93-ub Ubiquitination RVYLGALkyMPHAVL Q6P2Q9 K218-ub Ubiquitination QPLRDSRkYVNGSTY Q6P2Q9 K267-ub Ubiquitination LKAFFTSkALNMAIP Q6P2Q9 K278-ub Ubiquitination MAIPGGPkFEPLVRD Q6P2Q9 K301-ub Ubiquitination NEFNDINkIIIRQPI Q6P2Q9 K366-ub Ubiquitination ISHRHSVkSQEPLPD Q6P2Q9 K428-ub Ubiquitination ALDIPLVkNWYREHC Q6P2Q9 K449-ub Ubiquitination KVRVSYQkLLkYYVL Q6P2Q9 K452-ub Ubiquitination VSYQkLLkYYVLNAL Q6P2Q9 K460-ub Ubiquitination YYVLNALkHRPPKAQ Q6P2Q9 K480-ub Ubiquitination FRSFKATkFFQSTKL Q6P2Q9 K525-ub Ubiquitination LDYNFNLkPVkTLTT Q6P2Q9 K528-ub Ubiquitination NFNLkPVkTLTTKER Q6P2Q9 K555-ub Ubiquitination REVLRLTkLVVDSHV Q6P2Q9 K609-ub Ubiquitination IRMCKDLkHLIYYRF Q6P2Q9 K670-ub Ubiquitination RHSKGVAkTVTkQRV Q6P2Q9 K674-ub Ubiquitination GVAkTVTkQRVEsHF Q6P2Q9 K702-ub Ubiquitination DMMPEGIkQNkARTI Q6P2Q9 K705-ub Ubiquitination PEGIkQNkARTILQH Q6P2Q9 K727-ub Ubiquitination WKANIPWkVPGLPtP Q6P2Q9 K746-ub Ubiquitination ILRyVKAkADWWTNT Q6P2Q9 K769-ub Ubiquitination RRGATVDkTVCKKNL Q6P2Q9 K785-ub Ubiquitination RLTRLYLkAEQERQH Q6P2Q9 K853-ub Ubiquitination LKEAYSVkSRLNQsQ Q6P2Q9 K932-ub Ubiquitination YLWYEADkRRLFPPW Q6P2Q9 K941-ub Ubiquitination RLFPPWIkPADTEPP Q6P2Q9 K983-ub Ubiquitination MLESRFEkMYEkIDL Q6P2Q9 K987-ub Ubiquitination RFEkMYEkIDLTLLN Q6P2Q9 K1012-ub Ubiquitination IADyMtAkNNVVINY Q6P2Q9 K1020-ub Ubiquitination NNVVINYkDMNHTNS Q6P2Q9 K1131-ub Ubiquitination NIVGyNNkKCWPRDA Q6P2Q9 K1144-ub Ubiquitination DARMRLMkHDVNLGr Q6P2Q9 K1158-ub Ubiquitination rAVFWDIkNRLPRSV Q6P2Q9 K1210-ub Ubiquitination SyEEFTHkDGVWNLQ Q6P2Q9 K1222-ub Ubiquitination NLQNEVTkERTAQCF Q6P2Q9 K1300-ub Ubiquitination NKIQTRIkIGLNSkM Q6P2Q9 K1306-ub Ubiquitination IkIGLNSkMPSRFPP Q6P2Q9 K1344-ub Ubiquitination QsDLRWSkQTDVGIT Q6P2Q9 K1392-ub Ubiquitination VWAEYALkRQEAIAQ Q6P2Q9 K1434-ub Ubiquitination RHTLAyDkGWRVRTD Q6P2Q9 K1443-ub Ubiquitination WRVRTDFkQYQVLkQ Q6P2Q9 K1449-ub Ubiquitination FkQYQVLkQNPFWWT Q6P2Q9 K1463-ub Ubiquitination THQRHDGkLWNLNNy Q6P2Q9 K1649-ub Ubiquitination PSLLADSkDVMDSTT Q6P2Q9 K1732-ub Ubiquitination LIQQAMAkIMkANPA Q6P2Q9 K1735-ub Ubiquitination QAMAkIMkANPALyV Q6P2Q9 K1792-ub Ubiquitination VYRVTIHkTFEGNLT Q6P2Q9 K1801-ub Ubiquitination FEGNLTTkPINGAIF Q6P2Q9 K1831-ub Ubiquitination TSVWAGQkRLGQLAK Q6P2Q9 K1840-ub Ubiquitination LGQLAKWkTAEEVAA Q6P2Q9 K1859-ub Ubiquitination LPVEEQPkQIIVTRk Q6P2Q9 K1866-ub Ubiquitination kQIIVTRkGMLDPLE Q6P2Q9 K1901-ub Ubiquitination QACLKVEkFGDLILK Q6P2Q9 K1993-ub Ubiquitination LILADyGkkNNVNVA Q6P2Q9 K1994-ub Ubiquitination ILADyGkkNNVNVAS Q6P2Q9 K2031-ub Ubiquitination QQIAEIEkQTkEQsQ Q6P2Q9 K2034-ub Ubiquitination AEIEkQTkEQsQLTA Q6P2Q9 K2049-ub Ubiquitination tQTRTVNkHGDEIIT Q6P2Q9 K2140-ub Ubiquitination PPDNPQVkEIRCIVM Q6P2Q9 K2293-ub Ubiquitination VRHDPNMkyELQLAN

PTM - dbPTM UniProt ID Position Code Type Resources References Q6P2Q9 2 A Acetylation Swiss-Prot 1010711 19413330 Q6P2Q9 1463 K Acetylation Swiss-Prot 1010711 19608861 Q6P2Q9 1539 S Phosphorylation Swiss-Prot 1010711 18220336 Q6P2Q9 2042 T Phosphorylation Swiss-Prot 1010711 17525332 Q6P2Q9 2064 T Phosphorylation Swiss-Prot 1010711 17525332 Q6P2Q9 2079 S Phosphorylation Swiss-Prot 1010711 18669648 Q6P2Q9 1539 S Phosphorylation PhosphoELM.10011 18220336 Q6P2Q9 2079 S Phosphorylation PhosphoELM.10011 18669648 Q6P2Q9 2042 T Phosphorylation PhosphoELM.10011 17525332 Q6P2Q9 2064 T Phosphorylation PhosphoELM.10011 17525332 Q6P2Q9 1012 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 1020 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 1131 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 1144 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 1158 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 1210 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 1222 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 1306 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 1344 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 1392 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 1434 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 1443 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 1449 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 1463 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 1649 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 1732 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 1735 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 1792 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 1801 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 1859 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 1866 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 1901 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 1993 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 1994 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 2031 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 2034 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 2049 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 2140 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 218 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 2293 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 267 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 278 K Ubiquitylation Phosphositeplus.1010730 20639865;21890473;21906983 Q6P2Q9 29 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 301 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 366 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 428 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 449 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 452 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 460 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 480 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 555 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 609 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 670 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 674 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 702 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 705 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 727 K Ubiquitylation Phosphositeplus.1010730 20639865;21890473 Q6P2Q9 746 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 785 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 93 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6P2Q9 932 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q6P2Q9 941 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 983 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 987 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6P2Q9 1463 K Acetylation Phosphositeplus.1010730 19608861 Q6P2Q9 1539 S Phosphorylation Phosphositeplus.1010730 18220336;20068231 Q6P2Q9 2079 S Phosphorylation Phosphositeplus.1010730 18669648;19276368 Q6P2Q9 2205 S Phosphorylation Phosphositeplus.1010730 21406692 Q6P2Q9 859 S Phosphorylation Phosphositeplus.1010730 20068231 Q6P2Q9 2042 T Phosphorylation Phosphositeplus.1010730 17525332 Q6P2Q9 2064 T Phosphorylation Phosphositeplus.1010730 17525332 Q6P2Q9 2087 T Phosphorylation Phosphositeplus.1010730 19664994 Q6P2Q9 1470 Y Phosphorylation Phosphositeplus.1010730 20068231 Q6P2Q9 1991 Y Phosphorylation Phosphositeplus.1010730 20068231 Q6P2Q9 2091 Y Phosphorylation Phosphositeplus.1010730 18083107 Q6P2Q9 2102 Y Phosphorylation Phosphositeplus.1010730 17360941 Q6P2Q9 239 Y Phosphorylation Phosphositeplus.1010730 20068231 Q6P2Q9 1463 K Acetylation HPRD 9.0 19608861 Q6P2Q9 236 S Phosphorylation HPRD 9.0 20068231 Q6P2Q9 859 S Phosphorylation HPRD 9.0 20068231 Q6P2Q9 1027 S Phosphorylation HPRD 9.0 20068231 Q6P2Q9 1355 S Phosphorylation HPRD 9.0 19651622 Q6P2Q9 1539 S Phosphorylation HPRD 9.0 20068231 Q6P2Q9 2079 S Phosphorylation HPRD 9.0 18669648 Q6P2Q9 237 T Phosphorylation HPRD 9.0 20068231 Q6P2Q9 247 T Phosphorylation HPRD 9.0 20068231 Q6P2Q9 2042 T Phosphorylation HPRD 9.0 17525332 Q6P2Q9 2064 T Phosphorylation HPRD 9.0 17525332 Q6P2Q9 2087 T Phosphorylation HPRD 9.0 19664994 Q6P2Q9 239 Y Phosphorylation HPRD 9.0 20068231 Q6P2Q9 254 Y Phosphorylation HPRD 9.0 18452278,20068231 Q6P2Q9 1028 Y Phosphorylation HPRD 9.0 20068231 Q6P2Q9 1369 Y Phosphorylation HPRD 9.0 19651622 Q6P2Q9 1470 Y Phosphorylation HPRD 9.0 20068231 Q6P2Q9 1991 Y Phosphorylation HPRD 9.0 20068231 Q6P2Q9 2079 S Phosphorylation SysPTM 1.1 18669648

PTM - HPRD Symbol Position Code Type References PRPF8 1027 S Phosphorylation 20068231 PRPF8 1028 Y Phosphorylation 20068231 PRPF8 1355 S Phosphorylation 19651622 PRPF8 1369 Y Phosphorylation 19651622 PRPF8 1463 K Acetylation 19608861 PRPF8 1470 Y Phosphorylation 20068231 PRPF8 1539 S Phosphorylation 20068231 PRPF8 1991 Y Phosphorylation 20068231 PRPF8 2042 T Phosphorylation 17525332 PRPF8 2064 T Phosphorylation 17525332 PRPF8 2079 S Phosphorylation 18669648 PRPF8 2087 T Phosphorylation 19664994 PRPF8 236 S Phosphorylation 20068231 PRPF8 237 T Phosphorylation 20068231 PRPF8 239 Y Phosphorylation 20068231 PRPF8 247 T Phosphorylation 20068231 PRPF8 254 Y Phosphorylation 18452278,20068231 PRPF8 859 S Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q6P2Q9 1539 S 18220336 HTP Phosphorylation Q6P2Q9 2064 T 17525332 HTP Phosphorylation Q6P2Q9 2079 S 18669648 HTP Phosphorylation Q6P2Q9 2042 T 17525332 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q6P2Q9 2 N-acetylalanine 19413330;22223895 Q6P2Q9 859 Phosphoserine 20068231 Q6P2Q9 1358 Phosphoserine 23186163 Q6P2Q9 1425 N6,N6-dimethyllysine 24129315 Q6P2Q9 1463 N6-acetyllysine 19608861

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type PRPF8 IPI00007928 K 1463 HQRHDGaKLWNLNN acetylation PRPF8 IPI00007928 S 1539 RFTLWWpSPTINRA phosphorylation PRPF8 IPI00007928 S 2132 GYLYGVpSPPDNPQ phosphorylation PRPF8 IPI00007928 S 236 FTLPMMpSTLYRLA phosphorylation PRPF8 IPI00007928 S 679 TKQRVEpSHFDLEL phosphorylation PRPF8 IPI00007928 S 859 KSRLNQpSQREELG phosphorylation PRPF8 IPI00007928 T 231 YQRWQFpTLPMMST phosphorylation PRPF8 IPI00007928 T 237 TLPMMSpTLYRLAN phosphorylation PRPF8 IPI00007928 T 247 LANQLLpTDLVDDN phosphorylation PRPF8 IPI00007928 Y 1028 MNHTNSpYGIIRGL phosphorylation PRPF8 IPI00007928 Y 1470 LWNLNNpYRTDMIQ phosphorylation PRPF8 IPI00007928 Y 1991 DLILADpYGKKNNV phosphorylation PRPF8 IPI00007928 Y 2129 QIAGYLpYGVSPPD phosphorylation PRPF8 IPI00007928 Y 2294 HDPNMKpYELQLAN phosphorylation PRPF8 IPI00007928 Y 239 PMMSTLpYRLANQL phosphorylation PRPF8 IPI00007928 Y 254 DLVDDNpYFYLFDL phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 10594 115842 - K Ubiquitination 18425143 10594 115842 - K Ubiquitination 16196087 10594 115842 - K Ubiquitination 22178446 10594 115842 - K Ubiquitination 20639865 10594 115842 - K Ubiquitination 22118674 10594 115842 - K Ubiquitination 18781797 10594 115842 - K Ubiquitination 21987572 10594 115842 - K Ubiquitination 21963094 10594 115842 - K Ubiquitination 21139048 10594 115842 - K Ubiquitination 21890473 10594 115842 - K Ubiquitination 21906983 10594 115842 - K Sumoylation 19471022 10594 115842 - K Sumoylation 21252943 10594 115842 - K Ubiquitination 22505724 10594 115842 - K Ubiquitination 23000965 10594 115842 - K FAT10ylation 23862649 10594 115842 - K Neddylation 24654937 10594 115842 - K Ubiquitination 24816145 10594 115842 - K Sumoylation 25027693 10594 115842 - K Ubiquitination 25147182 10594 115842 - K Sumoylation 19596686 10594 115842 - K Neddylation 18247557

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID PRPF8 Homo sapiens (Human) 746; 1020; 1131; 278; 1443; 1958; 428; 1801; 1449; 1210; 267; 1344; 1792; 727 "746,LRYVKAKADWWTN; 1020,NVVINYKDMNHTN; 1131,IVGYNNKKCWPRD; 278,AIPGGPKFEPLVR; 1443,RVRTDFKQYQVLK; 1958,VILKPDKTTITEP; 428,LDIPLVKNWYREH; 1801,EGNLTTKPINGAI; 1449,KQYQVLKQNPFWW; 1210,YEEFTHKDGVWNL; 267,KAFFTSKALNMAI; 1344,SDLRWSKQTDVGI; 1792,YRVTIHKTFEGNL; 727,KANIPWKVPGLPT" 746:21890473; 1020:21890473; 1131:21890473; 278:21890473; 1443:21890473; 1958:21890473; 428:21890473; 1801:21890473; 1449:21890473; 1210:21890473; 267:21890473; 1344:21890473; 1792:21890473; 727:21890473 PRPF8 Homo sapiens (Human) 746; 1020; 1131; 278; 1443; 1958; 428; 1801; 1449; 1210; 267; 1344; 1792; 727 "746,LRYVKAKADWWTN; 1020,NVVINYKDMNHTN; 1131,IVGYNNKKCWPRD; 278,AIPGGPKFEPLVR; 1443,RVRTDFKQYQVLK; 1958,VILKPDKTTITEP; 428,LDIPLVKNWYREH; 1801,EGNLTTKPINGAI; 1449,KQYQVLKQNPFWW; 1210,YEEFTHKDGVWNL; 267,KAFFTSKALNMAI; 1344,SDLRWSKQTDVGI; 1792,YRVTIHKTFEGNL; 727,KANIPWKVPGLPT" 746:21890473; 1020:21890473; 1131:21890473; 278:21890473; 1443:21890473; 1958:21890473; 428:21890473; 1801:21890473; 1449:21890473; 1210:21890473; 267:21890473; 1344:21890473; 1792:21890473; 727:21890473 PRPF8 Homo sapiens (Human) 746; 1306; 2034; 609; 1222; 1020; 278; 1158; 1434; 2140; 1012; 674; 555; 702; 941; 2049; 1958; 218; 267; 932; 1649; 29; 449; 2031; 1344; 987; 1131; 785; 1463; 2293; 983; 1392; 1866; 670; 1443; 428; 1144; 1801; 1210; 1449; 1859; 1994; 366; 1993; 301; 1792; 727 "746,LRYVKAKADWWTN; 1306,KIGLNSKMPSRFP; 2034,EIEKQTKEQSQLT; 609,RMCKDLKHLIYYR; 1222,LQNEVTKERTAQC; 1020,NVVINYKDMNHTN; 278,AIPGGPKFEPLVR; 1158,AVFWDIKNRLPRS; 1434,HTLAYDKGWRVRT; 2140,PDNPQVKEIRCIV; 1012,ADYMTAKNNVVIN; 674,VAKTVTKQRVESH; 555,EVLRLTKLVVDSH; 702,MMPEGIKQNKART; 941,LFPPWIKPADTEP; 2049,QTRTVNKHGDEII; 1958,VILKPDKTTITEP; 218,PLRDSRKYVNGST; 267,KAFFTSKALNMAI; 932,LWYEADKRRLFPP; 1649,SLLADSKDVMDST; 29,DYMSEEKLQEKAR; 449,VRVSYQKLLKYYV; 2031,QIAEIEKQTKEQS; 1344,SDLRWSKQTDVGI; 987,FEKMYEKIDLTLL; 1131,IVGYNNKKCWPRD; 785,LTRLYLKAEQERQ; 1463,HQRHDGKLWNLNN; 2293,RHDPNMKYELQLA; 983,LESRFEKMYEKID; 1392,WAEYALKRQEAIA; 1866,QIIVTRKGMLDPL; 670,HSKGVAKTVTKQR; 1443,RVRTDFKQYQVLK; 428,LDIPLVKNWYREH; 1144,ARMRLMKHDVNLG; 1801,EGNLTTKPINGAI; 1210,YEEFTHKDGVWNL; 1449,KQYQVLKQNPFWW; 1859,PVEEQPKQIIVTR; 1994,LADYGKKNNVNVA; 366,SHRHSVKSQEPLP; 1993,ILADYGKKNNVNV; 301,EFNDINKIIIRQP; 1792,YRVTIHKTFEGNL; 727,KANIPWKVPGLPT" "746:21890473; 1306:21906983; 2034:21906983; 609:21906983; 1222:21906983; 1020:21890473,21906983; 278:21890473,21906983; 1158:21906983; 1434:21906983; 2140:21906983; 1012:21906983; 674:21906983; 555:21906983; 702:21906983; 941:21906983; 2049:21906983; 1958:21890473; 218:21906983; 267:21890473,21906983; 932:21906983; 1649:21906983; 29:21906983; 449:21890473,21906983; 2031:21906983; 1344:21890473,21906983; 987:21906983; 1131:21890473,21906983; 785:21906983; 1463:21906983; 2293:21906983; 983:21906983; 1392:21906983; 1866:21906983; 670:21906983; 1443:21890473,21906983; 428:21890473,21906983; 1144:21906983; 1801:21890473; 1210:21890473,21906983; 1449:21890473; 1859:21906983; 1994:21906983; 366:21906983; 1993:21906983; 301:21906983; 1792:21890473; 727:21890473" PRPF8 Homo sapiens (Human) 746; 1020; 1131; 278; 1443; 1958; 428; 1801; 1449; 1210; 267; 1344; 1792; 727 "746,LRYVKAKADWWTN; 1020,NVVINYKDMNHTN; 1131,IVGYNNKKCWPRD; 278,AIPGGPKFEPLVR; 1443,RVRTDFKQYQVLK; 1958,VILKPDKTTITEP; 428,LDIPLVKNWYREH; 1801,EGNLTTKPINGAI; 1449,KQYQVLKQNPFWW; 1210,YEEFTHKDGVWNL; 267,KAFFTSKALNMAI; 1344,SDLRWSKQTDVGI; 1792,YRVTIHKTFEGNL; 727,KANIPWKVPGLPT" 746:21890473; 1020:21890473; 1131:21890473; 278:21890473; 1443:21890473; 1958:21890473; 428:21890473; 1801:21890473; 1449:21890473; 1210:21890473; 267:21890473; 1344:21890473; 1792:21890473; 727:21890473 PRPF8 Homo sapiens (Human) 746; 1020; 1131; 278; 1443; 1958; 428; 1801; 1449; 1210; 267; 1344; 1792; 727 "746,LRYVKAKADWWTN; 1020,NVVINYKDMNHTN; 1131,IVGYNNKKCWPRD; 278,AIPGGPKFEPLVR; 1443,RVRTDFKQYQVLK; 1958,VILKPDKTTITEP; 428,LDIPLVKNWYREH; 1801,EGNLTTKPINGAI; 1449,KQYQVLKQNPFWW; 1210,YEEFTHKDGVWNL; 267,KAFFTSKALNMAI; 1344,SDLRWSKQTDVGI; 1792,YRVTIHKTFEGNL; 727,KANIPWKVPGLPT" 746:21890473; 1020:21890473; 1131:21890473; 278:21890473; 1443:21890473; 1958:21890473; 428:21890473; 1801:21890473; 1449:21890473; 1210:21890473; 267:21890473; 1344:21890473; 1792:21890473; 727:21890473