PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ADRB2 KCTD13 24561123 biogrid exp GP G G G G G G G GP G P GP GP G G GP G G GP G GP GP G G GP G GP GP G KCTD13 SPRTN 22902628 biogrid exp P G G P GP G P G G GP KCTD13 HSPB8 26186194 biogrid exp GP GP G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G KCTD13 ARMC7 16189514 hprd,biogrid,mint,intact exp GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP G GP GP G GP GP G KCTD13 ZMYND19 25416956,16189514 hprd,biogrid,mint,intact exp GP GP G G G GP G P GP G GP GP GP G G GP GP GP P G GP GP GP GP GP G GP GP G LNX1 KCTD13 16189514 hprd,biogrid,mint,intact exp GP G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP GP GP KCTD13 VTA1 16189514 hprd,biogrid,mint,intact exp G GP G G G GP G G GP G GP GP G G G GP GP GP GP G GP G GP G GP G GP GP G KCTD13 USP25 19615732 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G KAT7 KCTD13 16189514 hprd,biogrid,mint,intact exp GP GP G G G GP G GP GP G GP G GP G G GP GP GP GP G GP G GP GP GP G GP GP G PPARG KCTD13 16239304 biogrid exp GP P P GP P GP G GP P G GP P P P GP P KCTD13 KCTD13 25416956 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G SRPX KCTD13 19615732 biogrid,intact exp G G G G G GP G G GP G GP GP GP G G G GP G GP G G G G G G G GP GP G PLEC KCTD13 19615732 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G NUDT18 KCTD13 16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G CRK KCTD13 25814554 biogrid,intact exp GP G G G G G G GP GP G GP GP G G G GP G G GP G GP GP GP GP GP G GP G G FLNC KCTD13 26186194 biogrid exp G GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP G GP GP GP G GP GP G HSPA1L KCTD13 26186194 biogrid exp GP P G G G G G G G G P G G G G GP G RHOA KCTD13 19782033 biogrid exp GP GP G G G GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP G LAMB4 KCTD13 19615732 biogrid,intact exp P P P P P P P P P P P GP P P P CUL3 KCTD13 25416956,19782033,21145461, 23023127 biogrid,intact exp, pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G POLD2 KCTD13 11593007, 25402006, 21836163 hprd,biogrid,i2d exp, pred GP GP G G G GP G G GP G GP G GP G G GP GP GP GP G GP G G G GP G GP GP G KCTD13 KCTD10 26186194,19615732, 25402006, 16082366 biogrid,intact exp, pred G GP G G G GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP G PCNA KCTD13 11593007, 25402006, 21836163 hprd,biogrid,i2d exp, pred GP GP G G G G G G GP G GP G G G G GP G G GP G GP GP GP G GP G GP GP G TNFAIP1 KCTD13 25416956,21516116,26186194,19615732, 25402006, 23023127, 21836163, 16082366 biogrid,intact exp, pred G G G G G G G G GP G GP G G G G GP G G GP G G G GP G GP G GP G G ATP6V1A KCTD13 ortho G GP G G G GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP G RFC5 KCTD13 25402006 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP G GP GP GP G GP GP G KCTD13 KCNB2 16082366 pred G G G G G G G G G G G G G G G G G G G G GRIA2 KCTD13 16082366 pred G GP G G GP G KCNA4 KCTD13 23023127, 16082366 pred GP G P G P P P P P P P P P P P P P P P KCTD13 SHC3 23023127 pred P GP G GP P GP G P P P G P GP P P P P GP P GP P P KCNK3 KCTD13 16082366 pred G G G G G G G G G G G G G G G G G G G P G G G G CNGA2 KCTD13 16082366 pred P P P P P P P P P P P P KCTD13 KCND2 16082366 pred P P G GP P G P P P GP GP P G P P P KCTD13 KCND1 23023127 pred P P P G P P P P P P P P RGS14 KCTD13 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G CHAF1A KCTD13 25402006 pred G GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G UNG KCTD13 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G KCNV2 KCTD13 16082366 pred P P P P P P P P P P P P GP KCNMA1 KCTD13 16082366 pred GP GP G G G GP G G GP G GP GP GP G G GP GP GP G G GP GP GP G GP G G GP G KCNA5 KCTD13 16082366 pred P P P GP P G P P P P P P P P P P P P P P CACNB3 KCTD13 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G KCTD13 KCNG2 16082366 pred P P P P P P P P P P P P P P P P P P KCTD13 KCNN3 16082366 pred P P G GP P GP G P P P P GP P P P P P G GP P RAD23A KCTD13 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G KCNC4 KCTD13 23023127, 16082366 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP P GP GP GP G GP GP G KCNG4 KCTD13 23023127, 16082366 pred G GP G G GP G G G G GP G G G P GP G KCTD13 POLH 25402006 pred GP G G G G GP G GP GP G GP P P G GP GP GP G GP P GP GP GP G GP GP KCTD13 KCNH6 16082366 pred P P G G GP G GP GP G GP P P G P GP G GP G P GP GP GP GP P P kcnj12x KCTD13 16082366 pred KCTD18 KCTD13 23023127, 16082366 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G KCTD13 MUTYH 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G KCTD13 KCNJ9 16082366 pred G G G G G G G G G SOCS7 KCTD13 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KCNJ2 KCTD13 16082366 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G KCTD8 KCTD13 23023127 pred P P P KCNJ11 KCTD13 16082366 pred P P P P P P GP G P P KCTD13 KCNK15 16082366 pred P P P P P P P P CACNB1 KCTD13 16082366 pred P G G G G GP G G P G GP G G G GP GP G GP G GP GP G GP GP P GP G KCTD13 KCNK13 16082366 pred P P P G GRIA4 KCTD13 16082366 pred G G G G G G G G G KCTD13 KCNN1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G KCTD13 BTBD10 23023127 pred GP GP G G G GP G GP GP G GP G GP G G G GP G GP G GP GP GP G G G G GP G KCNN4 KCTD13 16082366 pred GP G G G G P G G G G G G G G G G G GP G G G G G GRIA1 KCTD13 16082366 pred G GP G P G GP G P KCTD13 KCNK12 16082366 pred G G G G G G KCNJ10 KCTD13 16082366 pred P P G GP G P P G GP P P G P GP P P P P P P P P P G KCNJ3 KCTD13 16082366 pred G G G G GP G G P G GP G P GP GP G G G G GP GP GP G GRIK1 KCTD13 16082366 pred P GP G G G GP G P P G P P G P GP GP P P P P P P P P KCNA6 KCTD13 16082366 pred P P G GP G P P G P GP P GP GP GP GP P P GP P P GP P KCTD13 KCNJ15 16082366 pred GP P G G P P P GP P GP GP P P GP GP GP GP GP GP G GP P KCTD1 KCTD13 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KCTD13 KCNS1 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KCTD13 KCTD12 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KCNQ3 KCTD13 16082366 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G SHKBP1 KCTD13 16082366 pred GP GP G G P G P GP G GP P GP G G GP P GP GP G GP GP G GP G GP P G CCNO KCTD13 25402006 pred G G G G G P G G G G G GP G G GP G GP G G GP GP GP KCNA3 KCTD13 23023127, 16082366 pred G G P G G P G GP CACNB2 KCTD13 16082366 pred GP G GP GP GP G GP GP P G G GP GP GP G P G GP G G GP P G GRIK4 KCTD13 16082366 pred CDC25C KCTD13 25402006 pred P P G G P P GP P P GP P P P P P P GP P GP G KCTD13 DSCC1 25402006 pred GP GP G G G GP G GP GP G GP GP P G G GP GP P GP P P GP GP GP GP GP G POLD1 KCTD13 25402006 pred GP P G G P G GP GP GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G POLD3 KCTD13 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G KCNA1 KCTD13 23023127, 16082366 pred GP GP G G G GP G GP GP G P GP P G GP GP GP GP G GP P GP GP GP GP GP G KCTD13 KCNS2 23023127, 16082366 pred GP P G G G GP P GP G GP P P P GP GP G P P P GP GP P P G CNGA4 KCTD13 16082366 pred G G G G KCTD13 KCNK7 16082366 pred G KIAA0101 KCTD13 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KCTD13 KCNH3 16082366 pred GP GP G GP G GP G GP G P G P GP GP GP G P P P GP G P GP HCN1 KCTD13 16082366 pred G GP G P G P P P P GP P P P P P KCTD13 POLL 25402006 pred G KCTD13 KCTD7 16082366 pred P P P P P P P P P P P KCNJ13 KCTD13 16082366 pred P P P P P P P P GP P P P P P P P P P P KCNH2 KCTD13 16082366 pred GP GP G G G G G GP GP G GP GP GP G G GP G G GP G GP GP GP GP GP G GP GP G HLTF KCTD13 25402006 pred GP GP G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP GP G KCTD13 HCN2 16082366 pred G G G G G G KCTD13 KCTD14 23023127, 16082366 pred P P P P P P P P P P P P PTK2B KCTD13 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G P GP G G GP G GP GP G KCTD16 KCTD13 23023127, 16082366 pred G G G GP G P G P P GP P GP P P P KCNH1 KCTD13 16082366 pred P P P P P P P P DGKZ KCTD13 23023127 pred G G G G G GP G GP G G G G G G G G GP G GP G G G GP G G G GP GP G KCNJ6 KCTD13 16082366 pred P P G GP P P G P P P P GP P GP G P P P P P P P CDAN1 KCTD13 25402006 pred GP GP G G G G G G GP G GP GP GP G G GP G GP GP G GP GP GP G GP G GP GP G KCNH5 KCTD13 16082366 pred P G G GP P P G P P GP G G P P P P KCTD6 KCTD13 16082366 pred G GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP G G GP G GP GP G KCTD13 KCNK6 16082366 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G PRKCI KCTD13 23023127 pred GP GP G G G GP G G GP G GP G GP G G GP GP G GP G GP GP G G GP G GP GP G KCTD13 KCNJ14 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GADD45A KCTD13 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KCTD13 KCNH4 16082366 pred G G G G G G G G G G GRIA3 KCTD13 16082366 pred P GP G GP P P G P P P GP P P P P P P P P P KCTD13 POLDIP2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KCTD13 KCNK17 16082366 pred G G G G G G G GP G G G G G G G GP G G G G G G G G GP G GP GP G SOCS3 KCTD13 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G LIG1 KCTD13 25402006 pred GP P G G G GP P GP G P GP GP G G GP GP GP GP G GP GP P GP GP G GP GP G KCNQ4 KCTD13 16082366 pred P G GP G GP GP G P P P G GP GP G GP GP G G P G KCTD13 KCNK16 16082366 pred P P P GP GP G GP G P GP P P GP G GP P P P GP G GP GP G KCNQ2 KCTD13 16082366 pred G G GP G G G GP G G P GADD45B KCTD13 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G BCL6 KCTD13 23023127 pred G G G G G G G G G G G G G G G G G G G G GP G G G G G G G G CNGA1 KCTD13 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G RFC2 KCTD13 25402006 pred GP GP G G G GP G P GP G P G GP G G GP GP GP GP G GP GP GP G GP G GP GP KCTD13 KCNK4 16082366 pred KCTD13 KCNS3 16082366 pred GP P G G G GP G GP GP G GP GP GP G GP GP P GP G GP GP GP GP GP GP GP G KCNK1 KCTD13 16082366 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G KCTD13 KCNK9 16082366 pred G G G G KCNK10 KCTD13 16082366 pred P G G G GP G GP GP G GP G GP G GP GP G GP G GP P GP G GP GP P G KCTD13 KCND3 23023127 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G GP G P GP GP G GP G G GP G KCNJ8 KCTD13 16082366 pred GP GP G G GP GP GP GP G G GP G GP G P GP P GP GP G GP G KCNK2 KCTD13 16082366 pred G P P P P P KCTD13 CNGB3 16082366 pred G G G G G G G G G G G G G G G G G G G G G KCTD13 KCNG1 16082366 pred P P G P P P P P P P P P P GP P P P P P GP G KCTD13 KCNA7 16082366 pred G ANXA2 KCTD13 25402006 pred GP G G G G GP G G GP G GP GP GP G G G GP GP GP G GP GP G G G G GP GP G KCTD13 STMN3 23023127 pred G G G G G GP G G GP G GP G GP G G G GP G GP G G G G GP G G G G G SLIT2 KCTD13 23023127 pred GP GP G G G GP G GP GP G GP P GP G G GP GP GP GP G GP GP GP GP GP G GP GP G CNGA3 KCTD13 16082366 pred G KCNJ4 KCTD13 16082366 pred P G GP G P G P P P P GP P G P P P G P P P KCTD13 KCNH8 16082366 pred P G GP G GP G P P G P GP G G P G GP GP KCNK5 KCTD13 16082366 pred G GP G G GP G GP G GP G G G G G GP G G G G G G G G G GP G KCNJ1 KCTD13 16082366 pred P P P GP P P P P P P P KCTD13 KCNF1 16082366 pred P P G GP P P G P P P P GP P GP P P P P GP P P KCTD13 KCNJ16 16082366 pred P P G GP G P P G GP P G P GP GP G GP GP P GP GP GP FBXO45 KCTD13 23023127 pred GP GP G G G GP G G GP G GP G GP G G GP GP GP G G GP GP GP GP GP G GP GP G KCNC1 KCTD13 23023127, 16082366 pred G G G G GP G G G GP G G G G G G G KCNA10 KCTD13 16082366 pred P P P P P P P P P P P P P P P P P P P KCNA2 KCTD13 23023127, 16082366 pred G G GP G G P G P P P G GP GP P P G P P P G P GP P ERCC5 KCTD13 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G KCTD13 KCNQ5 16082366 pred P P G G G GP G P P G P P P GP P GP G P P KCNQ1 KCTD13 16082366 pred P GP P GP GP GP P GP G G GP P GP G GP P GP G GP P KCTD11 KCTD13 16082366 pred GP GP G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP P GP G GP P G CACNB4 KCTD13 16082366 pred P P G GP G P P G P P P P GP P P GP GP P P P P KCNV1 KCTD13 23023127, 16082366 pred G G G KCTD17 KCTD13 16082366 pred P G GP G P P G P P P P GP P P G P P P P GP RFC4 KCTD13 25402006 pred GP GP G G G GP G G GP G GP G GP G G GP GP G GP G GP GP GP G GP G GP GP G PARK2 KCTD13 23023127 pred P GP G GP G GP GP G GP P P G P GP GP P G P GP GP GP P GP G KCTD13 KCTD15 16082366 pred G G G G G G G GP G G G G G G G G G G G G G G G GP G G G G G KCTD13 KCNN2 16082366 pred P GP G GP G GP P G P GP P G P GP GP G P GP P GP P P P KCNJ5 KCTD13 16082366 pred P GP G G G GP G GP GP G GP GP P G G GP GP GP GP G GP P GP G GP G GP GP G KCTD13 POLD4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G HUS1 KCTD13 25402006 pred GP GP G G G P G GP GP G GP G G GP GP G GP G GP GP GP GP GP G GP GP G KCNG3 KCTD13 16082366 pred G G KCNC3 KCTD13 23023127, 16082366 pred P G G G GP G P G G GP GP G G P GP GP GP G P G GP P P GP G KCNT1 KCTD13 16082366 pred G G G P G P G P P P TFAP2A KCTD13 21836163 pred GP G G G G G G G G GP G G G G G G G G GP G G G G G G G KCNB1 KCTD13 23023127, 16082366 pred G G G G G GP G GP G G G G GP G G GP GP G G G GP GP G GP GP G G G G KCTD4 KCTD13 23023127 pred P P G GP G P P G P P P P GP P P G P P P P P P P KCTD13 KCTD5 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P49005 Q8WZ19 - 11593007 - X 2 P12004 Q8WZ19 - 11593007 - X 2 Q9H6L4 Q8WZ19 two hybrid 16189514 direct interaction X 2 Q96E35 Q8WZ19 two hybrid 25416956 direct interaction X 2 Q96E35 Q8WZ19 two hybrid 16189514 direct interaction X 2 Q8WZ19 O95251-2 two hybrid 16189514 direct interaction X 2 Q8WZ19 A0A024R475 affinity chromatography technology 21145461 physical association X 2 Q8WZ19 A0A024R475 affinity chromatography technology 19782033 physical association X 2 Q8WZ19 A0A024R475 two hybrid 25416956 direct interaction X 2 Q8WZ19 pull down 11593007 direct interaction X 2 Q8WZ19 Q15149 affinity chromatography technology 19615732 physical association X 2 Q8WZ19 A0A024RBJ2 affinity chromatography technology 19615732 physical association X 2 A4D0S4 Q8WZ19 affinity chromatography technology 19615732 physical association X 2 Q8WZ19 protein complementation assay 24561123 direct interaction X 2 Q8WZ19 affinity chromatography technology 24561123 physical association X 2 Q9UHP3 Q8WZ19 affinity chromatography technology 19615732 physical association X 2 Q6ZVK8 Q8WZ19 two hybrid 16189514 direct interaction X 2 Q8WZ19 P37231-3 two hybrid 16239304 direct interaction X 2 Q8WZ19 P37231-3 pull down 16239304 direct interaction X 2 Q8WZ19 Q8WZ19 two hybrid 25416956 direct interaction X 2 Q8WZ19 P78539 affinity chromatography technology 19615732 physical association X 2 Q8WZ19 Q8TBB1 two hybrid 16189514 direct interaction X 2 A0A024R324 Q8WZ19 affinity chromatography technology 19782033 physical association X 2 A0A024R324 Q8WZ19 pull down 19782033 direct interaction X 2 A0A024R324 Q8WZ19 enzymatic study 19782033 direct interaction X 2 P0CG48 Q8WZ19 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q8WZ19 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q8WZ19 affinity chromatography technology 21906983 physical association X 2 Q9NP79 Q8WZ19 two hybrid 16189514 direct interaction X 2 Q8WZ19 affinity chromatography technology 22902628 physical association X 2 Q8WZ19 affinity chromatography technology 22902628 physical association X 2 P12004 Q8WZ19 pull down 11593007 direct interaction X 2 P12004 Q8WZ19 far western blotting 11593007 direct interaction X 2 Q13829 Q8WZ19 two hybrid 25416956 direct interaction X 2 Q13829 Q8WZ19 affinity chromatography technology 19615732 physical association X 2 O95251 Q8WZ19 two hybrid 16189514 - X 2 O95251 Q8WZ19 two hybrid 16189514 - X 2 Q9H6L4 Q8WZ19 two hybrid 16189514 - X 2 Q9H6L4 Q8WZ19 two hybrid 16189514 - X 2 Q96E35 Q8WZ19 two hybrid 16189514 - X 2 Q96E35 Q8WZ19 two hybrid 16189514 - X 2 Q8TBB1-2 Q8WZ19 two hybrid 16189514 - X 2 Q8TBB1-2 Q8WZ19 two hybrid 16189514 - X 2 P49005 Q8WZ19 in vivo 11593007 - X 2 P49005 Q8WZ19 two hybrid 11593007 - X 2 P49005 Q8WZ19 in vitro 11593007 - X 2 P49005 Q8WZ19 in vitro 11593007 - X 2 P49005 Q8WZ19 two hybrid 11593007 - X 2 P49005 Q8WZ19 in vivo 11593007 - X 2 Q6ZVK8 Q8WZ19 two hybrid 16189514 - X 2 Q6ZVK8 Q8WZ19 two hybrid 16189514 - X 2 Q9NP79 Q8WZ19 two hybrid 16189514 - X 2 Q9NP79 Q8WZ19 two hybrid 16189514 - X 2 P12004 Q8WZ19 in vivo 11593007 - X 2 P12004 Q8WZ19 in vitro 11593007 - X 2 P12004 Q8WZ19 in vitro 11593007 - X 2 P12004 Q8WZ19 in vivo 11593007 - X 2 Q8WZ19 anti tag coimmunoprecipitation 19615732 physical association C 6 Q8WZ19 anti tag coimmunoprecipitation 19615732 physical association C 14 O95251 Q8WZ19 two hybrid pooling approach 16189514 physical association X 2 Q9H6L4 Q8WZ19 two hybrid pooling approach 16189514 physical association X 2 Q96E35 Q8WZ19 two hybrid pooling approach 16189514 physical association X 2 Q96E35 Q8WZ19 two hybrid prey pooling approach 25416956 physical association X 2 Q96E35 Q8WZ19 two hybrid array 25416956 physical association X 2 Q96E35 Q8WZ19 validated two hybrid 25416956 physical association X 2 Q8WZ19 A0A024R475 two hybrid prey pooling approach 25416956 physical association X 2 Q8WZ19 A0A024R475 two hybrid array 25416956 physical association X 2 Q8WZ19 A0A024R475 validated two hybrid 25416956 physical association X 2 Q6ZVK8 Q8WZ19 two hybrid pooling approach 16189514 physical association X 2 Q8WZ19 Q8TBB1 two hybrid pooling approach 16189514 physical association X 2 Q8WZ19 Q8WZ19 two hybrid array 25416956 physical association X 2 Q9NP79 Q8WZ19 two hybrid pooling approach 16189514 physical association X 2 Q13829 Q8WZ19 two hybrid prey pooling approach 25416956 physical association X 2 Q13829 Q8WZ19 two hybrid array 25416956 physical association X 2 Q13829 Q8WZ19 validated two hybrid 25416956 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B KCTD13 VTA1 MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0468(hprd)|(biogrid)|MI:0471(mint)|MI:0471(mint) UniProt_152093|HPRD_23409|BIOGRID_79248|MINT_37448|MINT_66629 unspecified role|-|prey|prey|prey unspecified role|-|bait|bait|bait KCTD13 ARMC7 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(intact)|MI:0471(mint)|MI:0471(mint) HPRD_23192|BIOGRID_78891|UniProt_151741|MINT_66304|MINT_37123 -|prey|unspecified role|prey|prey -|bait|unspecified role|bait|bait KCTD13 KCTD10 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100709|BIOGRID_120712 bait|bait prey|prey KCTD13 SPRTN MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22902628 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_207989|BIOGRID_208001 prey|bait bait|prey UBC KCTD13 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21890473,21906983 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_169020|BIOGRID_178339|BIOGRID_172893 bait|bait|bait prey|prey|prey KAT7 KCTD13 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(biogrid)|MI:0468(hprd)|(intact)|MI:0471(mint) MINT_68567|BIOGRID_80585|HPRD_22923|UniProt_153414|MINT_39305 bait|bait|-|unspecified role|bait prey|prey|-|unspecified role|prey KCTD13 USP25 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100690|BIOGRID_120858 prey|prey bait|bait SRPX KCTD13 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119908|UniProt_100709 prey|prey bait|bait PPARG KCTD13 MI:0018(two hybrid)|MI:0018(two hybrid) 16239304 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_214917|BIOGRID_214916 prey|bait bait|prey PCNA KCTD13 MI:0493(in vivo)|MI:0096(pull down)|MI:0096(pull down) 11593007 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_1321|BIOGRID_101282|BIOGRID_101281 -|bait|prey -|prey|bait LNX1 KCTD13 MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd) BIOGRID_80055|UniProt_152899|MINT_38446|MINT_67655|HPRD_23757 bait|unspecified role|bait|bait|- prey|unspecified role|prey|prey|- POLD2 KCTD13 MI:0493(in vivo)|MI:0096(pull down) 11593007 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_15991|BIOGRID_101280 -|prey -|bait NRF1 KCTD13 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_294941 bait prey PLEC KCTD13 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119657|UniProt_100709 prey|prey bait|bait NUDT18 KCTD13 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0468(hprd)|(biogrid)|MI:0471(mint)|(intact) MINT_67046|HPRD_23127|BIOGRID_79628|MINT_37863|UniProt_152474 bait|-|bait|bait|unspecified role prey|-|prey|prey|unspecified role ZMYND19 KCTD13 MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|(intact)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint) BIOGRID_80034|UniProt_152878|MINT_38400|HPRD_23755|MINT_67604 bait|unspecified role|bait|-|bait prey|unspecified role|prey|-|prey KCTD13 LAMB4 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100709|BIOGRID_120258 bait|bait prey|prey CUL3 KCTD13 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_202212 bait prey TNFAIP1 KCTD13 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119826|UniProt_100709 prey|prey bait|bait

PPI - HINT Gene A Gene B PMID Method Quality LAMB4 KCTD13 19615732,19615732 0004,0007 HT HSPA1L KCTD13 26186194 0004 HT SRPX KCTD13 19615732,19615732 0004,0007 HT CUL3 KCTD13 21145461,19782033,26100637 0004,0004,0004 HT,LC TNFAIP1 KCTD13 26186194,19615732,19615732 0004,0004,0007 HT PLEC KCTD13 19615732,19615732 0004,0007 HT Q59H94 KCTD13 26186194 0004 HT KCTD13 KCTD10 26186194,19615732,19615732 0004,0004,0007 HT KCTD13 USP25 19615732,19615732 0004,0007 HT KCTD13 HSPB8 26186194 0004 HT LAMB4 KCTD13 19615732,19615732 0004,0007 HT HSPA1L KCTD13 26186194 0004 HT SRPX KCTD13 19615732,19615732 0004,0007 HT CUL3 KCTD13 21145461 0004 HT TNFAIP1 KCTD13 26186194,19615732,19615732 0004,0004,0007 HT PLEC KCTD13 19615732,19615732 0004,0007 HT Q59H94 KCTD13 26186194 0004 HT KCTD13 KCTD10 26186194,19615732,19615732 0004,0004,0007 HT KCTD13 USP25 19615732,19615732 0004,0007 HT KCTD13 HSPB8 26186194 0004 HT CUL3 KCTD13 19782033,26100637 0004,0004 LC KAT7 KCTD13 16189514,16189514 0398,0018 HT ADRB2 KCTD13 24561123,24561123 0090,0004 LC PCNA KCTD13 11593007,11593007,11593007 0047,0096,0004 LC PPARG KCTD13 16239304,16239304 0096,0018 LC CRK KCTD13 25814554,25814554,25814554 0397,0018,1356 HT POLD2 KCTD13 11593007,11593007,11593007 0096,0004,0018 LC CUL3 KCTD13 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TNFAIP1 KCTD13 21516116,25416956,25416956,25416956,25416956 0018,0397,1112,0018,1356 HT NUDT18 KCTD13 16189514,16189514 0398,0018 HT LNX1 KCTD13 16189514,16189514 0398,0018 HT KCTD13 KCTD13 PDB_4UIJ,25416956,25416956 0114,0397,0018 LC,HT KCTD13 ZMYND19 16189514,25416956,25416956,25416956,16189514,25416956 0398,1112,0397,0018,0018,1356 HT KCTD13 ARHA 19782033,26100637,19782033,19782033 0096,0415,0004,0415 LC KCTD13 ARMC7 16189514,16189514 0398,0018 HT KCTD13 VTA1 16189514,16189514 0398,0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8WZ19 Q12354 KCTD13 Q12354 0.332 27107014 Q8WZ19 O94888 KCTD13 UBXN7 0.126 26389662 Q9H8Y8 Q8WZ19 GORASP2 KCTD13 0.236 unassigned1304 Q9NQT4 Q8WZ19 EXOSC5 KCTD13 0.236 unassigned1304 Q9UHP3 Q8WZ19 USP25 KCTD13 0.236 19615732 Q8WZ19 A4D0S4 KCTD13 LAMB4 0.236 19615732 Q8WZ19 P61586 KCTD13 RHOA 0.523 26100637,19782033 Q8WZ19 P78539 KCTD13 SRPX 0.236 19615732 Q8WZ19 Q15149 KCTD13 PLEC 0.236 19615732 Q8WZ19 Q16543 KCTD13 CDC37 0.236 unassigned1304 Q96E35 Q8WZ19 ZMYND19 KCTD13 0.702 25416956,16189514,unassigned1304 Q96HA8 Q8WZ19 WDYHV1 KCTD13 0.236 unassigned1304 Q8WZ19 P07550 KCTD13 ADRB2 0.286 24561123 Q8WZ19 O15160 KCTD13 POLR1C 0.236 unassigned1304 Q8WZ19 P25786 KCTD13 PSMA1 0.236 unassigned1304 Q8WZ19 Q13618 KCTD13 CUL3 0.712 25416956,21145461,unassigned1304,26100637 Q9H3F6 Q8WZ19 KCTD10 KCTD13 0.49 26186194,unassigned1304,19615732 Q8WZ19 Q13829 KCTD13 TNFAIP1 0.772 25416956,26186194,unassigned1304,19615732,21516116 Q8WZ19 Q8WZ19 KCTD13 KCTD13 0.787 25416956,27152988,unassigned1304 Q8WZ19 P37231 KCTD13 PPARG 0.523 16239304 Q9H040 Q8WZ19 SPRTN KCTD13 0.376 22902628 Q8WZ19 P49005 KCTD13 POLD2 0.309 11593007 Q8WZ19 P12004 KCTD13 PCNA 0.523 11593007 Q8WZ19 O95251 KCTD13 KAT7 0.286 16189514 Q8WZ19 P46108 KCTD13 CRK 0.454 25814554 Q8WZ19 P34931 KCTD13 HSPA1L 0.126 26186194 Q8WZ19 Q14315 KCTD13 FLNC 0.126 26186194 Q8WZ19 Q8TBB1 KCTD13 LNX1 0.454 16189514,unassigned1304 Q8WZ19 Q6ZVK8 KCTD13 NUDT18 0.286 16189514 Q9UJY1 Q8WZ19 HSPB8 KCTD13 0.126 26186194 Q9H6L4 Q8WZ19 ARMC7 KCTD13 0.454 16189514,unassigned1304 Q9NP79 Q8WZ19 VTA1 KCTD13 0.286 16189514 Q9UNN5 Q8WZ19 FAF1 KCTD13 0.126 26389662

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 LAMB4 KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database LYPLA1 KCTD13 MI:0362 inference MI:0461 interaction database UBXN7 KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database KAT7 KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database LYPLA2 KCTD13 MI:0362 inference MI:0461 interaction database ADRB2 KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database UBC KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database PCNA KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database ANXA7 KCTD13 MI:0362 inference MI:0461 interaction database HSPA1L KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database PPARG KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database ATP6V1A KCTD13 MI:0362 inference MI:0461 interaction database CRK KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database POLD2 KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database ANXA11 KCTD13 MI:0362 inference MI:0461 interaction database HMGA2 KCTD13 MI:0362 inference MI:0461 interaction database RHOA KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database YWHAG KCTD13 MI:0362 inference MI:0461 interaction database SRPX KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database YWHAH KCTD13 MI:0362 inference MI:0461 interaction database SMARCB1 KCTD13 MI:0362 inference MI:0461 interaction database CUL3 KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database TNFAIP1 KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database FLNC KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database PLEC KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database LYPLAL1 KCTD13 MI:0362 inference MI:0461 interaction database NUDT18 KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database LNX1 KCTD13 MI:0045 experimental interaction detection MI:0461 interaction database KCTD13 ZMYND19 MI:0045 experimental interaction detection MI:0461 interaction database KCTD13 SPRTN MI:0045 experimental interaction detection MI:0461 interaction database KCTD13 KCTD10 MI:0045 experimental interaction detection MI:0461 interaction database KCTD13 ARMC7 MI:0045 experimental interaction detection MI:0461 interaction database KCTD13 VTA1 MI:0045 experimental interaction detection MI:0461 interaction database KCTD13 USP25 MI:0045 experimental interaction detection MI:0461 interaction database KCTD13 HSPB8 MI:0045 experimental interaction detection MI:0461 interaction database KCTD13 FAF1 MI:0045 experimental interaction detection MI:0461 interaction database KCTD13 B9D1 MI:0362 inference MI:0461 interaction database