PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus VCPIP1 MED23 25281560 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G VCPIP1 WAC 23500464,21811234 biogrid exp G G G G G G G GP GP G GP G G GP G GP G G P G GP G G G GP G GP G VCPIP1 SSX2IP 26638075 biogrid,intact exp G G G G G G GP GP G GP G G G GP G G P G GP G G GP GP GP G VCPIP1 MAF1 26186194 biogrid exp G G G G G G G GP GP G GP G G G G GP G G P G GP G G G GP G GP G ABCC12 VCPIP1 19615732 biogrid,intact exp P P P P P P P P P G VCPIP1 KIF20B 26496610 biogrid,intact exp G G G G G G P GP P P G GP G G P P G G GP P G GP G DND1 VCPIP1 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G TTLL1 VCPIP1 26186194 biogrid exp G G G G G GP P G GP P G P G GP G G P G P G G GP GP G VCPIP1 BJ-HCC-24 tumor antigen, CDNA FLJ20030 fis, clone ADSU02156 19615732 intact exp VCPIP1 BTRC 25900982 biogrid exp G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G UBC VCPIP1 23827681,23500464 biogrid exp G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 NXF1 22658674 biogrid exp G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G PRMT2 VCPIP1 26186194 biogrid exp G G G G G G G GP GP G GP G G GP G GP G G P G GP G G GP GP G GP G UBXN2A VCPIP1 19615732 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G VAV2 VCPIP1 18654987 biogrid,intact exp G G G G G G G G GP G GP GP G G G GP G G P G GP G G GP G GP G HUWE1 VCPIP1 19615732 biogrid,intact exp G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G UBXN2B VCPIP1 19615732 biogrid,intact exp G G G G G G G G GP G GP G G G G GP G G G G G G G GP G GP G STIL VCPIP1 26638075 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G SMAD9 VCPIP1 15231748 biogrid,i2d,mint,intact exp G G G G G GP GP G GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 HRASLS5 26186194 biogrid exp G G G G G G G GP GP G GP G G P G GP G G P G P GP GP G GP G UBXN11 VCPIP1 18775313 biogrid exp G G G G G G G GP P G GP GP G G G GP G G P G GP G G GP GP G GP G VCPIP1 SPRTN 22902628 biogrid exp G G GP G G G G VCPIP1 MOV10 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G VCPIP1 CENPJ 26638075 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G LARP7 VCPIP1 22863883 biogrid exp G G G G G G G GP GP G GP GP G G G GP G G P G GP G G GP GP G GP G NTRK1 VCPIP1 25921289 biogrid exp G P P P P P P P P P P ARAF VCPIP1 20936779 i2d exp G G G G G G G G G G G G G G G G G G G G G G G G G G G VCP VCPIP1 23500464,21811234,24163436,19615732,12473691, 25402006, 21836163 hprd,biogrid,intact exp, ortho, pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 FAF1 18775313, 25402006 biogrid,intact exp, pred G G G G G G G GP GP G GP G G GP G GP G G P G GP G G GP GP G GP G UFD1L VCPIP1 19615732, 25402006 biogrid,intact exp, pred G G G G G G G GP GP G GP G G GP G GP G G P G GP G G GP GP G G G LGALS3BP VCPIP1 26496610, 25402006 biogrid,intact exp, pred G G G G G G G G GP G GP G G G G GP G G P G GP G G G GP G GP G FCHSD2 VCPIP1 18654987, 25402006 biogrid,intact exp, pred G G G G G G G GP GP G GP GP G G G GP G G P G GP G GP GP G GP G VCPIP1 ASPSCR1 18775313, 25402006 biogrid exp, pred G G G G G GP P G GP GP G GP G GP G P G GP G G GP GP G GP G VCPIP1 UBXN6 18775313, 25402006 biogrid,intact exp, pred G G G G G G P P G GP P P G GP G G P G P G GP GP GP G UBXN8 VCPIP1 18775313, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G VCPIP1 NSFL1C 18775313,12473691,19615732, 25402006, 21836163 biogrid,intact exp, pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G G GP G GP G STX5 VCPIP1 12473691, 21836163 hprd,biogrid exp, pred G G G G G G G G G G GP GP G GP G G G G P G GP G G G G G GP G SVIP VCPIP1 19615732, 25402006 biogrid,intact exp, pred G G G G G G G GP GP G GP GP G GP G GP G G P G P G G GP GP G GP G FAF2 VCPIP1 18775313,19615732, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G NPLOC4 VCPIP1 19615732, 25402006 biogrid,intact exp, pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G UBXN1 VCPIP1 18775313, 25402006 biogrid,intact exp, pred G G G G G G G G GP G GP GP G GP G GP G G P G GP G G GP GP G GP G YWHAE VCPIP1 ortho G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 ACTRT3 25402006 ortho, pred G IRAK1 VCPIP1 25402006 ortho, pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G G GP G GP G SCAMP2 VCPIP1 21836163 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G G GP G GP G STX6 VCPIP1 21836163 pred G G G G G G G G GP G GP GP G GP G GP G G P G GP G G G GP G GP G PSMF1 VCPIP1 21836163 pred G G G G G G G G GP G GP GP G GP G GP G G P G G G G G GP G GP G UBR1 VCPIP1 25402006 pred G G G G G G G GP GP G GP G G G G GP G G P G GP G G GP GP G GP G VCPIP1 UBXN10 25402006 pred G G G G G G G GP GP G GP GP G GP G G P G GP G G GP GP G GP G RINT1 VCPIP1 21836163 pred G G G G G G G GP GP G GP GP G G G GP G G P G GP G G GP GP G GP G PLEKHM2 VCPIP1 23023127 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G RGS14 VCPIP1 23023127 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G OPTN VCPIP1 23023127 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 STX18 21836163 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G UBXN7 VCPIP1 25402006 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G UBR4 VCPIP1 25402006 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G COG1 VCPIP1 23023127 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G GOLGA3 VCPIP1 21836163 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 SLC9A7 21836163 pred P P P P P P P P P P GOSR2 VCPIP1 21836163 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G PSMD2 VCPIP1 21836163 pred G G G G G G G GP GP G GP GP G G G GP G G P G GP G G GP GP G GP G SCAMP5 VCPIP1 21836163 pred G G G G G G G GP GP G GP G G G G G G G P G G G G GP G G GP G VCPIP1 ST6GALNAC1 21836163 pred GP P P G P GP P P G G GP G GP SOCS7 VCPIP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBR5 VCPIP1 25402006 pred G G G G G G G G GP G GP GP G GP G G G G G GP G G G G G GP G B3GALT4 VCPIP1 21836163 pred G G G G G G G GP G G GP G G G G G G G P G G G G GP G G G G VCPIP1 BET1L 21836163 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G G GP G GP G ATL2 VCPIP1 21836163 pred G G G G G G G GP GP G GP G G G G GP G G P G GP G G GP GP G GP G CD3D VCPIP1 25402006 pred G G G G G GP G GP GP G GP G G G G G G G GP G G G G GOLIM4 VCPIP1 21836163 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 DERL1 25402006 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 AMFR 25402006 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 ST6GALNAC2 21836163 pred G G G G G G G G G G G G G G G G UBE4B VCPIP1 25402006 pred G G G G G G G GP GP G GP G G GP G GP G G P G GP G G G GP G GP G VCPIP1 FAM118B 25402006 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G COG2 VCPIP1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SLC9A9 VCPIP1 21836163 pred G G G G G G G GP GP G GP G G GP G GP G G G GP G P GP G GP G VCPIP1 GORASP2 21836163 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G G GP G GP G VCPIP1 COG5 21836163 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 ERGIC3 21836163 pred G G G G G G G G GP G GP GP G GP G GP G G P G GP G G G GP G GP G RAB30 VCPIP1 21836163 pred G G G G G G G G GP G GP GP G G G P G G P G GP G G GP GP G GP G UBR2 VCPIP1 25402006 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G SCAMP1 VCPIP1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G RIMS1 VCPIP1 23023127 pred G G G G G GP G P P G G P G P G G GP GP GP G VCPIP1 PDF 21836163 pred P P P P P P P P P P P INSIG1 VCPIP1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G COPE VCPIP1 21836163 pred G G G G G G G G GP G GP GP G G G GP G G P G GP G G G GP G GP G VCPIP1 RNF19A 25402006 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G UBXN4 VCPIP1 25402006 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G VCPIP1 PLAA 25402006 pred G G G G G G G GP GP G GP G G GP G GP G G P G GP G G GP GP G GP G RAB14 VCPIP1 21836163 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q96JH7 A0A024RDR3 - 15231748 - X 2 Q96JH7 affinity chromatography technology 22902628 physical association X 2 Q96JH7 Q13190-4 affinity chromatography technology 12473691 physical association X 2 Q96JH7 Q13190-4 affinity chromatography technology 12473691 physical association X 2 Q96JH7 O15205 affinity chromatography technology 22797925 physical association X 2 Q96JH7 two hybrid 15231748 direct interaction X 2 Q96JH7 P55072 pull down 23500464 direct interaction X 2 Q96JH7 P55072 affinity chromatography technology 23500464 physical association X 2 Q96JH7 pull down 23500464 direct interaction X 2 Q96JH7 P55072 affinity chromatography technology 24163436 physical association X 2 Q96JH7 affinity chromatography technology 19615732 physical association X 2 Q96JH7 P55072 affinity chromatography technology 19615732 physical association X 2 Q96JH7 A0A024R8R4 affinity chromatography technology 19615732 physical association X 2 Q96JH7 Q96J65 affinity chromatography technology 19615732 physical association X 2 Q96JH7 Q14CS0 affinity chromatography technology 19615732 physical association X 2 Q96JH7 P68543 affinity chromatography technology 19615732 physical association X 2 Q96JH7 affinity chromatography technology 21811234 physical association X 2 Q96JH7 pull down 21811234 direct interaction X 2 Q96JH7 pull down 21811234 direct interaction X 2 Q96JH7 P55072 pull down 21811234 direct interaction X 2 Q96JH7 Q9UNN5 affinity chromatography technology 18775313 physical association X 2 Q96JH7 Q9BZV1 affinity chromatography technology 18775313 physical association X 2 Q96JH7 Q9BZE9-4 affinity chromatography technology 18775313 physical association X 2 Q96JH7 P52735 two hybrid 18654987 direct interaction X 2 P0CG48 Q96JH7 affinity chromatography technology 22505724 physical association X 2 P0CG48 Q96JH7 affinity chromatography technology 21963094 physical association X 2 P0CG48 Q96JH7 affinity chromatography technology 23000965 physical association X 2 P0CG48 Q96JH7 affinity chromatography technology 24816145 physical association X 2 P0CG48 Q96JH7 enzymatic study 23500464 direct interaction X 2 P0CG48 Q96JH7 enzymatic study 23827681 direct interaction X 2 P0CG48 Q96JH7 affinity chromatography technology 25147182 physical association X 2 P0CG48 Q96JH7 affinity chromatography technology 22118674 physical association X 2 P0CG48 Q96JH7 affinity chromatography technology 17370265 physical association X 2 P0CG48 Q96JH7 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q96JH7 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q96JH7 affinity chromatography technology 21906983 physical association X 2 Q96JH7 affinity chromatography technology 12473691 physical association X 2 Q96JH7 Q4G0J3 biochemical 22863883 colocalization X 2 Q96JH7 A0A024R9W5 affinity chromatography technology 19615732 physical association X 2 Q96JH7 Q96CS3 affinity chromatography technology 19615732 physical association X 2 Q96JH7 affinity chromatography technology 19615732 physical association X 2 Q96JH7 Q8NHG7 affinity chromatography technology 19615732 physical association X 2 Q96JH7 affinity chromatography technology 18775313 physical association X 2 Q96JH7 Q96CS3 affinity chromatography technology 18775313 physical association X 2 Q96JH7 O00124 affinity chromatography technology 18775313 physical association X 2 Q96JH7 Q5T124-3 affinity chromatography technology 18775313 physical association X 2 Q96JH7 O94868 two hybrid 18654987 direct interaction X 2 A0A024R539 Q96JH7 affinity chromatography technology 18775313 physical association X 2 Q96JH7 in vivo 12473691 - C 4 Q96JH7 in vivo 12473691 - C 4 Q96JH7 in vivo 12473691 - C 4 Q96JH7 in vivo 12473691 - C 4 Q96JH7 in vivo 12473691 - C 4 Q96JH7 in vivo 12473691 - C 4 Q96JH7 in vivo 12473691 - C 4 Q96JH7 in vivo 12473691 - C 4 Q96JH7 P55072 in vivo 12473691 - X 2 Q96JH7 P55072 in vitro 12473691 - X 2 Q96JH7 in vitro 12473691 - X 2 Q96JH7 in vivo 12473691 - X 2 Q96JH7 P55072 in vitro 12473691 - X 2 Q96JH7 P55072 in vivo 12473691 - X 2 Q96JH7 in vitro 12473691 - X 2 Q96JH7 in vivo 12473691 - X 2 Q96JH7 anti tag coimmunoprecipitation 19615732 physical association C 12 Q96JH7 anti tag coimmunoprecipitation 18775313 association C 5 Q96JH7 anti tag coimmunoprecipitation 18775313 association C 4 Q96JH7 O15198 two hybrid 15231748 physical association X 2 Q96JH7 P52735 two hybrid 18654987 physical association X 2 Q96JH7 anti tag coimmunoprecipitation 18775313 association C 5 Q96JH7 anti tag coimmunoprecipitation 18775313 association C 5 Q96JH7 anti tag coimmunoprecipitation 18775313 association C 4 Q96JH7 anti tag coimmunoprecipitation 18775313 association C 6 Q96JH7 anti tag coimmunoprecipitation 18775313 association C 6 Q96JH7 anti tag coimmunoprecipitation 18775313 association C 5 Q96JH7 O94868 two hybrid 18654987 physical association X 2 Q96JH7 Q7CFN3 two hybrid pooling approach 20711500 physical association X 2 Q8ZA76 Q96JH7 two hybrid pooling approach 20711500 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B SMAD9 VCPIP1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|MI:0471(mint) BIOGRID_258721|MINT_61442|UniProt_79110|MINT_32594 bait|bait|bait|bait prey|prey|prey|prey UBXN1 VCPIP1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact)|(intact) BIOGRID_148828|UniProt_183185|UniProt_168922|UniProt_97376 bait|bait|bait|bait prey|prey|prey|prey NPLOC4 VCPIP1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120546|UniProt_100685 prey|prey bait|bait UBXN2B VCPIP1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120814|UniProt_100685 prey|prey bait|bait UBD VCPIP1 MI:0004(affinity chromatography technology) 22797925 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_226390 bait prey FCHSD2 VCPIP1 MI:0018(two hybrid)|MI:0018(two hybrid) 18654987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_96838|BIOGRID_184884 bait|bait prey|prey VCP VCPIP1 MI:0493(in vivo)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12473691,19615732,21811234 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|(intact)|MI:0468(hprd)|(biogrid)|(biogrid) HPRD_40549|UniProt_100685|HPRD_8276|BIOGRID_119857|BIOGRID_141772 -|prey|-|prey|prey -|bait|-|bait|bait SVIP VCPIP1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100685|BIOGRID_120862 prey|prey bait|bait STX5 VCPIP1 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 12473691 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|- MI:0468(hprd)|(biogrid)|(biogrid)|MI:0468(hprd) HPRD_12149|BIOGRID_211984|BIOGRID_211985|HPRD_40549 -|bait|prey|- -|prey|bait|- UBXN11 VCPIP1 MI:0004(affinity chromatography technology) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148834 bait prey UBXN8 VCPIP1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact)|(intact) BIOGRID_148831|UniProt_183186|UniProt_168923|UniProt_97377 bait|bait|bait|bait prey|prey|prey|prey VAV2 VCPIP1 MI:0018(two hybrid)|MI:0018(two hybrid) 18654987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_96799|BIOGRID_184845 bait|bait prey|prey FAF2 VCPIP1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 18775313,19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|(biogrid)|(intact) UniProt_183183|UniProt_168920|UniProt_97374|BIOGRID_120289|BIOGRID_148818|UniProt_100685 bait|bait|bait|prey|bait|prey prey|prey|prey|bait|prey|bait VCPIP1 SPRTN MI:0004(affinity chromatography technology) 22902628 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_207985 prey bait UBC VCPIP1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 17370265,21139048,21890473,21906983,21963094,22118674,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_179455|BIOGRID_268298|BIOGRID_225178|BIOGRID_161311|BIOGRID_264589|BIOGRID_170214|BIOGRID_174337|BIOGRID_160650 bait|bait|bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey|prey|prey ABCC12 VCPIP1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120779|UniProt_100685 prey|prey bait|bait UFD1L VCPIP1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100685|BIOGRID_119842 prey|prey bait|bait UBXN2A VCPIP1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100685|BIOGRID_120832 prey|prey bait|bait HUWE1 VCPIP1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120121|UniProt_100685 prey|prey bait|bait VCPIP1 WAC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21811234 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_141769|BIOGRID_141771|BIOGRID_141767 prey|bait|prey bait|prey|bait LARP7 VCPIP1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_300888 prey bait VCPIP1 NSFL1C MI:0493(in vivo)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12473691,18775313,19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(intact)|(biogrid)|(biogrid)|(biogrid) HPRD_40549|UniProt_100685|BIOGRID_211983|BIOGRID_120571|BIOGRID_148814 -|bait|prey|bait|prey -|prey|bait|prey|bait VCPIP1 FAF1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid) UniProt_168918|UniProt_183181|UniProt_97372|BIOGRID_148822 prey|prey|prey|prey bait|bait|bait|bait VCPIP1 ASPSCR1 MI:0004(affinity chromatography technology) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148842 prey bait VCPIP1 UBXN6 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact)|(intact) BIOGRID_148836|UniProt_183188|UniProt_168925|UniProt_97379 prey|prey|prey|prey bait|bait|bait|bait

PPI - HINT Gene A Gene B PMID Method Quality TTLL1 VCPIP1 26186194 0004 HT UBC VCPIP1 17370265,22118674 0004,0004 LC VCP VCPIP1 19615732,19615732,21811234 0004,0007,0096 HT,LC PRMT2 VCPIP1 26186194 0004 HT UBXN2A VCPIP1 19615732,19615732,26389662 0004,0007,0004 HT,LC LGALS3BP VCPIP1 26496610,26496610 0007,0004 HT UBXN2B VCPIP1 19615732,19615732,26389662 0004,0007,0004 HT,LC STIL VCPIP1 26638075,26638075 1314,1313 HT LARP7 VCPIP1 22863883 0401 HT HUWE1 VCPIP1 19615732,19615732 0004,0007 HT DND1 VCPIP1 26186194 0004 HT SVIP VCPIP1 19615732,19615732 0004,0007 HT NPLOC4 VCPIP1 19615732,19615732,26389662 0004,0007,0004 HT,LC UFD1L VCPIP1 19615732,19615732,26389662 0004,0007,0004 HT,LC FAF2 VCPIP1 19615732,19615732,18775313,18775313 0004,0007,0004,0007 HT,LC ABCC12 VCPIP1 19615732,19615732 0004,0007 HT VCPIP1 HRASLS5 26186194 0004 HT VCPIP1 KIF20B 26496610,26496610 0007,0004 HT VCPIP1 WAC 21811234,21811234,23500464 0096,0004,0096 LC VCPIP1 MAF1 26186194 0004 HT VCPIP1 CENPJ 26638075,26638075 1314,1313 HT VCPIP1 Q9NXW1 19615732 0007 HT VCPIP1 NSFL1C 12473691,19615732,19615732,18775313,26389662 0004,0004,0007,0004,0004 LC,HT VCPIP1 SSX2IP 26638075,26638075 1314,1313 HT VCPIP1 HEL-S-70 24163436,23500464,19615732,26389662,21811234,23500464 0004,0004,0004,0004,0096,0096 LC,HT TTLL1 VCPIP1 26186194 0004 HT VCP VCPIP1 19615732,19615732 0004,0007 HT PRMT2 VCPIP1 26186194 0004 HT UBXN2A VCPIP1 19615732,19615732 0004,0007 HT LGALS3BP VCPIP1 26496610,26496610 0007,0004 HT UBXN2B VCPIP1 19615732,19615732 0004,0007 HT STIL VCPIP1 26638075,26638075 1314,1313 HT LARP7 VCPIP1 22863883 0401 HT HUWE1 VCPIP1 19615732,19615732 0004,0007 HT DND1 VCPIP1 26186194 0004 HT SVIP VCPIP1 19615732,19615732 0004,0007 HT NPLOC4 VCPIP1 19615732,19615732 0004,0007 HT UFD1L VCPIP1 19615732,19615732 0004,0007 HT FAF2 VCPIP1 19615732,19615732 0004,0007 HT ABCC12 VCPIP1 19615732,19615732 0004,0007 HT VCPIP1 HRASLS5 26186194 0004 HT VCPIP1 KIF20B 26496610,26496610 0007,0004 HT VCPIP1 MAF1 26186194 0004 HT VCPIP1 CENPJ 26638075,26638075 1314,1313 HT VCPIP1 Q9NXW1 19615732 0007 HT VCPIP1 NSFL1C 19615732,19615732 0004,0007 HT VCPIP1 SSX2IP 26638075,26638075 1314,1313 HT VCPIP1 HEL-S-70 19615732 0004 HT UBC VCPIP1 17370265,22118674 0004,0004 LC VCP VCPIP1 21811234 0096 LC UBXN2A VCPIP1 26389662 0004 LC UBXN2B VCPIP1 26389662 0004 LC NPLOC4 VCPIP1 26389662 0004 LC UFD1L VCPIP1 26389662 0004 LC FAF2 VCPIP1 18775313,18775313 0004,0007 LC VCPIP1 WAC 21811234,21811234,23500464 0096,0004,0096 LC VCPIP1 NSFL1C 12473691,18775313,26389662 0004,0004,0004 LC VCPIP1 HEL-S-70 24163436,23500464,26389662,21811234,23500464 0004,0004,0004,0096,0096 LC SMAD9 VCPIP1 15231748 0018 HT FCHSD2 VCPIP1 18654987 0018 HT UBC VCPIP1 23827681,23500464 0415,0415 LC VAV2 VCPIP1 18654987 0018 HT LARP7 VCPIP1 22863883 0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q96JH7 Q5T124 VCPIP1 UBXN11 0.126 18775313 Q96JH7 O35987 VCPIP1 NSFL1C 0.126 18775313 Q96JH7 Q8IYX4 VCPIP1 DND1 0.126 26186194 Q9HCE1 Q96JH7 MOV10 VCPIP1 0.126 22658674 Q96JH7 Q8R512 VCPIP1 UBXN11 0.126 18775313 Q9H040 Q96JH7 SPRTN VCPIP1 0.21 22902628 Q9H063 Q96JH7 MAF1 VCPIP1 0.126 26186194 Q96JH7 Q8TAT6 VCPIP1 NPLOC4 0.332 19615732,26389662 Q9Y2D8 Q96JH7 SSX2IP VCPIP1 0.126 26638075 Q9Y297 Q96JH7 BTRC VCPIP1 0.126 25900982 Q96JH7 O94888 VCPIP1 UBXN7 0.126 26389662 Q96JH7 P04629 VCPIP1 NTRK1 0.126 25921289 Q96JH7 O95922 VCPIP1 TTLL1 0.126 26186194 Q9HC77 Q96JH7 CENPJ VCPIP1 0.236 26638075 Q9UNN5 Q96JH7 FAF1 VCPIP1 0.236 18775313 Q96Q89 Q96JH7 KIF20B VCPIP1 0.236 26496610 Q96JH7 Q96CS3 VCPIP1 FAF2 0.416 18775313,19615732 Q96JH7 P0CG48 VCPIP1 UBC 0.523 23827681,23500464 Q96JH7 Q7Z6Z7 VCPIP1 HUWE1 0.236 19615732 Q96JH7 Q8NHG7 VCPIP1 SVIP 0.236 19615732 Q9BTA9 Q96JH7 WAC VCPIP1 0.74 21811234,23500464 Q96JH7 Q96J65 VCPIP1 ABCC12 0.236 19615732 Q9UNZ2 Q96JH7 NSFL1C VCPIP1 0.539 12473691,19615732,18775313,26389662 Q9BZV1 Q96JH7 UBXN6 VCPIP1 0.236 18775313 Q96JH7 Q15468 VCPIP1 STIL 0.236 26638075 Q96JH7 O15198 VCPIP1 SMAD9 0.332 15231748 Q96JH7 Q08380 VCPIP1 LGALS3BP 0.236 26496610 Q96JH7 Q04323 VCPIP1 UBXN1 0.236 18775313 Q96JH7 O00124 VCPIP1 UBXN8 0.236 18775313 Q96JH7 Q92890 VCPIP1 UFD1L 0.332 19615732,26389662 Q96JH7 Q8ZA76 VCPIP1 GLGX 0.126 20711500 Q96JH7 O94868 VCPIP1 FCHSD2 0.454 18654987 Q96JH7 P52735 VCPIP1 VAV2 0.332 18654987 Q96JH7 Q13190 VCPIP1 STX5 0.376 12473691 Q96JH7 Q4G0J3 VCPIP1 LARP7 0.081 22863883 Q96JH7 Q7CFN3 VCPIP1 Q7CFN3 0.126 20711500 Q9NXW1 Q96JH7 Q9NXW1 VCPIP1 0.126 19615732 Q96KN8 Q96JH7 HRASLS5 VCPIP1 0.126 26186194 Q9BZE9 Q96JH7 ASPSCR1 VCPIP1 0.126 18775313 Q9ES54 Q96JH7 NPLOC4 VCPIP1 0.126 18775313 Q9UBU9 Q96JH7 NXF1 VCPIP1 0.126 22658674 Q96JH7 Q14CS0 VCPIP1 UBXN2B 0.332 19615732,26389662 Q96JH7 P68543 VCPIP1 UBXN2A 0.332 19615732,26389662 Q96JH7 P55072 VCPIP1 VCP 0.801 19615732,21811234,26389662,24163436,23500464 Q96JH7 P55345 VCPIP1 PRMT2 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 UBXN8 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database SMAD9 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database UBD VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database NPHP4 VCPIP1 MI:0362 inference MI:0461 interaction database FCHSD2 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database UBXN7 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database TTLL1 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database UBC VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database IRAK1 VCPIP1 MI:0362 inference MI:0461 interaction database VAV2 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database VCP VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database PRMT2 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database RAB38 VCPIP1 MI:0362 inference MI:0461 interaction database PFN3 VCPIP1 MI:0362 inference MI:0461 interaction database UBXN2A VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database UBXN1 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database LGALS3BP VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database STX5 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database RAB32 VCPIP1 MI:0362 inference MI:0461 interaction database UBXN2B VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database STIL VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database RAB30 VCPIP1 MI:0362 inference MI:0461 interaction database UBXN11 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database CEP162 VCPIP1 MI:0362 inference MI:0461 interaction database KIF21A VCPIP1 MI:0362 inference MI:0461 interaction database HUWE1 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database KIAA2013 VCPIP1 MI:0362 inference MI:0461 interaction database DND1 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database SVIP VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database NPLOC4 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database ALMS1 VCPIP1 MI:0362 inference MI:0461 interaction database CCHCR1 VCPIP1 MI:0362 inference MI:0461 interaction database UFD1L VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database FAF2 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database ABCC12 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 HRASLS5 MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 KIF20B MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 WAC MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 ACTRT3 MI:0362 inference MI:0461 interaction database VCPIP1 ASPSCR1 MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 UBXN6 MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 SPRTN MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 MAF1 MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 CENPJ MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 MOV10 MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 NXF1 MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 MED23 MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 FAF1 MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 NSFL1C MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 BTRC MI:0045 experimental interaction detection MI:0461 interaction database VCPIP1 SSX2IP MI:0045 experimental interaction detection MI:0461 interaction database