Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 11 5537102 5537102 + Silent SNP G G A TCGA-G2-AA3B-01A-11D-A391-08 TCGA-G2-AA3B-10A-01D-A394-08 g.chr11:5537102G>A c.570C>T c.(568-570)ttC>ttT p.F190F BLCA 11 5537230 5537230 + Silent SNP G G A TCGA-XF-A9T0-01A-11D-A391-08 TCGA-XF-A9T0-10A-01D-A394-08 g.chr11:5537230G>A c.442C>T c.(442-444)Ctg>Ttg p.L148L BLCA 11 5537271 5537271 + Missense_Mutation SNP C C G TCGA-FD-A3SO-01A-11D-A22Z-08 TCGA-FD-A3SO-10A-01D-A22Z-08 g.chr11:5537271C>G c.401G>C c.(400-402)aGa>aCa p.R134T BLCA 11 5537402 5537402 + Silent SNP G G A TCGA-KQ-A41P-01A-12D-A339-08 TCGA-KQ-A41P-10F-01D-A339-08 g.chr11:5537402G>A c.270C>T c.(268-270)atC>atT p.I90I BRCA 11 5537479 5537479 + Missense_Mutation SNP A A G TCGA-B6-A400-01A-11D-A23C-09 TCGA-B6-A400-10A-01D-A23C-09 g.chr11:5537479A>G c.193T>C c.(193-195)Tgc>Cgc p.C65R CESC 11 5536549 5536549 + Missense_Mutation SNP G G A TCGA-LP-A4AW-01A-11D-A243-09 TCGA-LP-A4AW-10A-01D-A243-09 g.chr11:5536549G>A c.1123C>T c.(1123-1125)Cgg>Tgg p.R375W CESC 11 5537435 5537435 + Silent SNP G G C TCGA-JW-A5VL-01A-11D-A28B-09 TCGA-JW-A5VL-10A-01D-A28E-09 g.chr11:5537435G>C c.237C>G c.(235-237)ctC>ctG p.L79L CHOL 11 5537616 5537616 + Missense_Mutation SNP C C T TCGA-W5-AA2Q-01A-11D-A417-09 TCGA-W5-AA2Q-10A-01D-A41A-09 g.chr11:5537616C>T c.56G>A c.(55-57)gGt>gAt p.G19D COAD 11 5536505 5536505 + Silent SNP G G A TCGA-D5-6540-01A-11D-1719-10 TCGA-D5-6540-10A-01D-1719-10 g.chr11:5536505G>A c.1167C>T c.(1165-1167)acC>acT p.T389T COAD 11 5536581 5536581 + Missense_Mutation SNP G G T TCGA-G4-6299-01A-11D-1771-10 TCGA-G4-6299-10A-01D-1771-10 g.chr11:5536581G>T c.1091C>A c.(1090-1092)tCc>tAc p.S364Y COAD 11 5536602 5536602 + Missense_Mutation SNP T T C TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr11:5536602T>C c.1070A>G c.(1069-1071)aAa>aGa p.K357R COAD 11 5536650 5536650 + Missense_Mutation SNP G G A TCGA-CK-4948-01B-11D-1650-10 TCGA-CK-4948-10A-01D-1650-10 g.chr11:5536650G>A c.1022C>T c.(1021-1023)tCa>tTa p.S341L COAD 11 5536733 5536733 + Silent SNP T T C TCGA-G4-6625-01A-21D-1771-10 TCGA-G4-6625-11A-01D-1771-10 g.chr11:5536733T>C c.939A>G c.(937-939)ccA>ccG p.P313P COAD 11 5536740 5536740 + Frame_Shift_Del DEL G G - TCGA-F4-6570-01A-11D-1771-10 TCGA-F4-6570-10A-01D-1771-10 g.chr11:5536740delG c.932delC c.(931-933)ccafs p.P315fs COAD 11 5536745 5536745 + Silent SNP T T C TCGA-AA-3947-01A-01W-0995-10 TCGA-AA-3947-10A-01W-0995-10 g.chr11:5536745T>C c.927A>G c.(925-927)tcA>tcG p.S309S COAD 11 5536800 5536800 + Missense_Mutation SNP C C T TCGA-F4-6460-01A-11D-1771-10 TCGA-F4-6460-10B-01D-1771-10 g.chr11:5536800C>T c.872G>A c.(871-873)gGa>gAa p.G291E COAD 11 5536838 5536838 + Silent SNP A A G TCGA-DM-A1HB-01A-21D-A183-10 TCGA-DM-A1HB-10A-01D-A183-10 g.chr11:5536838A>G c.834T>C c.(832-834)aaT>aaC p.N278N COAD 11 5536852 5536852 + Missense_Mutation SNP A A C TCGA-AA-3516-01A-02W-0833-10 TCGA-AA-3516-10A-01W-0833-10 g.chr11:5536852A>C c.820T>G c.(820-822)Tat>Gat p.Y274D COAD 11 5536870 5536870 + Missense_Mutation SNP T T A TCGA-D5-6533-01A-11D-1719-10 TCGA-D5-6533-10A-01D-1719-10 g.chr11:5536870T>A c.802A>T c.(802-804)Aat>Tat p.N268Y COAD 11 5537069 5537069 + Silent SNP C C T TCGA-AA-3715-01A-01W-0900-09 TCGA-AA-3715-10A-01W-0900-09 g.chr11:5537069C>T c.603G>A c.(601-603)acG>acA p.T201T COAD 11 5537077 5537077 + Missense_Mutation SNP G G C TCGA-AA-3956-01A-02W-0995-10 TCGA-AA-3956-10A-01W-0995-10 g.chr11:5537077G>C c.595C>G c.(595-597)Cta>Gta p.L199V COAD 11 5537083 5537083 + Nonsense_Mutation SNP C C A TCGA-AA-3977-01A-01W-0995-10 TCGA-AA-3977-10A-01W-0999-10 g.chr11:5537083C>A c.589G>T c.(589-591)Gaa>Taa p.E197* COADREAD 11 5536505 5536505 + Silent SNP G G A TCGA-D5-6540-01A-11D-1719-10 TCGA-D5-6540-10A-01D-1719-10 g.chr11:5536505G>A c.1167C>T c.(1165-1167)acC>acT p.T389T COADREAD 11 5536581 5536581 + Missense_Mutation SNP G G T TCGA-G4-6299-01A-11D-1771-10 TCGA-G4-6299-10A-01D-1771-10 g.chr11:5536581G>T c.1091C>A c.(1090-1092)tCc>tAc p.S364Y COADREAD 11 5536602 5536602 + Missense_Mutation SNP T T C TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr11:5536602T>C c.1070A>G c.(1069-1071)aAa>aGa p.K357R COADREAD 11 5536650 5536650 + Missense_Mutation SNP G G A TCGA-CK-4948-01B-11D-1650-10 TCGA-CK-4948-10A-01D-1650-10 g.chr11:5536650G>A c.1022C>T c.(1021-1023)tCa>tTa p.S341L COADREAD 11 5536733 5536733 + Silent SNP T T C TCGA-CI-6619-01B-11D-1826-10 TCGA-CI-6619-10A-01D-1826-10 g.chr11:5536733T>C c.939A>G c.(937-939)ccA>ccG p.P313P COADREAD 11 5536733 5536733 + Silent SNP T T C TCGA-G4-6625-01A-21D-1771-10 TCGA-G4-6625-11A-01D-1771-10 g.chr11:5536733T>C c.939A>G c.(937-939)ccA>ccG p.P313P COADREAD 11 5536740 5536740 + Frame_Shift_Del DEL G G - TCGA-F4-6570-01A-11D-1771-10 TCGA-F4-6570-10A-01D-1771-10 g.chr11:5536740delG c.932delC c.(931-933)ccafs p.P315fs COADREAD 11 5536745 5536745 + Silent SNP T T C TCGA-AA-3947-01A-01W-0995-10 TCGA-AA-3947-10A-01W-0995-10 g.chr11:5536745T>C c.927A>G c.(925-927)tcA>tcG p.S309S COADREAD 11 5536800 5536800 + Missense_Mutation SNP C C T TCGA-F4-6460-01A-11D-1771-10 TCGA-F4-6460-10B-01D-1771-10 g.chr11:5536800C>T c.872G>A c.(871-873)gGa>gAa p.G291E COADREAD 11 5536838 5536838 + Silent SNP A A G TCGA-DM-A1HB-01A-21D-A183-10 TCGA-DM-A1HB-10A-01D-A183-10 g.chr11:5536838A>G c.834T>C c.(832-834)aaT>aaC p.N278N COADREAD 11 5536852 5536852 + Missense_Mutation SNP A A C TCGA-AA-3516-01A-02W-0833-10 TCGA-AA-3516-10A-01W-0833-10 g.chr11:5536852A>C c.820T>G c.(820-822)Tat>Gat p.Y274D COADREAD 11 5536870 5536870 + Missense_Mutation SNP T T A TCGA-D5-6533-01A-11D-1719-10 TCGA-D5-6533-10A-01D-1719-10 g.chr11:5536870T>A c.802A>T c.(802-804)Aat>Tat p.N268Y COADREAD 11 5536943 5536943 + Missense_Mutation SNP T T G TCGA-AG-3600-01A-01W-0833-10 TCGA-AG-3600-10A-01W-0833-10 g.chr11:5536943T>G c.729A>C c.(727-729)caA>caC p.Q243H COADREAD 11 5537034 5537034 + Missense_Mutation SNP C C T TCGA-AG-3581-01A-01W-0831-10 TCGA-AG-3581-10A-01W-0831-10 g.chr11:5537034C>T c.638G>A c.(637-639)cGc>cAc p.R213H COADREAD 11 5537069 5537069 + Silent SNP C C T TCGA-AA-3715-01A-01W-0900-09 TCGA-AA-3715-10A-01W-0900-09 g.chr11:5537069C>T c.603G>A c.(601-603)acG>acA p.T201T COADREAD 11 5537077 5537077 + Missense_Mutation SNP G G C TCGA-AA-3956-01A-02W-0995-10 TCGA-AA-3956-10A-01W-0995-10 g.chr11:5537077G>C c.595C>G c.(595-597)Cta>Gta p.L199V COADREAD 11 5537083 5537083 + Nonsense_Mutation SNP C C A TCGA-AA-3977-01A-01W-0995-10 TCGA-AA-3977-10A-01W-0999-10 g.chr11:5537083C>A c.589G>T c.(589-591)Gaa>Taa p.E197* ESCA 11 5536298 5536298 + Missense_Mutation SNP C C A TCGA-L5-A4OW-01A-11D-A28B-09 TCGA-L5-A4OW-11A-11D-A28E-09 g.chr11:5536298C>A c.1374G>T c.(1372-1374)caG>caT p.Q458H ESCA 11 5537115 5537115 + Missense_Mutation SNP G G T TCGA-XP-A8T6-01A-11D-A36J-09 TCGA-XP-A8T6-10A-01D-A36M-09 g.chr11:5537115G>T c.557C>A c.(556-558)tCc>tAc p.S186Y ESCA 11 5537319 5537319 + Missense_Mutation SNP G G A TCGA-L5-A4OT-01A-11D-A28B-09 TCGA-L5-A4OT-11A-11D-A28E-09 g.chr11:5537319G>A c.353C>T c.(352-354)aCg>aTg p.T118M ESCA 11 5537370 5537370 + Missense_Mutation SNP T T G TCGA-IC-A6RE-01A-11D-A33E-09 TCGA-IC-A6RE-10A-01D-A33H-09 g.chr11:5537370T>G c.302A>C c.(301-303)aAg>aCg p.K101T ESCA 11 5537601 5537601 + Missense_Mutation SNP T T A TCGA-L5-A8NI-01A-11D-A37C-09 TCGA-L5-A8NI-11A-11D-A37F-09 g.chr11:5537601T>A c.71A>T c.(70-72)aAa>aTa p.K24I GBMLGG 11 5537069 5537069 + Silent SNP C C T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr11:5537069C>T c.603G>A c.(601-603)acG>acA p.T201T HNSC 11 5537120 5537120 + Silent SNP A A T TCGA-QK-A8ZB-01A-11D-A391-08 TCGA-QK-A8ZB-10A-01D-A394-08 g.chr11:5537120A>T c.552T>A c.(550-552)ctT>ctA p.L184L HNSC 11 5537198 5537198 + Missense_Mutation SNP T T A TCGA-CV-7440-01A-11D-2129-08 TCGA-CV-7440-10A-01D-2129-08 g.chr11:5537198T>A c.474A>T c.(472-474)aaA>aaT p.K158N HNSC 11 5537243 5537243 + Missense_Mutation SNP T T G TCGA-BA-A8YP-01A-11D-A391-08 TCGA-BA-A8YP-10A-01D-A394-08 g.chr11:5537243T>G c.429A>C c.(427-429)caA>caC p.Q143H HNSC 11 5537461 5537461 + Missense_Mutation SNP C C A TCGA-CV-A45W-01A-11D-A25D-08 TCGA-CV-A45W-10A-01D-A25E-08 g.chr11:5537461C>A c.211G>T c.(211-213)Gtg>Ttg p.V71L KIPAN 11 5537653 5537653 + Nonsense_Mutation SNP G G A TCGA-B0-5077-01A-01D-1462-08 TCGA-B0-5077-11A-01D-1462-08 g.chr11:5537653G>A c.19C>T c.(19-21)Cga>Tga p.R7* KIRC 11 5537653 5537653 + Nonsense_Mutation SNP G G A TCGA-B0-5077-01A-01D-1462-08 TCGA-B0-5077-11A-01D-1462-08 g.chr11:5537653G>A c.19C>T c.(19-21)Cga>Tga p.R7* LGG 11 5537069 5537069 + Silent SNP C C T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr11:5537069C>T c.603G>A c.(601-603)acG>acA p.T201T LIHC 11 5537290 5537290 + Missense_Mutation SNP T T A TCGA-G3-AAV3-01A-11D-A36X-10 TCGA-G3-AAV3-10A-01D-A370-10 g.chr11:5537290T>A c.382A>T c.(382-384)Acc>Tcc p.T128S LIHC 11 5537570 5537570 + Silent SNP T T A TCGA-ED-A459-01A-11D-A25V-10 TCGA-ED-A459-10A-01D-A25V-10 g.chr11:5537570T>A c.102A>T c.(100-102)atA>atT p.I34I LIHC 11 5537631 5537631 + Missense_Mutation SNP C C G TCGA-DD-AAED-01A-12D-A40R-10 TCGA-DD-AAED-10A-01D-A40U-10 g.chr11:5537631C>G c.41G>C c.(40-42)aGt>aCt p.S14T LUAD 11 5536432 5536432 + Missense_Mutation SNP G G T TCGA-97-A4M7-01A-11D-A24P-08 TCGA-97-A4M7-10A-01D-A24P-08 g.chr11:5536432G>T c.1240C>A c.(1240-1242)Ctc>Atc p.L414I LUAD 11 5536578 5536578 + Missense_Mutation SNP G G T TCGA-NJ-A4YP-01A-11D-A25L-08 TCGA-NJ-A4YP-10A-01D-A25L-08 g.chr11:5536578G>T c.1094C>A c.(1093-1095)aCc>aAc p.T365N LUAD 11 5536678 5536678 + Missense_Mutation SNP T T G TCGA-05-5715-01A-01D-1625-08 TCGA-05-5715-10A-01D-1625-08 g.chr11:5536678T>G c.994A>C c.(994-996)Atc>Ctc p.I332L LUAD 11 5536688 5536688 + Silent SNP T T C TCGA-55-8506-01A-11D-2393-08 TCGA-55-8506-10A-01D-2393-08 g.chr11:5536688T>C c.984A>G c.(982-984)gcA>gcG p.A328A LUAD 11 5536898 5536898 + Silent SNP C C A TCGA-MN-A4N4-01A-12D-A24P-08 TCGA-MN-A4N4-10A-01D-A24P-08 g.chr11:5536898C>A c.774G>T c.(772-774)ctG>ctT p.L258L LUAD 11 5536962 5536962 + Missense_Mutation SNP T T C TCGA-17-Z051-01A-01W-0747-08 TCGA-17-Z051-11A-01W-0747-08 g.chr11:5536962T>C c.710A>G c.(709-711)gAg>gGg p.E237G LUAD 11 5537024 5537024 + Silent SNP A A T TCGA-55-8506-01A-11D-2393-08 TCGA-55-8506-10A-01D-2393-08 g.chr11:5537024A>T c.648T>A c.(646-648)ctT>ctA p.L216L LUAD 11 5537381 5537381 + Nonsense_Mutation SNP G G C TCGA-69-7980-01A-11D-2184-08 TCGA-69-7980-10A-01D-2184-08 g.chr11:5537381G>C c.291C>G c.(289-291)taC>taG p.Y97* LUAD 11 5537461 5537461 + Missense_Mutation SNP C C A TCGA-75-5126-01A-01D-1753-08 TCGA-75-5126-10A-01D-1753-08 g.chr11:5537461C>A c.211G>T c.(211-213)Gtg>Ttg p.V71L LUAD 11 5537474 5537474 + Silent SNP C C T TCGA-44-7670-01A-11D-2063-08 TCGA-44-7670-10A-01D-2063-08 g.chr11:5537474C>T c.198G>A c.(196-198)caG>caA p.Q66Q LUAD 11 5537492 5537492 + Missense_Mutation SNP C C A TCGA-73-4668-01A-01D-1265-08 TCGA-73-4668-11A-01D-1265-08 g.chr11:5537492C>A c.180G>T c.(178-180)ttG>ttT p.L60F LUAD 11 5537572 5537572 + Missense_Mutation SNP T T G TCGA-17-Z000-01A-01W-0746-08 TCGA-17-Z000-11A-01W-0746-08 g.chr11:5537572T>G c.100A>C c.(100-102)Ata>Cta p.I34L LUAD 11 5537603 5537603 + Missense_Mutation SNP G G T TCGA-49-6743-01A-11D-1855-08 TCGA-49-6743-11A-01D-1855-08 g.chr11:5537603G>T c.69C>A c.(67-69)gaC>gaA p.D23E LUSC 11 5536292 5536292 + Silent SNP C C T TCGA-66-2773-01A-01D-1267-08 TCGA-66-2773-11A-01D-1267-08 g.chr11:5536292C>T c.1380G>A c.(1378-1380)ctG>ctA p.L460L LUSC 11 5536531 5536531 + Missense_Mutation SNP G G T TCGA-60-2722-01A-01D-1522-08 TCGA-60-2722-11A-01D-1522-08 g.chr11:5536531G>T c.1141C>A c.(1141-1143)Cca>Aca p.P381T LUSC 11 5537009 5537009 + Silent SNP G G A TCGA-66-2773-01A-01D-1267-08 TCGA-66-2773-11A-01D-1267-08 g.chr11:5537009G>A c.663C>T c.(661-663)atC>atT p.I221I LUSC 11 5537174 5537174 + Silent SNP C C A TCGA-66-2787-01A-01D-0983-08 TCGA-66-2787-11A-01D-0983-08 g.chr11:5537174C>A c.498G>T c.(496-498)gtG>gtT p.V166V LUSC 11 5537191 5537191 + Missense_Mutation SNP T T A TCGA-63-5128-01A-01D-1441-08 TCGA-63-5128-10A-01D-1441-08 g.chr11:5537191T>A c.481A>T c.(481-483)Acc>Tcc p.T161S LUSC 11 5537287 5537287 + Missense_Mutation SNP T T C TCGA-60-2715-01A-01D-1522-08 TCGA-60-2715-11A-01D-1522-08 g.chr11:5537287T>C c.385A>G c.(385-387)Aaa>Gaa p.K129E LUSC 11 5537581 5537581 + Missense_Mutation SNP T T A TCGA-34-5231-01A-21D-1817-08 TCGA-34-5231-10A-01D-1817-08 g.chr11:5537581T>A c.91A>T c.(91-93)Act>Tct p.T31S PAAD 11 5536585 5536585 + Missense_Mutation SNP T T C TCGA-2J-AABP-01A-11D-A40W-08 TCGA-2J-AABP-10A-01D-A40W-08 g.chr11:5536585T>C c.1087A>G c.(1087-1089)Att>Gtt p.I363V PAAD 11 5536814 5536814 + Missense_Mutation SNP T T G TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr11:5536814T>G c.858A>C c.(856-858)caA>caC p.Q286H PAAD 11 5537044 5537044 + Missense_Mutation SNP C C T TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr11:5537044C>T c.628G>A c.(628-630)Gaa>Aaa p.E210K PAAD 11 5537124 5537124 + Missense_Mutation SNP C C T TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr11:5537124C>T c.548G>A c.(547-549)cGg>cAg p.R183Q PRAD 11 5536527 5536527 + Missense_Mutation SNP G G A TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr11:5536527G>A c.1145C>T c.(1144-1146)gCc>gTc p.A382V PRAD 11 5537038 5537038 + Missense_Mutation SNP A A T TCGA-EJ-5519-01A-01D-1576-08 TCGA-EJ-5519-10A-01D-1577-08 g.chr11:5537038A>T c.634T>A c.(634-636)Tcc>Acc p.S212T PRAD 11 5537357 5537357 + Silent SNP G G A TCGA-KK-A8I6-01A-11D-A364-08 TCGA-KK-A8I6-11A-12D-A362-08 g.chr11:5537357G>A c.315C>T c.(313-315)ggC>ggT p.G105G READ 11 5536733 5536733 + Silent SNP T T C TCGA-CI-6619-01B-11D-1826-10 TCGA-CI-6619-10A-01D-1826-10 g.chr11:5536733T>C c.939A>G c.(937-939)ccA>ccG p.P313P READ 11 5536943 5536943 + Missense_Mutation SNP T T G TCGA-AG-3600-01A-01W-0833-10 TCGA-AG-3600-10A-01W-0833-10 g.chr11:5536943T>G c.729A>C c.(727-729)caA>caC p.Q243H READ 11 5537034 5537034 + Missense_Mutation SNP C C T TCGA-AG-3581-01A-01W-0831-10 TCGA-AG-3581-10A-01W-0831-10 g.chr11:5537034C>T c.638G>A c.(637-639)cGc>cAc p.R213H SARC 11 5537632 5537632 + Missense_Mutation SNP T T C TCGA-X6-A8C5-01A-11D-A36J-09 TCGA-X6-A8C5-10A-01D-A36M-09 g.chr11:5537632T>C c.40A>G c.(40-42)Agt>Ggt p.S14G SKCM 11 5536305 5536305 + Missense_Mutation SNP C C G TCGA-ER-A19P-06A-11D-A196-08 TCGA-ER-A19P-10A-01D-A198-08 g.chr11:5536305C>G c.1367G>C c.(1366-1368)tGg>tCg p.W456S SKCM 11 5536370 5536370 + Missense_Mutation SNP C C T TCGA-EE-A3AA-06A-11D-A196-08 TCGA-EE-A3AA-10A-01D-A198-08 g.chr11:5536370C>T c.1302G>A c.(1300-1302)atG>atA p.M434I SKCM 11 5536481 5536481 + Missense_Mutation SNP C C A TCGA-FS-A1Z3-06A-11D-A197-08 TCGA-FS-A1Z3-10A-01D-A199-08 g.chr11:5536481C>A c.1191G>T c.(1189-1191)aaG>aaT p.K397N SKCM 11 5536668 5536668 + Missense_Mutation SNP C C T TCGA-EE-A2MR-06A-11D-A196-08 TCGA-EE-A2MR-10A-01D-A198-08 g.chr11:5536668C>T c.1004G>A c.(1003-1005)aGc>aAc p.S335N SKCM 11 5536697 5536697 + Silent SNP C C T TCGA-EE-A181-06A-11D-A196-08 TCGA-EE-A181-10A-01D-A198-08 g.chr11:5536697C>T c.975G>A c.(973-975)caG>caA p.Q325Q SKCM 11 5536749 5536749 + Missense_Mutation SNP G G A TCGA-EE-A20H-06A-11D-A197-08 TCGA-EE-A20H-10A-01D-A199-08 g.chr11:5536749G>A c.923C>T c.(922-924)tCt>tTt p.S308F SKCM 11 5536967 5536967 + Silent SNP G G A TCGA-EE-A3AA-06A-11D-A196-08 TCGA-EE-A3AA-10A-01D-A198-08 g.chr11:5536967G>A c.705C>T c.(703-705)atC>atT p.I235I SKCM 11 5537037 5537037 + Missense_Mutation SNP G G A TCGA-D3-A2JF-06A-11D-A196-08 TCGA-D3-A2JF-10A-01D-A198-08 g.chr11:5537037G>A c.635C>T c.(634-636)tCc>tTc p.S212F SKCM 11 5537042 5537042 + Missense_Mutation SNP T T G TCGA-EE-A2MU-06A-21D-A196-08 TCGA-EE-A2MU-10A-01D-A198-08 g.chr11:5537042T>G c.630A>C c.(628-630)gaA>gaC p.E210D SKCM 11 5537083 5537083 + Missense_Mutation SNP C C T TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr11:5537083C>T c.589G>A c.(589-591)Gaa>Aaa p.E197K SKCM 11 5537102 5537102 + Silent SNP G G A TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr11:5537102G>A c.570C>T c.(568-570)ttC>ttT p.F190F SKCM 11 5537107 5537107 + Missense_Mutation SNP C C T TCGA-EE-A2MF-06A-11D-A21A-08 TCGA-EE-A2MF-10B-01D-A21A-08 g.chr11:5537107C>T c.565G>A c.(565-567)Gag>Aag p.E189K SKCM 11 5537108 5537108 + Missense_Mutation SNP C C T TCGA-EB-A5SG-06A-11D-A30X-08 TCGA-EB-A5SG-10A-01D-A30X-08 g.chr11:5537108C>T c.564G>A c.(562-564)atG>atA p.M188I SKCM 11 5537114 5537114 + Silent SNP G G A TCGA-DA-A1IC-06A-11D-A197-08 TCGA-DA-A1IC-10A-01D-A199-08 g.chr11:5537114G>A c.558C>T c.(556-558)tcC>tcT p.S186S SKCM 11 5537115 5537115 + Missense_Mutation SNP G G A TCGA-GF-A6C9-06A-11D-A30X-08 TCGA-GF-A6C9-10A-01D-A30X-08 g.chr11:5537115G>A c.557C>T c.(556-558)tCc>tTc p.S186F SKCM 11 5537200 5537200 + Missense_Mutation SNP T T C TCGA-EE-A2A2-06A-11D-A196-08 TCGA-EE-A2A2-10A-01D-A198-08 g.chr11:5537200T>C c.472A>G c.(472-474)Aaa>Gaa p.K158E SKCM 11 5537224 5537224 + Missense_Mutation SNP G G A TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr11:5537224G>A c.448C>T c.(448-450)Cac>Tac p.H150Y SKCM 11 5537225 5537225 + Silent SNP G G A TCGA-ER-A19N-06A-11D-A197-08 TCGA-ER-A19N-10A-01D-A199-08 g.chr11:5537225G>A c.447C>T c.(445-447)gcC>gcT p.A149A SKCM 11 5537225 5537225 + Silent SNP G G A TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr11:5537225G>A c.447C>T c.(445-447)gcC>gcT p.A149A SKCM 11 5537283 5537283 + Missense_Mutation SNP C C T TCGA-FS-A1ZW-06A-12D-A197-08 TCGA-FS-A1ZW-10A-01D-A199-08 g.chr11:5537283C>T c.389G>A c.(388-390)gGa>gAa p.G130E SKCM 11 5537318 5537318 + Silent SNP C C T TCGA-EE-A2MQ-06A-11D-A197-08 TCGA-EE-A2MQ-10A-01D-A199-08 g.chr11:5537318C>T c.354G>A c.(352-354)acG>acA p.T118T SKCM 11 5537318 5537318 + Silent SNP C C T TCGA-EE-A2MR-06A-11D-A196-08 TCGA-EE-A2MR-10A-01D-A198-08 g.chr11:5537318C>T c.354G>A c.(352-354)acG>acA p.T118T SKCM 11 5537331 5537331 + Missense_Mutation SNP C C T TCGA-EE-A3J4-06A-11D-A20D-08 TCGA-EE-A3J4-10A-01D-A20D-08 g.chr11:5537331C>T c.341G>A c.(340-342)cGg>cAg p.R114Q SKCM 11 5537337 5537337 + Missense_Mutation SNP G G A TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr11:5537337G>A c.335C>T c.(334-336)tCc>tTc p.S112F SKCM 11 5537394 5537394 + Missense_Mutation SNP C C A TCGA-D9-A1JW-06A-11D-A19A-08 TCGA-D9-A1JW-10A-01D-A19A-08 g.chr11:5537394C>A c.278G>T c.(277-279)gGc>gTc p.G93V SKCM 11 5537407 5537407 + Missense_Mutation SNP C C T TCGA-GF-A3OT-06A-23D-A23B-08 TCGA-GF-A3OT-10A-01D-A23B-08 g.chr11:5537407C>T c.265G>A c.(265-267)Ggc>Agc p.G89S SKCM 11 5537408 5537408 + Silent SNP C C T TCGA-GF-A3OT-06A-23D-A23B-08 TCGA-GF-A3OT-10A-01D-A23B-08 g.chr11:5537408C>T c.264G>A c.(262-264)agG>agA p.R88R SKCM 11 5537450 5537450 + Silent SNP G G A TCGA-DA-A3F3-06A-11D-A20D-08 TCGA-DA-A3F3-10A-01D-A20D-08 g.chr11:5537450G>A c.222C>T c.(220-222)ttC>ttT p.F74F SKCM 11 5537589 5537589 + Missense_Mutation SNP G G A TCGA-EE-A2GC-06A-11D-A197-08 TCGA-EE-A2GC-10A-01D-A199-08 g.chr11:5537589G>A c.83C>T c.(82-84)tCa>tTa p.S28L

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US 11 5537271 5537271 single base substitution C G missense_variant R134T 401G>C BOCA-FR 11 5539873 5539873 single base substitution C T upstream_gene_variant BRCA-EU 11 5531236 5531236 single base substitution G A downstream_gene_variant BRCA-EU 11 5531596 5531596 deletion of <=200bp T - downstream_gene_variant BRCA-EU 11 5531968 5531968 deletion of <=200bp A - downstream_gene_variant BRCA-EU 11 5532950 5532950 single base substitution G T downstream_gene_variant BRCA-EU 11 5533755 5533755 single base substitution C T downstream_gene_variant BRCA-EU 11 5534385 5534385 single base substitution C T downstream_gene_variant BRCA-EU 11 5534791 5534791 single base substitution C G downstream_gene_variant BRCA-EU 11 5535373 5535373 single base substitution G A downstream_gene_variant BRCA-EU 11 5535576 5535576 single base substitution A G downstream_gene_variant BRCA-EU 11 5535580 5535580 single base substitution T C downstream_gene_variant BRCA-EU 11 5535941 5535941 single base substitution C T 3_prime_UTR_variant BRCA-EU 11 5539053 5539053 single base substitution G C upstream_gene_variant BRCA-EU 11 5539546 5539546 single base substitution T A upstream_gene_variant BRCA-EU 11 5540136 5540136 single base substitution C T upstream_gene_variant BRCA-EU 11 5541486 5541486 single base substitution C T upstream_gene_variant BRCA-EU 11 5542206 5542206 single base substitution G T upstream_gene_variant BRCA-EU 11 5542409 5542409 deletion of <=200bp A - upstream_gene_variant BRCA-FR 11 5532950 5532950 single base substitution G T downstream_gene_variant BRCA-FR 11 5534791 5534791 single base substitution C G downstream_gene_variant BRCA-FR 11 5535373 5535373 single base substitution G A downstream_gene_variant BTCA-JP 11 5530631 5530631 single base substitution C T downstream_gene_variant BTCA-JP 11 5530730 5530730 single base substitution T A downstream_gene_variant BTCA-JP 11 5536309 5536309 single base substitution G C missense_variant Q455E 1363C>G CESC-US 11 5536549 5536549 single base substitution G A missense_variant R375W 1123C>T CESC-US 11 5537435 5537435 single base substitution G C synonymous_variant L79L 237C>G CLLE-ES 11 5532756 5532756 single base substitution C A downstream_gene_variant COAD-US 11 5530651 5530651 single base substitution C A downstream_gene_variant COAD-US 11 5536505 5536505 single base substitution G A synonymous_variant T389T 1167C>T COAD-US 11 5536602 5536602 single base substitution T C missense_variant K357R 1070A>G COAD-US 11 5536650 5536650 single base substitution G A missense_variant S341L 1022C>T COAD-US 11 5536870 5536870 single base substitution T A missense_variant N268Y 802A>T COAD-US 11 5537034 5537034 single base substitution C T missense_variant R213H 638G>A COCA-CN 11 5536683 5536683 single base substitution C T missense_variant R330Q 989G>A COCA-CN 11 5537016 5537016 single base substitution G T missense_variant S219Y 656C>A COCA-CN 11 5537527 5537527 single base substitution C T missense_variant D49N 145G>A COCA-CN 11 5537610 5537610 single base substitution A G missense_variant L21P 62T>C COCA-CN 11 5541100 5541100 single base substitution G T upstream_gene_variant COCA-CN 11 5541111 5541111 single base substitution A G upstream_gene_variant COCA-CN 11 5541117 5541117 single base substitution C T upstream_gene_variant ESAD-UK 11 5530631 5530631 single base substitution C T downstream_gene_variant ESAD-UK 11 5530778 5530778 single base substitution C A downstream_gene_variant ESAD-UK 11 5530933 5530933 single base substitution G A downstream_gene_variant ESAD-UK 11 5531052 5531052 single base substitution G T downstream_gene_variant ESAD-UK 11 5531342 5531342 single base substitution A C downstream_gene_variant ESAD-UK 11 5531446 5531446 single base substitution T G downstream_gene_variant ESAD-UK 11 5531560 5531560 single base substitution T G downstream_gene_variant ESAD-UK 11 5531998 5531998 single base substitution A C downstream_gene_variant ESAD-UK 11 5532533 5532533 single base substitution A C downstream_gene_variant ESAD-UK 11 5532826 5532826 single base substitution G A downstream_gene_variant ESAD-UK 11 5533071 5533071 single base substitution A C downstream_gene_variant ESAD-UK 11 5533401 5533401 single base substitution G A downstream_gene_variant ESAD-UK 11 5533404 5533404 single base substitution T G downstream_gene_variant ESAD-UK 11 5533576 5533576 single base substitution C T downstream_gene_variant ESAD-UK 11 5534190 5534190 single base substitution A C downstream_gene_variant ESAD-UK 11 5534347 5534347 single base substitution T G downstream_gene_variant ESAD-UK 11 5535170 5535170 single base substitution A G downstream_gene_variant ESAD-UK 11 5535177 5535177 single base substitution C A downstream_gene_variant ESAD-UK 11 5535362 5535362 single base substitution T G downstream_gene_variant ESAD-UK 11 5535586 5535586 single base substitution T C downstream_gene_variant ESAD-UK 11 5535749 5535749 single base substitution G A 3_prime_UTR_variant ESAD-UK 11 5536748 5536748 single base substitution A G synonymous_variant S308S 924T>C ESAD-UK 11 5536854 5536854 single base substitution T G missense_variant N273T 818A>C ESAD-UK 11 5537465 5537465 single base substitution T G missense_variant Q69H 207A>C ESAD-UK 11 5537633 5537633 single base substitution C T synonymous_variant Q13Q 39G>A ESAD-UK 11 5537966 5537966 single base substitution C T upstream_gene_variant ESAD-UK 11 5538251 5538251 single base substitution A C upstream_gene_variant ESAD-UK 11 5538251 5538251 single base substitution A G upstream_gene_variant ESAD-UK 11 5539577 5539577 deletion of <=200bp C - upstream_gene_variant ESAD-UK 11 5539730 5539730 single base substitution T G upstream_gene_variant ESAD-UK 11 5540385 5540385 single base substitution A G upstream_gene_variant ESAD-UK 11 5540836 5540836 single base substitution G T upstream_gene_variant ESAD-UK 11 5542409 5542409 insertion of <=200bp - A upstream_gene_variant ESAD-UK 11 5542584 5542584 single base substitution C A upstream_gene_variant ESCA-CN 11 5537223 5537223 single base substitution T C missense_variant H150R 449A>G ESCA-CN 11 5537661 5537661 single base substitution G C missense_variant A4G 11C>G KIRC-US 11 5537653 5537653 single base substitution G A stop_gained R7* 19C>T LAML-KR 11 5536309 5536309 single base substitution G C missense_variant Q455E 1363C>G LGG-US 11 5530632 5530632 single base substitution G A downstream_gene_variant LICA-CN 11 5536526 5536526 single base substitution G C synonymous_variant A382A 1146C>G LICA-CN 11 5537189 5537189 single base substitution G T synonymous_variant T161T 483C>A LICA-FR 11 5535948 5535948 single base substitution T C 3_prime_UTR_variant LICA-FR 11 5538883 5538883 single base substitution G C upstream_gene_variant LICA-FR 11 5539234 5539234 single base substitution G A upstream_gene_variant LIHC-US 11 5537570 5537570 single base substitution T A synonymous_variant I34I 102A>T LIRI-JP 11 5531141 5531141 single base substitution C T downstream_gene_variant LIRI-JP 11 5531292 5531292 single base substitution T A downstream_gene_variant LIRI-JP 11 5532060 5532060 single base substitution G C downstream_gene_variant LIRI-JP 11 5534319 5534319 single base substitution T A downstream_gene_variant LIRI-JP 11 5534755 5534755 single base substitution T C downstream_gene_variant LIRI-JP 11 5535122 5535122 single base substitution C T downstream_gene_variant LIRI-JP 11 5535470 5535470 single base substitution T C downstream_gene_variant LIRI-JP 11 5535505 5535505 single base substitution T C downstream_gene_variant LIRI-JP 11 5536355 5536355 single base substitution C T synonymous_variant L439L 1317G>A LIRI-JP 11 5536449 5536449 single base substitution T C missense_variant Q408R 1223A>G LIRI-JP 11 5538741 5538741 single base substitution T C upstream_gene_variant LIRI-JP 11 5538974 5538974 single base substitution C G upstream_gene_variant LIRI-JP 11 5542514 5542514 single base substitution C T upstream_gene_variant LUSC-KR 11 5533354 5533354 single base substitution C A downstream_gene_variant LUSC-KR 11 5533858 5533858 single base substitution G T downstream_gene_variant LUSC-KR 11 5536415 5536415 single base substitution C T synonymous_variant E419E 1257G>A LUSC-KR 11 5536852 5536852 single base substitution A G missense_variant Y274H 820T>C LUSC-KR 11 5537045 5537045 single base substitution T G synonymous_variant P209P 627A>C LUSC-KR 11 5537161 5537161 single base substitution A G missense_variant C171R 511T>C LUSC-KR 11 5540178 5540178 single base substitution C G upstream_gene_variant LUSC-KR 11 5541525 5541525 single base substitution C G upstream_gene_variant LUSC-US 11 5536292 5536292 single base substitution C T synonymous_variant L460L 1380G>A LUSC-US 11 5536531 5536531 single base substitution G T missense_variant P381T 1141C>A LUSC-US 11 5537009 5537009 single base substitution G A synonymous_variant I221I 663C>T LUSC-US 11 5537174 5537174 single base substitution C A synonymous_variant V166V 498G>T LUSC-US 11 5537191 5537191 single base substitution T A missense_variant T161S 481A>T LUSC-US 11 5537287 5537287 single base substitution T C missense_variant K129E 385A>G LUSC-US 11 5537581 5537581 single base substitution T A missense_variant T31S 91A>T MALY-DE 11 5541139 5541139 single base substitution T G upstream_gene_variant MELA-AU 11 5530648 5530648 single base substitution C T downstream_gene_variant MELA-AU 11 5530734 5530734 single base substitution G A downstream_gene_variant MELA-AU 11 5530843 5530843 single base substitution G A downstream_gene_variant MELA-AU 11 5530858 5530858 single base substitution C T downstream_gene_variant MELA-AU 11 5530888 5530888 single base substitution G A downstream_gene_variant MELA-AU 11 5530894 5530894 single base substitution G A downstream_gene_variant MELA-AU 11 5530921 5530921 single base substitution G A downstream_gene_variant MELA-AU 11 5530941 5530941 single base substitution G A downstream_gene_variant MELA-AU 11 5531011 5531011 single base substitution G A downstream_gene_variant MELA-AU 11 5531078 5531078 single base substitution G A downstream_gene_variant MELA-AU 11 5531085 5531085 single base substitution C T downstream_gene_variant MELA-AU 11 5531149 5531149 single base substitution C T downstream_gene_variant MELA-AU 11 5531212 5531212 single base substitution C T downstream_gene_variant MELA-AU 11 5531214 5531214 single base substitution C T downstream_gene_variant MELA-AU 11 5531331 5531331 single base substitution C T downstream_gene_variant MELA-AU 11 5531437 5531437 single base substitution T A downstream_gene_variant MELA-AU 11 5531448 5531448 single base substitution C T downstream_gene_variant MELA-AU 11 5531514 5531514 single base substitution G A downstream_gene_variant MELA-AU 11 5531545 5531545 single base substitution C T downstream_gene_variant MELA-AU 11 5531555 5531555 single base substitution T C downstream_gene_variant MELA-AU 11 5531558 5531558 single base substitution G A downstream_gene_variant MELA-AU 11 5531576 5531576 single base substitution G A downstream_gene_variant MELA-AU 11 5531598 5531598 single base substitution T C downstream_gene_variant MELA-AU 11 5531628 5531628 single base substitution C T downstream_gene_variant MELA-AU 11 5531750 5531750 single base substitution G A downstream_gene_variant MELA-AU 11 5531779 5531779 single base substitution A G downstream_gene_variant MELA-AU 11 5531782 5531782 single base substitution C T downstream_gene_variant MELA-AU 11 5531974 5531974 single base substitution A G downstream_gene_variant MELA-AU 11 5531977 5531977 single base substitution G A downstream_gene_variant MELA-AU 11 5531995 5531995 single base substitution C T downstream_gene_variant MELA-AU 11 5532000 5532000 single base substitution G A downstream_gene_variant MELA-AU 11 5532006 5532006 single base substitution G T downstream_gene_variant MELA-AU 11 5532012 5532012 single base substitution C T downstream_gene_variant MELA-AU 11 5532104 5532104 single base substitution G A downstream_gene_variant MELA-AU 11 5532164 5532164 single base substitution G A downstream_gene_variant MELA-AU 11 5532283 5532283 single base substitution C T downstream_gene_variant MELA-AU 11 5532327 5532327 single base substitution C T downstream_gene_variant MELA-AU 11 5532360 5532360 single base substitution G A downstream_gene_variant MELA-AU 11 5532565 5532565 single base substitution G A downstream_gene_variant MELA-AU 11 5532596 5532596 single base substitution G A downstream_gene_variant MELA-AU 11 5532717 5532717 single base substitution G A downstream_gene_variant MELA-AU 11 5532850 5532850 single base substitution G A downstream_gene_variant MELA-AU 11 5532862 5532862 single base substitution G A downstream_gene_variant MELA-AU 11 5532903 5532903 single base substitution G A downstream_gene_variant MELA-AU 11 5532995 5532995 single base substitution G A downstream_gene_variant MELA-AU 11 5533004 5533004 single base substitution G A downstream_gene_variant MELA-AU 11 5533017 5533017 single base substitution G A downstream_gene_variant MELA-AU 11 5533024 5533024 single base substitution C T downstream_gene_variant MELA-AU 11 5533237 5533237 single base substitution G A downstream_gene_variant MELA-AU 11 5533238 5533238 single base substitution A C downstream_gene_variant MELA-AU 11 5533270 5533270 single base substitution C T downstream_gene_variant MELA-AU 11 5533276 5533276 single base substitution G A downstream_gene_variant MELA-AU 11 5533283 5533283 single base substitution C T downstream_gene_variant MELA-AU 11 5533317 5533317 single base substitution G A downstream_gene_variant MELA-AU 11 5533581 5533581 single base substitution G A downstream_gene_variant MELA-AU 11 5533582 5533582 single base substitution G A downstream_gene_variant MELA-AU 11 5533618 5533618 single base substitution C T downstream_gene_variant MELA-AU 11 5533671 5533671 single base substitution G A downstream_gene_variant MELA-AU 11 5533771 5533771 single base substitution T C downstream_gene_variant MELA-AU 11 5533832 5533832 single base substitution G A downstream_gene_variant MELA-AU 11 5534102 5534102 single base substitution C T downstream_gene_variant MELA-AU 11 5534138 5534138 single base substitution C T downstream_gene_variant MELA-AU 11 5534154 5534154 single base substitution A G downstream_gene_variant MELA-AU 11 5534193 5534193 single base substitution G A downstream_gene_variant MELA-AU 11 5534216 5534216 single base substitution C T downstream_gene_variant MELA-AU 11 5534282 5534283 multiple base substitution (>=2bp and <=200bp) TC GT downstream_gene_variant MELA-AU 11 5534395 5534395 single base substitution C T downstream_gene_variant MELA-AU 11 5534414 5534414 single base substitution C T downstream_gene_variant MELA-AU 11 5534796 5534796 single base substitution C T downstream_gene_variant MELA-AU 11 5534860 5534860 single base substitution G A downstream_gene_variant MELA-AU 11 5534914 5534914 single base substitution G A downstream_gene_variant MELA-AU 11 5534956 5534956 single base substitution G A downstream_gene_variant MELA-AU 11 5535258 5535258 single base substitution C T downstream_gene_variant MELA-AU 11 5535624 5535624 single base substitution C T 3_prime_UTR_variant MELA-AU 11 5535992 5535992 single base substitution C T 3_prime_UTR_variant MELA-AU 11 5536102 5536102 single base substitution G A 3_prime_UTR_variant MELA-AU 11 5536113 5536113 single base substitution G A 3_prime_UTR_variant MELA-AU 11 5536124 5536124 single base substitution G A 3_prime_UTR_variant MELA-AU 11 5536131 5536131 single base substitution A G 3_prime_UTR_variant MELA-AU 11 5536175 5536175 single base substitution G A 3_prime_UTR_variant MELA-AU 11 5536283 5536283 single base substitution G A synonymous_variant F463F 1389C>T MELA-AU 11 5536370 5536370 single base substitution C T missense_variant M434I 1302G>A MELA-AU 11 5536597 5536597 single base substitution T G missense_variant N359H 1075A>C MELA-AU 11 5536931 5536931 single base substitution G A synonymous_variant N247N 741C>T MELA-AU 11 5536967 5536967 single base substitution G A synonymous_variant I235I 705C>T MELA-AU 11 5537037 5537037 single base substitution G A missense_variant S212F 635C>T MELA-AU 11 5537090 5537090 single base substitution G A synonymous_variant F194F 582C>T MELA-AU 11 5537107 5537107 single base substitution C T missense_variant E189K 565G>A MELA-AU 11 5537155 5537155 single base substitution C T missense_variant A173T 517G>A MELA-AU 11 5537224 5537224 single base substitution G A missense_variant H150Y 448C>T MELA-AU 11 5537284 5537284 single base substitution C T missense_variant G130R 388G>A MELA-AU 11 5537333 5537333 single base substitution G A synonymous_variant F113F 339C>T MELA-AU 11 5537336 5537336 single base substitution G A synonymous_variant S112S 336C>T MELA-AU 11 5537337 5537337 single base substitution G A missense_variant S112F 335C>T MELA-AU 11 5537347 5537347 single base substitution G A synonymous_variant L109L 325C>T MELA-AU 11 5537367 5537367 single base substitution G A missense_variant S102F 305C>T MELA-AU 11 5537398 5537398 single base substitution C T missense_variant D92N 274G>A MELA-AU 11 5537431 5537431 single base substitution C T missense_variant D81N 241G>A MELA-AU 11 5537450 5537450 single base substitution G A synonymous_variant F74F 222C>T MELA-AU 11 5537482 5537482 single base substitution G A stop_gained Q64* 190C>T MELA-AU 11 5537483 5537483 single base substitution G A synonymous_variant F63F 189C>T MELA-AU 11 5537520 5537520 single base substitution G A missense_variant S51L 152C>T MELA-AU 11 5537722 5537722 single base substitution G A 5_prime_UTR_variant MELA-AU 11 5537784 5537784 single base substitution G A 5_prime_UTR_premature_start_codon_gain_variant MELA-AU 11 5537938 5537938 single base substitution G A upstream_gene_variant MELA-AU 11 5537943 5537944 multiple base substitution (>=2bp and <=200bp) CT TA upstream_gene_variant MELA-AU 11 5537949 5537949 single base substitution C T upstream_gene_variant MELA-AU 11 5537972 5537972 single base substitution C T upstream_gene_variant MELA-AU 11 5538030 5538030 single base substitution C T upstream_gene_variant MELA-AU 11 5538053 5538053 single base substitution G A upstream_gene_variant MELA-AU 11 5538117 5538118 multiple base substitution (>=2bp and <=200bp) GG AA upstream_gene_variant MELA-AU 11 5538118 5538118 single base substitution G A upstream_gene_variant MELA-AU 11 5538132 5538132 single base substitution G A upstream_gene_variant MELA-AU 11 5538170 5538170 single base substitution C T upstream_gene_variant MELA-AU 11 5538199 5538199 single base substitution C T upstream_gene_variant MELA-AU 11 5538199 5538200 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 11 5538222 5538222 single base substitution C T upstream_gene_variant MELA-AU 11 5538253 5538253 single base substitution T C upstream_gene_variant MELA-AU 11 5538307 5538307 single base substitution C T upstream_gene_variant MELA-AU 11 5538313 5538313 single base substitution G A upstream_gene_variant MELA-AU 11 5538345 5538345 single base substitution G A upstream_gene_variant MELA-AU 11 5538356 5538356 single base substitution C T upstream_gene_variant MELA-AU 11 5538364 5538364 single base substitution G A upstream_gene_variant MELA-AU 11 5538434 5538434 single base substitution G A upstream_gene_variant MELA-AU 11 5538563 5538563 single base substitution G A upstream_gene_variant MELA-AU 11 5538576 5538576 single base substitution G A upstream_gene_variant MELA-AU 11 5538837 5538837 single base substitution G A upstream_gene_variant MELA-AU 11 5538911 5538911 single base substitution G A upstream_gene_variant MELA-AU 11 5538958 5538958 single base substitution C T upstream_gene_variant MELA-AU 11 5539090 5539090 single base substitution C T upstream_gene_variant MELA-AU 11 5539174 5539174 single base substitution C T upstream_gene_variant MELA-AU 11 5539188 5539188 single base substitution G A upstream_gene_variant MELA-AU 11 5539217 5539217 single base substitution C T upstream_gene_variant MELA-AU 11 5539243 5539243 single base substitution G A upstream_gene_variant MELA-AU 11 5539253 5539253 single base substitution G C upstream_gene_variant MELA-AU 11 5539264 5539264 single base substitution G A upstream_gene_variant MELA-AU 11 5539395 5539395 single base substitution G A upstream_gene_variant MELA-AU 11 5539452 5539452 single base substitution T C upstream_gene_variant MELA-AU 11 5539463 5539463 single base substitution C T upstream_gene_variant MELA-AU 11 5539473 5539473 single base substitution C T upstream_gene_variant MELA-AU 11 5539562 5539562 single base substitution C A upstream_gene_variant MELA-AU 11 5539601 5539601 single base substitution G A upstream_gene_variant MELA-AU 11 5539612 5539612 single base substitution G A upstream_gene_variant MELA-AU 11 5539688 5539688 single base substitution T G upstream_gene_variant MELA-AU 11 5539845 5539845 single base substitution C T upstream_gene_variant MELA-AU 11 5539901 5539901 single base substitution A G upstream_gene_variant MELA-AU 11 5539984 5539984 single base substitution G A upstream_gene_variant MELA-AU 11 5540072 5540072 single base substitution C T upstream_gene_variant MELA-AU 11 5540127 5540127 single base substitution C T upstream_gene_variant MELA-AU 11 5540231 5540231 single base substitution C T upstream_gene_variant MELA-AU 11 5540856 5540856 single base substitution C T upstream_gene_variant MELA-AU 11 5540958 5540958 single base substitution G A upstream_gene_variant MELA-AU 11 5541384 5541384 single base substitution G A upstream_gene_variant MELA-AU 11 5541588 5541588 single base substitution G A upstream_gene_variant MELA-AU 11 5541699 5541699 single base substitution T C upstream_gene_variant MELA-AU 11 5541765 5541765 single base substitution G A upstream_gene_variant MELA-AU 11 5541856 5541856 single base substitution G A upstream_gene_variant MELA-AU 11 5542115 5542115 single base substitution C T upstream_gene_variant MELA-AU 11 5542146 5542146 single base substitution G A upstream_gene_variant MELA-AU 11 5542148 5542148 single base substitution G A upstream_gene_variant MELA-AU 11 5542491 5542491 single base substitution G A upstream_gene_variant MELA-AU 11 5542533 5542533 single base substitution G A upstream_gene_variant MELA-AU 11 5542640 5542640 single base substitution G A upstream_gene_variant MELA-AU 11 5542846 5542846 single base substitution C T upstream_gene_variant ORCA-IN 11 5541117 5541117 single base substitution C T upstream_gene_variant OV-AU 11 5531619 5531619 single base substitution T C downstream_gene_variant OV-AU 11 5531788 5531788 single base substitution T C downstream_gene_variant OV-AU 11 5532752 5532752 single base substitution G T downstream_gene_variant OV-AU 11 5534744 5534744 single base substitution G A downstream_gene_variant OV-AU 11 5535266 5535266 single base substitution A T downstream_gene_variant PACA-AU 11 5531672 5531672 single base substitution G A downstream_gene_variant PACA-AU 11 5535511 5535511 single base substitution A T downstream_gene_variant PACA-AU 11 5536655 5536655 single base substitution G T missense_variant F339L 1017C>A PACA-AU 11 5538092 5538092 single base substitution A G upstream_gene_variant PACA-AU 11 5538373 5538373 single base substitution T A upstream_gene_variant PACA-AU 11 5538615 5538615 single base substitution C A upstream_gene_variant PACA-AU 11 5540142 5540152 deletion of <=200bp AGCATAGGAAA - upstream_gene_variant PACA-AU 11 5540829 5540829 deletion of <=200bp A - upstream_gene_variant PACA-AU 11 5541440 5541440 single base substitution A G upstream_gene_variant PACA-AU 11 5542386 5542386 single base substitution C A upstream_gene_variant PACA-AU 11 5542387 5542387 single base substitution A C upstream_gene_variant PACA-CA 11 5530931 5530931 single base substitution G A downstream_gene_variant PACA-CA 11 5531028 5531028 single base substitution G C downstream_gene_variant PACA-CA 11 5531235 5531235 single base substitution C T downstream_gene_variant PACA-CA 11 5533478 5533480 deletion of <=200bp ATT - downstream_gene_variant PACA-CA 11 5534722 5534722 single base substitution A G downstream_gene_variant PACA-CA 11 5535186 5535186 deletion of <=200bp T - downstream_gene_variant PACA-CA 11 5535625 5535625 single base substitution G A 3_prime_UTR_variant PACA-CA 11 5535811 5535811 single base substitution A G 3_prime_UTR_variant PAEN-AU 11 5530630 5530630 single base substitution G T downstream_gene_variant PAEN-AU 11 5541853 5541853 single base substitution C T upstream_gene_variant PRAD-UK 11 5532910 5532910 single base substitution T C downstream_gene_variant PRAD-UK 11 5536548 5536548 single base substitution C T missense_variant R375Q 1124G>A PRAD-UK 11 5541082 5541082 single base substitution G A upstream_gene_variant PRAD-US 11 5537038 5537038 single base substitution A T missense_variant S212T 634T>A READ-US 11 5536990 5536990 single base substitution G T missense_variant L228M 682C>A READ-US 11 5537465 5537465 single base substitution T G missense_variant Q69H 207A>C READ-US 11 5537635 5537635 single base substitution G A stop_gained Q13* 37C>T RECA-EU 11 5539167 5539167 single base substitution G T upstream_gene_variant SKCA-BR 11 5530635 5530635 single base substitution G A downstream_gene_variant SKCA-BR 11 5531077 5531077 single base substitution G A downstream_gene_variant SKCA-BR 11 5531217 5531217 single base substitution C T downstream_gene_variant SKCA-BR 11 5531286 5531286 single base substitution G A downstream_gene_variant SKCA-BR 11 5531523 5531523 single base substitution A C downstream_gene_variant SKCA-BR 11 5531577 5531577 single base substitution G A downstream_gene_variant SKCA-BR 11 5534719 5534719 single base substitution A C downstream_gene_variant SKCA-BR 11 5534809 5534809 single base substitution G A downstream_gene_variant SKCA-BR 11 5535003 5535003 single base substitution G A downstream_gene_variant SKCA-BR 11 5535750 5535750 single base substitution G A 3_prime_UTR_variant SKCA-BR 11 5536852 5536852 single base substitution A G missense_variant Y274H 820T>C SKCA-BR 11 5536931 5536931 single base substitution G A synonymous_variant N247N 741C>T SKCA-BR 11 5537504 5537504 single base substitution C T synonymous_variant K56K 168G>A SKCA-BR 11 5538318 5538318 single base substitution G A upstream_gene_variant SKCA-BR 11 5538422 5538422 single base substitution C T upstream_gene_variant SKCA-BR 11 5540003 5540003 single base substitution T G upstream_gene_variant SKCA-BR 11 5541117 5541117 single base substitution C T upstream_gene_variant SKCA-BR 11 5542733 5542733 insertion of <=200bp - CA upstream_gene_variant SKCM-US 11 5530692 5530692 single base substitution C T downstream_gene_variant SKCM-US 11 5536370 5536370 single base substitution C T missense_variant M434I 1302G>A SKCM-US 11 5536481 5536481 single base substitution C A missense_variant K397N 1191G>T SKCM-US 11 5536668 5536668 single base substitution C T missense_variant S335N 1004G>A SKCM-US 11 5536697 5536697 single base substitution C T synonymous_variant Q325Q 975G>A SKCM-US 11 5536749 5536749 single base substitution G A missense_variant S308F 923C>T SKCM-US 11 5536874 5536874 single base substitution C T synonymous_variant G266G 798G>A SKCM-US 11 5537037 5537037 single base substitution G A missense_variant S212F 635C>T SKCM-US 11 5537042 5537042 single base substitution T G missense_variant E210D 630A>C SKCM-US 11 5537083 5537083 single base substitution C T missense_variant E197K 589G>A SKCM-US 11 5537102 5537102 single base substitution G A synonymous_variant F190F 570C>T SKCM-US 11 5537107 5537107 single base substitution C T missense_variant E189K 565G>A SKCM-US 11 5537108 5537108 single base substitution C T missense_variant M188I 564G>A SKCM-US 11 5537114 5537114 single base substitution G A synonymous_variant S186S 558C>T SKCM-US 11 5537115 5537115 single base substitution G A missense_variant S186F 557C>T SKCM-US 11 5537200 5537200 single base substitution T C missense_variant K158E 472A>G SKCM-US 11 5537225 5537225 single base substitution G A synonymous_variant A149A 447C>T SKCM-US 11 5537283 5537283 single base substitution C T missense_variant G130E 389G>A SKCM-US 11 5537318 5537318 single base substitution C T synonymous_variant T118T 354G>A SKCM-US 11 5537331 5537331 single base substitution C T missense_variant R114Q 341G>A SKCM-US 11 5537337 5537337 single base substitution G A missense_variant S112F 335C>T SKCM-US 11 5537394 5537394 single base substitution C A missense_variant G93V 278G>T SKCM-US 11 5537395 5537395 single base substitution C T missense_variant G93S 277G>A SKCM-US 11 5537450 5537450 single base substitution G A synonymous_variant F74F 222C>T SKCM-US 11 5537589 5537589 single base substitution G A missense_variant S28L 83C>T STAD-US 11 5536427 5536451 deletion of <=200bp CTGGAGATCACCCTTTAATGTCTGT - frameshift_variant RQTLKGDLQ407 STAD-US 11 5536466 5536466 single base substitution A T synonymous_variant S402S 1206T>A STAD-US 11 5536502 5536502 single base substitution C T synonymous_variant Q390Q 1170G>A STAD-US 11 5536964 5536964 single base substitution T C synonymous_variant Q236Q 708A>G STAD-US 11 5536964 5536964 single base substitution T G missense_variant Q236H 708A>C STAD-US 11 5536993 5536993 single base substitution C A stop_gained E227* 679G>T STAD-US 11 5537086 5537086 single base substitution A G missense_variant S196P 586T>C STAD-US 11 5537100 5537100 single base substitution A G missense_variant M191T 572T>C STAD-US 11 5537169 5537169 single base substitution T C missense_variant H168R 503A>G STAD-US 11 5537480 5537480 single base substitution T C synonymous_variant Q64Q 192A>G STAD-US 11 5537570 5537570 single base substitution T C missense_variant I34M 102A>G STAD-US 11 5537612 5537612 single base substitution C A synonymous_variant L20L 60G>T UCEC-US 11 5530637 5530637 single base substitution G T downstream_gene_variant UCEC-US 11 5536485 5536485 single base substitution T C missense_variant Y396C 1187A>G UCEC-US 11 5536502 5536502 single base substitution C A missense_variant Q390H 1170G>T UCEC-US 11 5536513 5536513 single base substitution C T missense_variant E387K 1159G>A UCEC-US 11 5536528 5536528 single base substitution C T missense_variant A382T 1144G>A UCEC-US 11 5536566 5536566 single base substitution C A missense_variant S369I 1106G>T UCEC-US 11 5536690 5536690 single base substitution C T missense_variant A328T 982G>A UCEC-US 11 5536751 5536751 single base substitution C A missense_variant Q307H 921G>T UCEC-US 11 5536961 5536961 single base substitution C A missense_variant E237D 711G>T UCEC-US 11 5537017 5537017 single base substitution A C missense_variant S219A 655T>G UCEC-US 11 5537034 5537034 single base substitution C T missense_variant R213H 638G>A

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand SNUH_G73_S1 COSM3998461 c.1257G>A p.E419E Substitution - coding silent 11:5515185-5515185 - C086 COSM3448903 c.635C>T p.S212F Substitution - Missense 11:5515807-5515807 - HOP-92 COSM1675774 c.7C>A p.H3N Substitution - Missense 11:5516435-5516435 - YUMUL COSM4488714 c.336C>T p.S112S Substitution - coding silent 11:5516106-5516106 - TCGA-34-5231-01 COSM688939 c.91A>T p.T31S Substitution - Missense 11:5516351-5516351 - C086 COSM5541295 c.456G>A p.V152V Substitution - coding silent 11:5515986-5515986 - C91 COSM4444347 c.1186T>A p.Y396N Substitution - Missense 11:5515256-5515256 - TCGA-B5-A11E-01 COSM928047 c.711G>T p.E237D Substitution - Missense 11:5515731-5515731 - Pat_08_B COSM5838755 c.1019C>T p.S340F Substitution - Missense 11:5515423-5515423 - CHEWS001 COSM4574442 c.1234G>A p.G412S Substitution - Missense 11:5515208-5515208 - 1T COSM107671 c.1082C>T p.A361V Substitution - Missense 11:5515360-5515360 - 2218461 COSM4194440 c.1192G>A p.D398N Substitution - Missense 11:5515250-5515250 - STC246 COSM1732597 c.669G>T p.L223F Substitution - Missense 11:5515773-5515773 - TCGA-AA-3715-01 COSM270495 c.603G>A p.T201T Substitution - coding silent 11:5515839-5515839 - S02244 COSM5678077 c.872G>C p.G291A Substitution - Missense 11:5515570-5515570 - TCGA-AX-A0J0-01 COSM287867 c.638G>A p.R213H Substitution - Missense 11:5515804-5515804 - TCGA-CA-6717-01 COSM1354409 c.1070A>G p.K357R Substitution - Missense 11:5515372-5515372 - HCA7 COSM4629759 c.557C>T p.S186F Substitution - Missense 11:5515885-5515885 - TCGA-63-5128-01 COSM688941 c.481A>T p.T161S Substitution - Missense 11:5515961-5515961 - T3090 COSM4738796 c.697G>T p.A233S Substitution - Missense 11:5515745-5515745 - C086 COSM5541293 c.493G>A p.E165K Substitution - Missense 11:5515949-5515949 - TCGA-66-2787-01 COSM688943 c.498G>T p.V166V Substitution - coding silent 11:5515944-5515944 - CPCG0184-P3 COSM147120 c.824C>T p.A275V Substitution - Missense 11:5515618-5515618 - YUSCA COSM5372708 c.862C>T p.P288S Substitution - Missense 11:5515580-5515580 - C086 COSM5541294 c.377G>A p.R126K Substitution - Missense 11:5516065-5516065 - CSCC-27-T COSM4553673 c.598G>A p.D200N Substitution - Missense 11:5515844-5515844 - CPCG0183-P2 COSM147120 c.824C>T p.A275V Substitution - Missense 11:5515618-5515618 - CN-AML-08-T COSM5425665 c.1363C>G p.Q455E Substitution - Missense 11:5515079-5515079 - TCGA-EE-A20H-06 COSM3448901 c.923C>T p.S308F Substitution - Missense 11:5515519-5515519 - TCGA-D9-A1JW-06 COSM3448923 c.278G>T p.G93V Substitution - Missense 11:5516164-5516164 - EGC15 COSM5050876 c.1404G>A p.Q468Q Substitution - coding silent 11:5515038-5515038 - HCT-15 COSM1675773 c.686C>A p.A229D Substitution - Missense 11:5515756-5515756 - C91 COSM4444348 c.1021T>G p.S341A Substitution - Missense 11:5515421-5515421 - C135 COSM4617141 c.526C>T p.L176L Substitution - coding silent 11:5515916-5515916 - TCGA-CG-4474-01 COSM4033647 c.60G>T p.L20L Substitution - coding silent 11:5516382-5516382 - TCGA-BR-4363-01 COSM4033630 c.1206T>A p.S402S Substitution - coding silent 11:5515236-5515236 - SS6003149 COSM3415949 c.207A>C p.Q69H Substitution - Missense 11:5516235-5516235 - TCGA-60-2722-01 COSM688954 c.1141C>A p.P381T Substitution - Missense 11:5515301-5515301 - TCGA-JW-A5VL-01 COSM4846636 c.237C>G p.L79L Substitution - coding silent 11:5516205-5516205 - 2334195 COSM324160 c.1105A>T p.S369C Substitution - Missense 11:5515337-5515337 - 2171676 COSM4423423 c.415A>T p.T139S Substitution - Missense 11:5516027-5516027 - TCGA-FR-A3R1-01 COSM3448924 c.277G>A p.G93S Substitution - Missense 11:5516165-5516165 - ESO-0079 COSM1269650 c.890T>G p.L297R Substitution - Missense 11:5515552-5515552 - TCGA-AP-A051-01 COSM928041 c.1170G>T p.Q390H Substitution - Missense 11:5515272-5515272 - pfg272T COSM4749180 c.1409C>A p.S470Y Substitution - Missense 11:5515033-5515033 - RK088_C01 COSM3700089 c.1223A>G p.Q408R Substitution - Missense 11:5515219-5515219 - ATL020 COSM5704041 c.302A>G p.K101R Substitution - Missense 11:5516140-5516140 - MO_1013 COSM5117689 c.628G>A p.E210K Substitution - Missense 11:5515814-5515814 - TCGA-BR-8487-01 COSM4033636 c.572T>C p.M191T Substitution - Missense 11:5515870-5515870 - TCGA-EE-A181-06 COSM3448900 c.975G>A p.Q325Q Substitution - coding silent 11:5515467-5515467 - 10-276 COSM3736724 c.53C>T p.S18L Substitution - Missense 11:5516389-5516389 - JVM-2 COSM1741014 c.951delG p.E318fs*45 Deletion - Frameshift 11:5515491-5515491 - BD87T COSM5425665 c.1363C>G p.Q455E Substitution - Missense 11:5515079-5515079 - ATL065 COSM5704042 c.227G>A p.G76D Substitution - Missense 11:5516215-5516215 - TCGA-B5-A0JY-01 COSM928043 c.1144G>A p.A382T Substitution - Missense 11:5515298-5515298 - LS174T COSM4194447 c.665T>C p.L222P Substitution - Missense 11:5515777-5515777 - PT40 COSM5923946 c.938C>T p.P313L Substitution - Missense 11:5515504-5515504 - CPCG0184-P2 COSM147120 c.824C>T p.A275V Substitution - Missense 11:5515618-5515618 - TCGA-EE-A3J4-06 COSM3869383 c.341G>A p.R114Q Substitution - Missense 11:5516101-5516101 - LUAD-F00162 COSM366055 c.94C>A p.R32R Substitution - coding silent 11:5516348-5516348 - TCGA-B7-5816-01 COSM4033646 c.102A>G p.I34M Substitution - Missense 11:5516340-5516340 - TCGA-FD-A3SO-01 COSM324161 c.401G>C p.R134T Substitution - Missense 11:5516041-5516041 - SNUH_G10_S1 COSM3998462 c.627A>C p.P209P Substitution - coding silent 11:5515815-5515815 - Pat_08_A COSM5838755 c.1019C>T p.S340F Substitution - Missense 11:5515423-5515423 - Pat_41_A COSM3869383 c.341G>A p.R114Q Substitution - Missense 11:5516101-5516101 - TCGA-EE-A2MU-06 COSM1231603 c.630A>C p.E210D Substitution - Missense 11:5515812-5515812 - PDA_008 COSM3927699 c.820T>C p.Y274H Substitution - Missense 11:5515622-5515622 - TCGA-60-2715-01 COSM688940 c.385A>G p.K129E Substitution - Missense 11:5516057-5516057 - PT46 COSM3448921 c.389G>A p.G130E Substitution - Missense 11:5516053-5516053 - Pat_28_B COSM5582980 c.926C>T p.S309L Substitution - Missense 11:5515516-5515516 - ESCC_BICR_054T COSM5444179 c.11C>G p.A4G Substitution - Missense 11:5516431-5516431 - CSCC-37-T COSM4488714 c.336C>T p.S112S Substitution - coding silent 11:5516106-5516106 - HN_63021 COSM130046 c.1201G>T p.V401F Substitution - Missense 11:5515241-5515241 - YUROG COSM1354413 c.872G>A p.G291E Substitution - Missense 11:5515570-5515570 - TCGA-AP-A051-01 COSM928046 c.921G>T p.Q307H Substitution - Missense 11:5515521-5515521 - YULAD COSM4501184 c.582C>T p.F194F Substitution - coding silent 11:5515860-5515860 - 256528 COSM3726825 c.1248_1249insT p.S417fs*3 Insertion - Frameshift 11:5515193-5515194 - TCGA-CK-4948-01 COSM1354410 c.1022C>T p.S341L Substitution - Missense 11:5515420-5515420 - TCGA-CK-5916-01 COSM287867 c.638G>A p.R213H Substitution - Missense 11:5515804-5515804 - VCB-PH-02T COSM4770629 c.235C>G p.L79V Substitution - Missense 11:5516207-5516207 - Pat_14_A COSM5838756 c.580T>C p.F194L Substitution - Missense 11:5515862-5515862 - SNUH_G73_S1 COSM3998462 c.627A>C p.P209P Substitution - coding silent 11:5515815-5515815 - ESO-720 COSM1269652 c.1011T>C p.G337G Substitution - coding silent 11:5515431-5515431 - TCGA-LP-A4AW-01 COSM4194442 c.1123C>T p.R375W Substitution - Missense 11:5515319-5515319 - RK189_C01 COSM1628047 c.1317G>A p.L439L Substitution - coding silent 11:5515125-5515125 - HCT-15 COSM1675771 c.1241T>G p.L414R Substitution - Missense 11:5515201-5515201 - CN-AML-NR-08-Dx COSM5425665 c.1363C>G p.Q455E Substitution - Missense 11:5515079-5515079 - 1N24-VS-1T24 COSM4194475 c.512G>A p.C171Y Substitution - Missense 11:5515930-5515930 - TCGA-AP-A059-01 COSM928044 c.1106G>T p.S369I Substitution - Missense 11:5515336-5515336 - TCGA-66-2773-01 COSM688955 c.1380G>A p.L460L Substitution - coding silent 11:5515062-5515062 - CPCG0184-P3 COSM3927699 c.820T>C p.Y274H Substitution - Missense 11:5515622-5515622 - DLD1 COSM1675771 c.1241T>G p.L414R Substitution - Missense 11:5515201-5515201 - HCC086T COSM5813163 c.483C>A p.T161T Substitution - coding silent 11:5515959-5515959 - TCGA-FS-A1ZW-06 COSM3448921 c.389G>A p.G130E Substitution - Missense 11:5516053-5516053 - FM474T COSM673806 c.833A>G p.N278S Substitution - Missense 11:5515609-5515609 - TCGA-CD-5801-01 COSM4033634 c.679G>T p.E227* Substitution - Nonsense 11:5515763-5515763 - S01022 COSM5665646 c.1356G>C p.L452L Substitution - coding silent 11:5515086-5515086 - S02242 COSM5677062 c.116G>T p.G39V Substitution - Missense 11:5516326-5516326 - YURUS COSM1703469 c.439G>A p.E147K Substitution - Missense 11:5516003-5516003 - 6115118 COSM5570726 c.437T>C p.V146A Substitution - Missense 11:5516005-5516005 - TCGA-BR-8289-01 COSM4033633 c.708A>C p.Q236H Substitution - Missense 11:5515734-5515734 - HCT15 COSM1675771 c.1241T>G p.L414R Substitution - Missense 11:5515201-5515201 - LUAD-B00416 COSM330815 c.1277C>A p.T426K Substitution - Missense 11:5515165-5515165 - TCGA-FW-A3R5-06 COSM3869379 c.570C>T p.F190F Substitution - coding silent 11:5515872-5515872 - TCGA-EE-A2MQ-06 COSM3448922 c.354G>A p.T118T Substitution - coding silent 11:5516088-5516088 - VCB-PH-02T COSM4770627 c.189C>G p.F63L Substitution - Missense 11:5516253-5516253 - LAU50_2 COSM233701 c.169G>A p.E57K Substitution - Missense 11:5516273-5516273 - LP6005334-DNA_D03 COSM4194501 c.39G>A p.Q13Q Substitution - coding silent 11:5516403-5516403 - Mx43 COSM50357 c.1091C>T p.S364F Substitution - Missense 11:5515351-5515351 - TCGA-EE-A2MR-06 COSM3448922 c.354G>A p.T118T Substitution - coding silent 11:5516088-5516088 - TCGA-A3-3320-01 COSM1135193 c.810G>A p.L270L Substitution - coding silent 11:5515632-5515632 - MOLT-4 COSM1675772 c.975G>T p.Q325H Substitution - Missense 11:5515467-5515467 - PDA_086 COSM5002826 c.988C>T p.R330* Substitution - Nonsense 11:5515454-5515454 - CSCC-55-T COSM4545203 c.372G>A p.R124R Substitution - coding silent 11:5516070-5516070 - LS180 COSM4194447 c.665T>C p.L222P Substitution - Missense 11:5515777-5515777 - YUGATOR COSM4501184 c.582C>T p.F194F Substitution - coding silent 11:5515860-5515860 - SNUH_G10_S1 COSM3927699 c.820T>C p.Y274H Substitution - Missense 11:5515622-5515622 - TCGA-EB-A5SG-06 COSM3869380 c.564G>A p.M188I Substitution - Missense 11:5515878-5515878 - cSCCP1 COSM135994 c.643C>T p.L215F Substitution - Missense 11:5515799-5515799 - ESCC_32 COSM5627995 c.409C>A p.Q137K Substitution - Missense 11:5516033-5516033 - SNUH_G73_S1 COSM3998463 c.511T>C p.C171R Substitution - Missense 11:5515931-5515931 - 46M COSM5589294 c.731C>T p.P244L Substitution - Missense 11:5515711-5515711 - YUDEDE COSM1703468 c.626_627CA>TT p.P209L Substitution - Missense 11:5515815-5515816 - 587376 COSM1231605 c.127G>T p.D43Y Substitution - Missense 11:5516315-5516315 - TCGA-EB-A5UM-01 COSM3448902 c.798G>A p.G266G Substitution - coding silent 11:5515644-5515644 - TCGA-HU-8604-01 COSM4033645 c.192A>G p.Q64Q Substitution - coding silent 11:5516250-5516250 - S02219 COSM5675562 c.81T>A p.S27S Substitution - coding silent 11:5516361-5516361 - TCGA-FS-A1Z3-06 COSM3448898 c.1191G>T p.K397N Substitution - Missense 11:5515251-5515251 - CSCC-49-T COSM3448921 c.389G>A p.G130E Substitution - Missense 11:5516053-5516053 - C135 COSM4617142 c.15C>T p.I5I Substitution - coding silent 11:5516427-5516427 - TCGA-EE-A2GC-06 COSM3448925 c.83C>T p.S28L Substitution - Missense 11:5516359-5516359 - TCGA-BR-8369-01 COSM4033644 c.503A>G p.H168R Substitution - Missense 11:5515939-5515939 - HT55 COSM4194436 c.1259A>T p.Q420L Substitution - Missense 11:5515183-5515183 - T3091 COSM1675774 c.7C>A p.H3N Substitution - Missense 11:5516435-5516435 - SNUH_G73_S1 COSM3927699 c.820T>C p.Y274H Substitution - Missense 11:5515622-5515622 - CPCG0184-P2 COSM3927699 c.820T>C p.Y274H Substitution - Missense 11:5515622-5515622 - 0093_CRUK_PC_0093_T1_DNA COSM4420181 c.1124G>A p.R375Q Substitution - Missense 11:5515318-5515318 - TARGET-30-PARDCK COSM1288804 c.74A>T p.N25I Substitution - Missense 11:5516368-5516368 - UM-SCC-4 COSM4599777 c.698C>T p.A233V Substitution - Missense 11:5515744-5515744 - Gp2D COSM4626836 c.718C>T p.Q240* Substitution - Nonsense 11:5515724-5515724 - YUPAER COSM5372712 c.158_159GG>AA p.R53K Substitution - Missense 11:5516283-5516284 - TCGA-EE-A2MF-06 COSM4893168 c.565G>A p.E189K Substitution - Missense 11:5515877-5515877 - LIS07PT2 COSM1732597 c.669G>T p.L223F Substitution - Missense 11:5515773-5515773 - TCGA-EI-6512-01 COSM3415949 c.207A>C p.Q69H Substitution - Missense 11:5516235-5516235 - TCGA-DA-A1IC-06 COSM3448908 c.558C>T p.S186S Substitution - coding silent 11:5515884-5515884 - TCGA-EJ-5519-01 COSM1127762 c.634T>A p.S212T Substitution - Missense 11:5515808-5515808 - C058 COSM5525782 c.265G>A p.G89S Substitution - Missense 11:5516177-5516177 - TCGA-AP-A0LM-01 COSM928040 c.1187A>G p.Y396C Substitution - Missense 11:5515255-5515255 - TCGA-EE-A2MR-06 COSM3448899 c.1004G>A p.S335N Substitution - Missense 11:5515438-5515438 - SNUH_G10_S1 COSM3998463 c.511T>C p.C171R Substitution - Missense 11:5515931-5515931 - TCGA-FW-A3R5-06 COSM3869378 c.589G>A p.E197K Substitution - Missense 11:5515853-5515853 - CPCG0183-P2 COSM3927699 c.820T>C p.Y274H Substitution - Missense 11:5515622-5515622 - SNUH_G10_S1 COSM3998461 c.1257G>A p.E419E Substitution - coding silent 11:5515185-5515185 - TCGA-D7-6527-01 COSM4033632 c.708A>G p.Q236Q Substitution - coding silent 11:5515734-5515734 - 587302 COSM1231603 c.630A>C p.E210D Substitution - Missense 11:5515812-5515812 - CSCC-32-T COSM4451594 c.1307A>G p.N436S Substitution - Missense 11:5515135-5515135 - TCGA-D3-A2JF-06 COSM3448903 c.635C>T p.S212F Substitution - Missense 11:5515807-5515807 - Au1 COSM5597832 c.734C>T p.S245L Substitution - Missense 11:5515708-5515708 - 35M COSM5582980 c.926C>T p.S309L Substitution - Missense 11:5515516-5515516 - TCGA-ED-A459-01 COSM4935766 c.102A>T p.I34I Substitution - coding silent 11:5516340-5516340 - 8061103 COSM3769340 c.1017C>A p.F339L Substitution - Missense 11:5515425-5515425 - T368 COSM3448900 c.975G>A p.Q325Q Substitution - coding silent 11:5515467-5515467 - CSCC-11-T COSM4542139 c.312G>A p.Q104Q Substitution - coding silent 11:5516130-5516130 - U251 COSM1675774 c.7C>A p.H3N Substitution - Missense 11:5516435-5516435 - SNUH_G76_S1 COSM147120 c.824C>T p.A275V Substitution - Missense 11:5515618-5515618 - TCGA-ER-A19N-06 COSM3448920 c.447C>T p.A149A Substitution - coding silent 11:5515995-5515995 - 19 COSM466921 c.19C>T p.R7* Substitution - Nonsense 11:5516423-5516423 - YUDAB COSM1703467 c.835G>A p.D279N Substitution - Missense 11:5515607-5515607 - 262LT COSM147120 c.824C>T p.A275V Substitution - Missense 11:5515618-5515618 - 2334196 COSM324161 c.401G>C p.R134T Substitution - Missense 11:5516041-5516041 - HCC009T COSM5819935 c.1146C>G p.A382A Substitution - coding silent 11:5515296-5515296 - TCGA-D5-6533-01 COSM1354414 c.802A>T p.N268Y Substitution - Missense 11:5515640-5515640 - ESO-0079 COSM1269651 c.630A>G p.E210E Substitution - coding silent 11:5515812-5515812 - TCGA-FW-A3R5-06 COSM3869384 c.335C>T p.S112F Substitution - Missense 11:5516107-5516107 - TCGA-G9-6353-01 COSM3670789 c.1167C>A p.T389T Substitution - coding silent 11:5515275-5515275 - TCGA-EI-6882-01 COSM3415950 c.37C>T p.Q13* Substitution - Nonsense 11:5516405-5516405 - TCGA-AG-3581-01 COSM287867 c.638G>A p.R213H Substitution - Missense 11:5515804-5515804 - VCB-PH-02T COSM4770628 c.150C>G p.I50M Substitution - Missense 11:5516292-5516292 - HDC87 COSM4636846 c.898G>T p.G300* Substitution - Nonsense 11:5515544-5515544 - TCGA-66-2773-01 COSM688953 c.663C>T p.I221I Substitution - coding silent 11:5515779-5515779 - TCGA-EE-A3AA-06 COSM3448897 c.1302G>A p.M434I Substitution - Missense 11:5515140-5515140 - SNU-C2B COSM4194492 c.289T>C p.Y97H Substitution - Missense 11:5516153-5516153 - CSCC-11-T COSM4488714 c.336C>T p.S112S Substitution - coding silent 11:5516106-5516106 - TCGA-BS-A0UF-01 COSM928048 c.655T>G p.S219A Substitution - Missense 11:5515787-5515787 - LUAD-CHTN-MAD06-00668 COSM358492 c.783G>A p.E261E Substitution - coding silent 11:5515659-5515659 - CSCC-11-T COSM1703467 c.835G>A p.D279N Substitution - Missense 11:5515607-5515607 - LAU50_1 COSM233701 c.169G>A p.E57K Substitution - Missense 11:5516273-5516273 - TCGA-AH-6897-01 COSM3415948 c.682C>A p.L228M Substitution - Missense 11:5515760-5515760 - TCGA-AX-A060-01 COSM928045 c.982G>A p.A328T Substitution - Missense 11:5515460-5515460 - 587316 COSM1231604 c.65C>A p.A22E Substitution - Missense 11:5516377-5516377 - YURAY COSM5372713 c.99G>A p.V33V Substitution - coding silent 11:5516343-5516343 - GC8_T COSM147120 c.824C>T p.A275V Substitution - Missense 11:5515618-5515618 - XHDG38 COSM3927699 c.820T>C p.Y274H Substitution - Missense 11:5515622-5515622 - TCGA-CD-8536-01 COSM4033631 c.1170G>A p.Q390Q Substitution - coding silent 11:5515272-5515272 - CSCC-31-T COSM4501184 c.582C>T p.F194F Substitution - coding silent 11:5515860-5515860 - TCGA-B5-A0JY-01 COSM928042 c.1159G>A p.E387K Substitution - Missense 11:5515283-5515283 - TCGA-GF-A6C9-06 COSM4629759 c.557C>T p.S186F Substitution - Missense 11:5515885-5515885 - HCT15 COSM1675773 c.686C>A p.A229D Substitution - Missense 11:5515756-5515756 - ESO03T COSM1171804 c.961G>A p.D321N Substitution - Missense 11:5515481-5515481 - PT46 COSM5929350 c.1112T>G p.I371S Substitution - Missense 11:5515330-5515330 - Hx206 COSM50358 c.937C>T p.P313S Substitution - Missense 11:5515505-5515505 - TCGA-DA-A3F3-06 COSM3869385 c.222C>T p.F74F Substitution - coding silent 11:5516220-5516220 - CSCC-31-T COSM3869384 c.335C>T p.S112F Substitution - Missense 11:5516107-5516107 - TCGA-D5-6540-01 COSM1354407 c.1167C>T p.T389T Substitution - coding silent 11:5515275-5515275 - sysucc-1370T COSM5469641 c.145G>A p.D49N Substitution - Missense 11:5516297-5516297 - TCGA-HU-A4GP-01 COSM4033635 c.586T>C p.S196P Substitution - Missense 11:5515856-5515856 - TCGA-EE-A2A2-06 COSM3448919 c.472A>G p.K158E Substitution - Missense 11:5515970-5515970 - TCGA-B0-5077-01 COSM466921 c.19C>T p.R7* Substitution - Nonsense 11:5516423-5516423 - ESCC-219T COSM3935500 c.449A>G p.H150R Substitution - Missense 11:5515993-5515993 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.10653;Hs.10688 11p15.4 2467597|CGAP|BC012183|C/T|non-coding||2145|Validated; 2467597|CGAP|BC034977|C/T|non-coding||2254|Validated

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A T Missense p.S212T c.634T>A 11 5537038 PRAD C A Missense p.G93V c.278G>T 11 5537394 CM C A Missense p.K397N c.1191G>T 11 5536481 CM C A Missense p.L60F c.180G>T 11 5537492 LUAD C A Missense p.V401F c.1201G>T 11 5536471 HNSC C A Missense p.V71L c.211G>T 11 5537461 LUAD C A Nonsense p.E227* c.679G>T 11 5536993 STAD C G Missense p.R134T c.401G>C 11 5537271 SCLC C G Missense p.W456S c.1367G>C 11 5536305 CM C T Missense p.A328T c.982G>A 11 5536690 UCEC C T Missense p.E170K c.508G>A 11 5537164 CM C T Missense p.E189K c.565G>A 11 5537107 CM C T Missense p.G130E c.389G>A 11 5537283 CM C T Missense p.M234I c.702G>A 11 5536970 CM C T Missense p.M429I c.1287G>A 11 5536385 CM C T Missense p.R114Q c.341G>A 11 5537331 CM C T Missense p.R213H c.638G>A 11 5537034 COREAD G A Missense p.L473F c.1417C>T 11 5536255 CM G A Missense p.S212F c.635C>T 11 5537037 CM G A Missense p.S28L c.83C>T 11 5537589 CM G A Missense p.S308F c.923C>T 11 5536749 CM G A Nonsense p.R7* c.19C>T 11 5537653 RCCC G C Missense p.L199V c.595C>G 11 5537077 COREAD G C Missense p.R32G c.94C>G 11 5537578 HNSC GG AA Missense p.Q64* c.189_190delinsTT 11 5537482 CM G T Missense p.D23E c.69C>A 11 5537603 LUAD G T Missense p.P381T c.1141C>A 11 5536531 LUSC T A Missense p.K158N c.474A>T 11 5537198 HNSC T A Missense p.N25I c.74A>T 11 5537598 NB T A Missense p.S369C c.1105A>T 11 5536567 SCLC T A Missense p.T161S c.481A>T 11 5537191 LUSC T A Missense p.T31S c.91A>T 11 5537581 LUSC T C Missense p.I34M c.102A>G 11 5537570 STAD T C Missense p.K129E c.385A>G 11 5537287 LUSC T C Missense p.K158E c.472A>G 11 5537200 CM T G Missense p.E210D c.630A>C 11 5537042 CM T G Missense p.I332L c.994A>C 11 5536678 LUAD T G Missense p.I34L c.100A>C 11 5537572 LUAD T G Missense p.Q243H c.729A>C 11 5536943 COREAD