PTM - CPLM Gene Name UniProt ID Type Position Code ANAPC2; APC2; KIAA1406 Q9UJX6 Ubiquitination 134 K ANAPC2; APC2; KIAA1406 Q9UJX6 Ubiquitination 228 K ANAPC2; APC2; KIAA1406 Q9UJX6 Ubiquitination 190 K ANAPC2; APC2; KIAA1406 Q9UJX6 Ubiquitination 630 K ANAPC2; APC2; KIAA1406 Q9UJX6 Ubiquitination 625 K ANAPC2; APC2; KIAA1406 Q9UJX6 Ubiquitination 686 K ANAPC2; APC2; KIAA1406 Q9UJX6 Ubiquitination 562 K ANAPC2; APC2; KIAA1406 Q9UJX6 Ubiquitination 546 K

PTM - dbPAF Gene Name UniProt ID Position Type Species ANAPC2; APC2; KIAA1406 Q9UJX6 218 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 314 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 320 T Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 346 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 354 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 377 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 393 T Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 443 T Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 466 T Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 470 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 474 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 492 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 498 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 507 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 509 Y Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 511 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 532 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 534 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 732 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 736 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 738 S Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 810 Y Homo sapiens(Human) ANAPC2; APC2; KIAA1406 Q9UJX6 811 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9UJX6 R720-m2 Methylation FSVIEEErPQDRDNM Q9UJX6 S218-p Phosphorylation RYYRLLQsPLCAGCS Q9UJX6 S314-p Phosphorylation DGPARPAsPEAGNtL Q9UJX6 T320-p Phosphorylation AsPEAGNtLRRWRCH Q9UJX6 S346-p Phosphorylation LRIEELFsIVRDFPD Q9UJX6 S354-p Phosphorylation IVRDFPDsRPAIEDL Q9UJX6 S377-p Phosphorylation QRQQLLVsLKAALET Q9UJX6 T393-p Phosphorylation LLHPGVNtCDIITLY Q9UJX6 T443-p Phosphorylation RQIVAGLtGDSDGTG Q9UJX6 T466-p Phosphorylation TDPASLEtGQDsEDD Q9UJX6 S470-p Phosphorylation SLEtGQDsEDDsGEP Q9UJX6 S474-p Phosphorylation GQDsEDDsGEPEDWV Q9UJX6 S492-p Phosphorylation VDADPGKsSSKRRsS Q9UJX6 S498-p Phosphorylation KsSSKRRsSDIISLL Q9UJX6 S507-p Phosphorylation DIISLLVsIyGsKDL Q9UJX6 Y509-p Phosphorylation ISLLVsIyGsKDLFI Q9UJX6 S511-p Phosphorylation LLVsIyGsKDLFINE Q9UJX6 S532-p Phosphorylation DRLLHQFsFsPEREI Q9UJX6 S534-p Phosphorylation LLHQFsFsPEREIRN Q9UJX6 S732-p Phosphorylation DNMVLIDsDDEsDSG Q9UJX6 S736-p Phosphorylation LIDsDDEsDSGMASQ Q9UJX6 Y810-p Phosphorylation VRDQQLVysAGVYRL Q9UJX6 S811-p Phosphorylation RDQQLVysAGVYRLP Q9UJX6 K134-ub Ubiquitination RSLELLEkWTRLGLL Q9UJX6 K190-ub Ubiquitination VYMQSKRkGEGGTDP Q9UJX6 K228-ub Ubiquitination CAGCSSDkQQCWCRQ

PTM - dbPTM UniProt ID Position Code Type Resources References Q9UJX6 218 S Phosphorylation Swiss-Prot 1010711 16964243;18669648;18691976;19413330 Q9UJX6 314 S Phosphorylation Swiss-Prot 1010711 14657031;18691976;19007248 Q9UJX6 470 S Phosphorylation Swiss-Prot 1010711 18669648;19690332 Q9UJX6 534 S Phosphorylation Swiss-Prot 1010711 14657031;18669648;18691976 Q9UJX6 218 S Phosphorylation PhosphoELM.10011 22067460;18669648;16964243 Q9UJX6 314 S Phosphorylation PhosphoELM.10011 22067460;14657031 Q9UJX6 470 S Phosphorylation PhosphoELM.10011 22067460;18669648 Q9UJX6 534 S Phosphorylation PhosphoELM.10011 22067460;18669648;14657031 Q9UJX6 732 S Phosphorylation PhosphoELM.10011 22067460 Q9UJX6 736 S Phosphorylation PhosphoELM.10011 22067460 Q9UJX6 134 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9UJX6 190 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9UJX6 218 S Phosphorylation Phosphositeplus.1010730 16964243;18420821;18669648;18691976;19664994;19664995;22067460 Q9UJX6 314 S Phosphorylation Phosphositeplus.1010730 14657031;18420821;18691976;19691289;21406692;21659604;22067460 Q9UJX6 346 S Phosphorylation Phosphositeplus.1010730 21406692 Q9UJX6 354 S Phosphorylation Phosphositeplus.1010730 18420821 Q9UJX6 470 S Phosphorylation Phosphositeplus.1010730 18669648;19690332;21659604;22067460 Q9UJX6 474 S Phosphorylation Phosphositeplus.1010730 21659604 Q9UJX6 511 S Phosphorylation Phosphositeplus.1010730 21406692 Q9UJX6 532 S Phosphorylation Phosphositeplus.1010730 18420821 Q9UJX6 534 S Phosphorylation Phosphositeplus.1010730 14657031;18420821;18669648;18691976;22067460 Q9UJX6 732 S Phosphorylation Phosphositeplus.1010730 22067460 Q9UJX6 736 S Phosphorylation Phosphositeplus.1010730 22067460 Q9UJX6 393 T Phosphorylation Phosphositeplus.1010730 18420821 Q9UJX6 509 Y Phosphorylation Phosphositeplus.1010730 21406692 Q9UJX6 218 S Phosphorylation HPRD 9.0 17322306,18669648,19413330,19664995,19664994,18691976,16964243 Q9UJX6 314 S Phosphorylation HPRD 9.0 19007248,19691289,18691976 Q9UJX6 470 S Phosphorylation HPRD 9.0 18669648,18452278 Q9UJX6 534 S Phosphorylation HPRD 9.0 18669648,18691976 Q9UJX6 736 S Phosphorylation HPRD 9.0 18452278 Q9UJX6 218 S Phosphorylation SysPTM 1.1 16964243;18691976;18669648 Q9UJX6 314 S Phosphorylation SysPTM 1.1 18691976 Q9UJX6 470 S Phosphorylation SysPTM 1.1 18669648 Q9UJX6 534 S Phosphorylation SysPTM 1.1 18669648 Q9UJX6 534 S Phosphorylation SysPTM 1.1 18691976

PTM - HPRD Symbol Position Code Type References ANAPC2 218 S Phosphorylation 17322306,18669648,19413330,19664995,19664994,18691976,16964243 ANAPC2 314 S Phosphorylation 19007248,19691289,18691976 ANAPC2 470 S Phosphorylation 18669648,18452278 ANAPC2 534 S Phosphorylation 18669648,18691976 ANAPC2 736 S Phosphorylation 18452278

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9UJX6 534 S 22067460 HTP Phosphorylation Q9UJX6 534 S 18669648 HTP Phosphorylation Q9UJX6 534 S 14657031 HTP Phosphorylation Q9UJX6 218 S 22067460 HTP Phosphorylation Q9UJX6 218 S 18669648 HTP Phosphorylation Q9UJX6 218 S 16964243 HTP Phosphorylation Q9UJX6 470 S 22067460 HTP Phosphorylation Q9UJX6 470 S 18669648 HTP Phosphorylation Q9UJX6 314 S 22067460 HTP Phosphorylation Q9UJX6 314 S 14657031 HTP Phosphorylation Q9UJX6 732 S 22067460 HTP Phosphorylation Q9UJX6 736 S 22067460 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9UJX6 218 Phosphoserine 16964243;18669648;18691976;23186163 Q9UJX6 314 Phosphoserine 18691976;23186163;14657031 Q9UJX6 470 Phosphoserine 18669648;19690332 Q9UJX6 534 Phosphoserine 18669648;23186163;14657031

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type ANAPC2 IPI00002549 S 218 YYRLLQpSPLCAGC phosphorylation ANAPC2 IPI00002549 S 314 GPARPApSPEAGNT phosphorylation ANAPC2 IPI00002549 S 534 LHQFSFpSPEREIR phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 29882 118937 - K Ubiquitination 21987572 29882 118937 - K Ubiquitination 21139048 29882 118937 - K Ubiquitination 21890473 29882 118937 - K Ubiquitination 21906983 29882 118937 - K Ubiquitination 22505724 29882 118937 - K Ubiquitination 21963094

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID ANAPC2 Homo sapiens (Human) 134 "134,SLELLEKWTRLGL" 134:21890473 ANAPC2 Homo sapiens (Human) 134 "134,SLELLEKWTRLGL" 134:21890473 ANAPC2 Homo sapiens (Human) 190; 134 "190,YMQSKRKGEGGTD; 134,SLELLEKWTRLGL" 190:21906983; 134:21890473 ANAPC2 Homo sapiens (Human) 190; 134 "190,YMQSKRKGEGGTD; 134,SLELLEKWTRLGL" 190:21906983; 134:21890473