Disease associated variation - ClinVar Allele ID Type Name RS#dbSNP Phenotype IDs Chromosome Start Stop Reference Alternate 204145 single nucleotide variant NM_001161476.1(WDR25):c.840C>A (p.Asp280Glu) 796052162 MedGen:C0023976,SNOMED CT:C0023976 14 100468038 100468038 C A 204145 single nucleotide variant NM_001161476.1(WDR25):c.840C>A (p.Asp280Glu) 796052162 MedGen:C0023976,SNOMED CT:C0023976 14 100934375 100934375 C A

Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 14 100844368 rs12897338 C T rs12897338 3.68E-05 Post-operative nausea and vomiting HPOID:0002017 NA C intron GWASdb_trait 14 100845457 rs12882934 C A rs12882934 8.74E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 14 100847707 rs2273800 A G rs2273800 1.70E-04 Multiple complex diseases HPOID:0000118 NA C missense GWASdb_trait 14 100847707 rs2273800 A G rs2273800 5.68E-05 Progressive supranuclear palsy HPOID:0000605 DOID:678 C missense GWASdb_trait 14 100847930 rs3742387 A G rs3742387 2.04E-04 Multiple complex diseases HPOID:0000118 NA G cds-synon GWASdb_trait 14 100847930 rs3742387 A G rs3742387 5.91E-05 Progressive supranuclear palsy HPOID:0000605 DOID:678 G cds-synon GWASdb_trait 14 100892749 rs941924 G A rs941924 2.05E-04 Alzheimer's disease HPOID:0002511 DOID:10652 C intron GWASdb_trait 14 100896800 rs7157695 A G rs7157695 7.74E-06 Asthma (childhood onset) HPOID:0002099 DOID:2841 G intron GWASdb_trait 14 100933029 rs4905962 T C rs4905962 3.99E-05 Serum metabolites HPOID:0011111 NA T intron GWASdb_trait 14 100936793 rs8005782 A G rs8005782 1.73E-05 Serum metabolites HPOID:0011111 NA A intron GWASdb_trait