PTM - CPLM Gene Name UniProt ID Type Position Code TBL1XR1; IRA1; TBLR1 Q9BZK7 Acetylation 254 K TBL1XR1; IRA1; TBLR1 Q9BZK7 Sumoylation 497 K TBL1XR1; IRA1; TBLR1 Q9BZK7 Ubiquitination 379 K TBL1XR1; IRA1; TBLR1 Q9BZK7 Ubiquitination 277 K TBL1XR1; IRA1; TBLR1 Q9BZK7 Ubiquitination 102 K

PTM - dbPAF Gene Name UniProt ID Position Type Species TBL1XR1; IRA1; TBLR1 Q9BZK7 119 S Homo sapiens(Human) TBL1XR1; IRA1; TBLR1 Q9BZK7 123 S Homo sapiens(Human) TBL1XR1; IRA1; TBLR1 Q9BZK7 199 S Homo sapiens(Human) TBL1XR1; IRA1; TBLR1 Q9BZK7 203 T Homo sapiens(Human) TBL1XR1; IRA1; TBLR1 Q9BZK7 204 S Homo sapiens(Human) TBL1XR1; IRA1; TBLR1 Q9BZK7 446 Y Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9BZK7 K102-ac Acetylation RQQAYRDkLAQQQAA Q9BZK7 K254-ac Acetylation GFARIWTkDGNLAST Q9BZK7 K277-ac Acetylation FALKWNKkGNFILSA Q9BZK7 R431-m1 Methylation VRLWDVDrGICIHTL Q9BZK7 K464-m1 Methylation LASGSFDkCVHIWNT Q9BZK7 S119-p Phosphorylation AAAAAAAsQQGsAKN Q9BZK7 S123-p Phosphorylation AAAsQQGsAKNGENT Q9BZK7 S199-p Phosphorylation TARIWNLsENStsGS Q9BZK7 T203-p Phosphorylation WNLsENStsGSTQLV Q9BZK7 S204-p Phosphorylation NLsENStsGSTQLVL Q9BZK7 Y446-p Phosphorylation TKHQEPVySVAFSPD Q9BZK7 K277-sm Sumoylation FALKWNKkGNFILSA Q9BZK7 K497-sm Sumoylation CWNAAGDkVGASASD Q9BZK7 K102-ub Ubiquitination RQQAYRDkLAQQQAA Q9BZK7 K277-ub Ubiquitination FALKWNKkGNFILSA Q9BZK7 K379-ub Ubiquitination TLKIWSMkQDNCVHD

PTM - dbPTM UniProt ID Position Code Type Resources References Q9BZK7 119 S Phosphorylation Swiss-Prot 1010711 17525332 Q9BZK7 254 K Acetylation Swiss-Prot 1010711 19608861 Q9BZK7 119 S Phosphorylation PhosphoELM.10011 17525332 Q9BZK7 152 D Caspase Phosphositeplus.1010730 18722006 Q9BZK7 497 K Sumoylation Phosphositeplus.1010730 21777810 Q9BZK7 102 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9BZK7 277 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9BZK7 379 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9BZK7 254 K Acetylation Phosphositeplus.1010730 19608861 Q9BZK7 119 S Phosphorylation Phosphositeplus.1010730 17525332;20068231;20164059 Q9BZK7 123 S Phosphorylation Phosphositeplus.1010730 18374649 Q9BZK7 199 S Phosphorylation Phosphositeplus.1010730 18374649 Q9BZK7 204 S Phosphorylation Phosphositeplus.1010730 18374649 Q9BZK7 203 T Phosphorylation Phosphositeplus.1010730 18374649 Q9BZK7 446 Y Phosphorylation Phosphositeplus.1010730 17360941 Q9BZK7 254 K Acetylation HPRD 9.0 19608861 Q9BZK7 119 S Phosphorylation HPRD 9.0 17525332,20068231

PTM - HPRD Symbol Position Code Type References TBL1XR1 119 S Phosphorylation 17525332,20068231 TBL1XR1 254 K Acetylation 19608861

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9BZK7 119 S 17525332 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9BZK7 2 N-acetylserine 22223895;22814378 Q9BZK7 119 Phosphoserine 20068231;23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type TBL1XR1 IPI00002922 K 254 FARIWTaKDGNLAS acetylation TBL1XR1 IPI00002922 S 119 AAAAAApSQQGSAK phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 79718 122834 - K Ubiquitination 21139048 79718 122834 - K Ubiquitination 21890473 79718 122834 - K Ubiquitination 21906983 79718 122834 - K Ubiquitination 21963094 79718 122834 - K Ubiquitination 23000965

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID TBL1XR1 Homo sapiens (Human) 102; 277; 379 "102,QQAYRDKLAQQQA; 277,ALKWNKKGNFILS; 379,LKIWSMKQDNCVH" 102:21906983; 277:21906983; 379:21890473 TBL1XR1 Homo sapiens (Human) 15 "15,QQAYRDKLAQQQA" 15:21906983 TBL1XR1 Homo sapiens (Human) 102 "102,QQAYRDKLAQQQA" 102:21906983 TBL1XR1 Homo sapiens (Human) 102 "102,QQAYRDKLAQQQA" 102:21906983