PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants A0A087X295 Q7L622 two hybrid 16189514 direct interaction X 2 A0A087X295 A0A024R475 affinity chromatography technology 21145461 physical association X 2 A0A087X295 P46531 affinity chromatography technology 23022380 physical association X 2 A0A087X295 Q15843 affinity chromatography technology 18247557 physical association X 2 A0A087X295 affinity chromatography technology 23602568 physical association X 2 P55854 A0A087X295 affinity chromatography technology 25391492 physical association X 2 Q9NRC8 A0A087X295 affinity chromatography technology 22586326 physical association X 2 O14654 A0A087X295 affinity chromatography technology 25036637 physical association X 2 O14654 A0A087X295 affinity chromatography technology 25036637 physical association X 2 A0A087X295 imaging technique 19910486 colocalization X 2 A0A087X295 two hybrid 22990118 direct interaction X 2 A0A087X295 P62993-2 affinity chromatography technology 21706016 physical association X 2 A0A087X295 Q8NE63 affinity chromatography technology 23602568 physical association X 2 A0A087X295 B7Z9V1 two hybrid 25416956 direct interaction X 2 Q13418 A0A087X295 affinity chromatography technology 23455922 physical association X 2 O14733 A0A087X295 affinity chromatography technology 19910486 physical association X 2 P50402 A0A087X295 affinity chromatography technology 23443559 physical association X 2 P0CG48 A0A087X295 affinity chromatography technology 22505724 physical association X 2 P0CG48 A0A087X295 affinity chromatography technology 21963094 physical association X 2 P0CG48 A0A087X295 affinity chromatography technology 23000965 physical association X 2 P0CG48 A0A087X295 affinity chromatography technology 25147182 physical association X 2 P0CG48 A0A087X295 affinity chromatography technology 22118674 physical association X 2 P0CG48 A0A087X295 affinity chromatography technology 21139048 physical association X 2 P0CG48 A0A087X295 affinity chromatography technology 21890473 physical association X 2 P0CG48 A0A087X295 affinity chromatography technology 21906983 physical association X 2 P00533 A0A087X295 affinity chromatography technology 24797263 physical association X 2 B2R6D8 A0A087X295 two hybrid 16189514 direct interaction X 2 O43314-2 A0A087X295 biochemical 22939629 colocalization X 2 A0A087X295 Q7L622 two hybrid 16189514 - X 2 A0A087X295 Q7L622 two hybrid 16189514 - X 2 A0A087X295 in vivo 11912194 - C 7 A0A087X295 in vivo 11912194 - C 7 A0A087X295 in vivo 11912194 - C 7 A0A087X295 in vivo 11912194 - C 7 A0A087X295 in vivo 11912194 - C 7 A0A087X295 in vivo 11912194 - C 7 A0A087X295 in vivo 11912194 - C 7 B2R6D8 A0A087X295 two hybrid 16189514 - X 2 B2R6D8 A0A087X295 two hybrid 16189514 - X 2

PPI - HINT Gene A Gene B PMID Method Quality PPIP5K2 WDR6 22939629 0401 HT RPL10 WDR6 26496610,26496610 0007,0004 HT CDC25B WDR6 26496610 0007 HT EMD WDR6 23443559 0004 HT ILK WDR6 23455922 0676 HT CUL3 WDR6 21145461 0004 HT CDC37 WDR6 26496610,26496610 0007,0004 HT MEX3C WDR6 22863774,26471122 0096,0004 LC DKFZP686G14213 WDR6 26496610 0004 HT TMEM17 WDR6 26638075,26638075 1314,1313 HT ULK2 WDR6 20562859 0007 HT HIPK4 WDR6 23602568 0004 HT RNF2 WDR6 26496610,26496610 0007,0004 HT WDR6 TMEM216 26638075,26638075 1314,1313 HT WDR6 UVRAG 20562859 0007 HT WDR6 FTSJ1 26496610,26344197,26496610 0007,0401,0004 HT WDR6 DYRK1B 23602568,23602568 0004,0676 HT WDR6 HEL-S-28 23455922 0004 HT PPIP5K2 WDR6 22939629 0401 HT RPL10 WDR6 26496610,26496610 0007,0004 HT CDC25B WDR6 26496610 0007 HT EMD WDR6 23443559 0004 HT ILK WDR6 23455922 0676 HT CUL3 WDR6 21145461 0004 HT CDC37 WDR6 26496610,26496610 0007,0004 HT DKFZP686G14213 WDR6 26496610 0004 HT TMEM17 WDR6 26638075,26638075 1314,1313 HT ULK2 WDR6 20562859 0007 HT HIPK4 WDR6 23602568 0004 HT RNF2 WDR6 26496610,26496610 0007,0004 HT WDR6 TMEM216 26638075,26638075 1314,1313 HT WDR6 UVRAG 20562859 0007 HT WDR6 FTSJ1 26496610,26344197,26496610 0007,0401,0004 HT WDR6 DYRK1B 23602568,23602568 0004,0676 HT WDR6 HEL-S-28 23455922 0004 HT MEX3C WDR6 22863774,26471122 0096,0004 LC PPIP5K2 WDR6 22939629 0401 LC ELANE WDR6 19506020 0018 LC PTPN3 WDR6 25416956,25416956,25416956 1112,0397,1356 HT BRCA1 WDR6 22990118 0018 LC STK11 WDR6 17216128,17216128,17216128,17216128 0007,0416,0004,0018 LC G2E3 WDR6 16189514,16189514 0398,0018 HT Q8N4S3 WDR6 25416956 0018 HT CDC42EP4 WDR6 16189514,16189514 0398,0018 HT WDR6 FTSJ1 26344197 0401 LC

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 IRS4 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database MAP2K7 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database BAG2 WDR6 MI:0362 inference MI:0461 interaction database EGFR WDR6 MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database UBC WDR6 MI:0045 experimental interaction detection MI:0461 interaction database PTPN3 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database RPL10 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database CDC25B WDR6 MI:0045 experimental interaction detection MI:0461 interaction database ARRB2 WDR6 MI:0362 inference MI:0461 interaction database BRCA1 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database RPL35 WDR6 MI:0362 inference MI:0461 interaction database NOTCH1 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database TMED10 WDR6 MI:0362 inference MI:0461 interaction database EMD WDR6 MI:0045 experimental interaction detection MI:0461 interaction database SUMO3 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database GRB2 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database ILK WDR6 MI:0045 experimental interaction detection MI:0461 interaction database CUL3 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database STK11 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database NEDD8 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database CDC37 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database MEX3C WDR6 MI:0045 experimental interaction detection MI:0461 interaction database TUBA1A WDR6 MI:0045 experimental interaction detection MI:0461 interaction database G2E3 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database TMEM17 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database KSR1 WDR6 MI:0362 inference MI:0461 interaction database ULK2 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database KMT2E WDR6 MI:0045 experimental interaction detection MI:0461 interaction database HIPK4 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database COPS5 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database RNF2 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database CDC42EP4 WDR6 MI:0045 experimental interaction detection MI:0461 interaction database WDR6 SIRT7 MI:0045 experimental interaction detection MI:0461 interaction database WDR6 TMEM216 MI:0045 experimental interaction detection MI:0461 interaction database WDR6 UVRAG MI:0045 experimental interaction detection MI:0461 interaction database WDR6 FTSJ1 MI:0045 experimental interaction detection MI:0461 interaction database WDR6 DYRK1B MI:0045 experimental interaction detection MI:0461 interaction database