Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 15 86312878 86312878 + Missense_Mutation SNP C C A TCGA-OR-A5KB-01A-11D-A30A-10 TCGA-OR-A5KB-11A-11D-A30A-10 g.chr15:86312878C>A c.164G>T c.(163-165)cGt>cTt p.R55L BLCA 15 86311544 86311544 + Missense_Mutation SNP C C G TCGA-S5-AA26-01A-11D-A38G-08 TCGA-S5-AA26-10A-01D-A38J-08 g.chr15:86311544C>G c.1498G>C c.(1498-1500)Gac>Cac p.D500H BLCA 15 86311830 86311830 + Silent SNP C C T TCGA-G2-A2EL-01A-12D-A18F-08 TCGA-G2-A2EL-10A-01D-A18F-08 g.chr15:86311830C>T c.1212G>A c.(1210-1212)ccG>ccA p.P404P BLCA 15 86312223 86312223 + Missense_Mutation SNP C C G TCGA-ZF-AA54-01A-11D-A391-08 TCGA-ZF-AA54-10A-01D-A394-08 g.chr15:86312223C>G c.819G>C c.(817-819)aaG>aaC p.K273N BRCA 15 86311422 86311422 + Silent SNP G G C TCGA-AC-A3W6-01A-12D-A228-09 TCGA-AC-A3W6-10A-01D-A22A-09 g.chr15:86311422G>C c.1620C>G c.(1618-1620)ctC>ctG p.L540L BRCA 15 86311723 86311723 + Missense_Mutation SNP A A C TCGA-GI-A2C8-01A-11D-A16D-09 TCGA-GI-A2C8-11A-22D-A16D-09 g.chr15:86311723A>C c.1319T>G c.(1318-1320)gTg>gGg p.V440G BRCA 15 86311929 86311929 + Silent SNP C C T TCGA-AO-A03T-01A-21W-A050-09 TCGA-AO-A03T-10A-01W-A055-09 g.chr15:86311929C>T c.1113G>A c.(1111-1113)gcG>gcA p.A371A BRCA 15 86311940 86311940 + Missense_Mutation SNP A A T TCGA-A1-A0SH-01A-11D-A099-09 TCGA-A1-A0SH-10A-03D-A099-09 g.chr15:86311940A>T c.1102T>A c.(1102-1104)Tgg>Agg p.W368R BRCA 15 86312361 86312361 + Silent SNP G G C TCGA-D8-A1JA-01A-11D-A13L-09 TCGA-D8-A1JA-10A-01W-A14R-09 g.chr15:86312361G>C c.681C>G c.(679-681)gtC>gtG p.V227V CHOL 15 86311759 86311759 + Missense_Mutation SNP G G A TCGA-W5-AA2T-01A-12D-A417-09 TCGA-W5-AA2T-10A-01D-A41A-09 g.chr15:86311759G>A c.1283C>T c.(1282-1284)gCc>gTc p.A428V COAD 15 86311339 86311339 + Missense_Mutation SNP A A G TCGA-D5-6532-01A-11D-1719-10 TCGA-D5-6532-10A-01D-1719-10 g.chr15:86311339A>G c.1703T>C c.(1702-1704)aTc>aCc p.I568T COAD 15 86311413 86311413 + Silent SNP G G A TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr15:86311413G>A c.1629C>T c.(1627-1629)gtC>gtT p.V543V COAD 15 86311513 86311513 + Missense_Mutation SNP C C T TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr15:86311513C>T c.1529G>A c.(1528-1530)cGc>cAc p.R510H COAD 15 86311588 86311588 + Missense_Mutation SNP G G A TCGA-F4-6570-01A-11D-1771-10 TCGA-F4-6570-10A-01D-1771-10 g.chr15:86311588G>A c.1454C>T c.(1453-1455)aCa>aTa p.T485I COAD 15 86311930 86311930 + Missense_Mutation SNP G G A TCGA-A6-5665-01A-01D-1650-10 TCGA-A6-5665-10A-01D-1650-10 g.chr15:86311930G>A c.1112C>T c.(1111-1113)gCg>gTg p.A371V COAD 15 86312074 86312074 + Missense_Mutation SNP T T C TCGA-AA-3662-01A-01D-1719-10 TCGA-AA-3662-11A-01D-1719-10 g.chr15:86312074T>C c.968A>G c.(967-969)aAg>aGg p.K323R COAD 15 86312255 86312255 + Nonsense_Mutation SNP T T A TCGA-G4-6626-01A-11D-1771-10 TCGA-G4-6626-10A-01D-1771-10 g.chr15:86312255T>A c.787A>T c.(787-789)Aag>Tag p.K263* COAD 15 86312482 86312482 + Missense_Mutation SNP C C T TCGA-AA-3713-01A-21D-1719-10 TCGA-AA-3713-11A-01D-1719-10 g.chr15:86312482C>T c.560G>A c.(559-561)aGc>aAc p.S187N COAD 15 86312570 86312570 + Missense_Mutation SNP C C T TCGA-AA-A01R-01A-21W-A096-10 TCGA-AA-A01R-11A-12W-A096-10 g.chr15:86312570C>T c.472G>A c.(472-474)Gcc>Acc p.A158T COAD 15 86312608 86312608 + Frame_Shift_Del DEL A A - TCGA-AA-3710-01A-01W-0995-10 TCGA-AA-3710-10A-01W-0995-10 g.chr15:86312608delA c.434delT c.(433-435)ttcfs p.F145fs COAD 15 86312616 86312616 + Missense_Mutation SNP C C A TCGA-AA-3510-01A-01D-1408-10 TCGA-AA-3510-11A-01D-1408-10 g.chr15:86312616C>A c.426G>T c.(424-426)aaG>aaT p.K142N COAD 15 86312670 86312670 + Silent SNP G G A TCGA-AA-3712-01A-21D-1719-10 TCGA-AA-3712-11A-01D-1719-10 g.chr15:86312670G>A c.372C>T c.(370-372)ggC>ggT p.G124G COAD 15 86312711 86312711 + Missense_Mutation SNP C C T TCGA-AA-3672-01A-01W-0900-09 TCGA-AA-3672-10A-01W-0900-09 g.chr15:86312711C>T c.331G>A c.(331-333)Gcc>Acc p.A111T COAD 15 86312809 86312809 + Missense_Mutation SNP C C T TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr15:86312809C>T c.233G>A c.(232-234)gGc>gAc p.G78D COAD 15 86312824 86312824 + Missense_Mutation SNP G G A TCGA-AA-3715-01A-01W-0900-09 TCGA-AA-3715-10A-01W-0900-09 g.chr15:86312824G>A c.218C>T c.(217-219)gCc>gTc p.A73V COAD 15 86312901 86312901 + Silent SNP G G A TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr15:86312901G>A c.141C>T c.(139-141)gaC>gaT p.D47D COADREAD 15 86311339 86311339 + Missense_Mutation SNP A A G TCGA-D5-6532-01A-11D-1719-10 TCGA-D5-6532-10A-01D-1719-10 g.chr15:86311339A>G c.1703T>C c.(1702-1704)aTc>aCc p.I568T COADREAD 15 86311413 86311413 + Silent SNP G G A TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr15:86311413G>A c.1629C>T c.(1627-1629)gtC>gtT p.V543V COADREAD 15 86311513 86311513 + Missense_Mutation SNP C C T TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr15:86311513C>T c.1529G>A c.(1528-1530)cGc>cAc p.R510H COADREAD 15 86311588 86311588 + Missense_Mutation SNP G G A TCGA-F4-6570-01A-11D-1771-10 TCGA-F4-6570-10A-01D-1771-10 g.chr15:86311588G>A c.1454C>T c.(1453-1455)aCa>aTa p.T485I COADREAD 15 86311930 86311930 + Missense_Mutation SNP G G A TCGA-A6-5665-01A-01D-1650-10 TCGA-A6-5665-10A-01D-1650-10 g.chr15:86311930G>A c.1112C>T c.(1111-1113)gCg>gTg p.A371V COADREAD 15 86312074 86312074 + Missense_Mutation SNP T T C TCGA-AA-3662-01A-01D-1719-10 TCGA-AA-3662-11A-01D-1719-10 g.chr15:86312074T>C c.968A>G c.(967-969)aAg>aGg p.K323R COADREAD 15 86312255 86312255 + Nonsense_Mutation SNP T T A TCGA-G4-6626-01A-11D-1771-10 TCGA-G4-6626-10A-01D-1771-10 g.chr15:86312255T>A c.787A>T c.(787-789)Aag>Tag p.K263* COADREAD 15 86312482 86312482 + Missense_Mutation SNP C C T TCGA-AA-3713-01A-21D-1719-10 TCGA-AA-3713-11A-01D-1719-10 g.chr15:86312482C>T c.560G>A c.(559-561)aGc>aAc p.S187N COADREAD 15 86312570 86312570 + Missense_Mutation SNP C C T TCGA-AA-A01R-01A-21W-A096-10 TCGA-AA-A01R-11A-12W-A096-10 g.chr15:86312570C>T c.472G>A c.(472-474)Gcc>Acc p.A158T COADREAD 15 86312608 86312608 + Frame_Shift_Del DEL A A - TCGA-AA-3710-01A-01W-0995-10 TCGA-AA-3710-10A-01W-0995-10 g.chr15:86312608delA c.434delT c.(433-435)ttcfs p.F145fs COADREAD 15 86312616 86312616 + Missense_Mutation SNP C C A TCGA-AA-3510-01A-01D-1408-10 TCGA-AA-3510-11A-01D-1408-10 g.chr15:86312616C>A c.426G>T c.(424-426)aaG>aaT p.K142N COADREAD 15 86312670 86312670 + Silent SNP G G A TCGA-AA-3712-01A-21D-1719-10 TCGA-AA-3712-11A-01D-1719-10 g.chr15:86312670G>A c.372C>T c.(370-372)ggC>ggT p.G124G COADREAD 15 86312711 86312711 + Missense_Mutation SNP C C T TCGA-AA-3672-01A-01W-0900-09 TCGA-AA-3672-10A-01W-0900-09 g.chr15:86312711C>T c.331G>A c.(331-333)Gcc>Acc p.A111T COADREAD 15 86312809 86312809 + Missense_Mutation SNP C C T TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr15:86312809C>T c.233G>A c.(232-234)gGc>gAc p.G78D COADREAD 15 86312824 86312824 + Missense_Mutation SNP G G A TCGA-AA-3715-01A-01W-0900-09 TCGA-AA-3715-10A-01W-0900-09 g.chr15:86312824G>A c.218C>T c.(217-219)gCc>gTc p.A73V COADREAD 15 86312901 86312901 + Silent SNP G G A TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr15:86312901G>A c.141C>T c.(139-141)gaC>gaT p.D47D COADREAD 15 86312925 86312925 + Silent SNP A A G TCGA-DY-A1DG-01A-11D-A152-10 TCGA-DY-A1DG-10A-01D-A152-10 g.chr15:86312925A>G c.117T>C c.(115-117)ctT>ctC p.L39L ESCA 15 86311930 86311930 + Missense_Mutation SNP G G A TCGA-Z6-A8JE-01A-11D-A37C-09 TCGA-Z6-A8JE-10A-01D-A37F-09 g.chr15:86311930G>A c.1112C>T c.(1111-1113)gCg>gTg p.A371V ESCA 15 86312008 86312008 + Missense_Mutation SNP G G A TCGA-L5-A43J-01A-12D-A247-09 TCGA-L5-A43J-11A-11D-A247-09 g.chr15:86312008G>A c.1034C>T c.(1033-1035)aCg>aTg p.T345M GBMLGG 15 86311637 86311637 + Missense_Mutation SNP C C T TCGA-HT-7857-01A-11D-2395-08 TCGA-HT-7857-10A-01D-2396-08 g.chr15:86311637C>T c.1405G>A c.(1405-1407)Gag>Aag p.E469K GBMLGG 15 86312002 86312002 + Missense_Mutation SNP C C T TCGA-FG-A60L-01A-12D-A31L-08 TCGA-FG-A60L-10A-01D-A31J-08 g.chr15:86312002C>T c.1040G>A c.(1039-1041)gGc>gAc p.G347D GBMLGG 15 86312652 86312652 + Silent SNP G G A TCGA-HT-7608-01A-11D-2086-08 TCGA-HT-7608-10A-01D-2086-08 g.chr15:86312652G>A c.390C>T c.(388-390)caC>caT p.H130H HNSC 15 86311486 86311486 + Missense_Mutation SNP G G A TCGA-CN-4725-01A-01D-1434-08 TCGA-CN-4725-10A-01D-1434-08 g.chr15:86311486G>A c.1556C>T c.(1555-1557)aCg>aTg p.T519M HNSC 15 86311556 86311556 + Missense_Mutation SNP T T A TCGA-CV-6941-01A-11D-1912-08 TCGA-CV-6941-10A-01D-1912-08 g.chr15:86311556T>A c.1486A>T c.(1486-1488)Atc>Ttc p.I496F HNSC 15 86311590 86311605 + Frame_Shift_Del DEL GTACCGCCAAGGCTGG GTACCGCCAAGGCTGG - TCGA-CV-5978-01A-11D-1683-08 TCGA-CV-5978-11A-01D-1683-08 g.chr15:86311590_86311605delGTACCGCCAAGGCTGG c.1437_1452delCCAGCCTTGGCGGTAC c.(1435-1452)ccccagccttggcggtacfs p.PQPWRY479fs HNSC 15 86312264 86312264 + Nonsense_Mutation SNP C C A TCGA-CR-7364-01A-11D-2012-08 TCGA-CR-7364-10A-01D-2013-08 g.chr15:86312264C>A c.778G>T c.(778-780)Gag>Tag p.E260* HNSC 15 86312285 86312285 + Missense_Mutation SNP C C T TCGA-CN-6022-01A-21D-1683-08 TCGA-CN-6022-10A-01D-1683-08 g.chr15:86312285C>T c.757G>A c.(757-759)Gag>Aag p.E253K HNSC 15 86312316 86312316 + Silent SNP C C T TCGA-P3-A6SW-01A-11D-A34J-08 TCGA-P3-A6SW-10A-01D-A34M-08 g.chr15:86312316C>T c.726G>A c.(724-726)ccG>ccA p.P242P HNSC 15 86312712 86312712 + Silent SNP G G A TCGA-HD-8635-01A-11D-2394-08 TCGA-HD-8635-10A-01D-2394-08 g.chr15:86312712G>A c.330C>T c.(328-330)atC>atT p.I110I HNSC 15 86312762 86312762 + Missense_Mutation SNP G G T TCGA-CQ-6219-01A-11D-1912-08 TCGA-CQ-6219-10A-01D-1912-08 g.chr15:86312762G>T c.280C>A c.(280-282)Cac>Aac p.H94N KIPAN 15 86311567 86311567 + Missense_Mutation SNP C C A TCGA-CJ-4913-01A-01D-1429-08 TCGA-CJ-4913-11A-01D-1429-08 g.chr15:86311567C>A c.1475G>T c.(1474-1476)aGc>aTc p.S492I KIPAN 15 86312287 86312287 + Missense_Mutation SNP C C T TCGA-A3-3323-01A-01D-0966-08 TCGA-A3-3323-11A-01D-0966-08 g.chr15:86312287C>T c.755G>A c.(754-756)aGc>aAc p.S252N KIPAN 15 86312584 86312584 + Missense_Mutation SNP A A G TCGA-B0-4818-01A-01D-1501-10 TCGA-B0-4818-11A-01D-1501-10 g.chr15:86312584A>G c.458T>C c.(457-459)aTg>aCg p.M153T KIRC 15 86311567 86311567 + Missense_Mutation SNP C C A TCGA-CJ-4913-01A-01D-1429-08 TCGA-CJ-4913-11A-01D-1429-08 g.chr15:86311567C>A c.1475G>T c.(1474-1476)aGc>aTc p.S492I KIRC 15 86312287 86312287 + Missense_Mutation SNP C C T TCGA-A3-3323-01A-01D-0966-08 TCGA-A3-3323-11A-01D-0966-08 g.chr15:86312287C>T c.755G>A c.(754-756)aGc>aAc p.S252N KIRC 15 86312584 86312584 + Missense_Mutation SNP A A G TCGA-B0-4818-01A-01D-1501-10 TCGA-B0-4818-11A-01D-1501-10 g.chr15:86312584A>G c.458T>C c.(457-459)aTg>aCg p.M153T LGG 15 86311637 86311637 + Missense_Mutation SNP C C T TCGA-HT-7857-01A-11D-2395-08 TCGA-HT-7857-10A-01D-2396-08 g.chr15:86311637C>T c.1405G>A c.(1405-1407)Gag>Aag p.E469K LGG 15 86312002 86312002 + Missense_Mutation SNP C C T TCGA-FG-A60L-01A-12D-A31L-08 TCGA-FG-A60L-10A-01D-A31J-08 g.chr15:86312002C>T c.1040G>A c.(1039-1041)gGc>gAc p.G347D LGG 15 86312652 86312652 + Silent SNP G G A TCGA-HT-7608-01A-11D-2086-08 TCGA-HT-7608-10A-01D-2086-08 g.chr15:86312652G>A c.390C>T c.(388-390)caC>caT p.H130H LIHC 15 86312123 86312123 + Missense_Mutation SNP A A G TCGA-DD-A39Y-01A-11D-A20W-10 TCGA-DD-A39Y-11A-11D-A20W-10 g.chr15:86312123A>G c.919T>C c.(919-921)Tgt>Cgt p.C307R LUAD 15 86311278 86311278 + Silent SNP G G A TCGA-86-8585-01A-11D-2393-08 TCGA-86-8585-10A-01D-2393-08 g.chr15:86311278G>A c.1764C>T c.(1762-1764)ccC>ccT p.P588P LUAD 15 86312160 86312160 + Silent SNP G G T TCGA-49-6743-01A-11D-1855-08 TCGA-49-6743-11A-01D-1855-08 g.chr15:86312160G>T c.882C>A c.(880-882)ggC>ggA p.G294G LUAD 15 86312336 86312336 + Missense_Mutation SNP C C T TCGA-55-8506-01A-11D-2393-08 TCGA-55-8506-10A-01D-2393-08 g.chr15:86312336C>T c.706G>A c.(706-708)Gtg>Atg p.V236M LUAD 15 86312943 86312943 + Silent SNP C C T TCGA-17-Z055-01A-01W-0747-08 TCGA-17-Z055-11A-01W-0747-08 g.chr15:86312943C>T c.99G>A c.(97-99)ctG>ctA p.L33L LUSC 15 86311564 86311564 + Missense_Mutation SNP T T C TCGA-60-2724-01A-01D-1522-08 TCGA-60-2724-11A-01D-1522-08 g.chr15:86311564T>C c.1478A>G c.(1477-1479)cAg>cGg p.Q493R LUSC 15 86312069 86312069 + Missense_Mutation SNP C C A TCGA-21-1071-01A-01D-1521-08 TCGA-21-1071-11A-01D-1521-08 g.chr15:86312069C>A c.973G>T c.(973-975)Gac>Tac p.D325Y OV 15 86311340 86311340 + Missense_Mutation SNP T T C TCGA-13-0924-01A-01W-0421-09 TCGA-13-0924-10A-01W-0421-09 g.chr15:86311340T>C c.1702A>G c.(1702-1704)Atc>Gtc p.I568V OV 15 86312927 86312927 + Missense_Mutation SNP G G A TCGA-13-1505-01A-01D-0472-08 TCGA-13-1505-10A-01D-0472-08 g.chr15:86312927G>A c.115C>T c.(115-117)Ctt>Ttt p.L39F PAAD 15 86311613 86311613 + Missense_Mutation SNP C C T TCGA-IB-AAUM-01A-11D-A377-08 TCGA-IB-AAUM-10A-01D-A37A-08 g.chr15:86311613C>T c.1429G>A c.(1429-1431)Gag>Aag p.E477K PRAD 15 86312337 86312337 + Silent SNP G G A TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr15:86312337G>A c.705C>T c.(703-705)agC>agT p.S235S READ 15 86312925 86312925 + Silent SNP A A G TCGA-DY-A1DG-01A-11D-A152-10 TCGA-DY-A1DG-10A-01D-A152-10 g.chr15:86312925A>G c.117T>C c.(115-117)ctT>ctC p.L39L SKCM 15 86311557 86311557 + Silent SNP G G A TCGA-EE-A3AD-06A-11D-A196-08 TCGA-EE-A3AD-10A-01D-A198-08 g.chr15:86311557G>A c.1485C>T c.(1483-1485)ttC>ttT p.F495F SKCM 15 86312345 86312345 + Missense_Mutation SNP G G A TCGA-D3-A51T-06A-11D-A25O-08 TCGA-D3-A51T-10A-01D-A25O-08 g.chr15:86312345G>A c.697C>T c.(697-699)Ctc>Ttc p.L233F SKCM 15 86312415 86312415 + Silent SNP C C T TCGA-EE-A2MF-06A-11D-A21A-08 TCGA-EE-A2MF-10B-01D-A21A-08 g.chr15:86312415C>T c.627G>A c.(625-627)gtG>gtA p.V209V

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BOCA-FR 15 86308019 86308019 single base substitution G T intron_variant BOCA-FR 15 86315605 86315605 single base substitution C T intron_variant BRCA-EU 15 86298659 86298659 single base substitution G T downstream_gene_variant BRCA-EU 15 86302183 86302183 deletion of <=200bp G - downstream_gene_variant BRCA-EU 15 86305023 86305023 single base substitution G T intron_variant BRCA-EU 15 86305095 86305095 single base substitution G C intron_variant BRCA-EU 15 86305260 86305260 single base substitution C T intron_variant BRCA-EU 15 86306558 86306558 single base substitution C T intron_variant BRCA-EU 15 86306746 86306746 single base substitution G A intron_variant BRCA-EU 15 86308318 86308318 single base substitution C A intron_variant BRCA-EU 15 86308594 86308594 single base substitution C A intron_variant BRCA-EU 15 86309923 86309923 single base substitution C T intron_variant BRCA-EU 15 86311894 86311894 single base substitution G T intron_variant BRCA-EU 15 86311894 86311894 single base substitution G T stop_gained S383* 1148C>A BRCA-EU 15 86312941 86312941 single base substitution G A intron_variant BRCA-EU 15 86312941 86312941 single base substitution G A missense_variant A34V 101C>T BRCA-EU 15 86315058 86315058 single base substitution C A intron_variant BRCA-EU 15 86316006 86316006 single base substitution C A intron_variant BRCA-EU 15 86317438 86317438 single base substitution T G intron_variant BRCA-EU 15 86318002 86318002 single base substitution G A intron_variant BRCA-EU 15 86322407 86322407 single base substitution G A intron_variant BRCA-EU 15 86323088 86323088 single base substitution C A intron_variant BRCA-EU 15 86323386 86323386 single base substitution G A intron_variant BRCA-EU 15 86324456 86324472 deletion of <=200bp CTCAGTGGCATTCCCAT - intron_variant BRCA-EU 15 86327572 86327572 single base substitution C T intron_variant BRCA-EU 15 86328395 86328395 single base substitution G A intron_variant BRCA-EU 15 86328966 86328966 single base substitution G C intron_variant BRCA-EU 15 86330791 86330791 insertion of <=200bp - AA intron_variant BRCA-EU 15 86330795 86330795 single base substitution T A intron_variant BRCA-EU 15 86331902 86331902 single base substitution C T intron_variant BRCA-EU 15 86332864 86332864 single base substitution C A intron_variant BRCA-EU 15 86335657 86335657 single base substitution G A intron_variant BRCA-EU 15 86337658 86337658 single base substitution A T intron_variant BRCA-EU 15 86339522 86339522 single base substitution C A upstream_gene_variant BRCA-EU 15 86340734 86340734 single base substitution G C upstream_gene_variant BRCA-FR 15 86305023 86305023 single base substitution G T intron_variant BRCA-FR 15 86306558 86306558 single base substitution C T intron_variant BRCA-FR 15 86322407 86322407 single base substitution G A intron_variant BRCA-FR 15 86323386 86323386 single base substitution G A intron_variant BRCA-FR 15 86340734 86340734 single base substitution G C upstream_gene_variant BRCA-UK 15 86342108 86342108 single base substitution G C upstream_gene_variant BRCA-US 15 86311422 86311422 single base substitution G C intron_variant BRCA-US 15 86311422 86311422 single base substitution G C synonymous_variant L540L 1620C>G BRCA-US 15 86311723 86311723 single base substitution A C intron_variant BRCA-US 15 86311723 86311723 single base substitution A C missense_variant V440G 1319T>G BRCA-US 15 86311929 86311929 single base substitution C T intron_variant BRCA-US 15 86311929 86311929 single base substitution C T synonymous_variant A371A 1113G>A BRCA-US 15 86311940 86311940 single base substitution A T intron_variant BRCA-US 15 86311940 86311940 single base substitution A T missense_variant W368R 1102T>A BRCA-US 15 86312361 86312361 single base substitution G C intron_variant BRCA-US 15 86312361 86312361 single base substitution G C synonymous_variant V227V 681C>G BTCA-JP 15 86311952 86311952 single base substitution C T intron_variant BTCA-JP 15 86311952 86311952 single base substitution C T missense_variant V364I 1090G>A BTCA-JP 15 86312008 86312008 single base substitution G A intron_variant BTCA-JP 15 86312008 86312008 single base substitution G A missense_variant T345M 1034C>T BTCA-JP 15 86312955 86312955 single base substitution C T intron_variant BTCA-JP 15 86312955 86312955 single base substitution C T synonymous_variant P29P 87G>A CLLE-ES 15 86314429 86314429 single base substitution C T intron_variant CLLE-ES 15 86339894 86339894 single base substitution C T upstream_gene_variant COAD-US 15 86311413 86311413 single base substitution G A intron_variant COAD-US 15 86311413 86311413 single base substitution G A synonymous_variant V543V 1629C>T COAD-US 15 86311513 86311513 single base substitution C T intron_variant COAD-US 15 86311513 86311513 single base substitution C T missense_variant R510H 1529G>A COAD-US 15 86311588 86311588 single base substitution G A intron_variant COAD-US 15 86311588 86311588 single base substitution G A missense_variant T485I 1454C>T COAD-US 15 86311695 86311695 single base substitution G A intron_variant COAD-US 15 86311695 86311695 single base substitution G A synonymous_variant F449F 1347C>T COAD-US 15 86311930 86311930 single base substitution G A intron_variant COAD-US 15 86311930 86311930 single base substitution G A missense_variant A371V 1112C>T COAD-US 15 86312074 86312074 single base substitution T C intron_variant COAD-US 15 86312074 86312074 single base substitution T C missense_variant K323R 968A>G COAD-US 15 86312255 86312255 single base substitution T A intron_variant COAD-US 15 86312255 86312255 single base substitution T A stop_gained K263* 787A>T COAD-US 15 86312482 86312482 single base substitution C T intron_variant COAD-US 15 86312482 86312482 single base substitution C T missense_variant S187N 560G>A COAD-US 15 86312616 86312616 single base substitution C A intron_variant COAD-US 15 86312616 86312616 single base substitution C A missense_variant K142N 426G>T COAD-US 15 86312670 86312670 single base substitution G A intron_variant COAD-US 15 86312670 86312670 single base substitution G A synonymous_variant G124G 372C>T COAD-US 15 86312809 86312809 single base substitution C T intron_variant COAD-US 15 86312809 86312809 single base substitution C T missense_variant G78D 233G>A COAD-US 15 86312901 86312901 single base substitution G A intron_variant COAD-US 15 86312901 86312901 single base substitution G A synonymous_variant D47D 141C>T COCA-CN 15 86306160 86306160 single base substitution G A intron_variant COCA-CN 15 86311522 86311522 single base substitution G A intron_variant COCA-CN 15 86311522 86311522 single base substitution G A missense_variant S507L 1520C>T COCA-CN 15 86313015 86313015 single base substitution G A intron_variant COCA-CN 15 86313015 86313015 single base substitution G A synonymous_variant R9R 27C>T COCA-CN 15 86313810 86313810 single base substitution C T intron_variant ESAD-UK 15 86299837 86299837 single base substitution C T downstream_gene_variant ESAD-UK 15 86303030 86303030 single base substitution A C 3_prime_UTR_variant ESAD-UK 15 86303030 86303030 single base substitution A C downstream_gene_variant ESAD-UK 15 86306713 86306713 single base substitution C T intron_variant ESAD-UK 15 86307916 86307916 single base substitution G C intron_variant ESAD-UK 15 86309306 86309306 single base substitution G C intron_variant ESAD-UK 15 86312053 86312053 single base substitution C T intron_variant ESAD-UK 15 86312053 86312053 single base substitution C T missense_variant R330Q 989G>A ESAD-UK 15 86312204 86312204 single base substitution C A intron_variant ESAD-UK 15 86312204 86312204 single base substitution C A missense_variant D280Y 838G>T ESAD-UK 15 86315339 86315339 single base substitution G A intron_variant ESAD-UK 15 86317654 86317654 single base substitution A G intron_variant ESAD-UK 15 86318051 86318051 deletion of <=200bp C - intron_variant ESAD-UK 15 86318652 86318652 single base substitution C T intron_variant ESAD-UK 15 86320247 86320247 single base substitution T G intron_variant ESAD-UK 15 86322096 86322096 single base substitution A C intron_variant ESAD-UK 15 86322820 86322820 single base substitution G A intron_variant ESAD-UK 15 86326285 86326285 single base substitution G A intron_variant ESAD-UK 15 86329841 86329841 single base substitution G A intron_variant ESAD-UK 15 86332672 86332672 single base substitution C T intron_variant ESAD-UK 15 86335295 86335295 single base substitution T C intron_variant ESAD-UK 15 86335658 86335658 single base substitution C T intron_variant ESAD-UK 15 86341431 86341431 single base substitution G A upstream_gene_variant ESAD-UK 15 86341694 86341694 single base substitution G A upstream_gene_variant ESAD-UK 15 86343099 86343099 single base substitution A G upstream_gene_variant ESCA-CN 15 86312923 86312923 single base substitution C T intron_variant ESCA-CN 15 86312923 86312923 single base substitution C T missense_variant R40H 119G>A KIRC-US 15 86311567 86311567 single base substitution C A intron_variant KIRC-US 15 86311567 86311567 single base substitution C A missense_variant S492I 1475G>T KIRC-US 15 86312584 86312584 single base substitution A G intron_variant KIRC-US 15 86312584 86312584 single base substitution A G missense_variant M153T 458T>C LAML-KR 15 86312156 86312156 single base substitution T A intron_variant LAML-KR 15 86312156 86312156 single base substitution T A missense_variant T296S 886A>T LAML-KR 15 86319218 86319218 single base substitution C T intron_variant LGG-US 15 86311637 86311637 single base substitution C T intron_variant LGG-US 15 86311637 86311637 single base substitution C T missense_variant E469K 1405G>A LGG-US 15 86312652 86312652 single base substitution G A intron_variant LGG-US 15 86312652 86312652 single base substitution G A synonymous_variant H130H 390C>T LIAD-FR 15 86312352 86312352 single base substitution G A intron_variant LIAD-FR 15 86312352 86312352 single base substitution G A synonymous_variant P230P 690C>T LICA-CN 15 86311521 86311521 single base substitution C A intron_variant LICA-CN 15 86311521 86311521 single base substitution C A synonymous_variant S507S 1521G>T LICA-FR 15 86309060 86309060 insertion of <=200bp - AA intron_variant LICA-FR 15 86309380 86309380 single base substitution T A intron_variant LICA-FR 15 86311546 86311546 single base substitution C T intron_variant LICA-FR 15 86311546 86311546 single base substitution C T missense_variant G499D 1496G>A LICA-FR 15 86311749 86311749 single base substitution C T intron_variant LICA-FR 15 86311749 86311749 single base substitution C T synonymous_variant R431R 1293G>A LICA-FR 15 86312088 86312088 single base substitution C T intron_variant LICA-FR 15 86312088 86312088 single base substitution C T synonymous_variant K318K 954G>A LICA-FR 15 86312473 86312473 single base substitution T C intron_variant LICA-FR 15 86312473 86312473 single base substitution T C missense_variant K190R 569A>G LICA-FR 15 86337367 86337367 single base substitution A C intron_variant LICA-FR 15 86341178 86341178 single base substitution A G upstream_gene_variant LINC-JP 15 86312758 86312758 single base substitution G A intron_variant LINC-JP 15 86312758 86312758 single base substitution G A missense_variant P95L 284C>T LINC-JP 15 86316120 86316120 single base substitution C A intron_variant LINC-JP 15 86322657 86322657 single base substitution G A intron_variant LINC-JP 15 86328796 86328796 deletion of <=200bp T - intron_variant LINC-JP 15 86328908 86328908 single base substitution C T intron_variant LINC-JP 15 86334135 86334135 deletion of <=200bp A - intron_variant LINC-JP 15 86341693 86341693 single base substitution C T upstream_gene_variant LINC-JP 15 86342237 86342237 single base substitution T C upstream_gene_variant LIRI-JP 15 86300306 86300306 single base substitution G A downstream_gene_variant LIRI-JP 15 86301685 86301685 single base substitution C G downstream_gene_variant LIRI-JP 15 86302346 86302346 single base substitution T A downstream_gene_variant LIRI-JP 15 86302527 86302527 single base substitution C A downstream_gene_variant LIRI-JP 15 86305948 86305948 single base substitution G A intron_variant LIRI-JP 15 86307712 86307712 single base substitution C T intron_variant LIRI-JP 15 86311384 86311384 single base substitution T G intron_variant LIRI-JP 15 86311384 86311384 single base substitution T G missense_variant K553T 1658A>C LIRI-JP 15 86314150 86314150 single base substitution C A intron_variant LIRI-JP 15 86315462 86315462 single base substitution G A intron_variant LIRI-JP 15 86318017 86318017 single base substitution T C intron_variant LIRI-JP 15 86318418 86318418 single base substitution T C intron_variant LIRI-JP 15 86320034 86320034 single base substitution T C intron_variant LIRI-JP 15 86321123 86321123 single base substitution A C intron_variant LIRI-JP 15 86321169 86321169 single base substitution A G intron_variant LIRI-JP 15 86323319 86323319 single base substitution G C intron_variant LIRI-JP 15 86324519 86324519 single base substitution A T intron_variant LIRI-JP 15 86324598 86324598 single base substitution G T intron_variant LIRI-JP 15 86325550 86325550 single base substitution C T intron_variant LIRI-JP 15 86330507 86330507 single base substitution G A intron_variant LIRI-JP 15 86330989 86330989 single base substitution T C intron_variant LIRI-JP 15 86334682 86334682 single base substitution C A intron_variant LIRI-JP 15 86335737 86335737 single base substitution G C intron_variant LIRI-JP 15 86336323 86336323 single base substitution C G intron_variant LIRI-JP 15 86337436 86337436 single base substitution T A intron_variant LIRI-JP 15 86338666 86338666 single base substitution T A upstream_gene_variant LIRI-JP 15 86340151 86340151 single base substitution T C upstream_gene_variant LUSC-KR 15 86302735 86302735 single base substitution A T 3_prime_UTR_variant LUSC-KR 15 86302735 86302735 single base substitution A T downstream_gene_variant LUSC-KR 15 86302735 86302735 single base substitution A T intron_variant LUSC-KR 15 86314415 86314415 single base substitution T A intron_variant LUSC-KR 15 86318126 86318126 single base substitution G C intron_variant LUSC-KR 15 86318126 86318126 single base substitution G T intron_variant LUSC-KR 15 86320296 86320296 single base substitution C G intron_variant LUSC-KR 15 86340993 86340993 single base substitution A G upstream_gene_variant LUSC-US 15 86311564 86311564 single base substitution T C intron_variant LUSC-US 15 86311564 86311564 single base substitution T C missense_variant Q493R 1478A>G LUSC-US 15 86312069 86312069 single base substitution C A intron_variant LUSC-US 15 86312069 86312069 single base substitution C A missense_variant D325Y 973G>T MALY-DE 15 86302709 86302709 single base substitution G A 3_prime_UTR_variant MALY-DE 15 86302709 86302709 single base substitution G A downstream_gene_variant MALY-DE 15 86308998 86308998 single base substitution G C intron_variant MALY-DE 15 86319716 86319719 deletion of <=200bp TCAA - intron_variant MALY-DE 15 86324125 86324125 single base substitution C T intron_variant MALY-DE 15 86328478 86328478 single base substitution C G intron_variant MALY-DE 15 86329804 86329804 single base substitution C A intron_variant MALY-DE 15 86334396 86334396 single base substitution A G intron_variant MALY-DE 15 86337486 86337486 single base substitution C T intron_variant MELA-AU 15 86298109 86298109 single base substitution T G downstream_gene_variant MELA-AU 15 86299533 86299533 single base substitution G A downstream_gene_variant MELA-AU 15 86299597 86299597 single base substitution C T downstream_gene_variant MELA-AU 15 86299877 86299877 single base substitution C T downstream_gene_variant MELA-AU 15 86300336 86300336 single base substitution G A downstream_gene_variant MELA-AU 15 86300928 86300928 single base substitution G A downstream_gene_variant MELA-AU 15 86301561 86301561 single base substitution C T downstream_gene_variant MELA-AU 15 86301604 86301604 single base substitution C T downstream_gene_variant MELA-AU 15 86302268 86302268 single base substitution G A downstream_gene_variant MELA-AU 15 86302337 86302337 single base substitution G A downstream_gene_variant MELA-AU 15 86302448 86302448 single base substitution G A downstream_gene_variant MELA-AU 15 86302771 86302771 single base substitution G A 3_prime_UTR_variant MELA-AU 15 86302771 86302771 single base substitution G A downstream_gene_variant MELA-AU 15 86302771 86302771 single base substitution G A intron_variant MELA-AU 15 86304092 86304092 single base substitution C T 3_prime_UTR_variant MELA-AU 15 86304092 86304092 single base substitution C T exon_variant MELA-AU 15 86304301 86304301 single base substitution C T intron_variant MELA-AU 15 86304648 86304648 single base substitution A T intron_variant MELA-AU 15 86304662 86304662 single base substitution G A intron_variant MELA-AU 15 86304773 86304773 single base substitution C A intron_variant MELA-AU 15 86305329 86305329 single base substitution A C intron_variant MELA-AU 15 86305606 86305606 single base substitution G A intron_variant MELA-AU 15 86305967 86305967 single base substitution G A intron_variant MELA-AU 15 86306293 86306293 single base substitution G A intron_variant MELA-AU 15 86306889 86306889 single base substitution G C intron_variant MELA-AU 15 86307210 86307210 single base substitution G A intron_variant MELA-AU 15 86307491 86307491 single base substitution G A intron_variant MELA-AU 15 86308284 86308284 single base substitution G A intron_variant MELA-AU 15 86308514 86308514 single base substitution G A intron_variant MELA-AU 15 86308832 86308832 single base substitution G T intron_variant MELA-AU 15 86309298 86309298 single base substitution C T intron_variant MELA-AU 15 86309974 86309974 single base substitution G A intron_variant MELA-AU 15 86310820 86310820 single base substitution C T intron_variant MELA-AU 15 86311177 86311177 single base substitution G A intron_variant MELA-AU 15 86311213 86311214 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 15 86311214 86311214 single base substitution G A intron_variant MELA-AU 15 86311305 86311305 single base substitution G A intron_variant MELA-AU 15 86311305 86311305 single base substitution G A synonymous_variant A579A 1737C>T MELA-AU 15 86311819 86311819 single base substitution G A intron_variant MELA-AU 15 86311819 86311819 single base substitution G A missense_variant S408F 1223C>T MELA-AU 15 86311910 86311911 multiple base substitution (>=2bp and <=200bp) GG TA intron_variant MELA-AU 15 86311910 86311911 multiple base substitution (>=2bp and <=200bp) GG TA missense_variant AR377AS MELA-AU 15 86312045 86312045 single base substitution A C intron_variant MELA-AU 15 86312045 86312045 single base substitution A C missense_variant F333V 997T>G MELA-AU 15 86312049 86312049 single base substitution C T intron_variant MELA-AU 15 86312049 86312049 single base substitution C T synonymous_variant K331K 993G>A MELA-AU 15 86312057 86312057 single base substitution G A intron_variant MELA-AU 15 86312057 86312057 single base substitution G A missense_variant P329S 985C>T MELA-AU 15 86312415 86312415 single base substitution C T intron_variant MELA-AU 15 86312415 86312415 single base substitution C T synonymous_variant V209V 627G>A MELA-AU 15 86312651 86312651 single base substitution C T intron_variant MELA-AU 15 86312651 86312651 single base substitution C T missense_variant D131N 391G>A MELA-AU 15 86313325 86313325 single base substitution G A intron_variant MELA-AU 15 86313374 86313374 single base substitution G A intron_variant MELA-AU 15 86313409 86313409 single base substitution A T intron_variant MELA-AU 15 86314395 86314395 single base substitution G A intron_variant MELA-AU 15 86314540 86314540 single base substitution G A intron_variant MELA-AU 15 86314772 86314772 single base substitution G C intron_variant MELA-AU 15 86315131 86315131 single base substitution G A intron_variant MELA-AU 15 86316499 86316499 single base substitution G A intron_variant MELA-AU 15 86317119 86317119 single base substitution C T intron_variant MELA-AU 15 86317839 86317839 single base substitution G A intron_variant MELA-AU 15 86317966 86317966 single base substitution G A intron_variant MELA-AU 15 86318094 86318094 single base substitution G A intron_variant MELA-AU 15 86318131 86318131 single base substitution G A intron_variant MELA-AU 15 86318404 86318404 single base substitution G A intron_variant MELA-AU 15 86319762 86319762 single base substitution C T intron_variant MELA-AU 15 86319880 86319880 single base substitution G A intron_variant MELA-AU 15 86320160 86320160 single base substitution A T intron_variant MELA-AU 15 86320645 86320645 single base substitution G A intron_variant MELA-AU 15 86321116 86321116 single base substitution G A intron_variant MELA-AU 15 86321241 86321241 single base substitution G T intron_variant MELA-AU 15 86321462 86321462 single base substitution T A intron_variant MELA-AU 15 86322151 86322151 single base substitution G A intron_variant MELA-AU 15 86322332 86322332 single base substitution G A intron_variant MELA-AU 15 86322751 86322751 single base substitution G A intron_variant MELA-AU 15 86323488 86323488 single base substitution G A intron_variant MELA-AU 15 86324857 86324857 single base substitution G A intron_variant MELA-AU 15 86325106 86325106 single base substitution G A intron_variant MELA-AU 15 86325200 86325200 single base substitution C T intron_variant MELA-AU 15 86325783 86325783 single base substitution C T intron_variant MELA-AU 15 86326476 86326476 single base substitution G C intron_variant MELA-AU 15 86327208 86327208 single base substitution G A intron_variant MELA-AU 15 86327312 86327312 single base substitution C T intron_variant MELA-AU 15 86327373 86327373 single base substitution C G intron_variant MELA-AU 15 86327982 86327982 single base substitution G T intron_variant MELA-AU 15 86330167 86330167 single base substitution T A intron_variant MELA-AU 15 86330255 86330255 single base substitution C T intron_variant MELA-AU 15 86330572 86330572 single base substitution G A intron_variant MELA-AU 15 86330822 86330822 single base substitution G A intron_variant MELA-AU 15 86331051 86331051 single base substitution G A intron_variant MELA-AU 15 86331138 86331138 single base substitution G A intron_variant MELA-AU 15 86331275 86331275 single base substitution G A intron_variant MELA-AU 15 86331574 86331574 single base substitution G A intron_variant MELA-AU 15 86331583 86331583 single base substitution C T intron_variant MELA-AU 15 86331752 86331752 single base substitution G A intron_variant MELA-AU 15 86332601 86332601 single base substitution G A intron_variant MELA-AU 15 86333490 86333490 single base substitution C T intron_variant MELA-AU 15 86333857 86333858 multiple base substitution (>=2bp and <=200bp) GA AT intron_variant MELA-AU 15 86334020 86334020 single base substitution G A intron_variant MELA-AU 15 86334021 86334021 single base substitution A T intron_variant MELA-AU 15 86334050 86334050 single base substitution G A intron_variant MELA-AU 15 86334209 86334209 single base substitution G A intron_variant MELA-AU 15 86334762 86334762 single base substitution C T intron_variant MELA-AU 15 86335154 86335154 single base substitution T A intron_variant MELA-AU 15 86335750 86335751 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 15 86337098 86337099 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 15 86338311 86338311 single base substitution G A upstream_gene_variant MELA-AU 15 86338395 86338395 single base substitution A G upstream_gene_variant MELA-AU 15 86338688 86338688 single base substitution C T upstream_gene_variant MELA-AU 15 86338726 86338726 single base substitution C T upstream_gene_variant MELA-AU 15 86338822 86338822 single base substitution C T upstream_gene_variant MELA-AU 15 86339853 86339853 single base substitution G A upstream_gene_variant MELA-AU 15 86339966 86339967 multiple base substitution (>=2bp and <=200bp) GG AA upstream_gene_variant MELA-AU 15 86340084 86340084 single base substitution G A upstream_gene_variant MELA-AU 15 86340316 86340316 single base substitution C T upstream_gene_variant MELA-AU 15 86340450 86340450 single base substitution G A upstream_gene_variant MELA-AU 15 86340585 86340585 single base substitution G A upstream_gene_variant MELA-AU 15 86340809 86340809 single base substitution C T upstream_gene_variant MELA-AU 15 86340846 86340846 single base substitution C T upstream_gene_variant MELA-AU 15 86340870 86340870 single base substitution C T upstream_gene_variant MELA-AU 15 86341192 86341192 single base substitution C T upstream_gene_variant MELA-AU 15 86341329 86341329 single base substitution G A upstream_gene_variant MELA-AU 15 86341514 86341514 single base substitution C T upstream_gene_variant MELA-AU 15 86341595 86341595 single base substitution C T upstream_gene_variant MELA-AU 15 86341722 86341722 single base substitution G A upstream_gene_variant MELA-AU 15 86341927 86341927 single base substitution C T upstream_gene_variant MELA-AU 15 86342038 86342039 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 15 86342050 86342050 single base substitution G A upstream_gene_variant MELA-AU 15 86342213 86342213 single base substitution G A upstream_gene_variant MELA-AU 15 86342235 86342235 single base substitution C T upstream_gene_variant MELA-AU 15 86342295 86342295 single base substitution C T upstream_gene_variant MELA-AU 15 86342462 86342462 single base substitution C T upstream_gene_variant MELA-AU 15 86342641 86342641 single base substitution C T upstream_gene_variant MELA-AU 15 86342703 86342703 single base substitution A G upstream_gene_variant MELA-AU 15 86342789 86342789 single base substitution G A upstream_gene_variant MELA-AU 15 86342793 86342793 single base substitution C T upstream_gene_variant MELA-AU 15 86342857 86342857 single base substitution G A upstream_gene_variant MELA-AU 15 86342873 86342873 single base substitution G A upstream_gene_variant MELA-AU 15 86343084 86343084 single base substitution C T upstream_gene_variant MELA-AU 15 86343255 86343255 single base substitution G A upstream_gene_variant ORCA-IN 15 86308866 86308867 deletion of <=200bp AG - intron_variant ORCA-IN 15 86328324 86328325 deletion of <=200bp TC - intron_variant OV-AU 15 86305310 86305310 single base substitution A G intron_variant OV-AU 15 86318157 86318157 single base substitution G A intron_variant OV-AU 15 86321077 86321077 single base substitution G C intron_variant OV-AU 15 86322133 86322133 single base substitution G A intron_variant OV-AU 15 86323037 86323037 single base substitution A G intron_variant OV-AU 15 86332505 86332505 single base substitution A C intron_variant OV-AU 15 86333722 86333722 single base substitution A C intron_variant OV-US 15 86311340 86311340 single base substitution T C intron_variant OV-US 15 86311340 86311340 single base substitution T C missense_variant I568V 1702A>G PACA-AU 15 86301427 86301427 insertion of <=200bp - GGGAGAGAGG downstream_gene_variant PACA-AU 15 86306273 86306273 single base substitution G A intron_variant PACA-AU 15 86324249 86324249 single base substitution G C intron_variant PACA-AU 15 86325551 86325551 single base substitution G A intron_variant PACA-AU 15 86329192 86329192 insertion of <=200bp - C intron_variant PACA-AU 15 86331556 86331556 single base substitution C G intron_variant PACA-AU 15 86336564 86336564 single base substitution C T intron_variant PACA-AU 15 86338747 86338747 single base substitution A G upstream_gene_variant PACA-AU 15 86340911 86340911 single base substitution C A upstream_gene_variant PACA-AU 15 86341869 86341869 single base substitution G A upstream_gene_variant PACA-CA 15 86301640 86301640 single base substitution C T downstream_gene_variant PACA-CA 15 86305318 86305318 single base substitution A C intron_variant PACA-CA 15 86306260 86306260 single base substitution C A intron_variant PACA-CA 15 86306691 86306691 single base substitution C T intron_variant PACA-CA 15 86311730 86311730 single base substitution C T intron_variant PACA-CA 15 86311730 86311730 single base substitution C T missense_variant A438T 1312G>A PACA-CA 15 86320657 86320657 single base substitution G C intron_variant PACA-CA 15 86321596 86321596 single base substitution A C intron_variant PACA-CA 15 86327211 86327211 single base substitution T A intron_variant PACA-CA 15 86332116 86332116 single base substitution G A intron_variant PACA-CA 15 86333701 86333701 single base substitution C T intron_variant PACA-CA 15 86334187 86334187 single base substitution C G intron_variant PACA-CA 15 86337525 86337525 single base substitution C T intron_variant PACA-CA 15 86337599 86337599 single base substitution C T intron_variant PACA-CA 15 86339036 86339036 single base substitution T G upstream_gene_variant PACA-CA 15 86340687 86340687 single base substitution G A upstream_gene_variant PAEN-AU 15 86298433 86298433 single base substitution G T downstream_gene_variant PAEN-AU 15 86301410 86301410 single base substitution T G downstream_gene_variant PBCA-DE 15 86312171 86312171 single base substitution G A intron_variant PBCA-DE 15 86312171 86312171 single base substitution G A missense_variant R291C 871C>T PBCA-DE 15 86313912 86313912 single base substitution C T intron_variant PBCA-DE 15 86340826 86340826 single base substitution C T upstream_gene_variant PRAD-CA 15 86300813 86300813 single base substitution C T downstream_gene_variant PRAD-CA 15 86314449 86314449 single base substitution G A intron_variant PRAD-CA 15 86338083 86338083 single base substitution C G 5_prime_UTR_variant PRAD-CA 15 86338083 86338083 single base substitution C G exon_variant PRAD-CA 15 86342517 86342517 single base substitution G A upstream_gene_variant PRAD-UK 15 86303300 86303300 single base substitution G A 3_prime_UTR_variant PRAD-UK 15 86303300 86303300 single base substitution G A downstream_gene_variant PRAD-UK 15 86305053 86305053 single base substitution C T intron_variant PRAD-UK 15 86309768 86309768 single base substitution G A intron_variant PRAD-UK 15 86321125 86321125 single base substitution C G intron_variant PRAD-UK 15 86331226 86331226 single base substitution G A intron_variant RECA-EU 15 86302096 86302096 single base substitution A G downstream_gene_variant RECA-EU 15 86309327 86309327 single base substitution A T intron_variant RECA-EU 15 86322839 86322839 single base substitution C G intron_variant RECA-EU 15 86329015 86329015 single base substitution C G intron_variant SKCA-BR 15 86298073 86298073 single base substitution A T downstream_gene_variant SKCA-BR 15 86298650 86298650 single base substitution G A downstream_gene_variant SKCA-BR 15 86300645 86300645 single base substitution T G downstream_gene_variant SKCA-BR 15 86301058 86301058 single base substitution G A downstream_gene_variant SKCA-BR 15 86302926 86302926 single base substitution C G 3_prime_UTR_variant SKCA-BR 15 86302926 86302926 single base substitution C G downstream_gene_variant SKCA-BR 15 86307138 86307138 single base substitution G A intron_variant SKCA-BR 15 86308229 86308229 single base substitution G A intron_variant SKCA-BR 15 86314960 86314960 single base substitution G A intron_variant SKCA-BR 15 86316976 86316976 single base substitution G A intron_variant SKCA-BR 15 86317870 86317870 single base substitution A C intron_variant SKCA-BR 15 86317876 86317876 single base substitution T C intron_variant SKCA-BR 15 86318786 86318786 single base substitution G C intron_variant SKCA-BR 15 86320028 86320028 single base substitution T G intron_variant SKCA-BR 15 86320167 86320167 insertion of <=200bp - AT intron_variant SKCA-BR 15 86321907 86321907 single base substitution C T intron_variant SKCA-BR 15 86322276 86322277 deletion of <=200bp AT - intron_variant SKCA-BR 15 86323965 86323965 single base substitution G A intron_variant SKCA-BR 15 86326125 86326125 single base substitution T G intron_variant SKCA-BR 15 86328325 86328325 single base substitution C T intron_variant SKCA-BR 15 86331964 86331964 single base substitution G A intron_variant SKCA-BR 15 86335994 86335994 single base substitution G A intron_variant SKCA-BR 15 86336298 86336298 single base substitution G C intron_variant SKCA-BR 15 86338009 86338009 single base substitution T C 5_prime_UTR_variant SKCA-BR 15 86338009 86338009 single base substitution T C exon_variant SKCA-BR 15 86338152 86338152 single base substitution T C 5_prime_UTR_variant SKCA-BR 15 86338152 86338152 single base substitution T C upstream_gene_variant SKCA-BR 15 86339112 86339112 single base substitution T G upstream_gene_variant SKCA-BR 15 86339118 86339118 single base substitution T G upstream_gene_variant SKCA-BR 15 86340437 86340437 single base substitution C T upstream_gene_variant SKCA-BR 15 86341941 86341941 single base substitution G A upstream_gene_variant SKCA-BR 15 86342214 86342214 single base substitution G A upstream_gene_variant SKCA-BR 15 86342674 86342674 insertion of <=200bp - CAGAG upstream_gene_variant SKCM-US 15 86311557 86311557 single base substitution G A intron_variant SKCM-US 15 86311557 86311557 single base substitution G A synonymous_variant F495F 1485C>T SKCM-US 15 86311959 86311959 single base substitution G A intron_variant SKCM-US 15 86311959 86311959 single base substitution G A synonymous_variant Y361Y 1083C>T SKCM-US 15 86312345 86312345 single base substitution G A intron_variant SKCM-US 15 86312345 86312345 single base substitution G A missense_variant L233F 697C>T SKCM-US 15 86312415 86312415 single base substitution C T intron_variant SKCM-US 15 86312415 86312415 single base substitution C T synonymous_variant V209V 627G>A STAD-US 15 86311474 86311474 single base substitution T A intron_variant STAD-US 15 86311474 86311474 single base substitution T A missense_variant D523V 1568A>T STAD-US 15 86311599 86311599 single base substitution A G intron_variant STAD-US 15 86311599 86311599 single base substitution A G synonymous_variant P481P 1443T>C STAD-US 15 86311755 86311755 deletion of <=200bp G - frameshift_variant P429 STAD-US 15 86311755 86311755 deletion of <=200bp G - intron_variant STAD-US 15 86311780 86311780 single base substitution G A intron_variant STAD-US 15 86311780 86311780 single base substitution G A missense_variant A421V 1262C>T STAD-US 15 86311859 86311859 single base substitution C A intron_variant STAD-US 15 86311859 86311859 single base substitution C A stop_gained G395* 1183G>T STAD-US 15 86311917 86311917 single base substitution C T intron_variant STAD-US 15 86311917 86311917 single base substitution C T synonymous_variant L375L 1125G>A STAD-US 15 86312936 86312936 single base substitution G T intron_variant STAD-US 15 86312936 86312936 single base substitution G T missense_variant L36I 106C>A STAD-US 15 86312998 86312998 single base substitution G A intron_variant STAD-US 15 86312998 86312998 single base substitution G A missense_variant T15M 44C>T UCEC-US 15 86311486 86311486 single base substitution G A intron_variant UCEC-US 15 86311486 86311486 single base substitution G A missense_variant T519M 1556C>T UCEC-US 15 86311751 86311751 single base substitution G A intron_variant UCEC-US 15 86311751 86311751 single base substitution G A missense_variant R431W 1291C>T UCEC-US 15 86311930 86311930 single base substitution G A intron_variant UCEC-US 15 86311930 86311930 single base substitution G A missense_variant A371V 1112C>T UCEC-US 15 86312200 86312200 single base substitution C T intron_variant UCEC-US 15 86312200 86312200 single base substitution C T missense_variant G281D 842G>A UCEC-US 15 86312633 86312633 single base substitution C T intron_variant UCEC-US 15 86312633 86312633 single base substitution C T missense_variant A137T 409G>A UCEC-US 15 86312711 86312711 single base substitution C T intron_variant UCEC-US 15 86312711 86312711 single base substitution C T missense_variant A111T 331G>A UCEC-US 15 86312924 86312924 single base substitution G A intron_variant UCEC-US 15 86312924 86312924 single base substitution G A missense_variant R40C 118C>T

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand 021T COSM1731481 c.905delG p.G302fs*43 Deletion - Frameshift 15:85768906-85768906 - CHC1591T COSM4800442 c.569A>G p.K190R Substitution - Missense 15:85769242-85769242 - PTC-53C COSM4128516 c.773C>A p.A258E Substitution - Missense 15:85769038-85769038 - TCGA-AA-3662-01 COSM1375158 c.968A>G p.K323R Substitution - Missense 15:85768843-85768843 - TCGA-AZ-6598-01 COSM1375156 c.1529G>A p.R510H Substitution - Missense 15:85768282-85768282 - TCGA-AO-A03T-01 COSM434477 c.1113G>A p.A371A Substitution - coding silent 15:85768698-85768698 - ESO-409 COSM1255973 c.1762C>T p.P588S Substitution - Missense 15:85768049-85768049 - MOLT-4 COSM1678652 c.812G>A p.R271H Substitution - Missense 15:85768999-85768999 - SS6003311 COSM3665104 c.838G>T p.D280Y Substitution - Missense 15:85768973-85768973 - CHC892T COSM4960280 c.1496G>A p.G499D Substitution - Missense 15:85768315-85768315 - LUAD-RT-S01702 COSM379068 c.1644G>A p.G548G Substitution - coding silent 15:85768167-85768167 - SW48 COSM2014050 c.1083C>T p.Y361Y Substitution - coding silent 15:85768728-85768728 - ESCC_62 COSM5633051 c.529G>C p.E177Q Substitution - Missense 15:85769282-85769282 - T3202 COSM4696502 c.905G>A p.G302D Substitution - Missense 15:85768906-85768906 - NB07C COSM1236454 c.1184G>A p.G395E Substitution - Missense 15:85768627-85768627 - TCGA-F1-6874-01 COSM4057593 c.1443T>C p.P481P Substitution - coding silent 15:85768368-85768368 - T613 COSM4696501 c.1034C>T p.T345M Substitution - Missense 15:85768777-85768777 - CHOL11 COSM1743662 c.1283C>T p.A428V Substitution - Missense 15:85768528-85768528 - CHC892T COSM4794318 c.1293G>A p.R431R Substitution - coding silent 15:85768518-85768518 - 2492700 COSM5599793 c.1053G>A p.E351E Substitution - coding silent 15:85768758-85768758 - Pat_41_B COSM5849992 c.469G>A p.D157N Substitution - Missense 15:85769342-85769342 - TCGA-HU-A4GT-01 COSM4057592 c.1568A>T p.D523V Substitution - Missense 15:85768243-85768243 - TCGA-G2-A2EL-01 COSM1301518 c.1212G>A p.P404P Substitution - coding silent 15:85768599-85768599 - BD72T COSM5513117 c.1090G>A p.V364I Substitution - Missense 15:85768721-85768721 - SS6003312 COSM3665104 c.838G>T p.D280Y Substitution - Missense 15:85768973-85768973 - TCGA-BR-4368-01 COSM4057594 c.1262C>T p.A421V Substitution - Missense 15:85768549-85768549 - YUKAT COSM5384023 c.23C>T p.T8I Substitution - Missense 15:85769788-85769788 - BD57T COSM5510754 c.87G>A p.P29P Substitution - coding silent 15:85769724-85769724 - 587278 COSM1212628 c.1348G>A p.G450R Substitution - Missense 15:85768463-85768463 - CSCC-16-T COSM4462581 c.1251C>T p.Y417Y Substitution - coding silent 15:85768560-85768560 - TCGA-A6-5665-01 COSM966080 c.1112C>T p.A371V Substitution - Missense 15:85768699-85768699 - CHEWS008 COSM4578583 c.209A>G p.Y70C Substitution - Missense 15:85769602-85769602 - YUKAT COSM5384022 c.1007C>T p.S336L Substitution - Missense 15:85768804-85768804 - Pat_76_A COSM4057594 c.1262C>T p.A421V Substitution - Missense 15:85768549-85768549 - Au2 COSM5599793 c.1053G>A p.E351E Substitution - coding silent 15:85768758-85768758 - TCGA-D8-A1JA-01 COSM3816964 c.681C>G p.V227V Substitution - coding silent 15:85769130-85769130 - TCGA-AZ-6598-01 COSM1375155 c.1629C>T p.V543V Substitution - coding silent 15:85768182-85768182 - 2492702 COSM5599793 c.1053G>A p.E351E Substitution - coding silent 15:85768758-85768758 - CHC1591T COSM4800442 c.569A>G p.K190R Substitution - Missense 15:85769242-85769242 - TCGA-AZ-6598-01 COSM1375164 c.141C>T p.D47D Substitution - coding silent 15:85769670-85769670 - T3202 COSM4696503 c.53T>C p.M18T Substitution - Missense 15:85769758-85769758 - TCGA-60-2724-01 COSM701481 c.1478A>G p.Q493R Substitution - Missense 15:85768333-85768333 - SC_9029 COSM5555715 c.1630G>A p.G544R Substitution - Missense 15:85768181-85768181 - TCGA-EE-A3AD-06 COSM3504909 c.1485C>T p.F495F Substitution - coding silent 15:85768326-85768326 - TCGA-G4-6626-01 COSM1375159 c.787A>T p.K263* Substitution - Nonsense 15:85769024-85769024 - 01-P8014 COSM4578582 c.1620C>T p.L540L Substitution - coding silent 15:85768191-85768191 - TCGA-AA-3715-01 COSM269466 c.218C>T p.A73V Substitution - Missense 15:85769593-85769593 - PCSI_0083_Pa_X COSM2014041 c.1312G>A p.A438T Substitution - Missense 15:85768499-85768499 - CSCC-44-T COSM4515118 c.999C>T p.F333F Substitution - coding silent 15:85768812-85768812 - PT35 COSM5913684 c.283C>T p.P95S Substitution - Missense 15:85769528-85769528 - CLL005 COSM1290447 c.504C>G p.S168S Substitution - coding silent 15:85769307-85769307 - TCGA-EE-A2MF-06 COSM4893210 c.627G>A p.V209V Substitution - coding silent 15:85769184-85769184 - 8034291 COSM3387121 c.139G>A p.D47N Substitution - Missense 15:85769672-85769672 - ESCC_BICR_031T COSM2014085 c.119G>A p.R40H Substitution - Missense 15:85769692-85769692 - 1N34-VS-1T34 COSM4974684 c.1285C>T p.P429S Substitution - Missense 15:85768526-85768526 - CHC892T COSM4794318 c.1293G>A p.R431R Substitution - coding silent 15:85768518-85768518 - D01 COSM4254677 c.235C>T p.L79F Substitution - Missense 15:85769576-85769576 - CSCC-35-T COSM4514059 c.960C>T p.I320I Substitution - coding silent 15:85768851-85768851 - TCGA-CG-5726-01 COSM4057598 c.44C>T p.T15M Substitution - Missense 15:85769767-85769767 - 2492701 COSM5599793 c.1053G>A p.E351E Substitution - coding silent 15:85768758-85768758 - ATL089 COSM5705976 c.640A>G p.I214V Substitution - Missense 15:85769171-85769171 - TCGA-AX-A063-01 COSM966078 c.1556C>T p.T519M Substitution - Missense 15:85768255-85768255 - ESCC_139 COSM2014043 c.1300G>A p.V434I Substitution - Missense 15:85768511-85768511 - CHC205T COSM3765829 c.361C>T p.L121L Substitution - coding silent 15:85769450-85769450 - T3062 COSM4696500 c.1304G>A p.S435N Substitution - Missense 15:85768507-85768507 - TCGA-AC-A3W6-01 COSM3816963 c.1620C>G p.L540L Substitution - coding silent 15:85768191-85768191 - TCGA-D3-A51T-06 COSM3504910 c.697C>T p.L233F Substitution - Missense 15:85769114-85769114 - pfg019T COSM1640371 c.1609G>A p.G537S Substitution - Missense 15:85768202-85768202 - YULONE COSM966083 c.118C>T p.R40C Substitution - Missense 15:85769693-85769693 - 02-P170 COSM4578582 c.1620C>T p.L540L Substitution - coding silent 15:85768191-85768191 - pfg181T COSM4758425 c.1217C>T p.S406L Substitution - Missense 15:85768594-85768594 - sysucc-880T COSM5462489 c.27C>T p.R9R Substitution - coding silent 15:85769784-85769784 - PD13302a COSM5783448 c.101C>T p.A34V Substitution - Missense 15:85769710-85769710 - CSCC-29-T COSM4462058 c.1230C>T p.S410S Substitution - coding silent 15:85768581-85768581 - HT115 COSM2014039 c.1366C>A p.R456R Substitution - coding silent 15:85768445-85768445 - CAKI-1 COSM1678653 c.394G>A p.V132M Substitution - Missense 15:85769417-85769417 - TCGA-AA-3672-01 COSM266792 c.331G>A p.A111T Substitution - Missense 15:85769480-85769480 - TCGA-21-1071-01 COSM701480 c.973G>T p.D325Y Substitution - Missense 15:85768838-85768838 - WA30 COSM236772 c.1003G>A p.A335T Substitution - Missense 15:85768808-85768808 - TCGA-D1-A167-01 COSM966080 c.1112C>T p.A371V Substitution - Missense 15:85768699-85768699 - HX24T COSM3706785 c.284C>T p.P95L Substitution - Missense 15:85769527-85769527 - HN_62854 COSM124005 c.43A>G p.T15A Substitution - Missense 15:85769768-85769768 - TCGA-D1-A177-01 COSM966081 c.842G>A p.G281D Substitution - Missense 15:85768969-85768969 - CN-AML-CR-4-Dx COSM5427024 c.886A>T p.T296S Substitution - Missense 15:85768925-85768925 - ATL012 COSM5705975 c.694C>T p.L232F Substitution - Missense 15:85769117-85769117 - ESCC_46 COSM5630505 c.421G>C p.E141Q Substitution - Missense 15:85769390-85769390 - 40M COSM5585623 c.645C>T p.L215L Substitution - coding silent 15:85769166-85769166 - MB_Exm564 COSM215621 c.871C>T p.R291C Substitution - Missense 15:85768940-85768940 - TCGA-CG-4437-01 COSM4057596 c.1125G>A p.L375L Substitution - coding silent 15:85768686-85768686 - Pat_76_B COSM4057594 c.1262C>T p.A421V Substitution - Missense 15:85768549-85768549 - 2553_T COSM3957021 c.163C>T p.R55C Substitution - Missense 15:85769648-85769648 - TCGA-G9-6342-01 COSM3672126 c.408C>A p.A136A Substitution - coding silent 15:85769403-85769403 - GBM_IV-19 COSM4966992 c.362T>C p.L121P Substitution - Missense 15:85769449-85769449 - CSCC-55-T COSM4513346 c.934C>T p.Q312* Substitution - Nonsense 15:85768877-85768877 - sysucc-834T COSM5485772 c.1520C>T p.S507L Substitution - Missense 15:85768291-85768291 - TCGA-13-1505-01 COSM71361 c.115C>T p.L39F Substitution - Missense 15:85769696-85769696 - pfg122T COSM2014069 c.625G>A p.V209M Substitution - Missense 15:85769186-85769186 - TCGA-AP-A056-01 COSM266792 c.331G>A p.A111T Substitution - Missense 15:85769480-85769480 - TCGA-B5-A11E-01 COSM966082 c.409G>A p.A137T Substitution - Missense 15:85769402-85769402 - HCC101T COSM5813275 c.1521G>T p.S507S Substitution - coding silent 15:85768290-85768290 - cSCCP1 COSM135682 c.1255C>T p.P419S Substitution - Missense 15:85768556-85768556 - PCSI_0083_Pa_P_526 COSM2014041 c.1312G>A p.A438T Substitution - Missense 15:85768499-85768499 - TCGA-CJ-4913-01 COSM471194 c.1475G>T p.S492I Substitution - Missense 15:85768336-85768336 - MD-051 COSM302504 c.1057G>T p.G353W Substitution - Missense 15:85768754-85768754 - RW2982 COSM4649549 c.1118C>G p.P373R Substitution - Missense 15:85768693-85768693 - CSCC-55-T COSM4468470 c.1545C>T p.T515T Substitution - coding silent 15:85768266-85768266 - TCGA-13-0924-01 COSM75166 c.1702A>G p.I568V Substitution - Missense 15:85768109-85768109 - CSCC-49-T COSM4467960 c.1518C>T p.A506A Substitution - coding silent 15:85768293-85768293 - CSCC-29-T COSM4527828 c.1493G>A p.G498E Substitution - Missense 15:85768318-85768318 - CSCC-35-T COSM4564687 c.1365_1366CC>TT p.R456W Substitution - Missense 15:85768445-85768446 - HN_62539 COSM128344 c.705C>T p.S235S Substitution - coding silent 15:85769106-85769106 - TCGA-AX-A0J1-01 COSM966079 c.1291C>T p.R431W Substitution - Missense 15:85768520-85768520 - TCGA-B0-4818-01 COSM471196 c.458T>C p.M153T Substitution - Missense 15:85769353-85769353 - SM2-1 COSM3727592 c.1594C>A p.H532N Substitution - Missense 15:85768217-85768217 - EGC15 COSM5054562 c.956A>T p.E319V Substitution - Missense 15:85768855-85768855 - CHC892T COSM4798288 c.954G>A p.K318K Substitution - coding silent 15:85768857-85768857 - 90827 COSM329465 c.868C>T p.P290S Substitution - Missense 15:85768943-85768943 - 2492703 COSM5599793 c.1053G>A p.E351E Substitution - coding silent 15:85768758-85768758 - 7285 COSM5614300 c.1643G>C p.G548A Substitution - Missense 15:85768168-85768168 - RK090_C01 COSM3701025 c.1658A>C p.K553T Substitution - Missense 15:85768153-85768153 - LS411 COSM2014087 c.45G>A p.T15T Substitution - coding silent 15:85769766-85769766 - 18 COSM5745267 c.1516G>A p.A506T Substitution - Missense 15:85768295-85768295 - LC_S12 COSM1189096 c.535G>T p.V179L Substitution - Missense 15:85769276-85769276 - TCGA-B5-A0JV-01 COSM966077 c.1647C>A p.T549T Substitution - coding silent 15:85768164-85768164 - TCGA-AM-5820-01 COSM3754542 c.1347C>T p.F449F Substitution - coding silent 15:85768464-85768464 - S02289 COSM5685976 c.745G>C p.A249P Substitution - Missense 15:85769066-85769066 - TCGA-BR-6454-01 COSM4057595 c.1183G>T p.G395* Substitution - Nonsense 15:85768628-85768628 - TCGA-HT-7608-01 COSM3969318 c.390C>T p.H130H Substitution - coding silent 15:85769421-85769421 - 6 COSM1237226 c.1275G>A p.M425I Substitution - Missense 15:85768536-85768536 - TCGA-EB-A4P0-01 COSM2014050 c.1083C>T p.Y361Y Substitution - coding silent 15:85768728-85768728 - LUAD-E00934 COSM393261 c.1595A>T p.H532L Substitution - Missense 15:85768216-85768216 - TCGA-AA-3713-01 COSM1375160 c.560G>A p.S187N Substitution - Missense 15:85769251-85769251 - PD7219a COSM5775140 c.1148C>A p.S383* Substitution - Nonsense 15:85768663-85768663 - PTC-7C COSM3754542 c.1347C>T p.F449F Substitution - coding silent 15:85768464-85768464 - TCGA-F4-6570-01 COSM1375157 c.1454C>T p.T485I Substitution - Missense 15:85768357-85768357 - SNU-C4 COSM4652653 c.667G>A p.E223K Substitution - Missense 15:85769144-85769144 - CHC892T COSM4960280 c.1496G>A p.G499D Substitution - Missense 15:85768315-85768315 - TCGA-AA-3710-01 COSM293549 c.434delT p.F145fs*8 Deletion - Frameshift 15:85769377-85769377 - TCGA-GI-A2C8-01 COSM1478440 c.1319T>G p.V440G Substitution - Missense 15:85768492-85768492 - TCGA-AZ-6598-01 COSM1375163 c.233G>A p.G78D Substitution - Missense 15:85769578-85769578 - TCGA-B5-A11W-01 COSM966083 c.118C>T p.R40C Substitution - Missense 15:85769693-85769693 - YUKLAB COSM1708504 c.1559G>A p.R520Q Substitution - Missense 15:85768252-85768252 - TCGA-HU-A4GN-01 COSM4057597 c.106C>A p.L36I Substitution - Missense 15:85769705-85769705 - LUAD-E01317 COSM403689 c.273C>T p.D91D Substitution - coding silent 15:85769538-85769538 - TCGA-A1-A0SH-01 COSM434478 c.1102T>A p.W368R Substitution - Missense 15:85768709-85768709 - TCGA-AA-3510-01 COSM1375161 c.426G>T p.K142N Substitution - Missense 15:85769385-85769385 - TCGA-AA-3712-01 COSM1375162 c.372C>T p.G124G Substitution - coding silent 15:85769439-85769439 - BD57T COSM4696501 c.1034C>T p.T345M Substitution - Missense 15:85768777-85768777 - CHC892T COSM4798288 c.954G>A p.K318K Substitution - coding silent 15:85768857-85768857 - YUGATOR COSM5384021 c.1522G>A p.A508T Substitution - Missense 15:85768289-85768289 - TCGA-HT-7857-01 COSM3969317 c.1405G>A p.E469K Substitution - Missense 15:85768406-85768406 - pfg127T COSM4758426 c.701G>A p.R234H Substitution - Missense 15:85769110-85769110 - 1 COSM4166586 c.1084G>A p.D362N Substitution - Missense 15:85768727-85768727 - ESO-049 COSM1255972 c.1051G>A p.E351K Substitution - Missense 15:85768760-85768760 - LIM2551 COSM4643934 c.693G>A p.E231E Substitution - coding silent 15:85769118-85769118 - CHC605T COSM3667766 c.690C>T p.P230P Substitution - coding silent 15:85769121-85769121 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.498371 15q25.3

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Missense p.V440G c.1319T>G 15 86311723 BRCA A G Missense p.M153T c.458T>C 15 86312584 RCCC A G Synonymous p.P481P c.1443T>C 15 86311599 STAD - A IntronicInsertion . c.1767+2712dupT 15 86308563 CM A T Missense p.W368R c.1102T>A 15 86311940 BRCA C A Missense p.D325Y c.973G>T 15 86312069 LUSC C A Missense p.R12L c.35G>T 15 86313007 LUAD C A Missense p.S492I c.1475G>T 15 86311567 RCCC C A Nonsense p.E260* c.778G>T 15 86312264 HNSC C A Nonsense p.G395* c.1183G>T 15 86311859 STAD C A Synonymous p.V393V c.1179G>T 15 86311863 CM C G Missense p.G548A c.1643G>C 15 86311399 NSCLC C T IntronicSNV . c.1-1388G>A 15 86314429 CLL C T Missense p.E253K c.757G>A 15 86312285 HNSC C T Missense p.G281D c.842G>A 15 86312200 UCEC C T Missense p.G395E c.1184G>A 15 86311858 NB C T Missense p.G537S c.1609G>A 15 86311433 STAD C T Missense p.R12Q c.35G>A 15 86313007 STAD C T Missense p.S252N c.755G>A 15 86312287 RCCC C T Synonymous p.A371A c.1113G>A 15 86311929 BRCA C T Synonymous p.L33L c.99G>A 15 86312943 LUAD C T Synonymous p.L375L c.1125G>A 15 86311917 STAD C T Synonymous p.P404P c.1212G>A 15 86311830 BLCA C T Synonymous p.V209V c.627G>A 15 86312415 CM G A IntronicSNV . c.1-699C>T 15 86313740 CM G A Missense p.A135V c.404C>T 15 86312638 LUAD G A Missense p.A421V c.1262C>T 15 86311780 STAD G A Missense p.H6Y c.16C>T 15 86313026 CM G A Missense p.L39F c.115C>T 15 86312927 OV G A Missense p.P588S c.1762C>T 15 86311280 ESCA G A Missense p.R291C c.871C>T 15 86312171 MB G A Missense p.R40C c.118C>T 15 86312924 UCEC G A Missense p.T15M c.44C>T 15 86312998 STAD G A Missense p.T519M c.1556C>T 15 86311486 HNSC G A Missense p.T519M c.1556C>T 15 86311486 UCEC G A Synonymous p.F139F c.417C>T 15 86312625 CM G A Synonymous p.F495F c.1485C>T 15 86311557 CM G A Synonymous p.H130H c.390C>T 15 86312652 LGG G A Synonymous p.I276I c.828C>T 15 86312214 CM G A Synonymous p.I454I c.1362C>T 15 86311680 CM G A Synonymous p.S235S c.705C>T 15 86312337 HNSC G A Synonymous p.V462V c.1386C>T 15 86311656 BRCA G C Synonymous p.S168S c.504C>G 15 86312538 CLL GG AA Missense p.S27F c.80_81delinsTT 15 86312961 CM G T Missense p.A437D c.1310C>A 15 86311732 LUAD G T Missense p.H94N c.280C>A 15 86312762 HNSC G T Synonymous p.G294G c.882C>A 15 86312160 LUAD T A Missense p.I496F c.1486A>T 15 86311556 HNSC T C Missense p.I568V c.1702A>G 15 86311340 OV T C Missense p.Q493R c.1478A>G 15 86311564 LUSC T C Missense p.T15A c.43A>G 15 86312999 HNSC