PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SOCS3 MAP3K7 16543409 innatedb,biogrid exp GP GP G G G GP G G GP G G GP GP G G G GP G GP G GP G G G G G GP GP G SOCS3 RBMX 21988832 biogrid,intact exp P P P P P P P P P P P P P P P P P P P SOCS3 APP 21832049 innatedb,biogrid exp G GP G G GP GP G G GP G G G G G G GP GP G GP G GP G G G GP G G GP G SOCS3 TRDN 25814554 biogrid,intact exp P P P G P P P P P GP GP P SOCS3 NFKB1 21451109 biogrid exp GP G G G GP G G G GP G G G GP G G GP G G G G GP G GP G GP G G GP G SOCS3 RPL7A 21988832 biogrid,intact exp P P P P P P P P P P P SOCS3 SIGLEC7 17138568 innatedb,biogrid exp G GP G G P GP P GP GP GP G G GP P P G GP P GP G GP P G SOCS3 TES 21988832 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 BIK 21988832 biogrid,intact exp P P P P P P P GP P P P G GP P GP GP P SOCS3 KIAA1958 25416956 biogrid,intact exp GP GP G P GP G P P G GP GP GP G GP GP GP GP G P G GP GP GP GP GP G SOCS3 CXCR4 12163560 hprd,biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 HIVEP1 21988832 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP P G GP G GP GP GP G GP GP G SOCS3 PIN1 16169070 hprd,biogrid,i2d,mint,intact exp G GP G G GP GP G G GP G G G G G G G GP G P G P G G G G G GP GP G SOCS3 PDPK1 21900206 biogrid,mint,intact exp GP GP G G GP GP G G GP G GP G GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 PPP3CB 11970967 hprd exp GP G G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 PKM 24606918 intact exp GP GP G G GP GP G G GP G GP GP GP G G GP GP G GP G GP G GP G GP G GP GP G SOCS3 MAPK6 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 RASA1 11331873 hprd,biogrid,mint,intact exp GP G G G GP GP G G G G G G G G G G GP G G G GP G G G G G GP G G SOCS3 ELAVL1 23686487 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 CD33 17008544 innatedb exp G GP P SOCS3 AR 24728074 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G GP G SOCS3 NFKBIA 21451109 biogrid exp G GP G G GP GP G GP GP G G G GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 DAB1 17974915 biogrid exp G G GP G GP G G G G G GP GP G G G GP GP G NME4 SOCS3 21988832 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 YWHAQ 25814554 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 MAPK11 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP G G P GP GP GP G GP G GP GP P G GP GP G SOCS3 TNFSF10 21308719 biogrid exp GP GP G G G GP G G GP G GP G GP G G GP GP GP GP G GP G GP G GP G GP P G SOCS3 CUEDC2 22084247 biogrid exp G G G G GP GP G G G G GP G GP G G GP GP G G G G G G G GP G G G G SOCS3 GFRA1 21988832 biogrid,intact exp G G G P G G GP GP G GP GP G G G GP G G GP G P G G GP GP G GP GP G SOCS3 TFR2 21988832 biogrid,intact exp G G G G G G GP G G SOCS3 SNAI1 25203322 intact exp GP GP G GP P P P P P GP P P P P GP P GP P P P SOCS3 TXNDC11 21988832 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 TBK1 25939384 biogrid exp GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 RNF31 21988832 biogrid,intact exp P P G G GP GP P P G GP GP GP GP GP P GP G GP P GP GP G P GP SOCS3 REL 21451109 biogrid exp GP G G G GP GP G G GP G GP G GP G G GP GP GP GP G P G GP G GP G GP GP G SOCS3 ETV6 11314018 biogrid exp GP G G G GP GP G GP GP G G G GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 ACADVL 22093833 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 MET 24728074 intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 TCEB1 12783885,22084247,15601820,10051596,17135358, 25402006, 23023127 innatedb,hprd,biogrid,intact exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 EGFR 24658140,16273093,25402006,12070153, 25402006, 23023127 hprd,biogrid,i2d,intact exp, ortho, pred GP GP G GP G G GP G GP GP G G G GP GP G G G GP G G GP GP G GP GP G SOCS3 JAK1 16459330,10707961,10373548, 25402006 innatedb,hprd,biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 LEPR 11018044,21239736, 25402006 hprd,biogrid exp, ortho, pred GP GP G G GP G G GP G G GP G GP G G GP G G G G GP G GP GP GP G GP G SOCS3 MAP1S 19027008, 25402006 biogrid,mint,intact exp, ortho, pred GP G G G G G G GP GP G GP G GP G G GP G GP GP G GP G GP G GP G GP GP G SOCS3 CUL5 15601820,17135358, 25402006 innatedb,biogrid,intact exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 EPOR 12027890,10882725, 25402006, 21836163 hprd,biogrid,mint,intact exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 BCL10 15213237, 25402006 hprd exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 CSF1R 12133942, 23023127 hprd,biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 JAK2 15514089,24354892,11314018,10421843,10882725,22342841,19543316,9344848, 25402006, 23023127, 21836163 hprd,biogrid,mint,intact exp, ortho, pred G GP G G GP GP G GP GP G GP P GP G G P GP GP P P G GP G GP G GP GP SOCS2 SOCS3 16199887, 25402006, 23023127, 21836163 innatedb,hprd,biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 IL6ST 10777583,12403768,10946280, 25402006, 21836163 hprd,biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 INSR 15514089,12560330,11071852, 25402006, 23023127, 21836163 hprd,biogrid exp, ortho, pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 CSNK1E 15070676, 25402006 hprd exp, ortho, pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 TFDP1 18687693, 25402006 innatedb,biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 PTPN11 17138568,10777583,12403768, 25402006 hprd,biogrid exp, ortho, pred GP GP G G G GP G G GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 RNF7 15601820, 25402006 innatedb,biogrid,intact exp, ortho, pred GP GP G G GP GP G G GP G GP GP G G G GP GP G GP G GP G G G GP G GP GP G SOCS3 IRS1 15514089,12228220, 25402006, 23023127, 21836163 hprd,biogrid exp, pred GP GP G P GP G G GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP P G SOCS3 AXL 12470648, 23023127 innatedb exp, pred GP G G G G GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 KIT 24728074, 25402006 intact exp, pred G G G G GP GP G G G G G GP G G G GP GP G G G G G G G G G G SOCS3 MAP3K5 16407264, 25402006 biogrid exp, pred G GP G G GP GP G G GP G GP G GP G G G GP GP GP G G G G G G G GP GP G SOCS3 IL2RB 10373548, 25402006 innatedb,hprd,biogrid exp, pred G G G G GP G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 MAPK8IP1 18055217, 23023127 biogrid exp, pred P P G P GP G P P G P P P P GP P G P P P P P GP SOCS3 RELA 21451109, 23023127 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 IL12RB2 14559241, 25402006, 21836163 biogrid,mint,intact exp, pred P P P P P P P P P P P P GP G P G P P SOCS3 GHR 10585430, 25402006, 21836163 hprd,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 PRLR 11713228, 25402006, 21836163 hprd,biogrid exp, pred G G G G G G G G G G G G G G G G G G G SOCS3 YES1 25416956, 25402006 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 GAB1 24728074, 25402006 intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 TRAF6 16543409, 23023127 innatedb,biogrid exp, pred GP GP G G GP G G GP GP G GP GP GP G G GP G GP G G GP G GP G GP G GP GP G SOCS3 IGF1R 11071852, 25402006, 23023127, 21836163 hprd,biogrid,i2d exp, pred GP GP G G G G G GP GP G GP GP GP G G GP G G GP G GP G GP G GP G GP GP G SOCS3 ABL1 22787435, 25402006, 23023127 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 FGFR3 16410555, 23023127 biogrid exp, pred G P G P GP GP G G GP G GP GP G G GP G GP G G GP SOCS3 SH2D2A 25814554, 23023127 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 TFDP3 18687693, 25402006 innatedb exp, pred G SOCS3 IRS2 15514089, 25402006, 23023127, 21836163 hprd,biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 NONO 18952062, 21836163 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 PTK2 25416956,16007195,18031698, 25402006 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 PTK2B 18507841,9344848, 25402006 biogrid exp, pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G P G G G GP G GP GP G SOCS3 VHL 21685897, 25402006 biogrid exp, pred G G G G G G G G G G GP GP GP G G G G G P G G G GP G G G G GP G SOCS3 TCEB2 16007195,15601820,10051596,17135358, 25402006, 21836163 innatedb,hprd,biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 CSF3R 12133942, 25402006 innatedb,hprd exp, pred G G G G GP GP G GP G G G G GP G G G GP G G GP G G G G G G GP G SOCS3 JAK3 10373548,15385932, 25402006, 23023127 innatedb,hprd,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 LCK 21234523, 23023127 biogrid exp, pred G G GP G G G G G G G G G G G G G G SOCS3 PTK6 22547065, 25402006, 23023127 biogrid exp, pred GP GP G GP GP P GP G P P GP G GP GP P P G P GP GP GP G GP P SOCS3 NOD2 ortho P G GP P P P GP P P P P P P P G P SOCS3 IDO1 ortho GP GP G G G GP P G GP G G G GP G G G GP G G G GP GP G SOCS3 SMAD3 25402006 ortho, pred GP GP G G G GP G G G G G G GP G G G GP G GP G GP G G G G G G G G SOCS3 STAT3 25402006, 23023127, 21836163 ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 PIM1 25402006 ortho, pred G GP G G GP GP G G GP G GP GP G G G GP GP G G G G G G GP GP G GP GP G SOCS3 NCK1 25402006, 23023127 ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 LMO4 25402006 ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 CRKL 25402006, 23023127 ortho, pred GP G G G GP GP G G GP G G G GP G G GP GP G GP G GP G G G GP G GP G G SOCS3 CAV1 23023127 pred GP G G G G GP G GP GP G GP GP GP G G G GP GP G G GP G G G G G G G G SOCS3 PACSIN3 23023127 pred GP GP GP G GP P P GP P G G GP GP GP GP GP G GP GP GP GP P G SOCS3 BTBD7 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 ZBTB7A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 PLCG1 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 NACC2 23023127 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP G GP G GP G GP GP G SOCS3 RASGEF1B 16082366 pred P P P P G P P P P P P P P SOCS3 RFWD3 23023127 pred G G G G G G G G G G G G G G G G G G SOCS3 ANGPT2 23023127 pred G P P G GP P P P G G P P G P GP GP P SOCS3 NACC1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 MYOF 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 SOS1 16082366 pred GP G G G GP G G GP GP G GP G GP G G GP G G GP G GP G GP GP GP G GP G G SOCS3 ZBTB25 23023127 pred GP G G P G P P G P P G G GP G P G P GP G SOCS3 CLNK 25402006 pred P P P P P P P P GP P GP P GP P P SOCS3 SDC1 23023127 pred GP GP G G GP G G G GP G GP G G G G GP G G GP G GP G GP G GP G GP GP G SOCS3 TXNDC5 23023127 pred P P P P P P P SOCS3 INPP5D 25402006, 23023127 pred G GP G G GP GP G GP G G GP G G G G G GP GP G G G G GP GP G G G G G SOCS3 CALM1, CALM2, CALM3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 BIRC3 23023127 pred GP G GP G G GP P GP G G G GP G GP P G GP GP G GP GP SOCS3 E2F6 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G SOCS3 ESX1 23023127 pred G GP SOCS3 IGFBP4 23023127 pred GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 AKT2 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 IL21R 25402006 pred P P P P P P P P G P P P P P P P G P P SOCS3 ASAP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 AKAP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 GRB2 25402006, 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 DNAJA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 GPX1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G G G GP G GP G GP GP G SOCS3 SQSTM1 23023127 pred GP GP G G GP G G G GP G GP GP GP G G GP G GP GP G GP G GP GP GP G GP GP G SOCS3 FER 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 CDKN1A 23023127 pred GP GP G G GP G G G GP G G G GP G G GP G G G G GP G G G GP G G GP G SOCS3 IGFBP7 23023127 pred G G G G G G G G G G GP G G G G G G G GP G G G G G G G G GP G SOCS3 CKLF 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 FN1 23023127 pred G G G G GP GP G GP GP G GP GP G G G G GP GP G G GP G G G G G G G G SOCS3 STAT5B 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G G G GP G GP G GP G GP GP G SOCS3 EGLN1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 ENPP1 23023127 pred GP G G G GP G G G G GP GP G G G G GP G GP G G G G G G G GP GP G SOCS3 ITGB8 23023127 pred GP GP G P GP G GP GP G GP G G GP GP G GP G GP G GP GP GP GP G G SOCS3 PLG 23023127 pred P P G G P P P P SOCS3 HIF1A 23023127 pred GP GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP G GP G GP G GP GP G SOCS3 Fos39347_1 25402006 pred SOCS3 NRP1 23023127 pred GP GP G P GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP P G SOCS3 EPHA3 23023127 pred GP P P P G GP GP P GP P G G GP P P GP G P P GP GP P SOCS3 GRB14 25402006, 23023127 pred P GP P P G GP GP GP G P G P P G GP GP P P GP P GP SOCS3 PLD2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 RASGRP1 16082366 pred G G G G G G G G G G G G G G G G G G G SOCS3 TYK2 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 KALRN 23023127 pred P P G P GP G P P G P P P P GP P P P P P G P P SOCS3 ZBTB18 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 ARHGAP4 23023127 pred G G G GP G GP G G G G G G SOCS3 A2M 23023127 pred G G G G G GP G G GP G G GP G G G G GP G G G GP G G G G G G G G SOCS3 F3 23023127 pred GP GP G P GP G G G G GP P GP G G GP GP G GP G GP G G G GP G GP GP G SOCS3 SH2D3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 SH2D1A 23023127 pred G G SOCS3 IL6 25402006 pred GP G G G GP G G G G G G G G G G G G G G G G G GP G G G G G G E2F3 SOCS3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 IRS4 25402006 pred GP GP G G G GP G GP GP G GP P P G G GP GP G GP G GP GP GP GP G GP GP G SOCS3 BTBD6 23023127 pred G G G G GP G G G GP G G G G G G GP G G G G G G G GP GP G G G G SOCS3 APOH 23023127 pred G GP GP P G G G G G G P SOCS3 RGL2 16082366 pred GP GP G G G GP G GP GP G GP GP G G G GP GP G GP G G G G GP GP G GP GP G SOCS3 KLHL26 23023127 pred GP P G P GP G P GP G GP P P G G GP GP P GP G P G GP GP GP GP GP G SOCS3 TNFRSF1A 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 CASP8 23023127 pred GP GP G GP P GP GP GP GP GP G G GP P GP P G GP G GP P GP G GP GP G SOCS3 GCM1 23023127 pred P P GP P SOCS3 KLHL18 23023127 pred G GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G G GP GP GP G GP GP G SOCS3 BACH1 23023127 pred GP GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 CEBPB 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 FYB 23023127 pred G G G GP G G G G G G G G G G G G G G G G G G SOCS3 DNMT3B 23023127 pred GP P G G GP GP G GP P GP GP GP G GP GP GP GP G GP GP GP GP G GP GP SOCS3 BTK 23023127 pred G G GP G G GP G G G G G SOCS3 APBA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 TSC2 23023127 pred G GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G G G GP G GP GP G SOCS3 ERBB3 25402006 pred GP GP G P GP G GP GP G GP GP GP G G GP GP P GP G GP G GP P GP GP GP G SOCS3 SRMS 25402006 pred P P P P P P P P P P P P P P P P P P P SOCS3 SOCS5 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 TNN 16082366 pred GP G G G G GP G G GP G P GP GP G G GP GP GP GP G P G GP GP G GP P G SOCS3 OSMR 25402006, 23023127 pred GP GP P G GP GP P P GP G G P P G GP GP G P P P P P G SOCS3 IHH 23023127 pred P P P P P GP P GP P GP P P P P G P GP GP GP P G SOCS3 STXBP4 23023127 pred P GP G GP P P P GP P P G P P GP GP G GP G P P GP P P G PLK4 SOCS3 23023127 pred P P G GP P P GP P P P P P P P P P P P GP GP SOCS3 JUNB 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 RIPK1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 KLHL1 23023127 pred P G P G P P G P P P P P SOCS3 PRKDC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 SPSB1 25402006 pred GP GP G G GP GP G GP G G GP GP GP G G G GP G GP G GP G G GP G GP GP G SOCS3 PLEK 23023127 pred G G G G GP GP G G G G G G GP G G G GP G G G G G G G G G G G G SOCS3 PLXNA3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 SOCS4 25402006, 23023127 pred GP GP G G GP GP G G GP G GP G GP G G GP GP G G G GP G GP GP GP G GP GP G SOCS3 MAPK8IP2 25402006, 23023127 pred G GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 GATA3 23023127 pred G GP G G G G G G GP G GP GP GP G G GP G G G G GP G G G GP G GP GP G SOCS3 BCAR3 25402006, 23023127, 16082366 pred GP GP G P GP G GP GP G GP GP GP G G GP GP G P G GP G GP GP GP G GP GP G SOCS3 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GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 KCNA5 23023127 pred P P P GP P G P P P P P P P P P P P P P SOCS3 S100A9 25402006 pred GP G G GP G G G G GP G G G G G G G G G G G G G SOCS3 ABI3 23023127 pred G G G G GP GP G GP GP G GP G GP G G GP GP G G G G G GP GP G G G SOCS3 VAV1 25402006, 23023127 pred GP GP G GP GP G P P G P GP GP G G GP GP G GP G GP G GP P P G GP GP G SOCS3 IL1B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 CSF2RA 21836163 pred GP P G GP P P P P P P P GP P P SOCS3 COPS6 25402006 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 PCDH12 23023127 pred GP GP G GP P G GP GP GP G GP G G GP P P G GP P GP GP G GP P G SOCS3 GLI3 23023127 pred GP GP G G GP GP G G GP G GP G GP G G GP GP GP G G GP G G G GP G GP GP G SOCS3 THBS1 23023127 pred GP GP G GP P G GP GP GP G GP G G GP GP GP GP G GP G GP P GP G GP P G SOCS3 STAT2 23023127 pred GP GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 NTRK3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 TGFB3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G G G GP GP GP G GP GP G SOCS3 CSF2RB 25402006, 21836163 pred GP P G G GP GP G GP GP G P GP GP G G GP GP GP GP G GP G GP GP GP G GP P G SOCS3 IPP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 PPBP 23023127 pred G GP P G P GP G SOCS3 FLNA 23023127 pred G G G G GP GP G G GP G GP GP GP G G G GP GP GP G GP G G G G G GP GP G SOCS3 LIMS1 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 ZBTB21 23023127 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP G G G GP G GP GP G SOCS3 KLHL3 23023127 pred G GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 NCF2 23023127 pred G G GP G G G GP G G G G G G G G G G G G SOCS3 ITSN2 23023127 pred G G G G G GP G G GP G GP GP G G G GP GP G GP G GP G G G GP G GP GP G SH2D7 SOCS3 23023127 pred P P P P P P P P SOCS3 GMCL1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 INHBB 23023127 pred GP GP G G GP GP G GP GP G P GP GP G G GP GP G GP G GP G GP GP GP GP GP G SOCS3 IL18 23023127 pred GP G GP G P GP P GP G GP P P P G GP G GP P SOCS3 SPINT1 23023127 pred GP P P P GP GP P GP G GP P P GP G GP G GP P GP GP P SOCS3 RASGEF1C 16082366 pred P P G P GP P P G P P P P GP P GP P P P P P GP SOCS3 MAP3K8 23023127 pred GP GP G GP P G GP GP GP GP GP G G P P GP P GP G P P GP G GP P G SOCS3 KBTBD4 23023127 pred GP GP GP G P G GP P P G GP GP G GP G P G GP G GP G P GP SOCS3 CITED1 23023127 pred G G G G G G G G SOCS3 VAV3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 KLHL21 23023127 pred GP GP G GP G GP GP G GP GP GP G G GP GP GP GP G P G G GP GP G GP GP G SOCS3 CBL 25402006 pred G GP G G GP GP G G GP G GP G GP G G G GP GP G G G G G G G G G GP G SOCS3 HSPG2 23023127 pred GP G P P G GP GP GP GP GP G G G GP GP GP G GP G G G G G GP GP G SOCS3 IL7R 25402006 pred GP G G GP GP G G GP G GP G GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 KLHL17 23023127 pred P G G G G G GP G P GP GP G G GP G G G G GP GP G GP GP G SOCS3 MYNN 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 CTTN 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 LRR1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 LYN 25402006, 23023127 pred GP G G G GP GP G G GP G G G GP G G GP GP G GP G GP G GP GP G GP G G SOCS3 ELK3 23023127 pred GP G G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G G GP G SOCS3 CISH 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 CCDC85B 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 ZBTB34 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 GNB2L1 25402006 pred P P P P P P P P P P P P P P P SOCS3 FYN 23023127 pred G GP G G GP GP G G GP G GP GP G G G G GP G G G G G G G G G G G G SOCS3 SH3BP2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 SASH3 23023127 pred GP G G G G GP G G GP G G G GP G G G GP G GP G GP G GP G G G GP GP G SOCS3 KLK6 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SOCS3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 ZBTB17 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 ZAP70 23023127 pred G G GP G G G G G G G G SOCS3 DOK2 23023127 pred G G G GP G G G G GP G G G G G G G G G G G G SOCS3 RIN1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 KLHL14 23023127 pred P P G GP P P P GP P P G P P P P P P P P G P P SOCS3 TNK2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 KHDRBS1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 SHB 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 KLHL40 23023127 pred GP G SOCS3 E2F5 25402006 pred G G G G G G G G G SOCS3 IL22RA2 21836163 pred P P P P P P P P P P P P GP P P P P P SOCS3 TGFB2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 RBX1 25402006 pred G G G G G GP G GP G G G G GP G G G GP G GP G GP G G G G G G GP G SOCS3 MMP19 23023127 pred G GP G GP P G G GP P G GP G G GP GP G GP G G G GP G GP P G SOCS3 SAMSN1 23023127 pred G GP G GP P G P GP P P GP G GP GP P P P GP G GP P SOCS3 ZBTB43 23023127 pred G GP G G G GP G G GP G G G GP G G G GP G GP G G G G G G G G GP G SOCS3 HOXD11 23023127 pred G G G G G SOCS3 ZBTB2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 TRIP10 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 HOXB7 23023127 pred GP GP G G P G P GP GP P GP G G GP GP P GP G GP G P P GP G GP GP G SOCS3 CD74 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 OSM 25402006, 16082366 pred P P G GP P P P GP P P P P P P P P P SOCS3 ITSN1 23023127 pred G GP G G G GP G GP GP G GP GP GP G G GP GP G G G GP G GP GP GP G GP GP G SOCS3 KLHL24 23023127 pred G G G G G GP G G G G G G G G G GP GP G GP G G G G G GP G G G G SOCS3 PTPRF 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP G GP GP G SOCS3 PIK3R3 25402006, 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP G GP G GP G GP G GP G GP GP G SOCS3 NCK2 25402006, 23023127 pred G GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 TP53 23023127 pred G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G SOCS3 KLF10 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 OBSCN 23023127 pred GP P P P GP GP GP P P G G P P P P G P G GP GP GP G GP P SOCS3 LRRC41 25402006 pred G G G G GP G G GP GP G GP G GP G G GP G G GP G GP G G GP GP G GP GP G SOCS3 ZBTB45 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 MLK4 23023127 pred P GP G G GP GP G GP G GP GP GP G G GP GP GP G GP G GP GP GP GP G SOCS3 EOMES 23023127 pred GP GP G GP GP G GP GP G GP G GP G G GP GP G GP G P G GP GP GP G GP GP G SOCS3 SNX9 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 STAT5A 25402006, 23023127 pred G GP G G GP G G G GP G GP GP GP G G G G GP GP G GP G G G G G G G G SOCS3 HSPB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP G G GP G GP GP G GP G GP GP GP G GP GP G SOCS3 KLHL6 23023127 pred GP P G GP P P GP P P GP G GP P P P P P GP G GP P SOCS3 BIRC6 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 IL4R 25402006 pred GP GP G G GP P G GP GP G GP G GP G G GP GP GP GP GP G GP P GP G GP GP G SOCS3 SORBS1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 IFNGR2 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 TRIM25 23023127 pred G GP G G GP GP G G GP G GP G GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 TNFRSF1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP GP G GP GP GP G GP P G ZBTB7C SOCS3 23023127 pred G GP G G P P P G G GP G G G GP GP SOCS3 ZBTB46 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP G GP P G SOCS3 BAIAP2 23023127 pred P P G G GP GP G GP P G GP GP GP G P GP GP GP G GP G P P P GP GP G SOCS3 KLHL28 23023127 pred G G G G G G G G G G GP GP G G G G G G GP G GP G G G G G G G G SOCS3 E2F2 25402006 pred GP GP G G G GP G G G P P G G G GP GP G P P G G G GP GP SOCS3 KBTBD3 23023127 pred G GP G G G G G P G G G G G G G G G G G GP G G G G G SOCS3 ADM 23023127 pred G GP G G GP GP G G G G GP G GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 PTPN6 25402006, 23023127 pred G G G G GP G G G G G G G GP G G G G G G G GP G G G G G G G G SOCS3 NR1H3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 ABTB2 23023127 pred GP GP G G GP GP G GP G G GP G GP G G GP GP G GP G GP G GP GP GP GP GP G SOCS3 LCP2 23023127 pred G G G GP G G G GP G G G G G G G G G SOCS3 SLA2 23023127 pred G G G G G G G G G G G G G G G G SOCS3 FGFR1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 ZAK 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP G GP G GP G GP GP G SOCS3 IRAK1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 KLHL34 23023127 pred P P P GP GP P P P P GP GP P P P P GP GP P P SOCS3 FLT1 23023127 pred G G G GP G GP GP G G G G G G G GP G G G GP G G GP G G G G G SOCS3 STAT6 23023127 pred GP GP G G GP GP G G GP G GP G GP G G GP GP GP G G GP G GP G GP G GP GP G SOCS3 CD276 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 KLK8 23023127 pred GP G G G G G G G G G GP G G G G G G G G G G G G G G G G G SOCS3 KLK14 23023127 pred P P P P P P P P P P P P P P P P P P P SOCS3 SKP1 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 PTPN1 25402006 pred GP GP G G GP G G G GP G GP GP GP G G GP G GP GP G GP G GP G GP G GP GP G SOCS3 GZF1 23023127 pred G GP G G G GP G GP GP G GP G GP G G GP GP GP GP G GP G G GP GP G G GP G SOCS3 IL10RA 25402006, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 PLAU 23023127 pred G G G GP P G G GP GP GP G G GP GP GP GP G GP G G G GP G GP GP G SOCS3 LRP1 23023127 pred G G G G G GP G G G G G GP GP G G G GP GP G G GP G G G G G G GP G SOCS3 CAMK2A 25402006 pred P P G GP G GP GP G GP P GP G G G GP GP G G GP G SOCS3 LY96 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 EREG 23023127 pred P G G P P P P P P P GP P P P P P P P SOCS3 ARHGEF19 23023127 pred G G G G G G G G G G G SOCS3 MMP2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 MAP3K9 23023127 pred P GP G P GP G GP G GP GP P G G GP GP P GP G GP G GP GP GP G GP GP G SOCS3 PRKCA 25402006, 23023127 pred G GP G G GP GP G GP GP G GP G G G G GP GP G GP G GP G G GP GP G GP GP G SOCS3 VASP 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 MYD88 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 MMP14 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G G GP GP G GP GP G SOCS3 CELSR1 23023127 pred G G G G G G G G G G G G SOCS3 LZTR1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 AKT1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 CD86 23023127 pred GP G G G GP GP G G P G GP GP G G GP GP G P G GP GP G P G GP P SOCS3 CFI 23023127 pred G G G G GP GP GP G G G G G G G G G G G G G G G G SOCS3 DGKD 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G SOCS3 KBTBD11 23023127 pred GP GP G G GP GP G P GP G GP GP GP G G GP GP P P G P G P GP GP G P P G SOCS3 MAP3K11 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 MAP1LC3B 25402006 pred G GP G G GP GP G GP GP G GP G G G G GP GP G G G G G G GP GP G GP GP G SOCS3 TNFAIP1 23023127 pred G G G G G G G G GP G GP G G G G GP G G GP G G G GP G GP G GP G G SOCS3 CTGF 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 KEAP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 ELANE 23023127 pred G GP G G SOCS3 CD40 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 ESR1 25402006 pred GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 ITK 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 PLCG2 25402006, 23023127 pred G GP G G GP GP G GP GP G GP G GP G G GP GP GP G G GP G G GP GP G GP GP G SOCS3 CTSC 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP G G GP G GP G GP G GP GP G SOCS3 IL1R1 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G SOCS3 FOSL1 23023127 pred GP G P P P G GP G P P G G P P SOCS3 FBXW8 23023127 pred P P P P P P P P P P P P P P P P P P SOCS3 COL3A1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 DAB2 23023127 pred G GP G G G G G G G G GP G GP G G G G G G G GP G G G G G G G G SOCS3 ERBB2 25402006, 23023127 pred GP G G G G G G G GP G GP G G G G GP G G G G GP G G G GP G G G G SOCS3 DNMBP 23023127 pred GP GP G G G GP G GP GP G G G GP G G G GP GP G G GP G G GP G G GP G G SOCS3 CCL2 23023127 pred GP GP G P GP G G GP GP GP GP G G GP GP GP GP G GP G P G GP G GP P G SOCS3 C1R 23023127 pred G G G G GP GP G G G G GP GP GP G G GP GP GP GP G G G G G GP G G GP G SOCS3 BMX 23023127 pred GP P G GP P G GP GP P P P G GP P GP P P GP P P SOCS3 NEDD9 23023127 pred GP GP G G GP GP G GP GP GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 ACR 23023127 pred G G G G G P P G G G G G G GP SOCS3 RGL1 16082366 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 IL2RG 25402006 pred G G G G GP GP G G GP G G G G G G G GP G G G G G G G G G GP G G BTBD17 SOCS3 23023127 pred P P P P P P SOCS3 BTBD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 INSRR 25402006 pred P P G GP P P P P P P P P P P P GP P P P SOCS3 INS 25402006 pred G GP G SOCS3 CCL5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS3 ABI1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 GAN 23023127 pred P P P P P P P P P P P P P P P P P P SOCS3 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P SOCS3 RAPGEF1 16082366 pred G GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP G G GP GP G GP GP G SOCS3 ACVRL1 23023127 pred G GP P P G GP GP G GP G G GP P G GP GP G G G GP G G P G SOCS3 HCK 23023127 pred GP G G G GP GP G G G G P GP GP G G GP GP GP GP G GP G GP GP GP G GP P G SOCS3 PLXND1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 SP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 PFN1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G SOCS3 KCTD14 23023127 pred P P P P P P P P P P P P SOCS3 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P08069 O14543 - 11071852 - X 2 O14543 P40337-3 affinity chromatography technology 21685897 physical association X 2 O14543 Q15369-2 affinity chromatography technology 17135358 physical association X 2 O14543 P41212 affinity chromatography technology 11314018 physical association X 2 O14543 P0CG48 affinity chromatography technology 22084247 physical association X 2 O14543 Q15369-2 affinity chromatography technology 22084247 physical association X 2 O14543 A0A024RBD2 affinity chromatography technology 16199887 physical association X 2 O14543 P40189-2 pull down 10777583 direct interaction X 2 O14543 P23458 affinity chromatography technology 10707961 physical association X 2 O14543 Q14289 affinity chromatography technology 18507841 physical association X 2 O14543 Q15369-2 pull down 12783885 direct interaction X 2 O14543 Q15369-2 affinity chromatography technology 12783885 physical association X 2 O14543 affinity chromatography technology 16410555 physical association X 2 O14543 affinity chromatography technology 21451109 physical association X 2 O14543 Q04206 affinity chromatography technology 21451109 physical association X 2 O14543 affinity chromatography technology 21451109 physical association X 2 O14543 Q04206 affinity chromatography technology 21451109 physical association X 2 O14543 P50591 affinity chromatography technology 21308719 physical association X 2 O14543 P23458 affinity chromatography technology 10373548 physical association X 2 O14543 P23458 enzymatic study 10373548 direct interaction X 2 O14543 P23458 pull down 10373548 direct interaction X 2 O14543 P14784 pull down 10373548 direct interaction X 2 O14543 affinity chromatography technology 15514089 physical association X 2 O14543 A0A024R499 affinity chromatography technology 15514089 physical association X 2 O14543 A0A024R499 affinity chromatography technology 15514089 physical association X 2 O14543 affinity chromatography technology 15514089 physical association X 2 O14543 affinity chromatography technology 16007195 physical association X 2 O14543 A0A024RDY4 affinity chromatography technology 18687693 physical association X 2 O14543 A0A024RDY4 two hybrid 18687693 direct interaction X 2 O14543 P05067-7 pull down 21832049 direct interaction X 2 O14543 Q9UBF6-2 affinity chromatography technology 15601820 physical association X 2 O14543 Q15369-2 affinity chromatography technology 15601820 physical association X 2 O14543 Q9D5V5 affinity chromatography technology 15601820 physical association X 2 O14543 Q9WTZ1 affinity chromatography technology 15601820 physical association X 2 O14543 P83940 affinity chromatography technology 15601820 physical association X 2 O14543 Q59FK4 affinity chromatography technology 22787435 physical association X 2 O14543 P0CG48 affinity chromatography technology 21963094 physical association X 2 O14543 O00746 two hybrid 21988832 direct interaction X 2 O14543 P15822 two hybrid 21988832 direct interaction X 2 O14543 P62424 two hybrid 21988832 direct interaction X 2 O14543 P56159-2 two hybrid 21988832 direct interaction X 2 O14543 two hybrid 21988832 direct interaction X 2 O14543 two hybrid 25416956 direct interaction X 2 O14543 P07947 two hybrid 25416956 direct interaction X 2 O14543 P16471-8 affinity chromatography technology 11713228 physical association X 2 O14543 affinity chromatography technology 12560330 physical association X 2 O14543 P40189-2 affinity chromatography technology 12403768 physical association X 2 O14543 P40189-2 pull down 12403768 direct interaction X 2 O14543 P19235 affinity chromatography technology 10882725 physical association X 2 O14543 P19235 affinity chromatography technology 10882725 physical association X 2 O14543 P19235 pull down 10882725 direct interaction X 2 O14543 P10912-2 pull down 10585430 direct interaction X 2 O14543 P07333 affinity chromatography technology 12133942 physical association X 2 O14543 P20936-4 pull down 11331873 direct interaction X 2 O14543 P20936-4 affinity chromatography technology 11331873 physical association X 2 O14543 P19235 pull down 12027890 direct interaction X 2 O14543 Q14289 two hybrid 9344848 direct interaction X 2 O14543 Q15233-2 affinity chromatography technology 18952062 physical association X 2 O14543 O43318-4 affinity chromatography technology 16543409 physical association X 2 O14543 Q9Y4K3 affinity chromatography technology 16543409 physical association X 2 O14543 P49748-3 two hybrid 22093833 direct interaction X 2 O14543 P49748-3 pull down 22093833 direct interaction X 2 O14543 affinity chromatography technology 18031698 physical association X 2 O14543 affinity chromatography technology 18031698 physical association X 2 Q9H467 O14543 affinity chromatography technology 22084247 physical association X 2 Q9H467 O14543 pull down 22084247 direct interaction X 2 Q9H467 O14543 affinity chromatography technology 22084247 physical association X 2 Q99683 O14543 affinity chromatography technology 16407264 physical association X 2 P62869 O14543 affinity chromatography technology 15601820 physical association X 2 O14543 O75553-6 affinity chromatography technology 17974915 physical association X 2 O14543 Q93034 affinity chromatography technology 17135358 physical association X 2 O14543 Q15370-2 affinity chromatography technology 17135358 physical association X 2 O14543 O60674 affinity chromatography technology 11314018 physical association X 2 O14543 O60674 affinity chromatography technology 19543316 physical association X 2 O14543 Q66K74 affinity chromatography technology 19027008 physical association X 2 O14543 Q66K74 affinity chromatography technology 19027008 physical association X 2 O14543 Q66K74 two hybrid 19027008 direct interaction X 2 O14543 Q99665 pull down 14559241 direct interaction X 2 O14543 Q99665 affinity chromatography technology 14559241 physical association X 2 O14543 Q06124-2 affinity chromatography technology 10777583 physical association X 2 O14543 Q9Y286-4 affinity chromatography technology 17138568 physical association X 2 O14543 Q06124-2 affinity chromatography technology 17138568 physical association X 2 O14543 Q04864 affinity chromatography technology 21451109 physical association X 2 O14543 P25963 affinity chromatography technology 21451109 physical association X 2 O14543 Q04864 affinity chromatography technology 21451109 physical association X 2 O14543 P25963 affinity chromatography technology 21451109 physical association X 2 O14543 A0A024R7M7 affinity chromatography technology 15385932 physical association X 2 O14543 O60674 pull down 22342841 direct interaction X 2 O14543 affinity chromatography technology 21234523 physical association X 2 O14543 O60674 affinity chromatography technology 15514089 physical association X 2 O14543 Q9Y4H2 affinity chromatography technology 15514089 physical association X 2 O14543 O60674 affinity chromatography technology 15514089 physical association X 2 O14543 Q9Y4H2 affinity chromatography technology 15514089 physical association X 2 O14543 Q15370-2 affinity chromatography technology 16007195 physical association X 2 O14543 Q93034 affinity chromatography technology 15601820 physical association X 2 O14543 Q15370-2 affinity chromatography technology 15601820 physical association X 2 O14543 P38159 two hybrid 21988832 direct interaction X 2 O14543 A0A024R4X6 two hybrid 21988832 direct interaction X 2 O14543 two hybrid 21988832 direct interaction X 2 O14543 Q6PKC3-2 two hybrid 21988832 direct interaction X 2 O14543 O60674 pull down 24354892 direct interaction X 2 O14543 Q8N8K9 two hybrid 25416956 direct interaction X 2 O14543 Q13882 affinity chromatography technology 22547065 physical association X 2 O14543 Q13882 affinity chromatography technology 22547065 physical association X 2 O14543 P00533 two hybrid 25402006 direct interaction X 2 O14543 Q13526 two hybrid 16169070 direct interaction X 2 O14543 P61073-2 affinity chromatography technology 12163560 physical association X 2 O14543 P48357-5 pull down 11018044 direct interaction X 2 O14543 Q06124-2 affinity chromatography technology 12403768 physical association X 2 O14543 Q06124-2 pull down 12403768 direct interaction X 2 O14543 O60674 affinity chromatography technology 10882725 physical association X 2 O14543 O60674 affinity chromatography technology 10882725 physical association X 2 O14543 O60674 two hybrid 10421843 direct interaction X 2 O14543 O60674 affinity chromatography technology 10421843 physical association X 2 O14543 O60674 pull down 10421843 direct interaction X 2 O14543 P00533 affinity chromatography technology 12070153 physical association X 2 O14543 O60674 two hybrid 9344848 direct interaction X 2 O14543 O60674 pull down 9344848 direct interaction X 2 O14543 P48357-5 affinity chromatography technology 21239736 physical association X 2 O14543 Q15759 two hybrid 21900206 direct interaction X 2 O14543 O15530-4 two hybrid 21900206 direct interaction X 2 O14543 Q16659 two hybrid 21900206 direct interaction X 2 Q96EP0 O14543 two hybrid 21988832 direct interaction X 2 P08069 O14543 pull down 11071852 direct interaction X 2 P08069 O14543 two hybrid 11071852 direct interaction X 2 P08069 O14543 affinity chromatography technology 11071852 physical association X 2 Q9UQF2 O14543 affinity chromatography technology 18055217 physical association X 2 O14543 anti tag coimmunoprecipitation 15677447 association C 5 O14543 P19235 in vitro 10882725,12027890 - X 2 O14543 P19235 in vivo 10882725,12027890 - X 2 O14543 Q99062-4 in vivo 12133942 - X 2 O14543 P20936 in vitro 11331873 - X 2 O14543 P20936 in vivo 11331873 - X 2 O14543 P14784 in vitro 10373548 - X 2 O14543 A0A024R499 in vitro 12228220 - X 2 O14543 A0A024R499 in vivo 12228220 - X 2 O14543 two hybrid 11071852,12560330 - X 2 O14543 in vitro 11071852,12560330 - X 2 O14543 P23458 in vivo 10707961 - X 2 O14543 P07333 in vivo 12133942 - X 2 O14543 P40189-2 in vivo 10946280,12403768 - X 2 O14543 P40189-2 in vitro 10946280,12403768 - X 2 O14543 Q15369-2 in vitro 10051596 - X 2 O14543 Q15369-2 in vivo 10051596 - X 2 O14543 in vivo 15514089 - X 2 O14543 P10912 in vivo 10585430 - X 2 O14543 P48357 in vivo 11018044 - X 2 O14543 P48357 in vitro 11018044 - X 2 O14543 O95999 in vivo 15213237 - X 2 O14543 P48357 in vitro 11018044 - X 2 O14543 P48357 in vivo 11018044 - X 2 O14543 Q99062-4 in vivo 12133942 - X 2 O14543 in vivo 15514089 - X 2 O14543 P23458 in vivo 10707961 - X 2 O14543 P14784 in vitro 10373548 - X 2 O14543 P40189-2 in vivo 10946280,12403768 - X 2 O14543 P40189-2 in vitro 10946280,12403768 - X 2 O14543 O95999 in vivo 15213237 - X 2 O14543 A0A024RBD2 in vitro 16199887 - X 2 O14543 P19235 in vitro 10882725,12027890 - X 2 O14543 P19235 in vivo 10882725,12027890 - X 2 O14543 P20936 in vivo 11331873 - X 2 O14543 P20936 in vitro 11331873 - X 2 O14543 A0A024R499 in vitro 12228220 - X 2 O14543 A0A024R499 in vivo 12228220 - X 2 O14543 two hybrid 11071852,12560330 - X 2 O14543 in vitro 11071852,12560330 - X 2 O14543 P07333 in vivo 12133942 - X 2 O14543 Q15369-2 in vivo 10051596 - X 2 O14543 Q15369-2 in vitro 10051596 - X 2 O14543 P10912 in vivo 10585430 - X 2 O14543 A0A024RBD2 in vitro 16199887 - X 2 O14543 P16298-3 in vitro 11970967 - X 2 O14543 P16298-3 in vivo 11970967 - X 2 O14543 P00533 in vitro 12070153 - X 2 O14543 P00533 in vivo 12070153 - X 2 O14543 O60674 in vitro 10421843,9344848 - X 2 O14543 O60674 in vivo 10421843,9344848 - X 2 O14543 O60674 two hybrid 10421843,9344848 - X 2 O14543 P16471 in vivo 11713228 - X 2 O14543 Q06124-2 in vitro 12403768 - X 2 O14543 A0A024R7M7 in vitro 10373548 - X 2 O14543 Q15370-2 in vitro 10051596 - X 2 O14543 Q15370-2 in vivo 10051596 - X 2 O14543 P49674 in vivo 15070676 - X 2 O14543 P49674 in vitro 15070676 - X 2 O14543 Q13526 two hybrid 16169070 - X 2 O14543 P16471 in vivo 11713228 - X 2 O14543 P16298-3 in vivo 11970967 - X 2 O14543 P16298-3 in vitro 11970967 - X 2 O14543 Q06124-2 in vitro 12403768 - X 2 O14543 Q13526 two hybrid 16169070 - X 2 O14543 A0A024R7M7 in vitro 10373548 - X 2 O14543 P49674 in vitro 15070676 - X 2 O14543 P49674 in vivo 15070676 - X 2 O14543 P00533 in vivo 12070153 - X 2 O14543 P00533 in vitro 12070153 - X 2 O14543 O60674 two hybrid 10421843,9344848 - X 2 O14543 O60674 in vitro 10421843,9344848 - X 2 O14543 O60674 in vivo 10421843,9344848 - X 2 O14543 Q15370-2 in vivo 10051596 - X 2 O14543 Q15370-2 in vitro 10051596 - X 2 P08069 O14543 in vitro 11071852 - X 2 P08069 O14543 in vivo 11071852 - X 2 P08069 O14543 in vitro 11071852 - X 2 P08069 O14543 in vivo 11071852 - X 2 P61073 O14543 in vivo 12163560 - X 2 P61073 O14543 in vitro 12163560 - X 2 P61073 O14543 in vivo 12163560 - X 2 P61073 O14543 in vitro 12163560 - X 2 O14543 anti tag coimmunoprecipitation 15601820 association C 5 O14543 anti tag coimmunoprecipitation 15601820 association C 5 O14543 P19235 pull down 10882725 association X 2 O14543 P20936 pull down 11331873 association X 2 O14543 P20936 coimmunoprecipitation 11331873 association X 2 O14543 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 O14543 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 O14543 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 O14543 I6L996 two hybrid prey pooling approach 25416956 physical association X 2 O14543 P07947 two hybrid prey pooling approach 25416956 physical association X 2 O14543 I6L996 two hybrid array 25416956 physical association X 2 O14543 P07947 two hybrid array 25416956 physical association X 2 O14543 I6L996 validated two hybrid 25416956 physical association X 2 O14543 P07947 validated two hybrid 25416956 physical association X 2 P10275 O14543 fluorescence polarization spectroscopy 24728074 direct interaction X 2 O14543 O60674 pull down 10421843 association X 2 O14543 Q99665 pull down 14559241 association X 2 O14543 Q13526 two hybrid pooling approach 16169070 physical association X 2 O14543 Q66K74 two hybrid 19027008 physical association X 2 O14543 Q66K74 two hybrid 19027008 physical association X 2 O14543 Q66K74 pull down 19027008 physical association X 2 O14543 Q66K74 fluorescence microscopy 19027008 colocalization X 2 O14543 Q66K74 two hybrid 19027008 physical association X 2 O14543 Q66K74 two hybrid 19027008 physical association X 2 O14543 Q15759 two hybrid 21900206 physical association X 2 O14543 Q16659 two hybrid 21900206 physical association X 2 O14543 P56159 two hybrid array 21988832 physical association X 2 O14543 P00533 ubiquitin reconstruction 24658140 physical association X 2 O14543 A0A024R759 fluorescence polarization spectroscopy 24728074 direct interaction X 2 O14543 Q13480 fluorescence polarization spectroscopy 24728074 direct interaction X 2 O14543 Q13480 fluorescence polarization spectroscopy 24728074 direct interaction X 2 O14543 Q13480 fluorescence polarization spectroscopy 24728074 direct interaction X 2 O14543 Q13480 fluorescence polarization spectroscopy 24728074 direct interaction X 2 O14543 Q8N8K9 two hybrid prey pooling approach 25416956 physical association X 2 O14543 Q8N8K9 two hybrid array 25416956 physical association X 2 O14543 Q8N8K9 validated two hybrid 25416956 physical association X 2 O15530 O14543 two hybrid 21900206 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B SOCS3 PTK2B MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 18507841,9344848 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_212880|BIOGRID_115629 bait|bait prey|prey SOCS3 TFDP1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18687693 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_222917|BIOGRID_222918 bait|bait prey|prey SOCS3 JAK3 MI:0492(in vitro)|MI:0004(affinity chromatography technology) 10373548,15385932 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_25322|BIOGRID_214146 -|prey -|bait SOCS3 UBC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21963094,22084247 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_211161|BIOGRID_264166 bait|prey prey|bait SOCS3 ABL1 MI:0004(affinity chromatography technology) 22787435 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_260802 bait prey SOCS3 EGFR MI:0004(affinity chromatography technology)|MI:0493(in vivo) 12070153 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_111229|HPRD_33639 prey|- bait|- SOCS3 CXCR4 MI:0004(affinity chromatography technology)|MI:0493(in vivo) 12163560 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_101021|HPRD_38018 bait|- prey|- SOCS3 IL2RB MI:0004(affinity chromatography technology)|MI:0492(in vitro) 10373548 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_214216|HPRD_24675 bait|- prey|- SOCS3 NFKBIA MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21451109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_213409|BIOGRID_213413 bait|prey prey|bait SOCS3 MAP1S MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19027008 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) UniProt_97836|MINT_68820|UniProt_97835|UniProt_97838|UniProt_97837|UniProt_97834|BIOGRID_211237|MINT_39557|MINT_39558|BIOGRID_211236|MINT_68826|MINT_68825|MINT_68824|MINT_39553|UniProt_97839|MINT_68823|BIOGRID_211235|MINT_39555|MINT_68821|MINT_39556|MINT_39552 bait|bait|bait|bait|bait|bait|bait|bait|neutral component|prey|neutral component|bait|bait|bait|neutral component|bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey|prey|prey|neutral component|bait|neutral component|prey|prey|prey|neutral component|prey|prey|prey|prey|prey|prey SOCS3 BIK MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_118652|BIOGRID_287122 unspecified role|prey unspecified role|bait SOCS3 RBMX MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_286023|UniProt_119728 prey|unspecified role bait|unspecified role SOCS3 GAB1 MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy) 24728074 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(intact)|(intact) UniProt_132432|UniProt_132626|UniProt_132602|UniProt_132641 neutral component|neutral component|neutral component|neutral component neutral component|neutral component|neutral component|neutral component SOCS3 PIN1 MI:0492(in vitro)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|MI:0471(mint)|(intact)|(biogrid)|MI:0471(mint) HPRD_21651|MINT_62166|UniProt_154938|BIOGRID_95406|MINT_33225 -|bait|bait|bait|bait -|prey|prey|prey|prey SOCS3 PTK6 MI:0401(biochemical)|MI:0401(biochemical) 22547065 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0403(colocalization) (biogrid)|(biogrid) BIOGRID_212873|BIOGRID_212874 prey|bait bait|prey SOCS3 HIVEP1 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_285759|UniProt_118968 prey|unspecified role bait|unspecified role SOCS3 RNF7 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 15601820 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(biogrid) UniProt_164443|UniProt_164454|UniProt_80337|UniProt_80326|BIOGRID_250323 bait|bait|bait|bait|bait prey|prey|prey|prey|prey SOCS3 FGFR3 MI:0004(affinity chromatography technology) 16410555 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_213165 bait prey SOCS3 RNF31 MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_119880|BIOGRID_288452 unspecified role|prey unspecified role|bait SOCS3 PTPN11 MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 10777583,12403768,17138568 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) BIOGRID_101299|HPRD_16601|BIOGRID_212900|BIOGRID_101297|BIOGRID_212354 prey|-|bait|prey|prey bait|-|prey|bait|bait NME4 SOCS3 MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_119161|BIOGRID_285626 unspecified role|bait unspecified role|prey SOCS3 CSF1R MI:0493(in vivo)|MI:0004(affinity chromatography technology) 12133942 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_39033|BIOGRID_107332 -|bait -|prey SOCS3 TFR2 MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_119299|BIOGRID_287833 unspecified role|bait unspecified role|prey SOCS3 MAPK8IP1 MI:0004(affinity chromatography technology) 18055217 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_211029 bait prey SOCS3 TES MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_288267|UniProt_119709 bait|unspecified role prey|unspecified role SOCS3 MAP3K7 MI:0004(affinity chromatography technology) 16543409 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124617 bait prey SOCS3 IGF1R MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0493(in vivo) 11071852 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|- (biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_115725|BIOGRID_115726|BIOGRID_115727|HPRD_36300 bait|prey|bait|- prey|bait|prey|- SOCS3 TXNDC11 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_288408|UniProt_119842 bait|unspecified role prey|unspecified role SOCS3 PPP3CB MI:0493(in vivo) 11970967 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_10550 - - SOCS3 PTK2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16007195,18031698 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_154593|BIOGRID_219142|BIOGRID_154592 bait|prey|prey prey|bait|bait SOCS3 MET MI:0053(fluorescence polarization spectroscopy) 24728074 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (intact) UniProt_133065 neutral component neutral component SOCS3 PRLR MI:0004(affinity chromatography technology)|MI:0493(in vivo) 11713228 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_96486|HPRD_1337 bait|- prey|- SOCS3 JAK1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 10373548,10707961 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|- (biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_214215|BIOGRID_214213|BIOGRID_214214|BIOGRID_212461|HPRD_24363 bait|bait|prey|prey|- prey|prey|bait|bait|- SOCS3 PDPK1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_159425|BIOGRID_157225|UniProt_180023 prey|prey|prey bait|bait|bait SOCS3 RASA1 MI:0492(in vitro)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 11331873 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0914(association) MI:0468(hprd)|(intact)|(intact)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint) HPRD_34981|UniProt_69127|UniProt_69128|BIOGRID_107400|MINT_80147|MINT_80146|MINT_48162|BIOGRID_107399|MINT_48163 -|unspecified role|unspecified role|bait|unspecified role|unspecified role|unspecified role|bait|unspecified role -|unspecified role|unspecified role|prey|unspecified role|unspecified role|unspecified role|prey|unspecified role SOCS3 GFRA1 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_287368|UniProt_117122 prey|unspecified role bait|unspecified role SOCS3 LEPR MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0493(in vivo) 11018044,21239736 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_138871|BIOGRID_101273|HPRD_8175 prey|bait|- bait|prey|- SOCS3 APP MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_227917 bait prey SOCS3 RELA MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21451109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_213407|BIOGRID_213411 bait|prey prey|bait SOCS3 BCL10 MI:0493(in vivo) 15213237 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25703 - - SOCS3 CSF3R MI:0493(in vivo) 12133942 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_12922 - - SOCS3 REL MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21451109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_213408|BIOGRID_213412 bait|prey prey|bait SOCS3 IL12RB2 MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 14559241 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association) (intact)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(biogrid) UniProt_72862|MINT_47984|BIOGRID_212021|MINT_79943|BIOGRID_212022 unspecified role|unspecified role|prey|unspecified role|prey unspecified role|unspecified role|bait|unspecified role|bait SOCS3 MAP3K5 MI:0004(affinity chromatography technology) 16407264 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124852 prey bait SOCS3 IRS1 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12228220,15514089 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_36378|BIOGRID_214886|BIOGRID_214879 -|bait|prey -|prey|bait SOCS3 DAB1 MI:0004(affinity chromatography technology) 17974915 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_201393 bait prey SOCS3 LCK MI:0004(affinity chromatography technology) 21234523 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_214639 prey bait SOCS3 INSR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0492(in vitro)|MI:0004(affinity chromatography technology) 12560330,15514089 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|(biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_214752|BIOGRID_96694|HPRD_36503|BIOGRID_214888 prey|prey|-|bait bait|bait|-|prey SOCS3 JAK2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0493(in vivo)|MI:0096(pull down) 10421843,10882725,11314018,15514089,19543316,22342841,9344848 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association)|-|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_209325|BIOGRID_214885|BIOGRID_214751|BIOGRID_102170|MINT_47980|BIOGRID_101656|BIOGRID_101657|BIOGRID_208629|UniProt_66965|BIOGRID_115630|BIOGRID_115628|BIOGRID_102168|MINT_79939|BIOGRID_102169|HPRD_36703|BIOGRID_214212 bait|bait|prey|prey|unspecified role|prey|bait|bait|unspecified role|prey|bait|prey|unspecified role|bait|-|bait prey|prey|bait|bait|unspecified role|bait|prey|prey|unspecified role|bait|prey|bait|unspecified role|prey|-|prey SOCS3 TRAF6 MI:0004(affinity chromatography technology) 16543409 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124618 bait prey SOCS3 IRS2 MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 15514089 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_214880|HPRD_24350|BIOGRID_214887 prey|-|bait bait|-|prey SOCS3 TNFSF10 MI:0004(affinity chromatography technology) 21308719 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_213621 bait prey SOCS3 MAPK11 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_157165|UniProt_158988|UniProt_179586 prey|prey|prey bait|bait|bait SOCS2 SOCS3 MI:0004(affinity chromatography technology)|MI:0492(in vitro) 16199887 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_211608|HPRD_25720 prey|- bait|- SOCS3 SIGLEC7 MI:0004(affinity chromatography technology) 17138568 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_212899 bait prey SOCS3 EPOR MI:0493(in vivo)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology) 10882725,12027890 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0914(association)|MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(intact)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid) HPRD_33727|UniProt_66890|BIOGRID_101660|MINT_80190|MINT_48203|BIOGRID_101658|BIOGRID_112767|BIOGRID_101659 -|unspecified role|bait|unspecified role|unspecified role|bait|prey|prey -|unspecified role|prey|unspecified role|unspecified role|prey|bait|bait SOCS3 RPL7A MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_119253|BIOGRID_285968 unspecified role|prey unspecified role|bait SOCS3 NFKB1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21451109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_213406|BIOGRID_213410 bait|prey prey|bait SOCS3 AR MI:0053(fluorescence polarization spectroscopy) 24728074 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (intact) UniProt_132303 neutral component neutral component SOCS3 CUEDC2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22084247 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_211156|BIOGRID_211157|BIOGRID_211158 prey|prey|bait bait|bait|prey SOCS3 GHR MI:0493(in vivo)|MI:0004(affinity chromatography technology) 10585430 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_8034|BIOGRID_101893 -|prey -|bait SOCS3 KIT MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy) 24728074 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(intact) UniProt_132851|UniProt_132914|UniProt_132796 neutral component|neutral component|neutral component neutral component|neutral component|neutral component SOCS3 ETV6 MI:0004(affinity chromatography technology) 11314018 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_208628 bait prey SOCS3 NONO MI:0004(affinity chromatography technology) 18952062 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_116357 bait prey SOCS3 ACADVL MI:0018(two hybrid)|MI:0018(two hybrid) 22093833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_153759|BIOGRID_153760 bait|bait prey|prey SOCS3 TCEB2 MI:0004(affinity chromatography technology)|MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10051596,15601820,16007195,17135358 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(intact) BIOGRID_207408|HPRD_7721|BIOGRID_219144|BIOGRID_250324|UniProt_164443|UniProt_164454|UniProt_80337|UniProt_80326 bait|-|bait|bait|bait|bait|bait|bait prey|-|prey|prey|prey|prey|prey|prey SOCS3 TCEB1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10051596,12783885,15601820,17135358,22084247 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(intact)|(intact)|(intact)|(intact) BIOGRID_207409|BIOGRID_211162|BIOGRID_213163|BIOGRID_213162|HPRD_7727|BIOGRID_250325|UniProt_164443|UniProt_164454|UniProt_80337|UniProt_80326 bait|prey|prey|bait|-|bait|bait|bait|bait|bait prey|bait|bait|prey|-|prey|prey|prey|prey|prey SOCS3 CSNK1E MI:0493(in vivo) 15070676 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25419 - - SOCS3 CUL5 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15601820,17135358 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid) UniProt_164443|UniProt_164454|UniProt_80337|UniProt_80326|BIOGRID_250322|BIOGRID_207407 bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey SOCS3 VHL MI:0004(affinity chromatography technology) 21685897 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_199680 bait prey SOCS3 IL6ST MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 10777583,12403768 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|MI:0468(hprd)|(biogrid)|(biogrid) BIOGRID_101295|HPRD_7571|BIOGRID_101294|BIOGRID_212355 prey|-|prey|prey bait|-|bait|bait SOCS3 MAPK6 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_159122|BIOGRID_157553|UniProt_179720 prey|prey|prey bait|bait|bait

PPI - HINT Gene A Gene B PMID Method Quality SOCS3 JAK2 24354892,10421843,15514089,19543316,9344848,10882725,10421843,22342841,11314018,9344848,10421843 0096,0004,0004,0004,0096,0004,0018,0096,0004,0018,0096 LC SOCS3 EGFR 24658140,24658140,24658140,12070153 0090,0112,0004,0004 LC SOCS3 INSR 15514089,12560330,12560330 0004,0004,0018 LC SOCS3 EPOR 10882725,12027890,10882725 0096,0096,0004 LC SOCS3 JAK1 16459330,10373548,10373548,10373548,10373548,10707961 0007,0004,0415,0096,0059,0004 LC SOCS3 IL6ST 10777583,12403768,12403768 0096,0096,0004 LC SOCS3 LEPR 11018044,21239736 0096,0004 LC SOCS3 PTPN11 17138568,10777583,12403768,12403768 0004,0004,0004,0096 LC SOCS3 TCEB1 15601820,22084247,12783885,17135358,15601820,12783885 0007,0004,0004,0004,0004,0096 LC SOCS3 TCEB2 15601820,16007195,17135358,15601820 0007,0004,0004,0004 LC SOCS3 DKFZP666O0110 16007195,18031698 0004,0004 LC SOCS3 CUL5 17135358,15601820,15601820,24438103 0004,0004,0007,0096 LC SOCS3 RNF7 15601820,15601820,24438103 0004,0007,0096 LC SOCS3 TRAF6 16543409,26633718,16543409 0007,0004,0004 LC SOCS3 JAK2 24354892,10421843,15514089,19543316,9344848,10882725,10421843,22342841,11314018,9344848,10421843 0096,0004,0004,0004,0096,0004,0018,0096,0004,0018,0096 LC SOCS3 EGFR 24658140,24658140,24658140,12070153 0090,0112,0004,0004 LC SOCS3 INSR 15514089,12560330,12560330 0004,0004,0018 LC SOCS3 EPOR 10882725,12027890,10882725 0096,0096,0004 LC SOCS3 JAK1 16459330,10373548,10373548,10373548,10373548,10707961 0007,0004,0415,0096,0059,0004 LC SOCS3 IL6ST 10777583,12403768,12403768 0096,0096,0004 LC SOCS3 LEPR 11018044,21239736 0096,0004 LC SOCS3 PTPN11 17138568,10777583,12403768,12403768 0004,0004,0004,0096 LC SOCS3 TCEB1 15601820,22084247,12783885,17135358,15601820,12783885 0007,0004,0004,0004,0004,0096 LC SOCS3 TCEB2 15601820,16007195,17135358,15601820 0007,0004,0004,0004 LC SOCS3 DKFZP666O0110 16007195,18031698 0004,0004 LC SOCS3 CUL5 17135358,15601820,15601820,24438103 0004,0004,0007,0096 LC SOCS3 RNF7 15601820,15601820,24438103 0004,0007,0096 LC SOCS3 TRAF6 16543409,26633718,16543409 0007,0004,0004 LC NME4 SOCS3 21988832 0018 HT SOCS2 SOCS3 16199887,16199887 0004,0061 LC SOCS3 PDPK1 21900206 0018 HT SOCS3 JAK2 10421843,9344848,10421843,9344848,24438103,10421843 0004,0096,0018,0018,0415,0096 LC SOCS3 EGFR 24658140,25402006,24658140,24658140 0090,0018,0112,0004 LC SOCS3 INSR 11071852,12560330,12560330 0018,0004,0018 LC SOCS3 YES1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT SOCS3 IGF1R 11071852,11071852,11071852,11071852 0018,0019,0004,0096 LC SOCS3 MET 24728074 0053 HT SOCS3 AR 24728074 0053 HT SOCS3 KIT 24728074 0053 HT SOCS3 PKM 24606918 0424 LC SOCS3 IL2RB 10373548,10373548 0096,0059 LC SOCS3 HIVEP1 21988832 0018 HT SOCS3 RASA1 11331873,11331873,11331873 0019,0096,0004 LC SOCS3 JAK1 10373548,10373548,10373548,10373548 0004,0415,0096,0059 LC SOCS3 YWHAQ 25814554,25814554 0397,0018 HT SOCS3 AXL 12470648 0018 LC SOCS3 RBMX 21988832 0018 HT SOCS3 IL6ST 24438103 0415 LC SOCS3 ACADVL 22093833,22093833 0018,0096 LC SOCS3 GFRA1 21988832,21988832 0397,0018 HT SOCS3 RPL7A 21988832 0018 HT SOCS3 PTK2 25416956,25416956,25416956 1112,0397,1356 HT SOCS3 TRDN 25814554,25814554,25814554 0397,0018,1356 HT SOCS3 BIK 21988832 0018 HT SOCS3 GAB1 24728074 0053 HT SOCS3 PIN1 16169070,16169070 0018,0398 HT SOCS3 TFDP1 18687693,18687693,18687693 0007,0004,0018 LC SOCS3 PTK2B 9344848 0018 LC SOCS3 MAPK11 21900206 0018 HT SOCS3 MAPK6 21900206 0018 HT SOCS3 DKFZP666O0110 25416956 0018 HT SOCS3 MAP1S 19027008,19027008,19027008,19027008 0004,0018,0416,0096 LC SOCS3 TXNDC11 21988832 0018 HT SOCS3 KIAA1958 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT SOCS3 RNF31 21988832 0018 HT SOCS3 CUEDC2 22084247,22084247,22084247 0018,0096,0004 LC SOCS3 SH2D2A 25814554,25814554,25814554 0397,0018,1356 HT SOCS3 TES 21988832 0018 HT SOCS3 TFR2 21988832 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P08069 O14543 IGF1R SOCS3 0.623 11071852 P10721 O14543 KIT SOCS3 0.183 24728074 P10912 O14543 GHR SOCS3 0.309 10585430 P06239 O14543 LCK SOCS3 0.21 21234523 O95863 O14543 SNAI1 SOCS3 0.21 25203322 P07947 O14543 YES1 SOCS3 0.454 25416956 P15822 O14543 HIVEP1 SOCS3 0.332 21988832 Q96EP0 O14543 RNF31 SOCS3 0.332 21988832 Q16659 O14543 MAPK6 SOCS3 0.332 21900206 Q15369 O14543 TCEB1 SOCS3 0.74 22084247,12783885,15601820,17135358 P23458 O14543 JAK1 SOCS3 0.702 10707961,10373548 O14543 J3QRU1 SOCS3 YES1 {ECO:0000313|ENSEMBL:ENSP00000464380} 0.236 unassigned1304 P19235 O14543 EPOR SOCS3 0.765 10882725,12027890 Q14289 O14543 PTK2B SOCS3 0.454 9344848,18507841 P49748 O14543 ACADVL SOCS3 0.523 22093833 P27348 O14543 YWHAQ SOCS3 0.286 25814554 Q14186 O14543 TFDP1 SOCS3 0.454 18687693 P51451 O14543 BLK SOCS3 0.236 unassigned1304 P56159 O14543 GFRA1 SOCS3 0.286 21988832 Q13061 O14543 TRDN SOCS3 0.376 25814554 Q9NP31 O14543 SH2D2A SOCS3 0.376 25814554 Q99665 O14543 IL12RB2 SOCS3 0.569 14559241 Q66K74 O14543 MAP1S SOCS3 0.902 19027008 Q15370 O14543 TCEB2 SOCS3 0.523 16007195,17135358,15601820 P00533 O14543 EGFR SOCS3 0.597 24658140,12070153,25402006 O60674 O14543 JAK2 SOCS3 0.989 10421843,10882725,22342841,15514089,19543316,24354892,24438103,9344848,11314018 Q93034 O14543 CUL5 SOCS3 0.583 24438103,17135358,15601820 P25963 O14543 NFKBIA SOCS3 0.376 21451109 P38159 O14543 RBMX SOCS3 0.332 21988832 P35568 O14543 IRS1 SOCS3 0.376 15514089 Q99683 O14543 MAP3K5 SOCS3 0.21 16407264 Q9UBF6 O14543 RNF7 SOCS3 0.472 15601820,24438103 Q9UGI8 O14543 TES SOCS3 0.332 21988832 Q9UP52 O14543 TFR2 SOCS3 0.332 21988832 P62424 O14543 RPL7A SOCS3 0.332 21988832 P14618 O14543 PKM SOCS3 0.033 24606918 P48357 O14543 LEPR SOCS3 0.454 11018044,21239736 Q13323 O14543 BIK SOCS3 0.332 21988832 Q13526 O14543 PIN1 SOCS3 0.286 16169070 O14543 I6L996 SOCS3 PTK2 {ECO:0000313|EMBL:AAH28733.1} 0.332 25416956 P19838 O14543 NFKB1 SOCS3 0.376 21451109 Q15717 O14543 ELAVL1 SOCS3 0.21 23686487 P52333 O14543 JAK3 SOCS3 0.21 15385932 Q15759 O14543 MAPK11 SOCS3 0.332 21900206 Q13480 O14543 GAB1 SOCS3 0.332 24728074 P20936 O14543 RASA1 SOCS3 0.659 11331873 O14543 O00746 SOCS3 NME4 0.332 21988832 Q04206 O14543 RELA SOCS3 0.376 21451109 O14543 O14508 SOCS3 SOCS2 0.21 16199887 O15530 O14543 PDPK1 SOCS3 0.332 21900206 O43318 O14543 MAP3K7 SOCS3 0.21 16543409 O75553 O14543 DAB1 SOCS3 0.21 17974915 P00519 O14543 ABL1 SOCS3 0.21 22787435 P05067 O14543 APP SOCS3 0.183 21832049 P06213 O14543 INSR SOCS3 0.507 12560330,15514089 P07333 O14543 CSF1R SOCS3 0.21 12133942 P08581 O14543 MET SOCS3 0.183 24728074 P10275 O14543 AR SOCS3 0.183 24728074 P14784 O14543 IL2RB SOCS3 0.309 10373548 P16471 O14543 PRLR SOCS3 0.21 11713228 P22607 O14543 FGFR3 SOCS3 0.21 16410555 P40189 O14543 IL6ST SOCS3 0.74 24438103,12403768,10777583 P40337 O14543 VHL SOCS3 0.21 21685897 P41212 O14543 ETV6 SOCS3 0.21 11314018 P50591 O14543 TNFSF10 SOCS3 0.21 21308719 P61073 O14543 CXCR4 SOCS3 0.21 12163560 P62869 O14543 TCEB2 SOCS3 0.126 15601820 P83940 O14543 TCEB1 SOCS3 0.126 15601820 Q04864 O14543 REL SOCS3 0.376 21451109 Q05397 O14543 PTK2 SOCS3 0.597 25416956,16007195,18031698 Q06124 O14543 PTPN11 SOCS3 0.659 17138568,12403768,10777583 Q15233 O14543 NONO SOCS3 0.21 18952062 Q6PKC3 O14543 TXNDC11 SOCS3 0.332 21988832 Q8N8K9 O14543 KIAA1958 SOCS3 0.583 25416956,unassigned1304 Q9D5V5 O14543 CUL5 SOCS3 0.126 15601820 Q9H467 O14543 CUEDC2 SOCS3 0.702 22084247 Q9UHD2 O14543 TBK1 SOCS3 0.623 25939384 Q9UQF2 O14543 MAPK8IP1 SOCS3 0.21 18055217 Q9WTZ1 O14543 RNF7 SOCS3 0.126 15601820 Q9Y286 O14543 SIGLEC7 SOCS3 0.21 17138568 Q9Y4H2 O14543 IRS2 SOCS3 0.376 15514089 Q9Y4K3 O14543 TRAF6 SOCS3 0.376 26633718,16543409

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 NME4 SOCS3 MI:0045 experimental interaction detection MI:0461 interaction database SOCS2 SOCS3 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 PDPK1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 MAP3K7 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 JAK2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 DAB1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 SNAI1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 BCL10 MI:0362 inference MI:0461 interaction database SOCS3 ABL1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 EGFR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 GH1 MI:0362 inference MI:1106 pathways database SOCS3 GH2 MI:0362 inference MI:1106 pathways database SOCS3 IFNA1 MI:0362 inference MI:1106 pathways database SOCS3 IFNA2 MI:0362 inference MI:1106 pathways database SOCS3 IFNA10 MI:0362 inference MI:1106 pathways database SOCS3 IFNA7 MI:0362 inference MI:1106 pathways database SOCS3 IFNA21 MI:0362 inference MI:1106 pathways database SOCS3 IFNA5 MI:0362 inference MI:1106 pathways database SOCS3 IFNA14 MI:0362 inference MI:1106 pathways database SOCS3 IFNA17 MI:0362 inference MI:1106 pathways database SOCS3 IFNB1 MI:0362 inference MI:1106 pathways database SOCS3 IFNG MI:0362 inference MI:1106 pathways database SOCS3 IFNA6 MI:0362 inference MI:1106 pathways database SOCS3 IFNA4 MI:0362 inference MI:1106 pathways database SOCS3 IFNA16 MI:0362 inference MI:1106 pathways database SOCS3 APP MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 IL6 MI:0362 inference MI:1106 pathways database SOCS3 INSR MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 LCK MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 CSF1R MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 YES1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 IGF1R MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 MET MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 IL6R MI:0362 inference MI:1106 pathways database SOCS3 UBC MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 AR MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 KIT MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 GHR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 PKM MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 IL2RB MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 IDO1 MI:0362 inference MI:0461 interaction database SOCS3 IFNGR1 MI:0362 inference MI:1106 pathways database SOCS3 HIVEP1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 PRLR MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 IFNAR1 MI:0362 inference MI:1106 pathways database SOCS3 EPOR MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 NFKB1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 RASA1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 TAF1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 FGFR3 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 JAK1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 NFKBIA MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 YWHAQ MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 TYK2 MI:0362 inference MI:1106 pathways database SOCS3 IFNA8 MI:0362 inference MI:1106 pathways database SOCS3 IRS1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 RBMX MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 IFNGR2 MI:0362 inference MI:1106 pathways database SOCS3 IL6ST MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 VHL MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 LEP MI:0362 inference MI:1106 pathways database SOCS3 ETV6 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 LEPR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 IFNAR2 MI:0362 inference MI:1106 pathways database SOCS3 ACADVL MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 TNFSF10 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 JAK3 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 STAT2 MI:0362 inference MI:1106 pathways database SOCS3 GFRA1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 CXCR4 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 LMO4 MI:0362 inference MI:0461 interaction database SOCS3 RPL7A MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 RBX1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SOCS3 RELA MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 REL MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 PTK2 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 PTPN11 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 TRDN MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 BIK MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 GAB1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 PIN1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 CUL2 MI:0362 inference MI:0461 interaction database SOCS3 PTK6 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 TFDP1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 PTK2B MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 NONO MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 TCEB1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 TCEB2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 ELAVL1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 MAPK11 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 MAPK6 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 MAP1S MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 TXNDC11 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 IDO2 MI:0362 inference MI:0461 interaction database SOCS3 KIAA1958 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 CUL5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS3 RNF31 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 IL12RB2 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 MAP3K5 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 CUEDC2 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 NOD2 MI:0362 inference MI:0461 interaction database SOCS3 SH2D2A MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 RNF7 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 TES MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 TBK1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 TFR2 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 MAPK8IP1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 SIGLEC7 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 IRS2 MI:0045 experimental interaction detection MI:0461 interaction database SOCS3 TRAF6 MI:0045 experimental interaction detection MI:0461 interaction database