Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 50945526 rs3789576 G T rs3789576 9.78E-04 GEMCITABINE|CYTARABINE MANNOSYLTRANSFERASES|PIGB PROTEIN, HUMAN|RNA, SMALL INTERFERING|DEOXYCYTIDINE Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 G intron GWASdb_drug 1 50907438 rs4381241 T C rs4381241 1.50E-04 Alcohol dependence HPOID:0000707 DOID:0050741 C intron GWASdb_trait 1 50907438 rs4381241 T C rs4381241 1.70E-04 Alcohol dependence HPOID:0000707 DOID:0050741 C intron GWASdb_trait 1 50909985 rs17106184 G A rs17106184 4.00E-09 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 1 50911347 rs956084 C T rs956084 1.50E-10 HDL cholesterol HPOID:0003107 DOID:14502|DOID:1461|DOID:3393 G intron GWASdb_trait 1 50912441 rs12134715 A C rs12134715 2.38E-05 Personality dimensions HPOID:0012075 DOID:1510 A intron GWASdb_trait 1 50912441 rs12134715 A C rs12134715 1.37E-05 Self-reported allergy HPOID:0002715 DOID:0060056 A intron GWASdb_trait 1 50917596 rs12565493 T C rs12565493 2.47E-05 Personality dimensions HPOID:0012075 DOID:1510 T intron GWASdb_trait 1 50917596 rs12565493 T C rs12565493 1.57E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 50918388 rs12142848 C T rs12142848 2.41E-05 Personality dimensions HPOID:0012075 DOID:1510 C intron GWASdb_trait 1 50918388 rs12142848 C T rs12142848 1.60E-05 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 1 50919942 rs12133928 T C rs12133928 2.66E-05 Personality dimensions HPOID:0012075 DOID:1510 T intron GWASdb_trait 1 50919942 rs12133928 T C rs12133928 1.48E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 50931102 rs12063722 C T rs12063722 5.85E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 1 50931160 rs12562938 C T rs12562938 3.25E-05 Personality dimensions HPOID:0012075 DOID:1510 C intron GWASdb_trait 1 50937848 rs3827730 T C rs3827730 1.40E-06 Alcohol dependence HPOID:0000707 DOID:0050741 T intron GWASdb_trait 1 50937848 rs3827730 T C rs3827730 4.10E-05 Alcohol dependence HPOID:0000707 DOID:0050741 T intron GWASdb_trait 1 50937848 rs3827730 T C rs3827730 4.00E-06 Depression and alcohol dependence HPOID:0000716 DOID:303|DOID:1596 T intron GWASdb_trait 1 50937848 rs3827730 T C rs3827730 1.42E-06 Alcoholism HPOID:0000707 DOID:0050741 T intron GWASdb_trait 1 50937848 rs3827730 T C rs3827730 4.08E-05 Alcoholism HPOID:0000707 DOID:0050741 T intron GWASdb_trait 1 50945526 rs3789576 G T rs3789576 9.78E-04 Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 G intron GWASdb_trait 1 50949724 rs12116432 A T rs12116432 3.65E-05 Personality dimensions HPOID:0012075 DOID:1510 A intron GWASdb_trait 1 50949724 rs12116432 A T rs12116432 2.14E-05 Self-reported allergy HPOID:0002715 DOID:0060056 A intron GWASdb_trait 1 50983135 rs9645408 T C rs9645408 3.28E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 50986057 rs11205726 C T rs11205726 4.30E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 50991426 rs10888691 G C rs10888691 4.37E-05 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 1 50997461 rs12135541 T C rs12135541 4.82E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 50999860 rs12137729 T C rs12137729 4.44E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 51029387 rs3789584 T C rs3789584 2.22E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 1 51029609 rs12118892 G T rs12118892 2.00E-05 Urinary metabolites HPOID:0000079 DOID:557 G intron GWASdb_trait 1 51029609 rs12118892 G T rs12118892 4.88E-05 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 1 51034926 rs12073534 T C rs12073534 6.90E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 51043243 rs12122697 G T rs12122697 6.04E-05 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 1 51051105 rs3789585 G C rs3789585 6.13E-05 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 1 51060054 rs11205738 G A rs11205738 6.10E-05 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 1 51076822 rs12568008 G A rs12568008 2.00E-05 Urinary metabolites HPOID:0000079 DOID:557 G intron GWASdb_trait 1 51076822 rs12568008 G A rs12568008 5.47E-05 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 1 51078564 rs17106336 T C rs17106336 2.78E-04 Multiple complex diseases HPOID:0000118 NA T intron GWASdb_trait 1 51078564 rs17106336 T C rs17106336 1.20E-05 Urinary metabolites HPOID:0000079 DOID:557 T intron GWASdb_trait 1 51078564 rs17106336 T C rs17106336 5.65E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 51079296 rs11205741 C A rs11205741 6.93E-05 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 1 51086337 rs10888700 T C rs10888700 1.22E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 1 51086847 rs11577903 T C rs11577903 4.45E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 51087465 rs11205743 C G rs11205743 9.30E-06 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 1 51087465 rs11205743 C G rs11205743 4.72E-05 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 1 51090942 rs10788929 T C rs10788929 8.81E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 51092829 rs12120719 T C rs12120719 1.95E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 51094117 rs11577260 G A rs11577260 6.61E-05 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 1 51100042 rs11205748 A G rs11205748 7.42E-05 Self-reported allergy HPOID:0002715 DOID:0060056 A intron GWASdb_trait 1 51110167 rs12567589 C T rs12567589 7.73E-05 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 1 51113531 rs11205750 A G rs11205750 7.60E-05 Self-reported allergy HPOID:0002715 DOID:0060056 A intron GWASdb_trait 1 51116645 rs11205752 T C rs11205752 7.12E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 1 51118706 rs10888703 C A rs10888703 6.58E-05 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 1 51123315 rs12117653 C A rs12117653 7.42E-05 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 1 51174330 rs11205760 C T rs11205760 1.67E-05 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 1 51174330 rs11205760 C T rs11205760 3.40E-05 Alcohol dependence HPOID:0000707 DOID:0050741 C intron GWASdb_trait 1 51174330 rs11205760 C T rs11205760 6.90E-04 Alcohol dependence HPOID:0000707 DOID:0050741 C intron GWASdb_trait 1 51174330 rs11205760 C T rs11205760 3.37E-05 Alcoholism HPOID:0000707 DOID:0050741 C intron GWASdb_trait 1 51188674 rs6680846 G C rs6680846 3.16E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 1 51304834 rs12239279 G A rs12239279 1.48E-05 Height HPOID:0000002 NA G intron GWASdb_trait 1 51410517 rs12092977 T C rs12092977 6.40E-15 HDL cholesterol HPOID:0003107 DOID:14502|DOID:1461|DOID:3393 T intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs11587909 1 51050799 51050799 intronic 0.971332 0.0126323034350116 GWAS of prostate cancer rs17383851 1 51095318 51095318 intronic 0.97075 0.0128926007819148 GWAS of prostate cancer rs1846522 1 50981205 50981205 intronic 0.926319 0.0332394279160947 GWAS of prostate cancer rs11585772 1 51384790 51384790 intronic 0.881949 0.0545565278602036 GWAS of prostate cancer rs12746642 1 51119769 51119769 intronic 0.878971 0.05602545342195 GWAS of prostate cancer rs1849553 1 51318005 51318005 intronic 0.852257 0.069429423013253 GWAS of prostate cancer rs3789576 1 50945526 50945526 intronic 0.825918 0.0830630687998432 GWAS of prostate cancer rs3789587 1 51266474 51266474 intronic 0.822263 0.0849892515836669 GWAS of prostate cancer rs12089041 1 51381594 51381594 intronic 0.818411 0.0870285420437016 GWAS of prostate cancer rs9803853 1 51094008 51094008 intronic 0.79583 0.0991796935021671 GWAS of prostate cancer rs7535374 1 50966897 50966897 intronic 0.765077 0.116294853745392 GWAS of prostate cancer rs10493152 1 51128777 51128777 intronic 0.751713 0.12394793907219 GWAS of prostate cancer rs11577260 1 51094117 51094117 intronic 0.731412 0.135837918634246 GWAS of prostate cancer rs11581155 1 50976306 50976306 intronic 0.704373 0.152197299745856 GWAS of prostate cancer rs12567589 1 51110167 51110167 intronic 0.702295 0.153480423538917 GWAS of prostate cancer rs7543272 1 51069102 51069102 intronic 0.551949 0.258101049158171 GWAS of prostate cancer rs12142848 1 50918388 50918388 intronic 0.531457 0.274531868333877 GWAS of prostate cancer rs12759925 1 51134336 51134336 intronic 0.467763 0.329974133812324 GWAS of prostate cancer rs6695869 1 51413205 51413205 intronic 0.464105 0.333383752717121 GWAS of prostate cancer rs12085479 1 51199116 51199116 intronic 0.457862 0.339265399003707 GWAS of prostate cancer rs7515597 1 51159347 51159347 intronic 0.409337 0.38791899767192 GWAS of prostate cancer rs10888690 1 50960521 50960521 intronic 0.339156 0.469600495438582 GWAS of prostate cancer rs1149795 1 50972564 50972564 intronic 0.167141 0.776917003789147 GWAS of prostate cancer rs1464081 1 51335094 51335094 intronic 0.156886 0.804415809721055 GWAS of prostate cancer rs6692340 1 51280132 51280132 intronic 0.121838 0.9142172386616131 GWAS of prostate cancer rs3827730 1 50937848 50937848 intronic 0.02936 1.53224394875597

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000185104.19 FAF1 604460