PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SOCS1 TCEB3 10051596 biogrid exp GP GP P P GP GP GP GP GP GP G GP P G GP G GP P GP P GP G GP GP G SOCS1 TP53 20005840 biogrid exp G G G G G G G G G GP G G G GP G GP G G GP G SOCS1 CUL4B 23238014 intact exp GP GP P P GP GP GP GP G GP G GP P G GP G GP P GP P GP GP GP GP G SOCS1 CYTIP 23469018 biogrid exp GP P P P P GP GP GP GP GP G GP P GP GP P P GP P GP GP GP P G SOCS1 IRF3 21079688 biogrid exp GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP GP GP GP GP G SOCS1 TRAF6 bci exp GP GP P GP GP GP GP GP G G GP GP G G GP P GP GP GP GP GP G SOCS1 CEBPA bci exp GP G P P GP G GP G GP G G GP P G GP G GP P G GP G GP GP G SOCS1 VHL 21685897 biogrid exp G G G G GP GP GP G G G G P G G P GP G G G GP G SOCS1 PDCD1 21263070 innatedb,biogrid exp G G GP G G G SOCS1 NMI bci exp GP GP P GP GP GP GP GP GP G GP P G GP G GP P GP P GP GP GP GP G SOCS1 TNFRSF1A bci exp GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 TNFRSF1B bci exp GP GP P P GP GP GP GP GP GP G GP P GP GP GP P GP P GP GP GP P G SOCS1 IRAK1 bci exp GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP GP GP GP GP G SOCS1 CLEC7A 21899704 biogrid exp G G P GP GP GP GP G GP G GP P GP G G G P GP GP GP P SOCS1 ETV6 11314018 biogrid exp GP G P P GP GP G G GP GP G GP P G GP G GP P GP P GP GP GP GP G SOCS1 CCR1 bci exp G G G G G G G G G G G G G G G G G G G SOCS1 CXCR4 12163560 hprd,bci exp G G G G G G G G G G G G G G G G G G G G SOCS1 DAB1 17974915 biogrid exp G P GP G G G G GP P G G P GP G SOCS1 IL2RB 11133764 hprd,biogrid,bci exp G G P G G G G G GP G G G G G G G G GP G G G SOCS1 TUBA3C, TUBA3D 19327355 mint,intact exp P P P P P P P P P P P P P P SOCS1 ATR 20005840 biogrid exp G GP P GP GP GP GP GP G G G P G GP G GP G G G G GP G SOCS1 IFNAR2 bci exp G GP P P GP GP G G GP G G G P G G G GP P G G GP GP GP G SOCS1 TYR bci exp G G G G G G G G G G G G G G G G G G SOCS1 ATM 20005840 biogrid exp GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 EZH2 23238014 intact exp GP P P GP P GP G GP G P P P GP GP GP GP SOCS1 TEK 10022833 hprd,i2d,bci exp, ortho G GP P P GP GP G G GP GP G GP P G GP G G P GP GP GP P G SOCS1 STAT2 bci exp, ortho GP GP P P G GP GP G GP GP G GP P G GP G GP P GP P GP G GP GP G SOCS1 TUBG1 15456882 biogrid exp, ortho GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 RELA 17183367,14690596,21084693, 25402006 innatedb,hprd,biogrid,mint,intact,bci exp, ortho, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 INSR 11342531,15169905, 25402006, 23023127, 21836163 hprd,biogrid,i2d exp, ortho, pred GP GP P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 TIRAP 16415872, 25402006 innatedb,hprd,biogrid exp, ortho, pred G GP P GP GP GP G G G G GP P GP GP G GP GP P GP G GP GP G SOCS1 EGFR 16273093,12070153, 25402006, 23023127 hprd,biogrid,i2d exp, ortho, pred GP GP P G GP GP GP G G G GP P G G G GP P G P GP G GP GP G SOCS1 KIT 10022833, 25402006, 23023127 hprd,biogrid,i2d exp, ortho, pred G G P P G G G GP G G G P GP G G G G G G G G G SOCS1 VAV1 10022833,10747851, 25402006, 23023127 hprd,biogrid,i2d,bci exp, ortho, pred GP GP P P P P P GP GP GP G GP P G GP G GP GP P P GP GP GP G SOCS1 TYK2 21757742, 25402006, 21836163 biogrid,bci exp, ortho, pred GP GP P P GP GP GP GP GP G G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 ERBB2 16273093, 25402006, 23023127, 21836163 biogrid,i2d,mint,intact exp, ortho, pred GP G G GP GP G G G G GP G G G GP P G GP G G G G SOCS1 IFNGR1 15522878, 25402006, 21836163 hprd,bci exp, ortho, pred G GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP G GP GP G SOCS1 AXL 12470648, 23023127 hprd,i2d exp, ortho, pred GP G P GP GP GP GP GP G G GP P G GP G GP GP P GP G GP GP G SOCS1 CUL2 19327355, 25402006 intact exp, ortho, pred GP GP P G GP GP GP GP GP G G P GP GP G GP P GP G G GP GP G SOCS1 TEC 9341160, 25402006 hprd,biogrid,bci exp, ortho, pred P P P P P P P P P P P P P P P P P P P SOCS1 CSF1R 10022833,11297560, 25402006, 21836163 hprd,biogrid,i2d exp, ortho, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 IFNAR1 21757742, 16082366 biogrid,bci exp, ortho, pred GP GP P P GP P GP GP GP GP G GP P GP GP G GP P GP P GP GP SOCS1 TRIM8 12163497, 25402006, 21836163 hprd exp, ortho, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 PIM2 11854514, 25402006 hprd,bci exp, ortho, pred G G P GP GP G G GP G G GP P G G G GP P G GP G GP GP G SOCS1 TCEB1 22787435,21119685,17183367,10051596,16643902, 25402006 hprd,biogrid,mint,intact,bci exp, ortho, pred G G G G G G G G G G G G G G G G G G G G SOCS1 JAK1 10707961,11133764, 25402006, 23023127 hprd,biogrid,bci exp, ortho, pred GP GP P P GP GP GP GP GP GP G GP P G GP G GP P GP P GP G GP GP G SOCS2 SOCS1 17898043, 25402006, 23023127 biogrid exp, ortho, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 JAK2 18508766,9202126,10455112,11314018,19287004,10421843,14522994,11971965,11713228,10064597,9344848, 25402006, 23023127, 21836163 innatedb,hprd,biogrid,mint,intact,bci exp, ortho, pred G GP P P GP GP GP P GP GP G P P GP P P GP GP GP GP GP SOCS1 MET 24728074, 23023127 intact exp, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 STAT4 16082366 bci exp, pred G GP P P G GP GP GP GP GP G GP P G GP G GP P G GP GP GP GP G SOCS1 COMMD1 17183367, 25402006 hprd,biogrid,mint,intact exp, pred GP GP P P GP GP GP GP GP GP G GP P G GP G GP P GP P GP GP GP GP G SOCS1 FLT3 10022833, 25402006, 23023127, 21836163 hprd,biogrid,i2d,bci exp, pred GP P P P GP GP GP GP P GP P P GP GP G GP P GP P GP P P GP G SOCS1 SOCS5 25402006, 23023127 bci exp, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP G GP GP G SOCS1 TCEB2 21119685,10051596, 25402006, 21836163 hprd,biogrid,bci exp, pred G G G G G G G G G G G G G G G G G G G G SOCS1 RASA1 18556463, 25402006, 23023127 innatedb,biogrid exp, pred GP G P P G G G G G G G G P G G G GP G G G GP G G SOCS1 CSF2RB 24086733, 21836163 biogrid,bci exp, pred GP P P P GP GP P GP GP GP G GP P GP GP G GP P GP P GP GP GP P G SOCS1 STAT3 25402006, 16082366 bci exp, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 IRS2 12228220, 25402006, 21836163 hprd,biogrid,bci exp, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 ITK 10022833, 25402006, 23023127, 21836163 hprd,biogrid,i2d,bci exp, pred G G G G G G G G G G G G G G G G G SOCS1 CSF1 11297560, 25402006 hprd exp, pred G G G G G G G G G G G G G G G G G G G G SOCS1 JAK3 11133764, 25402006, 23023127 hprd,bci exp, pred G G G G G G G G G G G G G G G G G G G G SOCS1 FYN 10022833, 25402006, 23023127, 21836163 hprd,biogrid,i2d,bci exp, pred G GP P P G GP GP GP G GP G G P G G G G G G GP G G G SOCS1 NCK1 10022833, 25402006, 23023127, 21836163 hprd,biogrid,i2d,bci exp, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP GP GP GP GP G SOCS1 PTPN11 14522994, 25402006 biogrid exp, pred GP GP P G GP GP GP GP GP G GP P GP GP G GP P GP GP GP GP GP G SOCS1 ABL1 22787435, 25402006, 23023127 biogrid exp, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 NEDD9 23023127 bci exp, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 CRK 10022833,25814554, 25402006 biogrid,intact exp, pred GP G GP GP GP GP G G G GP G GP G GP P GP P GP G GP G G SOCS1 STAT5B 25402006 bci exp, pred GP GP P P GP GP GP GP GP GP G GP P G G G GP P GP GP GP GP GP G SOCS1 IGF1R 9727029, 25402006, 23023127 hprd,biogrid,i2d,bci exp, pred GP GP GP GP GP GP GP GP G GP G GP G GP P GP GP GP GP GP G SOCS1 IRS1 17276034,12228220,11208867, 25402006, 23023127 hprd,biogrid,bci exp, pred GP GP P P G GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP P G SOCS1 VAV2 10022833, 25402006, 23023127, 21836163 hprd,biogrid,bci exp, pred GP GP P P G GP GP GP GP G G GP P GP GP G GP P GP GP GP GP GP G SOCS1 FGFR3 16410555, 23023127 biogrid exp, pred G P P P GP G GP G GP P G G GP GP G G GP SOCS1 PDGFRB 10022833, 25402006 hprd,i2d,bci exp, pred G G P G G GP G G G G G P GP G G GP P G G G GP GP G PIK3R2 SOCS1 10022833, 25402006, 23023127, 21836163 hprd,i2d,bci exp, pred G G G G G G G G G G G G G G G G G G G G SOCS1 CRKL 25814554, 25402006, 23023127 biogrid,intact exp, pred GP G P P G GP G G GP GP G GP P G GP G GP P G GP GP GP G G SOCS1 MAP3K5 19287004,18776134,16407264, 25402006 innatedb,biogrid,mint,intact exp, pred G GP P P G GP GP G GP GP G G P GP GP G G P G G GP GP GP G SOCS1 LCK 21234523, 23023127 biogrid exp, pred G P G G G G G GP G G G G GP G SOCS1 GRB2 10022833, 25402006, 23023127 hprd,biogrid,i2d,bci exp, pred GP GP P P G GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 MPL 10517496, 25402006, 21836163 hprd,biogrid exp, pred P P P P P P P P P P P P P P P SOCS1 GHR 10585430, 25402006 hprd,biogrid exp, pred G G G G G G G G G G G G G G G G G G SOCS1 STAT5A 25402006 bci exp, pred G GP P G GP GP GP GP GP G G GP GP G GP G G GP G G G SOCS1 ALK 14968112, 25402006 biogrid exp, pred GP GP P P GP GP P G GP GP G GP P GP GP G GP P GP P GP P GP GP G SOCS1 SOCS1 14968112, 23023127 intact exp, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 PIK3R1 10022833,25814554, 25402006, 23023127, 21836163 hprd,biogrid,intact,bci exp, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 BCLAF1 ortho GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 UBC ortho GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 CUL5 ortho GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 NT5C2 ortho G GP P P GP GP GP GP GP G G GP P GP G G GP P GP P GP GP GP GP G SOCS1 PSMC6 ortho GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 TRIM28 ortho GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 PCSK4 ortho GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP P GP GP G SOCS1 PAG1 ortho GP G P P GP GP G GP GP GP G GP P G GP G GP GP GP GP GP P G SOCS1 HMGXB3 ortho G G P P G G G G GP GP G G P G GP G GP G G G G G G SOCS1 PTK2B 25402006, 23023127 ortho, pred GP GP P GP GP GP G GP GP G GP P G GP G P P G GP G GP GP G SOCS1 PIM1 25402006 ortho, pred G GP P P G GP GP GP G G G GP P G G G G P G P GP G GP GP G SOCS1 SHC1 25402006, 23023127 ortho, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 CREBBP 25402006 ortho, pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 STXBP4 23023127 pred P GP P P P P GP P P P G P P GP GP G GP P P P GP P P P G SOCS1 GAB1 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G SOCS1 TGFBR1 23023127 pred GP G P P GP GP GP GP GP G G GP P G G G G G GP G GP G G SOCS1 GNB2L1 25402006 pred P P P P P P P P P P P P P P P P P P SOCS1 EPOR 25402006 pred G G G G G G G G G G G G G G G G G G G G ARHGEF37 SOCS1 23023127 pred GP GP P GP GP GP G G G G GP P G P G GP GP GP G GP GP G SOCS1 HMGA2 25402006 pred GP GP P P GP GP GP GP P P GP P GP GP G GP P GP P GP P GP GP G SOCS1 SH3GL2 25402006 pred P G P GP G G SOCS1 SYK 25402006, 23023127 pred GP G P P GP GP G GP GP G GP P GP G G G GP GP GP GP G SOCS1 PTPRJ 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 NFKB2 25402006 pred GP GP P P G GP GP G GP GP G GP P G GP G GP GP GP GP GP GP G SOCS1 APPL1 23023127 pred GP GP P P G GP GP G GP GP G GP P GP GP G GP P GP GP GP GP GP G SOCS1 IFI6 25402006 pred GP GP P GP GP GP GP GP GP G GP P GP GP G GP P GP GP GP GP GP G SOCS1 OXT 23023127 pred G G SOCS1 TRIB3 25402006 pred GP GP P P G GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 COMMD3 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 PARP1 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 AES 25402006 pred G G G G G G G G G G G G G G G G G G G G SH2D7 SOCS1 23023127 pred P P P P P P P P P SOCS1 FGFR1 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 TSHB 23023127 pred G G G G G G G G G G G G G G G G G G G SOCS1 IRF2 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 BMP7 23023127 pred G G G G G G G G G G G G G G G G G SOCS1 SH2D4B 23023127 pred P P P GP P P P P P GP P G P P GP P P P P P G SOCS1 FASLG 23023127 pred P GP P P G GP GP G P G P P GP GP G GP P GP P P GP P GP G SOCS1 SOCS4 25402006, 23023127 pred GP GP P P G GP GP G GP GP G GP P G G G GP P GP P GP GP GP GP G SOCS1 MAP3K9 23023127 pred P GP P P GP GP GP P G G GP P P GP G GP P GP P GP GP GP GP G TRAF5 SOCS1 25402006 pred GP GP P P GP GP GP GP GP GP G GP P G GP G GP P GP P GP GP GP GP G SOCS1 AKT2 23023127 pred GP GP P P G GP GP GP GP GP G GP P GP GP G GP P GP GP GP GP GP G SOCS1 ROBO1 23023127 pred GP GP P P GP GP GP P GP GP G GP P GP P G P P GP P GP GP GP GP G SOCS1 SRC 25402006, 23023127 pred GP GP P GP G GP G G G G GP P G G G P GP GP GP GP GP G SOCS1 MAP2K3 25402006 pred P P P P P P P P P P P P P P P P P P P P P SOCS1 SH2D2A 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G SOCS1 PRL 23023127 pred G G G G G G G G G G G G G G G G SOCS1 LYN 25402006, 23023127 pred GP G P P G GP G G GP GP G GP P G GP G GP P GP GP GP GP G G SOCS1 AKT1 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 CTNNB1 25402006 pred GP GP P P GP GP GP GP GP G G GP P GP GP G GP P GP GP G GP GP G CHUK SOCS1 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 SH2D3A 25402006 pred GP GP P P GP GP GP GP GP G G GP P G GP G GP P GP P GP GP GP GP G SOCS1 PTPN6 25402006 pred G G P G G G G GP GP G G G G G GP G G GP G G G SOCS1 YES1 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP G GP GP G SOCS6 SOCS1 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP P GP GP G SOCS1 BLK 23023127 pred GP P P P P P P P GP P P P P P GP P P SOCS1 SHB 23023127 pred GP GP P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 PIK3R3 25402006, 23023127 pred GP GP P P G GP GP GP GP GP G GP P G GP G GP GP GP GP GP GP G SOCS1 PTK2 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 PRKCZ 23023127 pred G GP P GP GP GP GP GP GP G GP P GP G GP P GP P GP GP GP GP SOCS1 TXNDC17 23023127 pred GP GP P GP GP GP G GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 FLT1 23023127 pred G G P GP GP G G G G G G P G G G GP G P G G G G G SOCS1 CUL1 25402006 pred GP G P GP GP GP GP GP G G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 TNK2 25402006, 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 NTRK1 23023127 pred P P P P P P P P P P P P P P P P P P SOCS1 UBASH3A 23023127 pred P P G P P P G SOCS1 RALGDS 16082366 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 NCK2 25402006, 23023127 pred G GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 ZAP70 23023127 pred G P G G G GP G G GP G SOCS1 CTNNA1 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 EPS8 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 PLG 23023127 pred P P G G P P P P SOCS1 EPS8L3 23023127 pred G G P P GP GP P G GP G G GP P GP GP G G G P GP G GP G SOCS1 ARHGEF9 23023127 pred GP GP P P GP GP GP GP G G G G P G GP G GP GP P G GP G P G SOCS1 RALGPS2 16082366 pred GP GP P P P GP GP GP P GP G GP P GP P P P P GP GP GP GP SOCS1 PRKCA 25402006, 23023127 pred G GP P P GP GP GP G G GP G GP P G GP G GP G P GP G GP GP G SOCS1 IGFBP1 23023127 pred GP G G G GP G SOCS1 STAT6 21836163 pred GP GP P P G GP GP G GP GP G GP P GP G G GP P GP GP GP GP GP G SOCS1 ABI2 23023127 pred G G G G G G G G G G G G G G G G G G G G SOCS1 GRAP2 23023127 pred P P P P P P P P P P P P P P P SOCS1 CSF2RA 21836163 pred GP P P P P P P P P P P GP P P P SOCS1 TLN1 25402006 pred GP GP P P G GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 CXCL8 25402006 pred G GP P P GP GP G G GP G G P GP G G G G P G GP GP P G SOCS1 LIFR 21836163 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 GRB10 25402006, 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 IGSF10 23023127 pred GP GP P P GP GP P P GP GP G P P GP P G P P GP P GP GP GP INPPL1 SOCS1 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 BTK 25402006, 23023127 pred G P G GP GP G G GP G SOCS1 MAPK8IP1 25402006, 23023127 pred P P P P P P P P P P P P P G P P P P P P P GP SOCS1 MAPK8IP2 25402006, 23023127 pred G GP P P GP GP GP GP GP GP G GP P G GP G GP P GP P GP GP GP GP G SOCS1 EIF2AK2 25402006 pred GP GP P P G GP GP G GP GP G GP P G GP G GP P GP GP G GP GP G SOCS1 CALM1, CALM2, CALM3 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 THBD 23023127 pred GP G G GP G G G G G G G GP G GP G G G G G G SOCS1 PRKACA 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 RASGEF1C 16082366 pred P P P P P P P P P P P P P GP P P P P P P GP SOCS1 BCL2 25402006 pred G G P P G GP GP G G GP G G P GP G G GP P G G GP G G G SOCS1 SH2D3C 23023127, 16082366 pred GP G P GP G GP G G GP G G G G GP G G GP GP GP G SOCS1 BCAR1 25402006, 23023127 pred GP GP P P GP GP GP GP GP GP GP P GP GP G GP P GP P GP GP GP GP G SOCS1 CX3CL1 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 IL12RB1 23023127, 21836163 pred G G G G G G SOCS1 ARHGEF12 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 FGR 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G P P GP GP GP GP P G SOCS1 CISH 25402006, 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 TYRO3 25402006 pred G G G G G G G G G G G G G G G G G G G G SOCS1 MAP2K4 25402006 pred GP GP P P G GP GP G GP G G G P G G G GP G G G GP GP G SOCS3 SOCS1 25402006, 23023127 pred GP GP P P GP GP GP GP GP G G GP P GP GP G GP GP P GP G GP GP G SOCS1 ARNT2 23023127 pred P P P GP G GP G G P G G G P G G G GP G SOCS1 SLA2 25402006, 23023127 pred G G G G G G G G G G G G G G SOCS1 CCL2 23023127, 16082366 pred GP GP P P G GP GP GP GP GP G GP P GP GP G GP P P GP GP GP P G SOCS1 PPP5C 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 GHRHR 23023127 pred G G G G G G G G G SOCS1 STAT1 25402006, 21836163, 16082366 pred G G P P G GP GP G GP GP G GP P G GP G GP P G GP GP G GP G SOCS1 IGFBP7 23023127 pred G G G G GP G G G G G G GP G G G G G G GP G SOCS1 Fos39347_1 25402006 pred SOCS1 PTPN18 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP GP P GP GP GP GP G SOCS1 SPRED2 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GP P GP GP GP GP GP G G GP P GP GP G GP P GP P GP G GP GP G SOCS1 SH3GLB2 23023127 pred G GP P G GP GP G GP G G P G GP G GP G G GP GP GP G SOCS1 TSC2 23023127 pred G GP P GP GP GP GP GP G G GP P GP GP G GP G GP G GP GP G SOCS1 SORBS1 23023127 pred GP GP P P GP GP GP GP GP G G GP P GP GP G GP P GP P GP G GP GP G SOCS1 ERBB3 25402006 pred GP GP P P GP GP GP GP GP GP G GP P P GP G GP P GP P GP P GP GP G SOCS1 DAXX 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 IKZF1 23023127 pred G G P G G G G GP G G G G G G G G GP G G G SOCS1 CDC25A 25402006 pred P P P P P P P P P P P P P P P P P P GP SOCS1 NOTCH1 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 COMMD6 25402006 pred G GP P G G G G G G G G P G GP G G G G G G G G SOCS1 EGF 25402006, 23023127 pred P P P P GP P GP P P P G P P GP P P GP P GP P P P SOCS1 GNA12 25402006 pred GP GP P P G GP GP GP GP GP G GP P G GP G GP P GP P GP G GP GP G SOCS1 TXK 23023127 pred P P G G G G P G SOCS1 ERBB4 25402006, 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP P GP GP G SOCS1 ANKS1A 25402006 pred GP GP P G GP GP GP GP GP G GP G GP G GP P GP GP GP GP GP G SOCS1 PARK2 23023127 pred P GP P P GP GP GP P P G P P GP P G P GP P GP P GP G SOCS1 MAP3K2 25402006 pred G GP P GP GP GP GP G G G GP P G G G GP P GP P GP G GP GP G SOCS1 TG 23023127 pred G G G G G G G G G G G G G G G G G G G SOCS1 EP300 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 KHDRBS1 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 CSNK2A2 25402006 pred G G G G G G G G G G G G G G G G G G G G SOCS1 VRK3 23023127 pred GP GP P P GP GP GP GP GP GP G GP P G GP G GP P GP P GP GP GP GP G SH3PXD2B SOCS1 23023127 pred GP GP P G GP GP G GP G G G P GP GP G GP P GP G G GP GP G SOCS1 PHB2 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 MED8 25402006 pred GP GP P P GP GP GP GP GP GP 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SOCS1 SH2B1 25402006 pred G G G G G G G G G G G G G G G G G G G G IKBKB SOCS1 25402006 pred GP GP P P G GP GP G GP GP G GP P GP GP G GP P GP GP GP GP GP G SOCS1 PDGFRA 25402006, 23023127 pred G G P P G G GP G G G G G P GP G G GP G G G GP G G SOCS1 PLAU 23023127 pred G G P P G GP GP GP GP G GP P GP GP G GP P G GP GP GP GP G SOCS1 PICK1 25402006 pred GP GP P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP G GP GP G SOCS1 CAMK2G 25402006 pred G GP P GP GP GP G G GP G GP P G GP G GP P GP P GP G GP GP G RASGRF2 SOCS1 16082366 pred GP GP P P GP GP GP P GP GP G GP P GP GP G GP P P P GP GP GP GP G SOCS1 MIA2 23023127 pred P P P P GP GP P P G GP P P P P P P G SOCS1 GATA4 23023127 pred P P P P GP P P GP P P GP P GP GP GP P P P GP P GP GP SOCS1 MASP1 23023127 pred G GP GP G G GP GP G G G G G G G G G G GP G SOCS1 XIAP 25402006 pred GP GP P GP GP GP GP GP GP G GP P G GP G G P GP GP G GP GP G SOCS1 VCAM1 25402006 pred G G G G GP G G GP G G G G G G G G GP G GP G SOCS1 CD80 23023127 pred G G P P G G G G G GP G G P G G G GP G G GP G G G SOCS1 TUBA1A 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 GRB7 25402006, 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP P GP GP G SOCS1 CIITA 25402006 pred GP GP P G GP GP G GP GP G GP P G G G P GP P GP GP GP G G SOCS1 IL12RB2 25402006 pred P P P P P P P P P P P P P P GP P GP P P SOCS1 TRIP6 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 DOK2 25402006 pred G G P G G G GP GP G G G G G G G GP G G SOCS1 ARHGEF19 23023127 pred G G G G G G G G G G G SOCS1 RELB 25402006 pred GP GP P GP GP GP GP GP GP G GP P G G G G G GP GP GP GP G SOCS1 WSB1 21836163 pred GP GP P G GP GP GP G G G GP P G GP G GP P G GP G GP GP G SOCS1 KLK6 23023127 pred G G G G G G G G G G G G G G G G G G G G SOCS1 GRAP 23023127 pred P P P GP P GP GP G P GP P P P P P GP P P SOCS1 GTF2B 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 HCK 23023127 pred 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GP GP G GP G G G SOCS1 RAPGEF3 16082366 pred GP P P P GP GP GP P GP GP G P P G GP GP P GP P P GP GP P G SOCS1 MUC1 25402006 pred GP P GP GP P GP P G GP GP GP P GP GP GP GP G SOCS1 SHC4 23023127 pred G G G G SOCS1 TNN 16082366 pred GP G P G GP P GP GP G G GP P GP GP G P P G P GP GP GP P G SOCS1 STAP1 25402006, 23023127 pred P P P P GP GP P GP P P P P P GP GP P SH2B2 SOCS1 25402006, 23023127 pred GP GP P P G GP GP GP GP G G GP P G GP G GP P GP GP GP GP GP G SOCS1 ABI3 23023127 pred G G P P GP GP GP G GP GP G GP P G G G G P GP GP G G SOCS1 SLC25A6 25402006 pred G GP P P G G GP GP G G G GP P G GP G G GP GP G GP GP G SOCS1 SCNN1D 25402006 pred P P P P P P G P P P P P P G P P P P P P GP G SOCS1 HPX 23023127 pred G GP GP G GP GP GP G G G G G G G GP GP G SOCS1 BCAR3 25402006, 23023127, 16082366 pred GP GP P P GP GP GP GP GP GP G GP P G P G GP P GP P GP G GP GP G SOCS1 PTK6 25402006, 23023127 pred GP GP P P P GP P P GP G GP P P P G P P GP P GP GP GP P SOCS1 HSP90AA1 25402006 pred GP GP P G GP G G G G G G P G G G GP G G G G GP G SOCS7 SOCS1 23023127 pred G G G G G G G G G G G G G G G G G G G G SOCS1 PIK3CA 25402006, 23023127 pred GP GP P P GP GP GP GP GP GP G P P GP GP G P P GP P GP GP GP GP SOCS1 CXCL10 25402006 pred G G G G G G G G G G G G G G G G G G G G IRS4 SOCS1 25402006 pred GP GP P GP GP GP P P GP G GP P G GP G GP P GP P GP GP GP GP G SOCS1 LRRC41 25402006, 21836163 pred G G P GP GP GP G GP GP G GP G GP G GP G P GP G GP GP G SOCS1 BMX 23023127 pred GP P P P GP GP P P P G GP P GP P P P GP P P SOCS1 PLCG1 25402006, 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 DNMBP 23023127 pred GP GP P GP GP G G GP G G G P GP G G GP P G P G G GP G G SOCS1 THBS1 23023127 pred GP GP P P GP GP GP G GP GP G GP P GP GP G GP GP P GP GP GP P G SOCS1 CDH1 25402006 pred GP GP GP GP GP G G GP GP G GP P GP GP G GP G SOCS1 IL2RA 21836163 pred G G P G G G G GP G G G G G G P G G SOCS1 NGEF 23023127 pred P GP P P P GP GP GP P GP G GP P G GP P P P P GP P GP GP G SOCS1 STUB1 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 CTSG 23023127 pred G G P G G G G GP G G G G G G G P G G G SMAD7 SOCS1 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP P G SOCS1 ESR1 25402006 pred GP G G G G G G G G G G G G G G G G G G G SOCS1 INPP5D 23023127 pred G GP P P GP G GP G G GP G G P GP G G G GP P G GP G G G SOCS1 BAZ2A 21836163 pred G GP P G GP GP G GP G G G P G GP G GP G P G G GP GP G SOCS1 ADIPOQ 23023127 pred GP G GP GP P G G G P G G P G G SOCS1 SOS1 16082366 pred GP G P GP GP GP G GP GP G GP G GP G GP P GP P GP GP GP G G SOCS1 DLC1 23023127 pred G G P G GP GP G G G G GP P G G G G G GP G G GP G SOCS1 TRIO 23023127 pred GP GP P G GP GP GP GP GP G GP P GP GP G GP P GP GP GP GP GP G SOCS1 PSEN2 23023127 pred G G G G G G G G G G G G G G G G G G G SOCS1 F10 23023127 pred G G G G G G G G G G G G G G G G G SOCS1 TMPRSS6 23023127 pred G G G G G G G G G G G G G G G G G G G SOCS1 CDK5RAP3 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 FER 25402006, 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 CCR5 25402006 pred G G G G G G G G G G G G G G G G G G G SOCS1 NCOA3 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 SH2D6 23023127 pred P P P GP P GP GP P G GP P G G P P P P GP SOCS1 PRSS8 23023127 pred G P P GP G G G G G P G G GP P GP P G G GP G SOCS1 FGD4 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP GP GP GP GP G SOCS1 NF2 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 EGR1 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 CASP8 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP P G GP P GP P GP GP GP GP G SOCS1 ZMAT3 23023127 pred G G G G G G G G G G G G G G G G G G G G SOCS1 RIN1 25402006 pred GP GP P P GP GP GP GP GP G G GP P GP GP G GP P GP P GP G GP GP G SOCS1 MYO1E 23023127 pred GP P P P GP GP GP GP GP GP G GP P G GP G GP P G GP G GP GP G SOCS1 FLT4 25402006 pred G G G G G G G G G G G G G G G SOCS1 PF4 23023127 pred G G P G G G G G G G G G G G G G SOCS1 ITSN2 23023127 pred G G P G GP GP GP G G G GP P G GP G GP P G GP G GP GP G SOCS1 IRF7 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 PXN 25402006 pred GP GP P P G GP GP G GP GP G GP P GP GP G GP P GP GP GP G GP G SOCS1 SOS2 16082366 pred GP GP P P GP GP GP G GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 SHC2 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 PLEKHA1 23023127 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 IL12B 16082366 pred P P P P P P P P P P P P P SOCS1 LDLR 23023127 pred G GP P GP GP GP GP GP G G GP P G G G GP G P GP G GP GP G SOCS1 ITSN1 23023127 pred G GP P GP GP GP GP GP GP G GP P G G G GP GP P GP G GP GP G SOCS1 SRMS 25402006, 23023127 pred P P P P P P P P P P P P P P P P P P P P P P SOCS1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P SOCS1 MAP3K3 25402006 pred G G P P GP G GP G GP GP G GP P G G G GP G GP GP GP G G PIK3C2B SOCS1 25402006 pred GP G G GP GP GP GP G G GP G GP G GP P GP GP G GP G G SOCS1 PACSIN3 23023127 pred GP GP P GP P P GP P G G GP P GP GP GP P GP P GP GP P G SOCS1 PTPN2 25402006 pred GP GP P P GP GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 TNFRSF14 23023127 pred GP GP P GP GP GP GP GP GP G GP G GP G G P GP GP GP GP GP G SOCS1 PLCG2 25402006, 23023127 pred G GP P P GP GP GP G GP GP G GP P GP G G GP G P GP GP GP GP G SOCS1 RAPGEF1 16082366 pred G GP P P G GP GP G GP GP G GP P G GP G GP P G P GP GP GP GP G SOCS1 RAPGEFL1 16082366 pred G P P P P P GP P P P P P P P SOCS1 CEBPB 25402006 pred GP GP P P G GP GP GP GP GP G GP P GP GP G GP P GP P GP GP GP GP G SOCS1 BAIAP2 23023127 pred P P P P GP P GP GP GP GP P P GP GP G GP P P P P P GP GP G SOCS1 CLK4 23023127 pred GP GP P GP GP GP GP GP G G GP P G GP G GP P GP P GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O15524 - 12470648 - X 2 P52735-3 O15524 - 10022833 - X 2 O15524 - 10022833 - X 2 O15524 - 11342531 - X 2 P08069 O15524 - 8776723,9727029 - X 2 O15524 - 10022833 - X 2 P16333 O15524 - 10022833 - X 2 P06241 O15524 - 10022833 - X 2 A0A024RDA0 O15524 - 10022833 - X 2 O15524 P07333 - 10022833 - X 2 O15524 P15498 - 10022833 - X 2 B0LPF3 O15524 - 10022833 - X 2 O15524 - 10022833 - X 2 Q08881 O15524 - 10022833 - X 2 P09619 O15524 - 10022833 - X 2 P17181 O15524 affinity chromatography technology 21757742 physical association X 2 P40238 O15524 affinity chromatography technology 10517496 physical association X 2 P08069 O15524 two hybrid 9727029 direct interaction X 2 P0CG48 O15524 affinity chromatography technology 17898043 physical association X 2 O15524 Q9BXN2-10 affinity chromatography technology 21899704 physical association X 2 O15524 Q04206 affinity chromatography technology 14690596 physical association X 2 O15524 Q04206 affinity chromatography technology 14690596 physical association X 2 O15524 Q04206 affinity chromatography technology 14690596 physical association X 2 O15524 affinity chromatography technology 16415872 physical association X 2 O15524 A0A024R499 affinity chromatography technology 17276034 physical association X 2 O15524 P20936-4 affinity chromatography technology 18556463 physical association X 2 O15524 P20936-4 affinity chromatography technology 18556463 physical association X 2 O15524 P23458 affinity chromatography technology 10707961 physical association X 2 O15524 affinity chromatography technology 21234523 physical association X 2 O15524 affinity chromatography technology 21234523 physical association X 2 O15524 affinity chromatography technology 11342531 physical association X 2 O15524 P04637-7 affinity chromatography technology 20005840 physical association X 2 O15524 P04637-7 pull down 20005840 direct interaction X 2 O15524 P04637-7 affinity chromatography technology 20005840 physical association X 2 O15524 P04626-3 unspecified method 16273093 direct interaction X 2 O15524 Q15369-2 affinity chromatography technology 22787435 physical association X 2 O15524 Q59FK4 affinity chromatography technology 22787435 physical association X 2 O15524 A0A024R499 affinity chromatography technology 12228220 physical association X 2 O15524 P10721-2 two hybrid 10022833 direct interaction X 2 O15524 P10721-2 affinity chromatography technology 10022833 physical association X 2 O15524 P62993-2 pull down 10022833 direct interaction X 2 O15524 L7RT18 pull down 10022833 direct interaction X 2 O15524 P06241-3 pull down 10022833 direct interaction X 2 O15524 P10912-2 affinity chromatography technology 10585430 physical association X 2 O15524 P10912-2 pull down 10585430 direct interaction X 2 O15524 Q15369-2 affinity chromatography technology 10051596 physical association X 2 O15524 P14784 affinity chromatography technology 11133764 physical association X 2 O15524 P00533 affinity chromatography technology 12070153 physical association X 2 O15524 A0A024RBD2 affinity chromatography technology 17898043 physical association X 2 O15524 Q04206 pull down 17183367 direct interaction X 2 O15524 Q04206 pull down 17183367 direct interaction X 2 O15524 Q15370-2 affinity chromatography technology 21119685 physical association X 2 O15524 Q15369-2 affinity chromatography technology 21119685 physical association X 2 O15524 E2GIM6 affinity chromatography technology 21079688 physical association X 2 O15524 E2GIM6 affinity chromatography technology 21079688 physical association X 2 O15524 Q04206 affinity chromatography technology 21084693 physical association X 2 O15524 Q04206 affinity chromatography technology 21084693 physical association X 2 Q99683 O15524 affinity chromatography technology 18776134 physical association X 2 Q99683 O15524 affinity chromatography technology 18776134 physical association X 2 Q99683 O15524 affinity chromatography technology 16407264 physical association X 2 Q99683 O15524 affinity chromatography technology 16407264 physical association X 2 Q99683 O15524 pull down 16407264 direct interaction X 2 P23258 O15524 biochemical 15456882 association X 2 A0A024R7E4 O15524 affinity chromatography technology 21757742 physical association X 2 P36888 O15524 affinity chromatography technology 10022833 physical association X 2 Q15116 O15524 affinity chromatography technology 21263070 physical association X 2 P32927 O15524 affinity chromatography technology 24086733 physical association X 2 P16333 O15524 pull down 10022833 direct interaction X 2 P40337-3 O15524 affinity chromatography technology 21685897 physical association X 2 P40337-3 O15524 affinity chromatography technology 21685897 physical association X 2 Q14241 O15524 affinity chromatography technology 10051596 physical association X 2 Q9Y4H2 O15524 affinity chromatography technology 12228220 physical association X 2 Q9Y4H2 O15524 affinity chromatography technology 12228220 physical association X 2 Q06124-2 O15524 affinity chromatography technology 14522994 physical association X 2 O60759 O15524 affinity chromatography technology 23469018 physical association X 2 O60759 O15524 two hybrid 23469018 direct interaction X 2 O15524 P15498 affinity chromatography technology 10747851 physical association X 2 O15524 O75553-6 affinity chromatography technology 17974915 physical association X 2 O15524 P41212 affinity chromatography technology 11314018 physical association X 2 O15524 O60674 affinity chromatography technology 11314018 physical association X 2 O15524 P41212 affinity chromatography technology 11314018 physical association X 2 O15524 O60674 affinity chromatography technology 11314018 physical association X 2 O15524 O60674 affinity chromatography technology 18508766 physical association X 2 O15524 affinity chromatography technology 16410555 physical association X 2 O15524 O60674 affinity chromatography technology 19287004 physical association X 2 O15524 A0A024R3C7 affinity chromatography technology 20005840 physical association X 2 O15524 Q13535 affinity chromatography technology 20005840 physical association X 2 O15524 A0A024R3C7 pull down 20005840 direct interaction X 2 O15524 Q77YG1 affinity chromatography technology 18172216 physical association X 2 O15524 Q77YG1 affinity chromatography technology 18172216 physical association X 2 O15524 Q77YG1 pull down 18172216 direct interaction X 2 O15524 Q77YG1 pull down 18172216 direct interaction X 2 O15524 O60674 two hybrid 10064597 direct interaction X 2 O15524 O60674 affinity chromatography technology 11713228 physical association X 2 O15524 P15498 affinity chromatography technology 10022833 physical association X 2 O15524 P52735 affinity chromatography technology 10022833 physical association X 2 O15524 O60674 two hybrid 9202126 direct interaction X 2 O15524 O60674 pull down 9202126 direct interaction X 2 O15524 O60674 affinity chromatography technology 9202126 physical association X 2 O15524 P42680 pull down 9341160 direct interaction X 2 O15524 P42680 two hybrid 9341160 direct interaction X 2 O15524 O60674 pull down 10064597 direct interaction X 2 O15524 O60674 affinity chromatography technology 10064597 physical association X 2 O15524 P07333 affinity chromatography technology 11297560 physical association X 2 O15524 P07333 pull down 11297560 direct interaction X 2 O15524 O60674 affinity chromatography technology 10455112 physical association X 2 O15524 O60674 affinity chromatography technology 11971965 physical association X 2 O15524 O60674 pull down 9344848 direct interaction X 2 O15524 P07333 two hybrid 11297560 direct interaction X 2 O15524 Q8N668 affinity chromatography technology 17183367 physical association X 2 O15524 Q8N668 pull down 17183367 direct interaction X 2 O15524 Q77YG1 biochemical 19327355 colocalization X 2 O15524 Q77YG1 biochemical 19327355 association X 2 O15524 O60674 affinity chromatography technology 14522994 physical association X 2 Q9UM73 O15524 affinity chromatography technology 14968112 physical association X 2 Q08881 O15524 pull down 10022833 direct interaction X 2 O15524 Q77YG1 pull down 18172216 physical association X 2 O15524 Q77YG1 anti tag coimmunoprecipitation 18172216 physical association X 2 O15524 Q77YG1 anti tag coimmunoprecipitation 18172216 physical association X 2 O15524 Q77YG1 anti tag coimmunoprecipitation 18172216 physical association X 2 O15524 Q77YG1 pull down 18172216 physical association X 2 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 O15524 in vivo 11384984 - C 9 P10912 O15524 in vivo 10585430 - X 2 P10912 O15524 in vivo 10585430 - X 2 Q9BZR9 O15524 in vivo 12163497 - X 2 Q9BZR9 O15524 in vivo 12163497 - X 2 O15524 two hybrid 12470648 - X 2 O15524 two hybrid 12470648 - X 2 A0A024QYW7 O15524 in vitro 11854514 - X 2 A0A024QYW7 O15524 in vitro 11854514 - X 2 P52735-3 O15524 in vivo 10022833 - X 2 P52735-3 O15524 in vivo 10022833 - X 2 O15524 in vitro 10022833 - X 2 O15524 in vitro 10022833 - X 2 P40238 O15524 in vitro 10517496 - X 2 P40238 O15524 in vitro 10517496 - X 2 P08069 O15524 two hybrid 9727029 - X 2 P08069 O15524 in vivo 9727029 - X 2 P08069 O15524 two hybrid 9727029 - X 2 P08069 O15524 in vivo 9727029 - X 2 O15524 P15260 in vivo 15522878 - X 2 O15524 P62993-2 in vivo 10022833 - X 2 O15524 P00533 in vivo 12070153 - X 2 O15524 in vitro 10022833 - X 2 O15524 P14784 in vivo 11133764 - X 2 O15524 A0A024R499 in vivo 11208867,12228220 - X 2 O15524 A0A024R499 in vitro 11208867,12228220 - X 2 O15524 two hybrid 15169905 - X 2 O15524 in vitro 15169905 - X 2 O15524 P23458 in vitro 11133764 - X 2 O15524 P10721-2 in vivo 10022833 - X 2 O15524 P27986 in vitro 10022833 - X 2 O15524 A0A024R7M7 in vitro 11133764 - X 2 O15524 Q15370-2 in vivo 10051596 - X 2 O15524 Q15370-2 in vitro 10051596 - X 2 O15524 Q15369-2 in vitro 10051596 - X 2 O15524 Q15369-2 in vivo 10051596 - X 2 O15524 A0A024R7M7 in vitro 11133764 - X 2 O15524 Q15370-2 in vivo 10051596 - X 2 O15524 Q15370-2 in vitro 10051596 - X 2 O15524 Q15369-2 in vivo 10051596 - X 2 O15524 Q15369-2 in vitro 10051596 - X 2 O15524 P10721-2 in vivo 10022833 - X 2 O15524 P15260 in vivo 15522878 - X 2 O15524 P27986 in vitro 10022833 - X 2 O15524 P00533 in vivo 12070153 - X 2 O15524 in vitro 10022833 - X 2 O15524 P14784 in vivo 11133764 - X 2 O15524 A0A024R499 in vitro 11208867,12228220 - X 2 O15524 A0A024R499 in vivo 11208867,12228220 - X 2 O15524 two hybrid 15169905 - X 2 O15524 in vitro 15169905 - X 2 O15524 P23458 in vitro 11133764 - X 2 O15524 P62993-2 in vivo 10022833 - X 2 P36888 O15524 in vivo 10022833 - X 2 P36888 O15524 in vivo 10022833 - X 2 A0A024R3M4 O15524 in vivo 16415872 - X 2 A0A024R3M4 O15524 in vivo 16415872 - X 2 P16333 O15524 in vitro 10022833 - X 2 P16333 O15524 in vitro 10022833 - X 2 O15524 O60674 in vitro 10064597,11971965,9202126 - X 2 O15524 O60674 in vivo 10064597,11971965,9202126 - X 2 O15524 O60674 two hybrid 10064597,11971965,9202126 - X 2 O15524 P07333 in vivo 10022833,11297560 - X 2 O15524 P07333 in vitro 10022833,11297560 - X 2 O15524 P07333 two hybrid 10022833,11297560 - X 2 O15524 P15498 in vivo 10022833 - X 2 O15524 P15498 two hybrid 10022833 - X 2 O15524 P15498 in vitro 10022833 - X 2 O15524 two hybrid 10022833 - X 2 O15524 P42680 two hybrid 9341160 - X 2 O15524 P42680 in vitro 9341160 - X 2 O15524 P42680 in vivo 9341160 - X 2 O15524 in vivo 12228220 - X 2 O15524 P15498 two hybrid 10022833 - X 2 O15524 P15498 in vitro 10022833 - X 2 O15524 P15498 in vivo 10022833 - X 2 O15524 two hybrid 10022833 - X 2 O15524 P42680 in vivo 9341160 - X 2 O15524 P42680 two hybrid 9341160 - X 2 O15524 P42680 in vitro 9341160 - X 2 O15524 in vivo 12228220 - X 2 O15524 Q8N668 in vitro 17183367 - X 2 O15524 O60674 two hybrid 10064597,11971965,9202126 - X 2 O15524 O60674 in vivo 10064597,11971965,9202126 - X 2 O15524 O60674 in vitro 10064597,11971965,9202126 - X 2 O15524 P07333 in vivo 10022833,11297560 - X 2 O15524 P07333 in vitro 10022833,11297560 - X 2 O15524 P07333 two hybrid 10022833,11297560 - X 2 O15524 Q8N668 in vitro 17183367 - X 2 Q04206-4 O15524 in vitro 14690596,17183367 - X 2 Q04206-4 O15524 in vivo 14690596,17183367 - X 2 Q04206-4 O15524 in vitro 14690596,17183367 - X 2 Q04206-4 O15524 in vivo 14690596,17183367 - X 2 P61073 O15524 in vivo 12163560 - X 2 P61073 O15524 in vivo 12163560 - X 2 Q08881 O15524 in vitro 10022833 - X 2 Q08881 O15524 in vitro 10022833 - X 2 P09619 O15524 two hybrid 10022833 - X 2 P09619 O15524 two hybrid 10022833 - X 2 O15524 two hybrid 11297560 - X 2 O15524 in vitro 11297560 - X 2 O15524 in vivo 11297560 - X 2 O15524 in vitro 11297560 - X 2 O15524 two hybrid 11297560 - X 2 O15524 in vivo 11297560 - X 2 O15524 fluorescence microscopy 19327355 colocalization C 3 P04626 O15524 protein array 16273093 direct interaction X 2 P04626 O15524 protein array 16273093 direct interaction X 2 O15524 Q04206 pull down 17183367 physical association X 2 O15524 Q04206 pull down 17183367 physical association X 2 O15524 Q13748 fluorescence microscopy 19327355 colocalization X 2 Q99683 O15524 pull down 16407264 association X 2 O15524 pull down 19327355 association C 5 O15524 pull down 19327355 association C 6 O15524 pull down 19327355 association C 6 A0A024R7Y5 O15524 two hybrid array 16643902 physical association X 2 A0A024R7Y5 O15524 pull down 17183367 physical association X 2 P05888 O15524 cosedimentation 19327355 colocalization X 2 A0A024R759 O15524 fluorescence polarization spectroscopy 24728074 direct interaction X 2 O15524 O60674 two hybrid 10421843 physical association X 2 O15524 Q8N668 pull down 17183367 physical association X 2 O15524 Q8N668 anti bait coimmunoprecipitation 17183367 physical association X 2 O15524 Q8N668 pull down 17183367 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B SOCS1 IFNAR1 MI:0004(affinity chromatography technology) 21757742 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_164393 prey bait SOCS1 ALK MI:0004(affinity chromatography technology) 14968112 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_122241 prey bait SOCS1 EGFR MI:0004(affinity chromatography technology)|MI:0493(in vivo) 12070153 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_111228|HPRD_33636 prey|- bait|- SOCS1 ABL1 MI:0004(affinity chromatography technology) 22787435 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_260804 bait prey SOCS1 COMMD1 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0492(in vitro)|MI:0006(anti bait coimmunoprecipitation) 17183367 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(intact)|MI:0471(mint)|(biogrid)|(intact)|MI:0471(mint)|MI:0468(hprd)|(intact) MINT_52479|MINT_84967|MINT_84966|BIOGRID_121975|MINT_52471|UniProt_88389|MINT_84975|BIOGRID_121978|UniProt_88396|MINT_52470|HPRD_32349|UniProt_88399 bait|bait|prey|prey|bait|bait|bait|bait|bait|prey|-|prey prey|prey|bait|bait|prey|prey|prey|prey|prey|bait|-|bait SOCS1 NRF1 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_295231 prey bait SOCS1 GRB2 MI:0493(in vivo)|MI:0018(two hybrid) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_4408|BIOGRID_98299 -|prey -|bait SOCS1 JAK1 MI:0004(affinity chromatography technology)|MI:0492(in vitro) 10707961,11133764 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_212460|HPRD_36645 prey|- bait|- SOCS1 UBC MI:0004(affinity chromatography technology) 17898043 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_117876 bait prey SOCS1 TUBG1 MI:0401(biochemical) 15456882 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association) (biogrid) BIOGRID_197752 bait prey SOCS1 PDGFRB MI:0493(in vivo) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_17097 - - SOCS1 CSF1 MI:0493(in vivo) 11297560 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_22869 - - SOCS1 RELA MI:0493(in vivo)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 14690596,17183367,21084693 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|MI:0471(mint)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|(biogrid) HPRD_32351|MINT_84977|BIOGRID_164968|BIOGRID_164969|MINT_52481|MINT_52480|UniProt_88397|UniProt_88398|BIOGRID_121981|BIOGRID_121982|BIOGRID_199946|MINT_84976|BIOGRID_199945|BIOGRID_199947 -|bait|prey|bait|bait|prey|prey|bait|prey|bait|bait|prey|prey|prey -|prey|bait|prey|prey|bait|bait|prey|bait|prey|prey|bait|bait|bait SOCS1 AXL MI:0493(in vivo) 12470648 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_17356 - - SOCS1 PDCD1 MI:0004(affinity chromatography technology) 21263070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_212223 prey bait SOCS1 CRK MI:0018(two hybrid) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_98300 prey bait SOCS1 FGFR3 MI:0004(affinity chromatography technology) 16410555 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_213164 bait prey SOCS1 TCEB1 MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0492(in vitro) 10051596,11384984,16643902,17183367,21119685,22787435 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(intact)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0468(hprd)|(biogrid)|MI:0471(mint)|MI:0468(hprd) BIOGRID_260803|UniProt_88395|MINT_52478|BIOGRID_159235|MINT_84974|UniProt_85144|MINT_49823|UniProt_167602|HPRD_7726|BIOGRID_103644|MINT_82042|HPRD_40453 bait|bait|bait|prey|bait|bait|bait|bait|-|bait|bait|- prey|prey|prey|bait|prey|prey|prey|prey|-|prey|prey|- SOCS1 TCEB2 MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0492(in vitro) 10051596,11384984,21119685 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|- MI:0468(hprd)|(biogrid)|MI:0468(hprd) HPRD_7720|BIOGRID_159233|HPRD_40453 -|prey|- -|bait|- SOCS1 MAP3K5 MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology) 16407264,18776134 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid) MINT_80033|MINT_48064|BIOGRID_197189|BIOGRID_124853|BIOGRID_124850|BIOGRID_197190|UniProt_84630|BIOGRID_124851 unspecified role|unspecified role|prey|bait|bait|bait|unspecified role|prey unspecified role|unspecified role|bait|prey|prey|prey|unspecified role|bait SOCS1 JAK2 MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 10064597,10421843,10455112,11314018,11713228,11971965,14522994,18508766,19287004,9202126,9344848 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid) MINT_79940|BIOGRID_106819|BIOGRID_106818|BIOGRID_103161|BIOGRID_103160|BIOGRID_109441|BIOGRID_184288|BIOGRID_103162|MINT_47981|BIOGRID_115631|BIOGRID_77377|UniProt_66966|BIOGRID_208625|BIOGRID_218828|BIOGRID_208627|BIOGRID_210337|HPRD_36701|BIOGRID_115627|BIOGRID_96485 unspecified role|bait|bait|bait|prey|bait|prey|bait|unspecified role|prey|prey|unspecified role|bait|prey|prey|bait|-|prey|bait unspecified role|prey|prey|prey|bait|prey|bait|prey|unspecified role|bait|bait|unspecified role|prey|bait|bait|prey|-|bait|prey SOCS1 CYTIP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23469018 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_258148|BIOGRID_258150 prey|prey bait|bait SOCS1 CXCR4 MI:0493(in vivo) 12163560 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_24226 - - SOCS1 IRF3 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21079688 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_164018|BIOGRID_164019 prey|bait bait|prey SOCS1 TCEB3 MI:0004(affinity chromatography technology)|MI:0492(in vitro) 10051596,11384984 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_103645|HPRD_40453 bait|- prey|- SOCS1 VAV1 MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 10022833,10747851 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_98295|BIOGRID_199108|HPRD_54 bait|bait|- prey|prey|- SOCS1 IFNGR1 MI:0493(in vivo) 15522878 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_24168 - - SOCS1 DAB1 MI:0004(affinity chromatography technology) 17974915 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_201392 bait prey SOCS1 RASA1 MI:0415(enzymatic study)|MI:0415(enzymatic study) 18556463 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_211546|BIOGRID_211547 prey|bait bait|prey SOCS1 TUBA3C MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy) 19327355 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization) MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact) MINT_40806|UniProt_99759|MINT_70367|MINT_40807|MINT_70366|UniProt_99760 neutral component|neutral component|neutral component|neutral component|neutral component|neutral component neutral component|neutral component|neutral component|neutral component|neutral component|neutral component SOCS1 ATR MI:0004(affinity chromatography technology) 20005840 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_219138 prey bait SOCS1 PTPN11 MI:0004(affinity chromatography technology) 14522994 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_184289 bait prey SOCS1 ATM MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20005840 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_219139|BIOGRID_219137 prey|prey bait|bait SOCS1 p53 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20005840 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_219136|BIOGRID_219135|BIOGRID_219134 bait|prey|prey prey|bait|bait SOCS1 ERBB2 MI:0089(protein array)|MI:0089(protein array)|MI:0089(protein array)|MI:0089(protein array)|MI:0089(protein array)|MI:0686(unspecified method)|MI:0089(protein array) 16273093 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|(biogrid)|(intact) MINT_75807|MINT_45353|MINT_75808|MINT_45354|UniProt_83559|BIOGRID_258369|UniProt_83341 bait|bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey|prey SOCS1 NCK1 MI:0018(two hybrid)|MI:0493(in vivo) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_98302|HPRD_7129 prey|- bait|- SOCS1 TIRAP MI:0493(in vivo)|MI:0004(affinity chromatography technology) 16415872 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_25708|BIOGRID_201275 -|bait -|prey SOCS1 TYK2 MI:0004(affinity chromatography technology) 21757742 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_164396 prey bait SOCS1 IRS1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 12228220,17276034 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_95909|BIOGRID_201390|HPRD_36377 prey|bait|- bait|prey|- SOCS1 ITK MI:0018(two hybrid)|MI:0493(in vivo) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_98304|HPRD_3459 prey|- bait|- SOCS1 IRS2 MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 12228220 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_95908|HPRD_25411|BIOGRID_95910 bait|-|prey prey|-|bait SOCS1 FYN MI:0018(two hybrid)|MI:0493(in vivo) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_98303|HPRD_34381 prey|- bait|- SOCS1 LCK MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21234523 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_214641|BIOGRID_214637 bait|prey prey|bait SOCS1 INSR MI:0492(in vitro)|MI:0004(affinity chromatography technology) 11342531,15169905 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_36502|BIOGRID_214719 -|prey -|bait SOCS1 PIK3R1 MI:0493(in vivo) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_772 - - SOCS1 TEC MI:0096(pull down)|MI:0096(pull down)|MI:0493(in vivo) 9341160 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_105276|BIOGRID_105277|HPRD_7305 prey|prey|- bait|bait|- SOCS1 PIM2 MI:0492(in vitro) 11854514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_5532 - - SOCS1 KIT MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_98293|BIOGRID_98292|HPRD_130 bait|prey|- prey|bait|- SOCS1 GHR MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 10585430 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_8033|BIOGRID_101892|BIOGRID_101891 -|prey|prey -|bait|bait PIK3R2 SOCS1 MI:0493(in vivo) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25879 - - SOCS1 CSF1R MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 11297560 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_39031|BIOGRID_77447|BIOGRID_108321|BIOGRID_108322 -|prey|prey|prey -|bait|bait|bait SOCS1 IL2RB MI:0492(in vitro)|MI:0004(affinity chromatography technology) 11133764 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_36036|BIOGRID_106628 -|prey -|bait SOCS1 ETV6 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 11314018 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_208626|BIOGRID_208624 prey|bait bait|prey SOCS1 FLT3 MI:0018(two hybrid)|MI:0493(in vivo) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_98294|HPRD_34231 bait|- prey|- SOCS1 VAV2 MI:0018(two hybrid)|MI:0493(in vivo) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_98296|HPRD_6967 bait|- prey|- SOCS1 MET MI:0053(fluorescence polarization spectroscopy) 24728074 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (intact) UniProt_133101 neutral component neutral component SOCS2 SOCS1 MI:0004(affinity chromatography technology) 17898043 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_117875 bait prey SOCS1 VHL MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 11384984,21685897 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_40453|BIOGRID_199678|BIOGRID_199679 -|prey|bait -|bait|prey SOCS1 MPL MI:0492(in vitro)|MI:0004(affinity chromatography technology) 10517496 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_24804|BIOGRID_103244 -|prey -|bait SOCS1 JAK3 MI:0492(in vitro) 11133764 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_6466 - - SOCS1 IGF1R MI:0493(in vivo)|MI:0018(two hybrid) 9727029 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_36298|BIOGRID_77371 -|bait -|prey SOCS1 TEK MI:0493(in vivo) 10022833 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_6578 - - SOCS1 CLEC7A MI:0004(affinity chromatography technology) 21899704 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_189850 bait prey SOCS1 TRIM8 MI:0493(in vivo) 12163497 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_12535 - -

PPI - HINT Gene A Gene B PMID Method Quality SOCS1 JAK2 19287004,10455112,10064597,11971965,11314018,11971965,10064597,10064597,9202126,9202126,9344848,11713228,19287004,9202126,14522994,18508766 0004,0004,0004,0018,0004,0004,0018,0096,0096,0018,0096,0004,0096,0004,0004,0004 LC SOCS1 IRF1 19482358,15545275 0007,0007 LC SOCS1 VAV1 10022833,10022833,10022833,10747851 0004,0018,0019,0004 LC SOCS1 IRS1 17276034,12228220 0004,0004 LC SOCS1 RELA 21084693,14690596,14690596,17183367 0004,0007,0004,0096 LC SOCS1 TCEB1 17183367,21119685,22787435,10051596 0096,0004,0004,0004 LC SOCS1 MAP3K5 19287004,16407264,18776134,19287004,16407264 0007,0096,0004,0096,0004 LC SOCS1 JAK2 19287004,10455112,10064597,11971965,11314018,11971965,10064597,10064597,9202126,9202126,9344848,11713228,19287004,9202126,14522994,18508766 0004,0004,0004,0018,0004,0004,0018,0096,0096,0018,0096,0004,0096,0004,0004,0004 LC SOCS1 IRF1 19482358,15545275 0007,0007 LC SOCS1 VAV1 10022833,10022833,10022833,10747851 0004,0018,0019,0004 LC SOCS1 IRS1 17276034,12228220 0004,0004 LC SOCS1 RELA 21084693,14690596,14690596,17183367 0004,0007,0004,0096 LC SOCS1 TCEB1 17183367,21119685,22787435,10051596 0096,0004,0004,0004 LC SOCS1 MAP3K5 19287004,16407264,18776134,19287004,16407264 0007,0096,0004,0096,0004 LC SOCS1 JAK2 10064597,11971965,11971965,10064597,10421843,10064597,9202126,9202126,9202126 0004,0018,0004,0018,0018,0096,0096,0018,0004 LC SOCS1 CYTIP 23469018,23469018 0004,0018 LC SOCS1 ERBB2 16273093 0089 HT SOCS1 INSR 11342531,11342531,15169905,11342531 0004,0045,0018,0019 LC SOCS1 CSF1R 11297560,10022833,11297560,11297560 0096,0018,0004,0018 LC SOCS1 IGF1R 9727029 0018 LC SOCS1 MET 24728074 0053 HT SOCS1 CSF1 11297560 0018 LC SOCS1 PDGFRB 10022833 0018 LC SOCS1 KIT 10022833,10022833,10022833,10022833 0004,0018,0045,0019 LC SOCS1 VAV1 10022833,10022833,10022833 0004,0018,0019 LC SOCS1 TUBG1 15456882 0401 LC SOCS1 PIK3R1 25814554,25814554,25814554 0397,0018,1356 HT SOCS1 AXL 12470648 0018 LC SOCS1 FLT3 10022833,10022833,10022833 0004,0018,0019 LC SOCS1 TEC 9341160,9341160 0018,0096 LC SOCS1 CRK 25814554,25814554,25814554 0397,0018,1356 HT SOCS1 CRKL 25814554,25814554,25814554 0397,0018,1356 HT SOCS1 VAV2 10022833,10022833 0004,0019 LC SOCS1 GRB2 10022833,10022833,10022833 0004,0019,0096 LC SOCS1 TUBA3C|TUBA3D 19327355 0416 LC SOCS1 TCEB1 16643902 0397 LC SOCS1 Q59F04 10022833 0018 LC SOCS1 Q59HG2 10022833 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P23458 O15524 JAK1 SOCS1 0.21 10707961 Q0PF16 O15524 TRIM5 SOCS1 0.21 25310711 P00519 O15524 ABL1 SOCS1 0.21 22787435 O75553 O15524 DAB1 SOCS1 0.21 17974915 P04637 O15524 TP53 SOCS1 0.569 20005840 P04626 O15524 ERBB2 SOCS1 0.332 16273093 P10721 O15524 KIT SOCS1 0.454 10022833 P06239 O15524 LCK SOCS1 0.376 21234523 P08069 O15524 IGF1R SOCS1 0.309 9727029 P23258 O15524 TUBG1 SOCS1 0.21 15456882 P22607 O15524 FGFR3 SOCS1 0.21 16410555 P36888 O15524 FLT3 SOCS1 0.21 10022833 P27986 O15524 PIK3R1 SOCS1 0.376 25814554 Q06124 O15524 PTPN11 SOCS1 0.21 14522994 P46109 O15524 CRKL SOCS1 0.376 25814554 P46108 O15524 CRK SOCS1 0.569 25814554,10022833 P52735 O15524 VAV2 SOCS1 0.21 10022833 P58753 O15524 TIRAP SOCS1 0.21 16415872 Q14241 O15524 TCEB3 SOCS1 0.21 10051596 Q9BXN2 O15524 CLEC7A SOCS1 0.21 21899704 Q9Y4H2 O15524 IRS2 SOCS1 0.376 12228220 P16333 O15524 NCK1 SOCS1 0.309 10022833 Q9Y4K3 O15524 TRAF6 SOCS1 0.21 26633718 P08581 O15524 MET SOCS1 0.648 25728680,24728074 P00533 O15524 EGFR SOCS1 0.21 12070153 P06213 O15524 INSR SOCS1 0.21 11342531 P06241 O15524 FYN SOCS1 0.309 10022833 Q8N668 O15524 COMMD1 SOCS1 0.659 17183367 P04591 O15524 GAG SOCS1 0.872 18172216,19327355 P10912 O15524 GHR SOCS1 0.454 10585430 P05888 O15524 GAG SOCS1 0.236 19327355 Q99961 O15524 SH3GL1 SOCS1 0.236 unassigned1304 Q13315 O15524 ATM SOCS1 0.454 20005840 Q15369 O15524 TCEB1 SOCS1 0.692 22787435,16643902,10051596,21119685,17183367 P15498 O15524 VAV1 SOCS1 0.376 10022833,10747851 Q04206 O15524 RELA SOCS1 0.765 17183367,21084693 O60759 O15524 CYTIP SOCS1 0.454 23469018 P42680 O15524 TEC SOCS1 0.523 9341160 Q99683 O15524 MAP3K5 SOCS1 0.787 16407264,18776134 P07333 O15524 CSF1R SOCS1 0.623 11297560 O60674 O15524 JAK2 SOCS1 0.99 10421843,10064597,19287004,10455112,18508766,9202126,14522994,9344848,11713228,11314018,11971965 P29597 O15524 TYK2 SOCS1 0.21 21757742 P35568 O15524 IRS1 SOCS1 0.376 17276034,12228220 P32927 O15524 CSF2RB SOCS1 0.21 24086733 Q9UM73 O15524 ALK SOCS1 0.21 14968112 P40238 O15524 MPL SOCS1 0.21 10517496 P40337 O15524 VHL SOCS1 0.376 21685897 P41212 O15524 ETV6 SOCS1 0.376 11314018 Q13617 O15524 CUL2 SOCS1 0.21 19327355 Q13748 O15524 TUBA3D SOCS1 0.126 19327355 P62993 O15524 GRB2 SOCS1 0.309 10022833 Q13535 O15524 ATR SOCS1 0.21 20005840 Q14653 O15524 IRF3 SOCS1 0.376 21079688 P14784 O15524 IL2RB SOCS1 0.21 11133764 Q15116 O15524 PDCD1 SOCS1 0.21 21263070 Q15370 O15524 TCEB2 SOCS1 0.21 21119685 P20936 O15524 RASA1 SOCS1 0.376 18556463 P17181 O15524 IFNAR1 SOCS1 0.21 21757742 Q08881 O15524 ITK SOCS1 0.309 10022833 O15524 O14508 SOCS1 SOCS2 0.21 17898043

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 PIK3R2 SOCS1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS2 SOCS1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 JAK2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS1 CYTIP MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 DAB1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 PCNT MI:0362 inference MI:0461 interaction database SOCS1 ABL1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 EGFR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS1 GH1 MI:0362 inference MI:1106 pathways database SOCS1 GH2 MI:0362 inference MI:1106 pathways database SOCS1 IFNA1 MI:0362 inference MI:1106 pathways database SOCS1 IFNA2 MI:0362 inference MI:1106 pathways database SOCS1 IFNA10 MI:0362 inference MI:1106 pathways database SOCS1 IFNA7 MI:0362 inference MI:1106 pathways database SOCS1 IFNA21 MI:0362 inference MI:1106 pathways database SOCS1 IFNA5 MI:0362 inference MI:1106 pathways database SOCS1 IFNA14 MI:0362 inference MI:1106 pathways database SOCS1 IFNA17 MI:0362 inference MI:1106 pathways database SOCS1 IFNB1 MI:0362 inference MI:1106 pathways database SOCS1 IFNG MI:0362 inference MI:1106 pathways database SOCS1 ERBB2 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 TP53 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 IFNA6 MI:0362 inference MI:1106 pathways database SOCS1 IFNA4 MI:0362 inference MI:1106 pathways database SOCS1 IFNA16 MI:0362 inference MI:1106 pathways database SOCS1 INSR MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 LCK MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 FYN MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 CSF1R MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 IGF1R MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 MET MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 PDGFRB MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 UBC MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 KIT MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS1 GHR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS1 PIM1 MI:0362 inference MI:0461 interaction database SOCS1 IL2RB MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 IFNGR1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SOCS1 VAV1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 NCK1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 IFNAR1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS1 RASA1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 KITLG MI:0362 inference MI:1106 pathways database SOCS1 TAF1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 FGFR3 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 TUBG1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 JAK1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS1 PIK3R1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 SHC1 MI:0362 inference MI:0461 interaction database SOCS1 TYK2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS1 AXL MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 IFNA8 MI:0362 inference MI:1106 pathways database SOCS1 CSF2RB MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 IRS1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 FLT3 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 IFNGR2 MI:0362 inference MI:1106 pathways database SOCS1 MPL MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 VHL MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 ETV6 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 TEC MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 CRK MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 CRKL MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 IFNAR2 MI:0362 inference MI:1106 pathways database SOCS1 NT5C2 MI:0362 inference MI:0461 interaction database SOCS1 STAT2 MI:0362 inference MI:1106 pathways database SOCS1 VAV2 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 TIRAP MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 RBX1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SOCS1 GRB2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS1 TEK MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 RELA MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 PTPN11 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 ITK MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 TRIM28 MI:0362 inference MI:0461 interaction database SOCS1 ATM MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 ATR MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 CUL2 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 CUL4B MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 TCEB3 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 PTK2B MI:0362 inference MI:0461 interaction database SOCS1 IRF3 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 PDCD1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 TCEB1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS1 TCEB2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS1 EZH2 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 PCSK4 MI:0362 inference MI:0461 interaction database SOCS1 COMMD1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 CUL5 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SOCS1 MAP3K5 MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 CLEC7A MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 TRIM8 MI:0362 inference MI:0461 interaction database SOCS1 TRIM5 MI:0362 inference MI:0461 interaction database SOCS1 CISH MI:0362 inference MI:1106 pathways database SOCS1 PAG1 MI:0362 inference MI:0461 interaction database SOCS1 BCLAF1 MI:0362 inference MI:0461 interaction database SOCS1 PIM2 MI:0362 inference MI:0461 interaction database SOCS1 RNF7 MI:0362 inference MI:0461 interaction database SOCS1 ALK MI:0045 experimental interaction detection MI:0461 interaction database SOCS1 IRS2 MI:0045 experimental interaction detection MI:0461 interaction database