Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 22 21964761 rs4821112 G A rs4821112 1.00E-08 URIC ACID BIOLOGICAL MARKERS Blood cell counts and other traits HPOID:0011873|HPOID:0011902|HPOID:0004352|HPOID:0004297|HPOID:0004348|HPOID:0100767|HPOID:0001909|HPOID:0002665|HPOID:0010876|HPOID:0003138|HPOID:0000077|HPOID:0003107 DOID:74|DOID:526|DOID:5844 A intron GWASdb_drug 22 21964761 rs4821112 G A rs4821112 1.04E-08 URIC ACID BIOLOGICAL MARKERS Blood cell counts and other traits HPOID:0011873|HPOID:0011902|HPOID:0004352|HPOID:0004297|HPOID:0004348|HPOID:0100767|HPOID:0001909|HPOID:0002665|HPOID:0010876|HPOID:0003138|HPOID:0000077|HPOID:0003107 DOID:74|DOID:526|DOID:5844 A intron GWASdb_drug 22 21910280 rs8139142 T C rs8139142 1.53E-07 Red blood cell traits HPOID:0001877 DOID:74 T intron GWASdb_trait 22 21912272 rs390408 A G rs390408 8.80E-05 Psoriasis HPOID:0003765 DOID:8893 A intron GWASdb_trait 22 21917190 rs131654 G T rs131654 1.00E-16 Systemic lupus erythematosus HPOID:0002725 DOID:9074 T intron GWASdb_trait 22 21917190 rs131654 G T rs131654 1.50E-04 Systemic lupus erythematosus HPOID:0002725 DOID:9074 T intron GWASdb_trait 22 21917190 rs131654 G T rs131654 8.38E-05 Erythrocyte counts HPOID:0001627|HPOID:0001871 DOID:74|DOID:114 T intron GWASdb_trait 22 21917450 rs131656 G A rs131656 2.64E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21917626 rs131658 C G rs131658 4.46E-06 Hepatitis B HPOID:0012115 DOID:2043 NA intron GWASdb_trait 22 21919671 rs140488 A G rs140488 2.07E-06 Hepatitis B HPOID:0012115 DOID:2043 T,C intron GWASdb_trait 22 21919671 rs201008924 A ACCG rs140488 2.07E-06 Hepatitis B HPOID:0012115 DOID:2043 T,C intron GWASdb_trait 22 21920403 rs131664 G A rs131664 2.06E-06 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21920817 rs59391722 G C rs59391722 8.75E-07 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21920903 rs131665 A G rs131665 2.07E-06 Hepatitis B HPOID:0012115 DOID:2043 T,C intron GWASdb_trait 22 21921294 rs140489 G A rs140489 2.67E-06 Hepatitis B HPOID:0012115 DOID:2043 T,C intron GWASdb_trait 22 21921686 rs140490 G T rs140490 2.33E-06 Hepatitis B HPOID:0012115 DOID:2043 C,A intron GWASdb_trait 22 21922364 rs140491 T C rs140491 2.12E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21922456 rs11089620 C G rs11089620 7.80E-07 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21922904 rs2266959 G T rs2266959 1.00E-16 Inflammatory bowel disease HPOID:0004386 DOID:0050589 G intron GWASdb_trait 22 21922904 rs2266959 G T rs2266959 0.000298 Oligoarticular juvenile idiopathic arthritis HPOID:0005681 DOID:676 G intron GWASdb_trait 22 21922904 rs2266959 G T rs2266959 6.20E-09 Juvenile idiopathic arthritis (including oligoarticular and rheumatoid factor-negative polyarticular JIA) HPOID:0005681 DOID:676 G intron GWASdb_trait 22 21922904 rs2266959 G T rs2266959 6.93E-08 Rheumatoid factor-negative polyarticular juvenile idiopathic arthritis HPOID:0005681 DOID:676 G intron GWASdb_trait 22 21922904 rs2266959 G T rs2266959 1.64E-05 Systemic lupus erythematosus and Systemic sclerosis HPOID:0002725 DOID:9074|DOID:1578 G intron GWASdb_trait 22 21922904 rs2266959 G T rs2266959 7.80E-07 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21923144 rs140492 A C rs140492 2.33E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21925017 rs2256609 A G rs2256609 8.75E-07 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21927064 rs140498 G A rs140498 2.07E-06 Hepatitis B HPOID:0012115 DOID:2043 T intron GWASdb_trait 22 21927231 rs140499 C T rs140499 2.07E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21928597 rs2266961 C G rs2266961 8.98E-07 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21928641 rs181359 G A rs181359 5.00E-16 Crohn's disease HPOID:0100280 DOID:8778 C intron GWASdb_trait 22 21928641 rs181359 G A rs181359 2.07E-06 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21928916 rs181360 T G rs181360 3.07E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21930093 rs73166619 C T rs73166619 8.98E-07 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21930777 rs5754166 C T rs5754166 8.02E-07 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21932068 rs181362 C T rs181362 1.00E-08 HDL cholesterol HPOID:0003107 DOID:14502|DOID:1461|DOID:3393 A intron GWASdb_trait 22 21932068 rs181362 C T rs181362 4.00E-18 HDL cholesterol HPOID:0003107 DOID:14502|DOID:1461|DOID:3393 A intron GWASdb_trait 22 21932068 rs181362 C T rs181362 2.07E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21932264 rs181363 A G rs181363 2.07E-06 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21933780 rs181366 C T rs181366 2.07E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21936152 rs66534072 C G rs66534072 2.64E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21936835 rs374387 C A rs374387 5.11E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21938224 rs5749485 A C rs5749485 2.64E-06 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21938590 rs5998576 C T rs5998576 3.08E-06 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21938863 rs73166622 G C rs73166622 2.78E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21939675 rs5754217 G T rs5754217 7.53E-08 Systemic lupus erythematosus HPOID:0002725 DOID:9074 T intron GWASdb_trait 22 21939675 rs5754217 G T rs5754217 6.26E-06 Crohn's disease HPOID:0100280 DOID:8778 T intron GWASdb_trait 22 21939675 rs5754217 G T rs5754217 3.82E-05 Systemic lupus erythematosus HPOID:0002725 DOID:9074 T intron GWASdb_trait 22 21939675 rs5754217 G T rs5754217 1.88E-08 Celiac disease and Rheumatoid arthritis HPOID:0001438|HPOID:0001370 DOID:10608|DOID:7148 T intron GWASdb_trait 22 21939675 rs5754217 G T rs5754217 2.00E-06 Systemic lupus erythematosus HPOID:0002725 DOID:9074 T intron GWASdb_trait 22 21939675 rs5754217 G T rs5754217 9.00E-10 Red blood cell traits HPOID:0001877 DOID:74 T intron GWASdb_trait 22 21939675 rs5754217 G T rs5754217 5.00E-06 Systemic lupus erythematosus HPOID:0002725 DOID:9074 T intron GWASdb_trait 22 21939675 rs5754217 G T rs5754217 9.84E-07 Ulcerative colitis HPOID:0100279 DOID:8577 T intron GWASdb_trait 22 21939675 rs5754217 G T rs5754217 2.38E-06 Hepatitis B HPOID:0012115 DOID:2043 T intron GWASdb_trait 22 21939687 rs5749493 C A rs5749493 2.64E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21940189 rs4820091 T G rs4820091 7.75E-07 Red blood cell traits HPOID:0001877 DOID:74 G intron GWASdb_trait 22 21940189 rs4820091 T G rs4820091 2.46E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21940310 rs5749495 A G rs5749495 1.03E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21941915 rs12484550 C T rs12484550 4.30E-07 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21941981 rs5998599 A G rs5998599 3.02E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21942007 rs9621715 G A rs9621715 4.30E-07 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21942978 rs5754234 A T rs5754234 4.30E-07 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21943938 rs1034329 T C rs1034329 2.50E-06 Hepatitis B HPOID:0012115 DOID:2043 T intron GWASdb_trait 22 21944478 rs2283789 T G rs2283789 2.64E-06 Hepatitis B HPOID:0012115 DOID:2043 T intron GWASdb_trait 22 21945096 rs5749502 T A rs5749502 4.30E-07 Hepatitis B HPOID:0012115 DOID:2043 T intron GWASdb_trait 22 21945851 rs5998619 G A rs5998619 2.51E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21945978 rs73166630 G A,T rs73166630 4.35E-07 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21946173 rs73166632 A G rs73166632 2.64E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21947467 rs2266963 C G rs2266963 3.88E-07 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21949411 rs2070512 A C rs2070512 2.49E-06 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21950405 rs4821104 A G rs4821104 5.70E-07 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21951558 rs417986 C T rs417986 9.06E-06 Hepatitis B HPOID:0012115 DOID:2043 T intron GWASdb_trait 22 21951740 rs5754295 C A rs5754295 2.36E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21953276 rs5994638 A G rs5994638 2.08E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21953288 rs5998644 T C rs5998644 2.08E-06 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21956653 rs2283790 A G rs2283790 4.55E-05 Crohn's disease HPOID:0100280 DOID:8778 G intron GWASdb_trait 22 21956653 rs2283790 A G rs2283790 2.79E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21957992 rs5754323 T C rs5754323 2.19E-06 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21958304 rs2266964 A G rs2266964 2.57E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21958872 rs11089629 T G rs11089629 2.41E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21959038 rs4821108 G C rs4821108 2.53E-06 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21963786 rs5754344 A G rs5754344 7.49E-07 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21964761 rs4821112 G A rs4821112 1.00E-08 Blood cell counts and other traits HPOID:0011873|HPOID:0011902|HPOID:0004352|HPOID:0004297|HPOID:0004348|HPOID:0100767|HPOID:0001909|HPOID:0002665|HPOID:0010876|HPOID:0003138|HPOID:0000077|HPOID:0003107 DOID:74|DOID:526|DOID:5844 A intron GWASdb_trait 22 21964761 rs4821112 G A rs4821112 1.04E-08 Blood cell counts and other traits HPOID:0011873|HPOID:0011902|HPOID:0004352|HPOID:0004297|HPOID:0004348|HPOID:0100767|HPOID:0001909|HPOID:0002665|HPOID:0010876|HPOID:0003138|HPOID:0000077|HPOID:0003107 DOID:74|DOID:526|DOID:5844 A intron GWASdb_trait 22 21964761 rs4821112 G A rs4821112 7.70E-04 Myopia (pathological) HPOID:0000545 DOID:11830 A intron GWASdb_trait 22 21964761 rs4821112 G A rs4821112 2.23E-08 Celiac disease and Rheumatoid arthritis HPOID:0001438|HPOID:0001370 DOID:10608|DOID:7148 A intron GWASdb_trait 22 21964761 rs4821112 G A rs4821112 5.50E-06 Systemic lupus erythematosus HPOID:0002725 DOID:9074 A intron GWASdb_trait 22 21964761 rs4821112 G A rs4821112 9.34E-09 Red blood cell traits HPOID:0001877 DOID:74 A intron GWASdb_trait 22 21964761 rs4821112 G A rs4821112 6.00E-06 Systemic lupus erythematosus HPOID:0002725 DOID:9074 A intron GWASdb_trait 22 21964761 rs4821112 G A rs4821112 1.46E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21964951 rs5754352 C T rs5754352 1.46E-06 Hepatitis B HPOID:0012115 DOID:2043 T intron GWASdb_trait 22 21966442 rs5998672 G A rs5998672 4.48E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21968221 rs738127 G A rs738127 1.47E-06 Hepatitis B HPOID:0012115 DOID:2043 A intron GWASdb_trait 22 21970810 rs4821114 G C rs4821114 7.24E-07 Hepatitis B HPOID:0012115 DOID:2043 G intron GWASdb_trait 22 21971632 rs8139079 T G rs8139079 1.47E-06 Hepatitis B HPOID:0012115 DOID:2043 T intron GWASdb_trait 22 21972401 rs2876971 T G rs2876971 1.28E-06 Hepatitis B HPOID:0012115 DOID:2043 T intron GWASdb_trait 22 21973319 rs4821116 C T rs4821116 2.00E-12 Hepatitis B HPOID:0012115 DOID:2043 C intron GWASdb_trait 22 21976934 rs7444 T C rs7444 2.61E-06 Hepatitis B HPOID:0012115 DOID:2043 C UTR-3 GWASdb_trait 22 21977047 rs7445 C A,G,T rs7445 1.43E-06 Hepatitis B HPOID:0012115 DOID:2043 T UTR-3 GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000185651.14 UBE2L3 603721