PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus NUDCD3 KLHL34 25036637 intact exp P P P GP GP P P P P P GP GP P P P P P GP GP P P P HSP90AB1 KLHL34 22939624 intact exp P P P GP GP P P P P P GP GP P P P P P GP GP P P P HSP90AA1 KLHL34 22939624 biogrid exp P P GP G P G GP P G G P KLHL34 NUDC 25036637 intact exp P P P GP G P P P P P GP GP P P P P P G GP P P P ZBTB22 KLHL34 23023127 pred P P GP GP P P GP GP P P GP GP P P KLHL34 ZBTB32 23023127 pred P P P P P P P P P P BACH1 KLHL34 23023127 pred P P P GP G P P P P GP GP P P P P GP GP P P P VHL KLHL34 23023127 pred G G P P P G G P P P G G P KLHL34 KLHL28 23023127 pred G G P P G G P P G G KLHL34 NACC1 23023127 pred P P P GP GP P P P P GP GP P P P P P G GP P P P SLX4 KLHL34 23023127 pred P P P GP P P P P P GP GP P P P P P P P KLHL18 KLHL34 23023127 pred P P GP GP P P P P GP GP P P GP GP P P KLHL34 BTBD9 23023127 pred P P GP G P P P G GP P P G G P P P KLHL34 BACH2 23023127 pred P P P GP GP P P P P P GP GP P P P P P GP GP P P P KLHL34 ZBTB38 23023127 pred P P GP GP P G GP P G G P P KLHL40 KLHL34 23023127 pred GP G BCL6 KLHL34 23023127 pred P G G P G G P G G P SOCS3 KLHL34 23023127 pred P P P GP GP P P P P GP GP P P P P GP GP P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8N239 P07900-2 affinity chromatography technology 22939624 physical association X 2 Q8N239 A0A024RD80 luminescence based mammalian interactome mapping 22939624 physical association X 2 Q8N239 Q9Y266 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q8N239 Q8IVD9 luminescence based mammalian interactome mapping 25036637 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B HSP90AB1 KLHL34 MI:0729(luminescence based mammalian interactome mapping) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_125041 prey bait HSP90AA1 KLHL34 MI:0004(affinity chromatography technology) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_255409 bait prey KLHL34 PHF8 MI:0007(anti tag coimmunoprecipitation) 23518351 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_128702 bait null

PPI - HINT Gene A Gene B PMID Method Quality HSP90AB1 KLHL34 22939624 0729 HT NUDCD3 KLHL34 25036637 0729 HT KLHL34 NUDC 25036637 0729 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8N239 P08238 KLHL34 HSP90AB1 0.126 22939624 Q8N239 Q8IVD9 KLHL34 NUDCD3 0.126 25036637 Q9Y266 Q8N239 NUDC KLHL34 0.126 25036637 Q8N239 P07900 KLHL34 HSP90AA1 0.126 22939624

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 HSP90AA1 KLHL34 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AB1 KLHL34 MI:0045 experimental interaction detection MI:0461 interaction database NUDCD3 KLHL34 MI:0045 experimental interaction detection MI:0461 interaction database KLHL34 NUDC MI:0045 experimental interaction detection MI:0461 interaction database