PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ZBTB6 ZBTB26 25416956 biogrid,intact exp P P P P P P P P P P P P P P P NCOR1 ZBTB6 9824158 dip exp P P P P P P P P P P P P P P P ZBTB6 ZBTB6 20211142 biogrid exp P P P P P P P P P P P P P P P ZBTB6 SAR1B 26186194 biogrid exp P P P P P P P P P P P P P P SUMO2 ZBTB6 25416956 intact exp P P P P P P P P P P P P P P P ZBTB6 NACC1 19121354 biogrid exp P P P P P P P P P P P P P SKIL ZBTB6 15231748 hprd,biogrid,i2d,mint,intact exp P P P P P P P P P P P P SUMO1 ZBTB6 25416956 biogrid,intact exp P P P P P P P P P P P P P P P ZBTB6 NCOR2 9824158 dip exp P P P P P P P P P P P P P ZBTB6 ATF7IP 15231748 hprd,i2d,mint,intact exp P P P P P P P P P P P P P P BCL6 ZBTB6 9824158, 21836163 dip exp, pred P P P ZBTB6 KBTBD4 23023127 pred P P P P P P P P P P P ZBTB6 BTBD6 23023127 pred P P P P P P ZBTB6 KLHL24 23023127 pred P P P P P ZBTB6 KLHL11 23023127 pred P P P P P P P P P P P P P ZBTB6 KLHL23 23023127 pred P P P ZBTB6 KLHL28 23023127 pred P P P ZBTB6 BTBD7 23023127 pred P P P P P P P P P P P P P P P ZBTB5 ZBTB6 23023127 pred P P P P P P P P P P P P P BTBD17 ZBTB6 23023127 pred P P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q15916 A0A024RAY1 - 15231748 - X 2 Q15916 - 15231748 - X 2 Q15916 Q9HCK0 two hybrid 25416956 direct interaction X 2 Q15916 P55854 affinity chromatography technology 25391492 physical association X 2 A0A024R7E0 Q15916 two hybrid 19121354 direct interaction X 2 A0A024R7E0 Q15916 affinity chromatography technology 19121354 physical association X 2 Q15916 P12757-5 two hybrid 15231748 direct interaction X 2 Q15916 A0A024R3Z2 two hybrid 25416956 direct interaction X 2 Q15916 Q15916 two hybrid 20211142 direct interaction X 2 Q15916 Q9Y618 affinity chromatography technology 9824158 physical association X 2 A0A024RD47 Q15916 affinity chromatography technology 9824158 physical association X 2 P41182 Q15916 affinity chromatography technology 9824158 physical association X 2 Q15916 P12757-3 two hybrid 15231748 - X 2 Q15916 P12757-3 two hybrid 15231748 - X 2 Q15916 A0A024RAY1 two hybrid 15231748 - X 2 Q15916 A0A024RAY1 two hybrid 15231748 - X 2 Q15916 G2XKQ0 two hybrid prey pooling approach 25416956 physical association X 2 Q15916 Q9HCK0 two hybrid prey pooling approach 25416956 physical association X 2 Q15916 G2XKQ0 two hybrid array 25416956 physical association X 2 Q15916 Q9HCK0 two hybrid array 25416956 physical association X 2 Q15916 G2XKQ0 validated two hybrid 25416956 physical association X 2 Q15916 Q9HCK0 validated two hybrid 25416956 physical association X 2 Q15916 A0A024RAY1 two hybrid 15231748 physical association X 2 Q15916 A0A024R3Z2 two hybrid prey pooling approach 25416956 physical association X 2 Q15916 A0A024R3Z2 two hybrid array 25416956 physical association X 2 Q15916 A0A024R3Z2 validated two hybrid 25416956 physical association X 2 P12757 Q15916 two hybrid 15231748 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B ZBTB6 NCOR2 MI:0018(two hybrid) 9824158 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) MI:0465(dip) DIP_52698 - - ZBTB6 uniprotkb:(gene name) MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_38596 - - ZBTB6 NACC1 MI:0018(two hybrid)|MI:0018(two hybrid) 19121354 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_211827|BIOGRID_211830 prey|prey bait|bait NCOR1 ZBTB6 MI:0018(two hybrid) 9824158 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) MI:0465(dip) DIP_52697 - - ZBTB6 ATF7IP MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(intact) MINT_61232|MINT_32384|UniProt_78905 prey|prey|prey bait|bait|bait BCL6 ZBTB6 MI:0018(two hybrid) 9824158 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) MI:0465(dip) DIP_52696 - - SKIL ZBTB6 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association) MI:0471(mint)|(intact)|(biogrid)|MI:0468(hprd)|MI:0471(mint) MINT_31766|UniProt_78656|BIOGRID_258961|HPRD_38394|MINT_60550 bait|bait|bait|-|bait prey|prey|prey|-|prey

PPI - HINT Gene A Gene B PMID Method Quality ZBTB6 SAR1B 26186194 0004 HT ZBTB6 SAR1B 26186194 0004 HT G2XKQ0 ZBTB6 25416956,25416956,25416956 1112,0397,1356 HT SKIL ZBTB6 15231748 0018 HT SUMO1 ZBTB6 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT ZBTB6 ZBTB6 20211142 0018 HT ZBTB6 ATF7IP 15231748 0018 HT ZBTB6 NACC1 19121354,19121354 0018,0004 LC ZBTB6 ZBTB26 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9Y618 Q15916 NCOR2 ZBTB6 0.033 9824158 Q8IZU1 Q15916 FAM9A ZBTB6 0.236 unassigned1304 Q96RE7 Q15916 NACC1 ZBTB6 0.454 19121354 Q9H8W4 Q15916 PLEKHF2 ZBTB6 0.236 unassigned1304 Q15916 P15622 ZBTB6 ZNF250 0.236 unassigned1304 Q15916 P10074 ZBTB6 ZBTB48 0.236 unassigned1304 Q15916 G2XKQ0 ZBTB6 G2XKQ0 0.49 25416956,unassigned1304 Q9HCK0 Q15916 ZBTB26 ZBTB6 0.583 25416956,unassigned1304 Q15916 P41182 ZBTB6 BCL6 0.033 9824158 Q15916 P63165 ZBTB6 SUMO1 0.454 25416956 Q15916 O75376 ZBTB6 NCOR1 0.033 9824158 Q15916 P12757 ZBTB6 SKIL 0.332 15231748 Q15916 Q15916 ZBTB6 ZBTB6 0.21 20211142 Q6VMQ6 Q15916 ATF7IP ZBTB6 0.183 15231748 Q9Y6B6 Q15916 SAR1B ZBTB6 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SKIL ZBTB6 MI:0045 experimental interaction detection MI:0461 interaction database SUMO3 ZBTB6 MI:0045 experimental interaction detection MI:0461 interaction database SUMO1 ZBTB6 MI:0045 experimental interaction detection MI:0461 interaction database ZBTB6 ATF7IP MI:0045 experimental interaction detection MI:0461 interaction database ZBTB6 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database ZBTB6 ZBTB26 MI:0045 experimental interaction detection MI:0461 interaction database ZBTB6 SAR1B MI:0045 experimental interaction detection MI:0461 interaction database