Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 16 75102952 rs9936747 T C rs9936747 3.06E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 T intron GWASdb_drug 16 75123994 rs4447456 G T rs4447456 9.22E-05 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 G intron GWASdb_drug 16 75132865 rs62059203 G C rs62059203 1.31E-04 COCAINE CDK1 PROTEIN, HUMAN|NUCLEAR RECEPTOR CO-REPRESSOR 2|NCOR2 PROTEIN, HUMAN|CYCLIN-DEPENDENT KINASES|DOPAMINE UPTAKE INHIBITORS Cocaine dependence HPOID:0000707 DOID:9975 G intron GWASdb_drug 16 75132865 rs62059203 G C rs62059203 4.92E-04 COCAINE CDK1 PROTEIN, HUMAN|NUCLEAR RECEPTOR CO-REPRESSOR 2|NCOR2 PROTEIN, HUMAN|CYCLIN-DEPENDENT KINASES|DOPAMINE UPTAKE INHIBITORS Cocaine dependence HPOID:0000707 DOID:9975 G intron GWASdb_drug 16 75086875 rs17684886 A T rs17684886 6.80E-06 Diabetic retinopathy HPOID:0000819|HPOID:0000488 DOID:8947 A intron GWASdb_trait 16 75090134 rs6564199 A T rs6564199 8.42E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 A intron GWASdb_trait 16 75091897 rs16953919 G T rs16953919 9.02E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 G intron GWASdb_trait 16 75102952 rs9936747 T C rs9936747 3.06E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 T intron GWASdb_trait 16 75102952 rs9936747 T C rs9936747 1.80E-05 Diabetic retinopathy HPOID:0000819|HPOID:0000488 DOID:8947 T intron GWASdb_trait 16 75106409 rs8049357 C G rs8049357 8.54E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 C intron GWASdb_trait 16 75107716 rs13337868 G C rs13337868 2.00E-05 Diabetic retinopathy HPOID:0000819|HPOID:0000488 DOID:8947 G intron GWASdb_trait 16 75108287 rs11641489 G A rs11641489 9.48E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 G intron GWASdb_trait 16 75123994 rs4447456 G T rs4447456 9.22E-05 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 G intron GWASdb_trait 16 75132865 rs62059203 G C rs62059203 1.31E-04 Cocaine dependence HPOID:0000707 DOID:9975 G intron GWASdb_trait 16 75132865 rs62059203 G C rs62059203 4.92E-04 Cocaine dependence HPOID:0000707 DOID:9975 G intron GWASdb_trait 16 75141060 rs989925 A G rs989925 3.98E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 T intron GWASdb_trait 16 75144408 rs1043509 A T rs1043509 1.35E-04 Prostate cancer mortality HPOID:0012125 DOID:10283 A UTR-3 GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000186187.11 ZNRF1 612060