DNA & RNA Element - microRNA Mirbase Acc miRNA Name Gene ID Gene Symbol miRNA Alignment Alignment Gene Alignment miRNA Start miRNA End Gene Start Gene End Genome Coordinates Conservation Align Score Seed Cat Energy mirSVR Score MIMAT0004489 hsa-miR-16-1* 168433 RNF133 agucgUCGUGUCA--AUUAUGACc | || :|| |||||||| gugaaAUCA-GGUCCUAAUACUGa 2 18 37 59 [hg19:7:122337783-122337805:-] 0.6224 146 7 -11.06 -0.8212 MIMAT0004503 hsa-miR-29a* 168433 RNF133 gacUUGUG-GUUUUCUUUAGUCa ||| : :| : |||||||| uuaAACCUGUAUGUGAAAUCAGg 2 20 25 47 [hg19:7:122337795-122337817:-] 0.6224 150 7 -12.46 -0.3575 MIMAT0004596 hsa-miR-138-2* 168433 RNF133 uugGGACCACAGCACUUUA-UCg ||| || | ||||||| || aaaCCU-GUAU-GUGAAAUCAGg 2 20 27 47 [hg19:7:122337795-122337815:-] 0.6224 123 0 -16.11 -0.4915 MIMAT0004673 hsa-miR-29c* 168433 RNF133 cuugugGUCCUCUUUAG-CCAGu :| | |||||| |||| aaccugUAUGUGAAAUCAGGUCc 2 17 28 50 [hg19:7:122337792-122337814:-] 0.6224 124 0 -15.36 -0.9831 MIMAT0000725 hsa-miR-373* 168433 RNF133 ccuuucgcggggguAAAACUCa ||||||| -----uggcaugacUUUUGAGg 2 9 1 17 [hg19:7:122337825-122337841:-] 0.6285 140 7 -8.71 -1.2344 MIMAT0002812 hsa-miR-492 168433 RNF133 uucuuagaacagggcGUCCAGGa ||||||| accuguaugugaaauCAGGUCCu 2 9 29 51 [hg19:7:122337791-122337813:-] 0.6224 140 7 -19.03 -1.0489 MIMAT0002860 hsa-miR-516b* 168433 RNF133 ugGGAGACUUUCCUUCGu |:|:|| ||||||: gaCUUUUG--AGGAAGUg 2 17 7 22 [hg19:7:122337820-122337835:-] 0.6285 133 0 -14.30 -0.1316 MIMAT0006778 hsa-miR-516a-3p 168433 RNF133 ugGGAGACUUUCCUUCGu |:|:|| ||||||: gaCUUUUG--AGGAAGUg 2 17 7 22 [hg19:7:122337820-122337835:-] 0.6285 133 0 -14.30 -0.1316 MIMAT0003215 hsa-miR-552 168433 RNF133 aacagauuggucagUGGACAa |||||| aggaaguguauuaaACCUGUa 2 8 15 35 [hg19:7:122337807-122337827:-] 0.6285 120 6 -10.06 -0.1180 MIMAT0003284 hsa-miR-616* 168433 RNF133 uucagugacUUCCCAAAACUCa | | ||||||| -----uggcAUGACUUUUGAGg 2 14 1 17 [hg19:7:122337825-122337841:-] 0.6285 141 7 -8.24 -1.2317 MIMAT0003331 hsa-miR-655 168433 RNF133 uuuCUCCAAUUGGUACAUAAUa |||| || :||||||| uuuGAGG--AA--GUGUAUUAa 2 20 11 28 [hg19:7:122337814-122337831:-] 0.6285 145 7 -10.95 -1.0015 MIMAT0004916 hsa-miR-888 168433 RNF133 acugACUGU-CGAAAAACUCau ||:|| | ||||||| ----UGGCAUGACUUUUGAGga 3 18 1 18 [hg19:7:122337824-122337841:-] 0.6285 136 0 -13.11 -0.1468 MIMAT0004687 hsa-miR-371-5p 168433 RNF133 ucacgggggugucAAACUCa |||||| ---uggcaugacuUUUGAGg 2 8 1 17 [hg19:7:122337825-122337841:-] 0.6285 120 6 -8.84 -0.2987

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G050330 RNF133 Homo sapiens 168433

DNA & RNA Element - TargetScan Gene Name UTR Region Start UTR Region End AIR Total Normalized 3P-seq-tags & Pseudocounts Strand hg19_chromosome Genome Start Genome End RNF133 1 76 100 5.01 - chr7 122337765 122337841

DNA & RNA Element - RepTar Gene Name miRNA Begin End Profile RNF133 hsa-miR-492 beg:33 end:52 pic:3' TTCTTAGAACAGGGC-GTCCAGGA 5'& ||| |||||||| &5' --------TGTGAAATCAGGTCCT 3' RNF133 ebv-miR-BART4 beg:27 end:50 pic:3' TCGTGTGGTCGT-CG---TAGTCCAG 5'& ||| |.| |. |||||||| &5' -----ACCTGTATGTGAAATCAGGTC 3' RNF133 hsa-miR-1238 beg:0 end:21 pic:3' CCCCGT-CTGTCTGCTCCTTC 5'& |||| ||| .||||||| &5' --GGCATGACTTTTGAGGAAG 3' RNF133 hsa-miR-1296 beg:34 end:54 pic:3' CCTCTACCTCGGTCCCGGGATT 5'& .|| | || ||.||||| &5' ----GTGAAATCA-GGTCCTAA 3' RNF133 hsa-miR-223 beg:43 end:62 pic:3' ACCCCATAAACTGTTTGACTGT 5'& ||| ||||||| &5' ---GGTCCTAAT---ACTGACA 3' RNF133 hsa-miR-23b beg:27 end:41 pic:3' CCATTAGGGACCGTTACACTA 5'& |||| |||||| &5' -------CCTGT--ATGTGA- 3' RNF133 hsa-miR-2909 beg:43 end:55 pic:3' GGTTCTCTACAACCGGGATTG 5'& ||.|||||. &5' ------------GGTCCTAAT 3' RNF133 hsa-miR-29astar beg:26 end:47 pic:3' GACTTGTGGTTTT---CTTTAGTCA 5'& ||| |||||||| &5' ------ACCTGTATGTGAAATCAG- 3' RNF133 hsa-miR-29b-2star beg:27 end:47 pic:3' GATTCGGTGGTACACTTTGGTC 5'& || .||||||||.||| &5' -----CCTGTATGTGAAATCAG 3' RNF133 hsa-miR-3117 beg:32 end:53 pic:3' GACCGTGATATACT------CAGGATA 5'& |||.||| |||||| &5' -------TATGTGAAATCAGGTCCTA- 3' RNF133 hsa-miR-3158 beg:27 end:52 pic:3' CAGGACGT-CTCTCC--TTCGGGAA 5'& ||||.| | || |.|.||| &5' --CCTGTATGTGAAATCAGGTCCT- 3' RNF133 hsa-miR-514b-5p beg:0 end:19 pic:3' TACTAACGGAGGGAGAACTCTT 5'& || ||.|||||.| &5' ------GCATGACTTTTGAGGA 3' RNF133 hsa-miR-655 beg:11 end:28 pic:3' TTTCTCCAATTGGTACATAATA 5'& |||| .||||||| &5' ---GAGGAA----GTGTATTA- 3'

DNA & RNA Element - miRcode Gene Name Type microRNA Seed Position Seed Type Total Cons% Tr Region RNF133 High_conserved miR-130ac/301ab/301b/301b-3p/454/721/4295/3666 chr7:122338661 7-mer-m8 31 CDS RNF133 High_conserved miR-132/212/212-3p chr7:122339006 7-mer-A1 0 5pUTR RNF133 High_conserved miR-93/93a/105/106a/291a-3p/294/295/302abcde/372/373/428/519a/520be/520acd-3p/1378/1420ac chr7:122338660 7-mer-A1 36 CDS RNF133 High_conserved miR-135ab/135a-5p chr7:122339118 7-mer-m8 13 5pUTR RNF133 High_conserved miR-141/200a chr7:122338903 7-mer-m8 9 CDS RNF133 High_conserved miR-146ac/146b-5p chr7:122338456 8-mer 11 CDS RNF133 High_conserved miR-150/5127 chr7:122338800 8-mer 24 CDS RNF133 High_conserved miR-190/190ab chr7:122338838 8-mer 64 CDS RNF133 High_conserved miR-203 chr7:122338832 7-mer-m8 53 CDS RNF133 High_conserved miR-218/218a chr7:122338422 7-mer-m8 13 CDS RNF133 High_conserved miR-223 chr7:122337781 7-mer-A1 47 3pUTR RNF133 High_conserved miR-23abc/23b-3p chr7:122337801 7-mer-A1 9 3pUTR RNF133 High_conserved miR-23abc/23b-3p chr7:122338076 7-mer-m8 51 CDS RNF133 High_conserved miR-338/338-3p chr7:122339088 8-mer 51 5pUTR RNF133 High_conserved miR-34ac/34bc-5p/449abc/449c-5p chr7:122338930 7-mer-m8 13 CDS RNF133 Medium_conserved miR-542-3p chr7:122338379 7-mer-A1 24 CDS RNF133 Medium_conserved miR-590-3p chr7:122338624 7-mer-A1 40 CDS RNF133 Medium_conserved miR-758 chr7:122338377 7-mer-m8 40 CDS RNF133 Medium_conserved miR-876-5p/3167 chr7:122338220 7-mer-A1 20 CDS RNF133 Medium_conserved miR-876-5p/3167 chr7:122338725 7-mer-A1 13 CDS RNF133 Medium_conserved miR-149 chr7:122338598 7-mer-m8 56 CDS RNF133 Medium_conserved miR-296-3p chr7:122337904 7-mer-A1 9 CDS RNF133 Medium_conserved miR-421 chr7:122338040 7-mer-A1 36 CDS RNF133 Medium_conserved miR-485-5p/1698/1703/1962 chr7:122337876 8-mer 20 CDS RNF133 Medium_conserved miR-494 chr7:122338542 8-mer 20 CDS

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score RNF133 RAID00871834 hsa-miR-371a-5p miRNA MIMAT0004687 RNF133 mRNA 168433 Prediction 0.1828