Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 2 160132121 160132121 + Silent SNP T T C TCGA-PK-A5HB-01A-11D-A29I-10 TCGA-PK-A5HB-11A-11D-A29L-10 g.chr2:160132121T>C c.612A>G c.(610-612)cgA>cgG p.R204R BLCA 2 160139395 160139395 + Missense_Mutation SNP G G C TCGA-GU-A766-01A-11D-A32B-08 TCGA-GU-A766-10A-01D-A329-08 g.chr2:160139395G>C c.186C>G c.(184-186)ttC>ttG p.F62L BLCA 2 160139491 160139491 + Silent SNP C C T TCGA-XF-A9T5-01A-11D-A42E-08 TCGA-XF-A9T5-10A-01D-A42H-08 g.chr2:160139491C>T c.90G>A c.(88-90)ttG>ttA p.L30L CESC 2 160139519 160139519 + Missense_Mutation SNP G G C TCGA-IR-A3LA-01A-11D-A22X-09 TCGA-IR-A3LA-10A-01D-A22X-09 g.chr2:160139519G>C c.62C>G c.(61-63)tCc>tGc p.S21C COAD 2 160104921 160104922 + Frame_Shift_Ins INS - - T TCGA-AA-A01Q-01A-01W-A005-10 TCGA-AA-A01Q-10A-01W-A005-10 g.chr2:160104921_160104922insT c.1234_1235insA c.(1234-1236)atafs p.I412fs COAD 2 160112723 160112723 + Silent SNP A A C TCGA-AA-3815-01A-01W-0995-10 TCGA-AA-3815-10A-01W-0995-10 g.chr2:160112723A>C c.1116T>G c.(1114-1116)gcT>gcG p.A372A COAD 2 160112880 160112880 + Missense_Mutation SNP C C T TCGA-AA-A010-01A-01W-A00E-09 TCGA-AA-A010-10A-01W-A00E-09 g.chr2:160112880C>T c.959G>A c.(958-960)cGc>cAc p.R320H COAD 2 160116331 160116331 + Missense_Mutation SNP A A G TCGA-AA-A01Q-01A-01W-A005-10 TCGA-AA-A01Q-10A-01W-A005-10 g.chr2:160116331A>G c.794T>C c.(793-795)gTa>gCa p.V265A COAD 2 160128221 160128222 + Frame_Shift_Ins INS - - A TCGA-D5-5537-01A-21D-1924-10 TCGA-D5-5537-10A-01D-1924-10 g.chr2:160128221_160128222insA c.761_762insT c.(760-762)ctafs p.L254fs COAD 2 160136445 160136445 + Missense_Mutation SNP A A G TCGA-AA-A010-01A-01W-A00E-09 TCGA-AA-A010-10A-01W-A00E-09 g.chr2:160136445A>G c.410T>C c.(409-411)gTt>gCt p.V137A COAD 2 160139504 160139504 + Missense_Mutation SNP G G A TCGA-AA-3678-01A-01W-0900-09 TCGA-AA-3678-10A-01W-0900-09 g.chr2:160139504G>A c.77C>T c.(76-78)gCt>gTt p.A26V COADREAD 2 160092547 160092547 + Missense_Mutation SNP C C A TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr2:160092547C>A c.1428G>T c.(1426-1428)aaG>aaT p.K476N COADREAD 2 160104921 160104922 + Frame_Shift_Ins INS - - T TCGA-AA-A01Q-01A-01W-A005-10 TCGA-AA-A01Q-10A-01W-A005-10 g.chr2:160104921_160104922insT c.1234_1235insA c.(1234-1236)atafs p.I412fs COADREAD 2 160112723 160112723 + Silent SNP A A C TCGA-AA-3815-01A-01W-0995-10 TCGA-AA-3815-10A-01W-0995-10 g.chr2:160112723A>C c.1116T>G c.(1114-1116)gcT>gcG p.A372A COADREAD 2 160112842 160112842 + Missense_Mutation SNP A A T TCGA-CI-6624-01C-11D-1826-10 TCGA-CI-6624-10A-01D-1826-10 g.chr2:160112842A>T c.997T>A c.(997-999)Tca>Aca p.S333T COADREAD 2 160112880 160112880 + Missense_Mutation SNP C C T TCGA-AA-A010-01A-01W-A00E-09 TCGA-AA-A010-10A-01W-A00E-09 g.chr2:160112880C>T c.959G>A c.(958-960)cGc>cAc p.R320H COADREAD 2 160116331 160116331 + Missense_Mutation SNP A A G TCGA-AA-A01Q-01A-01W-A005-10 TCGA-AA-A01Q-10A-01W-A005-10 g.chr2:160116331A>G c.794T>C c.(793-795)gTa>gCa p.V265A COADREAD 2 160128221 160128222 + Frame_Shift_Ins INS - - A TCGA-D5-5537-01A-21D-1924-10 TCGA-D5-5537-10A-01D-1924-10 g.chr2:160128221_160128222insA c.761_762insT c.(760-762)ctafs p.L254fs COADREAD 2 160136445 160136445 + Missense_Mutation SNP A A G TCGA-AA-A010-01A-01W-A00E-09 TCGA-AA-A010-10A-01W-A00E-09 g.chr2:160136445A>G c.410T>C c.(409-411)gTt>gCt p.V137A COADREAD 2 160139504 160139504 + Missense_Mutation SNP G G A TCGA-AA-3678-01A-01W-0900-09 TCGA-AA-3678-10A-01W-0900-09 g.chr2:160139504G>A c.77C>T c.(76-78)gCt>gTt p.A26V DLBC 2 160104988 160104988 + Missense_Mutation SNP T T C TCGA-G8-6324-01A-11D-2210-10 TCGA-G8-6324-10A-01D-2210-10 g.chr2:160104988T>C c.1168A>G c.(1168-1170)Att>Gtt p.I390V ESCA 2 160114319 160114320 + Frame_Shift_Ins INS - - T TCGA-VR-A8EW-01A-11D-A36J-09 TCGA-VR-A8EW-10A-01D-A36M-09 g.chr2:160114319_160114320insT c.901_902insA c.(901-903)atgfs p.M301fs GBMLGG 2 160092648 160092648 + Missense_Mutation SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr2:160092648G>A c.1327C>T c.(1327-1329)Cgt>Tgt p.R443C GBMLGG 2 160136380 160136380 + Missense_Mutation SNP A A T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr2:160136380A>T c.475T>A c.(475-477)Tca>Aca p.S159T HNSC 2 160092614 160092614 + Missense_Mutation SNP G G A TCGA-CR-6481-01A-11D-1870-08 TCGA-CR-6481-10A-01D-1870-08 g.chr2:160092614G>A c.1361C>T c.(1360-1362)tCa>tTa p.S454L HNSC 2 160104982 160104982 + Missense_Mutation SNP C C T TCGA-CR-5248-01A-01D-2012-08 TCGA-CR-5248-10A-01D-2013-08 g.chr2:160104982C>T c.1174G>A c.(1174-1176)Gag>Aag p.E392K HNSC 2 160128239 160128239 + Silent SNP G G T TCGA-QK-A6VB-01A-12D-A34J-08 TCGA-QK-A6VB-10B-01D-A34M-08 g.chr2:160128239G>T c.744C>A c.(742-744)tcC>tcA p.S248S HNSC 2 160136314 160136314 + Missense_Mutation SNP G G C TCGA-MT-A67F-01A-11D-A30E-08 TCGA-MT-A67F-10A-01D-A30H-08 g.chr2:160136314G>C c.541C>G c.(541-543)Ctt>Gtt p.L181V HNSC 2 160139519 160139519 + Missense_Mutation SNP G G C TCGA-BA-6868-01B-12D-1912-08 TCGA-BA-6868-10A-01D-1912-08 g.chr2:160139519G>C c.62C>G c.(61-63)tCc>tGc p.S21C KIPAN 2 160139417 160139417 + Missense_Mutation SNP T T C TCGA-P4-A5ED-01A-11D-A28G-10 TCGA-P4-A5ED-11A-11D-A28G-10 g.chr2:160139417T>C c.164A>G c.(163-165)tAt>tGt p.Y55C KIRP 2 160139417 160139417 + Missense_Mutation SNP T T C TCGA-P4-A5ED-01A-11D-A28G-10 TCGA-P4-A5ED-11A-11D-A28G-10 g.chr2:160139417T>C c.164A>G c.(163-165)tAt>tGt p.Y55C LGG 2 160092648 160092648 + Missense_Mutation SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr2:160092648G>A c.1327C>T c.(1327-1329)Cgt>Tgt p.R443C LGG 2 160136380 160136380 + Missense_Mutation SNP A A T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr2:160136380A>T c.475T>A c.(475-477)Tca>Aca p.S159T LIHC 2 160092653 160092653 + Frame_Shift_Del DEL T T - TCGA-DD-A3A0-01A-11D-A20W-10 TCGA-DD-A3A0-11A-11D-A20W-10 g.chr2:160092653delT c.1322delA c.(1321-1323)aagfs p.K442fs LUAD 2 160104950 160104950 + Silent SNP T T G TCGA-55-7913-01B-11D-2238-08 TCGA-55-7913-10A-01D-2238-08 g.chr2:160104950T>G c.1206A>C c.(1204-1206)tcA>tcC p.S402S LUAD 2 160139338 160139338 + Missense_Mutation SNP C C A TCGA-MN-A4N1-01A-11D-A24P-08 TCGA-MN-A4N1-10A-01D-A24P-08 g.chr2:160139338C>A c.243G>T c.(241-243)tgG>tgT p.W81C PAAD 2 160112844 160112844 + Nonsense_Mutation SNP C C T TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr2:160112844C>T c.995G>A c.(994-996)tGg>tAg p.W332* PRAD 2 160105008 160105008 + Missense_Mutation SNP C C A TCGA-XK-AAJT-01A-11D-A41K-08 TCGA-XK-AAJT-10A-01D-A41N-08 g.chr2:160105008C>A c.1148G>T c.(1147-1149)cGt>cTt p.R383L READ 2 160092547 160092547 + Missense_Mutation SNP C C A TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr2:160092547C>A c.1428G>T c.(1426-1428)aaG>aaT p.K476N READ 2 160112842 160112842 + Missense_Mutation SNP A A T TCGA-CI-6624-01C-11D-1826-10 TCGA-CI-6624-10A-01D-1826-10 g.chr2:160112842A>T c.997T>A c.(997-999)Tca>Aca p.S333T SARC 2 160112887 160112887 + Splice_Site SNP C C T TCGA-DX-AB35-01A-21D-A417-09 TCGA-DX-AB35-11A-11D-A41A-09 g.chr2:160112887C>T c.e9-1 SKCM 2 160092582 160092582 + Missense_Mutation SNP T T A TCGA-GN-A4U3-06A-11D-A32N-08 TCGA-GN-A4U3-10F-01D-A32N-08 g.chr2:160092582T>A c.1393A>T c.(1393-1395)Atg>Ttg p.M465L SKCM 2 160136445 160136445 + Missense_Mutation SNP A A G TCGA-FS-A1ZZ-06A-11D-A197-08 TCGA-FS-A1ZZ-10A-01D-A199-08 g.chr2:160136445A>G c.410T>C c.(409-411)gTt>gCt p.V137A SKCM 2 160139344 160139344 + Silent SNP G G T TCGA-ER-A3PL-06A-11D-A23B-08 TCGA-ER-A3PL-10A-01D-A23B-08 g.chr2:160139344G>T c.237C>A c.(235-237)gtC>gtA p.V79V

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 2 160136433 160136433 single base substitution G A missense_variant S141F 422C>T BRCA-EU 2 160087993 160087993 single base substitution C A downstream_gene_variant BRCA-EU 2 160088055 160088055 deletion of <=200bp T - downstream_gene_variant BRCA-EU 2 160088095 160088095 single base substitution C T downstream_gene_variant BRCA-EU 2 160088248 160088248 single base substitution C T downstream_gene_variant BRCA-EU 2 160088654 160088654 single base substitution C G downstream_gene_variant BRCA-EU 2 160093009 160093009 single base substitution T A intron_variant BRCA-EU 2 160093910 160093910 deletion of <=200bp T - intron_variant BRCA-EU 2 160094100 160094100 single base substitution C G intron_variant BRCA-EU 2 160095089 160095089 single base substitution T C intron_variant BRCA-EU 2 160095393 160095393 single base substitution G A intron_variant BRCA-EU 2 160095758 160095758 single base substitution C G intron_variant BRCA-EU 2 160096227 160096227 single base substitution A T intron_variant BRCA-EU 2 160096765 160096765 single base substitution A C intron_variant BRCA-EU 2 160099525 160099525 single base substitution T C intron_variant BRCA-EU 2 160099617 160099617 single base substitution A T intron_variant BRCA-EU 2 160101128 160101128 single base substitution G C intron_variant BRCA-EU 2 160101886 160101886 deletion of <=200bp A - intron_variant BRCA-EU 2 160102465 160102465 single base substitution A C intron_variant BRCA-EU 2 160103756 160103756 single base substitution A G intron_variant BRCA-EU 2 160103903 160103903 deletion of <=200bp A - intron_variant BRCA-EU 2 160105148 160105148 single base substitution C G intron_variant BRCA-EU 2 160107631 160107631 single base substitution G A intron_variant BRCA-EU 2 160108340 160108340 single base substitution G A intron_variant BRCA-EU 2 160109636 160109636 single base substitution G A intron_variant BRCA-EU 2 160110190 160110190 single base substitution G A intron_variant BRCA-EU 2 160111275 160111275 deletion of <=200bp T - intron_variant BRCA-EU 2 160111282 160111282 single base substitution T A intron_variant BRCA-EU 2 160112608 160112608 single base substitution C T intron_variant BRCA-EU 2 160113244 160113244 single base substitution C T intron_variant BRCA-EU 2 160114499 160114499 single base substitution G C intron_variant BRCA-EU 2 160114499 160114499 single base substitution G C splice_region_variant BRCA-EU 2 160115787 160115787 single base substitution C T intron_variant BRCA-EU 2 160116172 160116172 single base substitution G A intron_variant BRCA-EU 2 160119508 160119508 single base substitution T C intron_variant BRCA-EU 2 160120489 160120489 single base substitution G A intron_variant BRCA-EU 2 160120844 160120844 single base substitution C A intron_variant BRCA-EU 2 160120958 160120958 single base substitution G A intron_variant BRCA-EU 2 160121607 160121607 single base substitution A T intron_variant BRCA-EU 2 160124046 160124046 single base substitution C T intron_variant BRCA-EU 2 160124348 160124348 single base substitution C T intron_variant BRCA-EU 2 160125947 160125947 single base substitution G C intron_variant BRCA-EU 2 160127950 160127950 single base substitution G A intron_variant BRCA-EU 2 160129231 160129231 single base substitution C A intron_variant BRCA-EU 2 160129322 160129322 single base substitution C G intron_variant BRCA-EU 2 160129971 160129971 single base substitution A T intron_variant BRCA-EU 2 160130653 160130654 deletion of <=200bp AA - intron_variant BRCA-EU 2 160130846 160130846 single base substitution C T intron_variant BRCA-EU 2 160132930 160132930 deletion of <=200bp T - intron_variant BRCA-EU 2 160133619 160133619 single base substitution C G intron_variant BRCA-EU 2 160134681 160134681 single base substitution G C intron_variant BRCA-EU 2 160135045 160135045 deletion of <=200bp A - intron_variant BRCA-EU 2 160136830 160136830 insertion of <=200bp - A intron_variant BRCA-EU 2 160139348 160139348 single base substitution G A missense_variant T78I 233C>T BRCA-EU 2 160139999 160139999 single base substitution C G intron_variant BRCA-EU 2 160140184 160140184 single base substitution A G intron_variant BRCA-EU 2 160141380 160141380 single base substitution G A intron_variant BRCA-EU 2 160142547 160142547 single base substitution G A intron_variant BRCA-EU 2 160142927 160142927 single base substitution G C 5_prime_UTR_variant BRCA-EU 2 160142927 160142927 single base substitution G C intron_variant BRCA-EU 2 160143154 160143154 single base substitution G T 5_prime_UTR_variant BRCA-EU 2 160143154 160143154 single base substitution G T upstream_gene_variant BRCA-EU 2 160143249 160143249 single base substitution G A 5_prime_UTR_premature_start_codon_gain_variant BRCA-EU 2 160143249 160143249 single base substitution G A upstream_gene_variant BRCA-EU 2 160144521 160144521 deletion of <=200bp T - upstream_gene_variant BRCA-EU 2 160144581 160144581 single base substitution G A upstream_gene_variant BRCA-EU 2 160145885 160145885 single base substitution T G upstream_gene_variant BRCA-EU 2 160146165 160146165 deletion of <=200bp A - upstream_gene_variant BRCA-EU 2 160146664 160146664 single base substitution T C upstream_gene_variant BRCA-EU 2 160147272 160147272 single base substitution C T upstream_gene_variant BRCA-FR 2 160095758 160095758 single base substitution C G intron_variant BRCA-FR 2 160112293 160112293 single base substitution A T intron_variant BRCA-FR 2 160114499 160114499 single base substitution G C intron_variant BRCA-FR 2 160114499 160114499 single base substitution G C splice_region_variant BRCA-UK 2 160134126 160134126 single base substitution C T intron_variant BRCA-UK 2 160139521 160139521 single base substitution G A synonymous_variant F20F 60C>T BTCA-JP 2 160092704 160092705 deletion of <=200bp AA - intron_variant BTCA-JP 2 160104974 160104974 single base substitution C T intron_variant BTCA-JP 2 160104974 160104974 single base substitution C T synonymous_variant R302R 906G>A BTCA-JP 2 160104974 160104974 single base substitution C T synonymous_variant R394R 1182G>A BTCA-JP 2 160114290 160114290 single base substitution C G intron_variant BTCA-JP 2 160114290 160114290 single base substitution C G missense_variant D311H 931G>C BTCA-JP 2 160139112 160139112 single base substitution T C intron_variant CESC-US 2 160139519 160139519 single base substitution G C missense_variant S21C 62C>G CLLE-ES 2 160144859 160144859 single base substitution T C upstream_gene_variant COAD-US 2 160112881 160112881 single base substitution G T missense_variant R228S 682C>A COAD-US 2 160112881 160112881 single base substitution G T missense_variant R320S 958C>A COAD-US 2 160128221 160128221 insertion of <=200bp - A frameshift_variant L254L? COAD-US 2 160128221 160128221 insertion of <=200bp - A intron_variant COCA-CN 2 160092529 160092529 single base substitution A G 3_prime_UTR_variant COCA-CN 2 160092891 160092891 single base substitution C T intron_variant EOPC-DE 2 160098943 160098943 single base substitution G A intron_variant ESAD-UK 2 160089268 160089268 single base substitution G A downstream_gene_variant ESAD-UK 2 160094387 160094387 single base substitution G A intron_variant ESAD-UK 2 160097690 160097690 single base substitution G C intron_variant ESAD-UK 2 160098737 160098737 single base substitution T A intron_variant ESAD-UK 2 160098758 160098758 single base substitution C T intron_variant ESAD-UK 2 160100674 160100674 single base substitution G T intron_variant ESAD-UK 2 160102399 160102399 single base substitution A T intron_variant ESAD-UK 2 160103137 160103137 single base substitution G A intron_variant ESAD-UK 2 160110189 160110189 single base substitution C T intron_variant ESAD-UK 2 160115493 160115493 single base substitution G A intron_variant ESAD-UK 2 160116000 160116000 single base substitution C A intron_variant ESAD-UK 2 160123717 160123717 single base substitution T C intron_variant ESAD-UK 2 160129151 160129151 single base substitution A T intron_variant ESAD-UK 2 160131099 160131099 single base substitution A C intron_variant ESAD-UK 2 160131630 160131630 single base substitution G A intron_variant ESAD-UK 2 160133949 160133949 insertion of <=200bp - T intron_variant ESAD-UK 2 160134602 160134602 single base substitution G T intron_variant ESAD-UK 2 160134717 160134717 single base substitution G A intron_variant ESAD-UK 2 160135659 160135659 single base substitution C T intron_variant ESAD-UK 2 160135705 160135705 single base substitution C T intron_variant ESAD-UK 2 160136654 160136654 single base substitution G T intron_variant ESAD-UK 2 160140991 160140991 single base substitution G C intron_variant ESAD-UK 2 160142531 160142531 single base substitution G T intron_variant ESAD-UK 2 160143824 160143824 single base substitution C A upstream_gene_variant ESAD-UK 2 160144232 160144232 single base substitution A G upstream_gene_variant ESAD-UK 2 160145037 160145037 deletion of <=200bp A - upstream_gene_variant ESAD-UK 2 160146250 160146250 single base substitution G C upstream_gene_variant ESCA-CN 2 160136345 160136345 single base substitution C G missense_variant M170I 510G>C GACA-CN 2 160104927 160104936 deletion of <=200bp CATATAAATT - frameshift_variant EFIC315 GACA-CN 2 160104927 160104936 deletion of <=200bp CATATAAATT - frameshift_variant EFIC407 GACA-CN 2 160104927 160104936 deletion of <=200bp CATATAAATT - intron_variant KIRP-US 2 160139417 160139417 single base substitution T C missense_variant Y55C 164A>G LAML-KR 2 160092760 160092760 single base substitution A C intron_variant LAML-KR 2 160114315 160114315 single base substitution G A intron_variant LAML-KR 2 160114315 160114315 single base substitution G A synonymous_variant D302D 906C>T LAML-KR 2 160114437 160114437 single base substitution G A intron_variant LICA-CN 2 160112867 160112867 single base substitution C T synonymous_variant Q232Q 696G>A LICA-CN 2 160112867 160112867 single base substitution C T synonymous_variant Q324Q 972G>A LICA-FR 2 160092703 160092703 single base substitution T G splice_acceptor_variant LICA-FR 2 160092904 160092904 single base substitution A C intron_variant LICA-FR 2 160104909 160104909 single base substitution A C intron_variant LICA-FR 2 160104909 160104909 single base substitution A C missense_variant L324R 971T>G LICA-FR 2 160104909 160104909 single base substitution A C missense_variant L416R 1247T>G LINC-JP 2 160087807 160087807 single base substitution C T downstream_gene_variant LINC-JP 2 160092417 160092417 single base substitution T C 3_prime_UTR_variant LINC-JP 2 160110293 160110293 single base substitution A G intron_variant LINC-JP 2 160116397 160116397 single base substitution A T intron_variant LINC-JP 2 160123826 160123826 single base substitution T A intron_variant LINC-JP 2 160126733 160126733 single base substitution A G intron_variant LINC-JP 2 160134316 160134316 single base substitution A T intron_variant LINC-JP 2 160136216 160136216 single base substitution T C intron_variant LINC-JP 2 160138579 160138579 insertion of <=200bp - A intron_variant LINC-JP 2 160139449 160139449 single base substitution T C synonymous_variant E44E 132A>G LIRI-JP 2 160088699 160088699 single base substitution A T downstream_gene_variant LIRI-JP 2 160089749 160089749 single base substitution A C downstream_gene_variant LIRI-JP 2 160090893 160090893 single base substitution T G downstream_gene_variant LIRI-JP 2 160095693 160095693 single base substitution T C intron_variant LIRI-JP 2 160098849 160098849 single base substitution T C intron_variant LIRI-JP 2 160100383 160100383 single base substitution A G intron_variant LIRI-JP 2 160102014 160102014 single base substitution A T intron_variant LIRI-JP 2 160103593 160103593 single base substitution T C intron_variant LIRI-JP 2 160112113 160112113 single base substitution G T intron_variant LIRI-JP 2 160112588 160112588 single base substitution G C intron_variant LIRI-JP 2 160115566 160115566 single base substitution A G intron_variant LIRI-JP 2 160115573 160115573 single base substitution T C intron_variant LIRI-JP 2 160117060 160117060 single base substitution A C intron_variant LIRI-JP 2 160118008 160118008 single base substitution G C intron_variant LIRI-JP 2 160119555 160119555 single base substitution C A intron_variant LIRI-JP 2 160121616 160121616 single base substitution C A intron_variant LIRI-JP 2 160123049 160123049 single base substitution A G intron_variant LIRI-JP 2 160123177 160123177 single base substitution G T intron_variant LIRI-JP 2 160124866 160124866 deletion of <=200bp T - intron_variant LIRI-JP 2 160126389 160126389 single base substitution T A intron_variant LIRI-JP 2 160127284 160127284 single base substitution G A intron_variant LIRI-JP 2 160129553 160129553 single base substitution T G intron_variant LIRI-JP 2 160132111 160132111 single base substitution A G missense_variant C208R 622T>C LIRI-JP 2 160132483 160132483 single base substitution T C intron_variant LIRI-JP 2 160135452 160135452 single base substitution T C intron_variant LIRI-JP 2 160135730 160135730 single base substitution A G intron_variant LIRI-JP 2 160136861 160136861 single base substitution A G intron_variant LIRI-JP 2 160137263 160137263 single base substitution A C intron_variant LIRI-JP 2 160140850 160140850 single base substitution T C intron_variant LIRI-JP 2 160142272 160142272 deletion of <=200bp T - intron_variant LIRI-JP 2 160142298 160142298 single base substitution T C intron_variant LIRI-JP 2 160144129 160144129 single base substitution A G upstream_gene_variant LIRI-JP 2 160146978 160146978 single base substitution C T upstream_gene_variant LIRI-JP 2 160148185 160148185 single base substitution G T upstream_gene_variant LUSC-KR 2 160088875 160088875 single base substitution G C downstream_gene_variant LUSC-KR 2 160104718 160104718 single base substitution T G intron_variant LUSC-KR 2 160111548 160111548 single base substitution G T intron_variant LUSC-KR 2 160118824 160118824 single base substitution C A intron_variant LUSC-KR 2 160122867 160122867 single base substitution T C intron_variant LUSC-KR 2 160127237 160127237 single base substitution C A intron_variant LUSC-KR 2 160131305 160131305 single base substitution C G intron_variant LUSC-KR 2 160133039 160133039 single base substitution C A intron_variant LUSC-KR 2 160138614 160138614 single base substitution C G intron_variant LUSC-KR 2 160143136 160143136 single base substitution A T 5_prime_UTR_variant LUSC-KR 2 160143136 160143136 single base substitution A T upstream_gene_variant MALY-DE 2 160098266 160098266 single base substitution G A intron_variant MALY-DE 2 160102355 160102355 single base substitution A G intron_variant MALY-DE 2 160103022 160103022 single base substitution A T intron_variant MALY-DE 2 160103035 160103035 single base substitution A C intron_variant MALY-DE 2 160103072 160103072 single base substitution A G intron_variant MALY-DE 2 160110538 160110538 single base substitution C T intron_variant MALY-DE 2 160110670 160110670 single base substitution C T intron_variant MALY-DE 2 160112321 160112321 single base substitution T C intron_variant MALY-DE 2 160117410 160117410 single base substitution T G intron_variant MALY-DE 2 160118209 160118209 single base substitution A C intron_variant MALY-DE 2 160129840 160129840 single base substitution C T intron_variant MALY-DE 2 160132104 160132104 single base substitution T C missense_variant Q210R 629A>G MELA-AU 2 160088287 160088287 single base substitution A T downstream_gene_variant MELA-AU 2 160088731 160088731 single base substitution G C downstream_gene_variant MELA-AU 2 160089304 160089304 single base substitution A T downstream_gene_variant MELA-AU 2 160090758 160090758 single base substitution G A downstream_gene_variant MELA-AU 2 160091970 160091970 single base substitution C A downstream_gene_variant MELA-AU 2 160092123 160092123 single base substitution G A downstream_gene_variant MELA-AU 2 160095307 160095308 multiple base substitution (>=2bp and <=200bp) AC TT intron_variant MELA-AU 2 160096373 160096373 single base substitution G A intron_variant MELA-AU 2 160097209 160097209 single base substitution T C intron_variant MELA-AU 2 160097772 160097772 single base substitution G A intron_variant MELA-AU 2 160099433 160099433 single base substitution A G intron_variant MELA-AU 2 160101469 160101469 single base substitution A T intron_variant MELA-AU 2 160101838 160101838 single base substitution A C intron_variant MELA-AU 2 160102140 160102140 single base substitution C T intron_variant MELA-AU 2 160102955 160102955 single base substitution A G intron_variant MELA-AU 2 160104425 160104425 single base substitution T A intron_variant MELA-AU 2 160104431 160104431 single base substitution T A intron_variant MELA-AU 2 160105345 160105346 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 2 160111268 160111268 single base substitution T C intron_variant MELA-AU 2 160114008 160114008 single base substitution C T intron_variant MELA-AU 2 160114065 160114065 insertion of <=200bp - T intron_variant MELA-AU 2 160114119 160114119 single base substitution G T intron_variant MELA-AU 2 160115196 160115196 single base substitution C T intron_variant MELA-AU 2 160115408 160115408 single base substitution G A intron_variant MELA-AU 2 160115604 160115604 single base substitution G A intron_variant MELA-AU 2 160116674 160116674 single base substitution G A intron_variant MELA-AU 2 160118077 160118077 single base substitution C T intron_variant MELA-AU 2 160120106 160120106 single base substitution G A intron_variant MELA-AU 2 160120555 160120556 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 2 160121371 160121371 single base substitution G C intron_variant MELA-AU 2 160123037 160123037 single base substitution A G intron_variant MELA-AU 2 160123457 160123457 single base substitution T C intron_variant MELA-AU 2 160124365 160124365 single base substitution T C intron_variant MELA-AU 2 160125293 160125293 single base substitution G A intron_variant MELA-AU 2 160125997 160125997 single base substitution G A intron_variant MELA-AU 2 160126968 160126968 single base substitution G T intron_variant MELA-AU 2 160127482 160127482 single base substitution A C intron_variant MELA-AU 2 160127583 160127583 single base substitution T C intron_variant MELA-AU 2 160127865 160127865 single base substitution G A intron_variant MELA-AU 2 160129701 160129701 single base substitution G A intron_variant MELA-AU 2 160129950 160129950 single base substitution T C intron_variant MELA-AU 2 160129968 160129968 single base substitution G T intron_variant MELA-AU 2 160130002 160130003 multiple base substitution (>=2bp and <=200bp) GC AA intron_variant MELA-AU 2 160130059 160130059 single base substitution G A intron_variant MELA-AU 2 160130745 160130745 single base substitution T C intron_variant MELA-AU 2 160130942 160130942 single base substitution C T intron_variant MELA-AU 2 160131219 160131219 single base substitution G T intron_variant MELA-AU 2 160131888 160131888 single base substitution C A intron_variant MELA-AU 2 160132289 160132289 single base substitution A C intron_variant MELA-AU 2 160132412 160132412 single base substitution G A intron_variant MELA-AU 2 160132716 160132716 single base substitution G A intron_variant MELA-AU 2 160133337 160133337 single base substitution G A intron_variant MELA-AU 2 160134460 160134460 single base substitution C A intron_variant MELA-AU 2 160134542 160134542 single base substitution C T intron_variant MELA-AU 2 160134611 160134611 single base substitution G A intron_variant MELA-AU 2 160134797 160134797 single base substitution G A intron_variant MELA-AU 2 160134860 160134860 single base substitution G A intron_variant MELA-AU 2 160135502 160135502 single base substitution G A intron_variant MELA-AU 2 160137303 160137303 single base substitution G A intron_variant MELA-AU 2 160138023 160138023 single base substitution G A intron_variant MELA-AU 2 160138243 160138243 single base substitution G A intron_variant MELA-AU 2 160138708 160138708 single base substitution A T intron_variant MELA-AU 2 160140517 160140517 single base substitution G A intron_variant MELA-AU 2 160140992 160140992 single base substitution G A intron_variant MELA-AU 2 160141384 160141385 multiple base substitution (>=2bp and <=200bp) CC AT intron_variant MELA-AU 2 160142507 160142507 single base substitution C T intron_variant MELA-AU 2 160143254 160143254 single base substitution G A 5_prime_UTR_variant MELA-AU 2 160143254 160143254 single base substitution G A upstream_gene_variant MELA-AU 2 160143315 160143315 single base substitution C T upstream_gene_variant MELA-AU 2 160143339 160143339 single base substitution G A upstream_gene_variant MELA-AU 2 160143346 160143346 single base substitution G A upstream_gene_variant MELA-AU 2 160143353 160143353 single base substitution C T upstream_gene_variant MELA-AU 2 160144459 160144459 single base substitution G A upstream_gene_variant MELA-AU 2 160144610 160144610 single base substitution T G upstream_gene_variant MELA-AU 2 160144751 160144751 single base substitution G A upstream_gene_variant MELA-AU 2 160144756 160144756 single base substitution G A upstream_gene_variant MELA-AU 2 160144811 160144811 single base substitution G A upstream_gene_variant MELA-AU 2 160144851 160144851 single base substitution A G upstream_gene_variant MELA-AU 2 160145256 160145256 single base substitution C T upstream_gene_variant MELA-AU 2 160145298 160145298 single base substitution A G upstream_gene_variant MELA-AU 2 160145935 160145935 single base substitution G A upstream_gene_variant MELA-AU 2 160145981 160145981 single base substitution T G upstream_gene_variant MELA-AU 2 160146189 160146189 single base substitution G A upstream_gene_variant MELA-AU 2 160146360 160146360 single base substitution G A upstream_gene_variant MELA-AU 2 160146511 160146511 single base substitution G A upstream_gene_variant MELA-AU 2 160146860 160146860 single base substitution C T upstream_gene_variant MELA-AU 2 160147426 160147426 single base substitution G A upstream_gene_variant MELA-AU 2 160147992 160147993 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 2 160148111 160148111 single base substitution T C upstream_gene_variant MELA-AU 2 160148197 160148197 single base substitution A G upstream_gene_variant ORCA-IN 2 160090079 160090079 single base substitution G C downstream_gene_variant ORCA-IN 2 160123535 160123535 single base substitution C T intron_variant ORCA-IN 2 160135332 160135332 single base substitution G T intron_variant OV-AU 2 160101380 160101380 single base substitution G A intron_variant OV-AU 2 160101579 160101579 single base substitution T G intron_variant OV-AU 2 160105576 160105576 single base substitution C G intron_variant OV-AU 2 160107921 160107921 single base substitution C G intron_variant OV-AU 2 160113600 160113600 single base substitution C A intron_variant OV-AU 2 160129401 160129401 single base substitution G T intron_variant OV-AU 2 160130952 160130952 single base substitution G T intron_variant OV-AU 2 160136384 160136384 single base substitution G C synonymous_variant G157G 471C>G PACA-AU 2 160088168 160088168 insertion of <=200bp - CTTT downstream_gene_variant PACA-AU 2 160090585 160090585 single base substitution C G downstream_gene_variant PACA-AU 2 160090756 160090756 insertion of <=200bp - GTGAACCCAGGAGGCAGAGCTTGCA downstream_gene_variant PACA-AU 2 160097671 160097671 single base substitution A T intron_variant PACA-AU 2 160099558 160099560 deletion of <=200bp ATC - intron_variant PACA-AU 2 160109454 160109454 single base substitution G A intron_variant PACA-AU 2 160110087 160110091 deletion of <=200bp TACTG - intron_variant PACA-AU 2 160114365 160114365 single base substitution T C intron_variant PACA-AU 2 160114365 160114365 single base substitution T C missense_variant T286A 856A>G PACA-AU 2 160116378 160116378 single base substitution T G intron_variant PACA-AU 2 160120453 160120453 single base substitution A G intron_variant PACA-AU 2 160122352 160122352 single base substitution A G intron_variant PACA-AU 2 160128644 160128644 single base substitution G A intron_variant PACA-AU 2 160136150 160136150 single base substitution A T intron_variant PACA-AU 2 160138525 160138525 single base substitution A G intron_variant PACA-AU 2 160139703 160139703 single base substitution G T intron_variant PACA-AU 2 160142547 160142547 single base substitution G T intron_variant PACA-CA 2 160087327 160087327 single base substitution G T downstream_gene_variant PACA-CA 2 160091808 160091808 insertion of <=200bp - T downstream_gene_variant PACA-CA 2 160092402 160092402 single base substitution A G 3_prime_UTR_variant PACA-CA 2 160103796 160103796 single base substitution A G intron_variant PACA-CA 2 160103858 160103858 single base substitution T C intron_variant PACA-CA 2 160104139 160104139 single base substitution C G intron_variant PACA-CA 2 160118140 160118140 single base substitution G C intron_variant PACA-CA 2 160121606 160121606 single base substitution A T intron_variant PACA-CA 2 160121634 160121634 single base substitution C A intron_variant PACA-CA 2 160129180 160129180 deletion of <=200bp A - intron_variant PACA-CA 2 160129771 160129771 single base substitution C A intron_variant PACA-CA 2 160129945 160129945 single base substitution T G intron_variant PACA-CA 2 160130068 160130068 single base substitution A T intron_variant PACA-CA 2 160132197 160132197 insertion of <=200bp - T intron_variant PACA-CA 2 160132359 160132359 deletion of <=200bp A - intron_variant PACA-CA 2 160133013 160133013 single base substitution A G intron_variant PACA-CA 2 160138627 160138627 single base substitution T C intron_variant PACA-CA 2 160139123 160139123 insertion of <=200bp - T intron_variant PACA-CA 2 160144698 160144698 deletion of <=200bp T - upstream_gene_variant PACA-CA 2 160145889 160145889 deletion of <=200bp T - upstream_gene_variant PAEN-AU 2 160134680 160134680 single base substitution T C intron_variant PAEN-IT 2 160119256 160119256 single base substitution G A intron_variant PAEN-IT 2 160126222 160126222 single base substitution T C intron_variant PBCA-DE 2 160094779 160094803 deletion of <=200bp AATTCTATCAAGGAATTTACTTACA - intron_variant PBCA-DE 2 160116365 160116365 single base substitution A C intron_variant PBCA-DE 2 160120570 160120570 single base substitution T G intron_variant PBCA-DE 2 160123988 160123988 deletion of <=200bp T - intron_variant PRAD-CA 2 160102419 160102419 single base substitution A C intron_variant PRAD-CA 2 160104441 160104441 single base substitution T A intron_variant PRAD-CA 2 160135673 160135673 single base substitution G T intron_variant PRAD-CA 2 160139222 160139222 single base substitution G C missense_variant T120S 359C>G PRAD-CA 2 160147274 160147274 single base substitution A G upstream_gene_variant PRAD-UK 2 160094988 160094988 single base substitution G A intron_variant PRAD-UK 2 160098972 160098972 single base substitution G A intron_variant PRAD-UK 2 160103816 160103816 single base substitution T G intron_variant PRAD-UK 2 160104101 160104101 single base substitution G T intron_variant PRAD-UK 2 160114677 160114677 single base substitution G T intron_variant PRAD-UK 2 160135060 160135060 single base substitution T G intron_variant READ-US 2 160112842 160112842 single base substitution A T missense_variant S241T 721T>A READ-US 2 160112842 160112842 single base substitution A T missense_variant S333T 997T>A RECA-EU 2 160087371 160087371 single base substitution G A downstream_gene_variant RECA-EU 2 160091347 160091347 single base substitution A T downstream_gene_variant RECA-EU 2 160099887 160099887 single base substitution T C intron_variant RECA-EU 2 160102942 160102942 single base substitution C A intron_variant RECA-EU 2 160125470 160125470 single base substitution A C intron_variant RECA-EU 2 160126353 160126353 single base substitution A C intron_variant RECA-EU 2 160144369 160144369 single base substitution A G upstream_gene_variant SKCA-BR 2 160088240 160088240 single base substitution T C downstream_gene_variant SKCA-BR 2 160095412 160095412 single base substitution A C intron_variant SKCA-BR 2 160096892 160096892 single base substitution G A intron_variant SKCA-BR 2 160101993 160101993 single base substitution G A intron_variant SKCA-BR 2 160102876 160102876 single base substitution G A intron_variant SKCA-BR 2 160104407 160104421 deletion of <=200bp TATATATATATATAA - intron_variant SKCA-BR 2 160104407 160104439 deletion of <=200bp TATATATATATATAAATATATATATATATATAA - intron_variant SKCA-BR 2 160108838 160108838 single base substitution T C intron_variant SKCA-BR 2 160118391 160118411 deletion of <=200bp ATATATATATATATATATTTT - intron_variant SKCA-BR 2 160118405 160118422 deletion of <=200bp ATATTTTTTTTTTTTTTT - intron_variant SKCA-BR 2 160121464 160121464 single base substitution G A intron_variant SKCA-BR 2 160121468 160121468 single base substitution A G intron_variant SKCA-BR 2 160122890 160122890 single base substitution G A intron_variant SKCA-BR 2 160138181 160138193 deletion of <=200bp TTAAAGCTTTACA - intron_variant SKCA-BR 2 160138197 160138198 deletion of <=200bp TA - intron_variant SKCA-BR 2 160139166 160139166 single base substitution G A intron_variant SKCA-BR 2 160141066 160141066 single base substitution T C intron_variant SKCA-BR 2 160141299 160141299 single base substitution T C intron_variant SKCA-BR 2 160141906 160141906 single base substitution C T intron_variant SKCA-BR 2 160145385 160145385 single base substitution C T upstream_gene_variant SKCA-BR 2 160146305 160146305 insertion of <=200bp - CTT upstream_gene_variant SKCA-BR 2 160148028 160148028 single base substitution C T upstream_gene_variant SKCA-BR 2 160148049 160148049 single base substitution G A upstream_gene_variant SKCM-US 2 160136445 160136445 single base substitution A G missense_variant V137A 410T>C SKCM-US 2 160139344 160139344 single base substitution G T synonymous_variant V79V 237C>A STAD-US 2 160104952 160104952 single base substitution A G intron_variant STAD-US 2 160104952 160104952 single base substitution A G missense_variant S310P 928T>C STAD-US 2 160104952 160104952 single base substitution A G missense_variant S402P 1204T>C STAD-US 2 160128292 160128292 single base substitution A G intron_variant STAD-US 2 160128292 160128292 single base substitution A G missense_variant Y231H 691T>C STAD-US 2 160132102 160132102 single base substitution C A missense_variant D211Y 631G>T STAD-US 2 160139475 160139475 single base substitution G T missense_variant L36M 106C>A THCA-SA 2 160088793 160088793 single base substitution A G downstream_gene_variant UCEC-US 2 160104948 160104948 single base substitution C T intron_variant UCEC-US 2 160104948 160104948 single base substitution C T missense_variant G311E 932G>A UCEC-US 2 160104948 160104948 single base substitution C T missense_variant G403E 1208G>A UCEC-US 2 160104954 160104954 single base substitution G T intron_variant UCEC-US 2 160104954 160104954 single base substitution G T missense_variant S309Y 926C>A UCEC-US 2 160104954 160104954 single base substitution G T missense_variant S401Y 1202C>A UCEC-US 2 160105008 160105008 single base substitution C T intron_variant UCEC-US 2 160105008 160105008 single base substitution C T missense_variant R291H 872G>A UCEC-US 2 160105008 160105008 single base substitution C T missense_variant R383H 1148G>A UCEC-US 2 160112711 160112711 single base substitution T G missense_variant K284N 852A>C UCEC-US 2 160112711 160112711 single base substitution T G missense_variant K376N 1128A>C UCEC-US 2 160112755 160112755 single base substitution C A stop_gained E270* 808G>T UCEC-US 2 160112755 160112755 single base substitution C A stop_gained E362* 1084G>T UCEC-US 2 160136297 160136297 single base substitution G A synonymous_variant C186C 558C>T UCEC-US 2 160136331 160136331 single base substitution C T missense_variant S175N 524G>A UCEC-US 2 160139481 160139481 single base substitution T G missense_variant I34L 100A>C UCEC-US 2 160139542 160139542 single base substitution G A synonymous_variant D13D 39C>T

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand BN24T COSM1613550 c.132A>G p.E44E Substitution - coding silent 2:159282938-159282938 - TCGA-FS-A1ZZ-06 COSM286525 c.410T>C p.V137A Substitution - Missense 2:159279934-159279934 - SNUH_G73_S1 COSM148964 c.906C>T p.D302D Substitution - coding silent 2:159257804-159257804 - Gp5D COSM3300196 c.471C>A p.G157G Substitution - coding silent 2:159279873-159279873 - SJRHB059R COSM3737612 c.583+10T>G p.? Unknown 2:159279751-159279751 - TCGA-AA-A010-01 COSM286525 c.410T>C p.V137A Substitution - Missense 2:159279934-159279934 - 7313 COSM5614953 c.1105G>C p.E369Q Substitution - Missense 2:159256223-159256223 - TCGA-B5-A0JY-01 COSM1008132 c.1128A>C p.K376N Substitution - Missense 2:159256200-159256200 - RK064_C01 COSM1631370 c.622T>C p.C208R Substitution - Missense 2:159275600-159275600 - ESO-582 COSM1270448 c.651G>T p.W217C Substitution - Missense 2:159275571-159275571 - TCGA-IR-A3LA-01 COSM4845134 c.62C>G p.S21C Substitution - Missense 2:159283008-159283008 - LUAD-TLLGS COSM347619 c.835C>T p.Q279* Substitution - Nonsense 2:159257955-159257955 - TCGA-ER-A3PL-06 COSM3568249 c.237C>A p.V79V Substitution - coding silent 2:159282833-159282833 - Au5 COSM5606191 c.780T>G p.D260E Substitution - Missense 2:159259834-159259834 - GC1_T COSM150878 c.1220_1229del10 p.E407fs*3 Deletion - Frameshift 2:159248416-159248425 - 8069168 COSM4406611 c.856A>G p.T286A Substitution - Missense 2:159257854-159257854 - HCC140T COSM5823173 c.972G>A p.Q324Q Substitution - coding silent 2:159256356-159256356 - Ad4 COSM4441023 c.1267G>A p.A423T Substitution - Missense 2:159248378-159248378 - TCGA-BS-A0UV-01 COSM1008130 c.1202C>A p.S401Y Substitution - Missense 2:159248443-159248443 - 7313 COSM5617094 c.845+5G>T p.? Unknown 2:159257940-159257940 - PD4120a COSM165599 c.60C>T p.F20F Substitution - coding silent 2:159283010-159283010 - TCGA-B5-A0JY-01 COSM1008129 c.1208G>A p.G403E Substitution - Missense 2:159248437-159248437 - TCGA-AM-5820-01 COSM148963 c.958C>A p.R320S Substitution - Missense 2:159256370-159256370 - 10-P8045 COSM4582727 c.1421_1422delAC p.H474fs*>3 Deletion - Frameshift 2:159236042-159236043 - 587284 COSM1232714 c.480T>G p.C160W Substitution - Missense 2:159279864-159279864 - CHC703T COSM4957542 c.1274-2A>C p.? Unknown 2:159236192-159236192 - SNUH_G26_S1 COSM4001257 c.983T>C p.F328S Substitution - Missense 2:159256345-159256345 - TCGA-CI-6624-01 COSM1564741 c.997T>A p.S333T Substitution - Missense 2:159256331-159256331 - UM-SCC-2 COSM4001257 c.983T>C p.F328S Substitution - Missense 2:159256345-159256345 - P118 COSM1735786 c.1274-3_1274-2insT p.? Unknown 2:159236192-159236193 - Pat_24_A COSM5860348 c.845G>A p.R282K Substitution - Missense 2:159257945-159257945 - T1154 COSM4741144 c.519G>A p.P173P Substitution - coding silent 2:159279825-159279825 - CHC2362T COSM4957052 c.1247T>G p.L416R Substitution - Missense 2:159248398-159248398 - GC8_T COSM148963 c.958C>A p.R320S Substitution - Missense 2:159256370-159256370 - Gp5D COSM3300189 c.1050T>A p.V350V Substitution - coding silent 2:159256278-159256278 - TCGA-AA-A01Q-01 COSM300133 c.1234_1235insA p.I412fs*3 Insertion - Frameshift 2:159248410-159248411 - TCGA-BR-8372-01 COSM4085875 c.106C>A p.L36M Substitution - Missense 2:159282964-159282964 - GC8_T COSM148964 c.906C>T p.D302D Substitution - coding silent 2:159257804-159257804 - BD236T COSM5518329 c.1274-4_1274-3delTT p.? Unknown 2:159236193-159236194 - CHC703T COSM4957542 c.1274-2A>C p.? Unknown 2:159236192-159236192 - B9-Tumor COSM3933353 c.422C>T p.S141F Substitution - Missense 2:159279922-159279922 - YULAN COSM1686399 c.583+2T>C p.? Unknown 2:159279759-159279759 - TCGA-BS-A0TC-01 COSM1008131 c.1148G>A p.R383H Substitution - Missense 2:159248497-159248497 - T3064 COSM4741143 c.1304A>G p.E435G Substitution - Missense 2:159236160-159236160 - 721LT COSM148963 c.958C>A p.R320S Substitution - Missense 2:159256370-159256370 - PT15_1 COSM3728848 c.1274-3delT p.? Unknown 2:159236193-159236193 - AOCS-139-19-0 COSM4136100 c.471C>G p.G157G Substitution - coding silent 2:159279873-159279873 - TCGA-BR-8381-01 COSM4085873 c.691T>C p.Y231H Substitution - Missense 2:159271781-159271781 - TCGA-AA-3678-01 COSM292935 c.77C>T p.A26V Substitution - Missense 2:159282993-159282993 - TCGA-AX-A0J0-01 COSM1008134 c.558C>T p.C186C Substitution - coding silent 2:159279786-159279786 - TCGA-AX-A0J0-01 COSM1008133 c.1084G>T p.E362* Substitution - Nonsense 2:159256244-159256244 - BD121T COSM5514883 c.1182G>A p.R394R Substitution - coding silent 2:159248463-159248463 - CN-AML-CR-1-Dx COSM148964 c.906C>T p.D302D Substitution - coding silent 2:159257804-159257804 - TCGA-BR-6455-01 COSM4085874 c.631G>T p.D211Y Substitution - Missense 2:159275591-159275591 - TCGA-P4-A5ED-01 COSM3990674 c.164A>G p.Y55C Substitution - Missense 2:159282906-159282906 - 516 COSM5612026 c.748G>T p.D250Y Substitution - Missense 2:159271724-159271724 - TCGA-BR-8078-01 COSM4085872 c.1204T>C p.S402P Substitution - Missense 2:159248441-159248441 - ccRCC-15 COSM1665018 c.456C>A p.S152R Substitution - Missense 2:159279888-159279888 - DLBCL-PatientI COSM221431 c.428C>T p.A143V Substitution - Missense 2:159279916-159279916 - TCGA-AP-A059-01 COSM1008135 c.524G>A p.S175N Substitution - Missense 2:159279820-159279820 - PTC-7C COSM148963 c.958C>A p.R320S Substitution - Missense 2:159256370-159256370 - CHC2362T COSM4957052 c.1247T>G p.L416R Substitution - Missense 2:159248398-159248398 - TCGA-D5-5537-01 COSM1400331 c.761_762insT p.V255fs*7 Insertion - Frameshift 2:159271710-159271711 - LC_C32 COSM1186039 c.79A>G p.T27A Substitution - Missense 2:159282991-159282991 - 2159 COSM5010892 c.1028C>T p.A343V Substitution - Missense 2:159256300-159256300 - BD152T COSM5506806 c.931G>C p.D311H Substitution - Missense 2:159257779-159257779 - PR-03-022 COSM248338 c.987C>T p.T329T Substitution - coding silent 2:159256341-159256341 - LIM2405 COSM4642522 c.529A>G p.K177E Substitution - Missense 2:159279815-159279815 - CSCC-41-T COSM4508727 c.785C>T p.S262F Substitution - Missense 2:159259829-159259829 - TCGA-CW-5581-01 COSM476075 c.1401C>A p.I467I Substitution - coding silent 2:159236063-159236063 - 7313 COSM5614954 c.850G>C p.V284L Substitution - Missense 2:159257860-159257860 - HCC2998 COSM1008133 c.1084G>T p.E362* Substitution - Nonsense 2:159256244-159256244 - TCGA-AA-A010-01 COSM286524 c.959G>A p.R320H Substitution - Missense 2:159256369-159256369 - PD9193a COSM5797294 c.233C>T p.T78I Substitution - Missense 2:159282837-159282837 - SNUH_G73_S1 COSM4415157 c.644A>C p.K215T Substitution - Missense 2:159275578-159275578 - BN24 COSM1613550 c.132A>G p.E44E Substitution - coding silent 2:159282938-159282938 - Pat_41_B COSM5860349 c.145C>T p.P49S Substitution - Missense 2:159282925-159282925 - TCGA-AP-A056-01 COSM1008136 c.100A>C p.I34L Substitution - Missense 2:159282970-159282970 - YUKLAB COSM1691192 c.1141G>A p.G381R Substitution - Missense 2:159248504-159248504 - TCGA-AP-A0LM-01 COSM1008137 c.39C>T p.D13D Substitution - coding silent 2:159283031-159283031 - 169 COSM3728848 c.1274-3delT p.? Unknown 2:159236193-159236193 - 1N60-VS-1T60 COSM4977700 c.633T>C p.D211D Substitution - coding silent 2:159275589-159275589 - ESCC_BICR_040T COSM5430047 c.510G>C p.M170I Substitution - Missense 2:159279834-159279834 - ESO-866 COSM1270449 c.846-1G>T p.? Unknown 2:159257865-159257865 - JEKO-1 COSM1738812 c.275T>G p.M92R Substitution - Missense 2:159282795-159282795 - ESCC_5 COSM5623205 c.1147C>T p.R383C Substitution - Missense 2:159248498-159248498 - SNUH_G73_S1 COSM148963 c.958C>A p.R320S Substitution - Missense 2:159256370-159256370 - pfg097T COSM4763216 c.722C>T p.P241L Substitution - Missense 2:159271750-159271750 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.20798;Hs.20848 2q24.2

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A G IntronicSNV . c.1-126T>C 2 160139706 NSCLC A G Missense p.V137A c.410T>C 2 160136445 CM C A IntronicSNV . c.845+5G>T 2 160114451 NSCLC C A Missense p.D211Y c.631G>T 2 160132102 STAD C A Missense p.W217C c.651G>T 2 160132082 ESCA C A SpliceAcceptorSNV . c.846-1G>T 2 160114376 ESCA C G Missense p.E369Q c.1105G>C 2 160112734 NSCLC C G Missense p.R388T c.1163G>C 2 160104993 LUAD C G Missense p.V284L c.850G>C 2 160114371 NSCLC C T Missense p.E392K c.1174G>A 2 160104982 HNSC C T Missense p.R383H c.1148G>A 2 160105008 UCEC G A Missense p.A26V c.77C>T 2 160139504 COREAD G A Missense p.S454L c.1361C>T 2 160092614 HNSC G A Synonymous p.F20F c.60C>T 2 160139521 BRCA G A Synonymous p.F20F c.60C>T 2 160139521 LUAD G C Missense p.S21C c.62C>G 2 160139519 HNSC T C Missense p.T74A c.220A>G 2 160139361 BRCA