PTM - CPLM Gene Name UniProt ID Type Position Code ANAPC7; APC7 Q9UJX3 Acetylation 263 K ANAPC7; APC7 Q9UJX3 Ubiquitination 99 K ANAPC7; APC7 Q9UJX3 Ubiquitination 293 K ANAPC7; APC7 Q9UJX3 Ubiquitination 379 K ANAPC7; APC7 Q9UJX3 Ubiquitination 467 K ANAPC7; APC7 Q9UJX3 Ubiquitination 477 K ANAPC7; APC7 Q9UJX3 Ubiquitination 491 K ANAPC7; APC7 Q9UJX3 Ubiquitination 364 K ANAPC7; APC7 Q9UJX3 Ubiquitination 193 K ANAPC7; APC7 Q9UJX3 Ubiquitination 263 K ANAPC7; APC7 Q9UJX3 Ubiquitination 264 K ANAPC7; APC7 Q9UJX3 Ubiquitination 462 K ANAPC7; APC7 Q9UJX3 Ubiquitination 482 K ANAPC7; APC7 Q9UJX3 Ubiquitination 181 K ANAPC7; APC7 Q9UJX3 Ubiquitination 353 K ANAPC7; APC7 Q9UJX3 Ubiquitination 551 K ANAPC7; APC7 Q9UJX3 Ubiquitination 460 K ANAPC7; APC7 Q9UJX3 Ubiquitination 115 K ANAPC7; APC7 Q9UJX3 Ubiquitination 139 K ANAPC7; APC7 Q9UJX3 Ubiquitination 153 K ANAPC7; APC7 Q9UJX3 Ubiquitination 288 K ANAPC7; APC7 Q9UJX3 Ubiquitination 107 K ANAPC7; APC7 Q9UJX3 Ubiquitination 306 K

PTM - dbPAF Gene Name UniProt ID Position Type Species ANAPC7; APC7 Q9UJX3 119 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 120 T Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 123 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 125 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 126 T Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 129 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 311 Y Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 313 Y Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 360 Y Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 420 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 422 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 434 Y Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 475 Y Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 51 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 557 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 57 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 58 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 62 T Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 64 S Homo sapiens(Human) ANAPC7; APC7 Q9UJX3 77 Y Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9UJX3 K263-ac Acetylation STICSLEkKSLLRDN Q9UJX3 K467-ac Acetylation KAKTLLDkALTQRPD Q9UJX3 S51-p Phosphorylation MAAAGLHsNVRLLss Q9UJX3 S57-p Phosphorylation HsNVRLLssLLLtMs Q9UJX3 S58-p Phosphorylation sNVRLLssLLLtMsN Q9UJX3 T62-p Phosphorylation LLssLLLtMsNNNPE Q9UJX3 S64-p Phosphorylation ssLLLtMsNNNPELF Q9UJX3 Y77-p Phosphorylation LFSPPQKyQLLVYHA Q9UJX3 S119-p Phosphorylation KTSkVRPstGNsAst Q9UJX3 T120-p Phosphorylation TSkVRPstGNsAstP Q9UJX3 S123-p Phosphorylation VRPstGNsAstPQsQ Q9UJX3 S125-p Phosphorylation PstGNsAstPQsQCL Q9UJX3 T126-p Phosphorylation stGNsAstPQsQCLP Q9UJX3 S129-p Phosphorylation NsAstPQsQCLPSEI Q9UJX3 Y311-p Phosphorylation LIKGMDVyGyLLARE Q9UJX3 Y313-p Phosphorylation KGMDVyGyLLAREGR Q9UJX3 Y360-p Phosphorylation KRYSRALyLGAkAIQ Q9UJX3 S420-p Phosphorylation LIECYLAsNsIREAM Q9UJX3 S422-p Phosphorylation ECYLAsNsIREAMVM Q9UJX3 Y434-p Phosphorylation MVMANNVyKTLGANA Q9UJX3 Y475-p Phosphorylation ALTQRPDyIkAVVKk Q9UJX3 K99-ub Ubiquitination EYRNAVSkYTMALQQ Q9UJX3 K115-ub Ubiquitination KALSKTSkVRPstGN Q9UJX3 K153-ub Ubiquitination YTMLKQDkDAIAILD Q9UJX3 K193-ub Ubiquitination RPSVTSYkEVLRQCP Q9UJX3 K288-ub Ubiquitination YFRAGDNkNSVLkFE Q9UJX3 K293-ub Ubiquitination DNkNSVLkFEQAQML Q9UJX3 K364-ub Ubiquitination RALyLGAkAIQLNSN Q9UJX3 K379-ub Ubiquitination SVQALLLkGAALRNM Q9UJX3 K467-ub Ubiquitination KAKTLLDkALTQRPD Q9UJX3 K477-ub Ubiquitination TQRPDyIkAVVKkAE Q9UJX3 K482-ub Ubiquitination yIkAVVKkAELLSRE Q9UJX3 K491-ub Ubiquitination ELLSREQkYEDGIAL

PTM - dbPTM UniProt ID Position Code Type Resources References Q9UJX3 125 S Phosphorylation PhosphoELM.10011 22067460 Q9UJX3 51 S Phosphorylation PhosphoELM.10011 14657031 Q9UJX3 57 S Phosphorylation PhosphoELM.10011 14657031 Q9UJX3 64 S Phosphorylation PhosphoELM.10011 14657031 Q9UJX3 126 T Phosphorylation PhosphoELM.10011 22067460 Q9UJX3 263 K Acetylation HPRD 9.0 19608861 Q9UJX3 119 S Phosphorylation HPRD 9.0 18669648 Q9UJX3 125 S Phosphorylation HPRD 9.0 18669648 Q9UJX3 126 T Phosphorylation HPRD 9.0 18669648

PTM - HPRD Symbol Position Code Type References ANAPC7 119 S Phosphorylation 18669648 ANAPC7 125 S Phosphorylation 18669648 ANAPC7 126 T Phosphorylation 18669648 ANAPC7 263 K Acetylation 19608861

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9UJX3 17 S 14657031 PLK1 HTP Phosphorylation Q9UJX3 91 S 22067460 HTP Phosphorylation Q9UJX3 23 S 14657031 PLK1 HTP Phosphorylation Q9UJX3 30 S 14657031 PLK1 HTP Phosphorylation Q9UJX3 92 T 22067460 HTP Phosphorylation

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type ANAPC7 IPI00008248 K 229 TICSLEaKKSLLRD acetylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 51434 119538 - K Ubiquitination 21987572 51434 119538 - K Sumoylation 21693764 51434 119538 - K Ubiquitination 21139048 51434 119538 - K Ubiquitination 21890473 51434 119538 - K Ubiquitination 21906983 51434 119538 - K Sumoylation 19471022 51434 119538 - K Ubiquitination 22053931 51434 119538 - K Ubiquitination 22505724 51434 119538 - K FAT10ylation 22797925 51434 119538 - K Ubiquitination 21963094 51434 119538 - K Ubiquitination 23000965 51434 119538 - K Ubiquitination 24816145

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID ANAPC7 Homo sapiens (Human) 259; 443; 65; 457; 433; 345 "259,NKNSVLKFEQAQM; 443,QRPDYIKAVVKKA; 65,YRNAVSKYTMALQ; 457,LLSREQKYEDGIA; 433,AKTLLDKALTQRP; 345,VQALLLKGAALRN" 259:21890473; 443:21890473; 65:21890473; 457:21890473; 433:21890473; 345:21890473 ANAPC7 Homo sapiens (Human) 259; 443; 65; 457; 433; 345 "259,NKNSVLKFEQAQM; 443,QRPDYIKAVVKKA; 65,YRNAVSKYTMALQ; 457,LLSREQKYEDGIA; 433,AKTLLDKALTQRP; 345,VQALLLKGAALRN" 259:21890473; 443:21890473; 65:21890473; 457:21890473; 433:21890473; 345:21890473 ANAPC7 Homo sapiens (Human) 258; 259; 442; 443; 64; 65; 457; 456; 432; 433; 345; 344 "258,NKNSVLKFEQAQM; 259,NKNSVLKFEQAQM; 442,QRPDYIKAVVKKA; 443,QRPDYIKAVVKKA; 64,YRNAVSKYTMALQ; 65,YRNAVSKYTMALQ; 457,LLSREQKYEDGIA; 456,LLSREQKYEDGIA; 432,AKTLLDKALTQRP; 433,AKTLLDKALTQRP; 345,VQALLLKGAALRN; 344,VQALLLKGAALRN" 258:21890473; 259:21890473; 442:21890473; 443:21890473; 64:21890473; 65:21890473; 457:21890473; 456:21890473; 432:21890473; 433:21890473; 345:21890473; 344:21890473 ANAPC7 Homo sapiens (Human) 477; 99; 293; 491; 467; 379 "477,QRPDYIKAVVKKA; 99,YRNAVSKYTMALQ; 293,NKNSVLKFEQAQM; 491,LLSREQKYEDGIA; 467,AKTLLDKALTQRP; 379,VQALLLKGAALRN" 477:21890473; 99:21890473; 293:21890473; 491:21890473; 467:21890473; 379:21890473 ANAPC7 Homo sapiens (Human) 259; 443; 65; 457; 433; 345 "259,NKNSVLKFEQAQM; 443,QRPDYIKAVVKKA; 65,YRNAVSKYTMALQ; 457,LLSREQKYEDGIA; 433,AKTLLDKALTQRP; 345,VQALLLKGAALRN" 259:21890473; 443:21890473; 65:21890473; 457:21890473; 433:21890473; 345:21890473 ANAPC7 Homo sapiens (Human) 259; 443; 65; 457; 433; 345 "259,NKNSVLKFEQAQM; 443,QRPDYIKAVVKKA; 65,YRNAVSKYTMALQ; 457,LLSREQKYEDGIA; 433,AKTLLDKALTQRP; 345,VQALLLKGAALRN" 259:21890473; 443:21890473; 65:21890473; 457:21890473; 433:21890473; 345:21890473 ANAPC7 Homo sapiens (Human) 288; 153; 477; 99; 293; 491; 193; 467; 379 "288,FRAGDNKNSVLKF; 153,TMLKQDKDAIAIL; 477,QRPDYIKAVVKKA; 99,YRNAVSKYTMALQ; 293,NKNSVLKFEQAQM; 491,LLSREQKYEDGIA; 193,PSVTSYKEVLRQC; 467,AKTLLDKALTQRP; 379,VQALLLKGAALRN" "288:21906983; 153:21906983; 477:21906983; 99:21906983; 293:21906983; 491:21906983; 193:21906983; 467:21906983; 379:21906983,22053931"